diosgenin has been researched along with methotrexate in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huo, X; Liu, K; Liu, Q; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C; Wang, L; Yang, X; Zhen, Y | 1 |
| Ban, JS; Cai, B; Chun, C; Im, YJ; Lee, KK; Liao, A; Yang, HS | 1 |
| Gao, M; Li, Y; Peng, JY; Qi, Y; Sun, P; Xu, LN; Yin, LH | 1 |
| Akhtar, MF; Javed, M; Saleem, A | 1 |
4 other study(ies) available for diosgenin and methotrexate
| Article | Year |
|---|---|
Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Drug Resistance, Neoplasm; Enterocytes; Genes, Reporter; Humans; I-kappa B Proteins; Intestinal Absorption; Intestine, Small; Male; Methotrexate; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transfection | 2014 |
Design, synthesis of methotrexate-diosgenin conjugates and biological evaluation of their effect on methotrexate transport-resistant cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diosgenin; Drug Resistance, Neoplasm; Humans; Methotrexate | 2016 |
Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress.
Topics: Animals; Diosgenin; Kelch-Like ECH-Associated Protein 1; Kidney; Liver; Methotrexate; Mice; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Rats | 2021 |
Diosgenin, a steroidal sapogenin, arrests arthritis through modulation of inflammatory cytokines and oxidative stress biomarkers in Wistar rats.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers; Carrageenan; Cytokines; Diosgenin; Edema; Humans; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Sapogenins | 2023 |