dioxetanone has been researched along with hydrazine* in 1 studies
1 other study(ies) available for dioxetanone and hydrazine
| Article | Year |
|---|---|
A novel chemiluminescent probe for hydrazine detection in water and HeLa cells.
Hydrazine is a substance harmful to humans and the environment, necessitating the development of a sensitive and specific detection method. Herein, a novel chemiluminescent probe based on Schaap's adamantylidene-dioxetane (CL-HZ) for detecting hydrazine was synthesized and evaluated. The probe was activated by the removal of a protecting group to form free phenoxy-dioxetane, when treated with hydrazine. It then showed a noticeable and sustainable fluorescent response without excitation, with intensity increasing 51-fold in the presence of hydrazine. CL-HZ can be used in 96-well high-throughput assays for analysis of hydrazine in polluted water samples and was successfully applied for the detection of hydrazine in living cells. Topics: Adamantane; Fluorescent Dyes; HeLa Cells; Heterocyclic Compounds, 1-Ring; Humans; Hydrazines; Luminescent Measurements; Molecular Structure; Optical Imaging; Water Pollutants, Chemical | 2019 |