Compounds > diphenhydramine

diphenhydramine and acetylcysteine

diphenhydramine has been researched along with acetylcysteine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chand, N; Diamantis, W; Harrison, JE; Rooney, S; Sofia, RD1
Bailey, B; McGuigan, MA1
Hayes, BD; Sarmiento, KF; Schwartz, EA1
Easter, JS; Ganetsky, M; Kimlin, EJ1
Bagdure, D; Heard, K; Monte, A; Wang, GS1
Rollstin, AD; Seifert, SA1
Lackey, G; McCulloh, RJ; Vyas, D1

Reviews

2 review(s) available for diphenhydramine and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Management of anaphylactoid reactions to intravenous N-acetylcysteine.
    Annals of emergency medicine, 1998, Volume: 31, Issue:6

    Topics: Acetaminophen; Acetylcysteine; Anaphylaxis; Anti-Allergic Agents; Diphenhydramine; Free Radical Scavengers; Histamine H1 Antagonists; Humans; Infusions, Intravenous; Practice Guidelines as Topic; Prospective Studies; Retrospective Studies

1998

Other Studies

8 other study(ies) available for diphenhydramine and acetylcysteine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Mucolytic activity of azelastine in mice and rats.
    Agents and actions, 1993, Volume: 38, Issue:3-4

    Topics: Acetylcysteine; Administration, Oral; Albuterol; Animals; Bromhexine; Carbocysteine; Diphenhydramine; Expectorants; Fluorescein; Fluoresceins; Histamine H1 Antagonists; Male; Mice; Phenolsulfonphthalein; Phthalazines; Potassium Iodide; Rats; Terbutaline; Trachea

1993
Development of hepatic failure despite use of intravenous acetylcysteine after a massive ingestion of acetaminophen and diphenhydramine.
    Annals of emergency medicine, 2009, Volume: 54, Issue:3

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Antidotes; Aspartate Aminotransferases; Charcoal; Diphenhydramine; Drug Combinations; Drug Overdose; Fatal Outcome; Female; Free Radical Scavengers; Histamine H1 Antagonists; Humans; Liver Failure; Middle Aged; Suicide, Attempted

2009
A 46-year-old woman with altered mental status and garbled speech.
    The Journal of emergency medicine, 2009, Volume: 37, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Diagnosis, Differential; Diphenhydramine; Electrocardiography; Female; Humans; Mental Disorders; Middle Aged; Poisoning; Speech Disorders; Spinal Puncture; Tomography, X-Ray Computed

2009
Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose.
    Pediatrics, 2011, Volume: 127, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Child; Cholinergic Antagonists; Diphenhydramine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Overdose; Female; Free Radical Scavengers; Half-Life; Hepatic Encephalopathy; Humans; Infusions, Intravenous; Intensive Care Units, Pediatric; International Normalized Ratio; Liver Failure; Liver Function Tests; Metabolic Clearance Rate; Suicide, Attempted

2011
Acetaminophen/diphenhydramine overdose in profound hypothermia.
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:1

    Topics: Acetaminophen; Acetylcysteine; Adult; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injury; Cholinergic Antagonists; Diphenhydramine; Drug Combinations; Drug Overdose; Female; Humans; Hypothermia; Infusions, Intravenous; Nonprescription Drugs; Rewarming; Treatment Outcome

2013
Acute overdose: suicide attempt.
    Simulation in healthcare : journal of the Society for Simulation in Healthcare, 2013, Volume: 8, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adolescent; Antidotes; Charcoal; Diphenhydramine; Drug Overdose; Education, Pharmacy; Electrocardiography; Female; Humans; Seizures; Suicide, Attempted

2013