Compounds > dinophysistoxin 1
Page last updated: 2024-08-26

dinophysistoxin 1 and okadaic acid

dinophysistoxin 1 has been researched along with okadaic acid in 136 studies

Research

Studies (136)

TimeframeStudies, this research(%)All Research%
pre-19903 (2.21)18.7374
1990's40 (29.41)18.2507
2000's24 (17.65)29.6817
2010's55 (40.44)24.3611
2020's14 (10.29)2.80

Authors

AuthorsStudies
Rinehart, KL; Sakai, R1
Cho, Y; Konoki, K; Matsuura, H; Saito, K; Sugiyama, N; Tachibana, K; Yotsu-Yamashita, M1
Brautigan, DL; Eriksson, JE; Fujiki, H; Goldman, RD; Olmsted, J; Vallee, R1
Chubb, CH; Fujiki, H; Giometti, C; Huberman, E; Kiguchi, K1
Hu, T; Marr, JC; Pleasance, S; Quilliam, MA; Wright, JL1
Marr, JC; Pleasance, S; Quilliam, MA1
Aune, T; Stabell, OB; Steffenak, I1
Isono, K; Kurisaki, T; Magae, J; Nagai, K; Yamasaki, M1
Eriksson, JE; Fujiki, H; Goldman, RD; Olson, MO; Suganuma, M; Yatsunami, J; Yoshizawa, S1
Fujiki, H; Nishiwaki, S; Suganuma, M; Sugimura, T; Winyar, B; Yoshizawa, S1
Fujiki, H; Levine, L; Nishiwaki, S; Ojika, M; Suganuma, M; Yamada, K; Yatsunami, J1
Pedersen, K; Stabell, OB; Steffenak, I; Underdal, B1
Aune, T; Engeland, E; Yasumoto, T1
Fujiki, H; Sakai, A1
Hormazabal, V; Pedersen, K; Stabell, OB; Steffenak, I1
Fujiki, H; Nishiwaki, S; Schmitz, FJ; Suganuma, M; Sugimura, T; Winyar, B; Yoshizawa, S1
Carrier, F; Holmes, CF; Luu, HA; Schmitz, FJ1
Fujiki, H; Hirasawa, N; Ohashi, M; Ohuchi, K; Tamura, T; Tsurufuji, S; Watanabe, M1
Fujiki, H; Murata, M; Suganuma, M; Suguri, H; Takagi, K; Uda, N; Wakamatsu, K; Yamada, K; Yasumoto, T; Yoshizawa, S1
Ito, E; Terao, K; Yanagi, T; Yasumoto, T1
Ito, E; Terao, K1
Kita, H; Matsuura, S; Takagaki, Y1
Adamson, A; Conlon-Kelly, A; Marr, JC; McLachlan, JL1
Marr, JC; McDowell, LM; Quilliam, MA1
Iwata, H; Nakanishi, H; Suganuma, M; Tatematsu, M; Yoshida, K; Yuasa, H1
Chen, DZ; Holmes, CF; Luu, HA; Magoon, J; Smith, J; Worms, J1
Lawrence, JF; Ménard, C; Roussel, S1
Gago-Martinez, A; Quilliam, MA; Rodriguez-Vazquez, JA; Thibault, P1
Boria, P; Draisci, R; Giannetti, L; Lucentini, L; Stacchini, A1
De Lanerolle, P; Hecht, G; Koutsouris, A; Pestic, L; Tripuraneni, J1
Akasaka, K; Meguro, H; Ohrui, H; Yasumoto, T1
Hummert, C; Luckas, B; Shen, JL1
Aase, B; Rogstad, A1
Núñez, PE; Scoging, AC1
Botana, LM; González, JC; Vieites, JM; Vieytes, MR1
Hopkins, WF1
Aune, T; Nordstoga, K; Stabell, OB; Tjøtta, K1
Aune, T; Døskeland, SO; Fladmark, KE; Larsen, NL; Serres, MH; Yasumoto, T1
Ota, H; Suzuki, T; Yamasaki, M1
Oteri, G; Stammati, A; Zampaglioni, F; Zucco, F1
Guilbault, GG; Kreuzer, MP; O'Sullivan, CK1
Comesaña Losada, M; Gago-Martínez, A; Leão, JM; Quilliam, MA; Rodríguez Vázquez, JA1
Suzuki, T; Yasumoto, T1
Botana, AM; Botana, LM; González, JC; Leira, F; Vieites, JM; Vieytes, MR1
Holmes, MJ; Khoo, HW; Teo, SL1
Della Loggia, R; Sosa, S; Tubaro, A1
Mitsuya, T; Suzuki, T1
Bravo, I; Fernández, ML; Martínez, A; Ramilo, I1
Chen, Z; He, X; Li, D; Lin, B; Sun, L1
Arredondo-Vega, BO; Heredia-Tapia, A; Nuñez-Vázquez, EJ; Ochoa, JL; Yasuda, M; Yasumoto, T1
Andersen, RJ; Britton, R; Brown, C; Roberge, M; van Soest, R1
Lu, Y; Monsivais, P; Rubel, EW; Tempel, BL1
García, C; Lagos, N; Liberona, JL; Rivas, M1
Morris, S; Nascimento, SM; Purdie, DA1
Delauney-Bertoncini, N; Hennion, MC; Lau, BP; Lawrence, JF; Lewis, D; Ménard, C; Niedzwiadek, B; Rawn, DF1
Díaz, JC; García, C; Lagos, M; Lagos, N; Santelices, JP; Truan, D1
Beuzenberg, V; Cooney, JM; Hawkes, AD; Jensen, DJ; Larsen, K; Lincoln Mackenzie, A; Miles, CO; Petersen, D; Rise, F; Wilkins, AL1
Kaniou-Grigoriadou, I; Kouimtzis, T; Mouratidou, T; Samara, C1
Arcus, V; Goldstone, D; Hess, P; Hovgaard, P; Larsen, K; Miles, CO; Petersen, D; Rehmann, N; Rise, F; Rundberget, T; Samdal, IA; Sandvik, M; Wilkins, AL1
Miles, CO; Rundberget, T; Torgersen, T; Wilkins, AL1
Undeland, I; Vareltzis, P1
Cañete, E; Diogène, J1
Georgantelis, D; Katikou, P; Kyritsakis, A; Prassopoulou, E1
He, Y; Liu, JS; Yang, WD; Zhang, JL; Zhong, N1
Amorim, A; Vale, P; Veloso, V1
Connolly, L; Curran, RM; Elliott, CT; Stewart, LD; Walker, AD1
Badeka, AV; Katikou, P; Kontominas, MG; Louppis, AP; Paleologos, EK1
Arcus, V; Cox, NR; Huhn, J; Jeffrey, PD; Larsen, K; Miles, CO; Rise, F; Rundberget, T; Shi, Y1
Daranas, AH; Dominguez, HJ; Fernández, JJ; Franco, JM; Norte, M; Paz, B1
Connolly, L; Elliott, CT; Hess, P; Stewart, LD1
Alfonso, A; Alfonso, C; Botana, LM; Otero, P; Rodríguez, P; Vieytes, MR1
Bovee, TF; Elliott, CT; Hendriksen, PJ; Hoogenboom, LA; Nielen, MW; Peijnenburg, AA; Portier, L; van Egmond, HP; Wang, S1
Armi, Z; Ceredi, A; Milandri, A; Riccardi, E; Trabelsi, E; Turki, S1
Cao, J; Li, A; Ma, J; McCarron, P1
Guo, M; Li, Z; Tan, Z; Wu, H; Zhai, Y1
Fraser, SE; Huss, D; Kashima, DT; Lansford, R; Poynter, G; Rubel, EW; Sanchez, JT; Schecterson, L; Seidl, AH; Tabor, KM; Wang, Y1
Li, YS; Li, ZH; Lin, C; Liu, ZS; Lu, SY; Meng, XM; Ren, HL; Yan, DM; Yu, SY; Zhou, Y1
Chen, G; Hou, L; Li, J; Liu, B; Tang, D; Zhang, B1
Jung, JH; Kim, JH; Lee, DS; Lee, KJ; Mok, JS; Song, KC; Yu, H1
Cai, X; Zhang, X1
Campàs, M; de la Iglesia, P; Diogène, J; Garibo, D1
Borchert, J; Duchin, JS; Lloyd, JK; Quintana, HF; Robertson, A1
Franco, JM; Reguera, B; Riobó, P; Rodríguez, F1
Baibado, JT; Cheung, HY; Dai, Z; Dong, W; Gong, L; Shen, Q; Wang, Y1
Botana, LM; Fernández, DA; Fraga, M; Louzao, MC; Vieytes, MR; Vilariño, N1
Gong, S; Guo, YP; Hu, P; Li, L; Li, YS; Lin, C; Liu, ZS; Lu, SY; Ren, HL; Tan, CY; Zhou, Y1
Ferron, PJ; Fessard, V; Hogeveen, K; Le Hégarat, L1
Diogène, J; Soliño, L; Sureda, FX1
Fan, L; Hess, P; Li, A; Ma, Q; Qiu, J; Sun, G1
Botana, LM; Cantalapiedra, AG; Carrera, C; Ferreiro, SF; Louzao, MC; Santamarina, G; Vilariño, N1
Abal, P; Botana, LM; Fernández, DA; Fraga, M; Louzao, MC; Vieytes, MR; Vilariño, N1
Kane, M; Kilcoyne, M; Le Berre, M1
Broadwater, MH; Ramsdell, JS; Wang, Z1
Efimova, KV; Kameneva, PA; Orlova, TY; Rybin, VG1
Kamio, M; Kaneniwa, M; Matsushima, R; Nagai, H; Nagai, S; Suzuki, T; Uchida, H; Watanabe, R1
Kajimura, K; Kakimoto, K; Nagayoshi, H; Okihashi, M; Yamaguchi, M; Yamaguchi, T1
Fujita, K; Igarashi, T; Inagaki, M; Kato, T; Nagae, M; Saito, M; Watai, M; Yasumoto, T1
Beach, DG; Burton, IW; Crain, S; Giddings, SD; Hardstaff, WR; Kilcoyne, J; LeBlanc, P; Lewis, N; Martinez-Farina, CF; McCarron, P; Melanson, JE; Perez, RA; Quilliam, MA; Stefanova, R1
Beach, DG; Giddings, SD; McCarron, P; Quilliam, MA; Reeves, KL1
Emteborg, H; McCarron, P; Quilliam, MA; Wright, E1
Del Campo, M; García, L; Lagos, N; Tampe, R; Zhong, TY1
Burton, IW; Hu, T; LeBlanc, P; McCarron, P; Melanson, JE; Strangman, WK; Walter, JA; Wright, JLC1
Jeong, EJ; Kim, HS; Lee, S; Rho, JR; Yang, AR; Yoo, YD1
Jiang, T; Li, Y; Liu, L; Lu, S; Tan, Z; Wu, H; Zhang, J1
Chen, ZF; Dai, L; Kong, FZ; Li, C; Liu, Y; Yu, RC; Zhou, MJ1
Le Du, J; Núñez-Vázquez, EJ; Tovar-Ramírez, D1
Bodero, M; Bovee, TFH; de Haan, L; Hendriksen, PJM; Hoogenboom, RLAP; Peijnenburg, A; Portier, L1
Kameneva, PA; Krasheninina, EA; Kukla, SP; Orlova, TY; Slobodskova, VV1
Inagaki, S; Kawaguchi, M; Suzuki, T; Takatsu, A; Uchida, H; Yamazaki, T; Yarita, T1
Okada, Y; Suzuki, H1
Chis, V; Glamuzina, B; Müller, C; Pinzaru, SC; Ujević, I; Venter, MM1
Che, Y; Hu, Y; Ji, Y; Li, A; Li, M; Qiu, J; Song, J; Wang, S1
Abal, P; Botana, AM; Botana, LM; Carrera, C; Louzao, MC; Suzuki, T; Vieytes, MR; Vilariño, N; Watanabe, R1
Akamine, T; Kanamori, M; Kosaka, Y; Matsushima, R; Oikawa, H; Oogida, I; Suzuki, T; Uchida, H; Watanabe, R1
Bresnan, E; Davidson, K; McNeill, S; Mitchell, E; Paterson, RF; Swan, SC; Turner, AD; Whyte, C1
Mackenzie, LA1
Espiña, B; Fernandes, SPS; Kolen'ko, YV; Rodriguez-Lorenzo, L; Romero, V; Salonen, LM1
Chen, ZF; Dai, L; Geng, HX; Kong, FZ; Li, C; Liu, Y; Yu, RC; Zhou, MJ1
Inagaki, S; Kawaguchi, M; Miyamoto, A; Suzuki, T; Takatsu, A; Uchida, H; Yamazaki, T; Yarita, T1
Harwood, DT; Hoppenrath, M; Kazandjian, A; Murray, JS; Murray, SA; Pargmann, I; Sarowar, C; Verma, A1
Chen, J; Chen, K; He, X; Liu, L; Ma, X; Sun, P; Wang, B; Wang, J; Wu, D1
Arévalo, F; Blanco, J; Correa, J; Moroño, Á1
Chen, L; Du, S; Lin, Z; Liu, Y; Yu, R; Zhang, L; Zhang, P; Zhou, Y1
Contreras, HR; García, C; Jiménez-Cárcamo, D1
Fessard, V; Le Hegarat, L; Roudot, AC1
Chen, J; He, X; Pan, L; Shen, H; Zhan, T1
Ai, Q; Fang, Y; Ji, Y; Li, A; Qiu, J; Wang, S; Zhao, M1
Boundy, MJ; Finch, S; Harwood, DT; Kiermeier, A; McLeod, C; Nicolas, J1
Drapeau, O; Fessard, V; Huguet, A; Quenault, H; Rousselet, F1
Burrell, S; Kilcoyne, J; Miles, CO; Nulty, C; Rajotte, I; Salas, R; Wright, EJ1
Abal, P; Botana, AM; Botana, LM; Costas, C; Louzao, MC; R Vieytes, M; Suzuki, T; Vilariño, N; Watanabe, R1
Doucette, GJ; Wang, Z1
Li, J; Mao, X; Sun, J; Wang, L; Wang, S; Wang, W; Zhang, L1
Álvarez, G; Araya, M; Arenas-Uribe, S; Baldrich, ÁM; Barrera, F; Díaz, M; Díaz, PA; Fernández-Pena, C; Navarro, P; Nieves, MG; Pérez-Santos, I; Reguera, B; Rodríguez-Villegas, C; Schwerter, C1
Basti, L; Kuribayashi, T; Lum, WM; Matsushima, R; Nagai, S; Nakayama, N; Natsuike, M; Sildever, S; Uchida, H1
Chun, HS; Hwang, JH; Jung, HJ; Kang, JH; Oh, SH; Park, SY; Yoon, YS1

Reviews

1 review(s) available for dinophysistoxin 1 and okadaic acid

ArticleYear
Dinoflagellate polyether within the yessotoxin, pectenotoxin and okadaic acid toxin groups: characterization, analysis and human health implications.
    Toxicon : official journal of the International Society on Toxinology, 2010, Aug-15, Volume: 56, Issue:2

    Topics: Animals; Dinoflagellida; Humans; Liver; Macrolides; Mice; Molecular Structure; Mollusk Venoms; Myocardium; Necrosis; Okadaic Acid; Oxocins; Pyrans; Rats; Shellfish; Shellfish Poisoning; Toxicity Tests

2010

Other Studies

135 other study(ies) available for dinophysistoxin 1 and okadaic acid

ArticleYear
A new polyether acid from a cold water marine sponge, a Phakellia species.
    Journal of natural products, 1995, Volume: 58, Issue:5

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cricetinae; Haplorhini; Herpesvirus 1, Human; Magnetic Resonance Spectroscopy; Porifera; Pyrans; Spectrometry, Mass, Fast Atom Bombardment; Tumor Cells, Cultured; Vesicular stomatitis Indiana virus

1995
Binding of diarrheic shellfish poisoning toxins to okadaic acid binding proteins purified from the sponge Halichondria okadai.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Animals; Carrier Proteins; Cell Line, Tumor; Marine Toxins; Mice; Okadaic Acid; Porifera; Protein Binding; Pyrans; Recombinant Proteins

2010
Cytoskeletal integrity in interphase cells requires protein phosphatase activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22

    Topics: Animals; Cell Line; Cricetinae; Cytoskeleton; Ethers, Cyclic; Interphase; Kinetics; Marine Toxins; Okadaic Acid; Oxazoles; Peptide Mapping; Phosphopeptides; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Kinases; Pyrans; Vimentin

1992
Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A.
    Biochemical and biophysical research communications, 1992, Dec-30, Volume: 189, Issue:3

    Topics: Antibodies, Monoclonal; Autoradiography; Blotting, Northern; Breast Neoplasms; Caseins; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Ethers, Cyclic; Female; Fluorescent Antibody Technique; Gene Expression; Genes, fos; Genes, jun; Humans; Isoenzymes; Kinetics; Marine Toxins; Microcystins; Okadaic Acid; Oligonucleotide Probes; Oxazoles; Peptides, Cyclic; Phosphates; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Pyrans; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1992
Detection of new 7-O-acyl derivatives of diarrhetic shellfish poisoning toxins by liquid chromatography-mass spectrometry.
    Toxicon : official journal of the International Society on Toxinology, 1992, Volume: 30, Issue:12

    Topics: Acylation; Animals; Bivalvia; Chromatography, Liquid; Chromatography, Thin Layer; Diarrhea; Ethers, Cyclic; Hydrolysis; Magnetic Resonance Spectroscopy; Marine Toxins; Mass Spectrometry; Okadaic Acid; Pyrans; Shellfish; Spectrophotometry, Ultraviolet; Vasoconstrictor Agents

1992
Ionspray mass spectrometry of marine toxins. IV. Determination of diarrhetic shellfish poisoning toxins in mussel tissue by liquid chromatography/mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 1992, Volume: 6, Issue:2

    Topics: Animals; Bivalvia; Ethers, Cyclic; Gas Chromatography-Mass Spectrometry; Marine Toxins; Okadaic Acid; Pyrans

1992
An evaluation of the mouse bioassay applied to extracts of 'diarrhoetic' shellfish toxins.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1992, Volume: 30, Issue:2

    Topics: Animals; Biological Assay; Bivalvia; Body Weight; Diarrhea; Dose-Response Relationship, Drug; Ethers, Cyclic; Marine Toxins; Mice; Okadaic Acid; Pyrans

1992
Effects of tautomycin, a protein phosphatase inhibitor, on recycling of mammalian cell surface molecules.
    The Journal of antibiotics, 1992, Volume: 45, Issue:2

    Topics: Alkaloids; Antifungal Agents; Carbazoles; CD4 Antigens; Down-Regulation; Ethers, Cyclic; Indole Alkaloids; Okadaic Acid; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrans; Receptors, Transferrin; Spiro Compounds; Staurosporine

1992
Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid.
    Biochemical and biophysical research communications, 1991, Jun-28, Volume: 177, Issue:3

    Topics: Blotting, Western; Ethers, Cyclic; Fibroblasts; Humans; Kinetics; Marine Toxins; Molecular Weight; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 1; Protein Phosphatase 2; Pyrans; Vimentin

1991
Mechanisms of action of okadaic acid class tumor promoters on mouse skin.
    Environmental health perspectives, 1991, Volume: 93

    Topics: Animals; Carcinogens; DNA; DNA Damage; DNA, Neoplasm; Enzyme Activation; Ethers, Cyclic; Genes, ras; Humans; Marine Toxins; Mice; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinases; Protein Processing, Post-Translational; Proteins; Pyrans; Receptors, Drug; Skin; Skin Neoplasms; Structure-Activity Relationship

1991
Binding competition of okadaic acid derivatives to anti-okadaic acid antibody.
    Toxicon : official journal of the International Society on Toxinology, 1991, Volume: 29, Issue:11

    Topics: Animals; Antibody Specificity; Antigen-Antibody Reactions; Binding, Competitive; Ethers, Cyclic; Okadaic Acid; Pyrans; Rabbits; Radioimmunoassay; Spiro Compounds

1991
Diversity of shellfish toxins of "diarrhetic" type revealed by biological and chemical assays.
    Journal of toxicology and environmental health, 1991, Volume: 33, Issue:3

    Topics: Animals; Bivalvia; Carcinogens; Chromatography, High Pressure Liquid; Diarrhea; Ethers, Cyclic; Marine Toxins; Mice; Okadaic Acid; Pyrans

1991
Light and scanning electron microscopic studies on effects of marine algal toxins toward freshly prepared hepatocytes.
    Journal of toxicology and environmental health, 1991, Volume: 34, Issue:1

    Topics: Animals; Bacterial Toxins; Bivalvia; Cells, Cultured; Cyanobacteria Toxins; Diarrhea; Dose-Response Relationship, Drug; Ethers, Cyclic; L-Lactate Dehydrogenase; Liver; Macrolides; Male; Marine Toxins; Microcystins; Microscopy, Electron, Scanning; Mollusk Venoms; Okadaic Acid; Oxocins; Pyrans; Rats; Shellfish

1991
Promotion of BALB/3T3 cell transformation by the okadaic acid class of tumor promoters, okadaic acid and dinophysistoxin-1.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:5

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Dinoflagellida; Ethers, Cyclic; Marine Toxins; Mice; Mice, Inbred Strains; Okadaic Acid; Pyrans

1991
Diarrhetic shellfish toxins: improvement of sample clean-up for HPLC determination.
    Toxicon : official journal of the International Society on Toxinology, 1991, Volume: 29, Issue:1

    Topics: Animals; Anthracenes; Bivalvia; Chromatography, High Pressure Liquid; Esters; Ethers, Cyclic; Fluorescent Dyes; Marine Toxins; Okadaic Acid; Pyrans; Reproducibility of Results; Ultrasonics

1991
A new pathway of tumor promotion by the okadaic acid class compounds.
    Advances in second messenger and phosphoprotein research, 1990, Volume: 24

    Topics: Animals; Binding, Competitive; Brain; Carcinogens; Cytosol; DNA, Neoplasm; Ethers, Cyclic; Humans; Marine Toxins; Mice; Molecular Structure; Mutation; Nuclear Proteins; Nucleolin; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Protein Kinases; Proteins; Proto-Oncogene Proteins p21(ras); Pyrans; Receptors, Drug; RNA-Binding Proteins; Skin; Skin Neoplasms; Spiro Compounds; Structure-Activity Relationship

1990
Inhibition of protein phosphatases-1 and -2A with acanthifolicin. Comparison with diarrhetic shellfish toxins and identification of a region on okadaic acid important for phosphatase inhibition.
    FEBS letters, 1990, Sep-17, Volume: 270, Issue:1-2

    Topics: Ethers, Cyclic; Marine Toxins; Molecular Structure; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Pyrans; Spiro Compounds; Structure-Activity Relationship

1990
Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages.
    Biochimica et biophysica acta, 1989, Sep-04, Volume: 1013, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cells, Cultured; Dinoprostone; Ethers, Cyclic; Ionophores; Kinetics; Macrophages; Marine Toxins; Okadaic Acid; Pyrans; Rats; Tetradecanoylphorbol Acetate

1989
Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:10

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Enzyme Induction; Ethers, Cyclic; Female; Irritants; Marine Toxins; Mice; Okadaic Acid; Ornithine Decarboxylase; Pyrans; Skin Neoplasms; Structure-Activity Relationship

1988
Histopathological studies on experimental marine toxin poisoning. I. Ultrastructural changes in the small intestine and liver of suckling mice induced by dinophysistoxin-1 and pectenotoxin-1.
    Toxicon : official journal of the International Society on Toxinology, 1986, Volume: 24, Issue:11-12

    Topics: Animals; Animals, Suckling; Duodenum; Female; Liver; Macrolides; Male; Marine Toxins; Mice; Mice, Inbred BALB C; Microscopy, Electron; Okadaic Acid; Pyrans

1986
Injury and recovery process of intestine caused by okadaic acid and related compounds.
    Natural toxins, 1994, Volume: 2, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Cell Differentiation; Dinoflagellida; Epithelium; Ethers, Cyclic; Injections, Intraperitoneal; Intestines; Jejunum; Male; Marine Toxins; Mice; Mice, Inbred ICR; Microscopy, Electron; Microscopy, Electron, Scanning; Mycotoxins; Okadaic Acid; Pyrans; Trichothecenes

1994
Specificity of mouse monoclonal anti-okadaic acid antibodies to okadaic acid and its analogs among diarrhetic shellfish toxins.
    Bioscience, biotechnology, and biochemistry, 1994, Volume: 58, Issue:8

    Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Dinoflagellida; Enzyme-Linked Immunosorbent Assay; Ethers, Cyclic; Marine Toxins; Mice; Okadaic Acid; Pyrans

1994
Effects of nitrogen concentration and cold temperature on DSP-toxin concentrations in the dinoflagellate Prorocentrum lima (Prorocentrales, Dinophyceae).
    Natural toxins, 1994, Volume: 2, Issue:5

    Topics: Animals; Cell Count; Chromatography, High Pressure Liquid; Cold Temperature; Culture Media; Dinoflagellida; Ethers, Cyclic; Marine Toxins; Nitrogen; Okadaic Acid; Phosphoprotein Phosphatases; Pyrans; Reference Standards; Shellfish; Spectrometry, Fluorescence

1994
Investigation of derivatization reagents for the analysis of diarrhetic shellfish poisoning toxins by liquid chromatography with fluorescence detection.
    Natural toxins, 1994, Volume: 2, Issue:5

    Topics: Animals; Anthracenes; Chromatography, High Pressure Liquid; Coumarins; Dinoflagellida; Ethers, Cyclic; Fluorescent Dyes; Marine Toxins; Okadaic Acid; Pyrans; Pyrenes; Shellfish; Spectrometry, Fluorescence; Temperature; Umbelliferones

1994
Increase of labeling indices in gastrointestinal mucosae of mice and rats by compounds of the okadaic acid type.
    Journal of cancer research and clinical oncology, 1994, Volume: 120, Issue:4

    Topics: Administration, Oral; Animals; Antifungal Agents; Bromodeoxyuridine; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Ethers, Cyclic; Intestinal Mucosa; Male; Marine Toxins; Mice; Mice, Inbred ICR; Okadaic Acid; Oxazoles; Pyrans; Rats; Rats, Sprague-Dawley; Spiro Compounds; Time Factors

1994
Quantification of diarrhetic shellfish toxins and identification of novel protein phosphatase inhibitors in marine phytoplankton and mussels.
    Toxicon : official journal of the International Society on Toxinology, 1993, Volume: 31, Issue:1

    Topics: Animals; Bivalvia; Chromatography, Liquid; Diarrhea; Ethers, Cyclic; Marine Toxins; Okadaic Acid; Phosphoprotein Phosphatases; Phytoplankton; Protein Phosphatase 1; Pyrans; Rabbits

1993
Liquid chromatographic determination of okadaic acid and dinophysistoxin-1 in shellfish after derivatization with 9-chloromethylanthracene.
    Journal of chromatography. A, 1996, Jan-19, Volume: 721, Issue:2

    Topics: Animals; Anthracenes; Bivalvia; Chromatography, Liquid; Diarrhea; Ethers, Cyclic; Indicators and Reagents; Marine Toxins; Okadaic Acid; Pyrans; Shellfish

1996
Simultaneous occurrence of diarrhetic and paralytic shellfish poisoning toxins in Spanish mussels in 1993.
    Natural toxins, 1996, Volume: 4, Issue:2

    Topics: Animals; Aquaculture; Bivalvia; Carcinogens; Chromatography, High Pressure Liquid; Diarrhea; Dinoflagellida; Electrophoresis, Capillary; Gas Chromatography-Mass Spectrometry; Marine Toxins; Okadaic Acid; Paralysis; Pyrans; Shellfish Poisoning; Spain; Structure-Activity Relationship

1996
Detection of diarrhoetic shellfish toxins in mussels from Italy by ionspray liquid chromatography-mass spectrometry.
    Toxicon : official journal of the International Society on Toxinology, 1995, Volume: 33, Issue:12

    Topics: Animals; Bivalvia; Carcinogens; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dinoflagellida; Fish Venoms; Italy; Marine Toxins; Mass Spectrometry; Okadaic Acid; Pyrans; Reference Standards; Shellfish

1995
The toxin of diarrheic shellfish poisoning, okadaic acid, increases intestinal epithelial paracellular permeability.
    Gastroenterology, 1997, Volume: 112, Issue:1

    Topics: Cell Membrane Permeability; Cells, Cultured; Electric Impedance; Enzyme Inhibitors; Gap Junctions; Humans; Intestinal Mucosa; Marine Toxins; Membrane Glycoproteins; Okadaic Acid; Phosphorylation; Pyrans

1997
Fluorimetric determination of diarrhetic shellfish toxins in scallops and mussels by high-performance liquid chromatography.
    Journal of chromatography. A, 1996, Apr-05, Volume: 729, Issue:1-2

    Topics: Animals; Bivalvia; Chromatography, High Pressure Liquid; Diarrhea; Digestive System; Indicators and Reagents; Marine Toxins; Okadaic Acid; Pyrans; Shellfish; Spectrometry, Fluorescence

1996
Automatic high-performance liquid chromatographic method for the determination of diarrhetic shellfish poison.
    Journal of chromatography. A, 1996, Apr-05, Volume: 729, Issue:1-2

    Topics: Animals; Bivalvia; Chromatography, High Pressure Liquid; Diarrhea; Digestive System; Indicators and Reagents; Marine Toxins; Okadaic Acid; Pyrans; Specimen Handling; Spectrometry, Fluorescence

1996
Optimization of sample cleanup procedure for determination of diarrhoeic shellfish poisoning toxins by use of experimental design.
    Journal of chromatography. A, 1997, Mar-14, Volume: 764, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dinoflagellida; Marine Toxins; Mice; Okadaic Acid; Pyrans; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence

1997
Comparison of a protein phosphatase inhibition assay, HPLC assay and enzyme-linked immunosorbent assay with the mouse bioassay for the detection of diarrhetic shellfish poisoning toxins in European shellfish.
    International journal of food microbiology, 1997, Apr-29, Volume: 36, Issue:1

    Topics: Animals; Biological Assay; Chromatography, High Pressure Liquid; Colorimetry; Diarrhea; Enzyme-Linked Immunosorbent Assay; Europe; Foodborne Diseases; Humans; Liver; Marine Toxins; Mice; Mice, Inbred BALB C; Okadaic Acid; Pancreas; Phosphoprotein Phosphatases; Protein Phosphatase 1; Pyrans; Sensitivity and Specificity; Shellfish; United Kingdom

1997
Improvement on sample clean-up for high-performance liquid chromatographic-fluorimetric determination of diarrhetic shellfish toxins using 1-bromoacetylpyrene.
    Journal of chromatography. A, 1998, Jan-09, Volume: 793, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Diarrhea; Fluorescent Dyes; Foodborne Diseases; Marine Toxins; Mollusca; Okadaic Acid; Pyrans; Pyrenes; Reproducibility of Results; Sensitivity and Specificity; Shellfish; Spectrometry, Fluorescence

1998
Toxin and subunit specificity of blocking affinity of three peptide toxins for heteromultimeric, voltage-gated potassium channels expressed in Xenopus oocytes.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 285, Issue:3

    Topics: Animals; Elapid Venoms; Electrophysiology; Female; Okadaic Acid; Oocytes; Potassium Channels; Pyrans; Scorpion Venoms; Toxins, Biological; Xenopus laevis

1998
Oral toxicity in mice of algal toxins from the diarrheic shellfish toxin (DST) complex and associated toxins.
    Journal of natural toxins, 1998, Volume: 7, Issue:2

    Topics: Administration, Oral; Animals; Bivalvia; Dinoflagellida; Injections, Intraperitoneal; Intestines; Jejunum; Liver; Marine Toxins; Mice; Norway; Okadaic Acid; Pyrans; Rats; Shellfish

1998
Sensitive detection of apoptogenic toxins in suspension cultures of rat and salmon hepatocytes.
    Toxicon : official journal of the International Society on Toxinology, 1998, Volume: 36, Issue:8

    Topics: Animals; Apoptosis; Cell Aggregation; Cells, Cultured; Eukaryota; Liver; Marine Toxins; Microcystins; Okadaic Acid; Oxazoles; Peptides, Cyclic; Pyrans; Rats

1998
Direct evidence of transformation of dinophysistoxin-1 to 7-O-acyl-dinophysistoxin-1 (dinophysistoxin-3) in the scallop Patinopecten yessoensis.
    Toxicon : official journal of the International Society on Toxinology, 1999, Volume: 37, Issue:1

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Dinoflagellida; Exocrine Glands; Hydrolysis; Indicators and Reagents; Marine Toxins; Mass Spectrometry; Mollusca; Okadaic Acid; Pyrans; Spectrometry, Fluorescence

1999
Evaluation of the use of two human cell lines for okadaic acid and DTX-1 determination by cytotoxicity assays and damage characterization.
    Natural toxins, 1998, Volume: 6, Issue:5

    Topics: Apoptosis; Caco-2 Cells; Cell Nucleus; Cell Survival; Coloring Agents; Cytoskeleton; Epithelial Cells; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inhibitory Concentration 50; Laryngeal Neoplasms; Marine Toxins; Neutral Red; Okadaic Acid; Pyrans; Tubulin; Tumor Cells, Cultured

1998
Development of an ultrasensitive immunoassay for rapid measurement of okadaic acid and its isomers.
    Analytical chemistry, 1999, Oct-01, Volume: 71, Issue:19

    Topics: Animals; Bivalvia; Calibration; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Isomerism; Okadaic Acid; Pyrans; Sensitivity and Specificity; Water

1999
Further studies on the analysis of DSP toxin profiles in galician mussels.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:2

    Topics: Animals; Bivalvia; Chromatography, Liquid; Mass Spectrometry; Okadaic Acid; Pyrans; Spectrometry, Fluorescence

1999
Liquid chromatography-electrospray ionization mass spectrometry of the diarrhetic shellfish-poisoning toxins okadaic acid, dinophysistoxin-1 and pectenotoxin-6 in bivalves.
    Journal of chromatography. A, 2000, Apr-07, Volume: 874, Issue:2

    Topics: Animals; Bivalvia; Chromatography, Liquid; Diarrhea; Furans; Hydrolysis; Macrolides; Mass Spectrometry; Mollusk Venoms; Okadaic Acid; Pyrans; Reference Standards; Toxins, Biological

2000
Development and validation of a high-performance liquid chromatographic method using fluorimetric detection for the determination of the diarrhetic shellfish poisoning toxin okadaic acid without chlorinated solvents.
    Journal of chromatography. A, 2000, Apr-21, Volume: 876, Issue:1-2

    Topics: Calibration; Chlorine Compounds; Chromatography, High Pressure Liquid; Diarrhea; Fluorometry; Humans; Mollusk Venoms; Okadaic Acid; Pyrans; Quality Control; Reference Standards; Reproducibility of Results; Shellfish; Solvents

2000
Detection of diarrhetic shellfish poisoning toxins from tropical shellfish using liquid chromatography-selected reaction monitoring mass spectrometry.
    Natural toxins, 1999, Volume: 7, Issue:6

    Topics: Animals; Bivalvia; Chromatography; Okadaic Acid; Pyrans; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

1999
Methodological improvement of the protein phosphatase inhibition assay for the detection of okadaic acid in mussels.
    Natural toxins, 1999, Volume: 7, Issue:6

    Topics: Animals; Biological Assay; Bivalvia; Environmental Monitoring; Enzyme Inhibitors; Mice; Okadaic Acid; Phosphoprotein Phosphatases; Pyrans; Reproducibility of Results; Sensitivity and Specificity

1999
Comparison of dinophysistoxin-1 and esterified dinophysistoxin-1 (dinophysistoxin-3) contents in the scallop Patinopecten yessoensis and the mussel Mytilus galloprovincialis.
    Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Esterification; Mollusca; Okadaic Acid; Pyrans; Species Specificity; Spectrometry, Fluorescence

2001
Toxin composition of the toxic dinoflagellate Prorocentrum lima isolated from different locations along the Galician coast (NW Spain).
    Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:10

    Topics: Animals; Chromatography, High Pressure Liquid; Cluster Analysis; Dinoflagellida; Enzyme Inhibitors; Esters; Fluorometry; Foodborne Diseases; Marine Toxins; Okadaic Acid; Pyrans; Spain; Statistics as Topic

2001
Survey of the distribution of red tide toxins (okadaic acid and dinophytoxin-1) in the Dalian Bay sea area of China by micellar electrokinetic capillary chromatography.
    Electrophoresis, 2001, Volume: 22, Issue:16

    Topics: Animals; Bivalvia; China; Chromatography, Micellar Electrokinetic Capillary; Food Contamination; Marine Toxins; Molecular Structure; Mollusca; Oceans and Seas; Okadaic Acid; Pyrans; Shellfish

2001
Isolation of Prorocentrum lima (Syn. Exuviaella lima) and diarrhetic shellfish poisoning (DSP) risk assessment in the Gulf of California, Mexico.
    Toxicon : official journal of the International Society on Toxinology, 2002, Volume: 40, Issue:8

    Topics: Animals; Chromatography, Thin Layer; Ciguatera Poisoning; Ciguatoxins; Diarrhea; Dinoflagellida; Foodborne Diseases; Mexico; Mice; Okadaic Acid; Pyrans; Risk Assessment; Shellfish

2002
New okadaic acid analogues from the marine sponge Merriamum oxeato and their effect on mitosis.
    Journal of natural products, 2003, Volume: 66, Issue:6

    Topics: Animals; Breast Neoplasms; British Columbia; DNA Damage; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Flow Cytometry; G2 Phase; Humans; Inhibitory Concentration 50; Mitosis; Molecular Structure; Okadaic Acid; Phosphoprotein Phosphatases; Porifera; Pyrans; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
Activity-dependent regulation of the potassium channel subunits Kv1.1 and Kv3.1.
    The Journal of comparative neurology, 2004, Feb-23, Volume: 470, Issue:1

    Topics: Animals; Animals, Newborn; Brain Stem; Cell Count; Chickens; Cochlea; Denervation; Densitometry; Functional Laterality; Immunohistochemistry; In Vitro Techniques; Kv1.1 Potassium Channel; Membrane Potentials; Neural Conduction; Neurons; Neuropeptides; Okadaic Acid; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Pyrans; Shaw Potassium Channels; Time Factors

2004
Biochemical characterization and inhibitory effects of dinophysistoxin-1, okadaic acid and microcystine 1-r on protein phosphatase 2a purified from the mussel Mytilus chilensis.
    Biological research, 2000, Volume: 33, Issue:3-4

    Topics: Animals; Bivalvia; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Marine Toxins; Microcystins; Okadaic Acid; Peptides, Cyclic; Phosphoprotein Phosphatases; Protein Phosphatase 2; Pyrans

2000
Morphology, toxin composition and pigment content of Prorocentrum lima strains isolated from a coastal lagoon in southern UK.
    Toxicon : official journal of the International Society on Toxinology, 2005, Volume: 45, Issue:5

    Topics: Animals; Chromatography, Liquid; Dinoflagellida; England; Marine Toxins; Mass Spectrometry; Microscopy, Electron, Scanning; Okadaic Acid; Pigments, Biological; Pyrans; Seawater; Species Specificity

2005
Confirmation of okadaic acid, dinophysistoxin-1 and dinophysistoxin-2 in shellfish as their anthrylmethyl derivatives using UV radiation.
    Journal of chromatography. A, 2005, Jul-08, Volume: 1080, Issue:2

    Topics: Animals; Anthracenes; Bivalvia; Chromatography, Liquid; Dinoflagellida; Marine Toxins; Mass Spectrometry; Okadaic Acid; Pyrans; Sensitivity and Specificity; Spectrometry, Fluorescence; Ultraviolet Rays

2005
Metabolic transformation of dinophysistoxin-3 into dinophysistoxin-1 causes human intoxication by consumption of O-acyl-derivatives dinophysistoxins contaminated shellfish.
    The Journal of toxicological sciences, 2005, Volume: 30, Issue:4

    Topics: Abdominal Pain; Adolescent; Adult; Biotransformation; Chile; Diarrhea; Feces; Food Contamination; Gastric Mucosa; Humans; Marine Toxins; Mass Spectrometry; Mytilus edulis; Okadaic Acid; Pyrans; Shellfish; Shellfish Poisoning; Vomiting

2005
Isolation and identification of a cis-C8-diol-ester of okadaic acid from Dinophysis acuta in New Zealand.
    Toxicon : official journal of the International Society on Toxinology, 2006, Volume: 48, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dinoflagellida; Esterification; Furans; Hepatopancreas; Hydrolysis; Macrolides; Magnetic Resonance Spectroscopy; Marine Toxins; Molecular Structure; Okadaic Acid; Pyrans; Spectrometry, Mass, Electrospray Ionization

2006
Detection of the marine toxin okadaic acid in mussels during a diarrhetic shellfish poisoning (DSP) episode in Thermaikos Gulf, Greece, using biological, chemical and immunological methods.
    The Science of the total environment, 2006, Aug-01, Volume: 366, Issue:2-3

    Topics: Animals; Chromatography, High Pressure Liquid; Diarrhea; Environmental Monitoring; Enzyme-Linked Immunosorbent Assay; Food Contamination; Greece; Marine Toxins; Mice; Mytilus; Okadaic Acid; Pyrans; Shellfish Poisoning

2006
Clarification of the C-35 stereochemistries of dinophysistoxin-1 and dinophysistoxin-2 and its consequences for binding to protein phosphatase.
    Chemical research in toxicology, 2007, Volume: 20, Issue:6

    Topics: Animals; Carbon Isotopes; Computational Biology; Dinoflagellida; Magnetic Resonance Spectroscopy; Marine Toxins; Models, Molecular; Molecular Conformation; Nitrogen Isotopes; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Protein Phosphatase 2; Pyrans; Solvents

2007
Characterization of fatty acid esters of okadaic acid and related toxins in blue mussels (Mytilus edulis) from Norway.
    Rapid communications in mass spectrometry : RCM, 2008, Volume: 22, Issue:8

    Topics: Animals; Environmental Monitoring; Esterification; Fatty Acids; Food Analysis; Marine Toxins; Mytilus edulis; Norway; Okadaic Acid; Pyrans; Shellfish; Spectrometry, Mass, Electrospray Ionization

2008
Removal of lipids and diarrhetic shellfish poisoning toxins from blue mussels (Mytilus edulis) during acid and alkaline isolation of proteins.
    Journal of agricultural and food chemistry, 2008, May-28, Volume: 56, Issue:10

    Topics: Animals; Calcium Chloride; Citric Acid; Dinoflagellida; Food Handling; Hydrogen-Ion Concentration; Lipids; Marine Toxins; Mytilus edulis; Okadaic Acid; Proteins; Pyrans

2008
Comparative study of the use of neuroblastoma cells (Neuro-2a) and neuroblastomaxglioma hybrid cells (NG108-15) for the toxic effect quantification of marine toxins.
    Toxicon : official journal of the International Society on Toxinology, 2008, Sep-15, Volume: 52, Issue:4

    Topics: Acrylamides; Animals; Cell Line, Tumor; Cnidarian Venoms; Dose-Response Relationship, Drug; Furans; Glioma; Hybrid Cells; Kainic Acid; Macrolides; Marine Toxins; Mice; Neuroblastoma; Okadaic Acid; Oxocins; Pyrans; Saxitoxin; Time Factors; Toxicity Tests

2008
Detection of okadaic acid and related esters in mussels during diarrhetic shellfish poisoning (DSP) episodes in Greece using the mouse bioassay, the PP2A inhibition assay and HPLC with fluorimetric detection.
    Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 53, Issue:2

    Topics: Animals; Biological Assay; Bivalvia; Chromatography, High Pressure Liquid; Diarrhea; Disease Outbreaks; Fluorometry; Foodborne Diseases; Greece; Humans; Mice; Okadaic Acid; Phosphoric Monoester Hydrolases; Pyrans; Shellfish Poisoning; Time Factors

2009
[Effects of different phosphorus sources on the growth and toxin production of Prorocentrum lima].
    Huan jing ke xue= Huanjing kexue, 2008, Volume: 29, Issue:10

    Topics: Alkaline Phosphatase; Animals; Dinoflagellida; Glycerophosphates; Marine Toxins; Okadaic Acid; Phosphates; Phosphorus; Pyrans

2008
Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast.
    Toxicon : official journal of the International Society on Toxinology, 2009, Volume: 54, Issue:2

    Topics: Animals; Chromatography, High Pressure Liquid; Dinoflagellida; Indicators and Reagents; Marine Toxins; Mass Spectrometry; Okadaic Acid; Portugal; Pyrans; Spectrometry, Mass, Electrospray Ionization

2009
Development of a monoclonal antibody binding okadaic acid and dinophysistoxins-1, -2 in proportion to their toxicity equivalence factors.
    Toxicon : official journal of the International Society on Toxinology, 2009, Sep-15, Volume: 54, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Biosensing Techniques; Bivalvia; Enzyme-Linked Immunosorbent Assay; Food Contamination; Marine Toxins; Mice; Mice, Inbred BALB C; Okadaic Acid; Pyrans

2009
Determination of okadaic acid, dinophysistoxin-1 and related esters in Greek mussels using HPLC with fluorometric detection, LC-MS/MS and mouse bioassay.
    Toxicon : official journal of the International Society on Toxinology, 2010, Apr-01, Volume: 55, Issue:4

    Topics: Animals; Biological Assay; Bivalvia; Chromatography, High Pressure Liquid; Greece; Limit of Detection; Mice; Okadaic Acid; Pyrans; Tandem Mass Spectrometry

2010
A structural basis for the reduced toxicity of dinophysistoxin-2.
    Chemical research in toxicology, 2009, Volume: 22, Issue:11

    Topics: Animals; Binding Sites; Crystallography, X-Ray; Marine Toxins; Mice; Molecular Conformation; Okadaic Acid; Protein Phosphatase 2; Pyrans; Stereoisomerism

2009
Development and single-laboratory validation of a pseudofunctional biosensor immunoassay for the detection of the okadaic acid group of toxins.
    Analytical chemistry, 2009, Dec-15, Volume: 81, Issue:24

    Topics: Animals; Biosensing Techniques; Chromatography, Liquid; Immunoassay; Marine Toxins; Okadaic Acid; Pyrans; Shellfish; Tandem Mass Spectrometry

2009
Effect of uncontrolled factors in a validated liquid chromatography-tandem mass spectrometry method question its use as a reference method for marine toxins: major causes for concern.
    Analytical chemistry, 2011, Aug-01, Volume: 83, Issue:15

    Topics: Chromatography, High Pressure Liquid; Marine Toxins; Okadaic Acid; Pyrans; Tandem Mass Spectrometry

2011
Tailored microarray platform for the detection of marine toxins.
    Environmental science & technology, 2011, Oct-15, Volume: 45, Issue:20

    Topics: Antigens, CD; Caco-2 Cells; Cell Adhesion Molecules; Gene Expression; Gene Expression Profiling; Humans; Marine Toxins; Okadaic Acid; Oligonucleotide Array Sequence Analysis; Pyrans; Reverse Transcriptase Polymerase Chain Reaction; Spiro Compounds; Transcription Factors; Tubulin

2011
Occurrence of diarrhetic shellfish poisoning (DSP) toxins in clams (Ruditapes decussatus) from Tunis north lagoon.
    Environmental monitoring and assessment, 2012, Volume: 184, Issue:8

    Topics: Animals; Bivalvia; Chromatography, Liquid; Dinoflagellida; Environmental Monitoring; Epidemiological Monitoring; Marine Toxins; Okadaic Acid; Pyrans; Shellfish Poisoning; Tandem Mass Spectrometry; Tunisia; Water Pollutants, Chemical

2012
Toxins in mussels (Mytilus galloprovincialis) associated with diarrhetic shellfish poisoning episodes in China.
    Toxicon : official journal of the International Society on Toxinology, 2012, Sep-01, Volume: 60, Issue:3

    Topics: Abdominal Pain; Alveolata; Animals; China; Diarrhea; Diet; Disease Outbreaks; Food Contamination; Humans; Marine Toxins; Mollusk Venoms; Mytilus; Okadaic Acid; Ostreidae; Oxocins; Pacific Ocean; Pectinidae; Pyrans; Seafood; Shellfish Poisoning

2012
[Simultaneous determination of okadaic acid, dinophysistoxin, pectenotoxin and yessotoxin in shellfish by liquid chromatography-tandem mass spectrometry].
    Se pu = Chinese journal of chromatography, 2012, Volume: 30, Issue:3

    Topics: Animals; Chromatography, Liquid; Furans; Macrolides; Mollusca; Mollusk Venoms; Okadaic Acid; Oxocins; Pyrans; Shellfish; Tandem Mass Spectrometry

2012
Transgenic quail as a model for research in the avian nervous system: a comparative study of the auditory brainstem.
    The Journal of comparative neurology, 2013, Jan-01, Volume: 521, Issue:1

    Topics: Animals; Animals, Genetically Modified; Animals, Newborn; Brain Stem; Chick Embryo; Cochlea; Coturnix; Electric Stimulation; Embryo, Nonmammalian; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Fluoxetine; Functional Laterality; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; In Vitro Techniques; Kv1.3 Potassium Channel; Lentivirus; Male; Membrane Potentials; Microtubule-Associated Proteins; Models, Animal; Neural Pathways; Neurons; Okadaic Acid; Patch-Clamp Techniques; Picrotoxin; Pyrans; Quinoxalines; Selective Serotonin Reuptake Inhibitors; Synapsins; Transgenes; Valine

2013
Production of monoclonal antibody and application in indirect competitive ELISA for detecting okadaic acid and dinophytoxin-1 in seafood.
    Environmental science and pollution research international, 2011, Volume: 19, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Cell Line; Enzyme-Linked Immunosorbent Assay; Food Analysis; Humans; Mice; Mice, Inbred BALB C; Okadaic Acid; Protein Binding; Pyrans; Seafood; Serum Albumin, Bovine; Water Pollutants, Chemical

2011
Simultaneous multiplexed stripping voltammetric monitoring of marine toxins in seafood based on distinguishable metal nanocluster-labeled molecular tags.
    Journal of agricultural and food chemistry, 2012, Sep-12, Volume: 60, Issue:36

    Topics: Adsorption; Animals; Cadmium; Copper; Food Contamination; Immunoassay; Limit of Detection; Marine Toxins; Metal Nanoparticles; Okadaic Acid; Oxocins; Pyrans; Seafood

2012
First detection and seasonal variation of lipophilic toxins okadaic acid, dinophysistoxin-1, and yessotoxin in Korean gastropods.
    Journal of food protection, 2012, Volume: 75, Issue:11

    Topics: Animals; Consumer Product Safety; Food Contamination; Food Safety; Gastropoda; Humans; Mollusk Venoms; Okadaic Acid; Oxocins; Pyrans; Republic of Korea; Seasons; Shellfish; Species Specificity

2012
[Isolation and identification of shellfish toxins from contaminated blue mussel (Mytilus edulis) from the East China Sea].
    Wei sheng yan jiu = Journal of hygiene research, 2012, Volume: 41, Issue:5

    Topics: Animals; China; Chromatography, High Pressure Liquid; Food Contamination; Furans; Macrolides; Mytilus edulis; Oceans and Seas; Okadaic Acid; Pyrans; Shellfish

2012
Inhibition equivalency factors for dinophysistoxin-1 and dinophysistoxin-2 in protein phosphatase assays: applicability to the analysis of shellfish samples and comparison with LC-MS/MS.
    Journal of agricultural and food chemistry, 2013, Mar-13, Volume: 61, Issue:10

    Topics: Animals; Biological Assay; Bivalvia; Chromatography, High Pressure Liquid; Humans; Marine Toxins; Okadaic Acid; Protein Phosphatase 2; Pyrans; Shellfish; Tandem Mass Spectrometry

2013
Diarrhetic shellfish poisoning, Washington, USA, 2011.
    Emerging infectious diseases, 2013, Volume: 19, Issue:8

    Topics: Animals; Aquaculture; Child, Preschool; Harmful Algal Bloom; Humans; Middle Aged; Mytilus; Okadaic Acid; Pyrans; Shellfish Poisoning; Washington

2013
First report of the toxin profile of Dinophysis sacculus Stein from LC-MS analysis of laboratory cultures.
    Toxicon : official journal of the International Society on Toxinology, 2013, Dec-15, Volume: 76

    Topics: Chromatography, Liquid; Dinoflagellida; Environmental Monitoring; Humans; Marine Toxins; Mass Spectrometry; Okadaic Acid; Pyrans; Shellfish Poisoning; Spain

2013
Graphene based pipette tip solid phase extraction of marine toxins in shellfish muscle followed by UPLC-MS/MS analysis.
    Talanta, 2013, Nov-15, Volume: 116

    Topics: Adsorption; Animals; Bivalvia; Chromatography, High Pressure Liquid; Furans; Graphite; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Toxins; Mollusk Venoms; Muscles; Okadaic Acid; Oxocins; Pyrans; Reproducibility of Results; Sensitivity and Specificity; Shellfish; Solid Phase Extraction; Spiro Compounds; Tandem Mass Spectrometry

2013
Experimental basis for the high oral toxicity of dinophysistoxin 1: a comparative study of DSP.
    Toxins, 2014, Jan-03, Volume: 6, Issue:1

    Topics: Caco-2 Cells; Humans; Intestinal Absorption; Lethal Dose 50; Marine Toxins; Microscopy, Confocal; Okadaic Acid; Pyrans

2014
Contamination of commercially available seafood by key diarrhetic shellfish poisons along the coast of China.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:2

    Topics: Animals; China; Disease Outbreaks; Enzyme-Linked Immunosorbent Assay; Food Contamination; Marine Toxins; Oceans and Seas; Okadaic Acid; Pyrans; Shellfish; Shellfish Poisoning; Species Specificity

2015
Comparative analysis of the cytotoxic effects of okadaic acid-group toxins on human intestinal cell lines.
    Marine drugs, 2014, Aug-21, Volume: 12, Issue:8

    Topics: Apoptosis; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; DNA Damage; HT29 Cells; Humans; Inflammation; Intestinal Mucosa; Intestines; Okadaic Acid; Pyrans; Toxins, Biological

2014
Evaluation of okadaic acid, dinophysistoxin-1 and dinophysistoxin-2 toxicity on Neuro-2a, NG108-15 and MCF-7 cell lines.
    Toxicology in vitro : an international journal published in association with BIBRA, 2015, Volume: 29, Issue:1

    Topics: Cell Line; Dose-Response Relationship, Drug; Humans; Marine Toxins; MCF-7 Cells; Okadaic Acid; Pyrans

2015
Effect of seawater salinity on pore-size distribution on a poly(styrene)-based HP20 resin and its adsorption of diarrhetic shellfish toxins.
    Journal of chromatography. A, 2014, Dec-19, Volume: 1373

    Topics: Adsorption; Alveolata; Chromatography, High Pressure Liquid; Okadaic Acid; Polystyrenes; Porosity; Pyrans; Salinity; Seawater

2014
Acute cardiotoxicity evaluation of the marine biotoxins OA, DTX-1 and YTX.
    Toxins, 2015, Mar-27, Volume: 7, Issue:4

    Topics: Animals; Cardiotoxicity; CHO Cells; Cricetinae; Cricetulus; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Mollusk Venoms; Natriuretic Peptide, Brain; Okadaic Acid; Oxocins; Pyrans; Rats; Rats, Sprague-Dawley; Troponin I; Troponin T

2015
Diarrhetic effect of okadaic acid could be related with its neuronal action: Changes in neuropeptide Y.
    Toxicology letters, 2015, Sep-02, Volume: 237, Issue:2

    Topics: Caco-2 Cells; Cell Line, Tumor; Cell Survival; Diarrhea; Electric Impedance; Humans; Neuroblastoma; Neurons; Neuropeptide Y; Okadaic Acid; Pyrans

2015
Generation of a panel of high affinity antibodies and development of a biosensor-based immunoassay for the detection of okadaic acid in shellfish.
    Toxicon : official journal of the International Society on Toxinology, 2015, Volume: 103

    Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Biological Assay; Biosensing Techniques; Bivalvia; Hydrogen-Ion Concentration; Immunoassay; Marine Toxins; Mice; Mice, Inbred BALB C; Okadaic Acid; Pyrans; Sensitivity and Specificity; Shellfish; Surface Plasmon Resonance

2015
Analysis of diarrhetic shellfish poisoning toxins and pectenotoxin-2 in the bottlenose dolphin (Tursiops truncatus) by liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. A, 2015, Oct-16, Volume: 1416

    Topics: Animals; Bottle-Nosed Dolphin; Chromatography, Liquid; Diarrhea; Furans; Macrolides; Marine Toxins; Okadaic Acid; Pyrans; Shellfish Poisoning; Solid Phase Extraction; Tandem Mass Spectrometry

2015
Detection of Dinophysistoxin-1 in Clonal Culture of Marine Dinoflagellate Prorocentrum foraminosum (Faust M.A., 1993) from the Sea of Japan.
    Toxins, 2015, Sep-28, Volume: 7, Issue:10

    Topics: Chromatography, High Pressure Liquid; Clone Cells; Culture Media; Dinoflagellida; Environmental Monitoring; Harmful Algal Bloom; Mass Spectrometry; Oceans and Seas; Okadaic Acid; Pyrans; Russia; Seawater; Species Specificity

2015
Assimilation, Accumulation, and Metabolism of Dinophysistoxins (DTXs) and Pectenotoxins (PTXs) in the Several Tissues of Japanese Scallop Patinopecten yessoensis.
    Toxins, 2015, Dec-01, Volume: 7, Issue:12

    Topics: Animals; Dinoflagellida; Feces; Food Chain; Furans; Gastrointestinal Tract; Gills; Gonads; Macrolides; Muscles; Okadaic Acid; Pectinidae; Pyrans; Seawater; Water Pollutants

2015
[Validation Study for Analytical Method of Diarrhetic Shellfish Poisons in 9 Kinds of Shellfish].
    Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan, 2016, Volume: 57, Issue:1

    Topics: Animals; Chromatography, Liquid; Food Contamination; Methanol; Okadaic Acid; Poisons; Pyrans; Reproducibility of Results; Shellfish; Shellfish Poisoning; Sodium Hydroxide; Solutions; Tandem Mass Spectrometry

2016
Absolute Quantification of Lipophilic Shellfish Toxins by Quantitative Nuclear Magnetic Resonance Using Removable Internal Reference Substance with SI Traceability.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2016, Volume: 32, Issue:7

    Topics: Calibration; Dinoflagellida; Magnetic Resonance Spectroscopy; Marine Toxins; Okadaic Acid; Pyrans; Reference Standards; Sensitivity and Specificity; Shellfish

2016
Development of Certified Reference Materials for Diarrhetic Shellfish Poisoning Toxins, Part 1: Calibration Solutions.
    Journal of AOAC International, 2016, Volume: 99, Issue:5

    Topics: Animals; Calibration; Chromatography, Liquid; Diarrhea; Humans; Magnetic Resonance Spectroscopy; Marine Toxins; Okadaic Acid; Pyrans; Reference Standards; Shellfish; Shellfish Poisoning; Tandem Mass Spectrometry

2016
Development of Certified Reference Materials for Diarrhetic Shellfish Poisoning Toxins, Part 2: Shellfish Matrix Materials.
    Journal of AOAC International, 2016, Volume: 99, Issue:5

    Topics: Animals; Calibration; Chromatography, Liquid; Diarrhea; Humans; Marine Toxins; Molecular Conformation; Okadaic Acid; Pyrans; Reference Standards; Shellfish; Shellfish Poisoning; Tandem Mass Spectrometry

2016
A mussel tissue certified reference material for multiple phycotoxins. Part 4: certification.
    Analytical and bioanalytical chemistry, 2017, Volume: 409, Issue:1

    Topics: Animals; Chromatography, Liquid; Freeze Drying; Furans; Kainic Acid; Macrolides; Marine Toxins; Mass Spectrometry; Mollusk Venoms; Mytilus edulis; Okadaic Acid; Oxocins; Pyrans; Reference Standards; Seafood; Spiro Compounds

2017
Sublethal doses of dinophysistoxin-1 and okadaic acid stimulate secretion of inflammatory factors on innate immune cells: Negative health consequences.
    Toxicon : official journal of the International Society on Toxinology, 2017, Volume: 126

    Topics: Animals; Chemokines; Cytokines; Enzyme-Linked Immunosorbent Assay; Immunity, Innate; Interleukin-6; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Okadaic Acid; Pyrans; Toxicity Tests; Tumor Necrosis Factor-alpha

2017
Sulfated diesters of okadaic acid and DTX-1: Self-protective precursors of diarrhetic shellfish poisoning (DSP) toxins.
    Harmful algae, 2017, Volume: 63

    Topics: Animals; Dinoflagellida; Marine Toxins; Okadaic Acid; Pyrans; Shellfish Poisoning

2017
Limaol: A Polyketide from the Benthic Marine Dinoflagellate Prorocentrum lima.
    Journal of natural products, 2017, 05-26, Volume: 80, Issue:5

    Topics: Animals; Cell Line, Tumor; Dinoflagellida; Magnetic Resonance Spectroscopy; Marine Toxins; Molecular Structure; Okadaic Acid; Polyketides; Pyrans; Spiro Compounds

2017
Occurrence of marine algal toxins in oyster and phytoplankton samples in Daya Bay, South China Sea.
    Chemosphere, 2017, Volume: 183

    Topics: Animals; Bays; China; Chromatography, Liquid; Dinoflagellida; Environmental Monitoring; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Kainic Acid; Marine Toxins; Okadaic Acid; Ostreidae; Phytoplankton; Pyrans; Tandem Mass Spectrometry; Water Pollutants, Chemical

2017
Lipophilic marine toxins discovered in the Bohai Sea using high performance liquid chromatography coupled with tandem mass spectrometry.
    Chemosphere, 2017, Volume: 183

    Topics: Animals; China; Chromatography, High Pressure Liquid; Dinoflagellida; Furans; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Hydrophobic and Hydrophilic Interactions; Imines; Macrolides; Marine Toxins; Mollusk Venoms; Okadaic Acid; Oxocins; Phytoplankton; Pyrans; Seafood; Spiro Compounds; Tandem Mass Spectrometry

2017
Embryotoxic effects of dissolved okadaic acid on the development of Longfin yellowtail Seriola rivoliana.
    Aquatic toxicology (Amsterdam, Netherlands), 2017, Volume: 190

    Topics: Animals; Climate Change; Dinoflagellida; Embryo, Nonmammalian; Embryonic Development; Enzyme Inhibitors; Fishes; Harmful Algal Bloom; Okadaic Acid; Pyrans; Water Pollutants, Chemical

2017
Whole genome mRNA transcriptomics analysis reveals different modes of action of the diarrheic shellfish poisons okadaic acid and dinophysis toxin-1 versus azaspiracid-1 in Caco-2 cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 46

    Topics: Caco-2 Cells; Cell Survival; Gene Expression Profiling; Gene Expression Regulation; Genome; Humans; Marine Toxins; Okadaic Acid; Pyrans; RNA, Messenger; Spiro Compounds

2018
Accumulation and Tissue Distribution of Dinophysitoxin-1 and Dinophysitoxin-3 in the Mussel Crenomytilus grayanus Feeding on the Benthic Dinoflagellate Prorocentrum foraminosum.
    Marine drugs, 2017, Oct-24, Volume: 15, Issue:10

    Topics: Animals; Diarrhea; Dinoflagellida; Gastrointestinal Tract; Gills; Humans; Japan; Kidney; Marine Toxins; Mutagenicity Tests; Mytilidae; Oceans and Seas; Okadaic Acid; Pyrans; Seafood; Seawater; Tissue Distribution

2017
Interlaboratory comparison of liquid chromatography-tandem mass spectrometry quantification of diarrhetic shellfish toxins in scallop midgut glands.
    Food chemistry, 2018, Jun-30, Volume: 252

    Topics: Animals; Chromatography, Liquid; Intestines; Marine Toxins; Okadaic Acid; Pectinidae; Pyrans; Reproducibility of Results; Shellfish; Shellfish Poisoning; Tandem Mass Spectrometry

2018
Comparative toxicity of dinophysistoxin-1 and okadaic acid in mice.
    The Journal of veterinary medical science, 2018, Apr-18, Volume: 80, Issue:4

    Topics: Animals; Biological Assay; Bivalvia; Dose-Response Relationship, Drug; Lethal Dose 50; Mice; Okadaic Acid; Pyrans; Toxicity Tests

2018
Lipophilic marine biotoxins SERS sensing in solutions and in mussel tissue.
    Talanta, 2018, Sep-01, Volume: 187

    Topics: Animals; Bivalvia; Hydrophobic and Hydrophilic Interactions; Marine Toxins; Mollusk Venoms; Okadaic Acid; Oxocins; Pyrans; Spectrum Analysis, Raman; Surface Properties

2018
Effect of Suspended Particulate Matter on the Accumulation of Dissolved Diarrhetic Shellfish Toxins by Mussels (
    Toxins, 2018, 07-03, Volume: 10, Issue:7

    Topics: Animals; Marine Toxins; Microalgae; Mytilus; Okadaic Acid; Particulate Matter; Pyrans

2018
Toxic Action Reevaluation of Okadaic Acid, Dinophysistoxin-1 and Dinophysistoxin-2: Toxicity Equivalency Factors Based on the Oral Toxicity Study.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 49, Issue:2

    Topics: Administration, Oral; Animals; Body Weight; Chromatography, High Pressure Liquid; Female; Heart; Intestine, Small; Liver; Mice; Myocardium; Okadaic Acid; Protein Phosphatase 2; Pyrans; Stomach; Tandem Mass Spectrometry; Toxicity Tests

2018
Anatomical Distribution of Diarrhetic Shellfish Toxins (DSTs) in the Japanese Scallop
    Toxins, 2018, 09-27, Volume: 10, Issue:10

    Topics: Animals; Chromatography, Liquid; Gastrointestinal Tract; Gills; Gonads; Marine Toxins; Muscle, Skeletal; Mytilus edulis; Okadaic Acid; Pectinidae; Pyrans; Shellfish Poisoning; Tandem Mass Spectrometry

2018
    Toxins, 2018, 09-28, Volume: 10, Issue:10

    Topics: Animals; Bivalvia; Dinoflagellida; Environmental Monitoring; Food Contamination; Marine Toxins; Okadaic Acid; Pyrans; Scotland; Seafood; Shellfish Poisoning; Water Pollutants

2018
A Long-Term Time Series of
    Toxins, 2019, 02-01, Volume: 11, Issue:2

    Topics: Animals; Dinoflagellida; Environmental Monitoring; Furans; Harmful Algal Bloom; Macrolides; Marine Toxins; New Zealand; Okadaic Acid; Perna; Pyrans; Shellfish; Shellfish Poisoning; Water Pollutants

2019
Recyclable magnetic covalent organic framework for the extraction of marine biotoxins.
    Nanoscale, 2019, Mar-28, Volume: 11, Issue:13

    Topics: 2-Propanol; Adsorption; Dopamine; Ferrosoferric Oxide; Kinetics; Magnetics; Metal-Organic Frameworks; Okadaic Acid; Pyrans; Solid Phase Extraction

2019
Contamination status of lipophilic marine toxins in shellfish samples from the Bohai Sea, China.
    Environmental pollution (Barking, Essex : 1987), 2019, Volume: 249

    Topics: Animals; Bivalvia; China; Chromatography, Liquid; Dinoflagellida; Furans; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Toxins; Mollusk Venoms; Okadaic Acid; Ostreidae; Oxocins; Pyrans; Seafood; Shellfish; Spiro Compounds; Tandem Mass Spectrometry; Water Pollutants, Chemical

2019
Characterization of scallop midgut gland certified reference material for quantification of diarrhetic shellfish toxins.
    Food chemistry, 2019, Nov-15, Volume: 298

    Topics: Animals; Calibration; Chromatography, Liquid; Diarrhea; Humans; Intestines; Marine Toxins; Okadaic Acid; Pectinidae; Pyrans; Reference Standards; Shellfish; Shellfish Poisoning; Tandem Mass Spectrometry

2019
Morphology and Phylogenetics of Benthic
    Toxins, 2019, 09-30, Volume: 11, Issue:10

    Topics: Australia; Dinoflagellida; Marine Toxins; Okadaic Acid; Phylogeny; Pyrans; Tropical Climate

2019
Distribution Characteristics and Environmental Control Factors of Lipophilic Marine Algal Toxins in Changjiang Estuary and the Adjacent East China Sea.
    Toxins, 2019, 10-12, Volume: 11, Issue:10

    Topics: China; Dinoflagellida; Environmental Monitoring; Estuaries; Furans; Heterocyclic Compounds, 3-Ring; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Toxins; Oceans and Seas; Okadaic Acid; Phytoplankton; Pyrans; Seawater; Water Pollutants

2019
Lipophilic Toxins in Galicia (NW Spain) between 2014 and 2017: Incidence on the Main Molluscan Species and Analysis of the Monitoring Efficiency.
    Toxins, 2019, 10-22, Volume: 11, Issue:10

    Topics: Animals; Biological Monitoring; Bivalvia; Food Contamination; Furans; Macrolides; Marine Toxins; Mollusk Venoms; Okadaic Acid; Oxocins; Pyrans; Spain

2019
Occurrence and distribution of lipophilic phycotoxins in a subtropical bay of the South China Sea.
    Chemosphere, 2020, Volume: 243

    Topics: Animals; Bays; China; Chromatography, Liquid; Environmental Monitoring; Furans; Heterocyclic Compounds, 3-Ring; Humans; Hydrocarbons, Cyclic; Imines; Macrolides; Marine Toxins; Mollusk Venoms; Okadaic Acid; Oxocins; Phytoplankton; Pyrans; Seafood; Seawater; Shellfish; Spiro Compounds; Tandem Mass Spectrometry

2020
Toxins of Okadaic Acid-Group Increase Malignant Properties in Cells of Colon Cancer.
    Toxins, 2020, 03-13, Volume: 12, Issue:3

    Topics: Animals; Carcinogens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colonic Neoplasms; Focal Adhesion Kinase 1; Humans; Inhibitory Concentration 50; Okadaic Acid; Protein Phosphatase 2

2020
Benchmark dose analyses of γH2AX and pH3 endpoints for quantitative comparison of in vitro genotoxicity potential of lipophilic phycotoxins.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2020, Volume: 852

    Topics: Benchmarking; Biomarkers; Cell Line, Transformed; Cell Proliferation; DNA Damage; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Histones; Humans; Hydrophobic and Hydrophilic Interactions; Mitosis; Mutagenicity Tests; Mutagens; Okadaic Acid; Phosphorylation; Pyrans; Software

2020
Aqueous photodegradation of okadaic acid and dinophysistoxin-1: Persistence, kinetics, photoproducts, pathways, and toxicity evaluation.
    The Science of the total environment, 2020, Nov-15, Volume: 743

    Topics: Ecosystem; Humans; Kinetics; Marine Toxins; Okadaic Acid; Photolysis; Pyrans

2020
Response of fatty acids and lipid metabolism enzymes during accumulation, depuration and esterification of diarrhetic shellfish toxins in mussels (Mytilus galloprovincialis).
    Ecotoxicology and environmental safety, 2020, Dec-15, Volume: 206

    Topics: Animals; Dinoflagellida; Esterification; Esters; Fatty Acids; Food Chain; Lipid Metabolism; Marine Toxins; Microalgae; Mytilus; Okadaic Acid; Seafood; Shellfish; Shellfish Poisoning

2020
Risk Assessment of Pectenotoxins in New Zealand Bivalve Molluscan Shellfish, 2009-2019.
    Toxins, 2020, 12-06, Volume: 12, Issue:12

    Topics: Animals; Bivalvia; Marine Toxins; New Zealand; Okadaic Acid; Phytoplankton; Risk Assessment; Shellfish; Shellfish Poisoning

2020
Differences in Toxic Response Induced by Three Variants of the Diarrheic Shellfish Poisoning Phycotoxins in Human Intestinal Epithelial Caco-2 Cells.
    Toxins, 2020, 12-08, Volume: 12, Issue:12

    Topics: Animals; Caco-2 Cells; Cell Survival; Dose-Response Relationship, Drug; Humans; Intestinal Mucosa; Marine Toxins; Okadaic Acid; Shellfish Poisoning

2020
Improved Isolation Procedures for Okadaic Acid Group Toxins from Shellfish (
    Marine drugs, 2020, Dec-16, Volume: 18, Issue:12

    Topics: Animals; Biomass; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Marine Toxins; Microalgae; Mytilus edulis; Okadaic Acid; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry

2020
DSP Toxin Distribution across Organs in Mice after Acute Oral Administration.
    Marine drugs, 2021, Jan-08, Volume: 19, Issue:1

    Topics: Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Intestines; Marine Toxins; Mass Spectrometry; Mice; Mice, Inbred C57BL; Okadaic Acid; Shellfish; Shellfish Poisoning; Stomach; Tissue Distribution; Toxicokinetics

2021
Determination of lipophilic marine biotoxins by liquid chromatography-tandem mass spectrometry in five shellfish species from Washington State, USA.
    Journal of chromatography. A, 2021, Feb-22, Volume: 1639

    Topics: Alkalies; Animals; Chromatography, Liquid; Furans; Lipids; Macrolides; Marine Toxins; Methanol; Mollusk Venoms; Okadaic Acid; Oxocins; Shellfish; Spiro Compounds; Tandem Mass Spectrometry; Washington

2021
Simultaneous screening of multiple diarrhetic shellfish poisons with group-specific split aptamers and silver nanocluster beacon.
    Food chemistry, 2023, Jun-01, Volume: 410

    Topics: Humans; Marine Toxins; Okadaic Acid; Poisons; Pyrans; Shellfish; Shellfish Poisoning; Silver

2023
    Marine drugs, 2023, Jan-19, Volume: 21, Issue:2

    Topics: Dinoflagellida; Estuaries; Humans; Marine Toxins; Okadaic Acid; Shellfish Poisoning

2023
Growth, Toxin Content and Production of Dinophysis Norvegica in Cultured Strains Isolated from Funka Bay (Japan).
    Toxins, 2023, 05-01, Volume: 15, Issue:5

    Topics: Bays; Ciliophora; Dinoflagellida; Japan; Marine Toxins; Okadaic Acid

2023
Okadaic Acid Is at Least as Toxic as Dinophysistoxin-1 after Repeated Administration to Mice by Gavage.
    Toxins, 2023, 09-23, Volume: 15, Issue:10

    Topics: Animals; Diarrhea; Humans; Lethal Dose 50; Mice; Okadaic Acid; Pyrans; Shellfish Poisoning

2023