Compounds > diminazene

diminazene and furamidine

diminazene has been researched along with furamidine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clercq, ED; Dann, O1
Brun, R; de Koning, HP; Gould, M; Kaiser, M; Koomen, GJ; Rodenko, B; van der Burg, AM; Wanner, MJ1
Anbazhagan, M; Boykin, DW; Brun, R; Gillingwater, K; Kumar, A; Tidwell, RR1
Maciejewska, D; Zołek, T1
Avery, VM; Barrett, M; Duffy, S; Giordani, F; Khalaf, AI; Scott, FJ; Suckling, CJ; Wong, PE1
Boykin, DW; Laughton, CA; Neidle, S; Nunn, CM; Tanious, F; Wilson, WD1
Agama, KK; Antony, S; Fisher, RJ; Marchand, C; Pommier, Y; Stephen, AG; Thibaut, L1

Other Studies

7 other study(ies) available for diminazene and furamidine

ArticleYear
Diaryl amidine derivatives as oncornaviral DNA polymerase inhibitors.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:7

    Topics: Amidines; Animals; Antineoplastic Agents; Kinetics; Leukemia, Experimental; Mice; Moloney murine leukemia virus; Retroviridae; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Tilorone

1980
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11

    Topics: Adenosine; Animals; Antimalarials; Dose-Response Relationship, Drug; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma cruzi

2007
In vivo investigations of selected diamidine compounds against Trypanosoma evansi using a mouse model.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Animals; Disease Models, Animal; Female; Mice; Parasitic Sensitivity Tests; Pentamidine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis

2009
Theoretical models of pentamidine analogs activity based on their DNA minor groove complexes.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:5

    Topics: Binding Sites; DNA; Models, Chemical; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Nucleic Acid Denaturation; Pentamidine; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature

2010
An evaluation of Minor Groove Binders as anti-Trypanosoma brucei brucei therapeutics.
    European journal of medicinal chemistry, 2016, Jun-30, Volume: 116

    Topics: Computer Simulation; HEK293 Cells; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.
    Biochemistry, 1996, May-07, Volume: 35, Issue:18

    Topics: Amidines; Animals; Antifungal Agents; Base Sequence; Benzamidines; Binding Sites; Diminazene; DNA; Intercalating Agents; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pneumocystis; Rats; Spectrophotometry; Thermodynamics; Trypanocidal Agents

1996
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1.
    Nucleic acids research, 2007, Volume: 35, Issue:13

    Topics: Antineoplastic Agents; Benzamidines; Diminazene; DNA; DNA, Single-Stranded; Drug Evaluation, Preclinical; Electrochemistry; Humans; Kinetics; Luminescent Measurements; Pentamidine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Thymidine

2007