dinoprost has been researched along with harpagoside* in 1 studies
1 other study(ies) available for dinoprost and harpagoside
| Article | Year |
|---|---|
Optimization of Aqueous Extraction and Biological Activity of Harpagophytum procumbens Root on Ex Vivo Rat Colon Inflammatory Model.
Harpagophytum procumbens has a long story of use for the treatment of inflammatory diseases. Considering both the antiinflammatory effects of H. procumbens in multiple tissues and the stability of harpagoside in artificial intestinal fluid, the aim of the present study was to explore the possible protective role of a microwave-assisted aqueous Harpagophytum extract (1-1000 μg/mL) on mouse myoblast C2C12 and human colorectal adenocarcinoma HCT116 cell lines, and isolated rat colon specimens challenged with lipopolysaccharide (LPS), a validated ex vivo model of acute ulcerative colitis. In this context, we evaluated the effects on C2C12 and HCT116 viability, and on LPS-induced production of serotonin (5-HT), tumor necrosis factor (TNF)-α, prostaglandin (PG)E Topics: Animals; Cell Line, Tumor; Colon; Dinoprost; Dinoprostone; Glycosides; Harpagophytum; Humans; Inflammatory Bowel Diseases; Lipopolysaccharides; Male; Mice; Oxidative Stress; Plant Extracts; Plant Roots; Pyrans; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha | 2017 |