dioscin has been researched along with beta-escin in 36 studies
| Studies (dioscin) | Trials (dioscin) | Recent Studies (post-2010) (dioscin) | Studies (beta-escin) | Trials (beta-escin) | Recent Studies (post-2010) (beta-escin) |
|---|---|---|---|---|---|
| 250 | 0 | 200 | 14,137 | 211 | 6,278 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.56) | 18.7374 |
| 1990's | 2 (5.56) | 18.2507 |
| 2000's | 16 (44.44) | 29.6817 |
| 2010's | 15 (41.67) | 24.3611 |
| 2020's | 1 (2.78) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, A; Hu, K; Iwasaki, S; Kobayashi, H; Yao, X | 1 |
| Deng, S; Han, X; Hui, Y; Yu, B; Yu, H | 1 |
| Ju, Y; Li, X; Liu, M; Wang, Z; Zhang, H; Zhou, J | 1 |
| Garegg, PJ; Gybäck, H; Lahmann, M; Oscarson, S; Suhr, R; Thiem, J | 1 |
| Han, X; Li, M; Yu, B | 1 |
| Hou, SJ; Lei, PS; Liang, XT; Shi, Y; Zou, CC | 1 |
| Sun, W; Tu, G; Zhang, Y | 1 |
| Cai, B; Cui, CB; Liu, HW; Wang, SL; Wu, CF; Yao, XS | 1 |
| KAWASAKI, T; TSUKAMOTO, T; YAMAUCHI, T | 1 |
| KAWASAKI, T; YAMAUCHI, T | 1 |
| Che, CM; Hui, Y; Shum, TY; Wong, EL; Yang, Z | 1 |
| Liu, XK; Ma, YH; Yang, SL | 1 |
| Che, CM; Cheung, YH; Chiu, JF; He, QY; Wang, Y; Yang, Z | 1 |
| Li, M; Yu, B | 1 |
| Kang, LP; Lü, N; Ma, BP; Tan, DW; Zhang, J | 1 |
| Asao, Y; Kumahara, A; Matsuda, H; Morikawa, T; Nakamura, S; Pongpiriyadacha, Y; Xu, F; Yoshikawa, M | 1 |
| Chen, J; Lin, S; Tong, Y; Wang, D; Yang, D; Yao, J | 1 |
| Li, M; Li, W; Qiu, Z; Wang, Y; Yu, B; Yu, J; Zhang, L; Zhang, Y; Zhu, Z | 1 |
| Che, CM; Chiu, JF; He, QY; Wang, Y | 1 |
| Kim, J; Yoon, KD | 1 |
| Lin, F; Wang, R | 1 |
| Han, J; Jiang, DX; Liu, XL; Liu, YT; Wang, GX; Zhao, LW | 1 |
| Ali, Z; Khan, IA; Smillie, TJ | 1 |
| Dong, D; Han, X; Lv, L; Peng, J; Qi, Y; Xu, L; Xu, Y; Yin, L; Zheng, L | 1 |
| Ji, S; Li, Y; Lv, L; Wang, B; Zhang, G; Zhang, H; Zhao, L; Zhou, G | 1 |
| Chen, HB; He, XC; Pang, YX; Tang, YN; Yi, T; Zhang, JY; Zhang, YZ; Zhao, ZZ | 1 |
| Hong, JH; Kim, YS; Lee, CJ; Lee, HJ; Lee, SK; Park, JS; Shin, YJ; Son, KH; Yoon, YP | 1 |
| Ali, Z; Aumsuwan, P; Avula, B; Dasmahapatra, AK; Helferich, WG; Katzenellenbogen, BS; Khan, IA; Khan, SI; Shariat-Madar, Z; Walker, LA | 1 |
| Goto, T; Hoshino, S; Kawada, T; Takahashi, N; Taketani, K; Tsuge, N; Uemura, T | 1 |
| Chen, P; Jin, HY; Ma, SC; Sun, L | 1 |
| Ji, L; Liang, T; Liang, Y; Liu, R; Shi, L; Xu, L; Yang, F; Yao, N | 1 |
| Cho, Y; Choi, SZ; Kang, KB; Ryu, J; Son, M; Sung, SH | 1 |
| Agnihotri, VK; Chand, G; Kumar, A; Maurya, AK | 1 |
| An, L; Ma, J; Piao, X; Wang, H; Wu, X; Yuan, Y; Zhang, J; Zhou, L | 1 |
| Liu, X; Ma, Z; Ren, S; Wang, L; Xu, F; Yang, L | 1 |
| Anand, U; Bandopadhyay, S; Behl, T; Dey, A; Gadekar, VS; Gupta, PK; Jha, NK; Kumar, M; Shekhawat, MS | 1 |
2 review(s) available for dioscin and beta-escin
| Article | Year |
|---|---|
Recent Advances in the Pharmacological Activities of Dioscin.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Antioxidants; Diosgenin; Humans; Saponins | 2019 |
Dioscin: A review on pharmacological properties and therapeutic values.
Topics: Diosgenin; Humans; Neoplasms; Plant Extracts; Saponins | 2022 |
34 other study(ies) available for dioscin and beta-escin
| Article | Year |
|---|---|
Antineoplastic agents; I. Three spirostanol glycosides from rhizomes of Dioscorea collettii var. hypoglauca.
Topics: Antineoplastic Agents; Carbohydrate Conformation; Carbohydrate Sequence; Diosgenin; Drugs, Chinese Herbal; Glycosides; Molecular Sequence Data; Saponins; Spirostans; Tumor Cells, Cultured | 1996 |
Synthesis of three diosgenyl saponins: dioscin, polyphyllin D, and balanitin 7.
Topics: Carbohydrate Conformation; Carbohydrate Sequence; Diosgenin; Glycosylation; Indicators and Reagents; Models, Molecular; Molecular Sequence Data; Optical Rotation; Saponins; Spectrometry, Mass, Fast Atom Bombardment | 1999 |
Effects of two saponins extracted from the polygonatum Zanlanscianense pamp on the human leukemia (HL-60) cells.
Topics: Apoptosis; Cell Differentiation; Cell Division; Diosgenin; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Magnetic Resonance Spectroscopy; Magnoliopsida; Molecular Structure; Saponins | 2001 |
A facile approach to diosgenin and furostan type saponins bearing a 3beta-chacotriose moiety.
Topics: Antineoplastic Agents; Diosgenin; Magnetic Resonance Spectroscopy; Saponins; Tropanes | 2002 |
Synthesis of monomethylated dioscin derivatives and their antitumor activities.
Topics: Animals; Antineoplastic Agents; Cell Division; Diosgenin; Humans; Methylation; Mice; Saponins; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
The synthesis of gracillin and dioscin: two typical representatives of spirostanol glycosides.
Topics: Acetylation; Carbohydrate Conformation; Diosgenin; Guanidine; Saponins; Spirostans | 2003 |
A new steroidal saponin from Dioscorea zingiberensis Wright.
Topics: Dioscorea; Diosgenin; Magnetic Resonance Spectroscopy; Molecular Structure; Rhizome; Saponins; Sterols | 2003 |
[Apoptosis of human chronic myeloid leukemia k562 cell induced by prosapogenin B of dioscin (P.B) in vitro].
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Diosgenin; Flow Cytometry; Humans; K562 Cells; Microscopy, Electron, Scanning; Saponins | 2003 |
Saponins of Japanese Dioscoreaceae. V. On the structure of dioscin.
Topics: Dioscoreaceae; Diosgenin; Saponins | 1956 |
Structures of dioscin, gracillin, and kikuba-saponin. 2. (Saponins of Japanese Dioscoreaceae. XI.
Topics: Dioscoreaceae; Diosgenin; Plants; Saponins; Spirostans; Steroids | 1962 |
Fluorophore-appended steroidal saponin (dioscin and polyphyllin D) derivatives.
Topics: Carbohydrate Conformation; Cell Survival; Diosgenin; Fluorides; Glycosylation; HeLa Cells; Humans; Models, Molecular; Saponins; Steroids; Trisaccharides | 2005 |
[Steroidal constituents from Dioscorea parviflora].
Topics: Dioscorea; Diosgenin; Molecular Conformation; Molecular Structure; Plants, Medicinal; Rhizome; Saponins; Steroids | 2005 |
Proteomic approach to study the cytotoxicity of dioscin (saponin).
Topics: Apoptosis; Diosgenin; Drug Screening Assays, Antitumor; Electrophoresis, Gel, Two-Dimensional; HL-60 Cells; Humans; Membrane Potentials; Mitochondria; Models, Chemical; Polygonatum; Proteomics; Saponins; Silver Staining; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2006 |
Facile conversion of spirostan saponin into furostan saponin: synthesis of methyl protodioscin and its 26-thio-analogue.
Topics: Cholestanes; Diosgenin; Hydrocarbons, Iodinated; Molecular Structure; Saponins; Spirostans; Sulfur Compounds | 2006 |
[Study on steroidal saponins of Dioscorea septemloba thunb].
Topics: Dioscorea; Diosgenin; Molecular Structure; Plant Tubers; Plants, Medicinal; Saponins; Steroids | 2006 |
Medicinal flowers. XII.(1)) New spirostane-type steroid saponins with antidiabetogenic activity from Borassus flabellifer.
Topics: Animals; Arecaceae; Blood Glucose; Diosgenin; Dose-Response Relationship, Drug; Hypoglycemic Agents; Male; Methanol; Molecular Structure; Plant Extracts; Plants, Medicinal; Rats; Rats, Wistar; Saponins; Time Factors | 2007 |
Characterization of steroidal saponins in crude extract from Dioscorea nipponica Makino by liquid chromatography tandem multi-stage mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Dioscorea; Diosgenin; Methanol; Plant Extracts; Rhizome; Saponins; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Synthesis, cytotoxicity, and hemolytic activity of 6'-O-substituted dioscin derivatives.
Topics: Cell Death; Cell Line, Tumor; Diosgenin; Erythrocytes; Hemolysis; Humans; Saponins | 2007 |
Dioscin (saponin)-induced generation of reactive oxygen species through mitochondria dysfunction: a proteomic-based study.
Topics: Amino Acid Sequence; Antineoplastic Agents; Apoptosis; Diosgenin; HL-60 Cells; Humans; Microsomes; Mitochondria; Molecular Sequence Data; Proteomics; Reactive Oxygen Species; Saponins | 2007 |
Preparative separation of dioscin derivatives from Dioscorea villosa by centrifugal partition chromatography coupled with evaporative light scattering detection.
Topics: Carbohydrate Sequence; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dioscorea; Diosgenin; Light; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Plant Roots; Saponins; Scattering, Radiation; Solvents; Spectrometry, Mass, Electrospray Ionization; Spirostans | 2008 |
Hemolytic mechanism of dioscin proposed by molecular dynamics simulations.
Topics: Alkanes; Cholesterol; Diosgenin; Hemolysis; Lipid Bilayers; Membrane Microdomains; Molecular Dynamics Simulation; Molecular Structure; Saponins; Water | 2010 |
Anthelmintic activity of steroidal saponins from Paris polyphylla.
Topics: Animals; Anthelmintics; Diosgenin; Goldfish; Liliaceae; Plant Extracts; Rhizome; Saponins; Trematoda | 2010 |
Two spirostan steroid glycoside fatty esters from Dioscorea cayenensis.
Topics: Dioscorea; Diosgenin; Glycosides; Magnetic Resonance Spectroscopy; Molecular Structure; Saponins; Spirostans | 2013 |
Dioscin, a natural steroid saponin, induces apoptosis and DNA damage through reactive oxygen species: a potential new drug for treatment of glioblastoma multiforme.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Diosgenin; DNA Damage; Glioblastoma; Male; Membrane Potential, Mitochondrial; Mitochondria; Neoplasm Proteins; Neoplasm Transplantation; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Saponins; Survival Analysis; Tumor Burden | 2013 |
Liquid chromatography tandem mass spectrometry in study of the pharmacokinetics of six steroidal saponins in rats.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Diosgenin; Drug Stability; Ginsenosides; Magnoliopsida; Male; Rats; Rats, Sprague-Dawley; Saponins; Sensitivity and Specificity; Spirostans; Tandem Mass Spectrometry | 2013 |
UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins: a comparative study.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Dioscorea; Diosgenin; Drugs, Chinese Herbal; Feces; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley; Saponins | 2015 |
Dioscin and methylprotodioscin isolated from the root of Asparagus cochinchinensis suppressed the gene expression and production of airway MUC5AC mucin induced by phorbol ester and growth factor.
Topics: Asparagus Plant; Cell Line, Tumor; Diosgenin; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Humans; Mucin 5AC; Plant Roots; Saponins; Tetradecanoylphorbol Acetate | 2015 |
The anticancer potential of steroidal saponin, dioscin, isolated from wild yam (Dioscorea villosa) root extract in invasive human breast cancer cell line MDA-MB-231 in vitro.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Dioscorea; Diosgenin; Dose-Response Relationship, Drug; Humans; MCF-7 Cells; Neoplasm Invasiveness; Phytosterols; Plant Extracts; Plant Roots; Saponins; Treatment Outcome | 2016 |
An Efficient Purification Method for Quantitative Determinations of Protodioscin, Dioscin and Diosgenin in Plasma of Fenugreek-Fed Mice.
Topics: Animals; Chloroform; Chromatography, High Pressure Liquid; Diosgenin; Male; Methanol; Mice, Obese; Plant Extracts; Saponins; Solid Phase Extraction; Tandem Mass Spectrometry; Trigonella | 2015 |
Multi-component determination and chemometric analysis of Paris polyphylla by ultra high performance liquid chromatography with photodiode array detection.
Topics: Chromatography, High Pressure Liquid; Diosgenin; Drugs, Chinese Herbal; Liliaceae; Quality Control; Saponins | 2016 |
Exploration in the cascade working mechanisms of liver injury induced by total saponins extracted from Rhizoma Dioscorea bulbifera.
Topics: Animals; Apoptosis; Bile Acids and Salts; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytochrome P-450 Enzyme System; Dioscorea; Diosgenin; Female; Homeostasis; Humans; Liver; Male; Mitochondria; Oxidative Stress; Rats, Wistar; Rhizome; Saponins; Signal Transduction; Up-Regulation | 2016 |
Combined Application of UHPLC-QTOF/MS, HPLC-ELSD and
Topics: Chromatography, High Pressure Liquid; Dioscorea; Diosgenin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Preparations; Quality Control; Reproducibility of Results; Saponins; Spectrometry, Mass, Electrospray Ionization | 2017 |
Comparative metabolic profiling of Costus speciosus leaves and rhizomes using NMR, GC-MS and UPLC/ESI-MS/MS.
Topics: Caffeic Acids; Costus; Diosgenin; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Metabolomics; Plant Extracts; Plant Leaves; Plants, Medicinal; Rhizome; Saponins; Sesquiterpenes; Spectrometry, Mass, Electrospray Ionization; Steroids; Sterols; Tandem Mass Spectrometry | 2018 |
NMR-based metabolomics approach to investigate the distribution characteristics of metabolites in Dioscorea opposita Thunb. cv. Tiegun.
Topics: Cluster Analysis; Dioscorea; Diosgenin; Leucine; Magnetic Resonance Spectroscopy; Metabolomics; Plant Exudates; Plants, Medicinal; Principal Component Analysis; Saponins | 2019 |