dimethylarsinous acid has been researched along with cacodylic acid in 71 studies
| Studies (dimethylarsinous acid) | Trials (dimethylarsinous acid) | Recent Studies (post-2010) (dimethylarsinous acid) | Studies (cacodylic acid) | Trials (cacodylic acid) | Recent Studies (post-2010) (cacodylic acid) |
|---|---|---|---|---|---|
| 72 | 1 | 34 | 786 | 5 | 339 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 36 (50.70) | 29.6817 |
| 2010's | 33 (46.48) | 24.3611 |
| 2020's | 2 (2.82) | 2.80 |
| Authors | Studies |
|---|---|
| Arnold, LL; Cano, M; Cohen, SM; Le, XC; Lu, X; St John, M; Uzvolgyi, E; Yamamoto, S | 1 |
| Cullen, WR; Kadiiska, M; Lambert, G; Mason, RP; Mass, MJ; Nesnow, S; Roop, BC | 1 |
| Cullen, WR; Gong, Z; Jiang, G; Le, XC; Li, XF | 1 |
| Date, Y; Endo, G; Fukushima, S; Inoue, Y; Kuroda, K; Wanibuchi, H; Yoshida, K; Zhou, X | 1 |
| Arnold, LL; Cohen, SM; Cullen, WR; Le, XC; Lu, X | 1 |
| Gong, Z; Le, XC; Lu, X; Wang, Z; Zhou, J | 1 |
| Feldmann, J; Hansen, HR; Jaspars, M; Milne, BF; Raab, A | 1 |
| Arnold, LL; Cohen, SM; Cullen, WR; Le, XC; Li, XF; Lu, M; Lu, X; Wang, H | 1 |
| Borja-Aburto, VH; Calderon-Aranda, ES; Cruz-Gonzalez, MB; Del Razo, LM; Garcia-Montalvo, EA; Garcia-Vargas, GG; Valenzuela, OL | 1 |
| Dopp, E; Florea, AM; Hartmann, LM; Hirner, AV; Rabieh, S; Rettenmeier, AW; Shokouhi, B; von Recklinghausen, U; Yadav, S; Zimmermann, U | 1 |
| An, Y; Kato, K; Mizoi, M; Nakano, M; Okada, S; Sagesaka, Y; Takabayashi, F; Yamanaka, K | 1 |
| Cheng, YM; Ho, IC; Hu, YJ; Lee, TC; Su, PF | 1 |
| Naranmandura, H; Suzuki, KT; Suzuki, N | 1 |
| Himeno, S; Hirano, S; Kobayashi, Y; Kojima, C; Sakurai, MH; Sakurai, T; Waalkes, MP | 1 |
| Arnold, LL; Cohen, SM; Le, XC; Ohnishi, T | 1 |
| Gurr, JR; Jan, KY; Wang, AS; Wang, TC | 1 |
| Arnold, LL; Cohen, SM; Le, XC; Li, XF; Lu, M; Wang, H | 1 |
| Hickey, C; Klein, CB; Leszczynska, J; Rossman, TG | 1 |
| Kita, K; Ochi, T; Suzuki, T | 1 |
| Chen, YC; Christiani, DC; Hsueh, YM; Mahiuddin, G; McCarty, KM; Quamruzzaman, Q; Rahman, M; Ryan, L; Smith, T; Su, L | 1 |
| Clewell, HJ; Crump, KS; El-Masri, HA; Gentry, PR; Kenyon, EM; Thomas, RS; Yager, JW | 1 |
| Binding, N; Hartmann, LM; Hippler, J; Hirner, AV; Krüger, K; Musshoff, U; Repges, H; Straub, H | 1 |
| Anzai, K; Mandal, BK; Suzuki, KT | 1 |
| Naranmandura, H; Suzuki, KT | 2 |
| Le, XC; Li, XF; Lu, M; Wang, H; Wang, Z | 1 |
| Adair, BM; Clewell, HJ; Crecelius, EA; Highfill, JH; Hughes, MF; Kenyon, EM; Yager, JW | 1 |
| Elizondo, G; Estrada-Muñiz, E; Medina-Díaz, IM; Ramírez, P; Reyes-Hernández, OD; Vega, L | 1 |
| Cullen, WR; Le, XC; Lee, J; Shen, S; Weinfeld, M | 1 |
| Bae, ON; Chung, JH; Chung, SM; Kim, SH; Lim, KM; Noh, JY | 1 |
| Endo, G; Kitamura, M; Kuroda, K | 1 |
| Binding, N; Hippler, J; Hirner, AV; Krüger, K; Musshoff, U; Straub, H | 1 |
| Arnold, LL; Cohen, SM; Kakiuchi-Kiyota, S; Pennington, KL; Suzuki, S | 1 |
| Arnold, LL; Chen, B; Cohen, SM; Le, XC; Pennington, KL; Suzuki, S | 1 |
| An, Y; Li, Z; Wang, S; Wang, Z | 1 |
| Kita, K; Miyazaki, K; Ochi, T; Suzuki, T | 1 |
| Iwata, K; Naranmandura, H; Ogra, Y; Suzuki, KT | 1 |
| Basu, A; Bates, MN; Hubbard, AE; Kalman, D; Porter, KE; Rey, O; Skibola, CF; Smith, A; Smith, MT; Steinmaus, C | 1 |
| Kligerman, AD; Tennant, AH | 1 |
| Currier, JM; de Moraes, DP; Dĕdina, J; Matousek, T; Stýblo, M; Svoboda, M | 1 |
| Calatayud, M; Devesa, V; Montoro, R; Vélez, D | 1 |
| Bu, N; Hao, WH; Liu, H; Lou, YJ; Naranmandura, H; Ogra, Y; Sawata, T; Suzuki, N; Xu, S | 1 |
| Castellanos, EH; Currier, JM; Del Razo, LM; Drobná, Z; García-Vargas, GG; Loomis, D; Sánchez-Peña, LC; Stýblo, M; Valenzuela, OL | 1 |
| Marapakala, K; Qin, J; Rosen, BP | 1 |
| Bornhorst, J; Ebert, F; Humpf, HU; Karst, U; Lohren, H; Schwerdtle, T | 1 |
| Chen, SQ; Chen, X; Chen, Z; Naranmandura, H; Rehman, K; Suzuki, N; Tanaka, M; Wang, WW; Xu, S | 1 |
| Chen, Z; Naranmandura, H; Rehman, K; Sakamoto, A; Suzuki, N; Wang, WW; Wang, YW; Zhang, YF | 1 |
| Arnold, LL; Cohen, SM; Dodmane, PR; Pennington, KL; Thomas, DJ | 1 |
| Gregus, Z; Németi, B | 1 |
| Arnold, LL; Cohen, SM; Dave, BJ; Dodmane, PR; Le, XC; Lu, X; Muirhead, DE; Pennington, KL; Suzuki, S; Yokohira, M | 1 |
| Calatayud, M; Devesa, V; Gimeno-Alcañiz, JV; Vélez, D | 2 |
| Chen, C; Dong, Z; Li, B; Li, H; Li, Y; Lin, J; Yan, J; Zhang, W | 1 |
| Rockenbauer, A; Villamena, FA; Zamora, PL | 1 |
| Bhowmick, S; Chatterjee, D; Guha Mazumder, DN; Halder, D; Iglesias, M; Nriagu, J; Roman-Ross, G | 1 |
| Banerjee, M; Carew, MW; Le, XC; Leslie, EM; Naranmandura, H; Roggenbeck, BA; Whitlock, BD | 1 |
| Fu, YJ; Naranmandura, H; Rehman, K; Sun, TF; Sun, WH; Wang, QQ; Wu, B; Wu, Y; Zhang, YF; Zhou, XY | 1 |
| Bao, LL; Jin, HF; Li, CH; Naranmandura, H; Qin, YJ; Wang, WW; Zhang, M | 1 |
| Jiang, YH; Lan, YF; Maimaitiyiming, Y; Naranmandura, H; Rehman, K; Wang, QQ; Zhu, DY | 1 |
| Geng, Z; Li, X; Shi, N; Wang, S; Wang, Z | 1 |
| Endo, G; Endo, Y; Kato, K; Kurosawa, H; Shimoda, Y; Yamanaka, K | 1 |
| Bain, LJ; Brumaghim, JL; Liu, JT; McCoy, CR; Stadelman, BS | 1 |
| Bu, N; Cao, FL; Naranmandura, H; Wang, QQ; Zhang, YF; Zhou, J; Zhou, XY | 1 |
| Cui, N; Gao, J; Guo, Z; Li, H; Wei, B; Wu, K; Xia, Y; Yang, L; Yu, J | 1 |
| Garcia-Algar, O; Guzman, C; Joya, X; Marcos, S; Piñol, S; Puig, C; Sala, A; Vall, O; Velasco, M; Velez, D | 1 |
| Chen, B; Chen, LWL; Gabos, S; Le, XC; Li, XF; Lu, X; Moe, B; Peng, H | 1 |
| Kong, C; Li, H; Wang, J; Wei, B; Wu, K; Xia, Y; Yang, L; Yu, J | 1 |
| Cai, Y; McCord, B; McGoron, AJ; Mebel, A; Sun, Y; Yang, M; Zhang, X | 1 |
| Bilinsky, LM; Fisher, JW; Thomas, DJ | 1 |
| Chen, B; Huang, Z; Li, S; Song, F; Wang, J; Yang, C; Zhang, J | 1 |
| Fry, RC; Stýblo, M; Thomas, DJ; Venkatratnam, A | 1 |
2 review(s) available for dimethylarsinous acid and cacodylic acid
| Article | Year |
|---|---|
Arsenic-induced bladder cancer in an animal model.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Carcinogens; Disease Models, Animal; Hemoglobins; Mice; Oxidative Stress; Protein Binding; Rats; Sulfhydryl Compounds; Urinary Bladder Neoplasms | 2007 |
Origins, fate, and actions of methylated trivalent metabolites of inorganic arsenic: progress and prospects.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Cells, Cultured; Humans; Methylation; Methyltransferases; Oxidation-Reduction | 2021 |
1 trial(s) available for dimethylarsinous acid and cacodylic acid
| Article | Year |
|---|---|
Arsenic speciation in urine from acute promyelocytic leukemia patients undergoing arsenic trioxide treatment.
Topics: Adult; Antineoplastic Agents; Arsenic; Arsenic Trioxide; Arsenicals; Arsenites; Cacodylic Acid; Chromatography, High Pressure Liquid; Humans; Injections, Intravenous; Leukemia, Promyelocytic, Acute; Male; Methylation; Middle Aged; Oxidation-Reduction; Oxides | 2004 |
68 other study(ies) available for dimethylarsinous acid and cacodylic acid
| Article | Year |
|---|---|
Possible role of dimethylarsinous acid in dimethylarsinic acid-induced urothelial toxicity and regeneration in the rat.
Topics: Animals; Body Weight; Cacodylic Acid; Carcinogens; Cells, Cultured; Female; Humans; Lethal Dose 50; Microscopy, Electron, Scanning; Rats; Rats, Inbred F344; Regeneration; Time Factors; Urinary Bladder; Urothelium | 2002 |
DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species.
Topics: Arsenic; Bacteriophage phi X 174; Cacodylic Acid; Cyclic N-Oxides; DNA Damage; DNA Methylation; DNA, Superhelical; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Humans; In Situ Nick-End Labeling; Organometallic Compounds; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2002 |
Interaction of trivalent arsenicals with metallothionein.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Chromatography, High Pressure Liquid; Metallothionein; Organometallic Compounds; Spectrometry, Mass, Electrospray Ionization | 2003 |
Urinary sulfur-containing metabolite produced by intestinal bacteria following oral administration of dimethylarsinic acid to rats.
Topics: Administration, Oral; Animals; Arsenicals; Cacodylic Acid; Chromatography, High Pressure Liquid; Cysteine; Escherichia coli; Exotoxins; Female; HL-60 Cells; Humans; Hydrogen Peroxide; Intestinal Mucosa; Intestines; Rats; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds; Superoxide Dismutase | 2003 |
Speciation of dimethylarsinous acid and trimethylarsine oxide in urine from rats fed with dimethylarsinic acid and dimercaptopropane sulfonate.
Topics: Administration, Oral; Animals; Arsenicals; Cacodylic Acid; Dimercaprol; Female; Propane; Rats; Rats, Inbred F344 | 2003 |
Sulfur-containing arsenical mistaken for dimethylarsinous acid [DMA(III)] and identified as a natural metabolite in urine: major implications for studies on arsenic metabolism and toxicity.
Topics: Animals; Arsenic Poisoning; Arsenicals; Cacodylic Acid; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Sheep; Spectrometry, Mass, Electrospray Ionization; Sulfur Compounds; Wool | 2004 |
Evidence of hemoglobin binding to arsenic as a basis for the accumulation of arsenic in rat blood.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Female; Hemoglobins; Humans; Organometallic Compounds; Rats | 2004 |
Urinary trivalent methylated arsenic species in a population chronically exposed to inorganic arsenic.
Topics: Adolescent; Adult; Arsenic Poisoning; Arsenicals; Cacodylic Acid; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Male; Methylation; Mexico; Middle Aged; Neoplasms; Risk Assessment; Water Supply | 2005 |
Forced uptake of trivalent and pentavalent methylated and inorganic arsenic and its cyto-/genotoxicity in fibroblasts and hepatoma cells.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Carcinoma, Hepatocellular; Cell Cycle; Cell Nucleus; Cell Survival; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Electroporation; Fibroblasts; Humans; Micronucleus Tests; Organometallic Compounds | 2005 |
The role of trivalent dimethylated arsenic in dimethylarsinic acid-promoted skin and lung tumorigenesis in mice: tumor-promoting action through the induction of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenoma; Administration, Topical; Animals; Cacodylic Acid; Carcinogenicity Tests; Carcinogens; Deoxyguanosine; Female; Herbicides; Lung Neoplasms; Male; Mice; Mice, Hairless; Oxidative Stress; Skin Neoplasms | 2005 |
Distinct gene expression profiles in immortalized human urothelial cells exposed to inorganic arsenite and its methylated trivalent metabolites.
Topics: Arsenites; Cacodylic Acid; Cell Line; Cell Line, Tumor; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Humans; Interleukin-1; NF-kappa B; Oligonucleotide Array Sequence Analysis; Organometallic Compounds; Urethra | 2006 |
Trivalent arsenicals are bound to proteins during reductive methylation.
Topics: Animals; Arsenites; Cacodylic Acid; Chromatography, High Pressure Liquid; Kidney; Liver; Male; Mass Spectrometry; Methylation; Molecular Weight; Oxidation-Reduction; Protein Binding; Protein Denaturation; Proteins; Rats; Rats, Wistar; Tissue Distribution | 2006 |
Toxicity of a trivalent organic arsenic compound, dimethylarsinous glutathione in a rat liver cell line (TRL 1215).
Topics: Animals; Antineoplastic Agents; Arsenic Poisoning; Arsenicals; Arsenites; Cacodylic Acid; Cell Line; Cell Survival; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Erythrocytes; Glutathione; Hepatocytes; Humans; Inhibitory Concentration 50; Methylation; Rats; Rats, Inbred F344; Serum Albumin; Time Factors | 2006 |
Trivalent arsenicals induce lipid peroxidation, protein carbonylation, and oxidative DNA damage in human urothelial cells.
Topics: Arsenic Poisoning; Arsenicals; Cacodylic Acid; Cell Line; DNA Damage; Glutathione; Humans; Lipid Peroxidation; Oxidation-Reduction; Protein Carbonylation; Urinary Bladder Neoplasms; Urothelium; Water Pollutants, Chemical | 2007 |
Binding of dimethylarsinous acid to cys-13alpha of rat hemoglobin is responsible for the retention of arsenic in rat blood.
Topics: Amino Acid Sequence; Animals; Arsenic; Binding Sites; Cacodylic Acid; Chromatography, Gel; Chromatography, High Pressure Liquid; Cysteine; Female; Hemoglobins; Rats; Rats, Inbred F344; Spectrometry, Mass, Electrospray Ionization | 2007 |
Further evidence against a direct genotoxic mode of action for arsenic-induced cancer.
Topics: Animals; Cacodylic Acid; Carcinogens; Cell Line, Tumor; Cell Survival; CHO Cells; Clone Cells; Cricetinae; Cricetulus; Humans; Mice; Mice, Hairless; Mutagens; Neoplasms; Organometallic Compounds; Reverse Transcriptase Polymerase Chain Reaction | 2007 |
Down-regulation of glutaminase C in human hepatocarcinoma cell by diphenylarsinic acid, a degradation product of chemical warfare agents.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Arsenicals; Arsenites; Cacodylic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Chaperonin Containing TCP-1; Chaperonins; Chemical Warfare Agents; Dose-Response Relationship, Drug; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Glutaminase; HeLa Cells; Humans; Immunoblotting; Isoenzymes; Retinal Dehydrogenase; Ribosomal Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors | 2007 |
Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions.
Topics: Adult; Arsenates; Arsenic; Arsenicals; Arsenites; Bangladesh; Cacodylic Acid; Case-Control Studies; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Male; Methylation; Nails; Polymorphism, Genetic; Skin Diseases; Water Pollutants, Chemical; Water Supply | 2007 |
Research toward the development of a biologically based dose response assessment for inorganic arsenic carcinogenicity: a progress report.
Topics: Animals; Arsenic; Arsenicals; Cacodylic Acid; Carcinogens; Cell Proliferation; DNA; DNA Repair; Dose-Response Relationship, Drug; Mice; Nonlinear Dynamics; Oligonucleotide Array Sequence Analysis; Oxidative Stress; Poisons; Signal Transduction; Tissue Distribution; Urinary Bladder Neoplasms | 2007 |
Effects of dimethylarsinic and dimethylarsinous acid on evoked synaptic potentials in hippocampal slices of young and adult rats.
Topics: Age Factors; Animals; Arsenic Poisoning; Cacodylic Acid; Dose-Response Relationship, Drug; Environmental Pollutants; Evoked Potentials; Excitatory Postsynaptic Potentials; Hippocampus; Long-Term Potentiation; Rats; Rats, Wistar | 2007 |
Impact of arsenic in foodstuffs on the people living in the arsenic-affected areas of West Bengal, India.
Topics: Arsenic; Arsenic Poisoning; Arsenicals; Arsenites; Cacodylic Acid; Chromatography, High Pressure Liquid; Environmental Monitoring; Erythrocytes; Humans; India; Mass Spectrometry; Oryza | 2007 |
Formation of dimethylthioarsenicals in red blood cells.
Topics: Animals; Biological Transport; Cacodylic Acid; Coculture Techniques; Culture Media; Erythrocytes; Hepatocytes; Humans; Male; Rats; Rats, Wistar | 2008 |
Identification of the major arsenic-binding protein in rat plasma as the ternary dimethylarsinous-hemoglobin-haptoglobin complex.
Topics: Amino Acid Sequence; Animals; Arsenic; Blood Proteins; Cacodylic Acid; Chromatography, Gel; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Haptoglobins; Hemoglobins; Indicators and Reagents; Male; Mass Spectrometry; Molecular Sequence Data; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Trypsin | 2008 |
Identification of reactive cysteines in a protein using arsenic labeling and collision-induced dissociation tandem mass spectrometry.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cacodylic Acid; Cysteine; Erythrocytes; Glutathione; Hemoglobins; Molecular Sequence Data; Protein Binding; Rats; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2008 |
Tissue distribution and urinary excretion of inorganic arsenic and its methylated metabolites in C57BL6 mice following subchronic exposure to arsenate in drinking water.
Topics: Animals; Arsenates; Arsenic; Arsenicals; Cacodylic Acid; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Tissue Distribution | 2008 |
Arsenite and its metabolites, MMA(III) and DMA(III), modify CYP3A4, PXR and RXR alpha expression in the small intestine of CYP3A4 transgenic mice.
Topics: Animals; Arsenites; Blotting, Western; Cacodylic Acid; Cytochrome P-450 CYP3A; Duodenum; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; Organometallic Compounds; Pregnane X Receptor; Proteasome Endopeptidase Complex; Receptors, Steroid; Retinoid X Receptor alpha; Reverse Transcriptase Polymerase Chain Reaction; Sodium Compounds; Ubiquitin | 2009 |
Arsenite and its mono- and dimethylated trivalent metabolites enhance the formation of benzo[a]pyrene diol epoxide-DNA adducts in Xeroderma pigmentosum complementation group A cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Arsenites; Cacodylic Acid; Cell Line; Cell Line, Transformed; DNA Adducts; DNA Damage; DNA Repair; Electrophoresis, Capillary; Fibroblasts; Glutathione Transferase; Humans; Organometallic Compounds; Time Factors; Xeroderma Pigmentosum Group A Protein | 2009 |
Trivalent methylated arsenical-induced phosphatidylserine exposure and apoptosis in platelets may lead to increased thrombus formation.
Topics: Adolescent; Adult; Animals; Apoptosis; Blood Coagulation; Blood Platelets; Cacodylic Acid; Calcium; Caspase 3; Cells, Cultured; Cytochromes c; Disease Models, Animal; Humans; Male; Membrane Potential, Mitochondrial; Organometallic Compounds; Phosphatidylserines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfhydryl Compounds; Venous Thrombosis; Young Adult | 2009 |
Dimethylarsinous acid disturbs cytokinesis.
Topics: Animals; Cacodylic Acid; Cell Division; Cell Line; Cricetinae; Cytokinesis; Polyploidy | 2009 |
Effects of monomethylarsonic and monomethylarsonous acid on evoked synaptic potentials in hippocampal slices of adult and young rats.
Topics: Age Factors; Animals; Arsenic Poisoning; Arsenicals; Cacodylic Acid; Dose-Response Relationship, Drug; Evoked Potentials; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Organometallic Compounds; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials; Synaptic Transmission; Time Factors | 2009 |
Effects of co-administration of dietary sodium arsenite and an NADPH oxidase inhibitor on the rat bladder epithelium.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetophenones; Acetylcysteine; Animals; Antioxidants; Arsenites; Ascorbic Acid; Cacodylic Acid; Carcinogens; Cell Line; Cell Proliferation; Cytoprotection; Deoxyguanosine; Diet; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hyperplasia; NADPH Oxidases; Oxidative Stress; Rats; Rats, Inbred F344; Sodium Compounds; Urinary Bladder; Urothelium | 2009 |
Effects of an epidermal growth factor receptor inhibitor on arsenic associated toxicity in the rat bladder epithelium.
Topics: Animals; Arsenites; Body Weight; Cacodylic Acid; Cell Growth Processes; Cell Line; Cell Survival; Drinking; Eating; ErbB Receptors; Female; Gefitinib; Histocytochemistry; Quinazolines; Random Allocation; Rats; Rats, Inbred F344; Urinary Bladder | 2009 |
[Dimethylarsinous acid-promoted skin tumorigenesis through the induction of oxidative stress in mice].
Topics: 8-Hydroxy-2'-Deoxyguanosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cacodylic Acid; Carcinogens; Deoxyguanosine; Female; Mice; Mice, Hairless; Oxidative Stress; Skin Neoplasms | 2009 |
Trivalent dimethylarsenic compound induces histone H3 phosphorylation and abnormal localization of Aurora B kinase in HepG2 cells.
Topics: Arsenites; Aurora Kinase B; Aurora Kinases; Benzamides; Blotting, Western; Cacodylic Acid; Cell Line; Cell Survival; Centrosome; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Histones; Humans; Liver; Mitotic Index; Phosphorylation; Protein Serine-Threonine Kinases; Quinazolines; Spindle Apparatus | 2009 |
Distribution and metabolism of four different dimethylated arsenicals in hamsters.
Topics: Animals; Cacodylic Acid; Cricetinae; Erythrocytes; Kidney; Liver; Lung; Male; Mesocricetus; Skin | 2010 |
Association of genetic variation in cystathionine-beta-synthase and arsenic metabolism.
Topics: Adult; Aged; Aged, 80 and over; Arsenic; Arsenicals; Cacodylic Acid; Cystathionine beta-Synthase; Environmental Exposure; Female; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Water Pollutants | 2010 |
Superoxide dismutase protects cells from DNA damage induced by trivalent methylated arsenicals.
Topics: Animals; Arsenites; Cacodylic Acid; Carcinogens, Environmental; DNA Damage; Female; Heterozygote; Male; Mice; Mice, Knockout; Organometallic Compounds; Sodium Compounds; Spleen; Superoxide Dismutase | 2011 |
Direct analysis of methylated trivalent arsenicals in mouse liver by hydride generation-cryotrapping-atomic absorption spectrometry.
Topics: Animals; Arsenic; Cacodylic Acid; Liver; Methylation; Mice; Oxidation-Reduction; Spectrophotometry, Atomic; Water Pollutants, Chemical | 2011 |
In vitro study of intestinal transport of arsenite, monomethylarsonous acid, and dimethylarsinous acid by Caco-2 cell line.
Topics: Arsenites; Biological Transport; Caco-2 Cells; Cacodylic Acid; Glutathione; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Organometallic Compounds; Permeability; Plant Extracts; Tea; Temperature | 2011 |
Mitochondria are the main target organelle for trivalent monomethylarsonous acid (MMA(III))-induced cytotoxicity.
Topics: Animals; Apoptosis; Arsenites; Cacodylic Acid; Cell Line; Cell Survival; Electron Transport Complex II; Electron Transport Complex IV; Male; Mitochondria; Organometallic Compounds; Rats; Rats, Wistar; Reactive Oxygen Species; Time Factors | 2011 |
Exposure to arsenic in drinking water is associated with increased prevalence of diabetes: a cross-sectional study in the Zimapán and Lagunera regions in Mexico.
Topics: Adolescent; Adult; Arsenic; Arsenic Poisoning; Arsenicals; Blood Glucose; Cacodylic Acid; Cross-Sectional Studies; Diabetes Mellitus; Environmental Exposure; Female; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; Insulin Resistance; Male; Mexico; Middle Aged; Prevalence; Water Supply | 2011 |
Identification of catalytic residues in the As(III) S-adenosylmethionine methyltransferase.
Topics: Amino Acid Substitution; Arsenic; Cacodylic Acid; Catalytic Domain; Conserved Sequence; Cysteine; DNA Methylation; Methyltransferases; Protein Binding; Rhodophyta; Substrate Specificity | 2012 |
Effects of manganese and arsenic species on the level of energy related nucleotides in human cells.
Topics: Arsenic; Arsenites; Cacodylic Acid; Cell Line, Tumor; Energy Metabolism; Humans; Manganese; Nucleotides; Oxidation-Reduction | 2012 |
Release of apoptotic cytochrome C from mitochondria by dimethylarsinous acid occurs through interaction with voltage-dependent anion channel in vitro.
Topics: Animals; Apoptosis; Cacodylic Acid; Cell Line; Cytochromes c; Ion Channels; Mitochondria, Liver; Rats | 2012 |
Mechanisms underlying the inhibitory effects of arsenic compounds on protein tyrosine phosphatase (PTP).
Topics: Arsenites; Binding Sites; Cacodylic Acid; Hep G2 Cells; Humans; Leukocyte Common Antigens; Organometallic Compounds; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2012 |
Effect of dietary treatment with dimethylarsinous acid (DMA(III)) on the urinary bladder epithelium of arsenic (+3 oxidation state) methyltransferase (As3mt) knockout and C57BL/6 wild type female mice.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cacodylic Acid; Cell Death; Cell Proliferation; Diet; Epithelial Cells; Female; Genotype; Immunohistochemistry; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Scanning; Oxidation-Reduction; Urinary Bladder; Urothelium | 2013 |
Reduction of dimethylarsinic acid to the highly toxic dimethylarsinous acid by rats and rat liver cytosol.
Topics: Animals; Cacodylic Acid; Cytosol; Erythrocytes; Glutathione; Glutathione S-Transferase pi; Glyceraldehyde-3-Phosphate Dehydrogenases; Herbicides; Liver; Male; Methyltransferases; Oxidation-Reduction; Purine-Nucleoside Phosphorylase; Rats; Rats, Wistar; Sulfhydryl Compounds; Thioredoxin-Disulfide Reductase | 2013 |
Characterization of intracellular inclusions in the urothelium of mice exposed to inorganic arsenic.
Topics: Animals; Cacodylic Acid; Carcinogens; Cell Nucleus; Dose-Response Relationship, Drug; Female; Inclusion Bodies; Methyltransferases; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondria; Time Factors; Urinary Bladder; Urothelium | 2014 |
Trivalent arsenic species induce changes in expression and levels of proinflammatory cytokines in intestinal epithelial cells.
Topics: Arsenic; Caco-2 Cells; Cacodylic Acid; Cytokines; Humans; Interleukin-6; Interleukin-8; Intestinal Mucosa; Organometallic Compounds; RNA, Messenger; Tumor Necrosis Factor-alpha | 2014 |
[Distribution of arsenic species and its DNA damage in subchronic arsenite-exposed mice].
Topics: Animals; Arsenic; Arsenites; Cacodylic Acid; DNA Damage; Drinking Water; Environmental Exposure; Male; Mice; Mice, Inbred C57BL; Tissue Distribution; Toxicity Tests, Subchronic; Water Pollutants, Chemical | 2013 |
Radical model of arsenic(III) toxicity: theoretical and EPR spin trapping studies.
Topics: Arsenites; Cacodylic Acid; Electron Spin Resonance Spectroscopy; Humans; Models, Molecular; Organometallic Compounds; Reactive Oxygen Species; Spin Trapping | 2014 |
Speciation of arsenic in saliva samples from a population of West Bengal, India.
Topics: Arsenic; Cacodylic Acid; Chromatography, High Pressure Liquid; Female; Humans; India; Linear Models; Male; Organometallic Compounds; Saliva | 2014 |
Proinflammatory effect of trivalent arsenical species in a co-culture of Caco-2 cells and peripheral blood mononuclear cells.
Topics: Arsenicals; Arsenites; Caco-2 Cells; Cacodylic Acid; Coculture Techniques; Cytokines; Humans; Interleukin-6; Interleukin-8; Intestinal Mucosa; Leukocytes, Mononuclear; Tumor Necrosis Factor-alpha | 2015 |
A novel pathway for arsenic elimination: human multidrug resistance protein 4 (MRP4/ABCC4) mediates cellular export of dimethylarsinic acid (DMAV) and the diglutathione conjugate of monomethylarsonous acid (MMAIII).
Topics: Arsenic; Arsenicals; Biological Transport; Cacodylic Acid; Cell Line; Glutathione; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organometallic Compounds | 2014 |
Trivalent methylated arsenic metabolites induce apoptosis in human myeloid leukemic HL-60 cells through generation of reactive oxygen species.
Topics: Apoptosis; Arsenic; Arsenic Trioxide; Arsenicals; Arsenites; Cacodylic Acid; HL-60 Cells; Humans; Oxides; Reactive Oxygen Species | 2014 |
[The molecular mechanism of interaction of trivalent dimethylarsinous acid (DMA(III)) binding to rat hemoglobin].
Topics: Animals; Arsenic; Binding Sites; Cacodylic Acid; Chromatography, High Pressure Liquid; Cysteine; Hemoglobins; Mass Spectrometry; Peptide Fragments; Rats | 2014 |
Effect of arsenic compounds on the in vitro differentiation of mouse embryonic stem cells into cardiomyocytes.
Topics: Animals; Arsenic; Cacodylic Acid; Cell Differentiation; Cell Line; Mice; Mouse Embryonic Stem Cells; Myocytes, Cardiac; Organometallic Compounds | 2015 |
The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase.
Topics: Arsenic; Arsenites; Cacodylic Acid; Catalysis; Catalytic Domain; Cysteine; Disulfides; Glutathione; Humans; Methionine; Methyltransferases; Mutation; Recombinant Proteins; S-Adenosylhomocysteine; Spectrometry, Fluorescence; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Proposal for novel metabolic pathway of highly toxic dimethylated arsenics accompanied by enzymatic sulfuration, desulfuration and oxidation.
Topics: Activation, Metabolic; Animals; Cacodylic Acid; Cattle; Chromatography, High Pressure Liquid; Liver; Male; Mass Spectrometry; Metabolic Networks and Pathways; Mice, Inbred ICR; Oxidation-Reduction; Rats; Sulfur; Thiosulfate Sulfurtransferase | 2015 |
Arsenic and Its Methylated Metabolites Inhibit the Differentiation of Neural Plate Border Specifier Cells.
Topics: Animals; Arsenites; Basic Helix-Loop-Helix Transcription Factors; Cacodylic Acid; Cell Differentiation; Cell Line; Embryoid Bodies; Mice; Mouse Embryonic Stem Cells; MSX1 Transcription Factor; MyoD Protein; Neural Plate; Neural Stem Cells; Neurogenesis; Organometallic Compounds; Paired Box Transcription Factors; PAX3 Transcription Factor; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sodium Compounds; SOXE Transcription Factors; Transcription Factors | 2015 |
Methylated arsenic metabolites bind to PML protein but do not induce cellular differentiation and PML-RARα protein degradation.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Biotransformation; Cacodylic Acid; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; HEK293 Cells; HeLa Cells; Humans; Leukemia, Promyelocytic, Acute; Methylation; Nuclear Proteins; Oncogene Proteins, Fusion; Organometallic Compounds; Oxides; Promyelocytic Leukemia Protein; Proteasome Endopeptidase Complex; Protein Binding; Protein Interaction Domains and Motifs; Proteolysis; Sumoylation; Time Factors; Transcription Factors; Tumor Suppressor Proteins | 2015 |
Arsenic Metabolites and Methylation Capacity Among Individuals Living in a Rural Area with Endemic Arseniasis in Inner Mongolia, China.
Topics: Adolescent; Adult; Aged; Arsenic; Arsenicals; Cacodylic Acid; Child; China; Environmental Exposure; Female; Humans; Male; Methylation; Middle Aged; Rural Population | 2016 |
Arsenic levels in immigrant children from countries at risk of consuming arsenic polluted water compared to children from Barcelona.
Topics: Arsenates; Arsenic; Cacodylic Acid; Child; Child, Preschool; Emigrants and Immigrants; Environmental Exposure; Environmental Monitoring; Female; Hair; Hazardous Substances; Humans; Male; Nails; Spain; Water; Water Pollutants, Chemical | 2015 |
Comparative cytotoxicity of fourteen trivalent and pentavalent arsenic species determined using real-time cell sensing.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Hazardous Substances; Toxicity Tests | 2016 |
The relationships between arsenic methylation and both skin lesions and hypertension caused by chronic exposure to arsenic in drinking water.
Topics: Arsenic; Arsenicals; Cacodylic Acid; China; Drinking Water; Environmental Exposure; Female; Humans; Hypertension; Male; Methylation; Prevalence; Skin Diseases; Water Pollutants, Chemical | 2017 |
Raman spectra of thiolated arsenicals with biological importance.
Topics: Arsenicals; Cacodylic Acid; Glutathione; Organometallic Compounds; Quantum Theory; Solutions; Spectrum Analysis, Raman; Vibration; Water | 2018 |
Using mathematical modeling to infer the valence state of arsenicals in tissues: A PBPK model for dimethylarsinic acid (DMA
Topics: Animals; Arsenicals; Cacodylic Acid; Environmental Exposure; Humans; Liver; Methylation; Mice; Models, Theoretical; Risk Assessment; Tissue Distribution | 2019 |
Absorption and speciation of arsenic by microalgae under arsenic-copper Co-exposure.
Topics: Arsenic; Arsenicals; Cacodylic Acid; Copper; Microalgae; Organometallic Compounds | 2021 |