dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination has been researched along with phosphorylcholine in 207 studies
| Studies (dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination) | Trials (dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination) | Recent Studies (post-2010) (dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination) | Studies (phosphorylcholine) | Trials (phosphorylcholine) | Recent Studies (post-2010) (phosphorylcholine) |
|---|---|---|---|---|---|
| 219 | 84 | 3 | 5,308 | 255 | 1,893 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.97) | 18.7374 |
| 1990's | 170 (82.13) | 18.2507 |
| 2000's | 31 (14.98) | 29.6817 |
| 2010's | 4 (1.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galan, HL; Kuehl, TJ | 1 |
| Autret, E; Laugier, J; Nasr, C; Saliba, E; Suc, AL | 1 |
| Aebi, C; Bachmann, D; Pfenninger, J; Wagner, BP | 1 |
| Balaraman, V; Barrett, J; Easa, D; Ibarra-Pratt, E; Loo, SW; Nakamura, KT; Pelke, S; Smith, MB | 1 |
| Ariagno, RL; Armsby, DH; Baldwin, R; Bellon, G; Carlisle, K; Long, W; Rector, D; Stevenson, DK | 1 |
| Antal, JM; Connors, MJ; Meeker, DP; Thomassen, MJ; Wiedemann, HP | 2 |
| King, M; Ramirez, O; Rubin, BK | 1 |
| Bhatt-Mehta, V; Schumacher, RE | 1 |
| Cummings, JJ; Egan, EA; Ferguson, WH; Holm, BA; Hudak, BB; Hudak, ML | 1 |
| Ashton, MR; Austin, NC; Hall, MA; Normand, IC; Postle, AD; Smith, DE | 1 |
| Sekar, KC; Toubas, PL; Wallenbrock, MA | 1 |
| Courtney, SE | 1 |
| Bose, G | 1 |
| Dechant, KL; Faulds, D | 1 |
| Hall, SB; Holm, BA; Notter, RH; Venkitaraman, AR; Whitsett, JA | 1 |
| Bose, C; Bose, G; Corbet, A; Edwards, K; Prats, JG; Russell, L | 1 |
| Abbasi, S; Bhutani, VK; Gerdes, JS; Long, WA | 1 |
| Bosque, E; Goldman, SL; Lewis, K; McCann, E | 1 |
| Bard, H; Bourgeois, M; Chessex, P; Hazan, J; Long, W; Piedboeuf, B | 1 |
| Anday, E; Easa, D; Gong, A; LeBlanc, M; Long, W; Pauly, T; Pramanik, A; Sell, M; Stevenson, D; Walther, F | 1 |
| Gerdes, J; Long, W; Whitsett, J | 1 |
| Derleth, D; Finer, N; Long, W; McMurray, B; Mullett, M; Peliowski, A; Sankaran, K; van Houten, J; Walker, D; Wold, D | 1 |
| Allen, A; Boros, S; Corbet, A; Edwards, K; Gerdes, J; Houle, L; Long, W; McMillan, D; Schiff, D; Vaughan, R | 1 |
| Prevost, RR | 1 |
| Edwards, DK; Levine, D; Merritt, TA | 1 |
| Bard, H; Chernick, V; Corbet, A; Cotton, R; Courtney, S; Long, W; McGuiness, G; Smyth, J; Walter, D; Watts, J | 1 |
| Corbet, AJ; Garcia-Prats, JA; Lombardy, LR; Long, WA; Murphy, DJ; Wold, DE | 1 |
| Bucciarelli, R; Corbet, A; Goldman, S; Long, W; Mammel, M; Wold, D | 1 |
| Ma, EJ; van de Bor, M; Walther, FJ | 1 |
| Guthrie, R; Long, W; Schumacher, R; Sundell, H; Thompson, T; Volberg, F | 1 |
| Ballard, RA; Clements, JA; Heilbron, DC; Phibbs, CS; Phibbs, RH; Schlueter, MA; Sniderman, SH; Tooley, WH; Wakeley, A | 1 |
| Etches, PC; Finer, NN; Peliowski, A; Tierney, AJ | 1 |
| Nightingale, SL | 1 |
| Bose, C; Bose, G; Corbet, A; Donlon, D; Garcia-Prats, J; Lombardy, L; Long, W; Wold, D | 1 |
| Escudier, BJ; Hoeffel, JM; Murray, JF; Zelter, M | 1 |
| Brown, CL; Clements, JA; Muramatsu, K; Schlueter, MA; Tooley, WH | 1 |
| Ballard, P; Clements, JA; Clyman, RI; Durand, DJ; Heymann, MA; Kitterman, J; Mauray, F | 1 |
| Beume, R; Häfner, D; Kilian, U; Krasznai, G; Lachmann, B | 1 |
| Antal, JM; Divis, LT; Thomassen, MJ; Wiedemann, HP | 1 |
| Costard-Jäckle, A; Cremer, J; Harringer, W; Haverich, A; Hirt, SW; Strüber, M | 1 |
| Halliday, HL | 1 |
| Carlo, WA; Cifuentes, J; Matalon, S; Myles, C; Nieves, B; Ruiz-Oronoz, J | 1 |
| Fawcett, TA; Fracica, PJ; Huang, YC; Menache, MG; Moon, RE; Piantadosi, CA; Sane, AC; Simonson, SG; Young, SL | 1 |
| Crapo, JD; Duhaylongsod, FG; Fracica, PJ; Huang, YC; Piantadosi, CA; Welty-Wolf, KE; Young, SL | 1 |
| Franks, C; Perez-Benavides, F; Riff, E | 1 |
| David-Cu, R; Findlay, RD; Taeusch, HW; Walther, FJ | 1 |
| Doig, C | 1 |
| Easa, D; Long, W; Mullett, M; Schumacher, R; Sundell, H; Walther, FJ | 1 |
| Cotton, R; Guthrie, R; Hirata, T; LeBlanc, M; Long, W; Mammel, M; Sell, M | 1 |
| Beaumont, E; Cook, L; Dhanireddy, R; Gerdes, J; Gerdes, M; Jarret, R; Kopleman, A; Long, W | 1 |
| Asbill, D; Bose, CL; Corbet, AJ; Edwards, K; Garcia-Prats, J; Kraybill, EN; Long, W | 1 |
| Bard, H; Conway, B; Courtney, SE; Long, W; McMillan, D; Sauve, R; Thompson, T; Walter, D | 1 |
| Corbet, A; Cotton, R; Gerdes, J; Long, W; Schumacher, R | 1 |
| Bingham, W; Casiro, O; Long, W; MacMurray, B; Saigal, S; Vincer, M; Whitfield, M | 1 |
| Bingham, W; Casiro, O; Long, W; MacMurray, B; Robertson, C; Saigal, S; Sankaran, K; Whitfield, M | 1 |
| Anday, E; Boros, S; Bucciarelli, R; Burchfield, D; Gong, A; Long, W; Zucker, J | 1 |
| Bard, H; Derleth, D; Long, W; Pauly, T; Robertson, C; Sauve, R; Stevenson, D; Vincer, M | 1 |
| Allen, A; Long, W; MacMurray, B; Peliowski, A; Sankaran, K; Shukla, A; Smyth, J; Volberg, F | 1 |
| Bard, H; Chernick, V; Finer, N; Krzeski, R; Long, W; McMillan, D; Schiff, D; Watts, J | 1 |
| Avila, E; Cook, L; Corbet, A; Edwards, K; Gerdes, J; Long, W; Puri, A; Rosenberg, A | 1 |
| Hamdan, AH; Shaw, NJ | 2 |
| Bent, RC; Davis, JM; Merritt, TA; Peabody, SS; Slayter, MV; Wiswell, TE | 1 |
| Berggren, P; Corcoran, JD; Curstedt, T; Halliday, HL; Robertson, B; Sun, B | 1 |
| Laugier, J; Nashashibi, M; Nasr, C; Saliba, E; Vaillant, MC | 1 |
| Kääpä, P; Kero, P; Seppänen, M | 1 |
| Klein, JM; Patel, CA | 1 |
| Bernstein, G; Cleary, JP; Heldt, GP; Mannino, FL | 1 |
| Fuhrman, BP; Hernan, LJ; Holm, B; Leach, CL; Morin, FC; Papo, MC; Steinhorn, D | 1 |
| Allen, JN; Marsh, CB; Moore, SA; Pope-Harman, AL; Wewers, MD | 1 |
| Apere, H; Choukroun, ML; Demarquez, JL; Fayon, M; Galperine, RI; Guenard, H; Llanas, B | 1 |
| Billman, D; Nicks, J; Schumacher, R | 1 |
| Katumba, JJ; McBrien, M; Mukhtar, AI | 1 |
| Balk, RA; Horton, J; Jenkinson, SG; Pattishall, EN; Shah, JB; Tharratt, RS; Weg, JG; Zaccardelli, D | 1 |
| Buck, R; Garland, J; Weinberg, M | 1 |
| Soll, RF; Tarnow-Mordi, WO | 1 |
| Bartmann, P; Woerndle, S | 1 |
| Campbell, LA; Curstedt, T; Gunkel, JH; Long, WA; Merritt, TA; Robertson, B; Sherman, MP | 1 |
| Bongrani, S; Fornasier, M; Papotti, M; Razzetti, R; Robertson, B | 1 |
| Cheah, IG; Lim, NL; Nordin, MM | 1 |
| al-Hifzi, I; Khan, M; Majeed-Saidan, MA | 1 |
| Gore, SM | 1 |
| Robertson, B; Speer, CP | 1 |
| Morley, C | 1 |
| Tarnow-Mordi, W | 1 |
| Rogers, D | 2 |
| Hoffman, DR; Johnston, JM; Moya, FR; Zhao, B | 1 |
| Glover, RM; Laing, IA; Parry, GJ; Stenson, BJ; Tarnow-Mordi, WO; Wilkie, RA | 1 |
| Chatfield, SL; Dear, PR; Kelly, EJ | 1 |
| Corkey, C; Jenkins, J; Rollins, M; Tubman, R; Wilson, D | 1 |
| Ewing, CK; Richards, T; Sehgal, SS; Taeusch, HW | 1 |
| Andersson, S; Hallman, M; Heikinheimo, M; Hynynen, M; Kukkonen, S; Rautiainen, P | 1 |
| Coleman, RE; MacIntyre, N; Pattishall, E; Snyder, G; Zaccardelli, D | 1 |
| Bourchier, D; Broadbent, R; Darlow, B; Knight, D; Selby, R; Wach, R | 1 |
| Chan, JO; Darrow, KA; Kim, AH; Marks, KH; Moglia, BA; Reeves, IV; Seaton, JF | 1 |
| Robertson, B; Sangstad, OD | 1 |
| Amirkhanian, JD; Cross, CE; Halliwell, B; Helbock, H; Merritt, TA | 1 |
| Clark, WR; Feldbaum, DM; Hakim, TS; Nieman, GF; Paskanik, M; Wormuth, D | 1 |
| Bauer, CR; Fanaroff, AA; Fletcher, BD; Horbar, JD; Korones, SB; Oh, W; Shankaran, S; Soll, RF; Wright, EC; Wright, LL | 1 |
| Phibbs, CS; Phibbs, RH; Schlueter, MA; Sniderman, S; Tooley, WH; Wakeley, A | 1 |
| Cotton, RB; Law, AB; Lindstrom, DP; Olsson, T; Parker, RA; Sandberg, K; Silberberg, AR; Sundell, HW | 1 |
| Diwaker, K; John, E; Roberts, S | 1 |
| Bratlid, D; Farstad, T | 1 |
| Abbasi, S; Bhutani, VK; Gerdes, JS | 1 |
| Jobe, AH | 1 |
| Amato, M | 1 |
| Bossi, E; Brunner-Di Pietro, D; Koerner, F | 1 |
| Halley, GC; Laing, IA; McIntosh, M; Stenson, BJ | 1 |
| Agarwal, R; Alba, J; Hegyi, T; Hiatt, IM | 1 |
| Balaraman, V; Britton, B; Easa, D; Finn, KC; Sood, SL; Uyehara, CF | 1 |
| Anzueto, A; Baughman, RP; Guntupalli, KK; Lemaire, F; Long, W; Pattishall, EN; Raventós, AA; Weg, JG; Wiedemann, HP; Zaccardelli, DS | 1 |
| Matthay, MA | 1 |
| Brandt, M; Cremer, J; Harringer, W; Haverich, A; Hirt, SW; Strüber, M | 1 |
| Balaraman, V; Easa, D; Finn, KC; Hashiro, G; Sood, SL; Uyehara, CF | 1 |
| Clarke, MP; Fritz, S; Pennefather, PM; Strong, NP; Tin, W | 1 |
| Ishisaka, DY | 1 |
| Claris, O; Grandjean, H; Hascoët, JM; Lenoir, S | 1 |
| Antal, JM; Barna, BP; Divis, LT; Meeker, DP; Thomassen, MJ; Wiedemann, HP | 1 |
| Auten, RL; Balsan, MJ; Belcastro, MR; Brody, AS; Buckwald, S; Carrion, V; Donohue, PK; Durand, DJ; Egan, EA; Farrell, EE; Graeber, JE; Horgan, MJ; Hudak, ML; Jansen, RD; Jung, AL; Laskay, KM; Maniscalco, WW; Martin, DJ; Matteson, EJ; Miller, RR; Montgomery, P; Riddlesberger, MM; Rosenberg, AA; Torres, BA | 1 |
| Bruni, R; David-Cu, R; Fan, BR; Taeusch, HW; Walther, FJ | 1 |
| Jeffery, HE; Skelton, R | 1 |
| Malathi, I; Ng, KC | 1 |
| Bartmann, P; Neumeister, B; Woerndle, S | 1 |
| Czopf, L; Holm, BA; Matalon, S; Pataki, G | 1 |
| Aiba, T; Fujiwara, T; Hashimoto, Y; Sakai, K; Takei, T | 1 |
| Choukroun, ML; Demarquez, JL; Fayon, M; Galpérine, I; Guénard, H; Kays, C; Todd, DA | 1 |
| Belik, J; Duncan, JE; Hatch, GM | 1 |
| Amato, M; Bachofen, H; Burri, PH; Grunder, R; Schürch, S | 1 |
| Balaraman, V; Easa, D; Finn, KC; Mundie, TG; Sood, SL; Wilkerson, SY | 1 |
| Bassiouny, MR; Cherian, E; Remo, C | 1 |
| Tsan, GL; Tsan, MF; White, JE | 1 |
| Santeiro, ML; Wyble, L | 1 |
| Asselin, JM; Auten, RL; Belcastro, MR; Brody, AS; Cummings, NJ; Donohue, PK; Egan, EA; Hamm, CR; Hudak, ML; Jansen, RD; Jung, AL; Kimberlin, LV; Martin, DJ; Matteson, EJ; Montgomery, P; Riddlesberger, MM; Rosenberg, AA | 1 |
| Bastida, J; Del Barco, M; Grandzoto, J; Hayward, PE; Margotto, P; Martell, M; Peña, J; Rossello, JD; Villanueva, D | 1 |
| Anzueto, A; Barrett, J; Colice, G; Engle, M; Jubran, A; Ohar, JA; Pattishall, EN; Perret, KA; Piquette, CA; Rennard, SI; Rubin, BK | 1 |
| Guo, Y; Manuel, SM; Matalon, S | 1 |
| Jacobs, HC; Llanos, AJ; Moraga, FA; Moya, FR; Ríos, AM; Riquelme, RA; Rubio, LA; Salvo, HD | 1 |
| Cotton, RB; Lindstrom, DP; Parker, RA; Sandberg, KL; Sjöqvist, BA | 1 |
| Alderson, PO; Domingues, C; Mitra, A; Suga, K | 1 |
| al-Essa, M; Dolovich, M; Fok, TF; Kirpalani, H; Rasid, F | 1 |
| Heldin, P; Johnsson, H; Laurent, TC; Sedin, G | 1 |
| Kempley, ST; Murdoch, E | 2 |
| Balaraman, V; Easa, D; Egan, E; Killeen, J; Ku, TL; Meister, J; Sood, SL; Tam, E; Uyehara, CF | 1 |
| Husain, AN; Siddiqui, NH; Stocker, JT | 1 |
| Iarŭkova, N | 1 |
| McMillan, DD; Schürch, S; Shukla, AK; Singhal, N | 1 |
| Dobner, M; Helbich, TH; Herold, CJ; Popow, C; Wunderbaldinger, P; Zekert, M | 1 |
| Baker, JR; Chen, C; Kukowska-Latallo, JF; Raczka, E; Rymaszewski, M | 1 |
| Rubin, BK | 2 |
| Gadek, JE | 1 |
| John, E; Lloyd, J; Todd, DA | 1 |
| Merchant, RH; Sanghvi, KP | 1 |
| Dimitriou, G; Forsling, M; Greenough, A; Kavvadia, V | 1 |
| Cirillo, F; Diurno, F; Imperatore, F; Liguori, G; Pica, M; Postiglione, M | 1 |
| Gebara, BM; Kroupa-Kulik, M | 1 |
| Al Khusaiby, SM; da Costa, DE; Pai, MG | 1 |
| al-Essa, M; Bowen, B; Coates, G; Dolovich, M; Fok, TF; Kirpalani, H; Monkman, S | 1 |
| Frey, B; Keller, E; Losa, M | 1 |
| Cremer, J; Harringer, W; Haverich, A; Hirt, SW; Strüber, M | 1 |
| Baker, JR; Bielinska, AU; Chen, C; Eichman, J; Kukowska-Latallo, JF | 1 |
| Bowman, ED; Mildenhall, LF; Pavuluri, NN | 1 |
| Germann, PG; Häfner, D | 1 |
| Babakhanov, ISh; Fortinskaia, ES; Khalilov, EM; Kochetova, MM; Torkhovskaia, TI; Zakharova, TS | 1 |
| Soll, RF | 1 |
| Beghetti, M; Berner, M; Hanquinet, S; Rimensberger, PC | 1 |
| Halliday, HL; Robertson, B; Speer, CP | 1 |
| Fellman, V; Ikonen, S; Järvenpää, AL; Kukkonen, AK; Pokela, ML; Virtanen, M | 1 |
| Blau, H; Hoffman, V; Kalina, M; Riklis, S | 1 |
| Herting, E; Möller, O; Rauprich, P; Robertson, B; Walter, G | 1 |
| Allen, A; Allen, V; MacDonald, J; Oulton, M; Stinson, D | 1 |
| Bogdanova, V; Chernookova, V; Efremova, R; Nedeva, N; Tsvetkova, S | 1 |
| Alderson, PO; Domingues, C; Matsunaga, N; Mitra, A; Ogasawara, N; Rescigno, J; Sasai, K; Smith, LG; Suga, K | 1 |
| Banerjee, R; Bellare, JR | 2 |
| Dutta, S; Kumar, P; Kumar, R; Narang, A | 1 |
| Soll, RF; Suresh, GK | 1 |
| Holm, BA; King, DM; Notter, RH; Palmer, HJ; Wang, Z | 1 |
| Baughman, RP; Gunther, KL; Henderson, RF; Keeton, DA; Pattishall, EN; Rashkin, MC; Waide, JJ; Whitsett, J; Zaccardelli, DS | 1 |
| Christodoulaki, M; Giannakopoulou, C; Hatzidaki, E; Korakaki, E; Mamoulakis, D; Margari, KM | 1 |
| Amis, TC; Christenson, HK; Garlick, SR; Kairaitis, K; Kirkness, JP; Parikh, R; Wheatley, JR | 1 |
| Amato, M; Doyle, CA; Fiore, HH; Frantz, ID; Nielsen, HC; Petit, K | 1 |
| Brackenbury, A; Lewis, JF | 1 |
| Ballard, PL; Ballard, RA; Godinez, MH; Godinez, RI; Merrill, JD; Truog, WE | 1 |
| Carlo, WA; St John, EB | 1 |
| Bevilacqua, G; Parmigiani, S | 1 |
| Moen, MD; Perry, CM; Wellington, K | 1 |
| Bhutani, VK; Bowen, FW; Sivieri, EM | 1 |
| Banerjee, R; Huilgol, N; Preetha, A | 1 |
| Georgiev, GA; Georgieva, R; Iordanova, A; Khristova, E; Lalchev, Z; Petkova, Kh; Stoimenova, E; Todorov, R; Vasiliev, Kh | 1 |
| Castro, R; Dixon, PS; Kerecman, J; Mustafa, SB; Vasquez, MM | 1 |
| Lal, MK; Sinha, SK | 1 |
| Moya, F | 1 |
| Carlos, RQ; Davonzo, C; Dimaguila, MA; Gal, P; McPherson, C; Ransom, JL; Smith, M; Wimmer, JE | 1 |
| Bahadue, FL; Soll, R | 1 |
| Hawtrey, A; Smith, J; van Zyl, JM | 1 |
| Cao, HY; Han, D; Jiang, H; Wu, HM; Wu, S; Yuan, LJ; Zhang, L; Zhao, S | 1 |
14 review(s) available for dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination and phosphorylcholine
| Article | Year |
|---|---|
Delayed compliance increase in infants with respiratory distress syndrome following synthetic surfactant.
Topics: Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Lung Compliance; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Gas Exchange; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Time Factors | 1992 |
Colfosceril palmitate. A review of the therapeutic efficacy and clinical tolerability of a synthetic surfactant preparation (Exosurf Neonatal) in neonatal respiratory distress syndrome.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Double-Blind Method; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Overview of clinical trials comparing natural and synthetic surfactants.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn | 1995 |
Artificial versus natural surfactant--can we base clinical practice on a firm scientific footing?
Topics: Biological Products; Clinical Trials as Topic; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1994 |
Exogenous surfactant use in neonates.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1996 |
Therapeutic aerosols and airway secretions.
Topics: Aerosols; Animals; Anti-Asthmatic Agents; Asthma; Cystic Fibrosis; Drug Combinations; Fatty Alcohols; Humans; Mucociliary Clearance; Mucous Membrane; Mucus; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory System | 1996 |
Consensus on surfactant and inhaled nitric oxide for ARDS.
Topics: Administration, Inhalation; Adult; Aerosols; Animals; Biological Products; Cattle; Drug Combinations; Fatty Alcohols; Humans; Instillation, Drug; Nitric Oxide; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome | 1996 |
Natural surfactant extract versus synthetic surfactant for neonatal respiratory distress syndrome.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 2000 |
Role of exogenous surfactant in acute lung injury.
Topics: Clinical Trials as Topic; Drug Combinations; Fatty Alcohols; Humans; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Surface-Active Agents; Treatment Outcome | 2003 |
Lucinactant: in neonatal respiratory distress syndrome.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Animals, Newborn; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intercellular Signaling Peptides and Proteins; Peptides; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Surface Tension; Treatment Outcome | 2005 |
Surfactant respiratory therapy using Surfaxin/sinapultide.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Peptides; Phosphatidylglycerols; Phosphorylcholine; Polyethylene Glycols; Polymyxin B; Proteins; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 2008 |
Synthetic surfactants: where are we? Evidence from randomized, controlled clinical trials.
Topics: Animals; Biological Products; Bronchopulmonary Dysplasia; Dose-Response Relationship, Drug; Drug Combinations; Evidence-Based Medicine; Fatty Alcohols; Follow-Up Studies; Humans; Infant, Newborn; Intensive Care, Neonatal; Phosphatidylglycerols; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Proteins; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn; Survival Rate; Treatment Outcome | 2009 |
Early versus delayed selective surfactant treatment for neonatal respiratory distress syndrome.
Topics: Acute Disease; Acute Lung Injury; Chronic Disease; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn; Time Factors | 2012 |
Effect of exogenous pulmonary surfactants on mortality rate in neonatal respiratory distress syndrome: A network meta-analysis of randomized controlled trials.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Phosphatidylglycerols; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Proteins; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn | 2015 |
81 trial(s) available for dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination and phosphorylcholine
| Article | Year |
|---|---|
Early or selective surfactant (colfosceril palmitate, Exosurf) for intubated babies at 26 to 29 weeks gestation. A European double-blind trial with sequential analysis. European Exosurf Study Group.
Topics: Brain Diseases; Cysts; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Female; Gestational Age; Humans; Hydrocephalus; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome; Ultrasonography | 1992 |
Early versus delayed neonatal administration of a synthetic surfactant--the judgment of OSIRIS. The OSIRIS Collaborative Group (open study of infants at high risk of or with respiratory insufficiency--the role of surfactant.
Topics: Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant; Infant, Newborn; Oxygen Consumption; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Risk Factors; Treatment Outcome | 1992 |
Surfactant for babies.
Topics: Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Exosurf treatment investigational new drug phase: effect of an individualized third dose in infants with respiratory distress syndrome.
Topics: Drug Administration Schedule; Drug Combinations; Drugs, Investigational; Fatty Alcohols; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Retrospective Studies | 1992 |
Mucus rheology and transport in neonatal respiratory distress syndrome and the effect of surfactant therapy.
Topics: Drug Combinations; Elasticity; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Mucociliary Clearance; Mucus; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Rheology; Viscosity | 1992 |
Turnover of exogenous artificial surfactant.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Birth Weight; Chromatography, High Pressure Liquid; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Infant, Newborn; Intubation, Intratracheal; Phosphatidylcholines; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Colfosceril palmitate. A review of the therapeutic efficacy and clinical tolerability of a synthetic surfactant preparation (Exosurf Neonatal) in neonatal respiratory distress syndrome.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Double-Blind Method; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Results of laboratory surveillance of very low birth weight infants treated with a synthetic surfactant.
Topics: Blood; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1992 |
Pulmonary mechanics and energetics in preterm infants who had respiratory distress syndrome treated with synthetic surfactant.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests; Respiratory Mechanics | 1992 |
Pulmonary mechanics in premature infants one month after treatment with synthetic surfactant.
Topics: Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Function Tests; Respiratory Mechanics | 1992 |
Energy expenditure during synthetic surfactant replacement therapy for neonatal respiratory distress syndrome.
Topics: Calorimetry, Indirect; Drug Combinations; Energy Metabolism; Fatty Alcohols; Humans; Infant, Low Birth Weight; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Controlled trial of a single dose of synthetic surfactant at birth in premature infants weighing 500 to 699 grams. The American Exosurf Neonatal Study Group I.
Topics: Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Double-Blind Method; Drug Combinations; Ductus Arteriosus, Patent; Fatty Alcohols; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Survival Analysis | 1992 |
Elastase activity and surfactant protein concentration in tracheal aspirates from neonates receiving synthetic surfactant.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Pancreatic Elastase; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Trachea | 1992 |
Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
Topics: Autopsy; Double-Blind Method; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Incidence; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Retrospective search for bleeding diathesis among premature newborn infants with pulmonary hemorrhage after synthetic surfactant treatment. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
Topics: Double-Blind Method; Drug Combinations; Fatty Alcohols; Hemorrhagic Disorders; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Retrospective Studies | 1992 |
A controlled trial of synthetic surfactant in infants weighing 1250 g or more with respiratory distress syndrome. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
Topics: Birth Weight; Bronchopulmonary Dysplasia; Child; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature, Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Ventilator Weaning | 1991 |
Reduced mortality in small premature infants treated at birth with a single dose of synthetic surfactant.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Fatty Alcohols; Follow-Up Studies; Humans; Incidence; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Decreased mortality rate among small premature infants treated at birth with a single dose of synthetic surfactant: a multicenter controlled trial. American Exosurf Pediatric Study Group 1.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Survival Rate | 1991 |
Cerebral blood flow velocity after surfactant instillation in preterm infants.
Topics: Blood Flow Velocity; Cerebral Hemorrhage; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Effects of two rescue doses of a synthetic surfactant on mortality rate and survival without bronchopulmonary dysplasia in 700- to 1350-gram infants with respiratory distress syndrome. The American Exosurf Neonatal Study Group I.
Topics: Bronchopulmonary Dysplasia; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant, Low Birth Weight; Infant, Newborn; Outcome and Process Assessment, Health Care; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Initial clinical trial of EXOSURF, a protein-free synthetic surfactant, for the prophylaxis and early treatment of hyaline membrane disease.
Topics: Administration, Inhalation; Birth Weight; Drug Combinations; Drug Evaluation; Fatty Alcohols; Follow-Up Studies; Humans; Hyaline Membrane Disease; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Recurrence; Regression Analysis; Respiration, Artificial; Time Factors | 1991 |
Improved outcome at 28 days of age for very low birth weight infants treated with a single dose of a synthetic surfactant.
Topics: Bronchopulmonary Dysplasia; Cause of Death; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Incidence; Infant, Low Birth Weight; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Survival Rate | 1990 |
Adult respiratory distress syndrome and artificial surfactant replacement in the pediatric patient.
Topics: Child; Child, Preschool; Drug Combinations; Fatty Alcohols; Female; Humans; Infant; Male; Near Drowning; Oxygen Consumption; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Respiratory Function Tests; Retrospective Studies | 1995 |
One-year follow-up of 66 premature infants weighing 500 to 699 grams treated with a single dose of synthetic surfactant or air placebo at birth: results of a double-blind trial. American Exosurf Neonatal Study Group I.
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Hospitalization; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Lung Diseases; Male; Neurologic Examination; Phosphorylcholine; Polyethylene Glycols; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
One-year follow-up of 273 infants with birth weights of 700 to 1100 grams after prophylactic treatment of respiratory distress syndrome with synthetic surfactant or air placebo. American Exosurf Neonatal Study Group I.
Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Hospitalization; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Male; Neurologic Examination; Phosphorylcholine; Polyethylene Glycols; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
Health and neurodevelopmental outcome at 1-year adjusted age in 508 infants weighing 700 to 1100 grams who received prophylaxis with one versus three doses of synthetic surfactant. American Exosurf Neonatal Study Groups I and II.
Topics: Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Humans; Infant Mortality; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Male; Nervous System Diseases; Neurologic Examination; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
Double-blind evaluation of developmental and health status to age 2 years of infants weighing 700 to 1350 grams treated prophylactically at birth with a single dose of synthetic surfactant or air placebo.
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Nervous System Diseases; Neurologic Examination; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
Double-blind 1-year follow-up of 1540 infants with respiratory distress syndrome randomized to rescue treatment with two doses of synthetic surfactant or air in four clinical trials. American and Canadian Exosurf Neonatal Study Groups.
Topics: Air; Birth Weight; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Humans; Infant, Newborn; Male; Nervous System Diseases; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
Double-blind developmental evaluation at 1-year corrected age of 597 premature infants with birth weights from 500 to 1350 grams enrolled in three placebo-controlled trials of prophylactic synthetic surfactant. American Exosurf Neonatal Study Group I.
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Neurologic Examination; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
One-year follow-up of 89 infants with birth weights of 500 to 749 grams and respiratory distress syndrome randomized to two rescue doses of synthetic surfactant or air placebo. Canadian Exosurf Neonatal Study Group. Canadian Exosurf Neonatal Follow-Up Gro
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Nervous System Diseases; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
One-year outcome in 232 premature infants with birth weights of 750 to 1249 grams and respiratory distress syndrome randomized to rescue treatment with two doses of synthetic surfactant or air placebo. Canadian Exosurf Neonatal Study Group.
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Health Status; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Nervous System Diseases; Phosphorylcholine; Polyethylene Glycols; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
One-year follow-up evaluation of 260 premature infants with respiratory distress syndrome and birth weights of 700 to 1350 grams randomized to two rescue doses of synthetic surfactant or air placebo. American Exosurf Neonatal Study Group I.
Topics: Air; Child Development; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Hospitalization; Humans; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Male; Nervous System Diseases; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity | 1995 |
Outcome at 1-year adjusted age of 957 infants weighing more than 1250 grams with respiratory distress syndrome randomized to receive synthetic surfactant or air placebo. American and Canadian Exosurf Neonatal Study Groups.
Topics: Air; Child Development; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Male; Nervous System Diseases; Phosphorylcholine; Polyethylene Glycols; Psychomotor Performance; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1995 |
Double-blind, randomized, placebo-controlled Canadian multicenter trial of two doses of synthetic surfactant or air placebo in 224 infants weighing 500 to 749 grams with respiratory distress syndrome. Canadian Exosurf Neonatal Study Group.
Topics: Air; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Survival Rate | 1995 |
Effects of two rescue doses of synthetic surfactant in 344 infants with respiratory distress syndrome weighing 750 to 1249 grams: a double-blind, placebo-controlled multicenter Canadian trial. Canadian Exosurf Neonatal Study Group.
Topics: Air; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Lung Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1995 |
Double-blind, randomized trial of one versus three prophylactic doses of synthetic surfactant in 826 neonates weighing 700 to 1100 grams: effects on mortality rate. American Exosurf Neonatal Study Groups I and IIa.
Topics: Bronchopulmonary Dysplasia; Cause of Death; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Enterocolitis, Pseudomembranous; Fatty Alcohols; Follow-Up Studies; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature, Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn | 1995 |
Instillation rate effects of Exosurf on cerebral and cardiovascular haemodynamics in preterm neonates.
Topics: Blood Flow Velocity; Blood Pressure; Brain; Cerebrovascular Circulation; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Female; Heart; Hemodynamics; Humans; Infant, Newborn; Infant, Premature; Instillation, Drug; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1994 |
Improved oxygenation during synchronized intermittent mandatory ventilation in neonates with respiratory distress syndrome: a randomized, crossover study.
Topics: Carbon Dioxide; Combined Modality Therapy; Cross-Over Studies; Drug Combinations; Fatty Alcohols; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Intermittent Positive-Pressure Ventilation; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 1995 |
Partial liquid ventilation in premature lambs with respiratory distress syndrome: efficacy and compatibility with exogenous surfactant.
Topics: Animals; Animals, Newborn; Biological Products; Combined Modality Therapy; Drug Combinations; Emulsions; Fatty Alcohols; Fluorocarbons; Humans; Hydrocarbons, Brominated; Infant, Newborn; Oxygen; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Random Allocation; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Sheep | 1995 |
Pulmonary mechanics in ventilated preterm infants with respiratory distress syndrome after exogenous surfactant administration: a comparison between two surfactant preparations.
Topics: Airway Resistance; Biological Products; Combined Modality Therapy; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature, Diseases; Lung Compliance; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Mechanics; Time Factors | 1994 |
Exosurf rescue surfactant improves high ventilation-perfusion mismatch in respiratory distress syndrome.
Topics: Airway Resistance; Blood Gas Analysis; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Male; Oxygen Consumption; Phosphorylcholine; Polyethylene Glycols; Pulmonary Circulation; Pulmonary Gas Exchange; Pulmonary Surfactants; Regression Analysis; Respiration; Respiratory Distress Syndrome, Newborn; Time Factors | 1994 |
Safety and potential efficacy of an aerosolized surfactant in human sepsis-induced adult respiratory distress syndrome.
Topics: Adult; Aerosols; Aged; APACHE; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Female; Hemodynamics; Humans; Intubation; Male; Middle Aged; Phosphorylcholine; Pilot Projects; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Function Tests; Sepsis; Survival Analysis | 1994 |
Surfactant therapy in respiratory distress syndrome--the first local experience.
Topics: Cause of Death; Combined Modality Therapy; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Length of Stay; Male; Oxygen Inhalation Therapy; Phosphorylcholine; Pilot Projects; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Survival Rate; Treatment Outcome | 1994 |
OSIRIS trial.
Topics: Adrenal Cortex Hormones; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1993 |
OSIRIS trial.
Topics: Brain Diseases; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Ultrasonography | 1993 |
OSIRIS trial.
Topics: Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Humans; Infant Mortality; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1993 |
OSIRIS trial.
Topics: Diagnostic Errors; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radiography; Respiratory Distress Syndrome, Newborn | 1993 |
Static respiratory compliance in the newborn. III: Early changes after exogenous surfactant treatment.
Topics: Animals; Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Lung Compliance; Male; Oxygen; Partial Pressure; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Swine | 1994 |
Comparison of clinical responses to natural and synthetic surfactants.
Topics: Arteries; Biological Products; Cerebral Hemorrhage; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Oxygen; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn | 1993 |
Modified bovine surfactant (Survanta) versus a protein-free surfactant (Exosurf) in the treatment of respiratory distress syndrome in preterm infants: a pilot study.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Pilot Projects; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1994 |
Respiratory distress syndrome in New Zealand: evidence from the OSIRIS trial of exogenous surfactant (Exosurf).
Topics: Birth Weight; Cerebral Hemorrhage; Cohort Studies; Cost of Illness; Drug Combinations; Fatty Alcohols; Female; Hospital Mortality; Humans; Infant, Newborn; Infant, Premature; Male; New Zealand; Oxygen Inhalation Therapy; Phosphorylcholine; Polyethylene Glycols; Prenatal Care; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Steroids; Survival Rate; Ultrasonography | 1994 |
Cardiorespiratory and stress hormone responses during first dose surfactant administration in neonates with RDS.
Topics: Biological Products; Blood Pressure; Catecholamines; Drug Combinations; Fatty Alcohols; Hemodynamics; Humans; Infant, Newborn; Oxygen; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Sympathetic Nervous System | 1994 |
A multicenter randomized trial comparing two surfactants for the treatment of neonatal respiratory distress syndrome. National Institute of Child Health and Human Development Neonatal Research Network.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Mechanics; Treatment Outcome | 1993 |
Cost effects of surfactant therapy for neonatal respiratory distress syndrome.
Topics: Costs and Cost Analysis; Drug Combinations; Fatty Alcohols; Female; Hospital Costs; Hospital Mortality; Humans; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Regression Analysis; Respiratory Distress Syndrome, Newborn | 1993 |
The physiologic effects of surfactant treatment on gas exchange in newborn premature infants with hyaline membrane disease.
Topics: Biological Products; Birth Weight; Drug Combinations; Fatty Alcohols; Female; Gestational Age; Humans; Hyaline Membrane Disease; Hydrogen-Ion Concentration; Infant, Newborn; Infant, Premature; Male; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Function Tests | 1993 |
[Natural and synthetic surfactant in the treatment of neonatal respiratory distress syndrome].
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature, Diseases; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1994 |
Long-term pulmonary consequences of respiratory distress syndrome in preterm infants treated with exogenous surfactant.
Topics: Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Lung Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests; Treatment Outcome | 1993 |
A multicenter, randomized trial comparing synthetic surfactant with modified bovine surfactant extract in the treatment of neonatal respiratory distress syndrome. Vermont-Oxford Neonatal Network.
Topics: Biological Products; Chronic Disease; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Lung Diseases; Male; Oxygen Inhalation Therapy; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Risk | 1996 |
Aerosolized surfactant in adults with sepsis-induced acute respiratory distress syndrome. Exosurf Acute Respiratory Distress Syndrome Sepsis Study Group.
Topics: Administration, Inhalation; Aerosols; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Male; Middle Aged; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome; Sepsis; Survival Rate; Treatment Failure | 1996 |
Retinopathy of prematurity in a controlled trial of prophylactic surfactant treatment.
Topics: Drug Combinations; England; Fatty Alcohols; Female; Follow-Up Studies; Humans; Incidence; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retinopathy of Prematurity; Survival Analysis | 1996 |
Exogenous surfactant use in neonates.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1996 |
A multicenter randomized, masked comparison trial of natural versus synthetic surfactant for the treatment of respiratory distress syndrome.
Topics: Bronchopulmonary Dysplasia; Cross-Over Studies; Drug Combinations; Fatty Alcohols; Humans; Incidence; Infant, Newborn; Length of Stay; Linear Models; Phosphorylcholine; Pneumothorax; Polyethylene Glycols; Pulmonary Emphysema; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Survival Rate; Time Factors; Treatment Outcome | 1996 |
Factors affecting the neonatal response to artificial surfactant.
Topics: Administration, Inhalation; Analysis of Variance; Chi-Square Distribution; Drug Combinations; Evaluation Studies as Topic; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Oxygen Consumption; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration; Respiratory Distress Syndrome, Newborn; Survival Rate; Treatment Outcome | 1996 |
Respiratory mechanics before and after late artificial surfactant rescue.
Topics: Age Factors; Combined Modality Therapy; Drug Combinations; Fatty Alcohols; Female; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature, Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiration, Artificial; Respiratory Mechanics | 1995 |
Comparison of the changes in the a/A oxygen ratio after administration of two surfactants for the treatment of neonatal respiratory distress syndrome.
Topics: Algorithms; Biological Products; Blood Gas Analysis; Drug Combinations; Fatty Alcohols; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1997 |
A multicenter randomized masked comparison trial of synthetic surfactant versus calf lung surfactant extract in the prevention of neonatal respiratory distress syndrome.
Topics: Age Factors; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Data Interpretation, Statistical; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Linear Models; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Time Factors; Treatment Outcome | 1997 |
Hyaline membrane disease (HMD) therapy in Latin America: impact of exogenous surfactant administration on newborn survival, morbidity and use of resources.
Topics: Birth Weight; Drug Combinations; Fatty Alcohols; Female; Humans; Hyaline Membrane Disease; Infant Mortality; Infant, Newborn; Infant, Premature; Intensive Care, Neonatal; Latin America; Male; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Retrospective Studies | 1997 |
Effects of aerosolized surfactant in patients with stable chronic bronchitis: a prospective randomized controlled trial.
Topics: Administration, Intranasal; Aerosols; Aged; Bronchitis; Chronic Disease; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Humans; Male; Middle Aged; Mucociliary Clearance; Nebulizers and Vaporizers; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Function Tests; Sputum; Statistics, Nonparametric | 1997 |
Surfactant replacement therapy improves ventilation inhomogeneity in infants with respiratory distress syndrome.
Topics: Analysis of Variance; Biological Products; Breath Tests; Double-Blind Method; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Linear Models; Nitrogen; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Gas Exchange; Pulmonary Surfactants; Pulmonary Ventilation; Respiratory Distress Syndrome, Newborn | 1997 |
Collaborative trial of prenatal thyrotropin-releasing hormone and corticosteroids for prevention of respiratory distress syndrome. Collaborative Santiago Surfactant Group.
Topics: Adrenal Cortex Hormones; Adult; Betamethasone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Fetus; Humans; Incidence; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Maternal Welfare; Phosphorylcholine; Polyethylene Glycols; Pregnancy; Pregnancy Outcome; Prolactin; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Thyroid Hormones; Thyrotropin-Releasing Hormone | 1998 |
Changes in pulmonary artery pressure during the acute phase of respiratory distress syndrome treated with three different types of surfactant.
Topics: Acceleration; Biological Products; Birth Weight; Blood Pressure; Cardiac Output; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Inhalation; Oxygen; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pressure; Pulmonary Artery; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Time Factors; Ultrasonography, Doppler; Ventricular Function, Right | 1998 |
Randomized trial examining cerebral haemodynamics following artificial or animal surfactant.
Topics: Biological Products; Cerebral Arteries; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Hemodynamics; Humans; Infant, Newborn; Infant, Premature; Intermittent Positive-Pressure Ventilation; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Regional Blood Flow; Respiratory Distress Syndrome, Newborn; Statistics, Nonparametric | 1998 |
Tracheal aspirate surface tension in babies with hyaline membrane disease: effects of synthetic surfactant replacement.
Topics: Double-Blind Method; Drug Combinations; Exudates and Transudates; Fatty Alcohols; Female; Humans; Hyaline Membrane Disease; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Surface Tension; Trachea | 1998 |
Serial phospholipid analysis in preterm infants: comparison of Exosurf and Survanta.
Topics: Analysis of Variance; Biological Products; Chi-Square Distribution; Chromatography, Thin Layer; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 1999 |
Single dose surfactant rescue therapy in neonatal respiratory distress syndrome.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Lipids; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Survival Analysis | 1998 |
Comparative trial of artificial and natural surfactants in the treatment of respiratory distress syndrome of prematurity: experiences in a developing country.
Topics: Biological Products; Blood Gas Analysis; Developing Countries; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male; Oman; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Survival Rate; Treatment Outcome | 1999 |
Randomized trial comparing natural and synthetic surfactant: increased infection rate after natural surfactant?
Topics: Biological Products; C-Reactive Protein; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Leukopenia; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Risk; Sepsis; Thrombocytopenia | 2000 |
The effects of synthetic and natural surfactant on fluid balance in acute respiratory distress syndrome.
Topics: Biological Products; Birth Weight; Diuresis; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Infant, Newborn; Infant, Premature; London; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Time Factors; Treatment Outcome; Water-Electrolyte Balance | 2000 |
Surfactant replacement for ventilator-associated pneumonia: a preliminary report.
Topics: Adult; Aged; Analysis of Variance; Bronchoalveolar Lavage Fluid; Bronchoscopy; Double-Blind Method; Drug Combinations; Fatty Alcohols; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phosphorylcholine; Pneumonia, Bacterial; Polyethylene Glycols; Probability; Pulmonary Surfactants; Reference Values; Respiration, Artificial; Respiratory Function Tests; Sodium Chloride; Statistics, Nonparametric; Treatment Outcome | 2002 |
Comparative randomized study: administration of natural and synthetic surfactant to premature newborns with respiratory distress syndrome.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn | 2002 |
Postnatal changes in pulmonary mechanics and energetics of infants with respiratory distress syndrome following surfactant treatment.
Topics: Continuous Positive Airway Pressure; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Longitudinal Studies; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests; Retrospective Studies | 2005 |
114 other study(ies) available for dipalmitoylphosphatidylcholine, hexadecanol, tyloxapol drug combination and phosphorylcholine
| Article | Year |
|---|---|
[Exosurf-Neonatal: the synthetic surfactant. Introductory symposium, 20 June 1992].
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Effect of intra-amniotic administration of Exosurf in preterm rabbit fetuses.
Topics: Amnion; Animals; Animals, Newborn; Drug Combinations; Fatty Alcohols; Fetus; Gestational Age; Humans; Infant, Newborn; Injections; Lung; Organ Size; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Respiratory Distress Syndrome, Newborn | 1992 |
Perinatal pharmacology and cerebral blood flow.
Topics: Arteries; Blood Flow Velocity; Caffeine; Carbon Dioxide; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Indomethacin; Infant, Newborn; Partial Pressure; Phenobarbital; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1992 |
Lung mechanics and gas exchange in ventilated preterm infants during treatment of hyaline membrane disease with multiple doses of artificial surfactant (Exosurf)
Topics: Carbon Dioxide; Drug Combinations; Fatty Alcohols; Female; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Male; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Gas Exchange; Pulmonary Surfactants; Respiration, Artificial; Respiratory Mechanics | 1992 |
Synthetic surfactant (Exosurf) inhibits endotoxin-stimulated cytokine secretion by human alveolar macrophages.
Topics: Cytokines; Drug Combinations; Endotoxins; Fatty Alcohols; Humans; Macrophages; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants | 1992 |
Criteria for use of colfosceril (Exosurf) in neonates.
Topics: Apnea; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Newborn; Intubation, Intratracheal; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn | 1992 |
A controlled clinical comparison of four different surfactant preparations in surfactant-deficient preterm lambs.
Topics: Animals; Animals, Newborn; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Sheep | 1992 |
Prediction of the acute response to surfactant therapy by pulmonary function testing.
Topics: Airway Resistance; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Lung Compliance; Phosphorylcholine; Polyethylene Glycols; Predictive Value of Tests; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Respiratory Function Tests | 1992 |
On surfactant replacement therapy with Exosurf.
Topics: Clinical Trials as Topic; Drug Combinations; Fatty Alcohols; Humans; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1992 |
Surfactant replacement therapy: issues related to currently available preparations.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Maternal-Child Nursing; Monitoring, Physiologic; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1992 |
Importance of hydrophobic apoproteins as constituents of clinical exogenous surfactants.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adsorption; Albumins; Animals; Apoproteins; Biological Products; Cattle; Drug Combinations; Fatty Alcohols; In Vitro Techniques; Lung; Phosphorylcholine; Polyethylene Glycols; Proteolipids; Pulmonary Surfactants; Rats; Surface Tension; Surface-Active Agents | 1992 |
Comparing surfactant products.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Synthetic vs human surfactants in the treatment of respiratory distress syndrome: radiographic findings.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Emphysema; Pulmonary Surfactants; Radiography, Thoracic; Respiratory Distress Syndrome, Newborn | 1991 |
Colfosceril palmitate (Exosurf)--artificial surfactant for immature lungs.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1991 |
Effect of institutional differences on study of surfactant in two centers.
Topics: Bronchopulmonary Dysplasia; Drug Combinations; Fatty Alcohols; Hospitals; Humans; Infant, Low Birth Weight; Infant, Newborn; Multicenter Studies as Topic; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; United States | 1991 |
From the Food and Drug Administration.
Topics: Chronic Disease; Diet Fads; Dietary Fiber; Drug Combinations; Esophageal Stenosis; Fatty Alcohols; Fentanyl; Galactans; Humans; Infant, Low Birth Weight; Infant, Newborn; Mannans; Pain; Phosphorylcholine; Plant Gums; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; United States; United States Food and Drug Administration | 1990 |
Effects of aerosolized artificial surfactant on repeated oleic acid injury in sheep.
Topics: Aerosols; Animals; Drug Combinations; Fatty Alcohols; Lung Compliance; Oleic Acid; Oleic Acids; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Edema; Pulmonary Surfactants; Sheep | 1990 |
Lung function in prematurely delivered rabbits treated with a synthetic surfactant.
Topics: Animals; Drug Combinations; Fatty Alcohols; Infant, Newborn; Lung; Lung Compliance; Lung Volume Measurements; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Gas Exchange; Pulmonary Surfactants; Rabbits; Respiratory Distress Syndrome, Newborn | 1987 |
Effects of a protein-free, synthetic surfactant on survival and pulmonary function in preterm lambs.
Topics: Animals; Animals, Newborn; Drug Combinations; Fatty Alcohols; Fetal Organ Maturity; Humans; Infant, Newborn; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Sheep | 1985 |
Dose-response comparisons of five lung surfactant factor (LSF) preparations in an animal model of adult respiratory distress syndrome (ARDS).
Topics: Animals; Biological Products; Blood Gas Analysis; Cattle; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Fatty Alcohols; Feasibility Studies; Lipids; Male; Partial Pressure; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Alveoli; Pulmonary Gas Exchange; Pulmonary Surfactants; Pulmonary Wedge Pressure; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiratory Distress Syndrome; Trachea | 1995 |
Regulation of human alveolar macrophage inflammatory cytokines by tyloxapol: a component of the synthetic surfactant Exosurf.
Topics: Cells, Cultured; Cytokines; Down-Regulation; Drug Combinations; Fatty Alcohols; Humans; Macrophages, Alveolar; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; RNA, Messenger; Surface-Active Agents | 1995 |
Nebulized synthetic surfactant in reperfusion injury after single lung transplantation.
Topics: Adult; Aerosols; Drug Combinations; Fatty Alcohols; Female; Humans; Lung Diseases; Lung Transplantation; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radiography; Reperfusion Injury | 1995 |
Interaction of surfactant mixtures with reactive oxygen and nitrogen species.
Topics: Animals; Antioxidants; Biological Products; Drug Combinations; Fatty Alcohols; Formaldehyde; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Lung; Nitrates; Nitrogen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Reactive Oxygen Species; Surface Tension; Xanthine Oxidase | 1995 |
Artificial surfactant attenuates hyperoxic lung injury in primates. I. Physiology and biochemistry.
Topics: Animals; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Fatty Alcohols; Hemodynamics; Lung Diseases; Male; Oxygen; Papio; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Proteolipids; Pulmonary Edema; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Respiratory Mechanics | 1995 |
Artificial surfactant attenuates hyperoxic lung injury in primates. II. Morphometric analysis.
Topics: Aerosols; Animals; Blood Gas Analysis; Cell Division; Drug Combinations; Endothelium; Fatty Alcohols; Hemodynamics; Lung; Lung Diseases; Male; Microscopy, Electron; Oxygen; Papio; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants | 1995 |
Lysis of red blood cells and alveolar epithelial toxicity by therapeutic pulmonary surfactants.
Topics: Animals; Biological Products; Drug Combinations; Epithelial Cells; Epithelium; Fatty Alcohols; Hemolysis; Hemorrhage; Humans; In Vitro Techniques; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Male; Models, Biological; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Rats | 1995 |
Aerosolized surfactant in sepsis-induced adult respiratory distress syndrome.
Topics: Drug Combinations; Fatty Alcohols; Humans; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Sepsis | 1995 |
Changes in pulmonary artery pressure in infants with respiratory distress syndrome following treatment with Exosurf.
Topics: Acute Disease; Blood Pressure; Drug Combinations; Echocardiography, Doppler; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Artery; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1995 |
Surfactant therapy and high-frequency jet ventilation in the management of a piglet model of the meconium aspiration syndrome.
Topics: Animals; Animals, Newborn; Biological Products; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Combinations; Fatty Alcohols; High-Frequency Jet Ventilation; Humans; Infant, Newborn; Inflammation; Lung; Meconium Aspiration Syndrome; Oxygen; Partial Pressure; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Random Allocation; Suction; Swine; Trachea | 1994 |
Comparison of surface properties and physiological effects of a synthetic and a natural surfactant in preterm rabbits.
Topics: Animals; Biological Products; Drug Combinations; Epithelium; Fatty Alcohols; Lung; Lung Compliance; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Random Allocation; Surface Properties | 1994 |
Acute effects of synthetic surfactant replacement on pulmonary blood flow in neonatal respiratory distress syndrome.
Topics: Blood Flow Velocity; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Circulation; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Suction; Ultrasonography, Doppler | 1994 |
Outcome of infants with birth weights less than 1000 g with respiratory distress syndrome treated with high-frequency ventilation and surfactant replacement therapy.
Topics: Biological Products; Combined Modality Therapy; Drug Combinations; Fatty Alcohols; High-Frequency Ventilation; Humans; Infant, Low Birth Weight; Infant, Newborn; Logistic Models; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Treatment Outcome | 1995 |
Immunosuppressive properties of surfactant and plasma on alveolar macrophages.
Topics: Biological Products; Bronchoalveolar Lavage Fluid; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Fatty Alcohols; Female; Humans; Immune Tolerance; Interleukin-1; Lipopolysaccharides; Macrophages, Alveolar; Male; Phosphorylcholine; Plasma; Polyethylene Glycols; Protein Precursors; Pulmonary Surfactants; Receptors, Interleukin-1; Respiratory Distress Syndrome; Tumor Necrosis Factor-alpha | 1995 |
Artificial surfactant in the treatment of near drowning.
Topics: Child; Drug Combinations; Fatty Alcohols; Humans; Intubation, Intratracheal; Male; Near Drowning; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Surfactants; Resuscitation; Rewarming | 1993 |
Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study.
Topics: Cohort Studies; Drug Combinations; Ductus Arteriosus, Patent; Fatty Alcohols; Female; Hemorrhage; Humans; Infant, Newborn; Lung Diseases; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Retrospective Studies | 1994 |
The effect of three surfactant preparations on in vitro lymphocyte functions.
Topics: Adult; Biological Products; Cell Division; Cells, Cultured; Drug Combinations; Fatty Alcohols; Fetal Blood; Humans; Immunoglobulins; Lipids; Lymphocyte Activation; Lymphocytes; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1994 |
Effect of different surfactants on pulmonary group B streptococcal infection in premature rabbits.
Topics: Animals; Animals, Newborn; Biological Products; Cell Division; Drug Combinations; Fatty Alcohols; Lung Diseases; Macrophages, Alveolar; Models, Biological; Phagocytosis; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Streptococcal Infections; Streptococcus agalactiae | 1994 |
Lung gas volumes and expiratory time constant in immature newborn rabbits treated with natural or synthetic surfactant or detergents.
Topics: Animals; Animals, Newborn; Biological Products; Detergents; Drug Combinations; Fatty Alcohols; Fetal Organ Maturity; Lung; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Respiratory Function Tests | 1994 |
Pulmonary haemorrhage in low-birthweight babies.
Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Hyaline Membrane Disease; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1993 |
Pulmonary haemorrhage, surfactant, and low-birthweight babies.
Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Lung Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1993 |
Platelet-activating factor in surfactant preparations.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phospholipases A; Phospholipids; Phosphorylcholine; Platelet Activating Factor; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Trachea | 1993 |
Adverse experiences in an Exosurf treated group.
Topics: Case-Control Studies; Drug Combinations; Fatty Alcohols; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Treatment Outcome | 1994 |
Characterization of exosurf (surfactant)-mediated suppression of stimulated human alveolar macrophage cytokine responses.
Topics: Adult; Biological Products; Cytokines; Drug Combinations; Fatty Alcohols; Humans; Interleukin-1; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Macrophages, Alveolar; Nucleic Acid Hybridization; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; RNA, Messenger; Smoking; Tumor Necrosis Factor-alpha | 1994 |
Successful treatment of ARDS with two doses of synthetic surfactant.
Topics: Drug Combinations; Fatty Alcohols; Humans; Male; Middle Aged; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome | 1994 |
Aerosol characteristics of 99mTc-pentetic acid (DTPA) and synthetic surfactant (Exosurf).
Topics: Aerosols; Chromatography, Thin Layer; Drug Combinations; Fatty Alcohols; Feasibility Studies; Humans; Lung; Models, Structural; Nebulizers and Vaporizers; Particle Size; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radionuclide Imaging; Technetium Tc 99m Pentetate; Ventilators, Mechanical | 1994 |
[Natural or synthetic surfactant in the treatment of neonatal respiratory distress syndrome].
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1994 |
Reduction of the surface-tension-lowering ability of surfactant after exposure to hypochlorous acid.
Topics: Amniotic Fluid; Ascorbic Acid; Biological Products; Drug Combinations; Fatty Alcohols; Glutathione; Humans; Hypochlorous Acid; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface Tension; Surface-Active Agents; Time Factors | 1993 |
Exosurf treatment following wood smoke inhalation.
Topics: Airway Resistance; Animals; Carbon Dioxide; Drug Combinations; Extravascular Lung Water; Fatty Alcohols; Instillation, Drug; Lung; Lung Compliance; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Edema; Pulmonary Surfactants; Rabbits; Smoke Inhalation Injury; Surface Tension; Wood | 1993 |
Surfactant replacement therapy in neonates less than 32 weeks gestation: effect on neonatal intensive care resource utilization.
Topics: Case-Control Studies; Drug Combinations; Fatty Alcohols; Hospital Costs; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; New South Wales; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial | 1993 |
Commentary on Surface tension of therapeutic surfactants as evaluated by standard methods and criteria--Scarpelli, David, Cordova, and Mautone.
Topics: Animals; Biological Products; Drug Combinations; Fatty Alcohols; Humans; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface Tension | 1993 |
Mechanisms of bilirubin toxicity.
Topics: Animals; Bilirubin; Biological Products; Brain; Dose-Response Relationship, Drug; Drug Combinations; Fatty Alcohols; Hyperbilirubinemia; Male; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Surface Tension; Tyrosine | 1995 |
Screening for retinopathy of prematurity after surfactant treatment.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Mass Screening; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Retinopathy of Prematurity; Switzerland; Treatment Outcome | 1995 |
Acute blood pressure response to surfactant administration.
Topics: Blood Flow Velocity; Blood Pressure; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1995 |
Efficacy of surfactant therapy in infants managed with CPAP.
Topics: Combined Modality Therapy; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Male; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 1995 |
Exogenous surfactants in a piglet model of acute respiratory distress syndrome.
Topics: Animals; Animals, Newborn; Biological Products; Bronchoalveolar Lavage Fluid; Drug Combinations; Fatty Alcohols; Functional Residual Capacity; Intercellular Signaling Peptides and Proteins; Lung; Peptides; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Respiratory Mechanics; Swine | 1996 |
The acute respiratory distress syndrome.
Topics: Aerosols; Drug Combinations; Fatty Alcohols; Humans; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Treatment Failure | 1996 |
Therapy for lung failure using nitric oxide inhalation and surfactant replacement.
Topics: Adult; Drug Combinations; Fatty Alcohols; Humans; Hypoxia; Lung Transplantation; Male; Nitric Oxide; Phosphorylcholine; Polyethylene Glycols; Postoperative Complications; Pulmonary Surfactants; Reperfusion Injury; Respiratory Insufficiency | 1996 |
Physiologic response and lung distribution of lavage versus bolus Exosurf in piglets with acute lung injury.
Topics: Acute Disease; Animals; Animals, Newborn; Drug Combinations; Fatty Alcohols; Female; Injections; Lung; Lung Injury; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Swine; Therapeutic Irrigation; Time Factors; Tissue Distribution | 1996 |
[Outcome of blood gas parameters during the first 24 years after Exosurf administration].
Topics: Analysis of Variance; Blood Gas Analysis; Cohort Studies; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Time Factors | 1996 |
Surfactant downregulates synthesis of DNA and inflammatory mediators in normal human lung fibroblasts.
Topics: Antioxidants; Biological Products; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Drug Combinations; Fatty Alcohols; Fibroblasts; Humans; Inflammation Mediators; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Reference Values | 1996 |
Changes in pulmonary artery pressure in infants with respiratory distress syndrome after treatment with Exosurf.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Pulmonary Wedge Pressure; Respiratory Distress Syndrome, Newborn | 1996 |
Inactivation of surfactant in rat lungs.
Topics: Animals; Biological Products; Disease Models, Animal; Drug Combinations; Fatty Alcohols; Female; Humans; Lung; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Surface Tension; Surface-Active Agents; Swine; Temperature; Time Factors | 1996 |
Differences in immediate and short-term outcome of premature neonates treated with two types of exogenous surfactant preparation.
Topics: Biological Products; Bronchopulmonary Dysplasia; Cerebral Hemorrhage; Drug Combinations; Ductus Arteriosus, Patent; Fatty Alcohols; Female; Hemodynamics; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Male; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Pulmonary Ventilation; Remission Induction; Respiration, Artificial; Retrospective Studies; Survival Rate; Time Factors; Treatment Outcome; Ventilation-Perfusion Ratio | 1995 |
Effects of different surfactant preparations on bacterial growth in vitro.
Topics: Adult; Bacteria; Biological Products; Cell Division; Drug Combinations; Fatty Alcohols; Humans; Infant; Lipids; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Trachea | 1996 |
Quantitation of the alveolar distribution of surfactant mixtures in normal and injured lungs.
Topics: Animals; Drug Combinations; Fatty Alcohols; Flow Cytometry; Fluorescent Dyes; Hyperoxia; Lung; Male; Microscopy, Fluorescence; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits | 1996 |
The surface properties of chemically synthesized peptides analogous to human pulmonary surfactant protein SP-C.
Topics: Amino Acid Sequence; Animals; Bacterial Proteins; Cattle; Drug Combinations; Fatty Alcohols; Humans; Lipopeptides; Lung; Lung Volume Measurements; Molecular Sequence Data; Peptides, Cyclic; Phosphorylcholine; Polyethylene Glycols; Proteolipids; Pulmonary Surfactants; Rabbits; Surface Properties | 1996 |
Susceptibility of exogenous surfactant to phospholipase A2 degradation.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Acetylation; Animals; Biological Products; Cattle; Chemistry, Pharmaceutical; Drug Combinations; Fatty Alcohols; Hydrogen-Ion Concentration; Lysophosphatidylcholines; Phospholipases A; Phospholipases A2; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1996 |
Influence of bilirubin on surface tension properties of lung surfactant.
Topics: Bilirubin; Biological Products; Drug Combinations; Fatty Alcohols; Humans; In Vitro Techniques; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface Tension | 1996 |
Exogenous surfactant decreases oxygenation in Escherichia coli endotoxin-treated neonatal piglets.
Topics: Animals; Animals, Newborn; Biological Products; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Combinations; Endotoxins; Escherichia coli; Fatty Alcohols; Female; Lung; Lung Compliance; Male; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Pulmonary Ventilation; Respiratory Distress Syndrome; Swine; Time Factors | 1996 |
Surfactant inhibits cationic liposome-mediated gene transfer.
Topics: Animals; Biological Products; Cations; Cattle; Cell Line; Chloramphenicol O-Acetyltransferase; Drug Combinations; Fatty Alcohols; Gene Transfer Techniques; Liposomes; Phosphorylcholine; Plasmids; Polyethylene Glycols; Pulmonary Surfactants; Rats; Transfection | 1997 |
Costs and outcomes associated with colfosceril versus beractant for the treatment of neonatal respiratory distress syndrome.
Topics: Biological Products; Drug Combinations; Drug Costs; Fatty Alcohols; Humans; Infant, Newborn; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 1997 |
Exosurf enhances adenovirus-mediated gene transfer to alveolar type II cells.
Topics: Adenocarcinoma; Adenoviridae; Animals; Cells, Cultured; Drug Combinations; Epithelial Cells; Fatty Alcohols; Gene Transfer Techniques; Genes, Reporter; Humans; Luciferases; Lung Neoplasms; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Transfection; Tumor Cells, Cultured | 1997 |
Repeated doses of the perfluorocarbon FC-100 improve lung function of preterm lambs.
Topics: Animals; Animals, Newborn; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Female; Fluorocarbons; Gestational Age; Intubation, Intratracheal; Lung; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Function Tests; Sheep | 1997 |
Effect of inhaled surfactant on pulmonary deposition and clearance of technetium-99m-DTPA radioaerosol.
Topics: Administration, Inhalation; Aerosols; Animals; Dogs; Drug Combinations; Fatty Alcohols; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Pentetate; Time Factors | 1998 |
Nebulisation of surfactants in an animal model of neonatal respiratory distress.
Topics: Aerosols; Animals; Biological Products; Carbon Dioxide; Disease Models, Animal; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Lung; Nebulizers and Vaporizers; Oxygen; Partial Pressure; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Respiratory Distress Syndrome, Newborn | 1998 |
Hyaluronan production in vitro by fetal lung fibroblasts and epithelial cells exposed to surfactants of N-acetylcysteine.
Topics: Acetylcysteine; Animals; Biological Products; Cats; Cell Line; Drug Combinations; Epithelial Cells; Fatty Alcohols; Fibroblasts; Humans; Hyaluronic Acid; Lung; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1997 |
Lavage administration of dilute surfactants after acute lung injury in neonatal piglets.
Topics: Animals; Animals, Newborn; Bronchoalveolar Lavage; Disease Models, Animal; Drug Combinations; Fatty Alcohols; Intercellular Signaling Peptides and Proteins; Lung Diseases; Peptides; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Swine | 1998 |
Pathology of arrested acinar development in postsurfactant bronchopulmonary dysplasia.
Topics: Biological Products; Body Weight; Bronchopulmonary Dysplasia; Drug Combinations; Fatty Alcohols; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Organ Size; Phosphorylcholine; Polyethylene Glycols; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pulmonary Alveoli; Pulmonary Fibrosis; Pulmonary Surfactants; Retrospective Studies | 1998 |
[The effect of surfactant therapy on the oxygen treatment of premature infants with HMD].
Topics: Analysis of Variance; Biological Products; Combined Modality Therapy; Drug Combinations; Drug Evaluation; Fatty Alcohols; Gestational Age; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Oxygen Inhalation Therapy; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Retrospective Studies | 1998 |
New-born infants with severe hyaline membrane disease: radiological evaluation during high frequency oscillatory versus conventional ventilation.
Topics: Bronchopulmonary Dysplasia; Case-Control Studies; Drug Combinations; Fatty Alcohols; Female; High-Frequency Ventilation; Humans; Hyaline Membrane Disease; Infant, Newborn; Lung; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radiography; Respiration, Artificial; Survival Rate; Treatment Outcome | 1998 |
The effect of synthetic surfactant Exosurf on gene transfer in mouse lung in vivo.
Topics: Administration, Topical; Analysis of Variance; Animals; Chloramphenicol O-Acetyltransferase; Drug Combinations; Fatty Alcohols; Gene Expression; Genetic Therapy; Luciferases; Lung; Mice; Mice, Inbred BALB C; Phosphorylcholine; Polyethylene Glycols; Polymerase Chain Reaction; Pulmonary Surfactants; Transfection | 1998 |
Comparison of respiratory function and fluid balance in very low birthweight infants given artificial or natural surfactant or no surfactant treatment.
Topics: Biological Products; Diuresis; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Pulmonary Surfactants; Respiration, Artificial; Respiratory Physiological Phenomena; Water-Electrolyte Balance | 1998 |
The instillated surfactant in the treatment of sepsis-induced ARDS: case report.
Topics: Bronchi; Drug Combinations; Fatty Alcohols; Humans; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome; Sepsis | 1999 |
Surfactant administration in severe hypoxic respiratory failure due to respiratory syncytial virus.
Topics: Drug Combinations; Fatty Alcohols; Female; Humans; Infant; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiration, Artificial; Respiratory Syncytial Virus Infections; Treatment Outcome; Ventilators, Mechanical | 1999 |
Estimation of pulmonary deposition of aerosol using gamma scintigraphy.
Topics: Aerosols; Albuterol; Animals; Biological Products; Bronchodilator Agents; Drug Combinations; Fatty Alcohols; Gamma Cameras; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Scintillation Counting; Sodium Pertechnetate Tc 99m; Technetium Tc 99m Aggregated Albumin | 1999 |
Seizures after inadvertent umbilical venous infusion of synthetic surfactant (Exosurf): cause or coincidence?
Topics: Drug Combinations; Electroencephalography; Fatty Alcohols; Follow-Up Studies; Humans; Hyaline Membrane Disease; Infant, Newborn; Infusions, Intravenous; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Radiography; Seizures; Umbilical Veins | 1999 |
An in vitro comparison of the mucoactive properties of guaifenesin, iodinated glycerol, surfactant, and albuterol.
Topics: Adult; Albuterol; Animals; Drug Combinations; Expectorants; Fatty Alcohols; Glycerol; Guaifenesin; Humans; Mucociliary Clearance; Mucus; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Ranidae; Sputum | 1999 |
Surfactant replacement in reperfusion injury after clinical lung transplantation.
Topics: Adult; Drug Combinations; Fatty Alcohols; Female; Heart-Lung Transplantation; Humans; Lung; Lung Transplantation; Male; Middle Aged; Phosphorylcholine; Polyethylene Glycols; Postoperative Period; Pulmonary Surfactants; Reperfusion Injury; Surface-Active Agents; Treatment Outcome | 1999 |
Enhancement of dendrimer-mediated transfection using synthetic lung surfactant exosurf neonatal in vitro.
Topics: Animals; Bronchi; Cell Membrane Permeability; Drug Combinations; Endosomes; Endothelium, Vascular; Fatty Alcohols; Gene Expression; Gene Transfer Techniques; Green Fluorescent Proteins; Humans; In Situ Hybridization; Jurkat Cells; Luciferases; Luminescent Proteins; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface-Active Agents; Swine; Transfection | 1999 |
Safety of synthetic surfactant use before preterm newborn transport.
Topics: Consumer Product Safety; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Intensive Care, Neonatal; Male; Patient Transfer; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Retrospective Studies; Transportation of Patients; Treatment Outcome; Victoria | 1999 |
Dexamethasone enhances the activity of rSP-C surfactant but not of exosurf in a rat model of the acute lung injury.
Topics: Animals; Cell Movement; Dexamethasone; Drug Combinations; Drug Synergism; Fatty Alcohols; Lung; Male; Neutrophils; Oxygen; Phosphorylcholine; Polyethylene Glycols; Positive-Pressure Respiration; Proteolipids; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Respiratory Distress Syndrome | 1999 |
[Surface-active properties of phosphatidylcholines--basis for surfactant replacement therapy].
Topics: Drug Combinations; Fatty Alcohols; Phosphatidylcholines; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface Properties; Surface-Active Agents; Water | 2000 |
First intention high-frequency oscillation with early lung volume optimization improves pulmonary outcome in very low birth weight infants with respiratory distress syndrome.
Topics: Drug Combinations; Fatty Alcohols; Female; High-Frequency Ventilation; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Infant, Very Low Birth Weight; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 2000 |
Randomized trial comparing natural and synthetic surfactant: increased infection rate after natural surfactant?
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Infant, Premature; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome, Newborn; Risk; Sepsis | 2000 |
Modulation of nitric oxide production by lung surfactant in alveolar macrophages.
Topics: Animals; Cell Line; Drug Combinations; Escherichia coli; Fatty Alcohols; Glycoproteins; Humans; Interferon-gamma; Kinetics; Lipopolysaccharides; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; omega-N-Methylarginine; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Proteolipids; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2000 |
Influence of modified natural or synthetic surfactant preparations on growth of bacteria causing infections in the neonatal period.
Topics: Biological Products; Drug Combinations; Escherichia coli; Fatty Alcohols; Humans; Infant, Newborn; Lipids; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Staphylococcus aureus; Streptococcus agalactiae | 2000 |
Alveolar metabolism of natural vs. synthetic surfactants in preterm newborn rabbits.
Topics: Animals; Animals, Newborn; Biological Products; Drug Combinations; Fatty Alcohols; Fetus; Gestational Age; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Rabbits; Therapeutic Irrigation; Time Factors | 2001 |
[Surfactant therapy in newborns with hyaline membrane disease].
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Hyaline Membrane Disease; Infant, Low Birth Weight; Infant, Newborn; Infant, Very Low Birth Weight; Intermittent Positive-Pressure Ventilation; Oxygen Inhalation Therapy; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Retrospective Studies | 2000 |
Early retardation of 99mTc-DTPA radioaerosol transalveolar clearance in irradiated canine lung.
Topics: Administration, Inhalation; Aerosols; Animals; Dogs; Drug Combinations; Fatty Alcohols; Lipids; Lung; Phosphorylcholine; Polyethylene Glycols; Pulmonary Alveoli; Pulmonary Surfactants; Radiation Dosage; Radiation Injuries, Experimental; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Pentetate | 2001 |
Scoring of surface parameters of physiological relevance to surfactant therapy in respiratory distress syndrome.
Topics: Drug Combinations; Fatty Alcohols; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome; Rheology; Surface Properties; Thermodynamics | 2001 |
Comparison of in vitro surface properties of clove oil-phospholipid suspensions with those of ALEC, Exosurf and Survanta.
Topics: Adsorption; Biological Products; Drug Combinations; Eugenol; Fatty Alcohols; Humans; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Surface Properties | 2001 |
Surfactant therapy for hyaline membrane disease: the Chandigarh experience.
Topics: Biological Products; Drug Combinations; Fatty Alcohols; Female; Humans; Hyaline Membrane Disease; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 2001 |
Current surfactant use in premature infants.
Topics: Drug Combinations; Fatty Alcohols; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Treatment Outcome | 2001 |
Bulk shear viscosities of endogenous and exogenous lung surfactants.
Topics: Animals; Biological Products; Calcium; Cattle; Drug Combinations; Fatty Alcohols; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Sodium Chloride; Stress, Mechanical; Temperature; Viscosity | 2002 |
Decreased surface tension of upper airway mucosal lining liquid increases upper airway patency in anaesthetised rabbits.
Topics: Animals; Body Fluids; Drug Combinations; Fatty Alcohols; Male; Pharynx; Phosphorylcholine; Polyethylene Glycols; Pressure; Pulmonary Surfactants; Pulmonary Ventilation; Rabbits; Respiration, Artificial; Respiratory Mucosa; Sodium Chloride; Surface Tension; Tracheotomy | 2003 |
Effect of exogenous surfactant on the development of surfactant synthesis in premature rabbit lung.
Topics: Animals; Biological Products; Carbon Radioisotopes; Choline; Drug Combinations; Fatty Alcohols; Female; Gene Expression Regulation, Developmental; Gestational Age; Glycerol; Lung; Organ Culture Techniques; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pregnancy; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein B; Pulmonary Surfactant-Associated Protein C; Pulmonary Surfactant-Associated Proteins; Pulmonary Surfactants; Rabbits; Tritium | 2003 |
Surfactant protein profile of pulmonary surfactant in premature infants.
Topics: Blotting, Western; Drug Combinations; Fatty Alcohols; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Reference Values; Respiratory Distress Syndrome; Trachea | 2003 |
Respiratory distress syndrome in VLBW infants: changes in management and outcomes observed by the NICHD Neonatal Research Network.
Topics: Adrenal Cortex Hormones; Drug Combinations; Fatty Alcohols; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; National Institutes of Health (U.S.); Oxygen; Phosphorylcholine; Polyethylene Glycols; Pregnancy; Pulmonary Surfactants; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Treatment Outcome; United States | 2003 |
An observational study of surfactant treatment in infants of 23-30 weeks' gestation: comparison of prophylaxis and early rescue.
Topics: Biological Products; Drug Administration Schedule; Drug Combinations; Fatty Alcohols; Gestational Age; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Italy; Lipids; Oxygen Inhalation Therapy; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Time Factors; Treatment Outcome | 2003 |
Effect of fluidizing agents on paclitaxel penetration in cervical cancerous monolayer membranes.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Membrane Permeability; Drug Combinations; Fatty Alcohols; Female; Fluoresceins; Fluorescent Dyes; Humans; In Vitro Techniques; Liposomes; Membrane Fluidity; Membranes, Artificial; Models, Biological; Paclitaxel; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Surface-Active Agents; Uterine Cervical Neoplasms | 2007 |
[Biophysical models in investigations of exogenous surfactant activities on the surface tension and their theurapeutic effectiveness].
Topics: Animals; Biological Products; Biophysical Phenomena; Biophysics; Drug Combinations; Fatty Alcohols; Humans; Infant, Newborn; Lipids; Models, Biological; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn; Surface Tension | 2007 |
Immunosuppressive properties of surfactant in alveolar macrophage NR8383.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Biological Products; Cell Line; Drug Combinations; Fatty Alcohols; Humans; Immunosuppressive Agents; Interleukin-1beta; Macrophages, Alveolar; Nitric Oxide; Nitric Oxide Synthase Type II; Phospholipids; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactant-Associated Protein A; Pulmonary Surfactant-Associated Protein D; Pulmonary Surfactants; Rats; Respiratory Burst; Tumor Necrosis Factor-alpha | 2008 |
Indomethacin pharmacodynamics are altered by surfactant: a possible challenge to current indomethacin dosing guidelines created before surfactant availability.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Availability; Biological Products; Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Ductus Arteriosus, Patent; Echocardiography; Echocardiography, Doppler, Color; Fatty Alcohols; Guideline Adherence; Humans; Indomethacin; Infant, Newborn; Intensive Care Units, Neonatal; Kidney; Metabolic Clearance Rate; Phosphorylcholine; Polyethylene Glycols; Prospective Studies; Pulmonary Surfactants; Respiratory Distress Syndrome, Newborn | 2010 |
The effect of a peptide-containing synthetic lung surfactant on gas exchange and lung mechanics in a rabbit model of surfactant depletion.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Calcium; Disease Models, Animal; Drug Combinations; Fatty Alcohols; Oxygen; Phosphorylcholine; Polyethylene Glycols; Pulmonary Gas Exchange; Pulmonary Surfactants; Rabbits; Respiratory Dead Space; Respiratory Mechanics; Time Factors | 2013 |