Page last updated: 2024-09-03

diperdipine and nicardipine

diperdipine has been researched along with nicardipine in 1 studies

*Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [MeSH]

*Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents. [MeSH]

Compound Research Comparison

Studies
(diperdipine)
Trials
(diperdipine)
Recent Studies (post-2010)
(diperdipine)
Studies
(nicardipine)
Trials
(nicardipine)
Recent Studies (post-2010) (nicardipine)
5002,646444312

Protein Interaction Comparison

ProteinTaxonomydiperdipine (IC50)nicardipine (IC50)
Bile salt export pumpHomo sapiens (human)8.314
ATP-dependent translocase ABCB1Mus musculus (house mouse)8
ATP-dependent translocase ABCB1Homo sapiens (human)4.2992
Cytochrome P450 3A4Homo sapiens (human)0.42
Cytochrome P450 2C9 Homo sapiens (human)1.69
ATP-dependent translocase ABCB1Mus musculus (house mouse)2.5
Cytochrome P450 2J2Homo sapiens (human)1.69
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)4.925
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)4.8

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Angignard, D; Cahn, J; Greiner, PO1

Other Studies

1 other study(ies) available for diperdipine and nicardipine

ArticleYear
High performance liquid chromatography of a new 1,4-dihydropyridine: applications to pharmacokinetic study in dogs.
    Journal of pharmaceutical sciences, 1988, Volume: 77, Issue:5

    Topics: Administration, Oral; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dogs; Indicators and Reagents; Injections, Intravenous; Light; Male; Nicardipine; Nifedipine; Nitrendipine

1988