Compounds > dioscin
Page last updated: 2024-09-03

dioscin and paclitaxel

dioscin has been researched along with paclitaxel in 3 studies

Compound Research Comparison

Studies
(dioscin)		Trials
(dioscin)		Recent Studies (post-2010)
(dioscin)		Studies
(paclitaxel)		Trials
(paclitaxel)		Recent Studies (post-2010) (paclitaxel)
250020031,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomydioscin (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Chai, H; Cordell, GA; Farnsworth, NR; Hollingshead, MG; Kardono, LB; Kinghorn, AD; Lantvit, D; Lee, IS; Mayo, JG; Mi, Q; Ngassapa, O; Peraza-Sánchez, S; Pezzuto, JM; Reyes-Lim, E; Riswan, S; Zhao, W1
Farnsworth, NR; Kinghorn, AD; Mi, Q; Pezzuto, JM; Swanson, SM; Wani, MC1
Chen, HC; Dai, Z; Liu, H; Liu, HY; Liu, YP; Luo, XD; Wang, B; Yan, H; Yang, D; Zhao, LX; Zhao, XD; Zhao, YL; Zhu, PF; Zhu, YY1

Reviews

1 review(s) available for dioscin and paclitaxel

ArticleYear
Use of the in vivo hollow fiber assay in natural products anticancer drug discovery.
    Journal of natural products, 2009, Mar-27, Volume: 72, Issue:3

    Topics: Antineoplastic Agents; Drug Discovery; Drug Screening Assays, Antitumor; Models, Biological; Molecular Structure

2009

Other Studies

2 other study(ies) available for dioscin and paclitaxel

ArticleYear
Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.
    Journal of natural products, 2002, Volume: 65, Issue:6

    Topics: Animals; Biological Factors; Colonic Neoplasms; Diosgenin; Disease Models, Animal; Diterpenes; Drug Screening Assays, Antitumor; Female; Heterocyclic Compounds, 3-Ring; HL-60 Cells; Humans; Inhibitory Concentration 50; KB Cells; Leukemia P388; Male; Melanoma; Mice; Molecular Structure; Naphthoquinones; Ovarian Neoplasms; Paclitaxel; Polymers; Prostatic Neoplasms; Triterpenes; Tumor Cells, Cultured

2002
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.
    European journal of medicinal chemistry, 2021, Jan-15, Volume: 210

    Topics: Antineoplastic Agents; Apoptosis; Biological Products; Brain Neoplasms; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Glioblastoma; Goosecoid Protein; Humans; Molecular Structure; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured

2021