Page last updated: 2024-08-24

diminazene aceturate and pentamidine

diminazene aceturate has been researched along with pentamidine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (22.50)	18.7374
1990's	11 (27.50)	18.2507
2000's	9 (22.50)	29.6817
2010's	10 (25.00)	24.3611
2020's	1 (2.50)	2.80

Authors

Authors	Studies
Barrett, MP; Brun, R; Dardonville, C; Kaiser, M; Tanious, F; Wilson, WD	1
Buchynskyy, A; Buckner, FS; Creason, SA; Duster, NA; Gelb, MH; Gillespie, JR; Hulverson, MA; McQueen, J; Ranade, RM	1
Bacchi, CJ; Braillard, S; Chatelain, E; Denny, WA; Gaukel, E; Launay, D; Maes, L; Marshall, AJ; Mowbray, CE; Thompson, AM; Wring, SA; Yarlett, N	1
Ang, CW; Avery, VM; Blaskovich, MAT; Butler, MS; Cooper, MA; Debnath, A; Hahn, HJ; Jarrad, AM; Jones, AJ; Karoli, T; Pelingon, R; Sykes, ML; Tan, L; West, NP; Woods, K	1
Junqueira, RG; Mares-Guia, M; Silva, E	1
Libby, PR; Porter, CW	1
Jennings, FW	1
Englund, PT; Shapiro, TA	1
Brun, R; Kunz, C	1
Jefferies, D; Jenni, L	1
Karvonen, E	1
Rathaur, S; Walter, RD; Wittich, RM	1
Balber, AE; Frommel, TO	1
Gupta, S; Shukla, OP; Walter, RD	1
Bitonti, AJ; Dumont, JA; McCann, PP	1
Karvonen, E; Kauppinen, L; Partanen, T; Pösö, H	1
Cobb, CC; Farwell, GE; LeGrand, EK	1
Bodley, AL; McGarry, MW; Shapiro, TA	1
Alvarez Bujidos, ML; Balaña Fouce, R; Cubria, JC; Ordoñez, D; Reguera, R	1
Alvarez-Bujidos, ML; Balaña Fouce, R; Cubría, JC; Negro, A; Ordóñez, D; Ortiz, AI	1
Brown, DG; Jenkins, TC; Lane, AN; Neidle, S	1
Baltz, T; Barrett, MP; Denise, H; Giroud, C; Zhang, ZQ	1
Scott, AG; Tait, A; Turner, CM	1
Reinert, KE	1
Asiri, SA; Ogbunude, PO	1
Atsriku, C; Grant, MH; Skellern, GG; Watson, DG	1
Rudenko, G; Sheader, K; te Vruchte, D	1
Coombs, GH; Goyeneche, D; Jean-Moreno, V; Rojas, R; Walker, J	1
Anene, BM; Barrett, MP; Brock, JM; De Koning, HP; Ezeokonkwo, RC; Mmesirionye, TI; Tettey, JN	1
Agama, KK; Antony, S; Fisher, RJ; Marchand, C; Pommier, Y; Stephen, AG; Thibaut, L	1
Akpa, PO; Anene, BM; Eze, CA; Ezeokonkwo, RC	1
Brown, DE; Collyer, CA; Dooley, DM; Elmore, BO; Guss, JM; Hilmer, KM; McGrath, AP; Shepard, EM	1
Hwang, SJ; Maede, Y; Murakami, M; Nakamura, K; Ohta, H; Sasaki, N; Takiguchi, M; Wickramasekara Rajapakshage, BK; Yamasaki, M	1
Nagem, RA; Pereira, MT; Perilo, CS; Santoro, MM	1
Zsila, F	1
Inoue, N; Molefe, NI; Suganuma, K	1
Freza, S; Samsonov, SA; Zsila, F	1
Auma, JE; Chemuliti, JK; Gitonga, PK; Kurgat, RK; Mdachi, RE; Murilla, GA; Ndung'u, K; Ngae, GN; Thuita, JK; Thungu, DK	1
Changtam, C; de Koning, HP; Gould, MK; Ibrahim, H; Sajid, MS; Suksamrarn, A	1
Al-Salabi, MI; Ali, JA; de Koning, HP; El-Sabbagh, N; Ho, W; Ibrahim, HM; Koomen, GJ; Rodenko, B; Teka, IA; Wanner, MJ	1

Other Studies

40 other study(ies) available for diminazene aceturate and pentamidine

Article	Year
DNA binding affinity of bisguanidine and bis(2-aminoimidazoline) derivatives with in vivo antitrypanosomal activity. Journal of medicinal chemistry, 2006, Jun-15, Volume: 49, Issue:12 Topics: Animals; DNA; Female; Guanidines; Imidazolines; Mice; Nucleoside Transport Proteins; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma brucei rhodesiense; Trypanosomiasis, African	2006
Discovery of N-(2-aminoethyl)-N-benzyloxyphenyl benzamides: New potent Trypanosoma brucei inhibitors. Bioorganic & medicinal chemistry, 2017, 03-01, Volume: 25, Issue:5 Topics: Administration, Oral; Animals; Antiprotozoal Agents; Benzamides; Biological Availability; Drug Discovery; Mice; Structure-Activity Relationship; Trypanosoma brucei brucei; Trypanosomiasis	2017
Assessment of a pretomanid analogue library for African trypanosomiasis: Hit-to-lead studies on 6-substituted 2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]thiazine 8-oxides. Bioorganic & medicinal chemistry letters, 2018, 01-15, Volume: 28, Issue:2 Topics: Administration, Oral; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Mice; Molecular Structure; Nitroimidazoles; Small Molecule Libraries; Structure-Activity Relationship; Trypanosomiasis, African	2018
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity. Journal of medicinal chemistry, 2018, 12-27, Volume: 61, Issue:24 Topics: Animals; Antiparasitic Agents; Antitubercular Agents; Caco-2 Cells; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Entamoeba histolytica; Giardia lamblia; Humans; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Nitroimidazoles; Structure-Activity Relationship	2018
Competitive parabolic inhibition of bovine trypsin by bis-benzamidines. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1992, Volume: 25, Issue:9 Topics: Animals; Cattle; Diminazene; In Vitro Techniques; Kinetics; Organoplatinum Compounds; Pentamidine; Structure-Activity Relationship; Substrate Specificity; Trypsin; Trypsin Inhibitors	1992
Inhibition of enzymes of polyamine back-conversion by pentamidine and berenil. Biochemical pharmacology, 1992, Aug-18, Volume: 44, Issue:4 Topics: Acetyltransferases; Animals; Diminazene; Humans; Kinetics; Leukemia L1210; Melanoma; Mice; Oxidoreductases Acting on CH-NH Group Donors; Pentamidine; Polyamine Oxidase	1992
Chemotherapy of CNS-trypanosomiasis: the combined use of diminazene aceturate or pentamidine with DL-alpha-difluoromethylornithine (DFMO). Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ), 1992, Volume: 43, Issue:2 Topics: Animals; Arsenicals; Central Nervous System Diseases; Diminazene; Drug Administration Schedule; Drug Therapy, Combination; Eflornithine; Female; Mice; Pentamidine; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	1992
Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:3 Topics: Animals; Diminazene; DNA Topoisomerases, Type I; DNA, Circular; DNA, Kinetoplast; Ethidium; Molecular Structure; Pentamidine; Phenanthridines; Restriction Mapping; Trypanocidal Agents; Trypanosoma	1990
In vitro drug sensitivity test for Trypanosoma brucei subgroup bloodstream trypomastigotes. Acta tropica, 1989, Volume: 46, Issue:5-6 Topics: Animals; Arsenicals; Diminazene; Hypoxanthine; Hypoxanthines; Leucine; Pentamidine; Phenanthridines; Suramin; Thymidine; Trypanocidal Agents; Trypanosoma brucei brucei	1989
The effect of trypanocidal drugs on the transmission of Trypanosoma brucei brucei by Glossina morsitans centralis. Acta tropica, 1987, Volume: 44, Issue:1 Topics: Animals; Diminazene; Pentamidine; Phenanthridines; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African; Tsetse Flies	1987
Inhibition of diamine oxidase of rat small intestine by pentamidine and berenil (diminazene aceturate). Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17 Topics: Amidines; Amine Oxidase (Copper-Containing); Animals; Diminazene; Intestine, Small; Pentamidine; Rats; Structure-Activity Relationship	1987
Ascaris suum and Onchocerca volvulus: S-adenosylmethionine decarboxylase. Experimental parasitology, 1988, Volume: 65, Issue:2 Topics: Adenosylmethionine Decarboxylase; Animals; Ascaris; Carboxy-Lyases; Chromatography, Gel; Diminazene; Enzyme Activation; Female; Magnesium; Male; Mitoguazone; Onchocerca; Pentamidine; Polyethylene Glycols; Putrescine	1988
Flow cytofluorimetric analysis of drug accumulation by multidrug-resistant Trypanosoma brucei brucei and T. b. rhodesiense. Molecular and biochemical parasitology, 1987, Volume: 26, Issue:1-2 Topics: Acriflavine; Animals; Benzimidazoles; Diminazene; Drug Resistance; Ethidium; Flow Cytometry; Fluorescent Dyes; Humans; Indoles; Melarsoprol; Mice; Pentamidine; Suramin; Trypanocidal Agents; Trypanosoma brucei brucei	1987
Putrescine-activated S-adenosylmethionine decarboxylase from Acanthamoeba culbertsoni. Molecular and biochemical parasitology, 1987, Volume: 23, Issue:3 Topics: Adenosylmethionine Decarboxylase; Amoeba; Animals; Carboxy-Lyases; Cell-Free System; Diminazene; Enzyme Activation; Kinetics; Metals; Mitoguazone; Molecular Weight; Pentamidine; Putrescine	1987
Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone). The Biochemical journal, 1986, Aug-01, Volume: 237, Issue:3 Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Male; Mitoguazone; Pentamidine; Putrescine; Rats; Rats, Inbred Strains; Spermidine; Spermine; Trypanocidal Agents; Trypanosoma brucei brucei	1986
Irreversible inhibition of putrescine-stimulated S-adenosyl-L-methionine decarboxylase by berenil and pentamidine. The Biochemical journal, 1985, Oct-01, Volume: 231, Issue:1 Topics: Adenosylmethionine Decarboxylase; Amidines; Animals; Carboxy-Lyases; Diminazene; Diphenylamine; Liver; Pentamidine; Pseudomonas aeruginosa; Putrescine; Rats; S-Adenosylmethionine; Saccharomyces cerevisiae	1985
Clinical observations on Babesia gibsoni and Babesia canis infections in dogs. Journal of the American Veterinary Medical Association, 1982, Mar-01, Volume: 180, Issue:5 Topics: Animals; Babesiosis; Diminazene; Dog Diseases; Dogs; Erythrocytes; Female; Japan; Pentamidine	1982
Drug cytotoxicity assay for African trypanosomes and Leishmania species. The Journal of infectious diseases, 1995, Volume: 172, Issue:4 Topics: Acid Phosphatase; Amphotericin B; Animals; Camptothecin; Diminazene; Drug Evaluation, Preclinical; Leishmania donovani; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei	1995
Putrescine uptake inhibition by aromatic diamidines in Leishmania infantum promastigotes. Biochemical pharmacology, 1994, May-18, Volume: 47, Issue:10 Topics: Amidines; Animals; Diminazene; Indoles; Kinetics; Leishmania infantum; Pentamidine; Putrescine; Stilbamidines	1994
Aromatic diamidines are reversible inhibitors of porcine kidney diamine oxidase. Biochemical pharmacology, 1993, Mar-24, Volume: 45, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Amine Oxidase (Copper-Containing); Animals; Benzamidines; Binding Sites; Diminazene; Kidney; Kinetics; Pentamidine; Stilbamidines; Swine	1993
NMR and molecular modeling studies of the interaction of berenil and pentamidine with d(CGCAAATTTGCG)2. European journal of biochemistry, 1993, May-01, Volume: 213, Issue:3 Topics: Base Sequence; Binding Sites; Crystallography; Diminazene; DNA; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Oligodeoxyribonucleotides; Pentamidine; Trypanocidal Agents	1993
A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity. Molecular and biochemical parasitology, 1995, Volume: 73, Issue:1-2 Topics: Adenosine; Animals; Arsenicals; Biological Transport, Active; Carrier Proteins; Diminazene; Drug Resistance; Kinetics; Pentamidine; Receptors, Purinergic P2; Trypanocidal Agents; Trypanosoma	1995
Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites. Experimental parasitology, 1997, Volume: 86, Issue:3 Topics: Adenine; Adenosine; Animals; Arsenicals; Diminazene; Dose-Response Relationship, Drug; Drug Resistance; Enzyme Inhibitors; Female; Inosine; Melarsoprol; Mice; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei	1997
DNA multimode interaction with berenil and pentamidine; double helix stiffening, unbending and bending. Journal of biomolecular structure & dynamics, 1999, Volume: 17, Issue:2 Topics: Animals; Cattle; Diminazene; DNA; DNA, Complementary; Intercalating Agents; Kinetics; Ligands; Models, Theoretical; Nucleic Acid Conformation; Pentamidine; Temperature; Trypanocidal Agents	1999
In vitro effect of diamidines on intracellular polyamines of Acanthamoeba polyphaga. Drugs under experimental and clinical research, 2001, Volume: 27, Issue:4 Topics: Acanthamoeba; Animals; Antiprotozoal Agents; Benzamidines; Diminazene; Humans; Pentamidine; Polyamines; Pyridines; Robenidine	2001
The effect of inducing agents on the metabolism of trypanocidal diamidines by isolated rat hepatocytes. Chemico-biological interactions, 2003, Dec-15, Volume: 146, Issue:3 Topics: Animals; Chromatography, Liquid; Cytochrome P-450 Enzyme System; Diminazene; Enzyme Induction; Hepatocytes; Humans; In Vitro Techniques; Male; Methylcholanthrene; Nitriles; Pentamidine; Phenobarbital; Pyrethrins; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Trypanocidal Agents	2003
Bloodstream form-specific up-regulation of silent vsg expression sites and procyclin in Trypanosoma brucei after inhibition of DNA synthesis or DNA damage. The Journal of biological chemistry, 2004, Apr-02, Volume: 279, Issue:14 Topics: Animals; Antiprotozoal Agents; Aphidicolin; Blood; Diminazene; DNA Damage; Enzyme Inhibitors; Gene Silencing; Genes, Reporter; Green Fluorescent Proteins; Luminescent Proteins; Membrane Glycoproteins; Pentamidine; Protozoan Proteins; RNA Polymerase I; S Phase; Suramin; Transcription, Genetic; Trypanocidal Agents; Trypanosoma brucei brucei; Up-Regulation; Variant Surface Glycoproteins, Trypanosoma	2004
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays. Experimental parasitology, 2006, Volume: 112, Issue:1 Topics: Acid Phosphatase; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Berberine Alkaloids; Bisbenzimidazole; Camptothecin; Cell Line; Diminazene; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Luciferases, Firefly; Luminescent Agents; Macrophages; Monocytes; Pentamidine; Quercetin; Topoisomerase I Inhibitors	2006
A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats. Parasitology, 2006, Volume: 132, Issue:Pt 1 Topics: Animals; Diminazene; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Resistance; Female; Parasitic Sensitivity Tests; Pentamidine; Random Allocation; Rats; Recurrence; Time Factors; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis, African	2006
Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1. Nucleic acids research, 2007, Volume: 35, Issue:13 Topics: Antineoplastic Agents; Benzamidines; Diminazene; DNA; DNA, Single-Stranded; Drug Evaluation, Preclinical; Electrochemistry; Humans; Kinetics; Luminescent Measurements; Pentamidine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Thymidine	2007
Comparative efficacy assessment of pentamidine isethionate and diminazene aceturate in the chemotherapy of Trypanosoma brucei brucei infection in dogs. Veterinary parasitology, 2008, Feb-14, Volume: 151, Issue:2-4 Topics: Animals; Blood Cell Count; Body Temperature; Diminazene; Dog Diseases; Dogs; Enzymes; Female; Hemoglobins; Male; Pentamidine; Time Factors; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosomiasis	2008
Structure and inhibition of human diamine oxidase. Biochemistry, 2009, Oct-20, Volume: 48, Issue:41 Topics: Amine Oxidase (Copper-Containing); Animals; Binding Sites; Calcium; Copper; Crystallography, X-Ray; Dimerization; Diminazene; Drosophila; Humans; Kinetics; Metallothionein; Models, Molecular; Pentamidine; Promoter Regions, Genetic; Protein Conformation; Substrate Specificity; X-Ray Diffraction	2009
Development and characterization of a strain of Babesia gibsoni resistant to diminazene aceturate in vitro. The Journal of veterinary medical science, 2010, Volume: 72, Issue:6 Topics: Animals; Antiprotozoal Agents; Babesia; Babesiosis; Cell Division; Clindamycin; Diminazene; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Doxycycline; Drug Resistance; Erythrocytes; Metronidazole; Pentamidine	2010
Structural binding evidence of the trypanocidal drugs berenil and pentacarinate active principles to a serine protease model. International journal of biological macromolecules, 2010, Volume: 46, Issue:5 Topics: Animals; Calorimetry; Cattle; Crystallography, X-Ray; Diminazene; Models, Molecular; Pentamidine; Thermodynamics; Trypanocidal Agents; Trypsin; Trypsin Inhibitors	2010
Glycosaminoglycans are potential pharmacological targets for classic DNA minor groove binder drugs berenil and pentamidine. Physical chemistry chemical physics : PCCP, 2015, Oct-14, Volume: 17, Issue:38 Topics: Antiprotozoal Agents; Chondroitin Sulfates; Circular Dichroism; Diminazene; DNA; Glycosaminoglycans; Pentamidine; Spectrophotometry, Ultraviolet	2015
An ATP-Based Luciferase Viability Assay for Animal African Trypanosomes Using a 96-Well Plate. Methods in molecular biology (Clifton, N.J.), 2017, Volume: 1601 Topics: Adenosine Triphosphate; Animals; Cell Survival; Diminazene; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Luciferases; Pentamidine; Trypanocidal Agents; Trypanosoma brucei brucei; Trypanosoma congolense; Trypanosomiasis, African	2017
In silico analysis of heparin and chondroitin sulfate binding mechanisms of the antiprotozoal drug berenil and pentamidine. Carbohydrate research, 2019, Aug-01, Volume: 482 Topics: Antiprotozoal Agents; Chondroitin Sulfates; Computer Simulation; Diminazene; Heparin; Hydrogen Bonding; Molecular Conformation; Molecular Dynamics Simulation; Pentamidine; Quantum Theory; Thermodynamics	2019
Differential virulence of Trypanosoma brucei rhodesiense isolates does not influence the outcome of treatment with anti-trypanosomal drugs in the mouse model. PloS one, 2020, Volume: 15, Issue:11 Topics: Animals; Diminazene; Disease Models, Animal; Drug Resistance; Kenya; Male; Melarsoprol; Mice; Pentamidine; Suramin; Treatment Outcome; Trypanocidal Agents; Trypanosoma brucei rhodesiense; Trypanosomiasis, African; Uganda; Virulence	2020
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Antimalarials; Cell Line; Curcumin; Diarylheptanoids; Humans; Inhibitory Concentration 50; Leishmania; Molecular Structure; Trypanocidal Agents; Trypanosoma	2010
Synthesis of marine-derived 3-alkylpyridinium alkaloids with potent antiprotozoal activity. ACS medicinal chemistry letters, 2011, Dec-08, Volume: 2, Issue:12 Topics:	2011