dinoprost has been researched along with fluacrypyrim* in 1 studies
1 other study(ies) available for dinoprost and fluacrypyrim
| Article | Year |
|---|---|
Flucrypyrim, a novel uterine relaxant, has antinociceptive and anti-inflammatory effects in vivo.
Consequences of primary dsysmenorrhea (PD) can be severe. Increased prostaglandin production leads to uterine contraction and insufficient blood flow to the endometrium causing ischemia and pain symptoms. Protein tyrosine kinase/phosphatase activities contribute to the modulation of uterine contraction. In our previous study, we found the synthetic β-methoxyacrylates compound Fluacrypyrim (FAPM), significantly increased protein tyrosine phosphatases (PTPs) activity, resulting in dephosphorylation of tyrosine kinases. In the present study, we found that FAPM near completely inhibited prostaglandin F2α (PGF Topics: Acrylates; Analgesics; Animals; Anti-Inflammatory Agents; Dinoprost; Mice; Nociceptive Pain; Pyrimidines; Rats; Structure-Activity Relationship; Uterine Contraction | 2017 |