diosgenone has been researched along with 17-alpha-hydroxyprogesterone in 1 studies
*17-alpha-Hydroxyprogesterone: A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. [MeSH]
*17-alpha-Hydroxyprogesterone: A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. [MeSH]
| Studies (diosgenone) | Trials (diosgenone) | Recent Studies (post-2010) (diosgenone) | Studies (17-alpha-hydroxyprogesterone) | Trials (17-alpha-hydroxyprogesterone) | Recent Studies (post-2010) (17-alpha-hydroxyprogesterone) |
|---|---|---|---|---|---|
| 11 | 0 | 4 | 2,148 | 145 | 434 |
| Protein | Taxonomy | diosgenone (IC50) | 17-alpha-hydroxyprogesterone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Homo sapiens (human) | 0.051 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.051 | |
| Adenosine receptor A3 | Homo sapiens (human) | 4.73 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.3 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.739 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 4.73 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.051 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.051 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.051 | |
| Mitogen-activated protein kinase 3 | Homo sapiens (human) | 3.157 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 4.73 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 6.905 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blair, S; Cruz, V; Echeverri, F; Escobar, G; Notario, R; Pabón, A; Vargas, E | 1 |
1 review(s) available for diosgenone and 17-alpha-hydroxyprogesterone
| Article | Year |
|---|---|
Diosgenone synthesis, anti-malarial activity and QSAR of analogues of this natural product.
Topics: 17-alpha-Hydroxyprogesterone; Animals; Antimalarials; Cell Survival; Drug Evaluation, Preclinical; Drug Resistance; Hep G2 Cells; Humans; Inhibitory Concentration 50; Malaria; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Parasitemia; Plasmodium berghei; Plasmodium falciparum; Quantitative Structure-Activity Relationship; Spiro Compounds; Triterpenes | 2013 |