diphenhydramine has been researched along with antipyrine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (46.15) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Cruccu, G; Ferracuti, S; Innocenti, P; Leardi, MG; Prandi, P | 1 |
| Weiss, M | 1 |
| Evans, JI; Ogunremi, O | 1 |
| Browning, M; Crooks, J; O'Malley, K; Stevenson, IH | 1 |
| Campiglio, A | 1 |
| Haider, I | 1 |
| Joyce, CR; Morgan, H; Scott, DF | 1 |
| Burns, JJ; Harrison, YE; Welch, RM | 1 |
| Goodyear, MD; Hepburn, M; Johns, MW | 1 |
| Johnstone, M | 1 |
| Gürtler, J | 1 |
| Rhonheimer, C | 1 |
| FRANCHI, G | 1 |
| MEYER, HG | 1 |
| Hu, C; Hu, X; Qu, J; Yang, M; Yuan, F | 1 |
| Jiang, JG; Song, GS; Zhang, XR; Zhang, YH | 1 |
| Kim, S; Koyanagi, T; Yamaura, Y; Yamazaki, H; Yano, K | 1 |
| Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H | 1 |
4 trial(s) available for diphenhydramine and antipyrine
| Article | Year |
|---|---|
[Electric stimulation of the dental pulp in the evaluation of the central effect of analgesics].
Topics: Adult; Analgesics; Antipyrine; Benzocaine; Caffeine; Dental Pulp; Diphenhydramine; Diphenylacetic Acids; Dipyrone; Double-Blind Method; Drug Combinations; Drug Evaluation; Electric Stimulation; Ethylmorphine; Humans; Pain Measurement; Sensory Thresholds | 1990 |
Sleep and hypnotics: further experiments.
Topics: Adult; Amobarbital; Antipyrine; Chloral Hydrate; Diphenhydramine; Drug Tolerance; Humans; Male; Methaqualone; Placebos; Sleep; Sleep, REM; Substance Withdrawal Syndrome | 1970 |
A comparative trial of mandrax and dichloralphenazone.
Topics: Aged; Antipyrine; Chloral Hydrate; Clinical Trials as Topic; Diphenhydramine; Humans; Mental Disorders; Methaqualone; Middle Aged; Sleep Initiation and Maintenance Disorders | 1968 |
The effects of four hypnotic drugs and placebo on normal subjects' sleeping and dreaming at home.
Topics: Adult; Amobarbital; Antipyrine; Benzazepines; Clinical Trials as Topic; Diphenhydramine; Humans | 1970 |
22 other study(ies) available for diphenhydramine and antipyrine
| Article | Year |
|---|---|
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Use of metabolite AUC data in bioavailability studies to discriminate between absorption and first-pass extraction.
Topics: Absorption; Antipyrine; Biological Availability; Caffeine; Diphenhydramine; Dose-Response Relationship, Drug; Humans; Ketanserin; Lidocaine; Liver Diseases; Metronidazole; Nomifensine; Triamterene | 1990 |
Changes in human drug metabolism after long-term exposure to hypnotics.
Topics: Adolescent; Adult; Amobarbital; Antipyrine; Diphenhydramine; Drug Interactions; Humans; Hydrocortisone; Hypnotics and Sedatives; Methaqualone; Middle Aged; Nitrazepam; Phenylbutazone; Time Factors | 1972 |
[Determination of the N-methyl group in organic substances on the micro and decimomilligram scale].
Topics: Acetanilides; Aminopyrine; Antipyrine; Caffeine; Diphenhydramine; Ephedrine; Indicators and Reagents; Methylation; Microchemistry; Theobromine; Theophylline | 1973 |
Implications of enzyme induction in drug toxicity studies.
Topics: Animals; Antipyrine; Diphenhydramine; Dogs; Enzyme Induction; Female; Haplorhini; Liver; Male; Microsomes; Peptic Ulcer; Phenylbutazone; Probenecid; Rats; Tolbutamide | 1967 |
Use of hypnotic drugs by hospital patients.
Topics: Adult; Aged; Amobarbital; Antipyrine; Barbiturates; Diphenhydramine; Female; Hospitalization; Humans; Hypnotics and Sedatives; Male; Methaqualone; Middle Aged; Pentobarbital; Secobarbital; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep Wake Disorders; Substance-Related Disorders | 1971 |
The effects of oral sedatives on the vasoconstrictive reaction to fear.
Topics: Administration, Oral; Adolescent; Adult; Antipyrine; Barbiturates; Benperidol; Benzazepines; Blood Vessels; Chloral Hydrate; Chlormethiazole; Diazepam; Dilatation; Diphenhydramine; Drug Synergism; Fear; Fingers; Humans; Hypnotics and Sedatives; Methaqualone; Middle Aged; Plethysmography; Postoperative Care; Preoperative Care | 1971 |
[Clinical and respiratory function technical studies of the new drug combination Asthmadyn-R in asthmatic clinical states].
Topics: Adult; Aged; Antipyrine; Asthma; Atropa belladonna; Bronchodilator Agents; Diphenhydramine; Ephedrine; Female; Humans; Male; Middle Aged; Phenethylamines; Phytotherapy; Plants, Medicinal; Plants, Toxic; Respiratory Function Tests; Spirometry; Theophylline | 1967 |
[On the effect of Spondylon in the treatment of painful conditions of the locomotor system].
Topics: Antipyrine; Diphenhydramine; Flavonoids; Humans; Muscular Diseases; Pain | 1968 |
[Various derivatives of 1, 2-diphenyl-4-butylpyrazolidine-3, 5-dione. III. Quantitative determination].
Topics: Antipyrine; Biphenyl Compounds; Diphenhydramine; Ketones; Phenylbutazone | 1957 |
[SPONDYLON IN BATH REACTIONS IN PATIENTS WITH SPINAL DISEASES].
Topics: Aesculus; Antipyrine; Baths; Diphenhydramine; Drug Therapy; Fagaceae; Guaifenesin; Humans; Spinal Diseases | 1964 |
Degradation of selected pharmaceuticals in aqueous solution with UV and UV/H(2)O(2).
Topics: Antipyrine; Biodegradation, Environmental; Diphenhydramine; Hydrogen Peroxide; Ibuprofen; Kinetics; Oxidation-Reduction; Pesticide Residues; Phenytoin; Photochemistry; Photolysis; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical | 2009 |
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |
Age-related pharmacokinetic changes of acetaminophen, antipyrine, diazepam, diphenhydramine, and ofloxacin in male cynomolgus monkeys and beagle dogs.
Topics: Acetaminophen; Age Factors; Aging; Albumins; Animals; Antipyrine; Blood Proteins; Diazepam; Diphenhydramine; Dogs; Gastric Juice; Hydrogen-Ion Concentration; Macaca fascicularis; Male; Models, Animal; Ofloxacin | 2014 |
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine | 2021 |