Page last updated: 2024-08-26

diosgenin and methotrexate

diosgenin has been researched along with methotrexate in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Huo, X; Liu, K; Liu, Q; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C; Wang, L; Yang, X; Zhen, Y1
Ban, JS; Cai, B; Chun, C; Im, YJ; Lee, KK; Liao, A; Yang, HS1
Gao, M; Li, Y; Peng, JY; Qi, Y; Sun, P; Xu, LN; Yin, LH1
Akhtar, MF; Javed, M; Saleem, A1

Other Studies

4 other study(ies) available for diosgenin and methotrexate

ArticleYear
Dioscin enhances methotrexate absorption by down-regulating MDR1 in vitro and in vivo.
    Toxicology and applied pharmacology, 2014, Jun-01, Volume: 277, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cell Survival; Diosgenin; Dose-Response Relationship, Drug; Down-Regulation; Drug Interactions; Drug Resistance, Neoplasm; Enterocytes; Genes, Reporter; Humans; I-kappa B Proteins; Intestinal Absorption; Intestine, Small; Male; Methotrexate; NF-kappa B; NF-KappaB Inhibitor alpha; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors; Transfection

2014
Design, synthesis of methotrexate-diosgenin conjugates and biological evaluation of their effect on methotrexate transport-resistant cells.
    Steroids, 2016, Volume: 116

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Diosgenin; Drug Resistance, Neoplasm; Humans; Methotrexate

2016
Dioscin ameliorates methotrexate-induced liver and kidney damages via adjusting miRNA-145-5p-mediated oxidative stress.
    Free radical biology & medicine, 2021, Volume: 169

    Topics: Animals; Diosgenin; Kelch-Like ECH-Associated Protein 1; Kidney; Liver; Methotrexate; Mice; MicroRNAs; NF-E2-Related Factor 2; Oxidative Stress; Rats

2021
Diosgenin, a steroidal sapogenin, arrests arthritis through modulation of inflammatory cytokines and oxidative stress biomarkers in Wistar rats.
    Inflammopharmacology, 2023, Volume: 31, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Biomarkers; Carrageenan; Cytokines; Diosgenin; Edema; Humans; Methotrexate; Oxidative Stress; Rats; Rats, Wistar; Sapogenins

2023