dinoprost has been researched along with titanium-dioxide* in 1 studies
1 other study(ies) available for dinoprost and titanium-dioxide
Article | Year |
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Mass or total surface area with aerosol size distribution as exposure metrics for inflammatory, cytotoxic and oxidative lung responses in rats exposed to titanium dioxide nanoparticles.
There is currently no consensus on the best exposure metric(s) for expressing nanoparticle (NP) dose. Although surface area has been extensively studied for inflammatory responses, it has not been as thoroughly validated for cytotoxicity or oxidative stress effects. Since inhaled NPs deposit and interact with lung cells based on agglomerate size, we hypothesize that mass concentration combined with aerosol size distribution is suitable for NP risk assessment. The objective of this study was to evaluate different exposure metrics for inhaled 5 nm titanium dioxide aerosols composed of small (SA < 100 nm) or large (LA > 100 nm) agglomerates at 2, 7, and 20 mg/m Topics: Aerosols; Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Cell Death; Dinoprost; Dose-Response Relationship, Drug; Inhalation Exposure; Lung; Male; Metal Nanoparticles; Neutrophil Infiltration; Oxidants; Oxidative Stress; Particle Size; Rats, Inbred F344; Respiratory Mucosa; Surface Properties; Titanium; Toxicity Tests, Acute | 2017 |