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dimethylmyleran and busulfan

dimethylmyleran has been researched along with busulfan in 22 studies

*Busulfan: An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. [MeSH]

*Busulfan: An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen. [MeSH]

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199017 (77.27)18.7374
1990's5 (22.73)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cobbold, SP; Leong, LY; Qin, S; Waldmann, H1
DeGregorio, MW; Rappeport, JM; Smith, BR; Wiebe, VJ1
Gengozian, N; Good, RA; Ishii, E1
Lapidot, T; Reisner, Y; Salomon, O; Singer, TS; Terenzi, A1
Deeg, HJ; Luk, K; Shulman, HM; Shuman, WB; Storb, R1
Amos, D; Appelbaum, FR; Buckner, CD; Clift, RA; Doney, KC; Fefer, A; Hill, RS; Kanfer, EJ; Shulman, HM; Storb, R1
Appelbaum, FR; Buckner, CD; Clift, RA; Doney, KC; Hill, RS; Kanfer, EJ; Petersen, FB; Shulman, HM; Stewart, P; Storb, R1
Floersheim, GL; Torhorst, J2
van Bekkum, DW1
Floersheim, GL3
Blackett, NM; Standen, GR1
Hemsworth, BN1
Abkowitz, JL; Guttorp, P; Linenberger, ML; Newton, MA; Persik, M1
Boog, CJ; de Vries-van der Zwan, A; de Waal, LP; van der Pol, MA1
Blackett, NM; Twentyman, PR1
BIERMAN, HR; KELLY, KH; KNUDSON, AG; MAEKAWA, T; TIMMIS, GM1
ALEXANDER, P; MIKULSKI, ZB1
ELSON, LA; FLOERSHEIM, GL1
CLIFFORD, P; CLIFT, RA; KHAN, AG; TIMMIS, GM1

Reviews

2 review(s) available for dimethylmyleran and busulfan

ArticleYear
Pharmacology of agents used in bone marrow transplant conditioning regimens.
    Critical reviews in oncology/hematology, 1992, Volume: 13, Issue:3

    Topics: Antineoplastic Agents; Bone Marrow Transplantation; Busulfan; Carmustine; Hematopoiesis; Humans; Immunosuppressive Agents; Melphalan; Whole-Body Irradiation

1992
Conditioning regimens for marrow grafting.
    Seminars in hematology, 1984, Volume: 21, Issue:2

    Topics: Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporins; Graft Enhancement, Immunologic; Graft Rejection; Graft vs Host Disease; Histocompatibility; Host vs Graft Reaction; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lymphocytes; Whole-Body Irradiation

1984

Other Studies

20 other study(ies) available for dimethylmyleran and busulfan

ArticleYear
Classical transplantation tolerance in the adult: the interaction between myeloablation and immunosuppression.
    European journal of immunology, 1992, Volume: 22, Issue:11

    Topics: Animals; Antibodies, Monoclonal; Bone Marrow; Bone Marrow Transplantation; Busulfan; CD4 Antigens; CD8 Antigens; Chimera; Female; Immune Tolerance; Male; Mice; Mice, Inbred Strains; Skin Transplantation; Transplantation Immunology

1992
Influence of dimethyl myleran on tolerance induction and immune function in major histocompatibility complex-haploidentical murine bone-marrow transplantation.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Oct-01, Volume: 88, Issue:19

    Topics: Animals; Antibody Formation; Bone Marrow Transplantation; Busulfan; Cytotoxicity, Immunologic; Immune Tolerance; Immunity, Cellular; Lymphocyte Culture Test, Mixed; Major Histocompatibility Complex; Mice; Mice, Inbred Strains; Radiation Chimera

1991
Enhancement by dimethyl myleran of donor type chimerism in murine recipients of bone marrow allografts.
    Blood, 1989, May-15, Volume: 73, Issue:7

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Female; Graft Rejection; Hematopoiesis; Immunization; Lectins; Leukocyte Count; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Peanut Agglutinin; Preoperative Care; Radiation Chimera; Spleen; T-Lymphocytes; Tissue Donors; Whole-Body Irradiation

1989
Induction of hepatic veno-occlusive disease in dogs.
    The American journal of pathology, 1987, Volume: 126, Issue:1

    Topics: Animals; Busulfan; Buthionine Sulfoximine; Cyclophosphamide; Disease Models, Animal; Dog Diseases; Dogs; Hepatic Veno-Occlusive Disease; Liver; Melphalan; Methionine Sulfoximine; Methotrexate; Monocrotaline; Pyrrolizidine Alkaloids; Radiation Injuries, Experimental; Radiography

1987
Allogeneic and syngeneic marrow transplantation following high dose dimethylbusulfan, cyclophosphamide and total body irradiation.
    Bone marrow transplantation, 1987, Volume: 1, Issue:4

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Cyclophosphamide; Drug Administration Schedule; Hepatic Veno-Occlusive Disease; Humans; Infant; Leukemia; Middle Aged; Premedication; Pulmonary Fibrosis; Transplantation, Homologous; Transplantation, Isogeneic; Whole-Body Irradiation

1987
Phase I study of high-dose dimethylbusulfan followed by autologous bone marrow transplantation in patients with advanced malignancy.
    Cancer treatment reports, 1987, Volume: 71, Issue:1

    Topics: Adolescent; Adult; Bone Marrow Transplantation; Busulfan; Child; Combined Modality Therapy; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms

1987
Inhibition by lymph node cells and promotion by fetal hepatocytes of murine tumours without or with chemotherapy.
    Oncology, 1981, Volume: 38, Issue:6

    Topics: Ancitabine; Animals; Antineoplastic Agents; Busulfan; Carcinogens; Cyclophosphamide; Female; Killer Cells, Natural; Leukemia, Experimental; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Moloney murine leukemia virus; Neoplasms, Experimental; Sarcoma, Experimental

1981
Decreased tolerance to dimethyl-myleran, cyclophosphamide and radiation in lymphoma-bearing mice.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:8

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Colony-Forming Units Assay; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Tolerance; Female; Humans; Lethal Dose 50; Lymphoma; Male; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Radiation Tolerance; Whole-Body Irradiation

1982
Effect of daily administration of cytotoxic drugs on the erythroid and granulocytic repopulating ability of rat bone marrow.
    Acta haematologica, 1980, Volume: 63, Issue:5

    Topics: Animals; Antineoplastic Agents; Busulfan; Cell Division; Cyclophosphamide; Erythrocytes; Granulocytes; Hematopoietic Stem Cells; Male; Rats; Time Factors

1980
Control of a human tumour (Ewing sarcoma) in mice by a single lethal dose of dimethyl-myleran and bone marrow.
    International journal of cancer, 1981, Jun-15, Volume: 27, Issue:6

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Dose-Response Relationship, Drug; Humans; Immunosuppression Therapy; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Sarcoma, Ewing

1981
Treatment of murine tumors with lethal doses of dimethylmyleran and autologous bone marrow.
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:8

    Topics: Animals; Bone Marrow Transplantation; Busulfan; Female; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Neoplasm Transplantation; Sarcoma, Experimental; Spleen; Transplantation, Autologous; Transplantation, Isogeneic

1981
Comparative effect of the isomers of dimethylmyleran on spermatogenesis in the rat.
    Chemico-biological interactions, 1981, Volume: 36, Issue:3

    Topics: Animals; Busulfan; Male; Rats; Rats, Inbred Strains; Spermatogenesis; Stereoisomerism; Testis; Time Factors

1981
Behavior of feline hematopoietic stem cells years after busulfan exposure.
    Blood, 1993, Oct-01, Volume: 82, Issue:7

    Topics: Animals; Bone Marrow Cells; Busulfan; Cats; Cells, Cultured; Clone Cells; Female; Glucosephosphate Dehydrogenase; Hematopoiesis; Hematopoietic Stem Cells; Phenotype; Probability; Stochastic Processes; Time Factors

1993
An alternative conditioning regimen for induction of specific skin graft tolerance across full major histocompatibility complex barriers.
    Transplant immunology, 1998, Volume: 6, Issue:3

    Topics: Animals; Busulfan; Cyclophosphamide; Female; H-2 Antigens; Immune Tolerance; Immunosuppressive Agents; Male; Mice; Mice, Inbred C57BL; Skin Transplantation; Survivors; Transplantation Conditioning; Transplantation, Homologous

1998
Action of cytotoxic agents on the erythroid system of the mouse.
    Journal of the National Cancer Institute, 1970, Volume: 44, Issue:1

    Topics: Animals; Antineoplastic Agents; Busulfan; Cell Division; Dactinomycin; Dose-Response Relationship, Drug; Erythrocytes; Gamma Rays; Methotrexate; Mice; Mice, Inbred C57BL; Nucleic Acid Synthesis Inhibitors; Vinblastine

1970
The influence of 1, 4-dimethylsulfonoxy-1, 4-dimethylbutane (CB 2348, dimethyl myleran) in neoplastic disease.
    Annals of the New York Academy of Sciences, 1958, Apr-24, Volume: 68, Issue:3

    Topics: Busulfan; Leadership; Neoplasms

1958
Differences in the response of leukaemia cells in tissue culture to nitrogen mustard and to dimethyl myleran.
    Biochemical pharmacology, 1961, Volume: 5

    Topics: Animals; Busulfan; Leukemia, Experimental; Mechlorethamine; Nitrogen Mustard Compounds; Research Design

1961
[Bone marrow transplantation after dimethyl myleran as a method of evaluation of the effect of mutagenetic influences on transplantation antigenicity of hematopoietic cells].
    Medicina experimentalis : International journal of experimental medicine, 1961, Volume: 4

    Topics: Bone Marrow; Bone Marrow Transplantation; Busulfan; Histocompatibility Antigens; Transplantation Immunology

1961
[Restoration of hematopoiesis following a lethal dose of dimethyl myleran by isologic bone marrow transplantation in mice. Experiments on modification of intolerance to homologous bone marrow by 6-mercaptopurine, aminochlorambucil and cortisone].
    Acta haematologica, 1961, Volume: 26

    Topics: Animals; Bone Marrow; Bone Marrow Transplantation; Busulfan; Chlorambucil; Cortisone; Hematopoiesis; Hematopoietic System; Mechlorethamine; Mercaptopurine; Mice; Nitrogen Mustard Compounds

1961
DIMETHYL MYLERAN THERAPY COMBINED WITH ABDOMINAL AORTIC OCCLUSION.
    British journal of cancer, 1964, Volume: 13

    Topics: Adolescent; Alopecia; Aorta; Aorta, Abdominal; Busulfan; Chemotherapy, Cancer, Regional Perfusion; Diarrhea; Eye Manifestations; Facial Neoplasms; Head and Neck Neoplasms; Keratosis; Neoplasms; Skull Neoplasms; Stomatitis; Thrombocytopenia; Toxicology; Vomiting

1964