diminazene has been researched along with diminazene aceturate in 534 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 129 (24.16) | 18.7374 |
| 1990's | 144 (26.97) | 18.2507 |
| 2000's | 71 (13.30) | 29.6817 |
| 2010's | 147 (27.53) | 24.3611 |
| 2020's | 43 (8.05) | 2.80 |
| Authors | Studies |
|---|---|
| Changtam, C; de Koning, HP; Gould, MK; Ibrahim, H; Sajid, MS; Suksamrarn, A | 1 |
| Loewe, H; Nagley, P; Vaughan, PR | 1 |
| Moore, DJ | 1 |
| Jones, TW; Uche, UE | 1 |
| Abdel Karim, EI; Mohamed-Ahmed, MM; Rahman, AH | 1 |
| Ainanshe, OA; Holmes, PH; Jennings, FW | 1 |
| Löhr, KF; Maloo, SH; Mbura, RJ; Münstermann, S | 1 |
| Bruijn, JA; Fleuren, GJ; van Leer, EH; van Velthuysen, ML | 1 |
| Junqueira, RG; Mares-Guia, M; Silva, E | 1 |
| Davis, WC; Goff, WL; Hamilton, MJ; Wyatt, CR | 1 |
| Claxton, JR; Dwinger, RH; Leperre, P; Rawlings, P; Snow, WF | 1 |
| Holmes, PH; Jennings, FW; Osman, AS | 1 |
| Adams, JH; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
| Bauer, B; Clausen, PH; Kaboré, I; Sidibe, I | 1 |
| Kawanishi, S; Yamamoto, K | 1 |
| Arakawa, A; Chitambo, H; Ono, T | 1 |
| Arakawa, A; Chitambo, H | 4 |
| Ikeda, I; Kamiyama, T; Matsubara, J; Niinuma, S | 1 |
| Aliu, YO; Gray, MA; Mamman, M; Moloo, SK; Peregrine, AS; Silayo, RS | 1 |
| Munyua, WK; Njogu, AR; Olaho-Mukani, W | 1 |
| Biagini, R; Cordelli, E; Cortesi, R; Esposito, E; Feriotto, G; Gambari, R; Menegatti, E; Nastruzzi, C; Pastesini, C; Spano, M | 1 |
| Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M | 1 |
| Gannon, P; Gray, JS | 1 |
| Libby, PR; Porter, CW | 1 |
| Jennings, FW | 2 |
| Neidle, S | 2 |
| Lynen, L; Van Damme, W | 1 |
| Ndarathi, CM | 1 |
| Brown, DG; Garman, E; Neidle, S; Sanderson, MR | 1 |
| Kaminsky, R; Zweygarth, E | 2 |
| Abuabara, JY; Otte, MJ | 1 |
| Elrayah, IE; Kaminsky, R | 1 |
| Huang, D; Huang, YT; Liang, JX; Lun, ZR; Min, ZP; Yang, XF | 1 |
| Baltz, T; Giroud, C; Zhang, ZQ | 2 |
| Haaf, T; Hoehn, H; Kausch, K; Köhler, J; Poot, M | 1 |
| Hu, SH; James, TL; Shafer, RH; Weisz, K | 1 |
| Jenkins, TC; Neidle, S; Walton, AR | 1 |
| Alunda, JM; Balaña-Fouce, R; Escribano, MI | 1 |
| Akiba, M; Ishii, T; Saeki, H; Ueda, K; Yamamoto, S | 1 |
| Egwu, GO; Onyeyili, PA; Orjiude, BA; Zaria, LT | 1 |
| Brun, R; Rab, S | 1 |
| Onwualu, JE; Onyeyili, PA | 1 |
| Gettinby, G; McOdimba, FA; Moloo, SK; Murray, M; Paling, RW; Scott, JR | 1 |
| Alushula, H; Dolan, RB; Mutugi, M; Njogu, AR; Okech, G; Sayer, PD; Stevenson, P | 1 |
| Kaminsky, R; Webster, P; Zweygarth, E | 1 |
| Brown, T; Jenkins, TC; Lane, AN; Neidle, S | 1 |
| Ibitayo, AI; Knowles, G; Moloo, SK; Murphy, NB; Peregrine, AS; Scott, JR | 1 |
| Hopkins, J; Luckins, AG; Mwangi, DM | 1 |
| Gupta, S; Kishore, P; Shukla, OP; Srivastava, DK | 1 |
| Jordt, T; Lorenzini, E | 1 |
| Englund, PT; Shapiro, TA | 1 |
| Grummt, F; Wegner, M | 1 |
| Fox, KR; Jenkins, TC; Laughton, CA; Neidle, S | 1 |
| Cole, AD; Gardner, KH; Kmiec, EB; Sekiguchi, JA | 1 |
| Anika, SM; Onyeyili, PA | 3 |
| Yoshimura, H | 1 |
| Chuma, F; Gumm, ID; Kaminsky, R; Zweygarth, E | 1 |
| Brown, DG; Brown, T; Garman, E; Jenkins, TC; Neidle, S; Sanderson, MR; Skelly, JV; Stuart, DI | 1 |
| Ross, CA; Taylor, AM | 1 |
| Banville, DL; Shafer, RH; Yoshida, M | 1 |
| Wähnert, U; Zimmer, C | 1 |
| Gago, F; Reynolds, CA; Richards, WG | 1 |
| Feichtinger, W; Guttenbach, M; Haaf, T; Müller, CR; Sanchez, L; Schmid, M | 1 |
| Alunda, JM; Balaña-Fouce, R; Ordóñez, D | 1 |
| Brun, R; Kunz, C | 1 |
| Chumo, DA; Kamar, KK; Muriithi, RM; Njogu, AR; Onyango, F; Reardon, MJ; Roberts, LM; Wellde, BT | 1 |
| Chumo, DA; Higgs, J; Kovatch, RM; Preston, JM; Wellde, BT | 1 |
| Akanji, MA; Ngaha, EO | 1 |
| Ibe, CC; Wosu, LO | 1 |
| Connor, RJ; Halliwell, RW; Mukangi, DJ | 1 |
| Kmiec, EB; Sekiguchi, JA | 1 |
| Rogers, DJ | 1 |
| Jefferies, D; Jenni, L | 2 |
| Brown, HC; Holmes, PH; Jennings, FW; Waitumbi, JN | 1 |
| Lekaki, KA; Mbwambo, HA; Mella, PN | 1 |
| Bauer, WR; Fairfield, FR; Simpson, MV | 1 |
| Portugal, J; Waring, MJ | 2 |
| Shaffer, R; Traktman, P | 1 |
| Neidle, S; Pearl, LH; Skelly, JV | 1 |
| Balaña-Fouce, R; Garrido-Pertierra, A; Garzón Pulido, T; Ordóñez-Escudero, D | 1 |
| Alushula, H; Gatuta, GM; Mgutu, SP; Njogu, AR; Wilson, AJ | 1 |
| Malu, MN; Tabel, H | 1 |
| Karvonen, E | 1 |
| Clarkson, AB; Rosenberg, C; Williams, DE | 1 |
| Molyneux, DH; Owolabi, OA | 1 |
| Kanno, Y; Namikawa, K; Sakuma, Y; Sunaga, F | 1 |
| Gardiner, PR; Murray, M; Whitelaw, DD | 1 |
| Dalvi, R | 1 |
| Kanno, Y; Namikawa, K; Sunaga, F | 1 |
| Gardiner, PR; Moloo, SK; Nelson, RT; Vos, GJ | 1 |
| Otesile, EB; Tabel, H | 1 |
| Rathaur, S; Walter, RD; Wittich, RM | 1 |
| Gardiner, PR; Moloo, SK; Vos, GJ | 1 |
| Kaggwa, E; Mugera, GM; Munyua, WK | 1 |
| Stewart, KD | 1 |
| Harvey, JW; Lewis, JC; Taboada, J | 1 |
| Balber, AE; Frommel, TO | 1 |
| Röttcher, D; Zweygarth, E | 1 |
| Moloo, SK; Röttcher, D; Schönefeld, A | 1 |
| Hofer, KG; Yasui, LS | 1 |
| Black, SJ; Hendershot, L; Mahan, SM | 1 |
| Dieleman, EF | 1 |
| Hudson, BD; Neidle, S; Pearl, LH; Skelly, JV | 1 |
| Jenni, L; Moloo, SK; Paling, RW | 1 |
| Gupta, S; Shukla, OP; Walter, RD | 1 |
| Abebe, G | 1 |
| Feichtinger, W; Haaf, T; Schmid, M | 1 |
| Bocoum, Z; Diall, O; Sanogo, Y; Yattara, Z | 1 |
| Bafort, JM; Molyneux, DH; Schmidt, H | 1 |
| Büttner, M; Reiter, I; Seitz, A | 1 |
| Dwinger, RH; Luckins, AG; Moloo, SK; Murray, M; Rae, P | 1 |
| Dehoux, JP; Demey, F; Makumyaviri, AM; Verhulst, A | 1 |
| Black, SJ; Koch, GL; Sendashonga, CN; Shapiro, SZ; Webster, P | 1 |
| Bitonti, AJ; Dumont, JA; McCann, PP | 1 |
| Akpavie, SO; Egbunike, GN; Ikede, BO | 1 |
| Akol, GW; Murray, M | 1 |
| Borowy, NK; Hirumi, H; Mkoji, G; Waithaka, HK | 1 |
| Karvonen, E; Kauppinen, L; Partanen, T; Pösö, H | 1 |
| Moulton, JE | 1 |
| Mitchell, LA; Pearson, TW | 1 |
| Urquhart, GM; Whitelaw, DD | 1 |
| Alvi, NK; Hadi, SM; Haqqi, TM | 1 |
| Borowy, NK; Fink, E; Hirumi, H | 1 |
| Oliver, M; Viens, P | 1 |
| Bovell, D; Brighouse, G; Poltera, AA; Rudin, W; Sayer, PD | 1 |
| Mitema, ES | 1 |
| Eckert, HG; Kellner, HM; Volz, MH | 1 |
| Lavery, R; Pullman, B; Zakrzewska, K | 1 |
| Gray, GD; Hajduk, SL; Jennings, FW | 1 |
| Gray, GD; Jennings, FW; Whitelaw, DD | 1 |
| Mansfield, JM; Sizemore, RC | 1 |
| Brun, G; Callen, JC; Scovassi, I; Vannier, P | 1 |
| Brougham, MJ; Holloman, WK; Ross, CF; Ross, WE | 1 |
| Donnini, C; Marmiroli, N; Puglisi, PP | 1 |
| Aicher, BM; Boch, J; Weiland, G | 1 |
| Bansal, GC; Sharma, SP | 1 |
| Abaru, DE; Isakina, D; Liwo, DA; Okori, EE | 1 |
| Ahmed, JS; Rehbein, G; Zweygarth, E | 1 |
| Aliu, YO; Odegaard, S; Søgnen, E | 1 |
| Farrell, NP; McLaren, DJ; Williamson, J | 1 |
| Chumo, DA; Wellde, BT | 1 |
| Küpper, W; Wolters, M | 1 |
| Jennings, FW; Urquhart, GM | 1 |
| Gilbert, RJ | 1 |
| Gray, JS | 1 |
| Gresh, N; Pullman, B | 1 |
| Craig, TM; Goodwin, JT; Logan, LL; Tembely, S | 1 |
| Emerole, GO; Thabrew, MI | 1 |
| Gray, GD; Jennings, FW | 2 |
| Beckers, A; Gigase, P; Mulumba, P; Van Marck, EA; Wéry, M | 1 |
| Cobb, CC; Farwell, GE; LeGrand, EK | 1 |
| Losos, GJ; McMillan, I; Minder, CE; Soulsby, K | 1 |
| Akpavie, SO; Ikede, BO | 1 |
| Moloo, SK; Morrison, WI; Murray, M; Paris, J; Wells, PW | 1 |
| Hellebrekers, LJ; Slappendel, RJ | 1 |
| Gilbert, RJ; Newton, BA | 1 |
| Joshua, RA | 1 |
| Adam, SE; Elamin, EA; Homeida, AM; Mahmoud, MM | 1 |
| Kuttler, KL | 1 |
| Uilenberg, G; Verdiesen, PA; Zwart, D | 1 |
| Dennig, HK; Göbel, E | 1 |
| Jennings, FW; Miller, BM; Murray, PK; Urquhart, GM | 1 |
| Losos, G; Rurangirwa, FR; Tabel, H; Tizard, IR | 1 |
| Akins, RA; Byers, TJ | 1 |
| Benard, J; Riou, G | 1 |
| Boo, KS; Forsberg, CM; Mills, JN; Valli, VE | 1 |
| Du Preez, JL; Gummow, B; Swan, GE | 1 |
| Breslauer, KJ; Pilch, DS | 1 |
| Bodley, AL; McGarry, MW; Shapiro, TA | 1 |
| Abu-Daya, A; Brown, PM; Fox, KR | 1 |
| Cagnolati, V; Mdachi, RE; Murilla, GA; Omukuba, JN | 1 |
| Breslauer, KJ; Kirolos, MA; Liu, X; Pilch, DS; Plum, GE | 1 |
| Antia, RE; Egbe-Nwiyi, TN | 2 |
| Jenkins, TC; McConnaughie, AW | 1 |
| d'Ieteren, GD; Mulatu, W; Nagda, SM; Rowlands, GJ | 1 |
| Chen, AY; Gatto, B; Liu, LF; Yu, C | 1 |
| Conte, MR; Jenkins, TC; Lane, AN | 1 |
| Madhubala, R; Mukhopadhyay, R | 1 |
| Mamman, M; Murphy, NB; Peregrine, AS; Williams, DJ | 1 |
| Mabbott, NA; Sternberg, JM; Sutherland, IA | 1 |
| Mamman, M; Peregrine, AS | 1 |
| Gray, MA; Kimarua, RW; Peregrine, AS; Stevenson, P | 1 |
| Agbe, SA; Yielding, KL | 1 |
| Kihurani, DO; Mbithi, PM; Mbiuki, SM; Mogoa, E; Nantulya, VM; Nguhiu-Mwangi, J | 1 |
| Durand, M; Maurizot, JC; Thuong, NT | 1 |
| Alunda, JM; Balaña-Fouce, R; Carrera, L | 1 |
| Chuma, F; Kaminsky, R; Wasike, RP | 1 |
| Koo, HS; Park, SM | 1 |
| Chuma, F; Kaminsky, R; Mamman, M; Zweygarth, E | 1 |
| Portugal, J | 1 |
| Mamman, M; Moloo, SK; Peregrine, AS | 1 |
| Bacchi, CJ; Clarkson, AB; Goldberg, B; McCann, PP; Nathan, HC; Saric, M; Sjoerdsma, A; Yarlett, N | 1 |
| Alvarez Bujidos, ML; Balaña Fouce, R; Cubria, JC; Ordoñez, D; Reguera, R | 1 |
| Colombatto, S; Cravanzola, C; Grillo, MA | 1 |
| Barceló, F; Portugal, J | 1 |
| Hübner, W; Schmitz, HU | 1 |
| Katende, J; Mamman, M; Moloo, SK; Peregrine, AS | 1 |
| Kano, M; Nagamune, K; Ohnishi, Y; Ono, T | 1 |
| Colombatto, S; Grillo, MA | 1 |
| Peña, MP; Roig, A; Stockert, JC; Vicente, F | 1 |
| Alvarez-Bujidos, ML; Balaña Fouce, R; Cubría, JC; Negro, A; Ordóñez, D; Ortiz, AI | 1 |
| Hagiwara, K; Ishihara, C; Iwai, H; Kurosawa, T; Tajima, M; Takahashi, K; Tsuji, M | 1 |
| Brown, DG; Jenkins, TC; Lane, AN; Neidle, S | 1 |
| Breslauer, KJ; Kirolos, MA; Pilch, DS | 1 |
| Anika, SM; Asuzu, IU; Odika, IE | 2 |
| Logan-Henfrey, L; McOdimba, F; Mwangi, SM | 1 |
| Agbe, A; Yielding, KL | 1 |
| James, R; Kim, HG; Mayfield, CA; Miller, DM; Rodu, B; Vigneswaran, N | 1 |
| Baltz, T; Barrett, MP; Denise, H; Giroud, C; Zhang, ZQ | 1 |
| Bailly, C; Colson, P; Houssier, C | 1 |
| de La Rocque, S; Desquesnes, M; Peregrine, AS | 1 |
| Bailly, C; Colson, P; Hamy, F; Houssier, C | 1 |
| Anene, BM; Anika, SM; Chukwu, CC; Ross, CA | 1 |
| Boykin, DW; Laughton, CA; Neidle, S; Nunn, CM; Tanious, F; Wilson, WD | 1 |
| Bwangamoi, O; Joshua, RA; Mandebvu, E; Obwolo, MJ | 1 |
| Alonso, C; Amo-Ochoa, P; Fuertes, MA; González, VM; Masaguer, JR; Navarro-Ranninger, C; Pérez, JM | 1 |
| Majumder, HK; Siddiqui, KA; Singh, R; Valenzuela, MS | 1 |
| Authié, E; Coulibaly, L; d'Ieteren, GD; Hecker, PA; Leak, SG; Rowlands, GJ | 1 |
| Brown, PM; Fox, KR | 1 |
| Blagburn, BL; Boykin, DW; Clark, GR; Hall, JE; Kumar, A; Neidle, S; Tidwell, RR; Trent, JO; Wilson, WD | 1 |
| Brazil-Zison, M; Dickerson, RE; Filipowsky, ME; Kopka, ML; Lown, JW | 1 |
| Atouguia, JM; Fernandes, JH; Jennings, FW; Peleteiro, MC; Rosário, VE | 1 |
| Diack, A; Moloo, SK; Peregrine, AS | 1 |
| Holmes, PH; Katunguka-Rwakishaya, E; Murray, M | 1 |
| Burke, JM; Gichuki, CW; Hunter, CA; Jennings, FW; Kennedy, PG; Murray, M; Rodgers, J | 1 |
| Scott, AG; Tait, A; Turner, CM | 1 |
| Armitage, B; Schuster, GB | 1 |
| Kulpa, V; Tua, A; Wang, J; Wernette, CM | 1 |
| Alonso, C; González, VM; Pérez, JM | 1 |
| Aguilar, R; Moraes, AS; Seidl, A; Silva, MS | 1 |
| Bai, Y; Guo, Y; Liu, Z; Yang, X | 1 |
| He, G; Shen, J; Wang, Q; Zhou, J | 1 |
| Milner, RJ; Reyers, F; Taylor, JH; van den Berg, JS | 1 |
| Enyaru, JC; Kaminsky, R; Lubega, GW; Matovu, E | 1 |
| Gordon, JR; Kaushik, RS; Tabel, H; Uzonna, JE | 2 |
| Da'dara, AA; Mett, H; Walter, RD | 1 |
| el-Metenawy, TM | 1 |
| Dolan, RB; Munga, L; Ndung'u, EK; Rossiter, PB; Stevenson, P | 1 |
| Amsler-Delafosse, S; Bauer, B; Kaboré, I; Kamuanga, M | 1 |
| Geerts, S; Goossens, B; Ndao, M; Osaer, S; Van Winghem, J | 1 |
| Dávila, AM; Ortiz, AG; Pereira, SR; Ramirez, L; Silva, RA; Souza, SS | 1 |
| Cullens, F; Greene, CE; Hopper, E; Latimer, K; Lower, K; Shoeffler, G | 1 |
| Büscher, P; Faye, JA; Mattioli, RC | 1 |
| Reinert, KE | 1 |
| Connor, RJ; Doran, M; Van den Bossche, P | 1 |
| de Paz, E; Merino, G; Negro, A; Rabanal, B | 1 |
| Davis, SS; Ehtezazi, T; Garnett, MC; Govender, T; Illum, L; Riley, T; Stolnik, S | 1 |
| Cho, A; Eliseev, AV; Ochoa Lara, KL; Yatsimirsky, AK | 1 |
| Bailly, C; Møllegaard, NE; Nielsen, PE; Waring, MJ | 1 |
| Abebe, G; Afewerk, Y; Clausen, PH; Mehlitz, D; Tilahun, G | 1 |
| Mwendia, C; Okech, G; Roderick, S; Stevenson, P | 1 |
| Dash, PK; Dwivedi, SK; Pathak, NN; Patra, RC; Sahoo, A | 1 |
| Bengaly, Z; Desquesnes, M; Kasbari, M; Sidibé, I | 1 |
| Bradley, B; Eckersall, PD; Gow, JW; Kennedy, PG; McComb, C; Murray, M; Rodgers, J | 1 |
| Ano, H; Makimura, S; Wijaya, A; Wulansari, R | 1 |
| Barceló, F; Ortiz-Lombardía, M; Portugal, J | 1 |
| Ariyibi, AA; Odunuga, OO; Olorunsogo, OO | 1 |
| Abebe, G; Assefa, E | 1 |
| Martin, RJ; Ross, CA; Suswam, EA; Taylor, DW | 1 |
| Allen, S; Gaub, HE; Krautbauer, R; Pope, LH; Schrader, TE | 1 |
| Asiri, SA; Ogbunude, PO | 1 |
| Durand, M; Maurizot, JC; Seche, E | 1 |
| Chen, Y; Coates, L; Ikpeazu, EV; Valenzuela, MS | 1 |
| De Pauw, E; Gabelica, V; Houssier, C; Rosu, F | 1 |
| Clausen, PH; Eisler, MC; McDermott, JJ; Mehlitz, D; Mitema, ES; Olila, D; Patzelt, RJ; Peregrine, AS; Poetzsch, CJ; Zessin, KH | 1 |
| Atsriku, C; Grant, MH; Skellern, GG; Tettey, JN; Watson, DG | 1 |
| Gessner, A; Kayser, O; Müller, RH; Olbrich, C | 1 |
| Edwards, TE; Sigurdsson, ST | 1 |
| Borisutsuwan, S; Jarabrum, W; Kongkanjana, N; Mohkaew, K; Theeraphan, A; Tuntasuvan, D; Viseshakul, N | 1 |
| Pan, YM; Snowden, TE; Valenzuela, MS | 1 |
| BAUER, F | 3 |
| ENIGK, K; REUSSE, U | 1 |
| AWAD, FI; HAIBA, MH; MAHMOUD, AH; ZAFER, SA | 1 |
| DI LUZIO, NR; SIMON, KA; UPTON, AC | 1 |
| HAWKING, F | 2 |
| POSCHEL, PH | 1 |
| KAYALI, HA | 1 |
| WHITESIDE, EF | 1 |
| KILLICK-KENDRICK, R | 1 |
| HARDY, GJ; HERBERT, WJ; LUMSDEN, WH | 1 |
| SCHUBERT, R | 1 |
| HUTCHINSON, MP; WATSON, HJ | 1 |
| Feichtinger, W; Felbor, U; Schmid, M | 1 |
| Atsriku, C; Grant, MH; Skellern, GG; Watson, DG | 1 |
| Tanyildizi, S; Türk, G | 1 |
| Martin, RJ; Ross, CA; Suswam, EA | 1 |
| Rudenko, G; Sheader, K; te Vruchte, D | 1 |
| Jooste, R; Lumamba, D; Mubanga, J; Munsimbwe, L; Van den Bossche, P | 1 |
| Joubert, KE; Kettner, F; Lobetti, RG; Miller, DM | 1 |
| Anderson, LF; Barrett, MP; Burchmore, RJ; de Koning, HP; Stewart, M; Wallace, LJ | 1 |
| Abebe, G; Afework, Y; Clausen, PH; Eisler, M; Greiner, M; Kyule, M; McDermott, J; Münstermann, S; Tewelde, N; Zessin, KH | 1 |
| Fauth, E; Rosefort, C; Zankl, H | 1 |
| Bauer, B; Clausen, PH; Gall, Y; McDermott, J; Mehlitz, D; Sidibe, I; Woitag, T | 1 |
| Campbell, M; Charman, WN; Davie, AS; Prankerd, RJ | 1 |
| Magona, JW; Mayende, JS; Okiria, R; Okuna, NM | 1 |
| Coffinier, Y; Durand, JO; Grandidier, B; Melnyk, O; Olivier, C; Perzyna, A; Stiévenard, D; Wallart, X | 1 |
| d'Ieteren, GD; McDermott, JJ; Mulatu, W; Nagda, SM; Rowlands, GJ; Schukken, YH; van Schaik, G | 1 |
| Magona, JW; Olaho-Mukani, W; Walubengo, J | 1 |
| Govender, T; Prompruk, K; Stolnik, S; Xiong, CD; Zhang, S | 1 |
| Inoue, N; Ohashi, K; Onuma, M; Tsuda, A; Witola, WH | 1 |
| Lopes, JC; Martins-José, A; Pereira, MT; Santoro, MM; Silva-Alves, JM | 1 |
| Egbe-Nwiyi, TN; Igbokwe, IO; Onyeyili, PA | 1 |
| Coombs, GH; Goyeneche, D; Jean-Moreno, V; Rojas, R; Walker, J | 1 |
| Kuroda, R; Nitta, Y | 1 |
| Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN | 1 |
| Baleanu, D; Dinç, E; Kanbur, M | 1 |
| Kaboya, JS; Kibona, SN; Lubega, GW; Matemba, L | 1 |
| Akinwale, OP; Edeghere, HU; Esievo, KA; Nock, IH; Olukosi, YA | 1 |
| Jamal, S; Macuamule, C; Marcotty, T; Neves, L; Penzhorn, BL; Sigauque, I; Van Den Bossche, P | 1 |
| Andersen, WC; Clark, SB; Hurlbut, JA; Karbiwnyk, CM; Miller, KE; Turnipseed, SB | 1 |
| Batista, JS; Madruga, CR; Maia, TF; Riet-Correa, F; Simões, SD; Teixeira, MM | 1 |
| Chitanga, S; Delespaux, V; Geerts, S; Geysen, D; Goethals, A; van den Bossche, P | 1 |
| Agama, KK; Antony, S; Fisher, RJ; Marchand, C; Pommier, Y; Stephen, AG; Thibaut, L | 1 |
| Kagira, JM; Maina, N | 1 |
| Katakura, K; Maede, Y; Matsuura, H; Nabeta, K; Takahashi, K; Yamasaki, M | 1 |
| Burke, J; Eckersall, PD; Jennings, FW; Mburu, J; Mungatana, N; Murray, M; Ngure, RM | 1 |
| Akpa, PO; Anene, BM; Eze, CA; Ezeokonkwo, RC | 1 |
| Asnake, F; Basu, AK; Hagos, A; Miruk, A; Yacob, HT | 1 |
| Brown, AD; Eckdahl, TT; Hart, SN; Heyer, LJ; Hoopes, LL; Malloy, KJ; Shott, M; Yiu, G | 1 |
| Soliman, GM; Winnik, FM | 1 |
| Chaudhry, M; Khan, MA; Mahmood, AK; Pervez, K; Rashid, H; Rashid, HB | 1 |
| Delespaux, V; Dinka, H; Geerts, S; Masumu, J; Van den Bossche, P | 1 |
| Aliyu, MM; Ibrahim, UI; Mbaya, AW; Nwosu, CO; Taiwo, VO | 1 |
| Farah, IO; Hau, J; Jensen, HE; Kagira, JM; Karanja, SM; Ngotho, M | 1 |
| Brown, DE; Collyer, CA; Dooley, DM; Elmore, BO; Guss, JM; Hilmer, KM; McGrath, AP; Shepard, EM | 1 |
| Nguyen, B; Wilson, WD | 1 |
| Barrett, MP; Brooks, K; Burchmore, RJ; Clucas, C; De Koning, HP; Hertz-Fowler, C; Macleod, A; Stewart, ML; Tait, A; Turner, CM; Wong, PE | 1 |
| Hwang, SJ; Maede, Y; Murakami, M; Nakamura, K; Ohta, H; Sasaki, N; Takiguchi, M; Wickramasekara Rajapakshage, BK; Yamasaki, M | 1 |
| Nagem, RA; Pereira, MT; Perilo, CS; Santoro, MM | 1 |
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| Alemu, T; Claes, F; Feseha, G; Fikru, R; Goddeeris, BM; Hagos, A; Yacob, HT; Yilkal, K | 1 |
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| Adame, A; Clark, LN; Cote, L; Geddie, ML; Ju, S; Lewandowski, NM; Lindquist, S; Marder, K; Masliah, E; Muhammad, A; Petsko, GA; Ringe, D; Rockenstein, E; Ross, B; Small, SA; Verbitsky, M; Vonsattel, JP | 1 |
| Hwang, SJ; Kumara, B; Maede, Y; Murakami, M; Nakamura, K; Ohta, H; Rajapakshage, W; Sasaki, N; Takiguchi, M; Yamasaki, M | 1 |
| Almeida, P; Caramelo-Nunes, C; Marcos, JC; Tente, T; Tomaz, CT | 1 |
| Farah, IO; Hau, J; Kagira, JM; Kariuki, C; Maina, N; Mwangangi, DM; Ngotho, M; Thuita, JK | 1 |
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| Costa, MM; Da Silva, AS; Dornelles, GL; França, RT; Labruna, MB; Lopes, ST; Mazzanti, CM; Monteiro, SG; Paim, CB; Paim, FC; Soares, JF | 1 |
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| Christopher, MM; Leisewitz, AL; Scheepers, E; Thompson, PN | 1 |
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| Anene, BM; Asuzu, IU; Nweze, NE | 1 |
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| Bengaly, Z; Delespaux, V; Marcotty, T; Sidibe, I; Van Den Abbeele, J; Vitouley, HS | 1 |
| Almeida, P; Caramelo-Nunes, C; Gabriel, MF; Marcos, JC; Tomaz, CT | 2 |
| Aboulaila, M; El-Sify, A; Hassan, HY; Igarashi, I; Moussa, AA; Nayel, MA; Salama, AA; Terkawi, MA; Yokoyama, N | 1 |
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| Lim, SY; Murakami, M; Nakamura, K; Ohta, H; Osuga, T; Rajapakshage, BK; Sasaki, N; Takiguchi, M; Tamura, Y; Yamasaki, M | 1 |
| Abenga, JN; Enwezor, FN; Ijabor, O; Samdi, SM | 1 |
| Jia, P; Kuriakose, S; Muleme, HM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
| Carr, G; Combrink, MP; Mans, BJ; Marais, F | 1 |
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| Costa, MM; Da Silva, AS; França, RT; Labruna, MB; Lopes, ST; Mazzanti, CM; Paim, FC; Soares, JF | 1 |
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| Ezeh, IO; Ezeokonkwo, RC; Idika, IK; Iheagwam, CN; Obi, CF; Obidike, RI; Omoja, VU | 1 |
| Casali, KR; Katovich, MJ; Raizada, MK; Rigatto, K; Shenoy, V | 1 |
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| Lourenção, AL; Mendonça, EG; Oliveira, JA; Oliveira, MG; Paixão, GP; Silva, CR; Silva, PL; Zanuncio, JC | 1 |
| Guedes, RN; Lourenção, AL; Marinho-Prado, JS; Oliveira, JA; Oliveira, MG; Pallini, A | 1 |
| Cole-Jeffrey, CT; Espejo, A; Hanna, M; Katovich, MJ; Pepine, CJ; Qi, Y; Raizada, MK; Shenoy, V; Song, C; Zhang, J | 1 |
| Birkenheuer, AJ; Cohn, LA; Lewis, KM; Marr, HS | 1 |
| AbouLaila, M; Allaam, M; El-Sify, A; Igarashi, I; Mousa, A; Salama, AA; Terkawi, MA; Yokoyama, N; Zaghawa, A | 1 |
| Kuriakose, S; Muleme, H; Okeke, E; Onyilagha, C; Uzonna, JE | 1 |
| Dey, S; Kumar, R; Ranjithkumar, M; Saravanan, BC; Singh, R; Yadav, SC | 1 |
| Aluwong, T; Ambali, SF; Ayo, JO; Kobo, PI; Maikai, V; Zezi, AU | 1 |
| Almeida, P; Caramelo-Nunes, C; Marcos, JC; Tomaz, CT | 1 |
| Isaac, AO; Nyariki, JN; Rashid, K; Wachira, FN | 1 |
| Beck, RC; DA Silva, AS; Gressler, LT; Miletti, LC; Monteiro, SG; Oliveira, CB; Ourique, AF; Rigo, LA; Rosa, LD; Zimmermann, CE | 1 |
| Gay, RE; Gay, S; Jüngel, A; Karouzakis, E; Neidhart, M | 1 |
| Asres, K; Bisrat, D; Terefe, G; Tewabe, Y | 1 |
| Luiz, AJ; Maia, Ade H; Marinho-Prado, JS; Pazianotto, RA; Pervez, A | 1 |
| Feyera, T; Shibeshi, W; Terefe, G | 1 |
| Coutinho, DC; Ferreira, AJ; Medei, E; Monnerat-Cahli, G | 1 |
| Lei, B; Li, Q; Qiu, Y; Shil, PK; Verma, A; Yang, H; Zhu, P | 1 |
| Kuriakose, S; Uzonna, JE | 1 |
| ElSaid, Eel S; Elsayed, SA; Guswanto, A; Igarashi, I; Rizk, MA; Sivakumar, T; Yokoyama, N; Youssef, MA | 1 |
| Chekwube, AI; Ezeokonkwo, RC; Ikenna, UE; Onyema, EI | 1 |
| Kalia, D; Le, V; Lewis, EA; Mikek, C; Nakayama, S; Sintim, HO; Zhou, J | 1 |
| Hatendorf, J; Kabasa, JD; Muhanguzi, D; Picozzi, K; Thrusfield, M; Waiswa, C; Welburn, SC | 2 |
| Beck, RC; Da Silva, AS; Dalla Rosa, L; Doyle, RL; França, RT; Gressler, LT; Lopes, ST; Monteiro, SG; Moreira, KL; Oliveira, CB; Oliveira, DT; Ourique, AF; Rigo, LA; Veiga, ML | 1 |
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| Mohammed, A; Ndidi, US; Oladeru, AO; Samuel, C; Umar, IA; Yakubu, RN | 1 |
| Alves, MP; Athayde, ML; Baldissera, MD; Boligon, AA; Da Silva, AS; Do Carmo, GM; França, RT; Lopes, ST; Mendes, RE; Monteiro, SG; Oliveira, CB; Rech, VC; Sagrillo, MR; Schwertz, CI; Vaucher, RA | 1 |
| Amadio, S; Bergamaschi, A; Bianchi, V; Biffi, E; Chaabane, L; Comi, G; D'Adamo, P; de Ceglia, R; Del Carro, U; Ferrigno, G; Forti, L; Martino, G; Mazzocchi, N; Menegon, A; Muzio, L; Taverna, S | 1 |
| Andrade, JM; Batista de Paula, AM; de Macedo, SM; Ferreira, AJ; Guimaraes, AL; Guimarares, TA; Sousa Santos, SH | 1 |
| De Deken, R; Delespaux, V; Duchateau, L; Moti, Y; Thys, E; Van Den Abbeele, J | 1 |
| Burrell, LM; Griggs, K; Patel, SK; Pickering, RJ; Tikellis, C; Velkoska, E | 1 |
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| Chen, Z; Lei, B; Lei, C; Qiu, Y; Yang, H; Zheng, C; Zheng, S | 1 |
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| Cardoso, VN; Castilho, RO; Cronemberger, S; Faraco, AA; Fernandes, SO; Ferreira, AJ; Foureaux, G; Franca, JR; Fulgêncio, Gde O; Fuscaldi, LL; Nogueira, JC; Ribeiro, TG; Yoshida, MI | 1 |
| Zsila, F | 1 |
| Baker, MB; Castellano, RK; Guo, L; Jarajapu, YP; Joshi, S; Li, Y; Raizada, MK; Singh, N | 1 |
| Araújo, LD; De Maria, ML; Ferreira, AJ; Fraga-Silva, RA; Menezes, GB; Pereira, LA; Raizada, MK; Ribeiro, HJ; Shenoy, V | 1 |
| da Silva Oliveira, GL; de Freitas, RM | 1 |
| De Ceglia, R; Forti, L; Mazza, D; Mazzocchi, N; Menegon, A; Muzio, L | 1 |
| Baldissera, MD; da Silva, AS; Grando, TH; Gressler, LT; Monteiro, SG; Souza, CF; Stefani, LM | 1 |
| Červenka, L; Červenková, L; Doleželová, Š; Husková, Z; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Nishiyama, A; Sadowski, J; Škaroupková, P; Vaňourková, Z | 1 |
| Adomefa, K; Akoda, K; Assoumy, AM; Bankolé, AA; Batawui, K; Clausen, PH; De Deken, R; Delespaux, V; Hoppenheit, A; Kombiagou, K; Kulo, AE; Marcotty, T; Mattioli, RC; Napier, GB; Niang, EM; Peter, R; Tchamdja, E; Teko-Agbo, A; Van Den Abbeele, J | 1 |
| Chalermwong, P; Desquesnes, M; Herder, S; Jittapalapong, S; Kunphukhieo, P; Yangtara, S | 1 |
| Hao, C; He, Y; Huang, B; Kuang, N; Liu, S; Wang, L; Zhou, T | 1 |
| Birhanu, H; Büscher, P; Gebrehiwot, T; Goddeeris, BM; Van Reet, N | 1 |
| Baldissera, MD; Cossetin, LF; da Silva, AP; Da Silva, AS; Dalla Lana, DF; Grando, TH; Monteiro, SG; Nascimento, K; Sagrillo, MR; Souza, CF; Stefani, LM | 1 |
| Borges, CL; Castro, CH; Colugnati, DB; De Maria, ML; Ferreira, AJ; Macedo, LM; Mendes, EP; Pedrino, GR; Santos, RA; Soares, CM; Souza, ÁP | 1 |
| Araújo, TS; Cerqueira, GS; Costa, DS; Martins, CS; Medeiros, JV; Nicolau, LA; Pacífico, DM; Silva, RO; Sousa, FB; Sousa, NA; Souza, FM; Souza, LK; Souza, MH | 1 |
| Amara, VR; Dhawale, VS; Karpe, PA; Malek, V; Patel, D; Tikoo, K | 1 |
| Burrell, LM; Patel, SK; Velkoska, E | 1 |
| Castro, CH; Ferreira-Neto, ML; Freiria-Oliveira, AH; Lopes, PR; Macedo, LM; Marques, SM; Moreira, MC; Pedrino, GR; Pinto, IS; Rebelo, AC; Reis, AA; Rosa, DA; Silva, CC | 1 |
| Burrell, LM; Griggs, K; Patel, SK; Velkoska, E | 1 |
| Ademola, IO; Odeniran, PO | 1 |
| Gachie, BM; Kagira, JM; Karanja, SM; Maina, NW; Maranga, DN; Ngotho, M; Waema, MW | 1 |
| Adjahoutonon, B; Cossic, BGA; Dibanganga, GL; Gloaguen, P; Leroy, P; MacLeod, ET; Maganga, G; Picozzi, K | 1 |
| Cao, S; Efstratiou, A; Igarashi, I; Kamyingkird, K; Mousa, AA; Nishikawa, Y; Salama, A; Tuvshintulga, B; Xuan, X; Yokoyama, N | 1 |
| Adomefa, K; Bankolé, AA; Batawui, K; Cecchi, G; Clausen, PH; De Deken, R; Delespaux, V; Hoppenheit, A; Kulo, AE; Marcotty, T; Tchamdja, E; Van Den Abbeele, J; Vitouley, HS | 1 |
| Grimmelsmann, L; Hättig, C; Marefat Khah, A; Nuernberger, P; Spies, C | 1 |
| Inoue, N; Molefe, NI; Suganuma, K | 1 |
| AbouLaila, M; El-Sayed, SAE; Igarashi, I; Rizk, MA; Yokoyama, N | 1 |
| Akbar, H; Ashraf, K; Gharbi, M; Islam, S; Rashid, I; Riaz, F; Rouatbi, M; Saleem, MB; Shahzad, S; Shehzad, W | 1 |
| Camoin, M; Chalermwong, P; Desquesnes, M; Jittapalapong, S; Kocher, A; Thongtip, N; Yangtarra, S | 1 |
| Aboge, G; Bett, B; Kihara, A; Mutua, F; Ngwili, N; Rogena, J; Wabacha, J | 1 |
| AbouLaila, M; El-Sayed, SAE; Eltaysh, R; Igarashi, I; Rizk, MA; Yokoyama, N | 1 |
| Chen, H; Liu, R; Pan, L; Yu, J; Zeng, Z; Zhong, Q; Zhou, Y | 1 |
| AbouLaila, M; Gantuya, S; Guswanto, A; Igarashi, I; Ishiyama, A; Iwatsuki, M; Naranbaatar, K; Ōmura, S; Otoguro, K; Rizk, MA; Sivakumar, T; Tayebwa, DS; Terkawi, MA; Tuvshintulga, B; Yokoyama, N | 1 |
| Idaka, N; Iguchi, A; Ohta, H; Otsuguro, K; Takiguchi, M; Uchida, N; Watanabe, N; Yamamori, T; Yamasaki, M | 1 |
| Dai, J; Ge, P; Jiang, R; Li, J; Yao, X; Zhang, L | 1 |
| Akoda, KG; Ashenafi, H; Cecchi, G; Cherenet, T; Clausen, PH; Delespaux, V; Gari, G; Hoppenheit, A; Marcotty, T; Mattioli, RC; Peter, R; Tekle, T; Teko-Agbo, A; Terefe, G; Van Den Abbeele, J | 1 |
| Bruce, EB; Cahill, KM; de Kloet, AD; Hiller, H; Katovich, MJ; Krause, EG; Ludin, JA; Pioquinto, DJ; Raizada, MK; Smeltzer, MD; Wang, LA | 1 |
| Adeleye, AI; Adeleye, OE; Adeyemi, SO; Ale, JM; Durotoye, LA; Olukunle, JO; Sogebi, EOA | 1 |
| Braissant, O; Brun, R; Gillingwater, K; Gysin, M; Mäser, P; Wenzler, T | 1 |
| Li, SM; Liu, F; Wang, XY; Yang, XH | 1 |
| Angus, PW; Burrell, LM; Herath, CB; Huang, P; Mak, KY; Rajapaksha, IG | 1 |
| Bruce, EB; Carter, CS; Kirichenko, N; Morgan, D; Sakarya, Y; Scarpace, PJ; Sumners, C; Toklu, HZ; Tümer, N | 1 |
| Castardeli, C; Forechi, L; Mill, JG; Pimentel, EB; Sartório, CL | 1 |
| Birhanu, H; Büscher, P; Kidane, W; Mekonnen, G; Mohammed, EF; Nesibu, A; Van Reet, N; Yohannes, H | 1 |
| Chen, X; Hu, Y; Jiao, Z; Kan, Y; Leng, C; Peng, Y; Shi, H; Yang, H; Yao, L | 1 |
| Adam, Y; Bayala, B; Belem, AMG; Bengaly, Z; Cecchi, G; Delespaux, V; Sidibé, I; Somda, MB; Têko-Agbo, A; Van Den Abbeele, J; Vitouley, SH; Zongo, A | 1 |
| Batawui, K; Bauer, B; Clausen, PH; Delespaux, V; Den Abbeele, JV; Hoppenheit, A; Kulo, AE; Tchamdja, E | 1 |
| Jia, P; Kuriakose, SM; Onyilagha, C; Singh, R; Uzonna, JE | 1 |
| Waiswa, C; Wangoola, MR | 1 |
| El-Sayed, SAE; Igarashi, I; Rizk, MA; Yokoyama, N | 1 |
| Kishore, A; Nandakumar, S; Raj, V; Thekkuveettil, A; Vijayan, B | 1 |
| Gaikwad, AB; Malek, V; Sankrityayan, H; Sharma, N | 1 |
| Igarashi, I; Sivakumar, T; Tuvshintulga, B; Yokoyama, N | 1 |
| Badae, NM; El Naggar, AS; El Sayed, SM | 1 |
| Jallow, S; Raftery, AG; Rodgers, J; Sutton, DGM | 1 |
| da Silva Filha, R; de Almeida, TCS; de Andrade De Maria, ML; Ferreira, AJ; Kangussu, LM; Prestes, TRR; Silva, ACSE; Vieira, MAR | 1 |
| Ademola, IO; Macleod, ET; Odeniran, PO; Welburn, SC | 1 |
| Adjimani, JP; Amisigo, CM; Antwi, CA; Gwira, TM | 1 |
| Ashenafi, H; Asres, K; Degneh, E; Kassa, T; Kebede, N; Shibeshi, W; Terefe, G | 1 |
| Borges, FA; Cleveland, HPK; Crepaldi, BA; Echeverria, JT; Martins, TB; Oliveira, GG; Pupin, RC; Ramos, CADN; Silva, PMPD; Soares, RL | 1 |
| Freza, S; Samsonov, SA; Zsila, F | 1 |
| Fang, Y; Gao, F; Liu, Z | 1 |
| Gaikwad, AB; Malek, V; Sharma, N | 1 |
| Bessa, ASM; Biancardi, MF; Castro, CH; Colugnati, DB; Costa, JM; Dos Santos, FCA; Jesus, ÉF; Lacerda, IS; Lino-Júnior, RS; Mazaro-Costa, R; Mendes, EP; Nunes, ADC; Pedrino, GR; Pontes, CNR; Souza, EJ | 1 |
| Cruz, JS; Ferreira, AJ; Joca, HC; Joviano-Santos, JV; Santos-Miranda, A | 1 |
| Caruso-Varès, A; Chevtzoff, C; Collin, JF; Isaka, N; Lumumba, PA; Maichomo, MW; Mungube, EO; Nginyi, JM; Njanja, JC; Pagny, G | 1 |
| Apostolopoulos, V; Egom, EE; Gadanec, LK; Kruzliak, P; Kubatka, P; Levinger, I; McSweeney, KR; Qaradakhi, T; Rimarova, K; Rodrigo, L; Tacey, A; Zulli, A | 1 |
| Evans, CE; Good, MA; Heard, DM; Kehoe, PG; Kidd, EJ; Miners, JS; Piva, G; Willis, CL | 1 |
| Fujita, M; Hung, WY; Nakagawa, K; Nakagawasai, O; Nemoto, W; Tadano, T; Tan-No, K; Yamagata, R | 1 |
| El-Saber Batiha, G; Igarashi, I; Magdy Beshbishy, A; Nadwa, E; Rashwan, E; Stephen Adeyemi, O; Yokoyama, N | 1 |
| Atanasova, KR; Bravo, L; Collins, EN; Dadural, JS; Eken, E; Guevara, MV; Kuan, SP; Liao, YSJ; Reznikov, LR; Schurmann, V; Sponchiado, M; Vogt, K | 1 |
| Battsetseg, B; Battur, B; Davaasuren, B; Davkharbayar, B; Inoue, N; Mizushima, D; Narantsatsral, S; Punsantsogvoo, M; Suganuma, K | 1 |
| Elgazzar, EM; Hasan, HF; Mostafa, DM | 1 |
| Farikou, O; Kamga, RMN; Magang, MEK; Mewamba, EM; Ravel, S; Simo, G; Tiofack, AAZ; Tume, C | 1 |
| Ezeh, IO; Ezeokonkwo, RC; Idika, IK; Mbe, N; Nwobi, LG; Obi, CF; Okpala, MI | 1 |
| Gaikwad, AB; Sharma, N | 2 |
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| Hättig, C; Kongsted, J; Marefat Khah, A; Nuernberger, P; Reinholdt, P | 1 |
| Dos Santos, RL; Mill, JG; Pimentel, EB; Rouver, WN; Sartório, CL | 1 |
| Apostolopoulos, V; Gadanec, L; Matsoukas, J; Qaradakhi, T; Zulli, A | 1 |
| Caldas, IS; Diniz, LF; Gonçalves, RV; Gonçalves-Santos, E; Mazzeti, AL; Novaes, RD; Souza-Silva, TG; Vilas-Boas, DF | 1 |
| Duan, R; E, Y; Gong, PY; Jiang, T; Wang, SY; Xue, X; Zhang, QQ; Zhang, YD | 1 |
| Correa, AMB; de Almeida, JFQ; Ferreira, AJ; Fontes, MAP; Kushmerick, C; Moreira, FA; Patel, KP; Sharma, NM; Silva, CC | 1 |
| Emeto, UE; Nweze, NE; Okolo, CC | 1 |
| Chai, CY; Chen, IC; Dai, ZK; Hsu, JH; Lin, JY; Liu, YC; Wu, BN; Yeh, JL | 1 |
| Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK | 1 |
| C Campos, LMC; Caliari, MV; Chagas, MW; da Silva Filha, R; de Sá, MA; Ferreira, AJ; Fonseca, EG; Kangussu, LM; Lanza, K; Rocha, NP; Silva de Almeida, TC; Simões E Silva, AC; Vieira, MAR | 1 |
| Abe, M; Idaka, N; Takiguchi, M; Yamasaki, M | 1 |
| Feng, XX; He, WH; Li, YY; Wu, X; Yao, DW; Zhai, XH; Zhang, B | 1 |
| Jia, F; Li, X; Ma, W; Zhang, X; Zhou, X | 1 |
| Białas, M; Bujak-Giżycka, B; Jawień, J; Kiepura, A; Kuś, K; Olszanecki, R; Stachowicz, A; Stachyra, K; Suski, M; Totoń-Żurańska, J; Wiśniewska, A; Łomnicka, M | 1 |
| Galon, EM; Igarashi, I; Ji, S; Li, J; Li, Y; Liu, M; Rizk, MA; Xuan, X; Zafar, I | 1 |
| Gaikwad, AB; Kale, A; Sankrityayan, H | 1 |
| Abdel-Daim, MM; Alkhoudary, MS; Alsharif, KF; El-Sayed, SAE; Igarashi, I; Rizk, MA | 1 |
| Balabadi, D; Essodina, T; Martin Bienvenu, S; Soudah, B; Toï, N; Wendemanegde Ernest, S; Yao, L | 1 |
| Coutinho, DCO; Cruz, JS; Ferreira, AJ; Foureaux, G; Joviano-Santos, JV; Martins-Júnior, PA; Medei, E; Resende, RR; Rodrigues-Ferreira, C; Santos, A; Santos, RAS; Santos-Miranda, A; Vieyra, A | 1 |
| Esfahani, SH; Karamyan, VT | 1 |
| Chen, J; Cheng, W; Gao, T; Jian, Z; Li, B; Li, C; Wang, G; Wang, L; Zhao, T | 1 |
| Gupta, S; Hanif, K; Mishra, A; Shukla, S; Tiwari, P; Tiwari, V | 1 |
| El-Sayed, SAE; Igarashi, I; Rizk, MA | 1 |
| Erin, JP; Kolawole, BJ; Nwoha, RIO; Orakpoghenor, O | 1 |
| Du, Y; Lu, Z; Wang, G; Wang, Z; Wu, D; Zhang, H | 1 |
| Fish, BL; Frei, AC; Gasperetti, T; Himburg, HA; Narayanan, J; Pierce, L; Sharma, GP; Szalewski, N; Veley, D | 1 |
| Aquino, CC; Araujo, AR; Barros, RO; Medeiros, JVR; Nicolau, LAD; Pacheco, G; Ramos, RM; Rocha, JA; Santos, ES; Silva, PC; Sousa, FBM; Sousa, PSA; Teixeira, LFLS | 1 |
| Ekloh, W; Gwira, TM; Sunter, JD | 1 |
| Alusi, PM; Auma, JE; Chemuliti, JK; Kurgat, RK; Mdachi, RE; Mugunieri, LG; Mukiria, PW; Ogolla, KO; Okoth, SO; Wamwiri, FN; Wanjala, KB | 1 |
13 review(s) available for diminazene and diminazene aceturate
| Article | Year |
|---|---|
Nonintercalating DNA-binding ligands: specificity of the interaction and their use as tools in biophysical, biochemical and biological investigations of the genetic material.
Topics: Aminoglycosides; Animals; Anthramycin; Antibiotics, Antineoplastic; Base Sequence; Binding Sites; Bisbenzimidazole; Cattle; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromosomes; Circular Dichroism; Diminazene; Distamycins; DNA; DNA, Superhelical; Drug Interactions; Duocarmycins; Indoles; Leucomycins; Ligands; Magnetic Resonance Spectroscopy; Mathematics; Models, Molecular; Netropsin; Plicamycin; Protein Conformation; Pyridinium Compounds; RNA; Spectrophotometry, Ultraviolet; Staining and Labeling; Thermodynamics | 1986 |
Trypanosomiasis 'risk' or 'challenge': a review.
Topics: Africa, Eastern; Africa, Western; Animals; Cattle; Diminazene; Humans; Risk; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
DNA structure and perturbation by drug binding.
Topics: Base Sequence; Diminazene; DNA; Echinomycin; Intercalating Agents; Macromolecular Substances; Models, Molecular; Netropsin; Nogalamycin; Pharmaceutical Preparations | 1987 |
Trypanosomiasis in Indonesia. A review of research, 1900-1983.
Topics: Animals; Arthropod Vectors; Diminazene; Phenanthridines; Suramin; Trypanosomiasis | 1986 |
Pharmacology of diminazene: a review.
Topics: Animals; Animals, Domestic; Diminazene; Drug Resistance; Drug Therapy, Combination; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1993 |
DNA minor-groove recognition by small molecules.
Topics: Base Sequence; Benzimidazoles; Bisbenzimidazole; Crystallography, X-Ray; Diminazene; Distamycins; DNA; DNA Probes; DNA-Binding Proteins; Indoles; Ligands; Molecular Conformation; Molecular Structure; Netropsin; Nylons; Oligodeoxyribonucleotides; Sequence Analysis, DNA | 2001 |
The rare human fragile site 16B.
Topics: Chromosome Aberrations; Chromosome Banding; Chromosome Fragile Sites; Chromosomes, Human, Pair 16; Diminazene; Distamycins; Humans; Karyotyping | 2003 |
Aromatic ligands for plasmid deoxyribonucleic acid chromatographic analysis and purification: an overview.
Topics: Amino Acids; Benzene Derivatives; Boronic Acids; Chromatography; Diminazene; DNA; Imidazoles; Ligands; Phenanthridines; Plasmids; Quinine; Sulfhydryl Compounds; Sulfides | 2014 |
Diminazene aceturate (Berenil), a new use for an old compound?
Topics: Animals; Cytokines; Diminazene; Humans; Inflammation; Signal Transduction; Transcription Factors | 2014 |
Diminazene aceturate--An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics.
Topics: Animals; Antiparasitic Agents; Diminazene; Humans; Trypanosomiasis | 2015 |
Angiotensin converting enzyme 2 and diminazene: role in cardiovascular and blood pressure regulation.
Topics: Angiotensin-Converting Enzyme 2; Blood Pressure; Cardiovascular System; Diminazene; Enzyme Activation; Humans; Hypertension; Peptidyl-Dipeptidase A; Trypanocidal Agents | 2016 |
The potential actions of angiotensin-converting enzyme II (ACE2) activator diminazene aceturate (DIZE) in various diseases.
Topics: Angiotensin-Converting Enzyme 2; Animals; Cardiovascular Diseases; Diminazene; Enzyme Activation; Enzyme Activators; Humans; Neoplasms; Renin-Angiotensin System | 2020 |
Diminazene Aceturate, an angiotensin converting enzyme 2 (ACE2) activator, promotes cardioprotection in ischemia/reperfusion-induced cardiac injury.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme 2; Animals; Arrhythmias, Cardiac; Diminazene; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Reperfusion; Reperfusion Injury | 2022 |
15 trial(s) available for diminazene and diminazene aceturate
| Article | Year |
|---|---|
Local application of diminazene aceturate: an effective treatment for cutaneous leishmaniasis?
Topics: Antiprotozoal Agents; Cetrimonium Compounds; Child; Chlorhexidine; Diminazene; Female; Humans; Leishmaniasis, Cutaneous; Male | 1992 |
Apparent rarity of diminazene-resistant trypanosomes in goats infected with a diminazene-resistant population of Trypanosoma congolense.
Topics: Animals; Antibodies, Protozoan; Diminazene; Drug Resistance; Flow Cytometry; Goat Diseases; Goats; Male; Phenotype; Trypanosoma congolense; Trypanosomiasis, African | 1995 |
Variation in sensitivity of Trypanosoma congolense to diminazene during the early phase of tsetse-transmitted infection in goats.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Diminazene; Drug Administration Schedule; Drug Resistance; Goat Diseases; Goats; Injections, Intramuscular; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1993 |
The influence of supplementation with cotton seed cake on the resistance of Ugandan goats to primary and secondary challenges with Trypanosoma congolense and on their response to treatment.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Diminazene; Food, Fortified; Goat Diseases; Goats; Hematocrit; Immunity, Innate; Male; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Uganda | 1997 |
The effect of diminazene aceturate on cholinesterase activity in dogs with canine babesiosis.
Topics: Acetylcholinesterase; Animals; Antiprotozoal Agents; Antipyrine; Babesiosis; Butyrylcholinesterase; Diminazene; Dog Diseases; Dogs; Erythrocytes; Random Allocation | 1997 |
Chemotherapy of surra in horses and mules with diminazene aceturate.
Topics: Animals; Antibodies, Protozoan; Creatine; Diminazene; Equidae; Female; Horse Diseases; Horses; Male; Pregnancy; Thailand; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2003 |
Effects of melarsamine hydrochloride (Cymelarsan) and diminazene aceturate (Berenil) on the pathology of experimental Trypanosoma brucei infection in red fronted gazelles (Gazella rufifrons).
Topics: Animals; Antelopes; Arsenicals; Diminazene; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2009 |
Efficacy of Cymelarsan and Diminasan against Trypanosoma equiperdum infections in mice and horses.
Topics: Animals; Arsenicals; Diminazene; Female; Horse Diseases; Horses; Mice; Parasitemia; Time Factors; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2010 |
Pharmacokinetics of diminazene diaceturate in healthy cats.
Topics: Animals; Antiprotozoal Agents; Area Under Curve; Cats; Chromatography, High Pressure Liquid; Diminazene; Female; Half-Life; Male | 2012 |
Is trypanocidal drug resistance a threat for livestock health and production in endemic areas? Food for thoughts from Sahelian goats infected by Trypanosoma vivax in Bobo Dioulasso (Burkina Faso).
Topics: Animals; Burkina Faso; Diminazene; Drug Resistance; Female; Goat Diseases; Goats; Hematocrit; Parasitemia; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
Effects of Trypanosoma brucei infection and diminazene aceturate therapy on testicular morphology and function of Nigerian local dogs.
Topics: Animals; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Male; Nigeria; Parasitemia; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 2013 |
Collateral benefits of restricted insecticide application for control of African trypanosomiasis on Theileria parva in cattle: a randomized controlled trial.
Topics: Animals; Cattle; Diminazene; Endemic Diseases; Female; Insecticides; Male; Pyrethrins; Theileria parva; Theileriasis; Trypanocidal Agents; Trypanosomiasis, African | 2014 |
Safety and efficacy of three trypanocides in confirmed field cases of trypanosomiasis in working equines in The Gambia: a prospective, randomised, non-inferiority trial.
Topics: Animals; Arsenicals; Diminazene; Equidae; Female; Gambia; Horse Diseases; Horses; Male; Phenanthridines; Prospective Studies; Random Allocation; Treatment Outcome; Triazines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2019 |
Efficacy of VERYL® in the treatment of cattle naturally infected with gastro-intestinal nematodes in Kenya.
Topics: Animals; Anthelmintics; Cattle; Cattle Diseases; Diminazene; Feces; Haemonchus; Kenya; Levamisole; Nematode Infections; Parasite Egg Count; Random Allocation; Trichostrongylus | 2020 |
Probiotic administration enhanced antitrypanosomal effects of diminazene aceturate in dogs experimentally infected with
Topics: Animals; Diminazene; Dogs; Female; Hemoglobins; Male; Parasitemia; Probiotics; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2022 |
506 other study(ies) available for diminazene and diminazene aceturate
| Article | Year |
|---|---|
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species.
Topics: Antimalarials; Cell Line; Curcumin; Diarylheptanoids; Humans; Inhibitory Concentration 50; Leishmania; Molecular Structure; Trypanocidal Agents; Trypanosoma | 2010 |
Studies on the induction of petite mutants in yeast by analogues of berenil. Characterization of three mutants resistant to the compound Hoe 15,030.
Topics: Diminazene; DNA Replication; DNA, Fungal; Drug Resistance, Microbial; Electron Transport; Genes, Fungal; Mitochondria; Mutagenesis; Saccharomyces cerevisiae; Structure-Activity Relationship | 1979 |
Therapeutic implications of Babesia canis infection in dogs.
Topics: Acute Disease; Amidines; Animals; Antiprotozoal Agents; Babesiosis; Benzamidines; Diminazene; Disseminated Intravascular Coagulation; Dog Diseases; Dogs; Drug Therapy, Combination; Infusions, Parenteral; Phenyl Ethers; Trypan Blue | 1979 |
Complement (C3) levels and activation in rabbits experimentally infected with Trypanosoma evansi.
Topics: Animals; Complement Activation; Complement C3; Diminazene; Female; Rabbits; Time Factors; Trypanocidal Agents; Trypanosomiasis | 1992 |
Multiple drug-resistant bovine trypanosomes in South Darfur Province, Sudan.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Phenanthridines; Sudan; Time Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Isolation of drug-resistant strains of Trypanosoma congolense from the lower Shabelle region of southern Somalia.
Topics: Animals; Animals, Domestic; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Recurrence; Somalia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Trypanosomiasis control in Boran cattle in Kenya: a comparison between chemoprophylaxis and a parasite detection and intravenous treatment method using isometamidium chloride.
Topics: Animals; Cattle; Diminazene; Drug Administration Schedule; Female; Injections, Intramuscular; Injections, Intravenous; Kenya; Male; Phenanthridines; Risk Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Pathogenesis of trypanosomiasis-induced glomerulonephritis in mice.
Topics: Animals; Antibodies; Basement Membrane; Diminazene; Female; Glomerulonephritis; Kidney Glomerulus; Mice; Mice, Inbred BALB C; Trypanosomiasis, African | 1992 |
Competitive parabolic inhibition of bovine trypsin by bis-benzamidines.
Topics: Animals; Cattle; Diminazene; In Vitro Techniques; Kinetics; Organoplatinum Compounds; Pentamidine; Structure-Activity Relationship; Substrate Specificity; Trypsin; Trypsin Inhibitors | 1992 |
A rapid, reliable method of evaluating growth and viability of intraerythrocytic protozoan hemoparasites using fluorescence flow cytometry.
Topics: Animals; Antiprotozoal Agents; Babesia bovis; Cattle; Cell Survival; Diminazene; DNA, Protozoan; Erythrocytes; Ethidium; Flow Cytometry; Parasitology; Phenanthridines | 1992 |
Trypanosomiasis in cattle in Gambia: incidence, prevalence and tsetse challenge.
Topics: Animals; Breeding; Cattle; Diminazene; Female; Gambia; Incidence; Insect Vectors; Male; Prevalence; Regression Analysis; Seasons; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
The rapid development of drug-resistance by Trypanosoma evansi in immunosuppressed mice.
Topics: Animals; Arsenicals; Diminazene; Drug Resistance; Immunosuppression Therapy; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 1992 |
Subcurative chemotherapy and fatal post-treatment reactive encephalopathies in African trypanosomiasis.
Topics: Adolescent; Adult; Animals; Arsenicals; Brain; Brain Diseases; Child; Child, Preschool; Diminazene; Female; Humans; Male; Mice; Nitroimidazoles; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Development of multiple drug resistance of Trypanosoma congolense in Zebu cattle under high natural tsetse fly challenge in the pastoral zone of Samorogouan, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Drug Resistance; Prevalence; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1992 |
Enhancement and alteration of bleomycin-catalyzed site-specific DNA cleavage by distamycin A and some minor groove binders.
Topics: Base Sequence; Bisbenzimidazole; Bleomycin; Diminazene; Distamycins; DNA; DNA Damage; Indoles; Molecular Sequence Data; Nucleic Acid Conformation | 1992 |
In vivo assessment of drug sensitivity of African trypanosomes using the akinetoplastic induction test.
Topics: Animals; Cattle; Diminazene; Mice; Phenanthridines; Rosaniline Dyes; Staining and Labeling; Toluidines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1992 |
Trypanosoma congolense: the use of 4,6-diamidino-2-phenylindole (DAPI) in the akinetoplastic induction sensitivity test.
Topics: Animals; Diminazene; Drug Resistance; Fluorescent Dyes; Indoles; Mice; Phenanthridines; Staining and Labeling; Trypanocidal Agents; Trypanosoma congolense | 1992 |
Incorporation of [3H]hypoxanthine by short-term cultured Theileria sergenti and its inhibition by drugs.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cattle; Cells, Cultured; Chloroquine; Diminazene; Dose-Response Relationship, Drug; Erythrocytes; Hypoxanthine; Hypoxanthines; Immune Sera; Pyrimethamine; Quinine; Theileria | 1992 |
Response of Trypanosoma congolense in goats to single and double treatment with diminazene aceturate.
Topics: Animals; Chromatography, High Pressure Liquid; Diminazene; Drug Administration Schedule; Goat Diseases; Goats; Hematocrit; Lymph Nodes; Male; Skinfold Thickness; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1992 |
An enzyme-linked immunosorbent assay (ELISA) for the detection of trypanosomal antigens in goat serum using a monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Diminazene; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Goats; Immunoglobulin M; Sensitivity and Specificity; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
DNA binding activity and inhibition of DNA-protein interactions. Differential effects of tetra-p-amidino-phenoxyneopentane and its 2'-bromo derivative.
Topics: Antigens, Viral; Base Sequence; Benzamidines; Cell Cycle; Cell Division; Diminazene; DNA-Binding Proteins; DNA, Viral; Dose-Response Relationship, Drug; Epstein-Barr Virus Nuclear Antigens; Humans; Molecular Sequence Data; Tumor Cells, Cultured | 1992 |
Trypanosoma congolense: manifestation of resistance to Berenil and Samorin in cloned trypanosomes isolated from Zambian cattle.
Topics: Animals; Cattle; Diminazene; Drug Tolerance; Genetic Variation; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, Bovine; Zambia | 1992 |
The use of azathioprine to ameliorate post-treatment encephalopathy associated with African trypanosomiasis.
Topics: Animals; Azathioprine; Brain Diseases; Diminazene; Disease Models, Animal; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosomiasis, African | 1992 |
Preliminary development of a live drug-controlled vaccine against bovine babesiosis using the Mongolian gerbil, Meriones unguiculatus.
Topics: Adjuvants, Immunologic; Animals; Babesia; Babesiosis; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Female; Gerbillinae; Imidocarb; Levamisole; Male; Oxytetracycline; Propionibacterium acnes; Protozoan Vaccines; Splenectomy; Vaccination; Virulence | 1992 |
Inhibition of enzymes of polyamine back-conversion by pentamidine and berenil.
Topics: Acetyltransferases; Animals; Diminazene; Humans; Kinetics; Leukemia L1210; Melanoma; Mice; Oxidoreductases Acting on CH-NH Group Donors; Pentamidine; Polyamine Oxidase | 1992 |
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO).
Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1992 |
Minor-groove width and accessibility in B-DNA drug and protein complexes.
Topics: Base Composition; Base Sequence; Diminazene; DNA; DNA-Binding Proteins; Macromolecular Substances; Molecular Sequence Data; Nucleic Acid Conformation; Structure-Activity Relationship | 1992 |
Trypanosoma congolense: the in vitro akinetoplastic induction sensitivity assay.
Topics: Animals; Diminazene; Drug Resistance; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense | 1992 |
Trypanocidal drugs and their effect on parasitaemia, specific IgG production and protective immunity in rats infected with Trypanosoma lewisi.
Topics: Animals; Antibodies, Protozoan; Diminazene; Ethidium; Female; Immunoglobulin G; Nifurtimox; Nitroimidazoles; Rats; Rats, Inbred F344; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis | 1992 |
Crystal structure of a berenil-d(CGCAAATTTGCG) complex. An example of drug-DNA recognition based on sequence-dependent structural features.
Topics: Base Sequence; Binding Sites; Computer Graphics; Crystallography; Diminazene; DNA; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship; Water | 1992 |
Evaluation of DL-alpha-difluoromethylornithine against susceptible and drug-resistant Trypanosoma brucei brucei.
Topics: Animals; Arsenicals; Culture Media; Diminazene; Drug Antagonism; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Humans; Immune Sera; Male; Mice; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Transmission of South American Trypanosoma vivax by the neotropical horsefly Tabanus nebulosus.
Topics: Animals; Cattle; Chagas Disease; Colombia; Diminazene; Diptera; Female; Insect Vectors; Male; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, Bovine | 1991 |
The effect of diminazene aceturate and isometamidium chloride on cultured procyclic forms of susceptible and drug-resistant Trypanosoma congolense.
Topics: Animals; Diminazene; Drug Resistance; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense | 1991 |
The effect of verapamil alone and in combination with trypanocides on multidrug-resistant Trypanosoma brucei brucei.
Topics: Animals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Verapamil | 1991 |
Cymelarsan in the treatment of buffaloes naturally infected with Trypanosoma evansi in south China.
Topics: Animals; Arsenicals; Buffaloes; Diminazene; Female; Injections, Intramuscular; Male; Muscles; Necrosis; Recurrence; Skin; Trypanocidal Agents; Trypanosomiasis | 1991 |
In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium.
Topics: Animals; Arsenicals; Diminazene; Female; Mice; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 1991 |
The minor-groove binding DNA-ligands netropsin, distamycin A and berenil cause polyploidisation via impairment of the G2 phase of the cell cycle.
Topics: Amidines; Bisbenzimidazole; Bromodeoxyuridine; Diminazene; Distamycins; DNA; Fibroblasts; Flow Cytometry; Guanidines; Humans; In Vitro Techniques; Interphase; Netropsin; Polyploidy; Pyrroles | 1990 |
H-NMR studies on d(GCTTAAGC)2 and its complex with berenil.
Topics: Base Sequence; Binding Sites; Diminazene; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1992 |
Studies on 1,3-diaryltriazene analogues of berenil: molecules with potential GC base-pair selectivity.
Topics: Base Composition; Base Sequence; Cytosine; Diminazene; Guanine; Molecular Sequence Data; Molecular Structure; Oligonucleotides; Triazenes; X-Ray Diffraction | 1991 |
Leishmania infantum: polyamine biosynthesis and levels during the growth of promastigotes.
Topics: Animals; Decarboxylation; Diminazene; Dogs; Eflornithine; Leishmania donovani; Methionine; Ornithine; Polyamines; Putrescine; Spermidine; Spermine; Trypanocidal Agents | 1991 |
Immunological changes in Babesia rodhaini infected BALB/c mice after treated with anti-babesial drug; diminazene diaceturate.
Topics: Acute Disease; Animals; Antibodies, Protozoan; Babesia; Babesiosis; Diminazene; Disease Models, Animal; Disease Susceptibility; Enzyme-Linked Immunosorbent Assay; Female; Immunity, Cellular; Immunotherapy, Adoptive; Mice; Mice, Inbred BALB C; Mice, Nude; Recurrence; Spleen; Thymus Gland | 1991 |
DL-alpha-difluoromethylornithine (DFMO)-Berenil combination: therapeutic and prophylactic activity against Trypanosoma brucei brucei infection in mice.
Topics: Animals; Diminazene; Drug Therapy, Combination; Eflornithine; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
In vitro drug sensitivity of Trypanosoma congolense isolates.
Topics: Animals; Culture Media; Diminazene; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense | 1991 |
Efficacy of combination of DFMO and diminazene aceturate in the treatment of late stage Trypanosoma brucei brucei infection in rats.
Topics: Animals; Brain Diseases; Diminazene; Drug Synergism; Drug Therapy, Combination; Eflornithine; Female; Male; Rats; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1991 |
Therapeutic effect of Berenil and Samorin in mice infected with four trypanosome populations isolated from Zambian cattle.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Zambia | 1991 |
Susceptibility of N'Dama and Boran cattle to sequential challenges with tsetse-transmitted clones of Trypanosoma congolense.
Topics: Anemia; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Body Weight; Cattle; Diminazene; Disease Susceptibility; Female; Hematocrit; Insect Vectors; Male; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Homidium bromide as a chemoprophylactic for cattle trypanosomiasis in Kenya.
Topics: Animals; Cattle; Diminazene; Ethidium; Hematocrit; Kenya; Male; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Weight Gain | 1990 |
Trypanosoma brucei evansi: dyskinetoplasia and loss of infectivity after long-term in vitro cultivation.
Topics: Animals; Diminazene; DNA, Circular; DNA, Kinetoplast; Female; Male; Mice; Microscopy, Electron; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1990 |
Residues of some veterinary drugs in animals and foods. Joint FAO/WHO Expert Committee on Food Additives.
Topics: Albendazole; Anabolic Agents; Animals; Antiprotozoal Agents; Dimetridazole; Diminazene; Drug Residues; Food Contamination; Humans; Ipronidazole; Metronidazole; Molecular Structure; Phenanthridines; Ronidazole; Sulfamethazine; Sulfathiazole; Sulfathiazoles; Trenbolone Acetate; Trypanocidal Agents | 1990 |
Interaction of berenil with the EcoRI dodecamer d(CGCGAATTCGCG)2 in solution studied by NMR.
Topics: Base Sequence; Deoxyribonuclease EcoRI; Diminazene; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship; Temperature | 1991 |
Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Genetic Variation; Isoenzymes; Mice; Phenanthridines; Phenotype; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1991 |
Cellular phenotypes in Trypanosoma congolense infected sheep: the local skin reaction.
Topics: Animals; Antibodies, Monoclonal; Diminazene; Immunophenotyping; Lymphocyte Subsets; Sheep; Sheep Diseases; Skin; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Action of methylglyoxal bis (guanyl hydrazone) and related antiprotozoals on Acanthamoeba culbertsoni.
Topics: Acanthamoeba; Animals; Antiprotozoal Agents; Diminazene; Mitoguazone; Polyamines | 1990 |
Multiple superovulations in N'Dama heifers.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Embryo Transfer; Estrus; Female; Follicle Stimulating Hormone; Pregnancy; Superovulation; Time Factors; Trypanocidal Agents; Trypanosomiasis | 1990 |
Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs.
Topics: Animals; Diminazene; DNA Topoisomerases, Type I; DNA, Circular; DNA, Kinetoplast; Ethidium; Molecular Structure; Pentamidine; Phenanthridines; Restriction Mapping; Trypanocidal Agents; Trypanosoma | 1990 |
Netropsin, distamycin and berenil interact differentially with a high-affinity binding site for the high mobility group protein HMG-I.
Topics: Amidines; Antiprotozoal Agents; Base Sequence; Binding Sites; Deoxyribonuclease I; Diminazene; Distamycins; DNA; Guanidines; High Mobility Group Proteins; Molecular Sequence Data; Netropsin; Plasmids; Pyrroles | 1990 |
Interaction of berenil with the tyrT DNA sequence studied by footprinting and molecular modelling. Implications for the design of sequence-specific DNA recognition agents.
Topics: Amidines; Base Sequence; Deoxyribonuclease I; Diminazene; DNA; Hydroxides; Hydroxyl Radical; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Nucleotide Mapping; Promoter Regions, Genetic; Thermodynamics | 1990 |
Transcription factor TFIIIA stimulates DNA supercoiling promoted by a fractionated cell-free extract from Xenopus laevis.
Topics: Adenosine Triphosphate; Animals; Cell-Free System; Chromatography, Gel; Diminazene; DNA, Superhelical; In Vitro Techniques; Kinetics; Oocytes; Plasmids; Ribonucleotides; Teniposide; Transcription Factor TFIIIA; Transcription Factors; Xenopus laevis | 1990 |
Effects of the combination of DL-alpha-difluoromethylornithine and diminazene aceturate in Trypanosoma congolense infection of dogs.
Topics: Animals; Diminazene; Dog Diseases; Dogs; Drug Therapy, Combination; Eflornithine; Female; Male; Trypanosoma congolense; Trypanosomiasis, African | 1990 |
Teratological assessment of the antiprotozoal, diminazene diaceturate, in rats.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Body Weight; Diminazene; Female; Fetal Resorption; Fetus; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Teratogens | 1990 |
A drug incubation infectivity test (DIIT) for assessing resistance in trypanosomes.
Topics: Amidines; Animals; Diminazene; Drug Resistance; Female; Mice; Mice, Inbred BALB C; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis | 1990 |
Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding.
Topics: Amidines; Base Composition; Base Sequence; Crystallization; Diminazene; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Trypanocidal Agents; X-Ray Diffraction | 1990 |
Trypanosoma congolense: an in vitro assay to distinguish drug-resistant from drug-sensitive populations.
Topics: Amidines; Animals; Diminazene; Drug Resistance; Hypoxanthines; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense | 1990 |
Structural analysis of d(GCAATTGC)2 and its complex with berenil by nuclear magnetic resonance spectroscopy.
Topics: Amidines; Diminazene; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oligodeoxyribonucleotides; Structure-Activity Relationship | 1990 |
The binding of nonintercalative drugs to alternating DNA sequences.
Topics: Base Sequence; Bisbenzimidazole; Diminazene; Distamycins; DNA; Netropsin; Nucleic Acid Conformation; Poly dA-dT; Polydeoxyribonucleotides; Thermodynamics | 1989 |
Berenil-induced undercondensation in human heterochromatin.
Topics: Amidines; Blotting, Southern; Chromosome Aberrations; Chromosomes; Diminazene; Heterochromatin; Humans; Karyotyping; Male; Metaphase; Nucleic Acid Hybridization; Polymorphism, Genetic; Quinacrine Mustard; Staining and Labeling; Y Chromosome | 1989 |
Putrescine transport system in Leishmania infantum promastigotes.
Topics: Amino Acids; Animals; Biological Transport, Active; Diminazene; Eflornithine; Hydrogen-Ion Concentration; Leishmania donovani; Polyamines; Putrescine; Temperature | 1989 |
In vitro drug sensitivity test for Trypanosoma brucei subgroup bloodstream trypomastigotes.
Topics: Animals; Arsenicals; Diminazene; Hypoxanthine; Hypoxanthines; Leucine; Pentamidine; Phenanthridines; Suramin; Thymidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1989 |
Natural and acquired resistance to Trypanosoma vivax in cattle.
Topics: Animals; Cattle; Diminazene; Gastrointestinal Hemorrhage; Goats; Immunity, Active; Immunity, Innate; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1989 |
Trypanosoma congolense: erythrocyte indices, plasma iron turnover and effects of treatment in infected cattle.
Topics: Anemia, Hemolytic; Animals; Cattle; Cattle Diseases; Diminazene; Erythrocyte Count; Erythrocyte Indices; Hematocrit; Iron; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1989 |
Effects of trypanosomal infection on the pharmacokinetics of diminazene aceturate in dogs.
Topics: Amidines; Animals; Diminazene; Dog Diseases; Dogs; Injections, Intravenous; Trypanosoma brucei brucei; Trypanosomiasis | 1989 |
Effect of repeated administration of berenil on urinary enzyme excretion with corresponding tissue pattern in rats.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Enzymes; Injections, Subcutaneous; Kidney; Male; Rats; Time Factors | 1989 |
Use of extracts of Picralima nitida bark in the treatment of experimental trypanosomiasis: a preliminary study.
Topics: Animals; Diminazene; Drug Evaluation, Preclinical; Female; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1989 |
The influence of Trypanosoma congolense infection on the disposition kinetics of diminazene aceturate in the dog.
Topics: Amidines; Animals; Diminazene; Dog Diseases; Dogs; Injections, Intravenous; Male; Regression Analysis; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1989 |
Bovine trypanosomiasis in southern Tanzania: investigation into the incidence of infection and duration of chemoprophylaxis.
Topics: Age Factors; Amidines; Animal Husbandry; Animals; Cattle; Cohort Studies; Diminazene; Injections, Intramuscular; Phenanthridines; Tanzania; Time Factors; Trypanosoma congolense; Trypanosomiasis, Bovine | 1989 |
Studies on DNA topoisomerase activity during in vitro chromatin assembly.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Chromatin; Diminazene; DNA Topoisomerases, Type I; DNA, Superhelical; In Vitro Techniques; Nalidixic Acid; Nucleosomes; Oxolinic Acid; Plasmids; Xenopus laevis | 1988 |
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis.
Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies | 1987 |
The effect of the trypanocidal drugs berenil and samorin on infections of Glossina morsitans centralis by Trypanosoma congolense.
Topics: Amidines; Animals; Diminazene; Insect Vectors; Male; Mice; Mice, Inbred ICR; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1987 |
The relapse of Trypanosoma brucei brucei infections after chemotherapy in rabbits.
Topics: Amidines; Animals; Diminazene; Female; Male; Mice; Rabbits; Recurrence; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
Berenil (diminazene aceturate)-resistant Trypanosoma congolense in cattle under natural tsetse challenge at Kibaha, Tanzania.
Topics: Amidines; Animals; Cattle; Diminazene; Drug Resistance; Mice; Phenanthridines; Tanzania; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1988 |
Studies on mitochondrial type I topoisomerase and on its function.
Topics: Animals; Chromatography, Affinity; Dimethyl Sulfoxide; Diminazene; DNA Topoisomerases, Type I; DNA, Mitochondrial; DNA, Superhelical; Intracellular Membranes; L Cells; Mice; Mitochondria; Rats; Topoisomerase I Inhibitors | 1985 |
Antibiotics which can alter the rotational orientation of nucleosome core DNA.
Topics: Anti-Bacterial Agents; Dactinomycin; Diminazene; DNA; Netropsin; Nogalamycin; Nucleosomes; Plasmids | 1986 |
Vaccinia virus encapsidates a novel topoisomerase with the properties of a eucaryotic type I enzyme.
Topics: Adenosine Triphosphate; Aminocoumarins; Cells; Coumarins; Diminazene; DNA Topoisomerases, Type I; DNA, Superhelical; Eukaryotic Cells; Magnesium; Molecular Weight; Nalidixic Acid; Novobiocin; Vaccinia virus | 1987 |
Comparison of binding sites in DNA for berenil, netropsin and distamycin. A footprinting study.
Topics: Amidines; Base Sequence; Binding Sites; Deoxyribonuclease I; Diminazene; Distamycins; DNA; Guanidines; Micrococcal Nuclease; Netropsin; Pyrroles | 1987 |
Inhibition of diamine oxidase and S-adenosylmethionine decarboxylase by diminacene aceturate (berenil).
Topics: Adenosylmethionine Decarboxylase; Amidines; Amine Oxidase (Copper-Containing); Animals; Antiprotozoal Agents; Carboxy-Lyases; Diminazene; Dose-Response Relationship, Drug; Kinetics; Male; Rats; Rats, Inbred Strains | 1986 |
A simple epidemiological method for animal trypanosomiasis to provide relevant data for effective financial decision-making.
Topics: Age Factors; Animals; Body Weight; Cattle; Cost-Benefit Analysis; Diminazene; Female; Kenya; Male; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1986 |
The alternative pathway of complement in sheep during the course of infection with Trypanosoma congolense and after Berenil treatment.
Topics: Animals; Antibodies, Bacterial; Brucella abortus; Complement Activation; Complement C3; Complement Factor B; Complement Pathway, Alternative; Diminazene; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1986 |
Inhibition of diamine oxidase of rat small intestine by pentamidine and berenil (diminazene aceturate).
Topics: Amidines; Amine Oxidase (Copper-Containing); Animals; Diminazene; Intestine, Small; Pentamidine; Rats; Structure-Activity Relationship | 1987 |
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Combinations; Eflornithine; Female; Immunosuppression Therapy; Pneumonia, Pneumocystis; Random Allocation; Rats; Rats, Inbred Strains; Sulfamethoxazole; Suramin; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Effects of trypanocides on Herpetosoma in a mammalian feeder layer cell culture.
Topics: Animals; Arvicolinae; Cells, Cultured; Diminazene; Ethidium; Fibroblasts; Phenanthridines; Quinolinium Compounds; Trypanocidal Agents; Trypanosomatina | 1988 |
Additive effects of tetrocarcin-A and diminazene aceturate concurrently administered against Babesia rodhaini-inoculated mice.
Topics: Amidines; Aminoglycosides; Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Babesiosis; Diminazene; Drug Combinations; Female; Mice | 1988 |
Extravascular foci of Trypanosoma vivax in goats: the central nervous system and aqueous humor of the eye as potential sources of relapse infections after chemotherapy.
Topics: Animals; Aqueous Humor; Central Nervous System Diseases; Cerebrospinal Fluid; Choroid Plexus; Diminazene; Goats; Male; Mice; Recurrence; Trypanosoma; Trypanosomiasis, African | 1988 |
Studies on binding of berenil to microsomal protein and its significance with respect to microsomal metabolism of trypanocidal drug.
Topics: Amidines; Animals; Binding Sites; Diminazene; Male; Microsomes, Liver; Oxidoreductases; Protein Binding; Rats; Rats, Inbred Strains; Trypanocidal Agents | 1988 |
Daily efficacy variation of diminazene diaceturate in mice infected with Babesia rodhaini.
Topics: Amidines; Animals; Antiprotozoal Agents; Babesiosis; Circadian Rhythm; Diminazene; Female; Mice; Mice, Inbred ICR | 1988 |
Attempts to protect goats against challenge with Trypanosoma vivax by initiation of primary infections with large numbers of metacyclic trypanosomes.
Topics: Animals; Antibodies, Protozoan; Diminazene; Goats; Male; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 1988 |
Enhanced resistance of highly susceptible Balb/c mice to infection with Trypanosoma congolense after infection and cure.
Topics: Agglutination Tests; Animals; Antibodies, Protozoan; Antigenic Variation; Diminazene; Female; Fluorescent Antibody Technique; Immune Sera; Immunity, Active; Immunization, Passive; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1987 |
Ascaris suum and Onchocerca volvulus: S-adenosylmethionine decarboxylase.
Topics: Adenosylmethionine Decarboxylase; Animals; Ascaris; Carboxy-Lyases; Chromatography, Gel; Diminazene; Enzyme Activation; Female; Magnesium; Male; Mitoguazone; Onchocerca; Pentamidine; Polyethylene Glycols; Putrescine | 1988 |
Susceptibility of goats to tsetse-transmitted challenge with Trypanosoma vivax from East and West Africa.
Topics: Africa, Eastern; Africa, Western; Animals; Chronic Disease; Diminazene; Disease Susceptibility; Goats; Immunity, Active; Insect Vectors; Male; Recurrence; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Tsetse Flies; Virulence | 1988 |
Relapses in dogs experimentally infected with Trypanosoma brucei and treated with diminazene aceturate or isometamidium chloride.
Topics: Alanine Transaminase; Amidines; Animals; Antibodies, Protozoan; Aspartate Aminotransferases; Diminazene; Dog Diseases; Dogs; Fever; Hematocrit; Hemoglobins; Phenanthridines; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1988 |
The effect of structural changes in a polyamine backbone on its DNA-binding properties.
Topics: Animals; Binding, Competitive; Cattle; Diminazene; DNA; Ethidium; Hydrogen Bonding; Putrescine; Spectrometry, Fluorescence; Spermidine; Spermine | 1988 |
Babesiosis in a litter of pups.
Topics: Animals; Antiprotozoal Agents; Babesiosis; Diminazene; Dog Diseases; Dogs; Erythrocyte Count; Erythrocytes; Female; Male; Reticulocytes; Thrombocytopenia; Tick Infestations | 1988 |
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense.
Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei | 1987 |
The treatment of Trypanosoma (Nannomonas) simiae in pigs with diminazene aceturate in combination with a 5-substituted 2-nitroimidazole compound (Ro 15-0216).
Topics: Acetanilides; Amidines; Animals; Diminazene; Drug Therapy, Combination; Female; Male; Mice; Nitroimidazoles; Swine; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 1987 |
The sensitivity to trypanocidal drugs of Trypanosoma vivax isolated in Kenya and Somalia.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Male; Phenanthridines; Quinolinium Compounds; Somalia; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Role of mitochondrial DNA in cell death induced by 125I decay.
Topics: Animals; Cell Survival; Cricetinae; Cricetulus; Diminazene; DNA; DNA, Mitochondrial; Idoxuridine; Iodine Radioisotopes | 1986 |
Control of trypanodestructive antibody responses and parasitemia in mice infected with Trypanosoma (Duttonella) vivax.
Topics: Animals; Antibodies; Antibody Formation; B-Lymphocytes; Cyclophosphamide; Diminazene; Lymphocyte Activation; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Spleen; T-Lymphocytes; Trypanosoma; Trypanosomiasis | 1986 |
The crystal structure of the DNA-binding drug berenil: molecular modelling studies of berenil-DNA complexes.
Topics: Amidines; Crystallization; Diminazene; DNA; Energy Metabolism; Models, Molecular; Molecular Conformation | 1987 |
Trypanosoma congolense: host responses following tsetse transmitted infection of Kilifi isolates in goats.
Topics: Animals; Antibody Formation; Antigens, Protozoan; Cattle; Diminazene; Glucose-6-Phosphate Isomerase; Goats; Isoenzymes; Kenya; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1987 |
Putrescine-activated S-adenosylmethionine decarboxylase from Acanthamoeba culbertsoni.
Topics: Adenosylmethionine Decarboxylase; Amoeba; Animals; Carboxy-Lyases; Cell-Free System; Diminazene; Enzyme Activation; Kinetics; Metals; Mitoguazone; Molecular Weight; Pentamidine; Putrescine | 1987 |
Failure of berenil therapy to eliminate early infections with a strain of Trypanosoma brucei from West Abaya, Ethiopia.
Topics: Amidines; Animals; Cattle; Diminazene; Ethiopia; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
The fragile site (16)(q22). II. Sister chromatid exchanges.
Topics: Bromodeoxyuridine; Chromosome Banding; Chromosome Fragile Sites; Chromosome Fragility; Chromosomes, Human, Pair 16; Diminazene; Female; Heterozygote; Humans; Karyotyping; Lymphocytes; Male; Sister Chromatid Exchange | 1987 |
[Incidence of bovine trypanosomiasis on the ranch at Madina-Diassa (Mali). Curative treatment of ill animals].
Topics: Animals; Cattle; Diminazene; Female; Mali; Trypanocidal Agents; Trypanosomiasis, Bovine | 1986 |
Effect of tetracycline administration on the efficacy of diminazene aceturate therapy and prophylaxis in Trypanosoma brucei infections of mice.
Topics: Amidines; Animals; Diminazene; Drug Therapy, Combination; Mice; Oxytetracycline; Rolitetracycline; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Development of Trypanosoma brucei in suckling mouse brain following intracerebral injection.
Topics: Animals; Animals, Suckling; Brain; Diminazene; Injections, Intraventricular; Mice; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Trypanosoma theileri Laveran, 1902, in naturally and experimentally infected cattle: parasite isolation, serological and cellular reactions and Berenil sensitivity.
Topics: Amidines; Animals; Antibodies, Protozoan; Cattle; Diminazene; Immunity, Cellular; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1987 |
Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse.
Topics: Animals; Antibody Formation; Diminazene; Goats; Male; Neutralization Tests; Skin; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 1986 |
[Duration of the preventive action of diminazene aceturate on experimental infection of NMRI mice with metacyclic forms of Trypanosoma brucei brucei].
Topics: Amidines; Animals; Diminazene; Female; Mice; Mice, Inbred Strains; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Regulation of parasite-specific antibody responses in resistant (C57BL/6) and susceptible (C3H/HE) mice infected with Trypanosoma (trypanozoon) brucei brucei.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Diminazene; Disease Susceptibility; Female; Immune Tolerance; Immunity, Innate; Immunoglobulins; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Microscopy, Electron; Spleen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Male; Mitoguazone; Pentamidine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma brucei brucei | 1986 |
Ejaculate characteristics of sheep infected with Trypanosoma brucei and T vivax: changes caused by treatment with diminazene aceturate.
Topics: Animals; Diminazene; Male; Semen; Sheep; Sheep Diseases; Sperm Count; Sperm Motility; Spermatozoa; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 1987 |
Induction of protective immunity in cattle by tsetse-transmitted cloned isolates of Trypanosoma congolense.
Topics: Animals; Antibody Formation; Cattle; Diminazene; Female; Hypersensitivity; Male; Mice; Mice, Inbred A; Neutralization Tests; Skin; Skin Tests; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1985 |
An assay for screening drugs against animal-infective bloodstream forms of Trypanosoma brucei brucei in vitro.
Topics: Animals; Diminazene; Mice; Parasitology; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei | 1985 |
Irreversible inhibition of putrescine-stimulated S-adenosyl-L-methionine decarboxylase by berenil and pentamidine.
Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Diphenylamine; Liver; Pentamidine; Pseudomonas aeruginosa; Putrescine; Rats; S-Adenosylmethionine; Saccharomyces cerevisiae | 1985 |
Relapse infection after chemotherapy in goats experimentally infected with Trypanosoma brucei: pathological changes in central nervous system.
Topics: Amidines; Animals; Blood-Brain Barrier; Central Nervous System; Choroiditis; Diminazene; Goats; Male; Meningitis; Orchiectomy; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1986 |
Antibody responses in resistant and susceptible inbred mice infected with Trypanosoma congolense.
Topics: Animals; Antibody Specificity; Antigens, Protozoan; Antigens, Surface; Diminazene; Disease Susceptibility; Female; Glycoproteins; Immunity, Innate; Immunoglobulin G; Immunoglobulin M; Male; Membrane Proteins; Mice; Mice, Inbred A; Mice, Inbred C57BL; Rats; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1986 |
Maternally derived immunity in young mice to infection with Trypanosoma brucei and its potentiation by Berenil chemotherapy.
Topics: Age Factors; Amidines; Animals; Animals, Suckling; Colostrum; Diminazene; Female; Immunization, Passive; Mice; Pregnancy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |
Irreversible binding of berenil, a trypanocidal drug to blood proteins.
Topics: Amidines; Blood Proteins; Diminazene; Humans; Protein Binding; Trypanocidal Agents | 1985 |
Trypanosoma brucei: five commonly used trypanocides assayed in vitro with a mammalian feeder layer system for cultivation of bloodstream forms.
Topics: Animals; Cattle; Cells, Cultured; Diminazene; Dose-Response Relationship, Drug; Melarsoprol; Phenanthridines; Quinolinium Compounds; Trypanocidal Agents; Trypanosoma brucei brucei | 1985 |
Trypanosoma musculi persisting in the kidneys of mice are responsible for maintaining the host immunity.
Topics: Animals; Antibodies; Diminazene; Kidney; Male; Mice; Mice, Inbred CBA; Trypanocidal Agents; Trypanosomiasis | 1985 |
Immunopathological aspects of trypanosomal meningoencephalitis in vervet monkeys after relapse following Berenil treatment.
Topics: Amidines; Animals; Antigen-Antibody Complex; Autoantibodies; Blood-Brain Barrier; Brain; Chlorocebus aethiops; Diminazene; Immunoglobulin G; Immunoglobulin M; Meningoencephalitis; Recurrence; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1985 |
Comparative studies of the effects of quinuronium sulfate and diminazene diaceturate in sheep.
Topics: Amidines; Animals; Antiprotozoal Agents; Ataxia; Behavior, Animal; Bilirubin; Blood Urea Nitrogen; Creatine Kinase; Diminazene; L-Lactate Dehydrogenase; Male; Quinolinium Compounds; Sheep; Tremor; Urea | 1985 |
Studies in cattle on the disposition of the anti-trypanosomal drug diminazene diaceturate (Berenil).
Topics: Amidines; Animals; Autoradiography; Biological Availability; Carbon Radioisotopes; Cattle; Diminazene; Feces; Half-Life; Injections, Intramuscular; Kinetics; Male; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution; Trypanocidal Agents | 1985 |
The solvation contribution to the binding energy of DNA with non-intercalating antibiotics.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Diminazene; Distamycins; DNA; Hydrogen Bonding; Netropsin; Pyridinium Compounds; Solvents; Stilbamidines | 1984 |
Relapse of monomorphic and pleomorphic Trypanosoma brucei infections in the mouse after chemotherapy.
Topics: Amidines; Animals; Brain; Diminazene; Female; Mice; Recurrence; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Chemotherapy of Trypanosoma brucei in mice with diminazene aceturate. Variation in the aparasitaemic period over 5 years.
Topics: Amidines; Animals; Blood; Diminazene; Freezing; Mice; Preservation, Biological; Time Factors; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Lymphocyte function in experimental African trypanosomiasis. VII. Loss of antigen-nonspecific suppressor-T-cell activity.
Topics: Animals; Antibody Formation; Antigens, Ly; Diminazene; Immune Tolerance; Male; Mice; Mice, Inbred C57BL; Spleen; T-Lymphocytes, Regulatory; Trypanosoma; Trypanosomiasis, African | 1984 |
DNA topoisomerase I from mitochondria of Xenopus laevis oocytes.
Topics: Animals; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Cytosol; Digitonin; Diminazene; DNA Topoisomerases, Type I; Ethidium; Female; Mitochondria; Oocytes; Ovum; Xenopus laevis | 1981 |
Properties of a purified nuclear topoisomerase from L1210 cells.
Topics: Animals; Cell Nucleus; Diminazene; DNA Topoisomerases, Type I; Histones; Leukemia L1210; Mice; Structure-Activity Relationship; Topoisomerase I Inhibitors | 1983 |
The role of the nuclear gene "mitochondrial mutability control" (MMC1) in the process of mutability of the mitochondrial genome by different mutagens in Saccharomyces cerevisiae.
Topics: Acriflavine; Cell Nucleus; Diminazene; DNA, Fungal; DNA, Mitochondrial; Erythromycin; Ethidium; Fluorouracil; Gene Expression Regulation; Manganese; Mutagens; Rosaniline Dyes; Saccharomyces cerevisiae | 1983 |
[Serodiagnosis and therapy control of equine piroplasmosis by CFT and IFAT].
Topics: Animals; Antibody Formation; Antiprotozoal Agents; Babesia; Babesiosis; Complement Fixation Tests; Diminazene; Female; Fluorescent Antibody Technique; Horse Diseases; Horses; Male | 1984 |
Chemoprophylaxis with diminazene aceturate in experimental Babesia bigemina infection in cattle.
Topics: Amidines; Animals; Antiprotozoal Agents; Babesiosis; Blood; Body Temperature; Cattle; Cattle Diseases; Diminazene; Injections, Intramuscular; Male; Time Factors | 1984 |
Retrospective long-term study of effects of berenil by follow-up of patients treated since 1965.
Topics: Adolescent; Adult; Amidines; Cerebrospinal Fluid; Child; Child, Preschool; Diminazene; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pregnancy; Pregnancy Complications, Infectious; Retrospective Studies; Trypanocidal Agents; Trypanosomiasis, African; Uganda; Urine | 1984 |
The effect of halofuginone, Wellcome 993 C, oxytetracycline, and diminazene diaceturate on Babesia equi-infected lymphoblastoid cell cultures.
Topics: Amidines; Animals; Antiprotozoal Agents; Babesia; Cell Line; Diminazene; DNA; Lymphocytes; Naphthoquinones; Oxytetracycline; Piperidines; Quinazolines; Quinazolinones; Thymidine | 1984 |
Diminazene/Berenil: bioavailability and disposition in dairy goats.
Topics: Amidines; Animals; Biological Availability; Diminazene; Goats | 1984 |
Trypanocidal and antitumour activity of platinum-metal and platinum-metal-drug dual-function complexes.
Topics: Animals; Antineoplastic Agents; Cisplatin; Diminazene; Mice; Mice, Inbred Strains; Platinum; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma | 1984 |
Persistence of Berenil in cattle.
Topics: Amidines; Animals; Cattle; Diminazene; Kenya; Male; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
Observation on drug resistance of Trypanosoma (Nannomonas) congolense and Trypanosoma (Duttonella) vivax in cattle at a feedlot in the Northern Ivory Coast.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Male; Phenanthridines; Quaternary Ammonium Compounds; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1983 |
The use of the 2 substituted 5-nitroimidazole, Fexinidazole (Hoe 239) in the treatment of chronic T. brucei infections in mice.
Topics: Animals; Antiprotozoal Agents; Chronic Disease; Diminazene; Drug Therapy, Combination; Female; Mice; Mice, Inbred Strains; Nitroimidazoles; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies in rabbits on the disposition and trypanocidal activity of the anti-trypanosomal drug, diminazene aceturate (Berenil).
Topics: Amidines; Animals; Diminazene; Kinetics; Rabbits; Tissue Distribution; Trypanosomiasis, African | 1983 |
Chemotherapy of Babesia divergens in the gerbil, Meriones unguiculatus.
Topics: Animals; Antiprotozoal Agents; Babesiosis; Carbanilides; Diminazene; Disease Models, Animal; Female; Gerbillinae; Imidocarb; Male; Quinolinium Compounds; Urea | 1983 |
A theoretical study of the nonintercalative binding of berenil and stilbamidine to double-stranded (dA-dT)n oligomers.
Topics: Amidines; Chemical Phenomena; Chemistry; Diminazene; Models, Molecular; Nucleic Acid Conformation; Stilbamidines; Structure-Activity Relationship; Trypanocidal Agents | 1984 |
Maintaining zebu Maure cattle in a tsetse infested area of Mali.
Topics: Animals; Body Weight; Cattle; Diminazene; Female; Male; Mali; Phenanthridines; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1984 |
Response of the rat's hepatic drug-metabolizing enzyme system to chemotherapy of Trypanosoma b. brucei infections with Berenil and Suramin.
Topics: Amidines; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Diminazene; Female; Glutamate Dehydrogenase; Kinetics; L-Lactate Dehydrogenase; Liver; Microsomes, Liver; Phospholipids; Rats; Suramin; Trypanosoma brucei brucei; Trypanosomiasis, African | 1984 |
The possible use of Trypanosoma musculi infection in mice as a screening test for potential Trypanosoma cruzi-active drugs.
Topics: Animals; Chagas Disease; Diminazene; Drug Evaluation, Preclinical; Ethidium; Female; Kidney; Mice; Nifurtimox; Nitroimidazoles; Phenanthridines; Trypanocidal Agents; Trypanosomiasis | 1982 |
Relapsed parasitaemia following chemotherapy of chronic T. brucei infections in mice and its relation to cerebral trypanosomes.
Topics: Animals; Antiprotozoal Agents; Brain; Chronic Disease; Diminazene; Mice; Recurrence; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Studies of choroid plexus involvement in chronic infections of mice with Trypanosoma brucei gambiense.
Topics: Animals; Antiprotozoal Agents; Choroid Plexus; Chronic Disease; Diminazene; Mice; Nifurtimox; Trypanosoma brucei brucei; Trypanosomiasis, African | 1983 |
Clinical observations on Babesia gibsoni and Babesia canis infections in dogs.
Topics: Animals; Babesiosis; Diminazene; Dog Diseases; Dogs; Erythrocytes; Female; Japan; Pentamidine | 1982 |
Quantitative methods in the study of the pathogenesis of haemoprotozoal diseases.
Topics: Analysis of Variance; Animals; Blood Cell Count; Capillaries; Cattle; Diminazene; Hematocrit; Hemoglobins; Mathematics; Parasitology; Statistics as Topic; Theileriasis; Time Factors; Trypanosoma; Trypanosomiasis; Trypanosomiasis, Bovine | 1982 |
Delay in resolution of trypanosome-induced genital lesions in male rabbits infected with Trypanosoma brucei and treated with diminazene aceturate.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Genital Diseases, Male; Genitalia, Male; Male; Rabbits; Scrotum; Testis; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
Interference in the establishment of superinfections with Trypanosoma congolense in cattle.
Topics: Animals; Antibodies; Antiprotozoal Agents; Cattle; Diminazene; Immunity; Immunization; Mice; Mice, Inbred Strains; Trypanosoma; Trypanosomiasis, Bovine | 1982 |
Trypanosomiasis in a dog imported in The Netherlands.
Topics: Animals; Animals, Domestic; Antiprotozoal Agents; Diagnosis, Differential; Diminazene; Dog Diseases; Dogs; Nepal; Trypanosomiasis | 1982 |
Pharmacokinetics and efficacy of the trypanocide diminazene aceturate (Berenil) in rabbits.
Topics: Amidines; Animals; Antiprotozoal Agents; Diminazene; Kinetics; Rabbits; Trypanosomiasis, African | 1982 |
Diminazene aceturate in the treatment of experimentally induced Trypanosoma brucei brucei infection in domestic chickens.
Topics: Amidines; Animals; Antiprotozoal Agents; Chickens; Diminazene; Humans; Mice; Poultry Diseases; Trypanosoma brucei brucei; Trypanosomiasis, African | 1982 |
The efficacy of berenil (diminazene aceturate) against Trypanosoma evansi infection in mice.
Topics: Amidines; Animals; Antiprotozoal Agents; Blood; Diminazene; Female; Male; Mice; Mice, Inbred Strains; Species Specificity; Trypanosoma; Trypanosomiasis, African | 1982 |
Pharmacotherapeutics of drugs used in treatment of anaplasmosis and babesiosis.
Topics: Amidines; Anaplasmosis; Animals; Babesiosis; Carbanilides; Cattle; Cattle Diseases; Diminazene; Imidocarb; Tetracyclines | 1980 |
Imidocarb: a chemoprophylactic experiment with Babesia canis.
Topics: Amidines; Animals; Antiprotozoal Agents; Babesiosis; Carbanilides; Diminazene; Dog Diseases; Dogs; Female; Hematocrit; Imidocarb; Injections, Intramuscular; Injections, Subcutaneous; Male | 1981 |
[Trypanosoma evansi: microbiological and biological behavior before and after Berenil administration].
Topics: Amidines; Animals; Diminazene; Female; Mice; Trypanosoma; Trypanosomiasis | 1981 |
'Berenil' and nitroimidazole combinations in the treatment of Trypanosoma brucei infection with central nervous system involvement.
Topics: Amidines; Animals; Benzamidines; Central Nervous System Diseases; Diminazene; Ethidium; Female; Isoxazoles; Mice; Nitroimidazoles; Phenanthridines; Ronidazole; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1980 |
Hemolytic complement and serum C3 levels in Zebu cattle infected with Trypanosoma congolense and Trypanosoma vivax and the effect of trypanocidal treatment.
Topics: Amidines; Animals; Cattle; Complement C3; Complement System Proteins; Diminazene; Male; Trypanocidal Agents; Trypanosomiasis, Bovine | 1980 |
Differentiation promoting factors induced in Acanthamoeba by inhibitors of mitochondrial macromolecule synthesis.
Topics: Amidines; Amoeba; Animals; Cell Differentiation; Chloramphenicol; Culture Media; Diminazene; Erythromycin; Ethidium; Mitochondria | 1980 |
Berenil induces the complete loss of kinetoblast DNA sequences in Trypanosoma equiperdum.
Topics: Amidines; Animals; Base Sequence; Diminazene; DNA; DNA, Circular; Kinetics; Nucleic Acid Renaturation; Rats; Trypanosoma | 1980 |
The quantitation of trypanosoma congolense in calves. III. A quantitative comparison of trypanosomes in jugular vein and microvasculature and tests of dispersing agents.
Topics: Animals; Animals, Newborn; Brain; Capillaries; Cattle; Dexamethasone; Diminazene; Jugular Veins; Liver; Male; Muscles; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1980 |
A bioequivalence and pharmacokinetic evaluation of two commercial diminazene aceturate formulations administered intramuscularly to cattle.
Topics: Animals; Antiprotozoal Agents; Cattle; Diminazene; Injections, Intramuscular; Male; Protozoan Infections; Protozoan Infections, Animal; Therapeutic Equivalency | 1994 |
Ligand-induced formation of nucleic acid triple helices.
Topics: Circular Dichroism; Diminazene; DNA; Ethidium; Fluorescent Dyes; Indoles; Netropsin; Nucleic Acid Conformation; Poly A; Poly T; RNA; Spectrophotometry; Thermodynamics | 1994 |
Drug cytotoxicity assay for African trypanosomes and Leishmania species.
Topics: Acid Phosphatase; Amphotericin B; Animals; Camptothecin; Diminazene; Drug Evaluation, Preclinical; Leishmania donovani; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1995 |
DNA sequence preferences of several AT-selective minor groove binding ligands.
Topics: Base Composition; Base Sequence; Binding Sites; Bisbenzimidazole; Diminazene; Distamycins; DNA; Ligands; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Structure-Activity Relationship | 1995 |
Disposition of diminazene aceturate (Berenil) in trypanosome-infected pregnant and lactating cows.
Topics: Animals; Animals, Suckling; Cattle; Diminazene; Female; Lactation; Milk; Pregnancy; Pregnancy Complications, Parasitic; Tissue Distribution; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
Berenil [1,3-bis(4'-amidinophenyl)triazene] binding to DNA duplexes and to a RNA duplex: evidence for both intercalative and minor groove binding properties.
Topics: Binding Sites; Calorimetry; Circular Dichroism; Diminazene; DNA; Hot Temperature; Intercalating Agents; Magnetic Resonance Spectroscopy; Models, Chemical; Nucleic Acid Denaturation; RNA, Double-Stranded; Spectrophotometry, Ultraviolet; Trypanocidal Agents; Viscosity | 1995 |
Use of monoclonal antibodies for detecting T brucei brucei infection in splenectomised dogs.
Topics: Animals; Antibodies, Monoclonal; Antigens, Protozoan; Antiprotozoal Agents; Diminazene; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Male; Splenectomy; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1995 |
Novel acridine-triazenes as prototype combilexins: synthesis, DNA binding, and biological activity.
Topics: Acridines; Animals; Antineoplastic Agents; Base Sequence; Cattle; Diminazene; DNA; Drug Design; Humans; Models, Molecular; Molecular Sequence Data; Thymus Gland; Triazenes; Tumor Cells, Cultured | 1995 |
Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in east African Zebu cows exposed to drug-resistant trypanosomes.
Topics: Abortion, Veterinary; Animals; Cattle; Diminazene; Drug Resistance; Ethiopia; Female; Hematocrit; Incidence; Lactation; Pregnancy; Pregnancy Complications, Parasitic; Prevalence; Reproduction; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1995 |
DNA minor groove-binding ligands: a different class of mammalian DNA topoisomerase I inhibitors.
Topics: Animals; Base Sequence; Benzimidazoles; Bisbenzimidazole; Cattle; Diminazene; Distamycins; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Indoles; Intercalating Agents; Kinetics; Ligands; Molecular Sequence Data; Oligodeoxyribonucleotides; Structure-Activity Relationship; Thymus Gland; Topoisomerase I Inhibitors | 1993 |
Interaction of minor-groove-binding diamidine ligands with an asymmetric DNA duplex. NMR and molecular modelling studies.
Topics: Benzamidines; Binding Sites; Computer Simulation; Diminazene; DNA; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1995 |
Antileishmanial activity of berenil and methylglyoxal bis (guanylhydrazone) and its correlation with S-adenosylmethionine decarboxylase and polyamines.
Topics: Adenosylmethionine Decarboxylase; Animals; Antiprotozoal Agents; Diminazene; Dose-Response Relationship, Drug; Kinetics; Leishmania donovani; Mitoguazone; Polyamines; Probability; Time Factors | 1995 |
Suppressor macrophages in Trypanosoma brucei infection: nitric oxide is related to both suppressive activity and lifespan in vivo.
Topics: Animals; Antiprotozoal Agents; Apoptosis; Diminazene; DNA Damage; Female; Immune Tolerance; Immunotherapy, Adoptive; Lymphocyte Activation; Macrophages, Peritoneal; Mice; Mice, Inbred C3H; Nitric Oxide; Spleen; T-Lymphocytes; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
Drug sensitivity screening in vitro of populations of Trypanosoma congolense originating from cattle and tsetse flies at Nguruman, Kenya.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Ethidium; Kenya; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1993 |
Effect of verapamil on antitrypanosomal activity of drugs in mice.
Topics: Animals; Diminazene; Drug Resistance; Drug Synergism; Ethidium; Female; Mice; Microscopy, Fluorescence; Trypanocidal Agents; Trypanosoma brucei brucei; Verapamil | 1993 |
Trypanosoma brucei, T. congolense and T. vivax infections in horses on a farm in Kenya.
Topics: Animals; Diminazene; Disease Outbreaks; Horse Diseases; Horses; Kenya; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African | 1994 |
Berenil complexation with a nucleic acid triple helix.
Topics: Base Sequence; Binding Sites; Circular Dichroism; Diminazene; DNA; Molecular Sequence Data; Nucleic Acid Conformation | 1994 |
Polyamine content and drug sensitivities of different clonal lines of Leishmania infantum promastigotes.
Topics: Animals; Diminazene; Drug Resistance; Eflornithine; Leishmania infantum; Polyamines; Putrescine; Spermidine | 1994 |
Time-dose response of Trypanosoma congolense bloodstream forms to diminazene and isometamidium.
Topics: Animals; Diminazene; Dose-Response Relationship, Drug; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense | 1994 |
Purification of Caenorhabditis elegans DNA topoisomerase I.
Topics: Animals; Caenorhabditis elegans; Camptothecin; Diminazene; DNA Topoisomerases, Type I; Peptide Fragments; Topoisomerase I Inhibitors; Trypanocidal Agents | 1994 |
Time-dose-response of Trypanosoma brucei brucei to diminazene aceturate (Berenil) and in vitro simulation of drug-concentration-time profiles in cattle plasma.
Topics: Animals; Cattle; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Trypanocidal Agents; Trypanosoma brucei brucei | 1993 |
Berenil acts as a poison of eukaryotic topoisomerase II.
Topics: Animals; Binding Sites; Cattle; Diminazene; DNA Replication; DNA Topoisomerases, Type II; DNA, Kinetoplast; DNA, Superhelical; Electrophoresis, Agar Gel; Thymus Gland; Topoisomerase II Inhibitors | 1994 |
Relapse of Trypanosoma congolense infection in goats after diminazene aceturate is not a result of invasion of the central nervous system.
Topics: Animals; Diminazene; Goat Diseases; Goats; Male; Recurrence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1994 |
Combination chemotherapy of drug-resistant Trypanosoma brucei rhodesiense infections in mice using DL-alpha-difluoromethylornithine and standard trypanocides.
Topics: Animals; Arsenicals; Diminazene; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Eflornithine; Female; Mice; Suramin; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 1994 |
Putrescine uptake inhibition by aromatic diamidines in Leishmania infantum promastigotes.
Topics: Amidines; Animals; Diminazene; Indoles; Kinetics; Leishmania infantum; Pentamidine; Putrescine; Stilbamidines | 1994 |
In vivo effect of berenil on rat liver polyamine metabolism.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Animals; Biogenic Polyamines; Diminazene; Liver; Male; Ornithine Decarboxylase; Rats | 1993 |
Berenil recognizes and changes the characteristics of adenine and thymine polynucleotide structures.
Topics: Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Deoxyribonuclease I; Diminazene; Nucleic Acid Conformation; Poly dA-dT; Thermodynamics | 1993 |
Trypanosoma evansi: in vivo and in vitro determination of trypanocide resistance profiles.
Topics: Animals; Arsenicals; Diminazene; Drug Resistance; Phenanthridines; Quinolinium Compounds; Suramin; Trypanocidal Agents; Trypanosoma | 1993 |
A thermodynamic and spectroscopic study on the binding of berenil to poly d(AT) and to poly (dA) x poly (dT).
Topics: Diminazene; Poly dA-dT; Polydeoxyribonucleotides; Spectrophotometry, Ultraviolet; Thermodynamics | 1993 |
The effect of trypanocidal drug treatment on the haematological changes in Trypanosoma brucei brucei infected splenectomised dogs.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Diminazene; Dog Diseases; Dogs; Erythrocyte Count; Erythrocyte Indices; Female; Hematocrit; Hemoglobins; Leukocyte Count; Male; Reticulocytes; Splenectomy; Trypanosoma brucei brucei; Trypanosomiasis, African | 1993 |
Gametocytogenesis induction by Berenil in cultured Plasmodium falciparum.
Topics: Animals; Antiprotozoal Agents; Concanavalin A; Culture Media; Diminazene; Plasmodium falciparum | 1993 |
Effect of Berenil on polyamine metabolism in primary cultured rat hepatocytes.
Topics: Adenosylmethionine Decarboxylase; Animals; Cells, Cultured; Diminazene; Liver; Male; Ornithine Decarboxylase; Putrescine; Rats; Spermidine | 1993 |
Voltammetric behavior of berenil.
Topics: Diminazene; Electrochemistry; Electrodes; Hydrogen-Ion Concentration; Oxidation-Reduction; Polarography; Trypanocidal Agents | 1993 |
Aromatic diamidines are reversible inhibitors of porcine kidney diamine oxidase.
Topics: Acquired Immunodeficiency Syndrome; Amine Oxidase (Copper-Containing); Animals; Benzamidines; Binding Sites; Diminazene; Kidney; Kinetics; Pentamidine; Stilbamidines; Swine | 1993 |
The Bo-RBC-SCID mouse model for evaluating the efficacy of anti-theilerial drugs.
Topics: Aminoquinolines; Animals; Antiprotozoal Agents; Cattle; Diminazene; Drug Evaluation, Preclinical; Erythrocyte Transfusion; Female; Mice; Mice, SCID; Models, Biological; Naphthoquinones; Theileria | 1993 |
NMR and molecular modeling studies of the interaction of berenil and pentamidine with d(CGCAAATTTGCG)2.
Topics: Base Sequence; Binding Sites; Crystallography; Diminazene; DNA; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides; Pentamidine; Trypanocidal Agents | 1993 |
Berenil binding to higher ordered nucleic acid structures: complexation with a DNA and RNA triple helix.
Topics: Base Composition; Calorimetry; Diminazene; DNA; Kinetics; Macromolecular Substances; Nucleic Acid Conformation; Nucleic Acid Denaturation; Poly A-U; Poly dA-dT; RNA; Structure-Activity Relationship; Thermodynamics; Trypanocidal Agents | 1995 |
The chemotherapeutic efficacy of diminazene aceturate and lithium chloride against relapse infection of Trypanosoma brucei brucei in rats.
Topics: Animals; Blood-Brain Barrier; Dexamethasone; Diminazene; Drug Therapy, Combination; Female; Lithium Chloride; Male; Parasitemia; Rats; Rats, Wistar; Recurrence; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
The effect of Trypanosoma brucei brucei infection on rabbit plasma iron and zinc concentrations.
Topics: Acute-Phase Reaction; Animals; Diminazene; Hematocrit; Iron; Leukocyte Count; Male; Rabbits; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Zinc | 1995 |
Kinetoplasts play an important role in the drug responses of Trypanosoma brucei.
Topics: Acriflavine; Animals; Azides; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Ethidium; Female; Light; Mice; Mitochondria; Mitoguazone; Mutation; Parasitemia; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 1995 |
Influence of GC and AT specific DNA minor groove binding drugs on intermolecular triplex formation in the human c-Ki-ras promoter.
Topics: Base Sequence; Binding Sites; Diminazene; Distamycins; DNA; DNA Footprinting; Humans; Ligands; Molecular Sequence Data; Nucleic Acid Conformation; Plicamycin; Promoter Regions, Genetic; Proto-Oncogene Proteins p21(ras) | 1996 |
A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.
Topics: Adenosine; Animals; Arsenicals; Biological Transport, Active; Carrier Proteins; Diminazene; Drug Resistance; Kinetics; Pentamidine; Receptors, Purinergic P2; Trypanocidal Agents; Trypanosoma | 1995 |
Use of electric linear dichroism and competition experiments with intercalating drugs to investigate the mode of binding of Hoechst 33258, berenil and DAPI to GC sequences.
Topics: Base Sequence; Binding, Competitive; Bisbenzimidazole; Diminazene; Indoles; Intercalating Agents; Molecular Sequence Data; Molecular Structure; Poly dA-dT; Polydeoxyribonucleotides; Spectrum Analysis | 1995 |
The effects of hyperosmolar agents lithium chloride and sucrose on the brain concentration of diminazene aceturate in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Diminazene; Female; Lithium Chloride; Male; Permeability; Rats; Rats, Wistar; Sucrose; Tissue Distribution; Trypanocidal Agents; Trypanosomiasis, African | 1995 |
French Guyanan stock of Trypanosoma vivax resistant to diminazene aceturate but sensitive to isometamidium chloride.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Phenanthridines; Trypanocidal Agents; Trypanosoma vivax | 1995 |
The binding mode of drugs to the TAR RNA of HIV-1 studied by electric linear dichroism.
Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Ethidium; HIV Long Terminal Repeat; HIV-1; Humans; Indoles; Intercalating Agents; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Proflavine; RNA, Viral; Spectrum Analysis | 1996 |
Trypanocidal resistance in Trypanosoma evansi in vitro: effects of verapamil, cyproheptidine, desipramine and chlorpromazine alone and in combination with trypanocides.
Topics: Animals; Calcium Channel Blockers; Chlorpromazine; Cyproheptadine; Desipramine; Diminazene; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Melarsoprol; Suramin; Trypanocidal Agents; Trypanosoma; Verapamil | 1996 |
A crystallographic and spectroscopic study of the complex between d(CGCGAATTCGCG)2 and 2,5-bis(4-guanylphenyl)furan, an analogue of berenil. Structural origins of enhanced DNA-binding affinity.
Topics: Amidines; Animals; Antifungal Agents; Base Sequence; Benzamidines; Binding Sites; Diminazene; DNA; Intercalating Agents; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Pneumocystis; Rats; Spectrophotometry; Thermodynamics; Trypanocidal Agents | 1996 |
Resistance to diminazine aceturate by Trypanosoma congolense from cattle in the Zambezi Valley of Zimbabwe.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zimbabwe | 1995 |
Synthesis, characterization, and DNA modification induced by a novel Pt-berenil compound with cytotoxic activity.
Topics: Antineoplastic Agents; Circular Dichroism; Diminazene; DNA Adducts; DNA, Neoplasm; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Nucleic Acid Conformation; Platinum Compounds; Tumor Cells, Cultured | 1996 |
Kinetoplast DNA minicircle binding proteins in a Leishmania Spp: interference of protein DNA interaction by berenil.
Topics: Animals; Antiprotozoal Agents; Base Sequence; Diminazene; DNA-Binding Proteins; DNA, Kinetoplast; Leishmania; Molecular Sequence Data | 1995 |
Effect of tsetse control on trypanosome prevalence in livestock: problems of experimental design and statistical interpretation--a case study in northern Côte d'Ivoire.
Topics: Animal Husbandry; Animals; Cattle; Cote d'Ivoire; Diminazene; Insect Control; Insect Vectors; Sheep; Sheep Diseases; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1996 |
Minor groove binding ligands alter the rotational positioning of DNA fragments on nucleosome core particles.
Topics: Base Composition; Base Sequence; Bisbenzimidazole; Deoxyribonuclease I; Diminazene; Distamycins; DNA Footprinting; DNA, Bacterial; Hydroxyl Radical; Ligands; Molecular Sequence Data; Netropsin; Nucleic Acid Conformation; Nucleosomes; Plasmids | 1996 |
Targeting the minor groove of DNA: crystal structures of two complexes between furan derivatives of berenil and the DNA dodecamer d(CGCGAATTCGCG)2.
Topics: Crystallography, X-Ray; Diminazene; DNA; Furans; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides | 1996 |
Linked lexitropsins and the in vitro inhibition of HIV-1 reverse transcriptase RNA-directed DNA polymerization: a novel induced-fit of 3,5 m-pyridyl bisdistamycin to enzyme-associated template-primer.
Topics: Antiviral Agents; Bisbenzimidazole; Diminazene; Distamycins; DNA Polymerase I; DNA Primers; Electrophoresis, Polyacrylamide Gel; HIV Reverse Transcriptase; Indoles; Kinetics; Models, Molecular; Netropsin; RNA-Directed DNA Polymerase; Templates, Genetic; Thymine Nucleotides | 1996 |
Post-treatment hind-leg paralysis in mice infected with Trypanosoma brucei brucei: a light microscopic study.
Topics: Animals; Brain; Diminazene; Female; Hindlimb; Inflammation; Lymphocytes; Mice; Paralysis; Spinal Cord; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 1997 |
Effect of diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense in Glossina morsitans centralis.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Goats; Insect Vectors; Male; Mice; Parasitemia; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1997 |
The role of the polyamine inhibitor eflornithine in the neuropathogenesis of experimental murine African trypanosomiasis.
Topics: Animals; Brain; Brain Diseases; Diminazene; Eflornithine; Female; Mice; Mice, Inbred Strains; Polyamines; Putrescine; Trypanocidal Agents; Trypanosomiasis, African | 1997 |
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei | 1997 |
Anthraquinone photonucleases: a surprising role for chloride in the sequence-neutral cleavage of DNA and the footprinting of minor groove-bound ligands.
Topics: Anthraquinones; Chlorides; Diminazene; DNA; DNA Damage; DNA Footprinting; Hydrogen; Hydroxyl Radical; Intercalating Agents; Ligands; Netropsin; Photochemistry; Superoxides | 1997 |
Mitochondrial DNA topoisomerase I of Saccharomyces cerevisiae.
Topics: Aminocoumarins; Camptothecin; Coumarins; Diminazene; Disinfectants; DNA Topoisomerases, Type I; Imidazoles; Mitochondria; Saccharomyces cerevisiae; Topoisomerase I Inhibitors | 1997 |
The berenil ligand directs the DNA binding of the cytotoxic drug Pt-berenil.
Topics: Adenosine; Antineoplastic Agents; Binding Sites; Cisplatin; Deoxyribonuclease BamHI; Deoxyribonuclease HindIII; Deoxyribonuclease I; Diminazene; DNA; DNA Footprinting; Enzyme Inhibitors; Guanosine; Intercalating Agents; Magnetic Resonance Spectroscopy; Organoplatinum Compounds | 1997 |
A financial analysis of treatment strategies for Trypanosoma evansi in the Brazilian Pantanal.
Topics: Animals; Brazil; Cattle; Cost-Benefit Analysis; Decision Making; Diminazene; Horse Diseases; Horses; Phenanthridines; Risk Factors; Seasons; Trypanocidal Agents; Trypanosomiasis; Trypanosomiasis, Bovine | 1998 |
The cure of acute Babesiasis perroncitoi in swine.
Topics: Animals; Antiprotozoal Agents; Babesiosis; China; Diminazene; Quinolinium Compounds; Swine; Swine Diseases; Urea | 1997 |
Studies on the comprehensive control of babesiasis in cattle and buffaloes.
Topics: Animals; Antiprotozoal Agents; Arachnid Vectors; Babesiosis; Buffaloes; Cattle; Cattle Diseases; China; Diazinon; Diminazene; Imidocarb; Incidence; Insecticides; Prevalence; Seasons; Tick Control; Tick Infestations; Ticks | 1997 |
Response of a T. b. rhodesiense stock with reduced drug susceptibility in vitro to treatment in mice and cattle.
Topics: Animals; Cattle; Diminazene; DNA, Protozoan; Drug Resistance; Male; Mice; Phenanthridines; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 1998 |
Immunoregulation in experimental murine Trypanosoma congolense infection: anti-IL-10 antibodies reverse trypanosome-mediated suppression of lymphocyte proliferation in vitro and moderately prolong the lifespan of genetically susceptible BALB/c mice.
Topics: Animals; Diminazene; Disease Susceptibility; Female; Interleukin-10; Life Expectancy; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; T-Lymphocytes; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 1998 |
MGBG analogues as potent inhibitors of S-adenosylmethionine decarboxylase of Onchocerca volvulus.
Topics: Adenosylmethionine Decarboxylase; Animals; Cloning, Molecular; Deoxyadenosines; Diminazene; Enzyme Inhibitors; Escherichia coli; Filaricides; Filarioidea; Genetic Vectors; Helminth Proteins; Humans; Mitoguazone; Onchocerca volvulus; Organic Chemicals; Polyamines; Recombinant Proteins | 1998 |
Therapeutic effects of some antihaematozoal drugs against Haemoproteus columbae in domestic pigeons.
Topics: Animals; Animals, Domestic; Antiprotozoal Agents; Bird Diseases; Coccidiosis; Columbidae; Diminazene; Haemosporida; Naphthoquinones; Quinolinium Compounds | 1999 |
Cytokines and antibody responses during Trypanosoma congolense infections in two inbred mouse strains that differ in resistance.
Topics: Animals; Antibodies, Protozoan; Antiprotozoal Agents; Cytokines; Diminazene; Epitopes, B-Lymphocyte; Female; Immunity, Innate; Interferon-gamma; Interleukin-10; Interleukin-4; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Parasitemia; Spleen; Trypanosoma congolense; Trypanosomiasis, African; Variant Surface Glycoproteins, Trypanosoma | 1999 |
Rinderpest vaccination and the incidence and development of trypanosomosis in cattle.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Hematocrit; Incidence; Insect Vectors; Kenya; Male; Neutralization Tests; Rinderpest; Rinderpest virus; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Vaccination; Viral Vaccines | 1999 |
Improvement of cattle productivity through rapid alleviation of African animal trypanosomosis by integrated disease management practices in the agropastoral zone of Yalé, Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Diminazene; Female; Hematocrit; Humans; Insect Control; Insect Vectors; Insecticides; Interviews as Topic; Milk; Nitriles; Pregnancy; Pyrethrins; Seasons; Sentinel Surveillance; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 1999 |
The susceptibility of Djallonké and Djallonké-Sahelian crossbred sheep to Trypanosoma congolense and helminth infection under different diet levels.
Topics: Animal Feed; Animals; Anthelmintics; Antibodies, Protozoan; Antiprotozoal Agents; Crosses, Genetic; Diminazene; Disease Susceptibility; Feces; Female; Fenbendazole; Gambia; Helminthiasis, Animal; Helminths; Hematocrit; Male; Nutritional Status; Parasite Egg Count; Parasitemia; Random Allocation; Sheep; Sheep Diseases; Trypanosoma congolense; Trypanosomiasis, African | 1999 |
Hematology of natural bovine trypanosomosis in the Brazilian Pantanal and Bolivian wetlands.
Topics: Abortion, Veterinary; Anemia, Hypochromic; Anemia, Macrocytic; Animals; Bolivia; Brazil; Cattle; Diarrhea; Diminazene; Erythrocyte Count; Female; Hematocrit; Hemoglobins; Leukocyte Count; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 1999 |
Administration of diminazene aceturate or imidocarb dipropionate for treatment of cytauxzoonosis in cats.
Topics: Animals; Antiprotozoal Agents; Blood; Blood Transfusion; Body Temperature; Cat Diseases; Cats; Diminazene; Erythrocyte Count; Hematocrit; Hematologic Diseases; Heparin; Imidocarb; Injections, Intramuscular; Isotonic Solutions; Leukocyte Count; Male; Piroplasmida; Protozoan Infections; Protozoan Infections, Animal; Urinalysis | 1999 |
Susceptibility of N'Dama cattle to experimental challenge and cross-species superchallenges with bloodstream forms of Trypanosoma congolense and T. vivax.
Topics: Animals; Cattle; Diminazene; Disease Susceptibility; Gambia; Hematocrit; Male; Parasitemia; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Weight Gain | 1999 |
DNA multimode interaction with berenil and pentamidine; double helix stiffening, unbending and bending.
Topics: Animals; Cattle; Diminazene; DNA; DNA, Complementary; Intercalating Agents; Kinetics; Ligands; Models, Theoretical; Nucleic Acid Conformation; Pentamidine; Temperature; Trypanocidal Agents | 1999 |
An analysis of trypanocidal drug use in the Eastern Province of Zambia.
Topics: Age Factors; Animals; Cattle; Cattle Diseases; Diminazene; Drug Utilization; Female; Insect Control; Male; Phenanthridines; Surveys and Questionnaires; Trypanocidal Agents; Trypanosomiasis; Tsetse Flies; Zambia | 2000 |
Determination by capillary zone electrophoresis of berenil, phenamidine, diampron and dibromopropamidine in serum and urine.
Topics: Animals; Benzamidines; Carbanilides; Diminazene; Electrolytes; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Temperature | 2000 |
Defining the drug incorporation properties of PLA-PEG nanoparticles.
Topics: Anesthetics, Local; Calorimetry; Chemical Phenomena; Chemistry, Physical; Diminazene; Drug Compounding; Excipients; Freeze Drying; Lactates; Microspheres; Particle Size; Peptides; Polyethylene Glycols; Procaine; Thermodynamics | 2000 |
Phosphatase-triggered guest release from a cyclodextrin complex.
Topics: Alkaline Phosphatase; Antineoplastic Agents; Binding Sites; Cyclodextrins; Diminazene; Half-Life; Hydrolysis; Indoles; Intercalating Agents; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Mimicry; Phosphorus Compounds; Phosphorylation; Titrimetry | 2000 |
Quinoxaline antibiotics enhance peptide nucleic acid binding to double-stranded DNA.
Topics: Adjuvants, Pharmaceutic; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Binding Sites; Diminazene; DNA; Echinomycin; Electrophoresis, Polyacrylamide Gel; Intercalating Agents; Netropsin; Peptide Nucleic Acids; Plicamycin; Quinoxalines | 2000 |
Multiple-drug resistant Trypanosoma congolense populations in village cattle of Metekel district, north-west Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Ethiopia; Mice; Mice, Inbred BALB C; Parasitemia; Phenanthridines; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2000 |
The use of trypanocides and antibiotics by Maasai pastoralists.
Topics: Animal Husbandry; Animals; Anti-Bacterial Agents; Cattle; Diminazene; Ethidium; Female; Incidence; Kenya; Male; Oxytetracycline; Trypanocidal Agents; Trypanosomiasis, Bovine | 2000 |
Enhanced lipid peroxide levels in the erythrocytes of calves with haemoglobinuria.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Diminazene; Erythrocytes; Hematocrit; Hemoglobins; Hemoglobinuria; Lipid Peroxides; Malondialdehyde; Theileria annulata; Theileriasis | 2001 |
Validation of a polymerase chain reaction assay for monitoring the therapeutic efficacy of diminazene aceturate in trypanosome-infected sheep.
Topics: Animals; Antibodies, Protozoan; Diminazene; Enzyme-Linked Immunosorbent Assay; Polymerase Chain Reaction; Sheep; Sheep Diseases; Trypanocidal Agents; Trypanosomiasis | 2001 |
Cytokines and the acute phase response in post-treatment reactive encephalopathy of Trypanosoma brucei brucei infected mice.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Cytokines; Diminazene; Disease Models, Animal; Encephalitis; Female; Haptoglobins; Mice; Parasitemia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serum Amyloid P-Component; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2001 |
Effect of clindamycin therapy on phagocytic and oxidative activity profiles of spleen mononuclear cells in Babesia rodhaini-infected mice.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Babesia; Babesiosis; Clindamycin; Diminazene; Female; Hematocrit; Macrophages; Mice; Mice, Inbred BALB C; Organ Size; Oxygen; Parasitemia; Phagocytosis; Rodent Diseases; Spleen | 2001 |
Heterogeneous DNA binding modes of berenil.
Topics: Animals; Calorimetry, Differential Scanning; Circular Dichroism; Diminazene; DNA; Models, Molecular; Molecular Structure; Thermodynamics | 2001 |
Concentration-dependent inhibition of sheep erythrocyte ghost plasma membrane Ca2+-ATPase activity by Berenil.
Topics: Animals; Calcium-Transporting ATPases; Diminazene; Dose-Response Relationship, Drug; Erythrocytes; Membrane Proteins; Sheep; Trypanocidal Agents | 2001 |
Drug-resistant Trypanosoma congolense in naturally infected donkeys in north Omo Zone, southern Ethiopia.
Topics: Animals; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Equidae; Ethiopia; Female; Male; Mice; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2001 |
Changes in properties of adenosine transporters in Trypanosoma evansi and modes of selection of resistance to the melaminophenyl arsenical drug, Mel Cy.
Topics: Adenine; Adenosine; Animals; Arsenicals; Biological Transport; Biomarkers; Carrier Proteins; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Inosine; Membrane Transport Proteins; Nucleoside Transport Proteins; Parasitic Sensitivity Tests; Trypanocidal Agents; Trypanosoma | 2001 |
Discriminating small molecule DNA binding modes by single molecule force spectroscopy.
Topics: Bacteriophage lambda; Cisplatin; Cross-Linking Reagents; Diminazene; DNA, Viral; Ethidium; Intercalating Agents; Microscopy, Atomic Force; Nucleic Acid Conformation; Stress, Mechanical | 2002 |
In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga.
Topics: Acanthamoeba; Animals; Antiprotozoal Agents; Benzamidines; Diminazene; Humans; Pentamidine; Polyamines; Pyridines; Robenidine | 2001 |
Effect of strand orientation on the interaction of berenil with DNA triple helices.
Topics: Base Sequence; Chromatography, High Pressure Liquid; Circular Dichroism; Diminazene; DNA; Models, Chemical; Molecular Sequence Data; Oligonucleotides; Potassium Chloride; Protein Binding; Sequence Homology, Nucleic Acid; Temperature; Ultraviolet Rays | 2002 |
Inhibition of DNA replication by berenil in plasmids containing Poly(dA)poly(dT) sequences.
Topics: Diminazene; DNA; DNA Replication; Escherichia coli; Plasmids; Poly A; Poly T; Recombination, Genetic; Thymidine | 2002 |
Determination of affinity, stoichiometry and sequence selectivity of minor groove binder complexes with double-stranded oligodeoxynucleotides by electrospray ionization mass spectrometry.
Topics: Base Sequence; Benzimidazoles; Bisbenzimidazole; Circular Dichroism; Diminazene; DNA; Indoles; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Thermodynamics; Titrimetry | 2002 |
Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda.
Topics: Animals; Cattle; Diminazene; Disease Models, Animal; Drug Resistance; Ethidium; Female; Goat Diseases; Goats; Male; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Uganda | 2002 |
Determination of diminazene aceturate in pharmaceutical formulations by HPLC and identification of related substances by LC/MS.
Topics: Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Liquid; Diminazene; Spectrometry, Mass, Electrospray Ionization | 2002 |
Lipid-drug-conjugate (LDC) nanoparticles as novel carrier system for the hydrophilic antitrypanosomal drug diminazenediaceturate.
Topics: Blood-Brain Barrier; Diminazene; Drug Carriers; Drug Compounding; Drug Stability; Humans; Lipids; Microspheres; Nanotechnology; Particle Size; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Trypanocidal Agents; Trypanosomiasis, African | 2002 |
Electron paramagnetic resonance dynamic signatures of TAR RNA-small molecule complexes provide insight into RNA structure and recognition.
Topics: Acridines; Anti-HIV Agents; Binding, Competitive; Bisbenzimidazole; Diminazene; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Framycetin; Guanidines; HIV Long Terminal Repeat; Indoles; Macromolecular Substances; RNA, Viral; Spin Labels; Structure-Activity Relationship; Thermodynamics | 2002 |
Inhibition of DNA replication by berenil of bacterial plasmids containing poly(dA)-poly(dT) sequences. 2D gel analysis of replicative intermediates.
Topics: Base Sequence; Caffeine; Diminazene; DNA Replication; DNA, Bacterial; Intercalating Agents; Molecular Sequence Data; Plasmids; Poly dA-dT; Restriction Mapping | 2002 |
[Trypanosomiasis and babesiasis in Africa and their treatment with the new preparation berenil].
Topics: Africa; Amidines; Aniline Compounds; Animals; Apicomplexa; Babesiosis; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Dog Diseases; Dogs; Infections; Trypanosomiasis; Trypanosomiasis, African | 1955 |
[Berenil, a new drug for babesiasis of domestic animals].
Topics: Amidines; Aniline Compounds; Animals; Animals, Domestic; Apicomplexa; Babesiosis; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Dog Diseases; Dogs; Infections; Sheep; Sheep Diseases | 1955 |
[Action of berenil in subclinical cases of theileriasis in cattle and buffaloes].
Topics: Amidines; Aniline Compounds; Animals; Buffaloes; Cattle; Cattle Diseases; Coloring Agents; Diminazene; Humans; Protozoan Infections; Theileriasis | 1956 |
[Studies on the action of di-(4-amidophenyl)-triazene-(n-1, 3)-diaceturate (berenil)].
Topics: Amidines; Aniline Compounds; Coloring Agents; Diminazene; Triazenes | 1956 |
Effects of x-rays and trypan blud on reticuloendothelial cells.
Topics: Coloring Agents; Diminazene; Humans; Mononuclear Phagocyte System; X-Rays | 1957 |
The action of berenil on trypanosomes, including strains resistant to antrycide and to stilbamidine.
Topics: Amidines; Aniline Compounds; Animals; Coloring Agents; Diminazene; Quinolinium Compounds; Stilbamidines; Trypanosoma; Trypanosomiasis | 1958 |
An effect of the vital dye trypan red on approach-avoidance conflict.
Topics: Azo Compounds; Coloring Agents; Diminazene; Humans; Learning | 1958 |
[Behavior of interstitial cells (Leydig) of testes of albino rats after trypan bleu vital staining].
Topics: Animals; Diminazene; Humans; Leydig Cells; Male; Rats; Staining and Labeling; Testis | 1958 |
[Mechanism of action of berenil (4,4'-diamidino-diazoaminobenzol) on Trypanosoma congolense].
Topics: Amidines; Aniline Compounds; Animals; Coloring Agents; Diminazene; Trypanosoma congolense; Trypanosomiasis | 1958 |
A strain of Trypanosoma congolense directly resistant to berenil.
Topics: Animals; Antiparasitic Agents; Azo Compounds; Diminazene; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
DRUG-RESISTANCE OF TRYPANOSOMA CONGOLENSE AND OTHER TRYPANOSOMES TO QUINAPYRAMINE, PHENANTHRIDINES, BERENIL AND OTHER COMPOUNDS IN MICE.
Topics: Animals; Antiprotozoal Agents; Diminazene; Mice; Phenanthridines; Quinolines; Quinolinium Compounds; Research; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African | 1963 |
THE APPARENT LOSS OF THE KINETOPLAST OF TRYPANOSOMA EVANSI AFTER TREATMENT OF AN EXPERIMENTALLY INFECTED HORSE WITH BERENIL.
Topics: Amidines; Animals; Blood; Blood Proteins; Cell Nucleus; Diminazene; Erythrocytes; Hemoglobins; Horses; Pharmacology; Rabbits; Rats; Research; Suramin; Triazines; Trypanosoma; Trypanosomiasis | 1964 |
IN VIVO PROPHYLACTIC ACTIVITY OF BERENIL AGAINST TRYPANOSOMES IN MICE.
Topics: Animals; Antiprotozoal Agents; Diminazene; Mice; Pharmacology; Research; Trypanosomiasis | 1965 |
[New clinical experiences on the variable behavior of trypan-red-labelled polyvinylpyrrolidone in the serum and urine of healthy subjects and those with glomerular kidney diseases].
Topics: Azo Compounds; Diminazene; Healthy Volunteers; Kidney Diseases; Kidney Function Tests; Povidone | 1959 |
Berenil in the treatment of Trypanosoma gambiense infection in man.
Topics: Amidines; Aniline Compounds; Animals; Black People; Diminazene; Humans; Trypanosoma brucei gambiense; Trypanosomiasis; Trypanosomiasis, African | 1962 |
The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes.
Topics: Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Diminazene; Enzyme Induction; Hepatocytes; Humans; In Vitro Techniques; Male; Methylcholanthrene; Nitriles; Pentamidine; Phenobarbital; Pyrethrins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Trypanocidal Agents | 2003 |
The effects of diminazene aceturate and ceftriaxone on ram sperm.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Ceftriaxone; Diminazene; Hyaluronoglucosaminidase; Male; Semen; Sheep; Sperm Count; Sperm Motility; Spermatozoa | 2004 |
Changes in adenosine transport associated with melaminophenyl arsenical (Mel CY) resistance in Trypanosoma evansi: down-regulation and affinity changes of the P2 transporter.
Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Down-Regulation; Drug Resistance; Inosine; Kinetics; Nucleoside Transport Proteins; Trypanocidal Agents; Trypanosoma | 2003 |
Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage.
Topics: Animals; Antiprotozoal Agents; Aphidicolin; Blood; Diminazene; DNA Damage; Enzyme Inhibitors; Gene Silencing; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Membrane Glycoproteins; Pentamidine; Protozoan Proteins; RNA Polymerase I; S Phase; Suramin; Transcription, Genetic; Trypanocidal Agents; Trypanosoma brucei brucei; Up-Regulation; Variant Surface Glycoproteins, Trypanosoma | 2004 |
A large-scale trial to evaluate the efficacy of a 1% pour-on formulation of cyfluthrin (Cylence, Bayer) in controlling bovine trypanosomosis in Eastern Zambia.
Topics: Administration, Topical; Animals; Cattle; Diminazene; Hematocrit; Incidence; Insecticides; Nitriles; Pyrethrins; Seasons; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Zambia | 2004 |
The effects of diminazene aceturate on systemic blood pressure in clinically healthy adult dogs.
Topics: Animals; Antiprotozoal Agents; Babesiosis; Blood Pressure; Diminazene; Dog Diseases; Dogs; Female; Heart Rate; Injections, Intramuscular; Male; Time Factors | 2003 |
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in african trypanosomes.
Topics: Adenosine; Animals; Biological Transport, Active; Diminazene; Drug Resistance; Female; Kinetics; Mutation; Nucleoside Transport Proteins; Rats; Rats, Wistar; Saccharomyces cerevisiae; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2004 |
Application of field methods to assess isometamidium resistance of trypanosomes in cattle in western Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance; Ethiopia; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, Bovine | 2004 |
Micronuclei induced by aneugens and clastogens in mononucleate and binucleate cells using the cytokinesis block assay.
Topics: Adult; Aneugens; Aneuploidy; Chromosomes, Human, X; Cytokinesis; Diminazene; Female; Humans; In Vitro Techniques; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitomycin; Mutagens; Polyploidy | 2004 |
Trypanocidal failure suggested by PCR results in cattle field samples.
Topics: Animals; Cattle; Diminazene; Drug Resistance, Microbial; Parasitic Sensitivity Tests; Phenanthridines; Polymerase Chain Reaction; Sensitivity and Specificity; Treatment Failure; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2004 |
Degradation of berenil (diminazene aceturate) in acidic aqueous solution.
Topics: Benzamidines; Buffers; Catalysis; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diminazene; Drug Stability; Gastrointestinal Tract; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Solutions; Trypanocidal Agents | 2004 |
Protective efficacy of isometamidium chloride and diminazene aceturate against natural Trypanosoma brucei, Trypanosoma congolense and Trypanosoma vivax infections in cattle under a suppressed tsetse population in Uganda.
Topics: Animals; Cattle; Diminazene; Female; Insect Control; Male; Phenanthridines; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies; Uganda | 2004 |
Semicarbazide-functionalized Si(111) surfaces for the site-specific immobilization of peptides.
Topics: Diminazene; Microscopy, Atomic Force; Microscopy, Fluorescence; Molecular Structure; Peptides; Silicon; Spectrophotometry; Water | 2005 |
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.
Topics: Age Factors; Animals; Cattle; Diminazene; Ethiopia; Female; Incidence; Insect Control; Insect Vectors; Longitudinal Studies; Male; Models, Biological; Odds Ratio; Prevalence; Recurrence; Risk Factors; Seasons; Sensitivity and Specificity; Sex Factors; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine; Tsetse Flies | 2004 |
Knowledge and attitudes of cattle owners regarding trypanosomosis control in tsetse-infested areas of Uganda.
Topics: Animal Husbandry; Animals; Cattle; Diminazene; Health Knowledge, Attitudes, Practice; Insect Control; Insect Vectors; Insecticides; Phenanthridines; Pilot Projects; Surveys and Questionnaires; Trypanocidal Agents; Trypanosomiasis, Bovine; Tsetse Flies; Uganda | 2004 |
Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenylalanine) copolymer shows potential for formation of a micellar drug carrier.
Topics: Chemical Phenomena; Chemistry, Physical; Delayed-Action Preparations; Diminazene; Drug Carriers; Drug Delivery Systems; Indicators and Reagents; Micelles; Microscopy, Electron, Transmission; Particle Size; Phenylalanine; Polyethylene Glycols; Scattering, Radiation | 2005 |
Acquired resistance to berenil in a cloned isolate of Trypanosoma evansi is associated with upregulation of a novel gene, TeDR40.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Diminazene; Drug Resistance; Genes, Protozoan; Molecular Sequence Data; Protozoan Proteins; RNA, Messenger; Sequence Homology, Amino Acid; Trypanocidal Agents; Trypanosoma; Up-Regulation | 2005 |
Thermodynamic evaluation and modeling of proton and water exchange associated with benzamidine and berenil binding to beta-trypsin.
Topics: Animals; Benzamidines; Calorimetry; Cattle; Diminazene; Hydrogen-Ion Concentration; Models, Chemical; Molecular Structure; Osmotic Pressure; Protein Binding; Protons; Thermodynamics; Trypsin; Trypsin Inhibitors; Water | 2005 |
Diminazene aceturate resistance on the virulence of Trypanosoma brucei for rats.
Topics: Animals; Diminazene; Drug Resistance; Female; Male; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis; Virulence | 2005 |
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.
Topics: Acid Phosphatase; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Berberine Alkaloids; Bisbenzimidazole; Camptothecin; Cell Line; Diminazene; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Luciferases, Firefly; Luminescent Agents; Macrophages; Monocytes; Pentamidine; Quercetin; Topoisomerase I Inhibitors | 2006 |
Quantitative analysis of DNA-porphyrin interactions.
Topics: Biopolymers; Circular Dichroism; Diminazene; DNA; Ligands; Methyl Green; Models, Chemical; Models, Statistical; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Polydeoxyribonucleotides; Polynucleotides; Porphyrins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectrophotometry; Static Electricity; Temperature | 2006 |
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.
Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2006 |
Comparative application of wavelet approaches to absorption and ratio spectra for the simultaneous determination of diminazene aceturate and phenazone in veterinary granules for injection.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Antiprotozoal Agents; Antipyrine; Chemistry, Pharmaceutical; Diminazene; Injections; Pharmaceutical Solutions; Powders; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Veterinary Drugs | 2005 |
Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.
Topics: Animals; Diminazene; Drug Resistance; Humans; Mass Screening; Melarsoprol; Phenanthridines; Recurrence; Suramin; Tanzania; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2006 |
Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.
Topics: Animals; Diminazene; Disease Susceptibility; Goat Diseases; Goats; Male; Nigeria; Parasitemia; Random Allocation; Treatment Outcome; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2006 |
The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.
Topics: Animals; Diminazene; Drug Resistance; Ethidium; Mice; Mozambique; Parasitic Sensitivity Tests; Phenanthridines; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2005 |
Confirmation of diminazene diaceturate in bovine plasma using electrospray liquid chromatography-mass spectrometry.
Topics: Animals; Cattle; Chromatography, Liquid; Diminazene; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Trypanocidal Agents | 2006 |
Trypanosomiasis by Trypanosoma vivax in cattle in the Brazilian semiarid: Description of an outbreak and lesions in the nervous system.
Topics: Abortion, Veterinary; Animals; Antibodies, Protozoan; Brain; Brazil; Cattle; Cattle Diseases; Diminazene; Disease Outbreaks; Female; Nervous System; Pregnancy; Trypanocidal Agents; Trypanosoma vivax; Trypanosomiasis, African | 2007 |
SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Mice; Nucleoside Transport Proteins; Parasitic Sensitivity Tests; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Protozoan Proteins; Time Factors; Trypanocidal Agents; Trypanosoma congolense | 2006 |
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1.
Topics: Antineoplastic Agents; Benzamidines; Diminazene; DNA; DNA, Single-Stranded; Drug Evaluation, Preclinical; Electrochemistry; Humans; Kinetics; Luminescent Measurements; Pentamidine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Thymidine | 2007 |
Occurrence of multiple drug resistance in Trypanosoma brucei rhodesiense isolated from sleeping sickness patients.
Topics: Animals; Diminazene; Drug Resistance, Multiple; Humans; Kenya; Melarsoprol; Mice; Parasitic Sensitivity Tests; Phenanthridines; Random Allocation; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda | 2007 |
Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica.
Topics: Animals; Antiprotozoal Agents; Babesia; Brucea; Diminazene; Indonesia; Inhibitory Concentration 50; Molecular Structure; Plants, Medicinal; Quassins | 2007 |
Acute phase response in mice experimentally infected with Trypanosoma congolense: a molecular gauge of parasite-host interaction.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Anemia; Animals; Diminazene; Disease Models, Animal; Female; Haptoglobins; Hematocrit; Host-Parasite Interactions; Mice; Random Allocation; Serum Amyloid P-Component; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2008 |
Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs.
Topics: Animals; Blood Cell Count; Body Temperature; Diminazene; Dog Diseases; Dogs; Enzymes; Female; Hemoglobins; Male; Pentamidine; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 2008 |
Prevalence of bovine trypanosomosis and trypanocidal drug sensitivity studies on Trypanosoma congolense in Wolyta and Dawero zones of southern Ethiopia.
Topics: Animals; Biological Assay; Cattle; Cross-Sectional Studies; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Drug Resistance, Multiple; Ethiopia; Hematocrit; Longitudinal Studies; Mice; Parasitic Sensitivity Tests; Phenanthridines; Prevalence; Treatment Outcome; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, Bovine | 2008 |
Microarray analysis of the in vivo sequence preferences of a minor groove binding drug.
Topics: Binding Sites; Cells, Cultured; Diminazene; Gene Expression; Intercalating Agents; Microarray Analysis; Nucleic Acid Conformation; RNA, Messenger; Sequence Analysis, DNA | 2008 |
Enhancement of hydrophilic drug loading and release characteristics through micellization with new carboxymethyldextran-PEG block copolymers of tunable charge density.
Topics: Chemistry, Pharmaceutical; Dextrans; Diminazene; Drug Carriers; Drug Stability; Drug Storage; Freeze Drying; Hydrogen-Ion Concentration; Micelles; Polyethylene Glycols; Polymers; Salinity; Sodium Chloride; Trehalose | 2008 |
Comparative efficacy of diminazene diaceturate and diminazene aceturate for the treatment of babesiosis in horses.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; Female; Horse Diseases; Horses; Male | 2008 |
Five-fold increase in Trypanosoma congolense isolates resistant to diminazene aceturate over a seven-year period in Eastern Zambia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Protozoan; Dose-Response Relationship, Drug; Drug Resistance; Mice; Mice, Inbred Strains; Polymorphism, Restriction Fragment Length; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Zambia | 2008 |
Immunospecific immunoglobulins and IL-10 as markers for Trypanosoma brucei rhodesiense late stage disease in experimentally infected vervet monkeys.
Topics: Animals; Antigens, Protozoan; Biomarkers; Brain; Chlorocebus aethiops; Diminazene; Female; Immunoglobulin G; Immunoglobulin M; Interleukin-10; Male; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2009 |
Structure and inhibition of human diamine oxidase.
Topics: Amine Oxidase (Copper-Containing); Animals; Binding Sites; Calcium; Copper; Crystallography, X-Ray; Dimerization; Diminazene; Drosophila; Humans; Kinetics; Metallothionein; Models, Molecular; Pentamidine; Promoter Regions, Genetic; Protein Conformation; Substrate Specificity; X-Ray Diffraction | 2009 |
The effects of hairpin loops on ligand-DNA interactions.
Topics: Base Sequence; Diminazene; DNA; Indoles; Ligands; Netropsin; Surface Plasmon Resonance | 2009 |
Multiple genetic mechanisms lead to loss of functional TbAT1 expression in drug-resistant trypanosomes.
Topics: 3' Untranslated Regions; Diminazene; DNA, Protozoan; Drug Resistance; Membrane Transport Proteins; Open Reading Frames; Protozoan Proteins; Trypanocidal Agents; Trypanosoma brucei brucei | 2010 |
Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Cell Division; Clindamycin; Diminazene; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Doxycycline; Drug Resistance; Erythrocytes; Metronidazole; Pentamidine | 2010 |
Structural binding evidence of the trypanocidal drugs berenil and pentacarinate active principles to a serine protease model.
Topics: Animals; Calorimetry; Cattle; Crystallography, X-Ray; Diminazene; Models, Molecular; Pentamidine; Thermodynamics; Trypanocidal Agents; Trypsin; Trypsin Inhibitors | 2010 |
Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; Dog Diseases; Dogs; Doxycycline; Drug Therapy, Combination; Enrofloxacin; Female; Fluoroquinolones; Male; Metronidazole; Retrospective Studies; Taiwan; Tick-Borne Diseases | 2010 |
Babesia canis and Babesia rossi co-infection in an untraveled Nigerian dog.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; DNA, Protozoan; Dog Diseases; Dogs; Female; Nigeria; Polymerase Chain Reaction; Sequence Analysis, DNA | 2010 |
Polyamine pathway contributes to the pathogenesis of Parkinson disease.
Topics: Acetyltransferases; alpha-Synuclein; Animals; Brain Stem; Diminazene; Genetic Variation; Humans; Magnetic Resonance Imaging; Mice; Mice, Transgenic; Parkinson Disease; Pemoline; Polyamines | 2010 |
Reduced transcript levels of the heat shock protein 70 gene in diminazene aceturate-resistant Babesia gibsoni variants under low concentrations of diminazene aceturate.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Resistance; HSP70 Heat-Shock Proteins; Transcription, Genetic | 2010 |
Specific berenil-DNA interactions: an approach for separation of plasmid isoforms by pseudo-affinity chromatography.
Topics: Ammonium Sulfate; Chromatography, Affinity; Diminazene; DNA; Kinetics; Ligands; Plasmids; Sepharose; Sodium Chloride | 2011 |
Influence of trypanocidal therapy on the haematology of vervet monkeys experimentally infected with Trypanosoma brucei rhodesiense.
Topics: Anemia, Macrocytic; Animals; Blood Platelets; Cerebrospinal Fluid; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Female; Hematology; Leukocytes; Male; Melarsoprol; Thrombocytopenia; Trypanosoma brucei rhodesiense; Trypanosomiasis, African | 2011 |
Diminazene aceturate associated with sodium selenite and vitamin E in the treatment of Trypanosoma evansi infection in rats.
Topics: Animals; Antioxidants; Diminazene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Lipid Peroxidation; Polymerase Chain Reaction; Rats; Rats, Wistar; Sodium Selenite; Thiobarbituric Acid Reactive Substances; Trypanocidal Agents; Trypanosoma; Trypanosomiasis; Vitamin E | 2011 |
Experimental infection with Rangelia vitalii in dogs: acute phase, parasitemia, biological cycle, clinical-pathological aspects and treatment.
Topics: Acute Disease; Animals; Antiprotozoal Agents; Apicomplexa; Case-Control Studies; Diminazene; Dog Diseases; Dogs; Endothelium, Vascular; Erythrocytes; Female; Hematocrit; Leukocytes; Male; Parasitemia; Protozoan Infections, Animal | 2011 |
Genital lesions in male red fronted gazelles (Gazella rufifrons) experimentally infected with Trypanosoma brucei and the effect of melarsamine hydrochloride (Cymelarsan®) and diminazene aceturate (Berenil®) in its treatment.
Topics: Animals; Antelopes; Arsenicals; Body Temperature; Diminazene; Genital Diseases, Male; Hematocrit; Histocytochemistry; Male; Parasitemia; Semen; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
Highly debilitating natural Trypanosoma vivax infections in Brazilian calves: epidemiology, pathology, and probable transplacental transmission.
Topics: Animals; Antiprotozoal Agents; Brazil; Cattle; Cattle Diseases; Diminazene; Infectious Disease Transmission, Vertical; Parasitemia; Prevalence; Severity of Illness Index; Survival Analysis; Trypanosoma vivax; Trypanosomiasis, African | 2012 |
CBFB and MYH11 in inv(16)(p13q22) of acute myeloid leukemia displaying close spatial proximity in interphase nuclei of human hematopoietic stem cells.
Topics: 2-Aminopurine; Aphidicolin; Cell Nucleus; Cells, Cultured; Chromosome Fragile Sites; Core Binding Factor beta Subunit; Diminazene; Fibroblasts; Hematopoietic Stem Cells; Humans; In Situ Hybridization, Fluorescence; Interphase; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Mesenchymal Stem Cells; Microscopy, Confocal; Myosin Heavy Chains; Translocation, Genetic | 2011 |
Cerebroprotection by angiotensin-(1-7) in endothelin-1-induced ischaemic stroke.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Endothelin-1; Enzyme Activation; Infarction, Middle Cerebral Artery; Male; Nitric Oxide Synthase Type II; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Stroke | 2011 |
The effects of combination of methanolic leaf extract of Azadirachta indica and diminazene diaceturate in the treatment of experimental Trypanosoma brucei brucei infection in rats.
Topics: Animals; Azadirachta; Diminazene; Drug Resistance; Drug Therapy, Combination; Female; Male; Parasitemia; Phytotherapy; Plant Extracts; Plant Leaves; Rats; Trypanosoma brucei brucei; Trypanosomiasis, African | 2011 |
Validation of an HPLC method for the simultaneous determination of diminazene diaceturate and phenazone in injectable veterinary granules and bulk powders.
Topics: Antipyrine; Chromatography, High Pressure Liquid; Diminazene; Injections; Limit of Detection; Powders; Veterinary Drugs | 2012 |
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.
Topics: Africa South of the Sahara; Alleles; Animals; Antiprotozoal Agents; Diminazene; Disease Models, Animal; DNA, Protozoan; Drug Resistance; Mice; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Selection, Genetic; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso.
Topics: Animals; Burkina Faso; Cattle; Cross-Sectional Studies; Diminazene; Longitudinal Studies; Phenanthridines; Trypanosoma vivax; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2012 |
Serial haematology results in transfused and non-transfused dogs naturally infected with Babesia rossi.
Topics: Animals; Antiprotozoal Agents; Babesiosis; Blood Cell Count; Blood Transfusion; Diminazene; Dog Diseases; Dogs; Female; Longitudinal Studies; Male; Prospective Studies; Thrombocytopenia | 2011 |
Energetics of ligand binding to the DNA minor groove.
Topics: Binding Sites; Diminazene; DNA; Ligands; Organic Chemicals; Thermodynamics | 2012 |
Involvement of mitochondrial genes of Babesia gibsoni in resistance to diminazene aceturate.
Topics: Amino Acid Sequence; Antiprotozoal Agents; Babesia; Base Sequence; Culture Techniques; Diminazene; DNA Primers; Drug Resistance; Genes, Mitochondrial; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA | 2012 |
Investigation of the antitrypanosomal activity of Buchholzia coriacea seed extract against a field strain of Trypanosoma congolense.
Topics: Administration, Oral; Animals; Capparaceae; Diminazene; Dose-Response Relationship, Drug; Female; Hematocrit; Male; Methanol; Mice; Parasitemia; Phytotherapy; Plant Extracts; Seeds; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2011 |
Detection of multiple drug-resistant Trypanosoma congolense populations in village cattle of south-east Mali.
Topics: Animals; Antiprotozoal Agents; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance, Multiple; Mali; Phenanthridines; Rural Population; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Tsetse Flies | 2012 |
Purification of plasmid DNA from clarified and non-clarified Escherichia coli lysates by berenil pseudo-affinity chromatography.
Topics: Chromatography, Affinity; Chromatography, High Pressure Liquid; Diminazene; DNA; Escherichia coli; Plasmids; Real-Time Polymerase Chain Reaction; Sodium Chloride | 2012 |
Evaluation of in vitro and in vivo inhibitory effects of fusidic acid on Babesia and Theileria parasites.
Topics: Animals; Antiparasitic Agents; Babesia; Babesiosis; Cells, Cultured; Diminazene; Drug Synergism; Female; Fusidic Acid; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Theileria; Theileriasis; Time Factors | 2013 |
Biochemical and morphological changes in Trypanosoma brucei brucei-infected rats treated with homidium chloride and diminazene aceturate.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Diminazene; Ethidium; Male; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2012 |
Analysis of energy generation and glycolysis pathway in diminazene aceturate-resistant Babesia gibsoni isolate in vitro.
Topics: Adenosine Triphosphate; Antiprotozoal Agents; Babesia; Diminazene; Energy Metabolism; Glucose; Glycolysis; L-Lactate Dehydrogenase; Lactic Acid; Pyruvate Kinase; Pyruvic Acid | 2012 |
The prevalence of bovine trypanosomes in parts of Benue state, north-central Nigeria.
Topics: Animals; Cattle; Diminazene; Hematocrit; Nigeria; Prevalence; Trypanosoma vivax; Trypanosomiasis, Bovine; Tsetse Flies | 2012 |
Diminazene aceturate (Berenil) modulates the host cellular and inflammatory responses to Trypanosoma congolense infection.
Topics: Animals; Cytokines; Diminazene; Enzyme-Linked Immunosorbent Assay; Female; Forkhead Transcription Factors; Immunity, Cellular; Inflammation; Interleukin-2 Receptor alpha Subunit; Kupffer Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Spleen; T-Lymphocytes; Trypanosoma congolense; Trypanosomiasis, African | 2012 |
Blocking Babesia bovis vaccine reactions of dairy cattle in milk.
Topics: Animals; Babesia bovis; Babesiosis; Cattle; Cattle Diseases; Diminazene; Female; Fluorescent Antibody Technique, Indirect; Immunization; Milk; Protozoan Vaccines; Treatment Outcome; Vaccination; Vaccines, Attenuated | 2012 |
Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.
Topics: Animals; Cell Migration Assays; Diminazene; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Hypertension, Pulmonary; Male; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Stem Cells; Trypanocidal Agents | 2013 |
Hematologic and bone marrow changes in dogs experimentally infected with Rangelia vitalii.
Topics: Anemia, Hemolytic; Animals; Antiprotozoal Agents; Babesia; Babesiosis; Bone Marrow; Diminazene; Dog Diseases; Dogs; Erythroid Cells; Female; Hyperplasia | 2013 |
Angiotensin-converting enzyme 2 activation for treatment of pulmonary hypertension.
Topics: Animals; Diminazene; Hypertension, Pulmonary; Male; Trypanocidal Agents | 2013 |
A validated and stability indicating HPLC method for analysis of diminazene aceturate and antipyrine combination in a ready injectable solution.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Chromatography, High Pressure Liquid; Diminazene; Drug Stability; Injections; Limit of Detection; Solutions; Trypanocidal Agents | 2013 |
Trypanocidal activity of the essential oils in their conventional and nanoemulsion forms: in vitro tests.
Topics: Anacardiaceae; Animals; Biological Assay; Culture Media; Diminazene; Dose-Response Relationship, Drug; Emulsions; Hydrogen-Ion Concentration; Meliaceae; Mice; Nanostructures; Oils, Volatile; Osmolar Concentration; Plant Extracts; Trypanocidal Agents; Trypanosoma | 2013 |
Diminazene aceturate improves autonomic modulation in pulmonary hypertension.
Topics: Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Arterial Pressure; Autonomic Nervous System; Diminazene; Heart Rate; Hypertension, Pulmonary; Male; Monocrotaline; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2013 |
Seroprevalence of Trypanosoma evansi infection in water buffaloes from the mountainous region of North Vietnam and effectiveness of trypanocidal drug treatment.
Topics: Age Factors; Agglutination Tests; Animals; Antiprotozoal Agents; Buffaloes; Cattle; Communicable Disease Control; Diminazene; Seroepidemiologic Studies; Treatment Outcome; Trypanosoma; Trypanosomiasis, Bovine; Vietnam | 2013 |
Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Caspase 3; Cell Count; Diminazene; Disease Models, Animal; Enzyme Activation; Fluorescent Antibody Technique, Indirect; Glaucoma; Immunoenzyme Techniques; Intraocular Pressure; Male; Nerve Fibers; Ophthalmic Solutions; Optic Nerve; Peptide Fragments; Peptidyl-Dipeptidase A; Radionuclide Imaging; Rats; Rats, Wistar; Renin-Angiotensin System; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Tonometry, Ocular | 2013 |
Biochemical responses of Anticarsia gemmatalis (Lepidoptera: Noctuidae) in soybean cultivars sprayed with the protease inhibitor berenil.
Topics: Animals; Diminazene; Gastrointestinal Tract; Glycine max; Insect Control; Insect Proteins; Lipoxygenase; Moths; Peptide Hydrolases; Plant Diseases; Plant Proteins; Protease Inhibitors | 2013 |
Enzymatic response of the eucalypt defoliator Thyrinteina arnobia (Stoll) (Lepidoptera: Geometridae) to a bis-benzamidine proteinase Inhibitor. i.
Topics: Animals; Benzamidines; Digestive System; Diminazene; Dose-Response Relationship, Drug; Eucalyptus; Larva; Lepidoptera; Plant Leaves; Serine Proteinase Inhibitors | 2012 |
Diminazene aceturate enhances angiotensin-converting enzyme 2 activity and attenuates ischemia-induced cardiac pathophysiology.
Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diminazene; Heart; Hemodynamics; Macrophages; Myocardial Infarction; Myocardial Ischemia; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Stem Cells | 2013 |
Failure of efficacy and adverse events associated with dose-intense diminazene diaceturate treatment of chronic Cytauxzoon felis infection in five cats.
Topics: Animals; Antiprotozoal Agents; Carrier State; Cat Diseases; Cats; Chronic Disease; Diminazene; Dose-Response Relationship, Drug; Female; Male; Parasitic Diseases, Animal; Treatment Failure | 2014 |
Inhibitory effect of allicin on the growth of Babesia and Theileria equi parasites.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Diminazene; Disulfides; Drug Synergism; Drug Therapy, Combination; Erythrocytes; Female; Inhibitory Concentration 50; Mice; Mice, Inbred BALB C; Parasitemia; Sulfinic Acids; Theileria | 2014 |
Diminazene aceturate (Berenil) modulates LPS induced pro-inflammatory cytokine production by inhibiting phosphorylation of MAPKs and STAT proteins.
Topics: Animals; Cytokines; Diminazene; Down-Regulation; Female; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphorylation; STAT Transcription Factors; Suppressor of Cytokine Signaling Proteins; Toll-Like Receptors; Trypanocidal Agents | 2014 |
Neurological trypanosomiasis in quinapyramine sulfate-treated horses--a breach of the blood-brain barrier?
Topics: Animals; Blood-Brain Barrier; Central Nervous System Infections; Diminazene; Disease Outbreaks; Enzyme-Linked Immunosorbent Assay; Horse Diseases; Horses; India; Quinolinium Compounds; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2014 |
Negative pseudo-affinity chromatography for plasmid DNA purification using berenil as ligand.
Topics: Chromatography, Affinity; Diminazene; DNA, Circular; Particle Size; Plasmids; Sepharose | 2014 |
Flavonoid mixture ameliorates increase in erythrocyte osmotic fragility and malondialdehyde concentration induced by Trypanosoma brucei brucei-infection in Wistar rats.
Topics: Animals; Diminazene; Diosmin; Erythrocytes; Male; Malondialdehyde; Osmotic Fragility; Parasitemia; Random Allocation; Rats; Rats, Wistar; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Kenyan purple tea anthocyanins and coenzyme-Q10 ameliorate post treatment reactive encephalopathy associated with cerebral human African trypanosomiasis in murine model.
Topics: Animals; Anthocyanins; Body Weight; Central Nervous System Diseases; Diminazene; Female; Hematocrit; Humans; Mice; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Ubiquinone | 2014 |
Liposomes produced by reverse phase evaporation: in vitro and in vivo efficacy of diminazene aceturate against Trypanosoma evansi.
Topics: Animals; Chemistry, Pharmaceutical; Diminazene; Liposomes; Male; Nanotechnology; Rats, Wistar; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2014 |
Inhibition of spermidine/spermine N1-acetyltransferase activity: a new therapeutic concept in rheumatoid arthritis.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Aged; Animals; Arthritis, Rheumatoid; Cells, Cultured; Diminazene; DNA Methylation; Drug Design; Enzyme Inhibitors; Female; Fibroblasts; Humans; Male; Mice; Mice, SCID; Middle Aged; Promoter Regions, Genetic; RNA, Small Interfering; S-Adenosylmethionine; Synovial Membrane; Transcription Factors | 2014 |
Antitrypanosomal activity of aloin and its derivatives against Trypanosoma congolense field isolate.
Topics: Animals; Anthraquinones; Diminazene; Dose-Response Relationship, Drug; Emodin; Female; Mice; Molecular Structure; Random Allocation; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Inference on arthropod demographic parameters: computational advances using R.
Topics: Animals; Coleoptera; Diminazene; Female; Life Tables; Male; Models, Biological; Moths; Software; Temperature | 2014 |
Evaluation of in vivo antitrypanosomal activity of crude extracts of Artemisia abyssinica against aTrypanosoma congolense isolate.
Topics: Animals; Artemisia; Diminazene; Female; Humans; Male; Mice; Parasitemia; Phytotherapy; Plant Components, Aerial; Plant Extracts; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2014 |
Activation of angiotensin-converting enzyme 2 improves cardiac electrical changes in ventricular repolarization in streptozotocin-induced hyperglycaemic rats.
Topics: Action Potentials; Angiotensin-Converting Enzyme 2; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diminazene; Enzyme Activation; Enzyme Activators; Heart Conduction System; Heart Rate; Heart Ventricles; Hyperglycemia; Male; Peptidyl-Dipeptidase A; Rats, Wistar; Streptozocin; Time Factors | 2014 |
Angiotensin-converting enzyme 2 (ACE2) activator diminazene aceturate ameliorates endotoxin-induced uveitis in mice.
Topics: Angiotensin-Converting Enzyme 2; Animals; Anterior Eye Segment; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Follow-Up Studies; Intercalating Agents; Mice; Mice, Inbred BALB C; Ophthalmic Solutions; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Uveitis | 2014 |
Evaluation of a fluorescence-based method for antibabesial drug screening.
Topics: Antiprotozoal Agents; Babesia bovis; Benzothiazoles; Diamines; Diminazene; Fluorescence; Fluorescent Dyes; High-Throughput Screening Assays; Inhibitory Concentration 50; Limonins; Organic Chemicals; Parasitic Sensitivity Tests; Quinolines; Signal-To-Noise Ratio; Spectrometry, Fluorescence | 2014 |
Effect of diminazene aceturate, levamisole and vitamin C combination therapy in rats experimentally infected with Trypanosoma brucei brucei.
Topics: Animals; Ascorbic Acid; Body Temperature; Body Weight; Diminazene; Drug Therapy, Combination; Hemoglobins; Leukocyte Count; Levamisole; Male; Parasite Load; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2014 |
Diminazene or berenil, a classic duplex minor groove binder, binds to G-quadruplexes with low nanomolar dissociation constants and the amidine groups are also critical for G-quadruplex binding.
Topics: Amidines; Circular Dichroism; Diminazene; DNA; G-Quadruplexes; Ligands; Mass Spectrometry; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Nucleic Acid Conformation; Structure-Activity Relationship; Thermodynamics | 2014 |
Diminazene aceturate liposomes: morphometric and biochemical liver, kidney, and spleen of rats infected with Trypanosoma evansi.
Topics: Animals; Biomarkers; Diminazene; Disease Models, Animal; Kidney; Kidney Function Tests; Liposomes; Liver; Liver Function Tests; Male; Rats, Wistar; Spleen; Time Factors; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2014 |
Angiotensin-converting enzyme 2 decreases formation and severity of angiotensin II-induced abdominal aortic aneurysms.
Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Aortic Aneurysm, Abdominal; Diminazene; Disease Models, Animal; Enzyme Activation; Female; Humans; Hypercholesterolemia; Leukocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Peptidyl-Dipeptidase A; Receptors, LDL; Renin-Angiotensin System; RNA, Messenger | 2014 |
Unveiling the effects of berenil, a DNA-binding drug, on Trypanosoma cruzi: implications for kDNA ultrastructure and replication.
Topics: Cell Proliferation; Cell Survival; Chagas Disease; Diminazene; DNA Replication; Membrane Potential, Mitochondrial; Oxygen; Reactive Oxygen Species; Trypanocidal Agents; Trypanosoma cruzi | 2015 |
Improvements on restricted insecticide application protocol for control of Human and Animal African Trypanosomiasis in eastern Uganda.
Topics: Albendazole; Animals; Cattle; Cattle Diseases; Diminazene; Female; Humans; Insect Control; Insecticides; Male; Population Density; Trypanosomiasis, African; Uganda | 2014 |
Diminazene protects corpus cavernosum against hypercholesterolemia-induced injury.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Diminazene; Down-Regulation; Erectile Dysfunction; Hypercholesterolemia; Male; Mice; Mice, Knockout; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Penile Erection; Penis; Peptide Fragments; Peptidyl-Dipeptidase A; Reactive Oxygen Species | 2015 |
Effects of aqueous extracts of Acacia albida stem bark on Wistar albino rats infected with Trypanosoma evansi.
Topics: Acacia; Alanine Transaminase; Animals; Aspartate Aminotransferases; Diminazene; Kidney; Liver; Parasitemia; Plant Bark; Plant Extracts; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2015 |
Effect of the treatment with Achyrocline satureioides (free and nanocapsules essential oil) and diminazene aceturate on hematological and biochemical parameters in rats infected by Trypanosoma evansi.
Topics: Achyrocline; Animals; Biomarkers; Blood Chemical Analysis; Diminazene; Dogs; Female; Hematologic Tests; Kidney; Liver; Nanocapsules; Oils, Volatile; Parasitemia; Plant Oils; Rats; Rats, Wistar; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2015 |
Down-sizing of neuronal network activity and density of presynaptic terminals by pathological acidosis are efficiently prevented by Diminazene Aceturate.
Topics: Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acidosis; Animals; Axons; Brain; Diminazene; Encephalomyelitis, Autoimmune, Experimental; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mice; Myelin Sheath; Neurons; Presynaptic Terminals; Synaptic Potentials | 2015 |
Angiotensin converting enzyme 2 activator (DIZE) modulates metabolic profiles in mice, decreasing lipogenesis.
Topics: Adipose Tissue; Angiotensin-Converting Enzyme 2; Animals; Body Weight; Diminazene; Enzyme Inhibitors; Humans; Lipogenesis; Male; Mice; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins p21(ras); Transcriptome | 2015 |
PCR and microsatellite analysis of diminazene aceturate resistance of bovine trypanosomes correlated to knowledge, attitude and practice of livestock keepers in South-Western Ethiopia.
Topics: Agriculture; Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Health Knowledge, Attitudes, Practice; Livestock; Longitudinal Studies; Microsatellite Repeats; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prevalence; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2015 |
Short-term treatment with diminazene aceturate ameliorates the reduction in kidney ACE2 activity in rats with subtotal nephrectomy.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diminazene; Female; Gene Expression Regulation, Enzymologic; Kidney; Kidney Cortex; Kidney Medulla; Nephrectomy; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 2015 |
In vivo experimental drug resistance study in Trypanosoma vivax isolates from tsetse infested and non-tsetse infested areas of Northwest Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Communicable Diseases; Diminazene; Drug Resistance; Ethiopia; Insect Vectors; Male; Parasitemia; Phenanthridines; Trypanocidal Agents; Trypanosoma congolense; Trypanosoma vivax; Trypanosomiasis, African; Tsetse Flies | 2015 |
Topical administration of diminazene aceturate decreases inflammation in endotoxin-induced uveitis.
Topics: Administration, Ophthalmic; Angiotensin-Converting Enzyme 2; Animals; Anti-Inflammatory Agents; Aqueous Humor; Cyclooxygenase 2; Dexamethasone; Diminazene; Female; Gene Expression; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Nitric Oxide Synthase Type II; Ophthalmic Solutions; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Uvea; Uveitis | 2015 |
Activation of the Neuroprotective Angiotensin-Converting Enzyme 2 in Rat Ischemic Stroke.
Topics: ADAM Proteins; ADAM17 Protein; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Corpus Striatum; Diminazene; Disease Models, Animal; Endothelin-1; Enzyme Activation; Imidazoles; Infarction, Middle Cerebral Artery; Infusions, Intraventricular; Leucine; Male; Neuroprotective Agents; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Renin-Angiotensin System; RNA, Messenger | 2015 |
The redox status of human breast cancer cell lines (MCF-7 and MDA-MB231) treated with novel dinuclear berenil-platinum(II) complexes.
Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Diminazene; DNA Methylation; Female; Humans; Organoplatinum Compounds; Oxidation-Reduction; Phospholipids; Picolines; Reactive Oxygen Species | 2014 |
Curative drug treatment of trypanosomosis leads to the restoration of B-cell lymphopoiesis and splenic B-cell compartments.
Topics: Animals; B-Lymphocyte Subsets; Bone Marrow; Diminazene; Female; Lymphopoiesis; Mice; Mice, Inbred C57BL; Spleen; Suramin; Trypanocidal Agents; Trypanosomiasis; Trypanosomiasis, African | 2015 |
Ocular Inserts for Sustained Release of the Angiotensin-Converting Enzyme 2 Activator, Diminazene Aceturate, to Treat Glaucoma in Rats.
Topics: Administration, Ophthalmic; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Calorimetry, Differential Scanning; Chitosan; Delayed-Action Preparations; Diminazene; Drug Evaluation, Preclinical; Enzyme Activation; Eye Proteins; Glaucoma; Hyaluronic Acid; Intraocular Pressure; Male; Microscopy, Electron, Scanning; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Tissue Distribution | 2015 |
Glycosaminoglycans are potential pharmacological targets for classic DNA minor groove binder drugs berenil and pentamidine.
Topics: Antiprotozoal Agents; Chondroitin Sulfates; Circular Dichroism; Diminazene; DNA; Glycosaminoglycans; Pentamidine; Spectrophotometry, Ultraviolet | 2015 |
ACE2/Ang-(1-7)/Mas axis stimulates vascular repair-relevant functions of CD34+ cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Antigens, CD34; Cell Adhesion; Cell Movement; Cell Proliferation; Diminazene; Humans; Leukocytes, Mononuclear; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents; Wound Healing; Xanthones | 2015 |
Anti-hypertensive Effects of Diminazene Aceturate: An Angiotensin- Converting Enzyme 2 Activator in Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Diminazene; Heart Rate; Hypertension, Renovascular; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2016 |
Fluorescence-Based Automated Screening Assay for the Study of the pH-Sensitive Channel ASIC1a.
Topics: Acid Sensing Ion Channels; Animals; Automation, Laboratory; Cations, Monovalent; Cell Line; Cerebral Cortex; CHO Cells; Cricetulus; Diminazene; Fluorescent Dyes; High-Throughput Screening Assays; Hydrogen-Ion Concentration; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Peptides; Primary Cell Culture; Pyrans; Pyridinium Compounds; Sodium; Spider Venoms; Styrenes; Transgenes; Voltage-Sensitive Dye Imaging | 2016 |
In vitro and in vivo action of terpinen-4-ol, γ-terpinene, and α-terpinene against Trypanosoma evansi.
Topics: Animals; Cyclohexane Monoterpenes; Diminazene; Dogs; Dose-Response Relationship, Drug; Female; Mice; Monoterpenes; Rats; Terpenes; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2016 |
Intrarenal alterations of the angiotensin-converting enzyme type 2/angiotensin 1-7 complex of the renin-angiotensin system do not alter the course of malignant hypertension in Cyp1a1-Ren-2 transgenic rats.
Topics: Albuminuria; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Body Weight; Cytochrome P-450 CYP1A1; Diminazene; Enzyme Activators; Gene Expression Regulation; Hypertension, Malignant; Kidney; Mice; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Rats; Rats, Transgenic; Renin; Renin-Angiotensin System; Sodium | 2016 |
Drug quality analysis through high performance liquid chromatography of isometamidium chloride hydrochloride and diminazene diaceturate purchased from official and unofficial sources in Northern Togo.
Topics: Chromatography, High Pressure Liquid; Diminazene; Pharmacies; Phenanthridines; Quality Control; Togo; Trypanocidal Agents | 2016 |
Zoonotic trypanosomes in South East Asia: Attempts to control Trypanosoma lewisi using veterinary drugs.
Topics: Animals; Arsenicals; Diminazene; Female; Humans; Mice; Parasitemia; Phenanthridines; Quinolinium Compounds; Rats; Rats, Wistar; Triazines; Trypanocidal Agents; Trypanosoma lewisi; Trypanosomiasis; Veterinary Drugs; Zoonoses | 2016 |
Dual-channel optical sensing platform for detection of diminazene aceturate based on thioglycolic acid-wrapped cadmium telluride/cadmium sulfide quantum dots.
Topics: Animals; Antiprotozoal Agents; Cadmium Compounds; Diminazene; Food Contamination; Limit of Detection; Milk; Quantum Dots; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Sulfides; Tellurium; Thioglycolates | 2016 |
New Trypanosoma evansi Type B Isolates from Ethiopian Dromedary Camels.
Topics: Animals; Arsenicals; Camelus; Diminazene; DNA, Kinetoplast; DNA, Protozoan; Ethiopia; Genotype; Mice; Phenanthridines; Phenotype; Phylogeny; Polymerase Chain Reaction; Proton-Translocating ATPases; Suramin; Triazines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2016 |
Nerolidol nanospheres increases its trypanocidal efficacy against Trypanosoma evansi: New approach against diminazene aceturate resistance and toxicity.
Topics: Administration, Oral; Adult; Animals; Cryopreservation; Diminazene; Dogs; Drug Resistance; Female; Humans; Hydrogen-Ion Concentration; Leukocytes, Mononuclear; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanospheres; Parasitemia; Particle Size; Rats; Sesquiterpenes; Trypanocidal Agents; Trypanosoma; Trypanosomiasis; Young Adult | 2016 |
Cardioprotective effects of diminazene aceturate in pressure-overloaded rat hearts.
Topics: Animals; Cardiotonic Agents; Diminazene; Heart; Hypertrophy, Left Ventricular; In Vitro Techniques; Male; Rats; Rats, Wistar | 2016 |
Diminazene aceturate, an angiotensin-converting enzyme II activator, prevents gastric mucosal damage in mice: Role of the angiotensin-(1-7)/Mas receptor axis.
Topics: Acetic Acid; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Ethanol; Female; Gastric Mucosa; Male; Mice; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Stomach Ulcer | 2016 |
Activation of angiotensin-converting enzyme 2 (ACE2) attenuates allergic airway inflammation in rat asthma model.
Topics: Angiotensin-Converting Enzyme 2; Animals; Anti-Asthmatic Agents; Asthma; Bronchoalveolar Lavage Fluid; Diminazene; Disease Models, Animal; Glutathione; I-kappa B Proteins; Interleukin-1beta; Interleukin-4; Leukocyte Count; Lung; Male; Malondialdehyde; Myocardium; NF-kappa B; Nitric Oxide; Ovalbumin; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Rats, Wistar | 2016 |
Association of exercise training and angiotensin-converting enzyme 2 activator improves baroreflex sensitivity of spontaneously hypertensive rats.
Topics: Angiotensin-Converting Enzyme 2; Animals; Baroreflex; Blood Pressure; Diminazene; Heart Rate; Hypertension; Male; Peptidyl-Dipeptidase A; Physical Conditioning, Animal; Rats; Rats, Inbred SHR; Signal Transduction | 2016 |
Diminazene Aceturate Improves Cardiac Fibrosis and Diastolic Dysfunction in Rats with Kidney Disease.
Topics: Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Diminazene; Female; Fibrosis; Hypertension; Hypertrophy, Left Ventricular; Kidney Diseases; Myocardium; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley | 2016 |
Novel trypanocide from an extract of Pleurotus sajor-caju against Trypanosoma congolense.
Topics: Animals; Biomarkers; Body Weight; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Mice, Inbred BALB C; Parasitemia; Pleurotus; Time Factors; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
IgM, lgG and IL-6 profiles in the Trypanosoma brucei brucei monkey model of human African trypanosomiasis.
Topics: Animals; Antigens, Protozoan; Chlorocebus aethiops; Diminazene; Disease Models, Animal; Disease Progression; Enzyme-Linked Immunosorbent Assay; Immunoglobulin G; Immunoglobulin M; Interleukin-6; Trypanosoma brucei brucei; Trypanosomiasis, African | 2017 |
Trypanosomiasis challenge estimation using the diminazene aceturate (Berenil) index in Zebu in Gabon.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Female; Gabon; Longitudinal Studies; Rain; Seasons; Tropical Climate; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Effects of dihydroorotate dehydrogenase (DHODH) inhibitors on the growth of Theileria equi and Babesia caballi in vitro.
Topics: Amino Acid Sequence; Animals; Antiprotozoal Agents; Atovaquone; Babesia; Babesiosis; Biphenyl Compounds; Computational Biology; Dihydroorotate Dehydrogenase; Diminazene; Enzyme Inhibitors; Horse Diseases; Horses; Inhibitory Concentration 50; Isoxazoles; Leflunomide; Mice; Molecular Weight; Oxidoreductases Acting on CH-CH Group Donors; Phylogeny; Plasmodium berghei; Pyrimidines; Theileria; Theileriasis | 2017 |
Cattle breeding, trypanosomosis prevalence and drug resistance in Northern Togo.
Topics: Animals; Breeding; Cattle; Cattle Diseases; Communicable Disease Control; Cross-Sectional Studies; Diminazene; Drug Resistance; Phenanthridines; Prevalence; Togo; Treatment Failure; Trypanocidal Agents; Trypanosoma; Trypanosoma congolense; Trypanosomiasis; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2017 |
Ultrafast Dynamics of a Triazene: Excited-State Pathways and the Impact of Binding to the Minor Groove of DNA and Further Biomolecular Systems.
Topics: Binding Sites; Diminazene; DNA; G-Quadruplexes; Molecular Structure; Spectrometry, Fluorescence; Triazenes; Trypsin | 2017 |
An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate.
Topics: Adenosine Triphosphate; Animals; Cell Survival; Diminazene; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Luciferases; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African | 2017 |
Evaluation of the inhibitory effect of N-acetyl-L-cysteine on Babesia and Theileria parasites.
Topics: Acetylcysteine; Animals; Antiprotozoal Agents; Babesia; Babesia bovis; Cattle; Diminazene; Drug Synergism; Erythrocytes; Horses; Inhibitory Concentration 50; Spectrometry, Fluorescence; Theileria | 2017 |
FIRST REPORT OF TRYPANOSOMA EVANSI INFECTION (SURRA) IN A PUMA (FELIS CONCOLOR) OF LAHORE ZOO, PAKISTAN.
Topics: Animals; Animals, Zoo; Antiprotozoal Agents; Diminazene; Fatal Outcome; Male; Puma; Trypanosoma; Trypanosomiasis | 2017 |
Adaptation and evaluation of an ELISA for Trypanosoma evansi infection (surra) in elephants and its application to a serological survey in Thailand.
Topics: Acclimatization; Animals; Animals, Domestic; Animals, Wild; Antibodies, Protozoan; Antigens, Protozoan; Buffaloes; Cattle; Diminazene; Disease Reservoirs; Elephants; Enzyme-Linked Immunosorbent Assay; Protozoan Infections, Animal; Seroepidemiologic Studies; Thailand; Trypanosoma; Trypanosomiasis | 2018 |
Piloting a livestock identification and traceability system in the northern Tanzania-Narok-Nairobi trade route.
Topics: Abattoirs; Animal Identification Systems; Animals; Anti-Bacterial Agents; Cattle; Chromatography, High Pressure Liquid; Commerce; Diminazene; Drug Residues; Food Safety; Kenya; Livestock; Meat; Pilot Projects; Red Meat; Tanzania; Tetracycline | 2018 |
Performance and consistency of a fluorescence-based high-throughput screening assay for use in Babesia drug screening in mice.
Topics: Anemia; Animals; Antiprotozoal Agents; Babesia; Benzothiazoles; Diamines; Diminazene; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Fluorescence; Hematocrit; High-Throughput Screening Assays; Leukocytes; Mice, Inbred BALB C; Naphthyridines; Nucleic Acids; Organ Specificity; Organic Chemicals; Parasites; Quinolines; Reproducibility of Results | 2017 |
[Simultaneous determination of diminazene aceturate and isometamidium chloride residues in cattle tissues by high performance liquid chromatography with solid-phase extraction].
Topics: Animals; Cattle; Chromatography, High Pressure Liquid; Diminazene; Drug Residues; Food Contamination; Phenanthridines; Red Meat; Solid Phase Extraction | 2017 |
Chemotherapeutic efficacies of a clofazimine and diminazene aceturate combination against piroplasm parasites and their AT-rich DNA-binding activity on Babesia bovis.
Topics: Animals; Babesia bovis; Clofazimine; Diminazene; DNA, Protozoan; Dose-Response Relationship, Drug; Drug Interactions; Female; GC Rich Sequence; Mice; Mice, Inbred BALB C | 2017 |
Intracellular diminazene aceturate content and adenosine incorporation in diminazene aceturate-resistant Babesia gibsoni isolate in vitro.
Topics: Adenosine; Animals; Babesia; Babesiosis; Blood Glucose; Chromatography, High Pressure Liquid; Diminazene; Dog Diseases; Dogs; Drug Resistance; Erythrocyte Count; Erythrocytes; Hypoxanthine; Male; Parasitemia; Potassium; Sodium | 2017 |
Diminazene aceturate alleviated lipopolysaccharide/D-galactosamine-induced fulminant hepatitis in mice.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Aspartate Aminotransferases; Caspases; Chemical and Drug Induced Liver Injury; Diminazene; Galactosamine; Hepatitis; Interleukin-6; Lipopolysaccharides; Liver; Liver Failure, Acute; Male; Mice; Mice, Inbred BALB C; Tumor Necrosis Factor-alpha | 2018 |
Aberrant use and poor quality of trypanocides: a risk for drug resistance in south western Ethiopia.
Topics: Animal Husbandry; Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Humans; Phenanthridines; Surveys and Questionnaires; Trypanocidal Agents; Trypanosomiasis | 2018 |
Coupling corticotropin-releasing-hormone and angiotensin converting enzyme 2 dampens stress responsiveness in male mice.
Topics: Adrenocorticotropic Hormone; Angiotensin-Converting Enzyme 2; Animals; Anxiety; Corticotropin-Releasing Hormone; Diminazene; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Hormones; Hypothalamo-Hypophyseal System; Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Peptidyl-Dipeptidase A; Pituitary Gland; Pituitary-Adrenal System; Pro-Opiomelanocortin; RNA, Messenger; Stress, Psychological | 2018 |
Effects of Trypanosoma brucei brucei infection and diminazene aceturate administration on the blood pressure, heart rate, and temperature of Wistar albino rats.
Topics: Animals; Blood Pressure; Body Temperature; Diminazene; Heart Rate; Male; Rats; Rats, Wistar; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African | 2018 |
Isothermal microcalorimetry - A quantitative method to monitor Trypanosoma congolense growth and growth inhibition by trypanocidal drugs in real time.
Topics: Animals; Antiprotozoal Agents; Axenic Culture; Calorimetry; Cattle; Computer Systems; Diminazene; Drug Discovery; Drug Resistance; Models, Theoretical; Phenanthridines; Temperature; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, Bovine | 2018 |
[ACE2 agonist DIZE alleviates lung injury induced by limb ischemia-reperfusion in mice].
Topics: Acute Lung Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Hindlimb; Male; Mice; Mice, Inbred ICR; Mice, Transgenic; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Reperfusion Injury | 2018 |
The small molecule drug diminazene aceturate inhibits liver injury and biliary fibrosis in mice.
Topics: Angiotensin-Converting Enzyme 2; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Line; Cytokines; Diminazene; Hepatic Stellate Cells; Humans; Kupffer Cells; Liver; Liver Cirrhosis, Experimental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Peptidyl-Dipeptidase A; Reactive Oxygen Species; Renin-Angiotensin System; Treatment Outcome | 2018 |
ACE2 activator diminazene aceturate reduces adiposity but preserves lean mass in young and old rats.
Topics: Adiposity; Age Factors; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Gene Expression; Male; Obesity; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Inbred F344; Renin-Angiotensin System | 2018 |
The ACE 2 activator diminazene aceturate (DIZE) improves left ventricular diastolic dysfunction following myocardial infarction in rats.
Topics: Angiotensin-Converting Enzyme 2; Animals; Cardiomegaly; Collagen; Diastole; Diminazene; Enzyme Activators; Hemodynamics; Male; Myocardial Infarction; Myocytes, Cardiac; Peptidyl-Dipeptidase A; Rats, Wistar; Ventricular Dysfunction; Ventricular Function | 2018 |
Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B.
Topics: Animals; Arsenicals; Diminazene; Disease Models, Animal; Ethiopia; Female; Injections; Mice; Phenanthridines; Recurrence; Treatment Outcome; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2018 |
Molecular investigation of "Candidatus Mycoplasma haemobos" in goats and sheep in central China.
Topics: Animals; Anthelmintics; Cattle; China; Diminazene; Goat Diseases; Goats; Mycoplasma; Mycoplasma Infections; Polymerase Chain Reaction; Praziquantel; Prevalence; RNA, Ribosomal, 16S; Sheep; Sheep Diseases | 2019 |
Drug quality analysis of isometamidium chloride hydrochloride and diminazene diaceturate used for the treatment of African animal trypanosomosis in West Africa.
Topics: Africa, Western; Animals; Chromatography, High Pressure Liquid; Diminazene; Livestock; Phenanthridines; Quality Control; Trypanocidal Agents; Trypanosomiasis, African | 2018 |
How rational drug use reduces trypanosome infections in cattle in chemo-resistance hot-spot villages of northern Togo.
Topics: Albendazole; Animals; Antimicrobial Stewardship; Cattle; Diminazene; Drug Resistance; Insecticides; Male; Phenanthridines; Ticks; Togo; Trypanocidal Agents; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
Diminazene aceturate (Berenil) downregulates Trypanosoma congolense-induced proinflammatory cytokine production by altering phosphorylation of MAPK and STAT proteins.
Topics: Animals; Cattle; Cell Line, Transformed; Cytokines; Diminazene; Female; Humans; Inflammation Mediators; Macrophages; Mice; Mice, Inbred C57BL; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2019 |
Sustaining Efforts of Controlling Zoonotic Sleeping Sickness in Uganda Using Trypanocidal Treatment and Spray of Cattle with Deltamethrin.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Humans; Insect Vectors; Insecticides; Nitriles; Pyrethrins; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Tsetse Flies; Uganda; Zoonoses | 2019 |
Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Babesia; Babesiosis; Benzoquinones; Diminazene; Disease Models, Animal; Female; Inhibitory Concentration 50; Mice; Phytochemicals; Theileria; Theileriasis | 2019 |
Spermine protects alpha-synuclein expressing dopaminergic neurons from manganese-induced degeneration.
Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Cell Line; Cell Survival; Diminazene; Dopaminergic Neurons; Humans; Manganese; Nerve Degeneration; Neuroprotective Agents; Spermine | 2019 |
Concurrent neprilysin inhibition and renin-angiotensin system modulations prevented diabetic nephropathy.
Topics: Angiotensin-Converting Enzyme 2; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Diminazene; Fibrosis; Inflammation; Kidney; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renin-Angiotensin System; Streptozocin; Telmisartan; Thiorphan | 2019 |
Development of unstable resistance to diminazene aceturate in Babesia bovis.
Topics: Animals; Antiprotozoal Agents; Babesia bovis; Babesiosis; Cattle; Diminazene; Drug Resistance; Erythrocytes; Inhibitory Concentration 50 | 2019 |
Is the cardioprotective effect of the ACE2 activator diminazene aceturate more potent than the ACE inhibitor enalapril on acute myocardial infarction in rats?
Topics: Acute Disease; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiotonic Agents; Diminazene; Enalapril; Enzyme Activation; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Myocardial Infarction; Peptidyl-Dipeptidase A; Rats; Rats, Wistar | 2019 |
Beneficial Effects of the Angiotensin-Converting Enzyme 2 Activator Dize in Renovascular Hypertension.
Topics: Acetylglucosaminidase; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Cytokines; Diminazene; Enzyme Activators; Hypertension, Renovascular; Inflammation; Kidney; Male; Nitric Oxide; Peptide Fragments; Peptidyl-Dipeptidase A; Peroxidase; Rats, Wistar; Renin-Angiotensin System | 2019 |
Suspected resistance of Trypanosoma species to diminazene aceturate on a cattle farm in Nigeria.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; DNA, Intergenic; Drug Resistance; Farms; Nigeria; Polymerase Chain Reaction; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African; Trypanosomiasis, Bovine | 2019 |
In vitro anti-trypanosomal effects of selected phenolic acids on Trypanosoma brucei.
Topics: Animals; Cell Proliferation; Cell Survival; Deferoxamine; Diminazene; Drug Resistance; Gallic Acid; Humans; Hydroxybenzoates; Iron; Mitochondrial Membranes; Trypanocidal Agents; Trypanosoma; Trypanosoma brucei brucei; Trypanosomiasis, African | 2019 |
Trypanocidal drug resistance: A threat to animal health and production in Gidami district of Kellem Wollega Zone, Oromia Regional State, Western Ethiopia.
Topics: Animals; Cattle; Cattle Diseases; Diminazene; Drug Resistance; Ethiopia; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis | 2019 |
Clinical and therapeutic aspects of an outbreak of canine trypanosomiasis.
Topics: Animals; Brazil; Diminazene; Disease Outbreaks; Dog Diseases; Dogs; Female; Male; Phenanthridines; Polymerase Chain Reaction; Quinolinium Compounds; Trypanosomiasis | 2019 |
In silico analysis of heparin and chondroitin sulfate binding mechanisms of the antiprotozoal drug berenil and pentamidine.
Topics: Antiprotozoal Agents; Chondroitin Sulfates; Computer Simulation; Diminazene; Heparin; Hydrogen Bonding; Molecular Conformation; Molecular Dynamics Simulation; Pentamidine; Quantum Theory; Thermodynamics | 2019 |
Angiotensin-converting enzyme 2 attenuates inflammatory response and oxidative stress in hyperoxic lung injury by regulating NF-κB and Nrf2 pathways.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Bronchoalveolar Lavage Fluid; Diminazene; Hyperoxia; Imidazoles; Leucine; Lung Injury; Male; Mice; Mice, Inbred BALB C; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A | 2019 |
Simultaneous inhibition of neprilysin and activation of ACE2 prevented diabetic cardiomyopathy.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Diminazene; Drug Therapy, Combination; Enzyme Activation; Male; Neprilysin; Peptidyl-Dipeptidase A; Rats, Wistar; Streptozocin; Thiorphan | 2019 |
Stimulation of the ACE2/Ang-(1-7)/Mas axis in hypertensive pregnant rats attenuates cardiovascular dysfunction in adult male offspring.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Blood Pressure; Cardiovascular Diseases; Diminazene; Enzyme Activators; Female; Heart; Hypertension, Pregnancy-Induced; Kidney; Male; Myocardial Contraction; Peptide Fragments; Peptidyl-Dipeptidase A; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Ventricular Function, Left | 2019 |
Diminazene aceturate (DIZE) has cellular and in vivo antiarrhythmic effects.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diminazene; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Patch-Clamp Techniques; Rats; Rats, Wistar | 2020 |
ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloidogenic Proteins; Angiotensin-Converting Enzyme 2; Animals; Cognitive Dysfunction; Diminazene; Disease Models, Animal; Mice; Mice, Transgenic; Proto-Oncogene Mas | 2020 |
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Formaldehyde; Humans; Injections, Spinal; Male; Mice; Microglia; Neurons; Nociception; p38 Mitogen-Activated Protein Kinases; Pain; Peptide Fragments; Peptidyl-Dipeptidase A; Phosphorylation; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Spinal Cord | 2020 |
Safety and efficacy of hydroxyurea and eflornithine against most blood parasites Babesia and Theileria.
Topics: Animals; Antineoplastic Agents; Antiprotozoal Agents; Atovaquone; Babesia; Cell Survival; Clofazimine; Diminazene; Dogs; Eflornithine; Foreskin; Humans; Hydroxyurea; Male; Mice; NIH 3T3 Cells; Theileria | 2020 |
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Airway Obstruction; Animals; Animals, Newborn; Bicarbonates; Bronchi; Bronchoalveolar Lavage Fluid; Chlorides; Cystic Fibrosis; Diminazene; Disease Models, Animal; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; Male; Mucin 5AC; Mucin-5B; Mucociliary Clearance; Mucus; Respiratory Mucosa; Swine; Trachea | 2020 |
Treatment Efficiency of Combination Therapy With Diminazene Aceturate and Quinapyramine Sulfate in a Horse With Dourine.
Topics: Animals; Diminazene; Dourine; Horse Diseases; Horses; Male; Mongolia; Quinolinium Compounds; Sulfates | 2020 |
Diminazene aceturate extenuate the renal deleterious consequences of angiotensin-II induced by γ-irradiation through boosting ACE2 signaling cascade.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Gamma Rays; Glutathione; Male; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Signal Transduction; Superoxide Dismutase | 2020 |
Molecular identification of diminazene aceturate-resistant strains of Trypanosoma congolense in naturally infected domestic animals of Yoko in the centre region of Cameroon.
Topics: Animals; Cameroon; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Drug Resistance; Sheep; Sheep Diseases; Sheep, Domestic; Trypanocidal Agents; Trypanosoma congolense; Trypanosomiasis, African | 2020 |
Azithromycin and Diminazene Aceturate Combination Therapy in Experimental Multidrug-resistant Trypanosoma brucei brucei Infection in Albino Rats.
Topics: Animals; Azithromycin; Diminazene; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Rats; Trypanocidal Agents; Trypanosoma brucei brucei | 2020 |
Effects of renal ischemia injury on brain in diabetic and non-diabetic rats: Role of angiotensin II type 2 receptor and angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Animals; Brain; Diabetes Mellitus, Experimental; Diminazene; Hyperglycemia; Imidazoles; Kidney Diseases; Kidney Tubules; Male; Malondialdehyde; Nitrites; Rats, Wistar; Receptor, Angiotensin, Type 2; Reperfusion Injury; Sulfonamides; Thiophenes | 2020 |
Evaluation of the Anticancer Activities of Novel Transition Metal Complexes with Berenil and Nitroimidazole.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Cisplatin; Coordination Complexes; Diminazene; DNA; DNA Topoisomerases, Type II; Female; Gold; Humans; Membrane Potential, Mitochondrial; Mitochondria; Nitroimidazoles; Organometallic Compounds; Palladium; Platinum; Transition Elements; Xenograft Model Antitumor Assays; Zebrafish | 2020 |
Relaxation Dynamics of the Triazene Compound Berenil in DNA-Minor-Groove Confinement after Photoexcitation.
Topics: Diminazene; DNA; Molecular Dynamics Simulation; Photochemical Processes; Quantum Theory | 2020 |
Acute hypotensive effect of diminazene aceturate in spontaneously hypertensive rats: role of NO and Mas receptor.
Topics: Animals; Blood Pressure; Diminazene; Hypertension; Male; Nitric Oxide; Rats | 2020 |
Could DIZE be the answer to COVID-19?
Topics: Angiotensins; Betacoronavirus; Coronavirus Infections; COVID-19; Diminazene; Humans; Pandemics; Peptidyl-Dipeptidase A; Pneumonia, Viral; SARS-CoV-2 | 2020 |
Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study.
Topics: Angiotensin I; Animals; Cell Line; Chagas Cardiomyopathy; Chagas Disease; Diminazene; Dose-Response Relationship, Drug; Male; Mice; Mice, Inbred BALB C; Myocarditis; Myocytes, Cardiac; Myositis; Peptide Fragments; Rats; Renin-Angiotensin System; Trypanocidal Agents | 2020 |
ACE2 activator diminazene aceturate ameliorates Alzheimer's disease-like neuropathology and rescues cognitive impairment in SAMP8 mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Brain Chemistry; Cognitive Dysfunction; Cytokines; Diminazene; Infusions, Parenteral; Male; Maze Learning; Mice; Mice, Neurologic Mutants; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; tau Proteins | 2020 |
Angiotensin-converting enzyme 2 activator, DIZE in the basolateral amygdala attenuates the tachycardic response to acute stress by modulating glutamatergic tone.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Basolateral Nuclear Complex; Diminazene; Glutamic Acid; Heart Rate; Neurons; Peptide Fragments; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tachycardia | 2020 |
Ameliorative effect of AT2R and ACE2 activation on ischemic renal injury associated cardiac and hepatic dysfunction.
Topics: Acute Kidney Injury; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diminazene; Imidazoles; Ischemia; Kidney; Liver; Male; Myocardium; Oxidative Stress; Peptide Fragments; Peroxidase; Rats, Wistar; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes | 2020 |
Occurrence of Trypanosoma spp. and piroplasm infections of horses at Obollo-Afor southeastern Nigeria and resistance profiles of trypanosomes to isometamidium and diminazene salts.
Topics: Animals; Babesiosis; Cross-Sectional Studies; Diminazene; Drug Resistance; Horse Diseases; Horses; Mice; Mice, Inbred BALB C; Nigeria; Phenanthridines; Rats; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis | 2020 |
The beneficial effects of angiotensin-converting enzyme II (ACE2) activator in pulmonary hypertension secondary to left ventricular dysfunction.
Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activators; Humans; Hypertension, Pulmonary; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Ventricular Dysfunction, Left | 2020 |
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model.
Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence | 2020 |
ACE2 activator diminazene aceturate exerts renoprotective effects in gentamicin-induced acute renal injury in rats.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Body Weight; Cytokines; Diminazene; Enzyme Activators; Gentamicins; Inflammation; Kidney; Male; Protective Agents; Rats, Wistar; Renin-Angiotensin System | 2020 |
Reduced expression levels of heat shock protein 90 in a diminazene aceturate-resistant Babesia gibsoni isolate.
Topics: Animals; Antiprotozoal Agents; Babesia; Blotting, Western; Diminazene; Dogs; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Fluorescent Antibody Technique, Indirect; HSP90 Heat-Shock Proteins; Immunoblotting; Potassium; Rabbits; Real-Time Polymerase Chain Reaction | 2021 |
Evaluation of the inhibitory effects of drugs on the growth of Babesia gibsoni using relative quantification real-time PCR.
Topics: Animals; Antiprotozoal Agents; Artesunate; Babesia; Diminazene; Drug Resistance; Erythrocytes; Parasitemia; Parasitic Sensitivity Tests; Real-Time Polymerase Chain Reaction; RNA, Ribosomal, 18S | 2020 |
Cytotoxicity and anti-inflammatory effect of a novel diminazene aceturate derivative in bovine mammary epithelial cells.
Topics: Animals; Anti-Inflammatory Agents; Cattle; Diminazene; Epithelial Cells; Female; Inflammation; Mammary Glands, Animal; MAP Kinase Signaling System; NF-kappa B; Phosphorylation | 2021 |
Diminazene Aceturate Stabilizes Atherosclerotic Plaque and Attenuates Hepatic Steatosis in apoE-Knockout Mice by Influencing Macrophages Polarization and Taurine Biosynthesis.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Apolipoproteins E; Atherosclerosis; Diet, High-Fat; Diminazene; Disease Models, Animal; Fatty Liver; Female; Gene Expression Regulation; Humans; Liver; Macrophage Activation; Macrophages; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Peptide Fragments; Plaque, Atherosclerotic; Taurine; THP-1 Cells | 2021 |
In vitro screening of novel anti-Babesia gibsoni drugs from natural products.
Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Biological Products; Diminazene; Dog Diseases; Dogs; Drug Evaluation, Preclinical; Inhibitory Concentration 50 | 2021 |
Inhibition of endoplasmic reticulum stress combined with activation of angiotensin-converting enzyme 2: novel approach for the prevention of endothelial dysfunction in type 1 diabetic rats.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diminazene; Drug Therapy, Combination; Endoplasmic Reticulum Stress; Endothelium, Vascular; Male; Oxidative Stress; Rats, Wistar; Streptozocin; Taurochenodeoxycholic Acid | 2022 |
Compounds from the Medicines for Malaria Venture Box Inhibit In Vitro Growth of
Topics: Animals; Antiprotozoal Agents; Atovaquone; Babesia; Babesiosis; Blood-Borne Pathogens; Diminazene; Humans; Imidocarb; Malaria; Plants, Medicinal | 2021 |
Assessment of α-Cypermethrin Pour-On Application and Diminazene Aceturate for Treating Trypanosome-Related Diseases Caused by Tsetse Flies on Cattle in Mô, Togo.
Topics: Animals; Cattle; Cattle Diseases; Cross-Sectional Studies; Diminazene; Heteroptera; Pyrethrins; Togo; Trypanosoma; Trypanosomiasis, African; Tsetse Flies | 2022 |
Challenges with the proposed ACE2 activation mechanism of diminazene aceturate.
Topics: Angiotensin-Converting Enzyme 2; Diminazene; Renin-Angiotensin System | 2022 |
Treatment of Cutaneous Balamuthia mandrillaris Infection With Diminazene Aceturate: A Report of 4 Cases.
Topics: Amebiasis; Balamuthia mandrillaris; Cellulitis; Diminazene; Humans | 2022 |
Angiotensin-Converting Enzyme 2 Activation Mitigates Behavioral Deficits and Neuroinflammatory Burden in 6-OHDA Induced Experimental Models of Parkinson's Disease.
Topics: Angiotensin I; Angiotensin-Converting Enzyme 2; Animals; Diminazene; Mice; Models, Theoretical; Oxidopamine; Parkinson Disease; Peptide Fragments; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Rats; Receptors, G-Protein-Coupled; Signal Transduction | 2022 |
Ascorbic acid co-administration with a low dose of diminazene aceturate inhibits the in vitro growth of Theileria equi, and the in vivo growth of Babesia microti.
Topics: Animals; Ascorbic Acid; Babesia; Babesia microti; Babesiosis; Cattle; Diminazene; Horse Diseases; Horses; Mice; Theileria; Theileriasis | 2022 |
Diminazene aceturate mitigates cardiomyopathy by interfering with renin-angiotensin system in a septic rat model.
Topics: Angiotensin-Converting Enzyme 2; Animals; Cardiomyopathies; Diminazene; Rats; Rats, Wistar; Renin-Angiotensin System; Sepsis; Tumor Necrosis Factor-alpha | 2022 |
Mitigation of Multi-Organ Radiation Injury with ACE2 Agonist Diminazene Aceturate.
Topics: Angiotensin-Converting Enzyme 2; Animals; Diminazene; Peptidyl-Dipeptidase A; Radiation Injuries; Rats; Transforming Growth Factor beta | 2022 |
Antiviral potential of diminazene aceturate against SARS-CoV-2 proteases using computational and in vitro approaches.
Topics: Angiotensin-Converting Enzyme 2; Antiparasitic Agents; Antiviral Agents; COVID-19 Drug Treatment; Diminazene; Humans; Molecular Docking Simulation; Peptide Hydrolases; Peptidyl-Dipeptidase A; Protein S; SARS-CoV-2 | 2022 |
African trypanosome infection patterns in cattle in a farm setting in Southern Ghana.
Topics: Animals; Cattle; Diminazene; Drug Resistance; Farms; Female; Ghana; Humans; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |
Variation of sensitivity of Trypanosoma evansi isolates from Isiolo and Marsabit counties of Kenya to locally available trypanocidal drugs.
Topics: Animals; Camelus; Chlorides; Diminazene; Drug Resistance; Kenya; Mice; Phenanthridines; Trypanocidal Agents; Trypanosoma; Trypanosomiasis, African | 2023 |