diphenhydramine and allopurinol

diphenhydramine has been researched along with allopurinol in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's0 (0.00)18.2507
2000's6 (40.00)29.6817
2010's6 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Huh, K; Iwata, H; Yamamoto, I1
Kalow, W1
Granger, DN; Korthuis, RJ; Taylor, AE; Townsley, MI1
Arias-Santiago, S; Husein-Elahmed, H; Orgaz-Molina, J; Soriano-Hernández, MI1

Reviews

2 review(s) available for diphenhydramine and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Ethnic differences in reactions to drugs and xenobiotics. Caffeine and other drugs.
    Progress in clinical and biological research, 1986, Volume: 214

    Topics: Acetylation; Caffeine; Cytochrome P-450 Enzyme System; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Gene Frequency; Genetic Markers; Humans; Kinetics; Methemoglobinemia; Mutagens; Phenylthiourea; Polymorphism, Genetic; Porphyrias; Racial Groups; Superoxide Dismutase; Taste; Xanthine Oxidase

1986

Other Studies

13 other study(ies) available for diphenhydramine and allopurinol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
[Hepatic allopurinol oxidizing enzyme in mice].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:2

    Topics: Aldehyde Oxidoreductases; Allopurinol; Animals; Chlorpromazine; Desipramine; Dexamethasone; Dialysis; Diphenhydramine; Hot Temperature; Imipramine; Ions; Liver; Male; Mice; Niacinamide; Oxypurinol; Testosterone; Time Factors; Vitamin K; Xanthine Oxidase

1975
The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability.
    Circulation research, 1985, Volume: 57, Issue:4

    Topics: Allopurinol; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Capillary Permeability; Catalase; Cimetidine; Dimethyl Sulfoxide; Diphenhydramine; Dogs; Female; Free Radicals; Ischemia; Male; Muscles; Osmotic Pressure; Oxygen; Superoxide Dismutase; Vascular Resistance

1985
[Angioedema due to losartan].
    Medicina clinica, 2011, Sep-10, Volume: 137, Issue:6

    Topics: Aged; Allopurinol; Angioedema; Angiotensin II Type 2 Receptor Blockers; Bradykinin; Diphenhydramine; Humans; Losartan; Male; Methylprednisolone

2011