diphenhydramine has been researched along with amantadine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H | 1 |
| Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Butzer, JF; Sahs, AL; Silver, DE | 1 |
| Bermanzohn, PC; Lipper, S | 1 |
| Bessen, HA; Snoey, ER | 1 |
| Florio, V; Longo, VG | 1 |
| Korduba, CA; Symchowicz, S; Veals, J | 1 |
| Bauman, AW; Hammond, EJ; Karas, BJ; Wilder, BJ | 1 |
| Kazzi, Z; Morgan, B; Patel, M; Schwartz, M | 1 |
| Jiang, JG; Song, GS; Zhang, XR; Zhang, YH | 1 |
1 review(s) available for diphenhydramine and amantadine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for diphenhydramine and amantadine
| Article | Year |
|---|---|
Amantadine in Parkinson's disease. A double-blind, placebo-controlled, crossover study with long-term follow-up.
Topics: Activities of Daily Living; Aged; Amantadine; Benztropine; Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Female; Follow-Up Studies; Humans; Locomotion; Long-Term Care; Male; Middle Aged; Muscle Rigidity; Parkinson Disease; Procyclidine; Time Factors; Tremor; Trihexyphenidyl | 1975 |
Treatment of valproate tremors.
Topics: Amantadine; Cyproheptadine; Diphenhydramine; Humans; Propranolol; Tremor; Valproic Acid | 1983 |
19 other study(ies) available for diphenhydramine and amantadine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution | 2011 |
Species independence in brain tissue binding using brain homogenates.
Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Letter: Electroconvulsive therapy in patients with parkinsonism.
Topics: Amantadine; Atropine; Depression; Diphenhydramine; Electroconvulsive Therapy; Female; Humans; Levodopa; Methohexital; Middle Aged; Parkinson Disease; Succinylcholine; Suicide | 1975 |
Acute psychosis after amantadine overdose.
Topics: Adult; Amantadine; Diagnosis, Differential; Diphenhydramine; Drug Synergism; Female; Hallucinations; Humans; Psychoses, Substance-Induced; Respiratory Tract Infections | 1990 |
Effects of amantadine and of some synthetic antiparkinsonian drugs on the behavioral response to L-DOPA in mice.
Topics: Amantadine; Amitriptyline; Animals; Antiparkinson Agents; Atropine; Behavior, Animal; Dihydroxyphenylalanine; Diphenhydramine; Drug Synergism; Imipramine; Mice; Orphenadrine; Parasympatholytics; Pargyline; Trihexyphenidyl | 1971 |
Inhibition of dopamine uptake into synaptosomes of rat corpus striatum by chlorpheniramine and its structural analogs.
Topics: Amantadine; Animals; Apomorphine; Brompheniramine; Chlorpheniramine; Cytoplasmic Granules; Diphenhydramine | 1971 |
Cardiotoxicity after massive amantadine overdose.
Topics: Adult; Amantadine; Antiparkinson Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; Cardiac Complexes, Premature; Diphenhydramine; Drug Overdose; Electrocardiography; Female; Heart Arrest; Heart Diseases; Histamine H1 Antagonists; Humans; Hypertension; Long QT Syndrome; Middle Aged; Pseudotumor Cerebri; Saline Solution, Hypertonic; Schizophrenia | 2008 |
[Rapid identification 15 effective components of anti common cold medicine with MRM by LC-MS/MS].
Topics: Acetaminophen; Acetanilides; Amantadine; Aminopyrine; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Antipyrine; Caffeine; Chlorpheniramine; Chromatography, Liquid; Diclofenac; Diphenhydramine; Drug Contamination; Drug Stability; Ephedrine; Guaifenesin; Promethazine; Pseudoephedrine; Reproducibility of Results; Salicylates; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2013 |