dimethylglycine and sarcosine

dimethylglycine has been researched along with sarcosine in 189 studies

Research

Studies (189)

TimeframeStudies, this research(%)All Research%
pre-199018 (9.52)18.7374
1990's16 (8.47)18.2507
2000's55 (29.10)29.6817
2010's82 (43.39)24.3611
2020's18 (9.52)2.80

Authors

AuthorsStudies
Baker, JA; Lloyd, AW; Olliff, CJ; Rutt, KJ; Smith, G1
Amiri, P; Cava, M; Lee, KH; Lindquist, RN; Ottoboni, T1
Weiss, RC1
Lawson, JW; Reap, EA1
Domenech, CE; Lisa, TA; Lucchini, AE1
Hansen, SH; Tjørnelund, J1
Burns, S; Iles, RA; Johnson, A1
Cook, RJ; Porter, DH; Wagner, C1
Lin, M; Porter, DH; Wagner, C1
Bishop, PA; Smith, JF; Young, B1
Hoorn, AJ1
Dziuba, AN; Khokhlov, AP; Savchenko, IuN; Zavalishin, IA1
Davis, M; Knight, PK; Plummer, C; Ray, SP; Rose, RJ; Schlierf, HA1
Reeves, AG; Smith, EB; Ward, TN1
Freed, WJ2
Colman, N; Gardner, A; Gelernt, M; Herbert, V1
Glassman, AD; Goust, JM; Graber, CD; Kendall, R; Loadholt, CB1
Husain, M; Steenkamp, DJ1
Carlin, L; Roach, ES1
Herbert, V1
Gibson, P; Roach, ES1
Haidukewych, D; Rodin, EA1
Burns, SP; Iles, RA; Leonard, JV; Ryalls, M1
Laryea, MD; Ritgen, J; Wendel, U; Zass, R1
Dudman, NP; Kuchel, PW; Lundberg, P; Wilcken, DE1
Allen, RH; Lindenbaum, J; Stabler, SP1
Domenech, CE; Lisa, AT; Lucchesi, GI; Pallotti, C1
Laryea, MD; Pawliczek, S; Steinhagen, F; Wendel, U1
Lever, M1
Binzak, BA; Corstiaensen, JM; de Jong, JG; Engelke, UF; Heerschap, A; Moolenaar, SH; Poggi-Bach, J; Vockley, J; Wevers, RA1
Bolman, WM; Richmond, JA1
Hansen, TA; Jansen, M1
Hariganesh, K; Prathiba, J1
Binzak, BA; Engelke, UF; Hoard, HM; Hwu, WL; Lee, YM; Moolenaar, SH; Poggi-Bach, J; Vockley, J; Vockley, JG; Wevers, RA1
Cauller, PL; Dodd, M; Kendall, PR; Kern, JK; Mehta, PJ; Miller, VS1
Johnson, DW1
Beja, AM; Costa, MM; Paixão, JA; Rodrigues, VH1
Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Robson, RA2
Incharoensakdi, A; Waditee, R1
Chango, A; James, SJ; Melnyk, S; Pogribna, M; Pogribny, I; Yi, P1
Basran, J; Casaite, V; Harris, RJ; Meskys, R; Scrutton, NS1
Bollard, ME; Branstetter, D; Holmes, E; Lindon, JC; Mitchell, SC; Nicholson, JK; Zhang, W1
Allen, RH; Berthold, HK; Look, MP; Riezler, R; Rockstroh, JK; Sauerbruch, T; Schliefer, K; Stabler, SP1
Basran, A; Basran, J; Bhanji, N; Meskys, R; Mistry, S; Nietlispach, D; Scrutton, NS1
Lachowicz, TM; Obłak, E; Witek, S; Łuczyński, J1
Lacroix, J; Laryea, MD; Liet, JM; Mitchell, G; Morin, C; Morneau, S; Pelletier, V; Robinson, BH; Wendel, U1
Balkenhol, N; Hafner, D; Hohlfeld, T; Laryea, MD; Schwahn, BC; Wendel, U1
Holm, PI; Kvalheim, G; Lien, EA; Ueland, PM1
FRISELL, WR; JOHNSTON, JM; MACKENZIE, CG1
FRISELL, WR; MACKENZIE, CG1
Cai, Q; Ma, D1
Aimone, LD; Albom, M; Angeles, TS; Ator, MA; Dionne, CA; Gingrich, DE; Hudkins, RL; Iqbal, MA; Mallamo, JP; Meyer, SL; Reddy, DR; Robinson, C; Ruggeri, BA; Singh, J; Vaught, JL; Yang, S1
Bleie, Ø; Holm, PI; Lien, EA; Nordrehaug, JE; Nygård, O; Refsum, H; Ueland, PM1
Busch, M; Franke, C; Franke, S; Klemm, A; Lang, D; Müller, A; Passlick-Deetjen, J; Stein, G1
Castro, C; Collinsová, M; Evans, JC; Garrow, TA; Gratson, AA; Jiracek, J; Ludwig, ML1
Barile, M; Brandsch, R; Brizio, C; Bufano, D; Indiveri, C; Pochini, L1
Chambers, ST; George, PM; Lee, MB; Lever, M; McGregor, DO; Slow, S1
Blom, HJ; den Heijer, M; Holm, PI; Keijzer, MB; Midttun, Ø; Ueland, PM; Vollset, SE1
Chambers, ST; Dellow, WJ; George, PM; Lever, M; Scott, RS1
Barton, RH; Blancher, C; Cloarec, O; Craig, A; Dumas, ME; Gauguier, D; Holmes, E; Hudson, J; Lindon, JC; Nicholson, J; Trygg, J1
Ida, K; Moriguchi, T; Suzuki, H1
Bailey, NJ; Bollard, ME; Haselden, JN; Holmes, E; Nicholson, JK; Stanley, EG; Waterfield, CJ1
Alonso, JL; Cocinero, EJ; Lesarri, A; López, JC1
Brody, LC; Conley, M; Cox, C; Daly, SF; Kirke, PN; Mills, JL; Molloy, AM; Scott, JM; Ueland, PM1
Chinnery, P; Majamaa, K; Thorburn, D; Turnbull, D1
Altamura, M; Berettoni, M; Bressan, A; Calvani, F; Catrambone, F; Fattori, D; Felicetti, P; Fincham, CI; Gensini, M; Giuliani, S; Maggi, CA; Meini, S; Quartara, L; Rossi, C; Terracciano, R; Valenti, C1
Cai, Q; He, G; Ma, D1
Hasman, D; Innis, SM1
Anas, MK; Baltz, JM; Hammer, MA; Lever, M; Stanton, JA1
Chuang, MJ; Lai, MC; Lee, YC; Wang, CC; Wu, YC1
Han, X; Jiang, X; Ory, DS1
Brauers, G; Garrow, TA; Gehrmann, T; Häussinger, D; Heldt, K; Hoffmann, L; Lornejad-Schäfer, MR; Mayatepek, E; Schäfer, C; Schliess, F; Schwahn, BC1
Gaby, AR1
Blom, HJ; Clarke, R; de Groot, LC; Eussen, SJ; Hoefnagels, WH; Ueland, PM; van Staveren, WA1
Belkowski, SM; Davis, P; Lawson, BR; Lawson, JW; Whitesides, JF1
Atkinson, W; Chambers, ST; George, PM; Lever, M1
Hogan, DA; Szwergold, BS; Wargo, MJ1
Friesen, RW; Hasman, D; Innis, SM; Novak, EM1
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M1
Bailey, LJ; Bingman, CA; Fox, BG; McCoy, JG; Ng, YH; Phillips, GN; Weber, AP; Wrobel, R1
Dong, J; Liu, M; Xu, H; Yang, X; Yang, Y1
Gross, MJ; Ho, TC; Hogan, DA; Wargo, MJ; Whittaker, LA1
Jin Joo, H; Lee, E; Lee, J; Lee, JS; Mi Park, E; Oh, E1
Atkinson, W; Chambers, ST; George, PM; Lever, M; Slow, S1
Itoh, R; Nagai, T; Takahashi, T1
Atkinson, W; Chambers, ST; Elmslie, J; George, PM; Lever, M; Slow, S1
Combe, JP; Lafite, P; Levy, C; Leys, D; Scrutton, NS; Tralau, T1
Alisi, A; Carafa, M; Marianecci, C; Masotti, A; Ortaggi, G; Rinaldi, F; Vicennati, P1
Buyse, J; Cools, A; Janssens, GP; Kalmar, ID; Roose, P1
Buyse, J; Cools, A; Huyghebaert, G; Janssens, GP; Kalmar, ID; Roose, P; Verstegen, MW1
Ballano, G; Ge, NH; Maekawa, H; Toniolo, C1
Burke, LM; Castell, LM; Collins, J; Currell, K; Dziedzic, CE; King, DS; Spriet, LL; Stear, SJ; Syed, A1
Herrmann, W; Kirsch, SH; Obeid, R; Rabagny, Y1
Jiang, S; White, A1
Bay, BN; Davidson, AG; Hasman, D; Innis, SM; Slack, PJ1
Xia, RR1
Dietzen, DJ; Fujiwara, H; Jiang, X; Ory, DS; Platt, FM; Porter, FD; Schaffer, JE; Scherrer, DE; Sidhu, R; Speak, AO; te Vruchte, DT; Yanjanin, NM; Zhang, J1
Deker, PB; Fitzsimmons, LF; Flemer, S; Sarkar, IN; Wargo, MJ; Wurthmann, AS1
Bardag-Gorce, F; Caudill, M; French, BA; French, SW; Gorce, E; Kathirvel, E; Li, J; Li, XM; Malysheva, O; Morgan, K; Morgan, T; Oliva, J1
Atkinson, W; Chambers, ST; Elmslie, JL; George, PM; Lever, M; Molyneux, SL; Richards, AM; Slow, S1
Boyen, F; Janssens, GP; Kalmar, ID; Lauwaerts, A; Meyer, E; Sys, S; Vanhauteghem, D1
Janssens, GP; Kalmar, ID; Maenner, K; Meulemans, G; Verstegen, MW; Zentek, J1
Aman, P; Andersson, SO; Hallmans, G; Johansson, JE; Kamal-Eldin, A; Moazzami, AA; Zhang, JX1
Huang, J; Jiang, L; Ren, P; Tang, H; Zhang, L1
Allen, RH; Caudill, MA; Devapatla, S; Jiang, X; Malysheva, OV; Perry, CA; Pressman, E; Stabler, SP; Vermeylen, F; West, AA; Yan, J1
Chambers, ST; Dellow, WJ; George, PM; Lever, M; McGregor, DO; Slow, S1
Chinnery, PF; Majamaa, K; Pfeffer, G; Thorburn, D; Turnbull, DM1
Atkinson, W; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Lever, M; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW1
Liu, Y; Liu, YQ; Morita, T; Sugiyama, K1
Geisel, J; Gortner, L; Hartmuth, K; Herrmann, W; Nijhout, HF; Obeid, R; Reed, MC; Rohrer, TR1
Antl, N; Bondia-Pons, I; Hanhineva, K; Juntunen, K; Moazzami, AA; Mykkänen, H; Poutanen, K1
Barto, R; Blom, HJ; Imbard, A; Jakobs, C; Kok, RM; Smith, DE; Smulders, YM1
Bonham, MP; Davidson, PW; Henderson, J; Kobrosly, RW; McAfee, AJ; McSorley, EM; Mulhern, MS; Myers, GJ; Shamlaye, CF; Strain, JJ; Thurston, SW; Ueland, PM; van Wijngaarden, E; Wallace, JM; Watson, GE1
Al Quobaili, F; Alsayed, R; Geisel, J; Obeid, R; Srour, S1
Blom, HJ; den Heijer, M; Hogeveen, M; Semmekrot, BA; Sporken, JM; Ueland, PM1
Boyen, F; Cox, E; Janssens, GP; Lauwaerts, A; Meyer, E; Sys, S; Vanhauteghem, D1
Bianchi, C; De Marco, M; Lauwaerts, A; Nery, J; Pozzo, L; Prola, L; Schiavone, A; Sterpone, L1
Cole, D; Cox, SE; da Costa, KA; Dominguez-Salas, P; Dyer, RA; Fulford, AJ; Hennig, BJ; Innis, SM; Moore, SE; Prentice, AM; Waterland, RA; Zeisel, SH1
Ballesteros, M; Berrocal-Zaragoza, MI; Cavallé-Busquets, P; Fernandez-Ballart, JD; Fernàndez-Roig, S; Murphy, MM; Salat-Batlle, J; Ueland, PM1
Barto, R; Benoist, JF; Blom, HJ; Czerkiewicz, I; Imbard, A; Muller, F; Rigal, O; Schlemmer, D1
Collins, RE; Deming, JW1
Ebbing, M; Løland, KH; Nygård, O; Pedersen, EK; Schartum-Hansen, H; Seifert, R; Svingen, GF; Tell, GS; Ueland, PM1
Bjørge, T; de Vogel, S; Gregory, JF; Meyer, K; Nygård, O; Tell, GS; Tretli, S; Ueland, PM; Ulvik, A; Vollset, SE1
Brasili, E; Capuani, G; Finamore, A; Marini, F; Mengheri, E; Miccheli, A; Roselli, M; Sciubba, F; Tomassini, A1
Dyer, RA; Innis, SM; King, DJ; Mulder, KA; Wu, BT1
Fitzsimmons, LF; Hampel, KJ; LaBauve, AE; Meadows, JA; Nock, AM; Wargo, MJ1
Bashir, A; Bremer, E; Hoffmann, T; Smits, SH1
Bønaa, KH; Ebbing, M; Mellgren, G; Nilsen, DW; Nordrehaug, JE; Nygård, O; Pedersen, ER; Schartum-Hansen, H; Seifert, R; Svingen, GF; Ueland, PM; Øyen, J1
Awwad, HM; Geisel, J; Kirsch, SH; Obeid, R1
Chen, SD; Deng, YL; Huang, FJ; Jia, W; Liu, JJ; Ma, JF; Ren, RJ; Tang, HD; Wang, G; Wang, Y; Xu, W; Xu, XH; Zhang, YN; Zhao, AH; Zhou, Y1
Argüelles, M; Bamia, C; Barricarte, A; Bjørge, T; Boutron-Ruault, M; Bueno-de-Mesquita, HB; Cottet, V; de Vogel, S; Dorronsoro, M; Duarte-Salles, T; Eussen, SJ; Freisling, H; Grioni, S; Gunter, MJ; Hansen, L; Huerta, JM; Jakszyn, P; Johansson, M; Kaaks, R; Khaw, K; Kühn, T; Ljuslinder, I; Meyer, K; Naska, A; Nitter, M; Norgård, B; Nygård, O; Palli, D; Panico, S; Peeters, PH; Racine, A; Riboli, E; Sánchez, M; Stepien, M; Tjønneland, A; Trichopoulou, A; Tumino, R; Ueland, PM; Ulvik, A; van Kranen, H; Vineis, P; Vollset, SE; Wareham, N; Weiderpass, E1
Loukachevitch, LV; Luka, Z; Newcomer, ME; Pakhomova, S; Wagner, C1
Banwat, E; Chetwood, J; Crossey, MM; Dona, AC; Duguru, M; Fye, HK; Garside, DA; Holmes, E; Kasstan, B; Khan, SA; Ladep, NG; Lemoine, M; Lewis, MR; Nicholson, JK; Njai, HF; Njie, R; Okeke, E; Shimakawa, Y; Taal, M; Taylor-Robinson, SD; Thillainayagam, AV; Thursz, MR; Wijeyesekera, A1
Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S1
Chambers, ST; Elmslie, JL; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Parry-Strong, A; Slow, S1
Abele, H; Bernhard, W; Franz, AR; Heni, M; Koch, V; Kunze, R; Maas, C; Poets, CF; Raith, M1
Jiang, L1
Hamill, LL; Keaveney, EM; McNulty, H; Molloy, AM; Piironen, V; Price, RK; Shewry, PR; Strain, JJ; Ueland, PM; von Reding, W; Wallace, JM; Ward, JL; Ward, M; Welch, RW1
Apalset, EM; Gjesdal, CG; Lysne, V; Meyer, K; Nygård, OK; Svingen, GF; Tell, GS; Ueland, PM; Vollset, SE; Øyen, J1
Chen, H; Giese, TJ; Panteva, MT; York, DM1
Clish, C; Engström, G; Gerszten, RE; Magnusson, M; Melander, O; Nilsson, P; Wang, TJ1
Berger, H; Caudill, MA; Croxford, R; El-Sohemy, A; Kim, YI; Lausman, AY; Ly, A; Malysheva, O; Masih, S; Nielsen, DE; O'Connor, DL; Plumptre, L; Sohn, KJ; Visentin, CE1
Berge, RK; Bjørndal, B; Lysne, V; Nordrehaug, JE; Nygård, O; Skorve, J; Vik, R1
Chambers, CD; Coles, CD; Jones, KL; Kable, JA; Keen, CL; Kulikovsky, Y; Pedersen, TL; Uriu-Adams, JY; Wertelecki, W; Yevtushok, L1
Cavallé-Busquets, P; Fernandez-Ballart, JD; Murphy, MM; Solé-Navais, P1
Berge, RK; Bjørndal, B; Lysne, V; Midttun, Ø; Nygård, O; Olsen, T; Pedersen, ER; Strand, E; Svingen, GF; Ueland, PM1
Babuska, V; Dobra, J; Racek, J; Rajdl, D; Stehlik, P; Trefil, L1
Edashige, K; Manabe, N; Nagai, T; Sasaki, K; Somfai, T; Takahashi, T1
Caudill, MA; Gamble, MV; Graziano, JH; Hall, MN; Howe, CG; Ilievski, V; Islam, T; Liu, X; Lomax-Luu, AM; Malysheva, O; Parvez, F; Shahriar, H; Siddique, AB; Uddin, MN1
Bai, K; Kou, T; Niu, Y; Wan, X; Wang, C; Wang, T; Xu, W; Zhang, J; Zhang, L1
Chan, MH; Chen, HH; Chen, YC; Lee, MY; Lin, JC1
Gylling, B; Häggström, J; Hallmans, G; Hultdin, J; Johansson, I; Myte, R; Palmqvist, R; Schneede, J; Ueland, PM; Van Guelpen, B1
Bodis, M; Geisel, J; Herrmann, M; Herrmann, W; Hübner, U; Kirsch, SH; Laufs, U; Pusceddu, I; Wagenpfeil, S; Werner, C; Widmann, T1
Assaretti, S; Carru, C; Forteschi, M; Mangoni, AA; Pintus, G; Sotgia, S; Zinellu, A1
Awwad, HM; Geisel, J; Keller, M; Obeid, R1
Chambers, ST; George, PM; Lever, M; McEntyre, CJ1
Deng, YC; Lai, MC; Lai, SJ1
Chan, MH; Chen, HH; Lee, MY; Lin, YR; Tseng, YJ; Tu, YS1
Fukuhara, K; Kikura-Hanajiri, R; Ohno, A1
Guo, LZ; Lu, WD; Pang, HQ; Shao, YH; Yu, H; Zhang, YQ; Zhao, BS1
Bai, K; Feng, C; Ge, X; Wang, A; Wang, T; Zhang, L; Zhao, Y1
Chau, CMY; Devlin, AM; Dyer, RA; Grunau, RE; Innis, SM; McCarthy, D; Wiedeman, AM; Yurko-Mauro, K1
Bai, K; Cai, J; Jiang, L; Lu, Y; Wang, T; Zhang, L; Zhao, Y; Zhu, J1
Bailey, LB; Bland, VL; Caudill, MA; Fisher, S; Fleming, JM; Hausman, DB; Kauwell, GPA; Kennedy, EM; Knight, AK; Malysheva, O; Park, HJ; Rosa, G; Smith, AK; Sokolow, A1
Bai, K; Feng, C; Jiang, L; Wang, T; Zhang, L; Zhao, Y; Zhu, S1
Cheng, ZY; Du, YF; Shi, HF; Wang, XL; Wei, Y; Wu, TC; Yang, J; Zuo, XF1
Lamers, Y; Mujica-Coopman, MF; Schroder, TH; Sinclair, G; Tan, A; Vallance, HD1
Fudge, DS; Hoang, C; Jain, G; McCord, C; Singh, K; Starksen, M; Yancey, P1
Balvers, MGJ; de Wit, NJW; Esser, D; Obeid, R; Smolders, L; Vissers, MMM1
Bitai, J; Cordes, DB; Slawin, AMZ; Smith, AD1
Guo, LZ; Lu, WD; Meng, XL; Shao, YH; Yang, T; Yu, H1
Endo, Y; Fujimori, K; Fukuda, T; Hashimoto, K; Kanno, A; Kyozuka, H; Murata, T; Ono, M; Sato, A; Yamaguchi, A; Yasuda, S1
Boyd, EF; Dutta, A; Gregory, GJ; Parashar, V1
Chan, MH; Chen, H; Chen, HH; Chen, L; Hsieh, CP1
Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E1
Benner, S; Eriguchi, Y; Kameno, Y; Kasai, K; Kato, Y; Kojima, M; Kosaka, H; Kuroda, M; Kuwabara, H; Munesue, T; Murayama, C; Nishimura, T; Okada, T; Ozaki, N; Tsuchiya, K; Yamasue, H; Yassin, W1
Wang, B; Wei, Y1
Benassi, L; D'Aversa, E; Giacomelli, L; Kaleci, S; Lasagni, C; Magnoni, C; Mirisola, V; Mucci, A; Odorici, G; Paganelli, A; Reali, E; Righi, V; Tarentini, E1
Albanes, D; Cai, H; Cai, Q; Eliassen, H; Elliott, P; Fornage, M; Gerszten, RE; Guasch-Ferré, M; Harada, S; Herrington, DM; Karaman, I; Lipworth, LP; Matthews, CE; Menni, C; Meyer, KA; Moore, SC; Ose, J; Palmer, ND; Pan, XF; Shu, XO; Tzoulaki, I; Ulrich, CM; Wagenknecht, LE; Wang, TJ; Yang, JJ; Yu, D; Zheng, W; Zhu, H1
Chen, SR; Han, F; Huang, LH; Huang, ZW; Liu, PP; Liu, YQ; Sugiyama, K; Wang, Q; Xiang, XS; Xing, QB1
Bai, K; Jiang, L; Li, Q; Wang, T; Zhang, J; Zhang, L1
Chan, MH; Chen, HH; Chen, ST; Hsieh, CP; Huang, CM; Lee, MY1
Bhardwaj, S; Chopra, C; Dhanjal, DS; Kuca, K; Nepovimova, E; Patocka, J; Plucar, B; Singh, R; Valis, M1
Hu, Y; Rao, K; Shi, S; Wang, Q; Yao, H; Zhang, Y1
Cao, Q; Jiang, C; Jiang, CX; Liu, X; Mao, S; Ni, Y; Yu, B; Zhang, J1
Bai, K; Jiang, L; Li, Q; Wang, T; Wei, C; Zhang, J; Zhang, L1
Shao, D; Shi, S; Song, Z; Wang, Z; Wu, S1

Reviews

6 review(s) available for dimethylglycine and sarcosine

ArticleYear
Treatment for mitochondrial disorders.
    The Cochrane database of systematic reviews, 2006, Jan-25, Issue:1

    Topics: Creatine; Dichloroacetic Acid; Humans; Mitochondrial Diseases; Sarcosine; Ubiquinone

2006
Natural approaches to epilepsy.
    Alternative medicine review : a journal of clinical therapeutic, 2007, Volume: 12, Issue:1

    Topics: Biotin; Carnitine; Diet; Dietary Supplements; Epilepsy; Fatty Acids, Essential; Folic Acid; Humans; Magnesium; Manganese; Melatonin; Sarcosine; Taurine; Vitamins

2007
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 12.
    British journal of sports medicine, 2010, Volume: 44, Issue:12

    Topics: Aged; Athletic Performance; Cysteine; Cystine; Cytochromes c; Dehydroepiandrosterone; Dietary Supplements; Dihydroxyacetone Phosphate; Exercise; Humans; Immunocompetence; Male; Middle Aged; Pyruvic Acid; Sarcosine; Testosterone

2010
Treatment for mitochondrial disorders.
    The Cochrane database of systematic reviews, 2012, Apr-18, Issue:4

    Topics: Creatine; Dichloroacetic Acid; Humans; Mitochondrial Diseases; Randomized Controlled Trials as Topic; Sarcosine; Thioctic Acid; Ubiquinone

2012
Early pregnancy B vitamin status, one carbon metabolism, pregnancy outcome and child development.
    Biochimie, 2016, Volume: 126

    Topics: Betaine; Carbon; Child; Child Development; Child, Preschool; Female; Fetal Growth Retardation; Folic Acid; Homocysteine; Humans; Infant; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Sarcosine; Vitamin B 12

2016
Millennium Nutrient N,N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders.
    Current medicinal chemistry, 2022, Volume: 29, Issue:15

    Topics: Autism Spectrum Disorder; Autistic Disorder; Child; Humans; Nutrients; Sarcosine

2022

Trials

33 trial(s) available for dimethylglycine and sarcosine

ArticleYear
Immunomodulating properties of dimethylglycine in humans.
    The Journal of infectious diseases, 1981, Volume: 143, Issue:1

    Topics: Adjuvants, Immunologic; Administration, Oral; Adolescent; Adult; Antibodies, Bacterial; Bacterial Vaccines; Clinical Trials as Topic; Double-Blind Method; Glycine; Humans; Immunity; Immunity, Cellular; Middle Aged; Sarcosine; Streptococcus pneumoniae

1981
A double-blind, placebo-controlled, crossover pilot trial of low dose dimethylglycine in patients with autistic disorder.
    Journal of autism and developmental disorders, 1999, Volume: 29, Issue:3

    Topics: Adolescent; Adult; Autistic Disorder; Child; Child, Preschool; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Pilot Projects; Psychiatric Status Rating Scales; Sarcosine; Video Recording

1999
Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder.
    Journal of child neurology, 2001, Volume: 16, Issue:3

    Topics: Autistic Disorder; Child; Child Development Disorders, Pervasive; Child, Preschool; Double-Blind Method; Female; Humans; Male; Neurologic Examination; Personality Assessment; Sarcosine; Treatment Outcome

2001
Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Antiretroviral Therapy, Highly Active; Biomarkers; Cystathionine; Cysteine; Fasting; Female; Folic Acid; HIV Infections; HIV-1; Homocysteine; Humans; Male; Methionine; Methylmalonic Acid; Middle Aged; Multivariate Analysis; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Sarcosine; Vitamin B 6

2001
Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.
    Kidney international, 2002, Volume: 61, Issue:3

    Topics: Aged; Betaine; Cross-Over Studies; Drug Therapy, Combination; Fasting; Female; Folic Acid; Hematinics; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Lipids; Male; Methionine; Middle Aged; Pyridoxine; Sarcosine

2002
The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial.
    The Journal of pediatrics, 2003, Volume: 142, Issue:1

    Topics: Child; Child, Preschool; Cross-Over Studies; Cytochrome-c Oxidase Deficiency; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Oxygen Consumption; Sarcosine; Treatment Outcome

2003
Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria.
    British journal of clinical pharmacology, 2003, Volume: 55, Issue:1

    Topics: Administration, Oral; Adult; Betaine; Female; Homocystinuria; Humans; Male; Sarcosine

2003
Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:2

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Betaine; Choline; Coronary Angiography; Dietary Supplements; Drug Administration Schedule; Fasting; Female; Folic Acid; Follow-Up Studies; Homocysteine; Humans; Male; Methionine; Methyltransferases; Middle Aged; Sarcosine; Sex Factors; Vitamin B 12; Vitamin B 6; Vitamin B Complex

2004
Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.
    Clinical nephrology, 2004, Volume: 61, Issue:3

    Topics: Arginine; Cross-Over Studies; Cystathionine; Enzyme-Linked Immunosorbent Assay; Female; Fluorescence; Glycation End Products, Advanced; Homocysteine; Humans; Kidneys, Artificial; Lysine; Male; Membranes, Artificial; Middle Aged; Polymers; Prospective Studies; Renal Dialysis; Sarcosine; Sulfones

2004
Dimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients.
    Clinical biochemistry, 2004, Volume: 37, Issue:11

    Topics: Adult; Aged; Betaine; Homocysteine; Humans; Kidney Failure, Chronic; Methionine; Middle Aged; Renal Dialysis; Sarcosine

2004
Evidence of choline depletion and reduced betaine and dimethylglycine with increased homocysteine in plasma of children with cystic fibrosis.
    The Journal of nutrition, 2006, Volume: 136, Issue:8

    Topics: Adolescent; Betaine; Case-Control Studies; Child; Choline Deficiency; Cystic Fibrosis; Homocysteine; Humans; Sarcosine

2006
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.
    The British journal of nutrition, 2007, Volume: 98, Issue:5

    Topics: Aged; Attention; Betaine; Choline; Cognition; Double-Blind Method; Drug Combinations; Female; Folic Acid; Homocysteine; Humans; Male; Memory; Neuropsychological Tests; Psychomotor Performance; Sarcosine; Vitamin B 12; Vitamin B Complex

2007
Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects.
    The American journal of clinical nutrition, 2008, Volume: 87, Issue:3

    Topics: Administration, Oral; Adult; Analysis of Variance; Area Under Curve; Betaine; Choline; Cross-Over Studies; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Double-Blind Method; Homocysteine; Humans; Male; Methionine; Sarcosine; Statistics, Nonparametric

2008
Plasma and urine betaine and dimethylglycine variation in healthy young male subjects.
    Clinical biochemistry, 2009, Volume: 42, Issue:7-8

    Topics: Adult; Betaine; Chromatography, High Pressure Liquid; Dietary Supplements; Female; Humans; Male; Sarcosine; Time Factors; Young Adult

2009
Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2009, Volume: 19, Issue:11

    Topics: Adult; Betaine; Biomarkers; Choline; Creatinine; Cross-Over Studies; Diet; Dietary Supplements; Folic Acid; Homocysteine; Humans; Lipids; Male; Sarcosine; Time Factors; Vitamin B 12; Young Adult

2009
Dietary N,N-dimethylglycine supplementation improves nutrient digestibility and attenuates pulmonary hypertension syndrome in broilers.
    Journal of animal physiology and animal nutrition, 2010, Volume: 94, Issue:6

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Digestion; Female; Hypertension, Pulmonary; Poultry Diseases; Sarcosine

2010
Dietary supplementation with dimethylglycine affects broiler performance and plasma metabolites depending on dose and dietary fatty acid profile.
    Journal of animal physiology and animal nutrition, 2011, Volume: 95, Issue:2

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Body Composition; Chickens; Diet; Dietary Fats; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids; Female; Hypertension, Pulmonary; Male; Poultry Diseases; Sarcosine; Soybean Oil; Thiobarbituric Acid Reactive Substances

2011
Plasma choline depletion is associated with decreased peripheral blood leukocyte acetylcholine in children with cystic fibrosis.
    The American journal of clinical nutrition, 2011, Volume: 93, Issue:3

    Topics: Acetylcholine; Adolescent; Betaine; Child; Child, Preschool; Choline; Cross-Sectional Studies; Cystic Fibrosis; Enzyme Replacement Therapy; Female; Humans; Leukocytes; Male; Methionine; Pancreatin; Sarcosine

2011
Tolerance and safety evaluation of N,N-dimethylglycine, a naturally occurring organic compound, as a feed additive in broiler diets.
    The British journal of nutrition, 2012, Volume: 107, Issue:11

    Topics: Animal Feed; Animals; Animals, Inbred Strains; Chickens; Dietary Supplements; Energy Intake; Female; Food Additives; Male; Meat; Performance-Enhancing Substances; Sarcosine; Tissue Distribution; Weight Gain

2012
Nuclear magnetic resonance-based metabolomics enable detection of the effects of a whole grain rye and rye bran diet on the metabolic profile of plasma in prostate cancer patients.
    The Journal of nutrition, 2011, Volume: 141, Issue:12

    Topics: 3-Hydroxybutyric Acid; Aged; Aged, 80 and over; Betaine; Cross-Over Studies; Diet; Homocysteine; Humans; Insulin; Magnetic Resonance Spectroscopy; Male; Metabolome; Metabolomics; Multivariate Analysis; Plant Preparations; Prostate-Specific Antigen; Prostatic Neoplasms; Sarcosine; Secale; Triticum; United States

2011
Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans.
    The American journal of clinical nutrition, 2012, Volume: 95, Issue:5

    Topics: Adult; Betaine; Biomarkers; Choline; Female; Fetal Blood; Fetus; Humans; Methionine; Pregnancy; Sarcosine; Young Adult

2012
Metabolomics reveals the metabolic shifts following an intervention with rye bread in postmenopausal women--a randomized control trial.
    Nutrition journal, 2012, Oct-22, Volume: 11

    Topics: Amino Acids, Branched-Chain; Betaine; Body Mass Index; Bread; Cross-Over Studies; Diabetes Mellitus, Type 2; Dietary Fiber; Female; Finland; Humans; Hypercholesterolemia; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Overweight; Postmenopause; Postprandial Period; Risk; Sarcosine; Secale; Seeds

2012
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period.
    Annals of clinical biochemistry, 2015, Volume: 52, Issue:Pt 3

    Topics: Aged; Betaine; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Humans; Male; Methylamines; Middle Aged; Overweight; Sarcosine; Taurine; Time Factors

2015
Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes.
    Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:5

    Topics: Adult; Aged; Betaine; Bezafibrate; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Homocysteine; Humans; Hypolipidemic Agents; Inositol; Male; Middle Aged; Sarcosine; Taurine; Young Adult

2014
Postprandial plasma betaine and other methyl donor-related responses after consumption of minimally processed wheat bran or wheat aleurone, or wheat aleurone incorporated into bread.
    The British journal of nutrition, 2015, Feb-14, Volume: 113, Issue:3

    Topics: Adult; Betaine; Bread; Choline; Cross-Over Studies; Dietary Fiber; Female; Folic Acid; Food Handling; Humans; Male; Postprandial Period; Sarcosine; Seeds; Triticum

2015
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine.
    Nutrients, 2016, Jan-12, Volume: 8, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Atherosclerosis; Dietary Supplements; Folic Acid; Healthy Volunteers; Homocysteine; Humans; Linear Models; Male; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Wine

2016
Supplementation with Folic Acid, but Not Creatine, Increases Plasma Betaine, Decreases Plasma Dimethylglycine, and Prevents a Decrease in Plasma Choline in Arsenic-Exposed Bangladeshi Adults.
    The Journal of nutrition, 2016, Volume: 146, Issue:5

    Topics: Adult; Arsenic; Bangladesh; Betaine; Choline; Creatine; Dietary Supplements; Environmental Exposure; Female; Folic Acid; Humans; Male; Middle Aged; Sarcosine; Tandem Mass Spectrometry; Vitamin B Complex; Young Adult

2016
One-carbon metabolites and telomere length in a prospective and randomized study of B- and/or D-vitamin supplementation.
    European journal of nutrition, 2017, Volume: 56, Issue:5

    Topics: Aged; Biomarkers; Body Mass Index; Calcium Carbonate; Carbon; Choline; Cross-Sectional Studies; Dietary Supplements; Double-Blind Method; Female; Folic Acid; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Methylmalonic Acid; Middle Aged; Pilot Projects; Prospective Studies; Sarcosine; Telomere; Telomere Homeostasis; Tetrahydrofolates; Vitamin B 12; Vitamin B 6; Vitamin B Complex; Vitamin D

2017
Trimethylamine-N-oxide and its biological variations in vegetarians.
    European journal of nutrition, 2017, Volume: 56, Issue:8

    Topics: Adult; Aged; Betaine; Biomarkers; Diet, Vegetarian; Female; Humans; Male; Methylamines; Middle Aged; Sarcosine; Single-Blind Method; Vegetarians; Vitamin B 12

2017
Effects of dimethylglycine sodium salt supplementation on growth performance, hepatic antioxidant capacity, and mitochondria-related gene expression in weanling piglets born with low birth weight1.
    Journal of animal science, 2018, Sep-07, Volume: 96, Issue:9

    Topics: Alanine Transaminase; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Antioxidants; Aspartate Aminotransferases; Case-Control Studies; Diet; Dietary Supplements; Female; Gene Expression Regulation; Hydrogen Peroxide; Infant, Low Birth Weight; Liver; Malondialdehyde; Mitochondria; Oxidation-Reduction; Parturition; Pregnancy; Sarcosine; Swine; Weaning

2018
Plasma Betaine Is Positively Associated with Developmental Outcomes in Healthy Toddlers at Age 2 Years Who Are Not Meeting the Recommended Adequate Intake for Dietary Choline.
    The Journal of nutrition, 2018, 08-01, Volume: 148, Issue:8

    Topics: Betaine; Child Development; Child, Preschool; Choline; Diet; Double-Blind Method; Female; Humans; Infant; Male; Nutritional Requirements; Nutritional Status; Recommended Dietary Allowances; Sarcosine

2018
Natural Choline from Egg Yolk Phospholipids Is More Efficiently Absorbed Compared with Choline Bitartrate; Outcomes of A Randomized Trial in Healthy Adults.
    Nutrients, 2019, Nov-13, Volume: 11, Issue:11

    Topics: Adult; Aged; Betaine; Choline; Cross-Over Studies; Double-Blind Method; Egg Yolk; Humans; Male; Middle Aged; Phospholipids; Sarcosine

2019
Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms.
    Molecular autism, 2021, 02-23, Volume: 12, Issue:1

    Topics: Administration, Intranasal; Adolescent; Adult; Autistic Disorder; Double-Blind Method; Facial Expression; Humans; Male; Metabolomics; Middle Aged; Oxytocin; Sarcosine; Social Behavior; Treatment Outcome; Young Adult

2021

Other Studies

150 other study(ies) available for dimethylglycine and sarcosine

ArticleYear
A comparison of glycine, sarcosine, N,N-dimethylglycine, glycinebetaine and N-modified betaines as liposome cryoprotectants.
    The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:6

    Topics: Amaranth Dye; Betaine; Cryoprotective Agents; Freezing; Glycine; Liposomes; Sarcosine

1992
Betaine:homocysteine methyltransferase from rat liver: purification and inhibition by a boronic acid substrate analog.
    Archives of biochemistry and biophysics, 1992, Volume: 292, Issue:1

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Boronic Acids; Chromatography, High Pressure Liquid; Enzyme Stability; Kinetics; Liver; Male; Methyltransferases; Molecular Weight; Rats; Rats, Inbred Strains; Sarcosine; Substrate Specificity

1992
Immunologic responses in healthy random-source cats fed N,N-dimethylglycine-supplemented diets.
    American journal of veterinary research, 1992, Volume: 53, Issue:5

    Topics: Adjuvants, Immunologic; Administration, Oral; Animal Feed; Animals; Antibodies, Viral; Caliciviridae; Cats; Cell Survival; Cells, Cultured; Female; Herpesviridae; Immunity, Cellular; Interferons; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Mutagens; Newcastle disease virus; Random Allocation; Sarcosine

1992
Stimulation of the immune response by dimethylglycine, a nontoxic metabolite.
    The Journal of laboratory and clinical medicine, 1990, Volume: 115, Issue:4

    Topics: Animals; Antibodies, Bacterial; Antibodies, Viral; Antigens, Bacterial; Antigens, Viral; Female; Glycine; Immunization; Lymphocyte Activation; O Antigens; Orthomyxoviridae; Rabbits; Salmonella typhi; Sarcosine

1990
Choline derivatives increase two different acid phosphatases in Rhizobium meliloti and Pseudomonas aeruginosa.
    Archives of microbiology, 1990, Volume: 153, Issue:6

    Topics: Acid Phosphatase; Atropine; Betaine; Choline; Culture Media; Phosphorylcholine; Pseudomonas aeruginosa; Quaternary Ammonium Compounds; Rhizobium; Sarcosine

1990
Gas chromatographic assay for N,N-dimethylglycine in urine.
    Journal of chromatography, 1990, Sep-14, Volume: 530, Issue:2

    Topics: Betaine; Chromatography, Gas; Gas Chromatography-Mass Spectrometry; Homocystinuria; Humans; Hyperglycemia; Indicators and Reagents; Mutagens; Sarcosine; Temperature

1990
Indirect measurement of betaine--homocysteine methyltransferase activity using 1H nmr spectroscopy.
    Biochemical Society transactions, 1991, Volume: 19, Issue:4

    Topics: Betaine-Homocysteine S-Methyltransferase; Fatty Acid Desaturases; Humans; Infant, Newborn; Magnetic Resonance Spectroscopy; Methyltransferases; Sarcosine

1991
Enzymatic properties of dimethylglycine dehydrogenase and sarcosine dehydrogenase from rat liver.
    Archives of biochemistry and biophysics, 1985, Volume: 243, Issue:2

    Topics: Anaerobiosis; Animals; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dimethylglycine Dehydrogenase; Enzyme Activation; Formaldehyde; Glycine; Kinetics; Mathematics; Mitochondria, Liver; Mitochondrial Proteins; Models, Chemical; Oxidoreductases, N-Demethylating; Rats; Sarcosine; Sarcosine Dehydrogenase; Tetrahydrofolates

1985
Measurement of dimethylglycine in biological fluids.
    Analytical biochemistry, 1985, Volume: 151, Issue:2

    Topics: Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dimethylglycine Dehydrogenase; Glycine; Humans; Mitochondrial Proteins; Oxidoreductases, N-Demethylating; Radioisotope Dilution Technique; Sarcosine; Substrate Specificity

1985
Effects of N,N-dimethylglycine on physiological response and performance in trained runners.
    The Journal of sports medicine and physical fitness, 1987, Volume: 27, Issue:1

    Topics: Adolescent; Adult; Female; Glycine; Humans; Male; Running; Sarcosine

1987
Dimethylglycine and chemically related amines tested for mutagenicity under potential nitrosation conditions.
    Mutation research, 1989, Volume: 222, Issue:4

    Topics: Amines; Betaine; Chemical Phenomena; Chemistry; Glycine; Mutagenicity Tests; Nitrites; Nitrosamines; Salmonella typhimurium; Sarcosine

1989
[Disorders of formaldehyde metabolism and its metabolic precursors in patients with multiple sclerosis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1989, Volume: 89, Issue:2

    Topics: Adolescent; Adult; Betaine; Enzyme Activation; Female; Formaldehyde; Glycine; Humans; Leucyl Aminopeptidase; Male; Middle Aged; Multiple Sclerosis; Neuroglia; Sarcosine

1989
Effects of N,N-dimethylglycine on cardiorespiratory function and lactate production in thoroughbred horses performing incremental treadmill exercise.
    The Veterinary record, 1989, Sep-02, Volume: 125, Issue:10

    Topics: Animals; Carbon Dioxide; Exercise Test; Heart Rate; Hemoglobins; Horses; Lactates; Muscles; Oxygen; Oxygen Consumption; Physical Exertion; Random Allocation; Sarcosine

1989
Dimethylglycine and reduction of mortality in penicillin-induced seizures.
    Annals of neurology, 1985, Volume: 17, Issue:2

    Topics: Animals; Anticonvulsants; Epilepsy; Female; Glycine; Penicillin G; Rats; Rats, Inbred Strains; Sarcosine

1985
Prevention of strychnine-induced seizures and death by the N-methylated glycine derivatives betaine, dimethylglycine and sarcosine.
    Pharmacology, biochemistry, and behavior, 1985, Volume: 22, Issue:4

    Topics: Animals; Anticonvulsants; Betaine; Female; Glycine; Mice; Sarcosine; Seizures; Strychnine

1985
Mutagenicity of dimethylglycine when mixed with nitrite: possible significance in human use of pangamates.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1980, Volume: 164, Issue:1

    Topics: Ascorbic Acid; Calcium Gluconate; Dose-Response Relationship, Drug; Glycine; Humans; Mutagens; Mutation; N-substituted Glycines; Nitrites; Propylamines; Salmonella; Sarcosine; Vitamin B Complex

1980
The effect of tetrahydrofolate on the reduction of electron transfer flavoprotein by sarcosine and dimethylglycine dehydrogenases.
    The Biochemical journal, 1982, Jun-01, Volume: 203, Issue:3

    Topics: Dimethylglycine Dehydrogenase; Flavoproteins; Kinetics; NADP; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Sarcosine; Sarcosine Dehydrogenase; Tetrahydrofolates

1982
N,N-dimethylglycine for epilepsy.
    The New England journal of medicine, 1982, Oct-21, Volume: 307, Issue:17

    Topics: Adult; Epilepsy; Glycine; Humans; Male; Sarcosine

1982
N,N-dimethylglycine for epilepsy.
    The New England journal of medicine, 1983, Mar-03, Volume: 308, Issue:9

    Topics: Epilepsy; Glycine; Humans; Mutagens; Sarcosine

1983
Failure of N,N-dimethylglycine in epilepsy.
    Annals of neurology, 1983, Volume: 14, Issue:3

    Topics: Adolescent; Adult; Child; Child, Preschool; Double-Blind Method; Epilepsy; Female; Glycine; Humans; Male; Sarcosine

1983
N,N-dimethylglycine shows no anticonvulsant potential.
    Annals of neurology, 1984, Volume: 15, Issue:4

    Topics: Animals; Epilepsy; Glycine; Mice; Sarcosine

1984
N,N-dimethylglycine, betaine, and seizures.
    Archives of neurology, 1984, Volume: 41, Issue:11

    Topics: Betaine; Epilepsy; Glycine; Humans; Sarcosine

1984
Methylgenesis from betaine in cystathionine-beta-synthase deficiency.
    Biochemical Society transactions, 1993, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Betaine; Child; Child, Preschool; Cystathionine gamma-Lyase; Homocystinuria; Humans; Methylation; Sarcosine

1993
Simultaneous determination of betaine and N,N-dimethylglycine in urine.
    Clinica chimica acta; international journal of clinical chemistry, 1994, Oct-31, Volume: 230, Issue:2

    Topics: Betaine; Child, Preschool; Chromatography, High Pressure Liquid; Homocystinuria; Humans; Reproducibility of Results; Sarcosine

1994
1H NMR determination of urinary betaine in patients with premature vascular disease and mild homocysteinemia.
    Clinical chemistry, 1995, Volume: 41, Issue:2

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Betaine; Creatinine; Glycine; Homocysteine; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Male; Regression Analysis; Sarcosine; Vascular Diseases

1995
Serum betaine, N,N-dimethylglycine and N-methylglycine levels in patients with cobalamin and folate deficiency and related inborn errors of metabolism.
    Metabolism: clinical and experimental, 1993, Volume: 42, Issue:11

    Topics: Adolescent; Adult; Aged; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Chromatography; Creatinine; Cystathionine beta-Synthase; Female; Folic Acid Deficiency; Gas Chromatography-Mass Spectrometry; Homocysteine; Humans; Male; Metabolism, Inborn Errors; Methionine; Methyltransferases; Middle Aged; Rats; Rats, Sprague-Dawley; Reference Values; Renal Insufficiency; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency

1993
Constitutive choline transport in Pseudomonas aeruginosa.
    FEMS microbiology letters, 1998, May-01, Volume: 162, Issue:1

    Topics: Ammonium Chloride; Betaine; Biological Transport; Choline; Kinetics; Osmolar Concentration; Pseudomonas aeruginosa; Sarcosine; Sodium Chloride; Succinates

1998
Simple method for the routine determination of betaine and N,N-dimethylglycine in blood and urine.
    Clinical chemistry, 1998, Volume: 44, Issue:9

    Topics: Adult; Betaine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Humans; Infant; Middle Aged; Reference Values; Sarcosine; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1998
Exclusion and retention of compensatory kosmotropes by HPLC columns.
    Biochimica et biophysica acta, 1998, Sep-16, Volume: 1425, Issue:1

    Topics: Aluminum Oxide; Betaine; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Drug Stability; Glycine; Hydrogen Bonding; Ions; Models, Chemical; Osmolar Concentration; Polymers; Pressure; Proteins; Sarcosine; Silicon Dioxide; Solutions; Solvents; Taurine; Water

1998
Defect in dimethylglycine dehydrogenase, a new inborn error of metabolism: NMR spectroscopy study.
    Clinical chemistry, 1999, Volume: 45, Issue:4

    Topics: Adult; Dimethylglycine Dehydrogenase; Gas Chromatography-Mass Spectrometry; Humans; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Mitochondrial Proteins; Mutation, Missense; Odorants; Oxidoreductases, N-Demethylating; Sarcosine

1999
Non-growth-associated demethylation of dimethylsulfoniopropionate by (homo)acetogenic bacteria.
    Applied and environmental microbiology, 2001, Volume: 67, Issue:1

    Topics: Acetyl Coenzyme A; Betaine; Culture Media; Eubacterium; Genes, rRNA; Gram-Positive Rods; Methylation; Molecular Sequence Data; Phylogeny; Propionates; RNA, Ribosomal, 16S; Sarcosine; Sequence Analysis, DNA; Sulfonium Compounds

2001
Effect of dimethylglycine on gastric ulcers in rats.
    The Journal of pharmacy and pharmacology, 2000, Volume: 52, Issue:12

    Topics: Animals; Anti-Ulcer Agents; Dose-Response Relationship, Drug; Famotidine; Gastric Juice; Glutathione; Hydrogen-Ion Concentration; Ibuprofen; Ligation; Malondialdehyde; Pylorus; Rats; Rats, Wistar; Sarcosine; Severity of Illness Index; Stomach Ulcer; Stress, Physiological

2000
Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.
    American journal of human genetics, 2001, Volume: 68, Issue:4

    Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Black People; Blotting, Western; Cell Line; Chronic Disease; Cloning, Molecular; Creatine Kinase; Dimethylglycine Dehydrogenase; DNA Mutational Analysis; Expressed Sequence Tags; Fatigue; Humans; Magnetic Resonance Spectroscopy; Male; Metabolism, Inborn Errors; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Odorants; Oxidoreductases, N-Demethylating; Phenotype; Point Mutation; Sarcosine

2001
Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2001, Volume: 36, Issue:3

    Topics: Alcohols; Betaine; Esters; Imidazoles; Sarcosine; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization

2001
Conformation of cationic N,N-dimethylglycine in dimethylglycinium trifluoroacetate.
    Acta crystallographica. Section C, Crystal structure communications, 2001, Volume: 57, Issue:Pt 4

    Topics: Crystallography, X-Ray; Dietary Supplements; Molecular Conformation; Salts; Sarcosine; Trifluoroacetic Acid

2001
Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.
    Kidney international, 2001, Volume: 59, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Betaine; Betaine-Homocysteine S-Methyltransferase; Creatinine; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Kidney Failure, Chronic; Male; Methyltransferases; Middle Aged; Peritoneal Dialysis; Predictive Value of Tests; Pyridoxine; Renal Dialysis; Sarcosine; Uremia; Vitamin B 12; Zinc

2001
Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.
    Current microbiology, 2001, Volume: 43, Issue:2

    Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Choline; Chromatography, Agarose; Chromatography, Gel; Cyanobacteria; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Methyltransferases; Molecular Weight; Sarcosine

2001
Homocysteine metabolism in children with Down syndrome: in vitro modulation.
    American journal of human genetics, 2001, Volume: 69, Issue:1

    Topics: Adenosine; Case-Control Studies; Child; Chromatography, High Pressure Liquid; Cystathionine; Cystathionine beta-Synthase; Cysteine; DNA Methylation; Down Syndrome; Glutathione; Homocysteine; Humans; Leucovorin; Lymphocytes; Methionine; Oxidative Stress; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Superoxide Dismutase; Thymidine; Vitamin B 12

2001
Organization of the genes involved in dimethylglycine and sarcosine degradation in Arthrobacter spp.: implications for glycine betaine catabolism.
    European journal of biochemistry, 2001, Volume: 268, Issue:12

    Topics: Amino Acid Sequence; Arthrobacter; Betaine; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Genes, Bacterial; Molecular Sequence Data; Operon; Oxidoreductases Acting on CH-NH Group Donors; Recombinant Proteins; Sarcosine; Sequence Homology, Amino Acid

2001
Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition.
    Analytical biochemistry, 2001, Aug-15, Volume: 295, Issue:2

    Topics: Animals; Circadian Rhythm; Diestrus; Estrus; Female; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Metestrus; Methylamines; Rats; Rats, Sprague-Dawley; Sarcosine; Time Factors; Urine

2001
Mechanistic aspects of the covalent flavoprotein dimethylglycine oxidase of Arthrobacter globiformis studied by stopped-flow spectrophotometry.
    Biochemistry, 2002, Apr-09, Volume: 41, Issue:14

    Topics: Arthrobacter; Flavoproteins; Formaldehyde; Hydrogen Peroxide; Kinetics; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Sarcosine; Spectrophotometry

2002
Lysosomotropic N,N- dimethyl alpha-aminoacid N-alkyl esters and their quaternary ammonium salts as plasma membrane and mitochondrial ATPases inhibitors.
    Cellular & molecular biology letters, 2002, Volume: 7, Issue:4

    Topics: Adenosine Triphosphatases; Alanine; Cell Membrane; Mitochondria; Saccharomyces cerevisiae; Sarcosine

2002
Determination of choline, betaine, and dimethylglycine in plasma by a high-throughput method based on normal-phase chromatography-tandem mass spectrometry.
    Clinical chemistry, 2003, Volume: 49, Issue:2

    Topics: Adult; Aged; Betaine; Blood Donors; Choline; Chromatography, High Pressure Liquid; Fasting; Female; Humans; Male; Mass Spectrometry; Middle Aged; Sarcosine

2003
The isolation of formaldehyde from dimethylaminoethanol, dimethylglycine, sarcosine, and methanol.
    The Journal of biological chemistry, 1953, Volume: 203, Issue:2

    Topics: Alcohols; Amino Alcohols; Deanol; Ethanol; Fabaceae; Formaldehyde; Glycine; Liver; Methanol; Sarcosine

1953
The metabolism of dimethylglycine by liver mitochondria.
    The Journal of biological chemistry, 1958, Volume: 232, Issue:1

    Topics: Glycine; Humans; Liver; Mitochondria, Liver; Sarcosine

1958
N,N-dimethyl glycine-promoted Ullmann coupling reaction of phenols and aryl halides.
    Organic letters, 2003, Oct-16, Volume: 5, Issue:21

    Topics: Catalysis; Hydrocarbons, Halogenated; Models, Chemical; Molecular Structure; Phenols; Sarcosine

2003
A new class of potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: structure-activity relationships for a series of 9-alkoxymethyl-12-(3-hydroxypropyl)indeno[2,1-a]pyrrolo[3,4-c]carbazole-5-ones and the identification of CEP-521
    Journal of medicinal chemistry, 2003, Dec-04, Volume: 46, Issue:25

    Topics: Angiogenesis Inhibitors; Animals; Carbazoles; Cells, Cultured; Drug Screening Assays, Antitumor; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Female; Hemangiosarcoma; Humans; In Vitro Techniques; Indenes; Liver; Male; Mice; Mice, Nude; Models, Molecular; Phosphorylation; Prodrugs; Pyrroles; Rats; Rats, Sprague-Dawley; Sarcosine; Solubility; Structure-Activity Relationship; Vascular Endothelial Growth Factor Receptor-2

2003
Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.
    Biochemistry, 2004, May-11, Volume: 43, Issue:18

    Topics: Betaine; Betaine-Homocysteine S-Methyltransferase; Binding Sites; Catalysis; Enzyme Inhibitors; Glutamic Acid; Homocysteine; Humans; Kinetics; Ligands; Methionine; Methyltransferases; Mutagenesis, Site-Directed; Protein Binding; Sarcosine; Spectrometry, Fluorescence; Substrate Specificity; Tryptophan; Tyrosine

2004
Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase.
    Protein expression and purification, 2004, Volume: 37, Issue:2

    Topics: Animals; Biochemistry; Blotting, Western; Dimethylglycine Dehydrogenase; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrogen-Ion Concentration; Liver; Mitochondrial Proteins; Nickel; Oxidoreductases, N-Demethylating; Plasmids; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Recombinant Proteins; Sarcosine

2004
Betaine and folate status as cooperative determinants of plasma homocysteine in humans.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:2

    Topics: Adult; Aged; Betaine; Choline; Creatinine; Dose-Response Relationship, Drug; Fasting; Female; Folic Acid; Homocysteine; Humans; Male; Methionine; Middle Aged; Sarcosine; Vitamin B 12; Vitamin B 6

2005
Homocysteine, glycine betaine, and N,N-dimethylglycine in patients attending a lipid clinic.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Carnitine; Creatinine; Female; Homocysteine; Humans; Male; Middle Aged; Regression Analysis; Sarcosine; Sex Characteristics; Vascular Diseases

2005
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.
    Analytical chemistry, 2005, Mar-01, Volume: 77, Issue:5

    Topics: Amines; Animals; Biomarkers; Citric Acid; Creatine; Creatinine; Dietary Carbohydrates; Discriminant Analysis; Glyceric Acids; Hemiterpenes; Hippurates; Insulin Resistance; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Pentanoic Acids; Phenols; Principal Component Analysis; Propionates; Protons; Sarcosine; Succinic Acid; Taurine

2005
Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96.
    Biochemical and biophysical research communications, 2005, Jul-29, Volume: 333, Issue:2

    Topics: Binding Sites; Computer Simulation; Corynebacterium; Crystallography; Dimerization; Enzyme Activation; Leucovorin; Models, Chemical; Models, Molecular; Multiprotein Complexes; Oxidoreductases, N-Demethylating; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Sarcosine; Sarcosine Oxidase; Structure-Activity Relationship

2005
Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics.
    Analytical biochemistry, 2005, Aug-15, Volume: 343, Issue:2

    Topics: Animals; Biotransformation; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coumaric Acids; Factor Analysis, Statistical; Female; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Methylamines; Rats; Rats, Wistar; Sarcosine; Sex Characteristics; Urine

2005
Gas-phase structure of N,N-dimethylglycine.
    Chemphyschem : a European journal of chemical physics and physical chemistry, 2005, Aug-12, Volume: 6, Issue:8

    Topics: Gases; Hydrogen Bonding; Models, Chemical; Molecular Structure; Rotation; Sarcosine; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared

2005
Choline and homocysteine interrelations in umbilical cord and maternal plasma at delivery.
    The American journal of clinical nutrition, 2005, Volume: 82, Issue:4

    Topics: Betaine; Choline; Chromatography, Liquid; Creatinine; Cross-Sectional Studies; Female; Fetal Blood; Folic Acid; Health Status Indicators; Homocysteine; Humans; Infant, Newborn; Methylation; Oxidation-Reduction; Pregnancy; Regression Analysis; Sarcosine; Vitamin B 12

2005
Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.
    Journal of medicinal chemistry, 2006, Jun-15, Volume: 49, Issue:12

    Topics: Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Bronchoconstrictor Agents; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Drug Design; Guinea Pigs; Humans; Hypotension; Inositol Phosphates; Models, Molecular; Molecular Structure; Piperazine; Piperazines; Quinolines; Radioligand Assay; Receptor, Bradykinin B2; Sarcosine; Structure-Activity Relationship; Sulfonamides

2006
Mild and nonracemizing conditions for Ullmann-type diaryl ether formation between aryl iodides and tyrosine derivatives.
    The Journal of organic chemistry, 2006, Jul-07, Volume: 71, Issue:14

    Topics: Catalysis; Copper; Ethers; Hydrocarbons, Iodinated; Iodides; Molecular Structure; Sarcosine; Stereoisomerism; Tyrosine

2006
The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.
    Journal of cellular physiology, 2007, Volume: 210, Issue:1

    Topics: Alanine; Amino Acids; Animals; Betaine; Biological Transport; Blastocyst; Carrier Proteins; Chlorides; Dose-Response Relationship, Drug; Embryo Culture Techniques; Fallopian Tubes; Female; Kinetics; Mice; Proline; Sarcosine; Sodium; Time Factors; Water-Electrolyte Balance

2007
Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis.
    Research in microbiology, 2006, Volume: 157, Issue:10

    Topics: Betaine; Glycine; Glycine N-Methyltransferase; Methanosarcinaceae; Potassium Chloride; Sarcosine; Substrate Specificity

2006
Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:2

    Topics: Ketocholesterols; Sarcosine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:4

    Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Size; Cyclic Nucleotide-Regulated Protein Kinases; Gene Expression Regulation, Enzymologic; Liver Neoplasms; Osmolar Concentration; Osmosis; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Raffinose; Rats; RNA, Messenger; Saline Solution, Hypertonic; Sarcosine; Signal Transduction; Time Factors; Transcription, Genetic; Transfection; Urea; Water-Electrolyte Balance

2007
Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus.
    BMC complementary and alternative medicine, 2007, Jun-11, Volume: 7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Bone and Bones; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Immunosuppressive Agents; Mice; Perna; Rats; Sarcosine

2007
Sex differences in the control of plasma concentrations and urinary excretion of glycine betaine in patients attending a lipid disorders clinic.
    Clinical biochemistry, 2007, Volume: 40, Issue:16-17

    Topics: Adult; Betaine; Betaine-Homocysteine S-Methyltransferase; Carnitine; Female; Homocysteine; Humans; Lipid Metabolism Disorders; Male; Middle Aged; Sarcosine; Sex Factors; Thyroid Hormones

2007
Identification of two gene clusters and a transcriptional regulator required for Pseudomonas aeruginosa glycine betaine catabolism.
    Journal of bacteriology, 2008, Volume: 190, Issue:8

    Topics: Bacterial Proteins; Betaine; DNA Transposable Elements; Gene Deletion; Gene Expression Regulation, Bacterial; Gene Order; Genetic Complementation Test; Magnetic Resonance Spectroscopy; Metabolic Networks and Pathways; Multigene Family; Mutagenesis, Insertional; Pseudomonas aeruginosa; Sarcosine; Sarcosine Oxidase; Transcription Factors

2008
Relationship of dimethylglycine, choline, and betaine with oxoproline in plasma of pregnant women and their newborn infants.
    The Journal of nutrition, 2007, Volume: 137, Issue:12

    Topics: Adolescent; Adult; Betaine; Choline; Choline Dehydrogenase; Female; Gene Expression Regulation, Enzymologic; Glutathione; Glycine; Humans; Infant, Newborn; Middle Aged; Pregnancy; Pyrrolidonecarboxylic Acid; RNA, Messenger; Sarcosine

2007
Discovery of sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria.
    Proteins, 2009, Feb-01, Volume: 74, Issue:2

    Topics: Algal Proteins; Crystallography, X-Ray; Enzyme Stability; Kinetics; Methyltransferases; Protein Folding; Protein Structure, Tertiary; Rhodophyta; Sarcosine; Sequence Alignment; Substrate Specificity; Temperature

2009
Effect of poly(D, L-lactic acid) nanoparticles as triptolide carrier on abating rats renal toxicity by NMR-based metabolic analysis.
    Journal of nanoscience and nanotechnology, 2008, Volume: 8, Issue:7

    Topics: Animals; Diterpenes; Drug Carriers; Drug Delivery Systems; Epoxy Compounds; Kidney; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methylamines; Models, Chemical; Nanoparticles; Phenanthrenes; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Sarcosine; Time Factors

2008
GbdR regulates Pseudomonas aeruginosa plcH and pchP transcription in response to choline catabolites.
    Infection and immunity, 2009, Volume: 77, Issue:3

    Topics: Animals; AraC Transcription Factor; Betaine; Choline; DNA Mutational Analysis; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Male; Mice; Mice, Inbred C57BL; Phosphoric Monoester Hydrolases; Phosphorylcholine; Promoter Regions, Genetic; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; Sarcosine; Transcription, Genetic; Transferases (Other Substituted Phosphate Groups)

2009
Inter- and intra-individual variations of urinary endogenous metabolites in healthy male college students using (1)H NMR spectroscopy.
    Clinical chemistry and laboratory medicine, 2009, Volume: 47, Issue:2

    Topics: Adult; Analysis of Variance; Carboxylic Acids; Health; Humans; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Methylamines; Principal Component Analysis; Protons; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Taurine

2009
Effects of N, N-dimethylglycine on the development of in vitro produced bovine embryos.
    The Journal of reproduction and development, 2009, Volume: 55, Issue:3

    Topics: Animals; Cattle; Cells, Cultured; Cleavage Stage, Ovum; Embryo Culture Techniques; Embryo, Mammalian; Embryonic Development; Female; Fertilization in Vitro; Male; Sarcosine

2009
An internal reaction chamber in dimethylglycine oxidase provides efficient protection from exposure to toxic formaldehyde.
    The Journal of biological chemistry, 2009, Jun-26, Volume: 284, Issue:26

    Topics: Binding Sites; Catalysis; Catalytic Domain; Computer Simulation; Disinfectants; Escherichia coli; Formaldehyde; Green Fluorescent Proteins; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Sarcosine; Substrate Specificity

2009
Novel Tween 20 derivatives enable the formation of efficient pH-sensitive drug delivery vehicles for human hepatoblastoma.
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Drug Carriers; Glycine; Hepatoblastoma; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Polysorbates; Sarcosine; Surface-Active Agents; Tumor Cells, Cultured

2010
Linear and two-dimensional infrared spectroscopic study of the amide I and II modes in fully extended peptide chains.
    The journal of physical chemistry. B, 2011, May-12, Volume: 115, Issue:18

    Topics: Amides; Aminoisobutyric Acids; Hydrogen Bonding; Molecular Dynamics Simulation; Peptides; Sarcosine; Spectrophotometry, Infrared; Vibration

2011
Quantification of acetylcholine, choline, betaine, and dimethylglycine in human plasma and urine using stable-isotope dilution ultra performance liquid chromatography-tandem mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010, Dec-15, Volume: 878, Issue:32

    Topics: Acetylcholine; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Isotope Labeling; Linear Models; Male; Middle Aged; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Tandem Mass Spectrometry

2010
Local and bulk hydration of zwitterionic glycine and its analogues through molecular simulations.
    The journal of physical chemistry. B, 2011, Feb-03, Volume: 115, Issue:4

    Topics: Betaine; Glycine; Models, Chemical; Molecular Dynamics Simulation; Sarcosine; Water

2011
Effectiveness of nutritional supplements for reducing symptoms in autism-spectrum disorder: a case report.
    Journal of alternative and complementary medicine (New York, N.Y.), 2011, Volume: 17, Issue:3

    Topics: Autistic Disorder; Child; Child Behavior; Communication; Dietary Supplements; Humans; Interpersonal Relations; Magnesium; Male; Micronutrients; Sarcosine; Sensation; Treatment Outcome; Vitamin B 6

2011
A sensitive and specific LC-MS/MS method for rapid diagnosis of Niemann-Pick C1 disease from human plasma.
    Journal of lipid research, 2011, Volume: 52, Issue:7

    Topics: Adolescent; Adult; Calibration; Case-Control Studies; Child; Child, Preschool; Cholestanols; Chromatography, High Pressure Liquid; Female; Humans; Infant; Infant, Newborn; Ketocholesterols; Male; Middle Aged; Niemann-Pick Disease, Type C; Sarcosine; Sensitivity and Specificity; Tandem Mass Spectrometry; Time Factors; Young Adult

2011
Small-molecule inhibition of choline catabolism in Pseudomonas aeruginosa and other aerobic choline-catabolizing bacteria.
    Applied and environmental microbiology, 2011, Volume: 77, Issue:13

    Topics: Bacteria, Aerobic; Burkholderia; Carbon; Choline; Energy Metabolism; Enzyme Inhibitors; Metabolic Networks and Pathways; Nitrogen; Pseudomonas; Sarcosine; Sinorhizobium meliloti

2011
Betaine feeding prevents the blood alcohol cycle in rats fed alcohol continuously for 1 month using the rat intragastric tube feeding model.
    Experimental and molecular pathology, 2011, Volume: 91, Issue:2

    Topics: Alanine Transaminase; Animals; Betaine; Body Weight; Choline; Enteral Nutrition; Ethanol; Feeding Behavior; Gene Expression Regulation; Liver; Male; Models, Animal; Rats; Rats, Wistar; Sarcosine

2011
Plasma lipids and betaine are related in an acute coronary syndrome cohort.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Cohort Studies; Diabetes Complications; Dietary Supplements; Female; Humans; Hypolipidemic Agents; Lipids; Male; Middle Aged; Sarcosine

2011
Glycine and its N-methylated analogues cause pH-dependent membrane damage to enterotoxigenic Escherichia coli.
    Amino acids, 2012, Volume: 43, Issue:1

    Topics: Betaine; Cell Membrane; Emulsifying Agents; Enterotoxigenic Escherichia coli; Glycine; Hydrogen-Ion Concentration; N-substituted Glycines; Sarcosine

2012
Comprehensive solid-state NMR analysis reveals the effects of N-methylation on the molecular dynamics of glycine.
    The journal of physical chemistry. B, 2012, Jan-12, Volume: 116, Issue:1

    Topics: Betaine; Calorimetry, Differential Scanning; Carbon Isotopes; Glycine; Magnetic Resonance Spectroscopy; Methylation; Molecular Dynamics Simulation; Protons; Sarcosine; Temperature

2012
Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.
    Cardiovascular diabetology, 2012, Jul-11, Volume: 11

    Topics: Aged; Betaine; Biomarkers; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Glycosuria; Homocysteine; Humans; Linear Models; Male; Methionine; Middle Aged; New Zealand; Predictive Value of Tests; Reproducibility of Results; Sarcosine; Time Factors

2012
Betaine and secondary events in an acute coronary syndrome cohort.
    PloS one, 2012, Volume: 7, Issue:5

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Chromatography, High Pressure Liquid; Cohort Studies; Female; Heart Failure; Homocysteine; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Myocardial Infarction; New Zealand; Risk Factors; Sarcosine

2012
Effects of betaine supplementation and choline deficiency on folate deficiency-induced hyperhomocysteinemia in rats.
    Journal of nutritional science and vitaminology, 2012, Volume: 58, Issue:2

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Choline Deficiency; Dietary Supplements; Enzyme Inhibitors; Folic Acid; Folic Acid Deficiency; Homocysteine; Hyperhomocysteinemia; Liver; Male; Rats; Rats, Wistar; Sarcosine

2012
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Betaine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Choline; Cystathionine; Cysteine; Down Syndrome; Female; Glutathione; Humans; Infant; Male; Methionine; Methylation; Models, Theoretical; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Young Adult

2012
Plasma choline and betaine correlate with serum folate, plasma S-adenosyl-methionine and S-adenosyl-homocysteine in healthy volunteers.
    Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3

    Topics: Adolescent; Adult; Betaine; Choline; Chromatography, High Pressure Liquid; DNA Methylation; Female; Folic Acid; Gonadal Steroid Hormones; Humans; Linear Models; Male; Middle Aged; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Sex Factors; Tandem Mass Spectrometry; Young Adult

2013
Choline status and neurodevelopmental outcomes at 5 years of age in the Seychelles Child Development Nutrition Study.
    The British journal of nutrition, 2013, Jul-28, Volume: 110, Issue:2

    Topics: Betaine; Child Development; Child, Preschool; Choline; Cognition; Female; Homocysteine; Humans; Language; Linear Models; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Nutritional Status; Pregnancy; Sarcosine; Seychelles

2013
Elevated dimethylglycine in blood of children with congenital heart defects and their mothers.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:8

    Topics: Adult; Betaine; Betaine-Homocysteine S-Methyltransferase; Biomarkers; Child, Preschool; Choline; Chromatography, High Pressure Liquid; Female; Heart Defects, Congenital; Humans; Infant; Male; Mass Spectrometry; Mothers; Sarcosine; Socioeconomic Factors; Syria; Vitamin B 12 Deficiency

2013
Umbilical choline and related methylamines betaine and dimethylglycine in relation to birth weight.
    Pediatric research, 2013, Volume: 73, Issue:6

    Topics: Betaine; Birth Weight; Choline; Female; Humans; Infant, Newborn; Male; Pregnancy; Sarcosine; Umbilical Cord

2013
Exposure to the proton scavenger glycine under alkaline conditions induces Escherichia coli viability loss.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Adenosine Triphosphate; Alkalies; Betaine; Cell Membrane Permeability; Colony Count, Microbial; Escherichia coli; Esterases; Flow Cytometry; Fluorescence; Glycine; Homeostasis; Hydrogen-Ion Concentration; Indoles; Membrane Potentials; Microbial Sensitivity Tests; Microbial Viability; Phosphates; Protons; Sarcosine

2013
Effects of N,N-dimethylglycine sodium salt on apparent digestibility, vitamin E absorption, and serum proteins in broiler chickens fed a high- or low-fat diet.
    Poultry science, 2013, Volume: 92, Issue:5

    Topics: Absorption; Animal Nutritional Physiological Phenomena; Animals; Blood Proteins; Chickens; Diet, Fat-Restricted; Diet, High-Fat; Dietary Fats; Dietary Supplements; Digestion; Dose-Response Relationship, Drug; Male; Sarcosine; Vitamin E; Weight Gain

2013
DNA methylation potential: dietary intake and blood concentrations of one-carbon metabolites and cofactors in rural African women.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Betaine; Biomarkers; Choline; Cysteine; Diet; Diet Records; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; DNA Methylation; Feeding Behavior; Female; Folic Acid; Gambia; Homocysteine; Humans; Linear Models; Methionine; Middle Aged; Nutrition Assessment; Prospective Studies; Riboflavin; Rural Population; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine; Vitamin B 12; Vitamin B 6; Young Adult

2013
Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.
    The American journal of clinical nutrition, 2013, Volume: 97, Issue:6

    Topics: Adult; Betaine; Choline; Dietary Supplements; Fasting; Female; Folic Acid; Homocysteine; Humans; Longitudinal Studies; Nutritional Status; Pregnancy; Sarcosine; Spain; Vitamin B 12

2013
Methylation metabolites in amniotic fluid depend on gestational age.
    Prenatal diagnosis, 2013, Volume: 33, Issue:9

    Topics: Adult; Amniotic Fluid; Betaine; Choline; Female; Gestational Age; Humans; Methionine; Methylation; Methyltransferases; Pregnancy; Retrospective Studies; S-Adenosylhomocysteine; S-Adenosylmethionine; Sarcosine

2013
An inter-order horizontal gene transfer event enables the catabolism of compatible solutes by Colwellia psychrerythraea 34H.
    Extremophiles : life under extreme conditions, 2013, Volume: 17, Issue:4

    Topics: Adaptation, Physiological; Alteromonadaceae; Bacterial Proteins; Betaine; Choline; Evolution, Molecular; Gene Transfer, Horizontal; Genome, Bacterial; Methylation; Operon; Oxidation-Reduction; Phylogeny; Sarcosine; Sarcosine Oxidase

2013
Plasma dimethylglycine and risk of incident acute myocardial infarction in patients with stable angina pectoris.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:8

    Topics: Adult; Aged; Angina, Stable; Biomarkers; Energy Metabolism; Female; Follow-Up Studies; Humans; Incidence; Kaplan-Meier Estimate; Lipid Metabolism; Male; Middle Aged; Myocardial Infarction; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Factors; Sarcosine; Thrombosis

2013
Sarcosine and other metabolites along the choline oxidation pathway in relation to prostate cancer--a large nested case-control study within the JANUS cohort in Norway.
    International journal of cancer, 2014, Jan-01, Volume: 134, Issue:1

    Topics: Betaine; Biomarkers, Tumor; Case-Control Studies; Choline; Chromatography, Liquid; Cohort Studies; Glycine; Humans; Male; Mass Spectrometry; Middle Aged; Norway; Oxidation-Reduction; Prostatic Neoplasms; Sarcosine; Serine

2014
Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice.
    The Journal of nutrition, 2013, Volume: 143, Issue:10

    Topics: Age Factors; Aging; Animals; Bifidobacterium; Feces; Homocysteine; Intestines; Lactobacillus acidophilus; Magnetic Resonance Spectroscopy; Male; Metabolic Networks and Pathways; Metabolome; Mice; Mice, Inbred BALB C; NAD; Niacin; Niacinamide; Pentanoic Acids; Phenylacetates; Probiotics; Sarcosine; Xylose

2013
Low plasma vitamin B-12 is associated with a lower pregnancy-associated rise in plasma free choline in Canadian pregnant women and lower postnatal growth rates in their male infants.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:5

    Topics: Adult; Betaine; British Columbia; Child Development; Choline; Dietary Supplements; Female; Folic Acid; Humans; Infant; Male; Methionine; Middle Aged; Pregnancy; Prospective Studies; Sarcosine; Vitamin B 12; Vitamin B 12 Deficiency; Young Adult

2013
Characterization of the GbdR regulon in Pseudomonas aeruginosa.
    Journal of bacteriology, 2014, Volume: 196, Issue:1

    Topics: Betaine; Binding Sites; Choline; DNA, Bacterial; Gene Expression Regulation, Bacterial; Genes, Bacterial; Metabolic Networks and Pathways; Promoter Regions, Genetic; Protein Binding; Pseudomonas aeruginosa; Regulon; Sarcosine; Transcription Factors; Virulence

2014
Dimethylglycine provides salt and temperature stress protection to Bacillus subtilis.
    Applied and environmental microbiology, 2014, Volume: 80, Issue:9

    Topics: Bacillus subtilis; Betaine; Osmotic Pressure; Sarcosine; Sodium Chloride; Stress, Physiological; Temperature

2014
Elevated plasma dimethylglycine is a risk marker of mortality in patients with coronary heart disease.
    European journal of preventive cardiology, 2015, Volume: 22, Issue:6

    Topics: Angina, Stable; Betaine-Homocysteine S-Methyltransferase; Biomarkers; Genetic Predisposition to Disease; Humans; Linear Models; Logistic Models; Multivariate Analysis; Myocardial Infarction; Norway; Phenotype; Polymorphism, Single Nucleotide; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Sarcosine; Time Factors; Up-Regulation

2015
Measurement of concentrations of whole blood levels of choline, betaine, and dimethylglycine and their relations to plasma levels.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2014, Apr-15, Volume: 957

    Topics: Aged, 80 and over; Betaine; Choline; Chromatography, High Pressure Liquid; Female; Humans; Limit of Detection; Male; Reproducibility of Results; Sarcosine

2014
Plasma metabolite profiles of Alzheimer's disease and mild cognitive impairment.
    Journal of proteome research, 2014, May-02, Volume: 13, Issue:5

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Arachidonic Acid; Biomarkers; Chromatography, Liquid; Cognitive Dysfunction; Cytidine; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Thymine

2014
Plasma methionine, choline, betaine, and dimethylglycine in relation to colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:8

    Topics: Aged; Betaine; Case-Control Studies; Choline; Colorectal Neoplasms; Europe; Female; Humans; Male; Methionine; Middle Aged; Nutritional Status; Prospective Studies; Risk Factors; Sarcosine

2014
Folate in demethylation: the crystal structure of the rat dimethylglycine dehydrogenase complexed with tetrahydrofolate.
    Biochemical and biophysical research communications, 2014, Jul-11, Volume: 449, Issue:4

    Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Crystallization; Crystallography, X-Ray; Dimethylglycine Dehydrogenase; Humans; Kinetics; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Rats; Sarcosine; Tetrahydrofolates

2014
Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:4

    Topics: Acetylcarnitine; Adolescent; Adult; Africa, Western; Aged; Aged, 80 and over; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Case-Control Studies; Choline; Creatine; Female; Humans; Ketoglutaric Acids; Liver Neoplasms; Male; Methionine; Middle Aged; Niacinamide; Phenotype; Reproducibility of Results; Sarcosine; Sensitivity and Specificity; Young Adult

2014
Choline concentrations are lower in postnatal plasma of preterm infants than in cord plasma.
    European journal of nutrition, 2015, Volume: 54, Issue:5

    Topics: Adolescent; Adult; Betaine; Choline; Chromatography, Liquid; Enteral Nutrition; Female; Fetal Blood; Fetus; Glucocorticoids; Humans; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Male; Middle Aged; Parenteral Nutrition; Pregnancy; Premenopause; Prospective Studies; Sarcosine; Tandem Mass Spectrometry; Young Adult

2015
Copper/N,N-dimethylglycine catalyzed goldberg reactions between aryl bromides and amides, aryl iodides and secondary acyclic amides.
    Molecules (Basel, Switzerland), 2014, Aug-29, Volume: 19, Issue:9

    Topics: Catalysis; Chemistry Techniques, Synthetic; Copper; Formamides; Hydrocarbons, Brominated; Hydrocarbons, Iodinated; Sarcosine

2014
Plasma dimethylglycine, nicotine exposure and risk of low bone mineral density and hip fracture: the Hordaland Health Study.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2015, Volume: 26, Issue:5

    Topics: Absorptiometry, Photon; Aged; Bone Density; Female; Femur Neck; Hip Fractures; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Nicotine; Osteoporosis; Osteoporotic Fractures; Risk Factors; Sarcosine; Smoking

2015
Multipolar Ewald methods, 2: applications using a quantum mechanical force field.
    Journal of chemical theory and computation, 2015, Feb-10, Volume: 11, Issue:2

    Topics: Molecular Dynamics Simulation; Nitrophenols; Organophosphorus Compounds; Quantum Theory; Sarcosine; Water

2015
Dimethylglycine Deficiency and the Development of Diabetes.
    Diabetes, 2015, Volume: 64, Issue:8

    Topics: Aged; Alleles; Diabetes Mellitus, Type 2; Dimethylglycine Dehydrogenase; Female; Genome-Wide Association Study; Genotype; Humans; Insulin; Insulin Resistance; Male; Metabolome; Middle Aged; Sarcosine

2015
Maternal Choline Status, but Not Fetal Genotype, Influences Cord Plasma Choline Metabolite Concentrations.
    The Journal of nutrition, 2015, Volume: 145, Issue:7

    Topics: Adolescent; Adult; Betaine; Canada; Choline; Female; Fetal Blood; Fetus; Genotype; Healthy Volunteers; Humans; Maternal Nutritional Physiological Phenomena; Methylamines; Middle Aged; Polymorphism, Single Nucleotide; Pregnancy; Prospective Studies; Sarcosine; Surveys and Questionnaires; Young Adult

2015
A Protein Extract from Chicken Reduces Plasma Homocysteine in Rats.
    Nutrients, 2015, Jun-04, Volume: 7, Issue:6

    Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Caseins; Chickens; Choline; Cystathionine gamma-Lyase; Cysteine; Dietary Proteins; Folic Acid; Glycine; Homocysteine; Liver; Male; Meat; Methionine; Rats; Rats, Wistar; Riboflavin; RNA, Messenger; Sarcosine; Serine; Vitamin B 12; Vitamin B 6

2015
The impact of micronutrient supplementation in alcohol-exposed pregnancies on information processing skills in Ukrainian infants.
    Alcohol (Fayetteville, N.Y.), 2015, Volume: 49, Issue:7

    Topics: Adult; Central Nervous System Depressants; Choline; Dietary Supplements; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Heart Rate; Humans; Infant; Infant, Newborn; Learning; Mental Processes; Micronutrients; Neuropsychological Tests; Pregnancy; Prenatal Exposure Delayed Effects; Sarcosine; Socioeconomic Factors; Ukraine

2015
Peroxisome Proliferator-Activated Receptor Activation is Associated with Altered Plasma One-Carbon Metabolites and B-Vitamin Status in Rats.
    Nutrients, 2016, Jan-05, Volume: 8, Issue:1

    Topics: Animals; Antioxidants; Choline; Diet, High-Fat; Gene Expression; Liver; Male; Metabolic Networks and Pathways; Methylmalonic Acid; Niacinamide; Nicotinic Acids; One-Carbon Group Transferases; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR-beta; Pyridoxal; Random Allocation; Rats; Rats, Wistar; RNA, Messenger; Sarcosine; Sulfides; Vitamin B Complex

2016
N, N-Dimethylglycine decreases oxidative stress and improves in vitro development of bovine embryos.
    The Journal of reproduction and development, 2016, Apr-22, Volume: 62, Issue:2

    Topics: Animals; Antioxidants; Blastocyst; Cattle; Culture Media; Embryo Culture Techniques; Embryonic Development; Female; Fertilization in Vitro; Hydrogen Peroxide; Male; Ovarian Follicle; Oxidative Stress; Oxygen; Sarcosine; Zygote

2016
Assessment of Free Radical Scavenging Activity of Dimethylglycine Sodium Salt and Its Role in Providing Protection against Lipopolysaccharide-Induced Oxidative Stress in Mice.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Free Radical Scavengers; Lipopolysaccharides; Liver; Male; Malondialdehyde; Membrane Potential, Mitochondrial; Mice; Mitochondria, Liver; Organ Size; Oxidative Stress; Protective Agents; Protein Carbonylation; Reactive Oxygen Species; RNA, Messenger; Sarcosine

2016
N,N-dimethylglycine differentially modulates psychotomimetic and antidepressant-like effects of ketamine in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2016, 11-03, Volume: 71

    Topics: Acoustic Stimulation; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Exploratory Behavior; Fear; Hyperkinesis; Immobility Response, Tonic; Ketamine; Locomotion; Male; Memory Disorders; Mice; Mice, Inbred ICR; Prepulse Inhibition; Sarcosine

2016
Components of One-carbon Metabolism Other than Folate and Colorectal Cancer Risk.
    Epidemiology (Cambridge, Mass.), 2016, Volume: 27, Issue:6

    Topics: Aged; Amino Acids; Betaine; Biomarkers; Biomarkers, Tumor; Case-Control Studies; Choline; Colorectal Neoplasms; Female; Folic Acid; Follow-Up Studies; Humans; Logistic Models; Male; Methionine; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Protective Factors; Sarcosine; Sweden

2016
An isotope dilution capillary electrophoresis/tandem mass spectrometry (CE-MS/MS) method for the simultaneous measurement of choline, betaine, and dimethylglycine concentrations in human plasma.
    Analytical and bioanalytical chemistry, 2016, Volume: 408, Issue:26

    Topics: Aged; Betaine; Choline; Electrophoresis, Capillary; Female; Humans; Indicator Dilution Techniques; Isotope Labeling; Limit of Detection; Male; Middle Aged; Sarcosine; Tandem Mass Spectrometry

2016
Is N,N-dimethylglycine N-oxide a choline and betaine metabolite?
    Biological chemistry, 2017, 06-27, Volume: 398, Issue:7

    Topics: Adult; Betaine; Choline; Humans; Male; Metabolism, Inborn Errors; Methylamines; Sarcosine; Young Adult

2017
Comparison of Enzymatic Traits between Native and Recombinant Glycine Sarcosine N-Methyltransferase from Methanohalophilus portucalensis FDF1T.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Archaeal Proteins; Betaine; Escherichia coli; Glycine; Glycine N-Methyltransferase; Kinetics; Methanosarcinaceae; Protein Processing, Post-Translational; S-Adenosylhomocysteine; Sarcosine

2016
Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials.
    Journal of biomedical science, 2017, Feb-28, Volume: 24, Issue:1

    Topics: Animals; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine

2017
A Metabolic Study on the Biochemical Effects of Chiral Illegal Drugs in Rats Using
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2017, Volume: 137, Issue:9

    Topics: Animals; Citric Acid; Creatine; Creatinine; Dextromethorphan; Hippurates; Illicit Drugs; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Male; Metabolomics; Rats; Sarcosine; Stereoisomerism; Time Factors

2017
Glycine Betaine Monooxygenase, an Unusual Rieske-Type Oxygenase System, Catalyzes the Oxidative
    Applied and environmental microbiology, 2018, 07-01, Volume: 84, Issue:13

    Topics: Bacterial Proteins; Betaine; Catalysis; Chromohalobacter; Demethylation; Dinitrocresols; Edetic Acid; Escherichia coli; Gene Deletion; Kinetics; Metals; Mixed Function Oxygenases; Molecular Weight; Mutation; Open Reading Frames; Oxidation-Reduction; Oxidoreductases; Oxygenases; Sarcosine; Sequence Alignment; Sequence Analysis, Protein; Substrate Specificity

2018
In vitro free radical scavenging capacity of dimethylglycine sodium salt and its protective ability against oleic acid hydroperoxide-induced oxidative damage in IPEC-J2 cells.
    International journal of molecular medicine, 2018, Volume: 42, Issue:6

    Topics: Animals; Antioxidants; Cell Line; Erythrocytes; Free Radical Scavengers; Gene Expression Regulation; Hemolysis; Hydrogen Peroxide; Oleic Acid; Oxidative Stress; Protective Agents; Sarcosine; Swine

2018
Association between one-carbon metabolism indices and DNA methylation status in maternal and cord blood.
    Scientific reports, 2018, 11-15, Volume: 8, Issue:1

    Topics: Adult; Carbon; CpG Islands; DNA Methylation; Female; Fetal Blood; Humans; Metabolome; Pregnancy; Sarcosine; Young Adult

2018
Dimethylglycine sodium salt protects against oxidative damage and mitochondrial dysfunction in the small intestines of mice.
    International journal of molecular medicine, 2019, Volume: 43, Issue:5

    Topics: Animals; Antioxidants; Gene Expression Regulation; Indomethacin; Intestine, Small; Male; Mice; Mitochondria; Oxidation-Reduction; Oxidative Stress; Protective Agents; Sarcosine

2019
Maternal betaine status, but not that of choline or methionine, is inversely associated with infant birth weight.
    The British journal of nutrition, 2019, Volume: 121, Issue:11

    Topics: Adult; Betaine; Birth Weight; Choline; Female; Homocysteine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Male; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Pregnancy Trimesters; Sarcosine

2019
Serum Betaine and Dimethylglycine Are Higher in South Asian Compared with European Pregnant Women in Canada, with Betaine and Total Homocysteine Inversely Associated in Early and Midpregnancy, Independent of Ethnicity.
    The Journal of nutrition, 2019, 12-01, Volume: 149, Issue:12

    Topics: Adult; Betaine; Canada; Ethnicity; Europe; Female; Homocysteine; Humans; India; Pregnancy; Retrospective Studies; Sarcosine

2019
High concentrations of trimethylamines in slime glands inhibit skein unraveling in Pacific hagfish.
    The Journal of experimental biology, 2019, 11-22, Volume: 222, Issue:Pt 22

    Topics: Adhesives; Animals; Betaine; Hagfishes; Methylamines; Mucus; Sarcosine; Seawater

2019
Exploring the Scope of Tandem Palladium and Isothiourea Relay Catalysis for the Synthesis of α-Amino Acid Derivatives.
    Molecules (Basel, Switzerland), 2020, May-25, Volume: 25, Issue:10

    Topics: Amino Acids; Catalysis; Chemistry Techniques, Synthetic; Esters; Humans; Mesylates; Palladium; Phosphates; Quaternary Ammonium Compounds; Sarcosine; Stereoisomerism; Tetramisole; Thiourea

2020
Role of
    Applied and environmental microbiology, 2020, 08-18, Volume: 86, Issue:17

    Topics: Chromohalobacter; Genes, Bacterial; Genetic Complementation Test; Sarcosine

2020
Comprehensive metabolomic analysis of first-trimester serum identifies biomarkers of early-onset hypertensive disorder of pregnancy.
    Scientific reports, 2020, 08-17, Volume: 10, Issue:1

    Topics: Biomarkers; Cysteine; Early Diagnosis; Electrophoresis, Capillary; Female; Humans; Hypertension, Pregnancy-Induced; Mass Spectrometry; Metabolomics; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Propensity Score; Sarcosine

2020
Investigations of Dimethylglycine, Glycine Betaine, and Ectoine Uptake by a Betaine-Carnitine-Choline Transporter Family Transporter with Diverse Substrate Specificity in
    Journal of bacteriology, 2020, 11-19, Volume: 202, Issue:24

    Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids, Diamino; Bacterial Proteins; Betaine; Biological Transport; Carnitine; Choline; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Multigene Family; Sarcosine; Vibrio parahaemolyticus

2020
N,N-dimethylglycine prevents toluene-induced impairment in recognition memory and synaptic plasticity in mice.
    Toxicology, 2020, 12-15, Volume: 446

    Topics: Animals; Dose-Response Relationship, Drug; Exploratory Behavior; Male; Memory Disorders; Mice; Mice, Inbred ICR; Neuronal Plasticity; Recognition, Psychology; Sarcosine; Solvents; Toluene

2020
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
    Clinical chemistry, 2021, 01-08, Volume: 67, Issue:1

    Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; Humans; Male; Methylamines; Prospective Studies; Risk Factors; Sarcosine

2021
The expression levels of plasma dimethylglycine (DMG), human maternally expressed gene 3 (MEG3), and Apelin-12 in patients with acute myocardial infarction and their clinical significance.
    Annals of palliative medicine, 2021, Volume: 10, Issue:2

    Topics: Biomarkers; Humans; Intercellular Signaling Peptides and Proteins; Male; Myocardial Infarction; RNA, Long Noncoding; Sarcosine

2021
Integrated metabolomic analysis and cytokine profiling define clusters of immuno-metabolic correlation in new-onset psoriasis.
    Scientific reports, 2021, 05-18, Volume: 11, Issue:1

    Topics: Case-Control Studies; Cytokines; Humans; Inflammation Mediators; Isoleucine; Magnetic Resonance Spectroscopy; Metabolomics; Sarcosine; Skin

2021
Associations of circulating choline and its related metabolites with cardiometabolic biomarkers: an international pooled analysis.
    The American journal of clinical nutrition, 2021, 09-01, Volume: 114, Issue:3

    Topics: Betaine; Biomarkers; Cardiovascular Diseases; Carnitine; Choline; Creatinine; Cross-Sectional Studies; Diet; Humans; Sarcosine

2021
Effect of
    Biomedical and environmental sciences : BES, 2021, May-20, Volume: 34, Issue:5

    Topics: Animals; Biomarkers; Chromatography, Liquid; Diet; Dietary Supplements; Folic Acid Deficiency; Homocysteine; Liver; Male; Random Allocation; Rats; Rats, Wistar; Sarcosine

2021
Dietary dimethylglycine sodium salt supplementation improves growth performance, redox status, and skeletal muscle function of intrauterine growth-restricted weaned piglets.
    Journal of animal science, 2021, Jul-01, Volume: 99, Issue:7

    Topics: Animals; Dietary Supplements; DNA, Mitochondrial; Female; Fetal Growth Retardation; Muscle, Skeletal; Oxidation-Reduction; Sarcosine; Sodium; Swine; Swine Diseases; Weaning

2021
N, N-dimethylglycine Protects Behavioral Disturbances and Synaptic Deficits Induced by Repeated Ketamine Exposure in Mice.
    Neuroscience, 2021, 09-15, Volume: 472

    Topics: Animals; Ketamine; Long-Term Potentiation; Male; Mice; Mice, Inbred ICR; Receptors, N-Methyl-D-Aspartate; Sarcosine

2021
Effects of dietary dimethylglycine supplementation on laying performance, egg quality, and tissue index of hens during late laying period.
    Poultry science, 2022, Volume: 101, Issue:2

    Topics: Animal Feed; Animals; Chickens; Diet; Dietary Supplements; Egg Yolk; Female; Ovum; Sarcosine

2022
The metabolomic profiling identifies N, N-dimethylglycine as a facilitator of dorsal root ganglia neuron axon regeneration after injury.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:5

    Topics: Axons; Ganglia, Spinal; Metabolomics; Nerve Regeneration; Neurons; Sarcosine

2022
Dimethylglycine sodium salt activates Nrf2/SIRT1/PGC1α leading to the recovery of muscle stem cell dysfunction in newborns with intrauterine growth restriction.
    Free radical biology & medicine, 2022, 05-01, Volume: 184

    Topics: Animals; Animals, Newborn; Antioxidants; Fetal Growth Retardation; Muscle, Skeletal; Myoblasts; NF-E2-Related Factor 2; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sarcosine; Sirtuin 1; Sodium; Stem Cells; Swine

2022
Heat stress-induced intestinal barrier damage and dimethylglycine alleviates via improving the metabolism function of microbiota gut brain axis.
    Ecotoxicology and environmental safety, 2022, Oct-01, Volume: 244

    Topics: Animals; Brain-Gut Axis; Chickens; Choline; Fatty Acids, Volatile; Heat-Shock Response; Humans; Interleukin-10; Interleukin-6; Isobutyrates; Microbiota; Neurotransmitter Agents; NF-kappa B; Sarcosine; Serotonin; Tryptophan

2022