dioxirane has been researched along with metaperiodate* in 1 studies
1 other study(ies) available for dioxirane and metaperiodate
| Article | Year |
|---|---|
Oxidation of cysteine to cysteic acid in proteins by peroxyacids, as monitored by immobilized pH gradients.
It has often been debated whether the presence of persulfate in a polyacrylamide gel could lead to the oxidation of cysteine (Cys) in proteins to cysteic acid. In fact, direct incubation of bovine serum albumin (BSA) with peroxodisulfate and periodate barely alters the isoelectric point (pI) and does not produce any cysteic acid. In contrast, caroate (peroxomonosulfate) and perphthalate strongly lower the pI of BSA. In the former case it as demonstrated that 4-Cys (of a total of 35) were converted into cysteic acid. Perphthalate was found to be, by far, the strongest oxidant: 15 (of 35) Cys residues were oxidized to cysteic acid and all methionine groups were destroyed. Topics: Ammonium Sulfate; Cysteic Acid; Cysteine; Epoxy Compounds; Hydrogen-Ion Concentration; Methionine; Oxidation-Reduction; Periodic Acid; Phthalic Acids; Proteins; Serum Albumin, Bovine; Sulfuric Acids | 1991 |