Page last updated: 2024-08-17

dimethyl sulfone and dimethyl sulfoxide

dimethyl sulfone has been researched along with dimethyl sulfoxide in 209 studies

Research

Studies (209)

TimeframeStudies, this research(%)All Research%
pre-199027 (12.92)18.7374
1990's15 (7.18)18.2507
2000's50 (23.92)29.6817
2010's86 (41.15)24.3611
2020's31 (14.83)2.80

Authors

AuthorsStudies
Chishti, SB; Cohen, JB; Cohen, SG; Elkind, JL; Reese, H1
Duer, MJ; Levitt, MH1
Blancquaert, AM; Bruyninckx, W; Dargatz, DA; Jones, RL; McKinnon, AO; Thrall, MA; Traub-Dargatz, JL1
Goldstein, P; Magnano, L; Rojo, J1
Bakke, JE; Huwe, JK; Larsen, GL1
Chirra, AR; DeGruccio, A; Girman, DJ; Klandorf, H1
Abou-Issa, H; James, A; McCabe, D; O'Dwyer, P; Sickle-Santanello, B; Woltering, E1
Kato, Y; Kimura, R; Kogure, T; Sato, M1
Clausen, K; Martin, EW; McCabe, DP; O'Dwyer, PJ; Sickle-Santanello, BJ; Woltering, EA1
Morton, JI; Siegel, BV1
Acomb, C; Calvert, RT; Mehta, AC; Peaker, S1
Layman, DL1
Richmond, VL1
McGann, LE; Walterson, ML1
Mio, T; Sumino, K1
Jacob, SW; Layman, DL1
Alam, SS; Layman, DL1
Bergman, A; Brandt, I; Larsson, Y; Wachtmeister, CA1
Aimoto, T; Kawai, M; Kimura, R; Murata, T; Sato, M1
Bertken, R1
Bergman, A; Letcher, RJ; Norstrom, RJ2
da Conceição, M; de Lima, P; Negrão, R; Ramalho-Santos, J1
de Lima, MC; Negrão, R; Ramalho-Santos, J1
Childs, SJ1
Vega, S; Weintraub, O1
Bernardes, C; de Lima, MC; Ramalho-Santos, J; Valdeira, ML1
Davies, D; Newsome, WH1
Brown, MJ; Hoatson, GL; Vold, RL1
Beauchamp, GK; Singer, AG; Yamazaki, K1
Andresen, BD; Grant, PM; Haas, JS; Whipple, RE1
Bonagamba, TJ; deAzevedo, ER; Schmidt-Rohr, K1
Chalk, JB; Doddrell, DM; Galloway, GJ; Rose, SE1
Blümich, B; Jäger, C; Weingarten, K1
Chen, G; Davies, J; Li, X; Wang, GY; Waters, B1
Aguilar, A; Borrell, A; Haraguchi, K; Kaydoo, DS; Mason, CF; Nyman, M; Siebert, U; Troisi, GM1
Castonguay, A; Cloutier, JF; Drouin, R; O'Connor, TR1
Lin, A; Nguy, CH; Ross, BD; Shic, F1
Rogovin, JL1
Barrager, E; Schauss, AG; Schiller, RN; Veltmann, JR1
Gaby, AR1
Robb-Nicholson, C1
Financsek, I; Glávits, R; Horváth, K; Noker, PE; Schauss, AG; Somfai-Relle, S1
Guedes De Pinho, P; Hogg, T; Rodrigues, P; Silva Ferreira, AC1
Barrager, E; Schauss, AG1
Endoh, T; Habe, H; Nojiri, H; Omori, T; Yoshida, T1
HOLMES, WL; WELCH, AD1
HOLMES, WL1
PRUSOFF, WH1
COOPER, JR1
COOPER, JR; JAFFE, JJ1
KHROMOV-BORISOV, NV; TORF, SF1
KAALEN, MC; VOS, O1
CREASEY, WA; HAFF, RC1
Covaci, A; Letcher, RJ; Maervoet, J; Sandau, CD; Schepens, P1
Choi, JK; Choi, YH; Chung, S; Koh, HJ; Lee, KW; Lim, KM; Moh, JH; Shin, SS1
Hirschinger, JJ; Hologne, M1
Chakraborty, S; Roy, K; Sengupta, C1
Endoh, T; Habe, H; Nojiri, H; Omori, T; Yamane, H1
Engelke, UF; Loss, S; Moskau, D; Mudd, SH; Tangerman, A; Wevers, RA; Willemsen, MA1
Mendelsohn, R; Michniak, B; Song, Y; Strekowski, L; Xiao, C; Zheng, T1
Degani, O; Dosoretz, CG; Gepstein, S; Salman, H1
Axelrod, LJ; Buratovich, N; Howard, P; Kim, LS; Waters, RF1
Fleck, CA1
Athanasiadou, M; Athanassiadis, I; Bergman, A; Bignert, A; Fängström, B; Hovander, L; Kocan, A; Linderholm, L; Petrik, J; Trnovec, T1
Engelke, UF; van der Graaf, M; Wevers, RA; Willemsen, MA1
Bergman, A; Eriksson, J; Haglund, J; Norstrom, K; Silvari, V1
Appleton, J; Magnuson, BA; Matulka, RA; Ryan, B1
Ames, GB; Appleton, J; Magnuson, BA1
Dogné, JM; Masereel, B; Pratico, D; Supuran, CT; Thiry, A1
Athanasiadou, M; Bergman, K; Hertz-Picciotto, I; Kocan, A; Linderholm, L; Park, JS; Trnovec, T1
Endoh, T; Habe, H; Kouzuma, A; Nojiri, H; Omori, T; Yamane, H2
ARCHER, S; TULLAR, BF; WETTERAU, W1
Gregory, PJ; Sperry, M; Wilson, AF1
Berardesca, E; Cameli, N; Cavallotti, C; de Paoli Ambrosi, G; Levy, JL; Piérard, GE1
Bashir, N; Brien, S; Lewith, G; Lewith, H; Prescott, P1
Clark, T; Lane, P; Murray, JS; Politzer, P1
Appelboom, T; Dillemans, M; Van Nedervelde, L1
Cheng, L; Rao, J; Shao, L; Shi, R; Xie, Q; Xu, G1
Cayado, P; de la Muela, MS; García, C; León, R; Manley, W; Marañón, G; Muñoz-Escassi, B; Olábarri, B; Vara, E1
Baek, DY; Kim, DH; Kim, JK; Kim, YH; Lim, H; Shin, HK1
Galanko, JA; Littman, A; Satia, JA; Slatore, CG; White, E1
Ansari, NH; Gin, JB; Wong, IG; Zhang, M1
McDermott, AE; Quinn, CM2
Namera, A; Narai, R; Nishida, M; Sakui, N; Takeuchi, A; Yamamoto, S; Yashiki, M1
Cano, MP; Dragsted, LO; Engelsen, SB; Poulsen, M; Roldán-Marín, E; Sánchez-Moreno, C; Viereck, N; Winning, H1
Cho, CH; Larock, RC; Neuenswander, B1
HARTLES, RL; WILLIAMS, RT1
Gwaltney-Brant, S; Khan, SA; McLean, MK1
Brim, TA; Brown, LP; Center, V; Gray, LF; Springs, S; Wynn, SG1
Brumaghim, JL; Ramoutar, RR1
Bannon, M; Caron, JM; Luis, J; Monteagudo, L; Rosshirt, L; Sternstein, GM1
Zhang, JX; Zhang, YH1
GILMAN, H; LINDBLAD, AE1
Ansari, NH; Campbell, GA; Hogan, D; Liu, P; Shoeb, M; Wong, IG; Xiao, T; Zhang, M1
Bergman, J; Hasimbegovic, V; Pettersson, B; Svensson, PH1
Gupta, S; Mittal, PC; Rai, S; Tripathi, R1
Amirshahrokhi, K; Bohlooli, S; Chinifroush, MM1
Bohlooli, S; Jafari, N; Mazani, M; Mohammadi, S1
Agar, G; Beer, Y; Debbi, EM; Debi, R; Elbaz, A; Fichman, G; Halperin, N; Kardosh, R; Ziv, YB1
Broell, J; Kloesch, B; Liszt, M; Steiner, G1
Barmaki, S; Bohlooli, S; Khoshkhahesh, F; Nakhostin-Roohi, B2
Burke, LM; Castell, LM; Jackson, K; Lundy, B; Miller, JC; Senchina, DS; Stear, SJ1
Dereli, Ö; Tapramaz, R; Türkkan, E1
Fusaro, L; Moretti, B; Moretti, L; Notarnicola, A; Pesce, V; Tafuri, S1
Agarwal, M; Gulick, DT; Josephs, J; Reinmiller, A; Zimmerman, B1
Arafa, NM; Darwish, SK; Hamuda, HM; Melek, ST1
Cho, BW; Darvin, P; Do Park, K; Hong, DY; Hwang, TS; Joung, YH; Kim, SY; Lee, HK; Lim, EJ; Moon, ES; Na, YM; Park, JH; Park, T; Yang, YM; Ye, SK1
Andreevski, V; Joksimovic, N; Joksimovic, V; Omini, CF; Spasovski, G; Zuccari, C1
Castro-Puyana, M; García, MÁ; Gómara, B; González, MJ; Marina, ML; Pérez-Fernández, V1
Chen, H; Gao, X; Huang, L; Jiang, H; Li, X; Yuan, G; Zheng, J1
Forcignanò, M; Moretti, B; Notarnicola, A; Pesce, V; Tafuri, S; Vicenti, G1
Ezaki, J; Hashimoto, M; Hosokawa, Y; Ishimi, Y1
Candela, V; Gumina, S; Gurzì, MD; Passaretti, D1
Chung, SC; Darvin, P; Do Park, K; Jang, JW; Joung, YH; Kim, HS; Lee, HK; Lim, EJ; Park, T; Yang, YM1
Boecker, A; Boon, H; Kachan, N; Krahn, M; Tsui, T1
Jia, T; Walsh, PJ; Zheng, B1
El Morsy, EM; Kamel, R1
Amirshahrokhi, K; Bohlooli, S1
Bannon, M; Caron, JM; O'Donovan, L; Rosshirt, L1
Bannon, M; Caron, JM; Deckers, PJ; Monteagudo, L; Sanders, M1
Castro-Puyana, M; Gómara, B; González, MJ; Herrero, L1
Back, W; Barneveld, A; Brommer, H; de Grauw, JC; Higler, MH; L'Ami, JJ; Laverty, S; Nielen, M; van Weeren, PR1
Crudden, CM; Nambo, M1
Cho, BW; Choi, YH; Darvin, P; Joung, YH; Kang, DY; Kim, HS; Kim, SY; Lee, HK; Na, YM; Park, JH; Park, KD; Sp, N; Yang, YM; Yoo, YB1
Ansari, NH; Campbell, GA; Hogan, D; Liu, P; Shoeb, M; Syed, MF; Tang, L; Wang, CZ; Zhang, M1
Fedrigo, M; Fiamoncini, J; Hoeschen, C; Höllriegl, V; Hrabě de Angelis, M; Kistler, M; Klingenspor, M; Rozman, J; Szymczak, W1
Aktan, F; Buyukbingol, Z; Karabay, AZ; Sunguroğlu, A1
He, X; Slupsky, CM1
Li, D; Li, H; Li, Y; Ren, X; Zheng, T1
Gao, J; Gao, X; Huang, H; Li, Y; Pan, X; Yuan, G1
Ahn, H; Cho, YW; Kim, J; Kim, YJ; Lee, GS; Lee, MJ1
Arslan, A; Celik, N; Cetin, N; Dogan, H; Dundar, C; Kockara, N; Kurt, N; Ozturk, C; Sener, E; Suleyman, H; Turkoglu, M; Ucuncu, Y1
Basak, A; Bdour, HM; Goswami, M; Majumdar, S; Mitra, T; O'Reilly, P; Rajkumar, A; Trudeau, VL1
Bergfeldt, T; Hanemann, T; Heinzmann, R; Hofmann, A; Indris, S; Lei, B; Migeot, M; Schulz, M; Thißen, E; Ziebert, C1
Dellabiancia, F; Ingardia, A; Merolla, G; Paladini, P; Porcellini, G1
Chang, SH; Cho, BW; Darvin, P; Hwang, TS; Joung, YH; Kang, DY; Kim, DN; Kim, HS; Kim, SY; Kim, WS; Lee, HK; Park, JH; Park, KD; S P, N; Yang, YM; Yoo, YB1
Allouche, AR; Barnes, L; Chambert, S; Compagnon, I; Oomens, J; Schindler, B; Simon, D1
Ansari, NH; Ayadi, AE; Enkhbaatar, P; Finnerty, CC; Goswamy, J; Herndon, DN; Mifflin, R; Papaconstantinou, J; Sousse, L; Wang, CZ1
Caron, JM1
Byun, HJ; Darvin, P; Joung, YH; Kang, DY; Sp, N; Yang, YM; Yoo, YB1
Fiore, A; Maccagnano, G; Moretti, B; Moretti, L; Notarnicola, A; Pesce, V; Tafuri, S1
Alekseeva, LI; Anikin, SG; Kashevarova, NG; Korotkova, TA; Pyanykh, SE; Sharapova, EP; Taskina, EA1
Byun, HJ; Cho, KH; Darvin, P; Joung, YH; Kang, DY; Kim, DN; Lee, HK; Park, KD; Sp, N; Yang, YM1
Wicht, DK1
Aktan, F; Buyukbingol, Z; Hekmatshoar, Y; Karabay, AZ; Koc, A; Ozkan, T; Sunguroglu, A1
Byun, HJ; Darvin, P; Joung, YH; Kang, DY; Lee, CH; Lee, HK; Sp, N; Yang, YM1
Chung, M; Gaspar, JM; Jung, HJ; Kang, MC; Kim, YB; Lee, SH; Macedo, MP; Mantzoros, C; Park, KS; Park, SY; Seo, JA; Sousa-Lima, I1
Bartoletti, R; Cai, T; Gallelli, L; Malossini, G; Mirone, V; Palmieri, A; Tiscione, D; Verze, P1
Becherini, C; Bonomo, P; Delli Paoli, C; Desideri, I; Francolini, G; Greto, D; Livi, L; Loi, M; Meattini, I; Olmetto, E; Perna, M; Scotti, V; Sulprizio, S; Terziani, F1
Bondaryk, M; Braunsdorf, C; Gliniewicz, A; Kazek, M; Mora-Montes, HM; Ochal, Z; Schaller, M; Staniszewska, M1
Benjamin, RL; Bloomer, RJ; Butawan, M1
Jiao, Y; Kim, IH; Kim, YM; Park, JH1
Byun, HJ; Darvin, P; Joung, YH; Kang, DY; Kim, BJ; Kim, JG; P, NS; Park, JU; Yang, YM1
Amirshahrokhi, K; Khalili, AR1
Biz, MT; de Sousa Rosa, FS; Modolo, F; Stuepp, RT1
Lubis, AMT; Marsetyo, AF; Setyohadi, B; Siagian, C; Wonggokusuma, E1
Benjamin, RL; Bloomer, RJ; Buddington, RK; Wong, T1
Li, Z; Shu, J; Sun, W; Xu, C; Yang, B; Zou, Y1
Tamizhselvi, R; Velusamy, RK1
Boixareu, N; Campanera, JM; Navarro, L; Pors, K; Pouplana, R; Pujol, MD; Rosell, G; Sánchez, S1
Kumar, P; Kumar, V; Pratap, S; Sharma, A1
Brito, GAC; da Silva, JA; de Medeiros, PHQS; Dos Santos, AA; Havt, A; Lima, AÂM; Prata, MMG; Rodrigues, FAP; Santos, ADDC; Santos, TCS; Silveira, ER1
Henrotin, Y; Mobasheri, A1
Bedogni, G; Cheleschi, S; Corallo, C; De Palma, A; Fioravanti, A; Franci, D; Giannotti, S; Giordano, N; Volpi, N1
Domińska, K; Habrowska-Górczyńska, DE; Kowalska, K; Piastowska-Ciesielska, AW; Urbanek, KA1
Abdul Rasheed, MS; Bauer, LL; Dilger, RN; Oelschlager, ML; Smith, BN; Whelan, RA1
Crawford, A; Crawford, P; Lystrup, R; Nielson, F1
Benjamin, R; Genovese, KJ; Nisbet, DJ; Poole, TL2
Inglis, BA; Kaiser, LG; Maschmeyer, T; Redfern, RL; Russell, D1
Adiwidjaja, J; Eagles, SK; Eyles, J; Hunter, DJ; Liu, X; McLachlan, AJ; Wang, X1
Aljohani, H; Chellaiah, MA; Senbanjo, LT1
Clarke, HJ; Griffin, C; Kerry, JP; Kilcawley, KN; O'Callaghan, TF; O'Sullivan, MG; Rai, DK1
Del Campo, A; Farrukh, A; Paez, JI; Valbuena-Mendoza, R; Włodarczyk-Biegun, MK1
Cao, SC; Hu, YD; Liu, JB; Yan, HL; Zhang, HF1
Bauer, LL; Dilger, RN; Oelschlager, ML; Rasheed, MSA; Smith, BN; Whelan, RA1
Deveza, LA; Eyles, J; Fedorova, T; Hunter, D; Liu, X; McLachlan, A; Robbins, S; Virk, S1
Jang, KJ; Jo, ES; Kang, DY; Kim, DH; Rugamba, A; Sp, N; Yang, YM1
Bae, SW; Jang, KJ; Jo, ES; Kang, DY; Kim, IH; Liu, Q; Rugamba, A; Sp, N; Yang, YM1
Choung, PH; Ha, SH1
Domińska, K; Habrowska-Górczyńska, DE; Kowalska, K; Kurczewska, D; Piastowska-Ciesielska, AW; Urbanek, KA1
Davis, AA; Gary, MA; McFarlin, BK; Michalik, S; Tanner, EA1
Abdel-Rafei, MK; Thabet, NM1
Antonetti Lamorgese Passeri, C; Berardi, AC; Cataldi, A; Colosimo, A; Gallorini, M; Gissi, C; Oliva, F; Ricci, A1
Hong, MH; Kang, TY; Kim, KM; Kwon, JS; Ryu, JH; Shin, H1
Bauer, LL; Dilger, RN; Jespersen, JC; Rasheed, MSA; Tiwari, UP1
Deveza, LA; Eyles, J; Fedorova, T; Hunter, DJ; Liu, X; McLachlan, AJ; Robbins, S; Virk, S1
Cömert Kılıç, S1
Bertacco, J; Cheri, S; Dalle Carbonare, L; Deiana, M; Marchetto, G; Minoia, A; Mottes, M; Tiso, N; Valenti, MT1
Lee, CY; Lee, DY; Oh, JH; Shim, SM; Shin, JN1
Basit, A; Haverkamp, H; Larsen, J; Mettu, VS; Miller, L; Pavlenco, C; Prasad, B; Skaufel, S; Thompson, K1
Jang, KJ; Jo, ES; Kang, DY; Lee, JM; Sp, N1
Bao, J; Ishfaq, M; Jin, X; Li, J; Li, R; Miao, Y; Niu, D; Wang, J; Wang, Z; Wu, Z1
Amirshahrokhi, K; Niapour, A1
Jung, M; Lindsay, VNG1
Ao, S; Li, J; Liang, H; Liang, X; Liu, B; Liu, H; Ma, W; Tang, W; Xiao, H; Yang, X; Zhang, H; Zhou, J1
Angelini, L; Becherini, C; Bonomo, P; Ciccone, LP; Desideri, I; Francolini, G; Greto, D; Livi, L; Lucidi, S; Meattini, I; Morelli, I; Salvestrini, V; Scotti, V; Terziani, F; Valzano, M; Visani, L1
Guo, Y; Li, P; Wang, Z; Wu, X; Zhang, P1
Eoh, H; Higuchi, Y; Ishida, Y; Lee, JJ; Li, M; Saito, T; Sugahara, G; Tanaka, Y1
Kanno, T; Noguchi, N; Toguchi, A; Yamada, A1
Aonbangkhen, C; Chaiyen, P; Insin, N; Mangkalee, M; Oonanant, W; Pimviriyakul, P; Sucharitakul, J; Tinikul, R1

Reviews

10 review(s) available for dimethyl sulfone and dimethyl sulfoxide

ArticleYear
Methylsulfonylmethane (MSM). Monograph.
    Alternative medicine review : a journal of clinical therapeutic, 2003, Volume: 8, Issue:4

    Topics: Analgesics; Animals; Autoimmune Diseases; Chemoprevention; Cystitis, Interstitial; Dimethyl Sulfoxide; Humans; Rats; Rhinitis, Allergic, Seasonal; Sulfones

2003
Managing ichthyosis: a case study.
    Ostomy/wound management, 2006, Volume: 52, Issue:4

    Topics: Adult; Amino Acids; Antioxidants; Dimethyl Sulfoxide; Emollients; Humans; Ichthyosis, X-Linked; Male; Nonprescription Drugs; Patient Satisfaction; Silicones; Skin Care; Sulfones; Treatment Outcome; Vitamins

2006
Dual carbonic anhydrase--cyclooxygenase-2 inhibitors.
    Current topics in medicinal chemistry, 2007, Volume: 7, Issue:9

    Topics: Antineoplastic Agents; Carbonic Anhydrase Inhibitors; Cyclooxygenase 2 Inhibitors; Dimethyl Sulfoxide; Humans; Protein Isoforms; Sulfonamides; Sulfones

2007
Dietary supplements for osteoarthritis.
    American family physician, 2008, Jan-15, Volume: 77, Issue:2

    Topics: Anti-Inflammatory Agents; Chondroitin Sulfates; Curcuma; Dietary Supplements; Dimethyl Sulfoxide; Glucosamine; Harpagophytum; Humans; Osteoarthritis; Phytotherapy; Plant Preparations; S-Adenosylmethionine; Sulfones; Treatment Outcome; Zingiber officinale

2008
Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM) in the treatment of osteoarthritis.
    Osteoarthritis and cartilage, 2008, Volume: 16, Issue:11

    Topics: Anti-Inflammatory Agents; Dietary Supplements; Dimethyl Sulfoxide; Free Radical Scavengers; Humans; Osteoarthritis; Randomized Controlled Trials as Topic; Sulfones

2008
Antioxidant and anticancer properties and mechanisms of inorganic selenium, oxo-sulfur, and oxo-selenium compounds.
    Cell biochemistry and biophysics, 2010, Volume: 58, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Cell Death; Dimethyl Sulfoxide; Disulfides; Humans; Methionine; Neoplasms; Organoselenium Compounds; Oxidants; Reactive Oxygen Species; Selenium; Sulfinic Acids; Sulfones; Sulfur

2010
A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance - part 25.
    British journal of sports medicine, 2011, Volume: 45, Issue:13

    Topics: Anti-Inflammatory Agents; Athletic Performance; Dietary Supplements; Dimethyl Sulfoxide; Humans; Jet Lag Syndrome; Melatonin; Sulfones; Triazines

2011
Metabolic fingerprint of dimethyl sulfone (DMSO2) in microbial-mammalian co-metabolism.
    Journal of proteome research, 2014, Dec-05, Volume: 13, Issue:12

    Topics: Animals; Dimethyl Sulfoxide; Host-Pathogen Interactions; Humans; Intestinal Mucosa; Intestines; Mammals; Metabolic Networks and Pathways; Metabolome; Metabolomics; Microbiota; Sulfones

2014
Methylsulfonylmethane: Applications and Safety of a Novel Dietary Supplement.
    Nutrients, 2017, Mar-16, Volume: 9, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis; Biological Availability; Cartilage; Dietary Supplements; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypersensitivity; Inflammation; Myalgia; Neoplasms; Oxidative Stress; Risk Factors; Sulfones

2017
Natural Products for Promoting Joint Health and Managing Osteoarthritis.
    Current rheumatology reports, 2018, 09-19, Volume: 20, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Biological Products; Boswellia; Chondroitin; Curcumin; Dietary Supplements; Dimethyl Sulfoxide; Flavonoids; Glucosamine; Humans; Osteoarthritis; Pain Management; Phytotherapy; Plant Extracts; Salix; Sulfones

2018

Trials

31 trial(s) available for dimethyl sulfone and dimethyl sulfoxide

ArticleYear
Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy.
    Toxicology letters, 2001, Sep-15, Volume: 123, Issue:2-3

    Topics: Administration, Oral; Adult; Aged; Aspartic Acid; Brain; Brain Chemistry; Choline; Creatine; Dimethyl Sulfoxide; Female; Humans; Inositol; Male; Memory Disorders; Middle Aged; Nuclear Magnetic Resonance, Biomolecular; Sulfones; Time Factors

2001
A multicentered, open-label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis.
    Journal of alternative and complementary medicine (New York, N.Y.), 2002, Volume: 8, Issue:2

    Topics: Administration, Oral; Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; C-Reactive Protein; Dimethyl Sulfoxide; Female; Histamine; Humans; Immunoglobulin E; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Sulfones; Time Factors; Treatment Outcome; United States

2002
Dimethyl sulfone in human cerebrospinal fluid and blood plasma confirmed by one-dimensional (1)H and two-dimensional (1)H-(13)C NMR.
    NMR in biomedicine, 2005, Volume: 18, Issue:5

    Topics: Adolescent; Adult; Aged; Biomarkers; Carbon Isotopes; Child; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Infant; Infant, Newborn; Magnetic Resonance Spectroscopy; Male; Metabolic Diseases; Middle Aged; Nervous System Diseases; Protons; Sulfones

2005
Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial.
    Osteoarthritis and cartilage, 2006, Volume: 14, Issue:3

    Topics: Adult; Aged; Analgesics; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain; Pilot Projects; Severity of Illness Index; Sulfones; Treatment Outcome

2006
Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluation.
    Journal of cosmetic dermatology, 2008, Volume: 7, Issue:1

    Topics: Administration, Cutaneous; Adult; Analysis of Variance; Anti-Inflammatory Agents; Antioxidants; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Rosacea; Severity of Illness Index; Silymarin; Skin; Sulfones; Treatment Outcome; Ultraviolet Rays

2008
Effects of AR7 Joint Complex on arthralgia for patients with osteoarthritis: results of a three-month study in Shanghai, China.
    Nutrition journal, 2008, Oct-27, Volume: 7

    Topics: Anti-Inflammatory Agents; Arthralgia; Arthrography; China; Collagen Type II; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Female; Humans; Joints; Male; Middle Aged; Osteoarthritis; Pain; Quality of Life; Sulfones; Surveys and Questionnaires; Treatment Outcome

2008
The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise.
    Acta veterinaria Scandinavica, 2008, Nov-07, Volume: 50

    Topics: Animals; Ascorbic Acid; Dietary Supplements; Dimethyl Sulfoxide; Female; Horses; Male; Oxidative Stress; Physical Conditioning, Animal; Sulfones

2008
Effect of topical application of methylsulfonylmethane (MSM), EDTA on pitting edema and oxidative stress in a double blind, placebo-controlled study.
    Cellular and molecular biology (Noisy-le-Grand, France), 2011, Feb-12, Volume: 57, Issue:1

    Topics: Administration, Topical; Adult; Aged; Anti-Inflammatory Agents; Chelating Agents; Dimethyl Sulfoxide; Double-Blind Method; Edema; Edetic Acid; Humans; Leg; Middle Aged; Oxidative Stress; Sulfones

2011
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study.
    BMC complementary and alternative medicine, 2011, Jun-27, Volume: 11

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Analysis of Variance; Anti-Inflammatory Agents; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Female; Humans; Knee Joint; Locomotion; Male; Middle Aged; Mobility Limitation; Osteoarthritis, Knee; Pain; Pain Measurement; Prospective Studies; Quality of Life; Sulfones

2011
Effect of chronic supplementation with methylsulfonylmethane on oxidative stress following acute exercise in untrained healthy men.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:10

    Topics: Adult; Antioxidants; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Exercise; Glutathione; Glutathione Disulfide; Humans; Male; Malondialdehyde; Oxidative Stress; Protein Carbonylation; Running; Sulfones; Young Adult

2011
The "MESACA" study: methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis.
    Advances in therapy, 2011, Volume: 28, Issue:10

    Topics: Aged; Anti-Inflammatory Agents; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Osteoarthritis, Knee; Pain Measurement; Prospective Studies; Sulfones; Triterpenes

2011
Effects of MagPro™ on muscle performance.
    Journal of strength and conditioning research, 2012, Volume: 26, Issue:9

    Topics: Administration, Cutaneous; Adult; Dimethyl Sulfoxide; Double-Blind Method; Female; Humans; Lower Extremity; Magnesium; Male; Muscle Strength; Muscle, Skeletal; Ointments; Physical Endurance; Sulfones; Young Adult

2012
Efficacy and tolerability of hyaluronic acid, tea tree oil and methyl-sulfonyl-methane in a new gel medical device for treatment of haemorrhoids in a double-blind, placebo-controlled clinical trial.
    Updates in surgery, 2012, Volume: 64, Issue:3

    Topics: Administration, Topical; Adolescent; Anal Canal; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Double-Blind Method; Drug Combinations; Drug Tolerance; Equipment Design; Female; Gels; Hemorrhoids; Humans; Hyaluronic Acid; Male; Pain; Pain Measurement; Sulfones; Tea Tree Oil; Viscosupplements

2012
Effect of methylsulfonylmethane supplementation on exercise - Induced muscle damage and total antioxidant capacity.
    The Journal of sports medicine and physical fitness, 2012, Volume: 52, Issue:2

    Topics: Adult; Antioxidants; Bilirubin; Creatine Kinase; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Exercise; Humans; Male; Muscle, Skeletal; Running; Sulfones; Young Adult

2012
SWAAT study: extracorporeal shock wave therapy and arginine supplementation and other nutraceuticals for insertional Achilles tendinopathy.
    Advances in therapy, 2012, Volume: 29, Issue:9

    Topics: Achilles Tendon; Adult; Aged; Anti-Inflammatory Agents; Arginine; Ascorbic Acid; Bromelains; Collagen; Combined Modality Therapy; Dietary Supplements; Dimethyl Sulfoxide; Female; High-Energy Shock Waves; Humans; Male; Middle Aged; Oximetry; Pain Measurement; Prospective Studies; Sulfones; Tendinopathy; Treatment Outcome; Vitamins

2012
Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study.
    Current medical research and opinion, 2012, Volume: 28, Issue:11

    Topics: Aged; Arginine; Bromelains; Collagen Type I; Dimethyl Sulfoxide; Female; Humans; Hydrolysis; Ketoglutaric Acids; Male; Middle Aged; Prospective Studies; Rotator Cuff Injuries; Shoulder Impingement Syndrome; Sulfones; Wound Healing

2012
The effects of three-month oral supplementation with a nutraceutical and exercise on the locomotor pattern of aged horses.
    Equine veterinary journal, 2014, Volume: 46, Issue:5

    Topics: Administration, Oral; Aging; Animal Feed; Animals; Anti-Inflammatory Agents; Chondroitin Sulfates; Diet; Dietary Supplements; Dimethyl Sulfoxide; Female; Glucosamine; Horses; Locomotion; Male; Physical Conditioning, Animal; Sulfones

2014
Co-analgesic therapy for arthroscopic supraspinatus tendon repair pain using a dietary supplement containing Boswellia serrata and Curcuma longa: a prospective randomized placebo-controlled study.
    Musculoskeletal surgery, 2015, Volume: 99 Suppl 1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arthroscopy; Boswellia; Collagen Type I; Collagen Type II; Curcuma; Dietary Supplements; Dimethyl Sulfoxide; Drug Combinations; Female; Glycosaminoglycans; Humans; Lysine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Phytotherapy; Plant Extracts; Preoperative Care; Prospective Studies; Rotator Cuff Injuries; Rupture; Sulfones

2015
Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial.
    International journal of immunopathology and pharmacology, 2016, Volume: 29, Issue:1

    Topics: Adult; Aged; Dimethyl Sulfoxide; Female; Glucosamine; Humans; Male; Middle Aged; Osteoarthritis, Knee; Prospective Studies; Sulfones; Triterpenes; Visual Analog Scale

2016
[Use of ARTRA MSM FORTE in patients with knee osteoarthritis: Results of a randomized open-label comparative study of the efficacy and tolerability of the drug].
    Terapevticheskii arkhiv, 2015, Volume: 87, Issue:12

    Topics: Aged; Anti-Inflammatory Agents; Chondroitin Sulfates; Dimethyl Sulfoxide; Drug Combinations; Female; Glucosamine; Humans; Hyaluronic Acid; Male; Middle Aged; Osteoarthritis, Knee; Outcome Assessment, Health Care; Sulfones

2015
Serenoa repens associated with selenium and lycopene extract and bromelain and methylsulfonylmethane extract are able to improve the efficacy of levofloxacin in chronic bacterial prostatitis patients.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2016, Oct-05, Volume: 88, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bromelains; Carotenoids; Chronic Disease; Dimethyl Sulfoxide; Drug Therapy, Combination; Follow-Up Studies; Humans; Levofloxacin; Lycopene; Male; Plant Extracts; Prospective Studies; Prostatitis; Selenium; Serenoa; Sulfones; Surveys and Questionnaires; Time Factors; Treatment Outcome

2016
Use of an alpha lipoic, methylsulfonylmethane and bromelain dietary supplement (Opera
    Medical oncology (Northwood, London, England), 2017, Volume: 34, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bromelains; Dietary Supplements; Dimethyl Sulfoxide; Female; Humans; Male; Middle Aged; Neoplasms; Neurotoxins; Peripheral Nervous System Diseases; Prospective Studies; Sulfones; Thioctic Acid

2017
Comparison of Glucosamine-Chondroitin Sulfate with and without Methylsulfonylmethane in Grade I-II Knee Osteoarthritis: A Double Blind Randomized Controlled Trial.
    Acta medica Indonesiana, 2017, Volume: 49, Issue:2

    Topics: Anti-Inflammatory Agents; Chondroitin Sulfates; Dietary Supplements; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Female; Glucosamine; Humans; Male; Middle Aged; Osteoarthritis, Knee; Sulfones; Visual Analog Scale

2017
Methylsulfonylmethane for treatment of low back pain: A safety analysis of a randomized, controlled trial.
    Complementary therapies in medicine, 2019, Volume: 45

    Topics: Adult; Blood; Blood Pressure; Dimethyl Sulfoxide; Double-Blind Method; Female; Humans; Kidney; Liver; Low Back Pain; Male; Middle Aged; Osteoarthritis; Sulfones

2019
Pharmacokinetic assessment of constituents of Boswellia serrata, pine bark extracts, curcumin in combination including methylsulfonylmethane in healthy volunteers.
    The Journal of pharmacy and pharmacology, 2020, Volume: 72, Issue:1

    Topics: Administration, Oral; Adult; Boswellia; Chromatography, High Pressure Liquid; Cross-Over Studies; Curcumin; Dietary Supplements; Dimethyl Sulfoxide; Drug Combinations; Female; Healthy Volunteers; Humans; Male; New South Wales; Pinus; Plant Bark; Plant Extracts; Sulfones; Tandem Mass Spectrometry; Young Adult

2020
Efficacy and safety of a supplement combination for hand osteoarthritis pain: protocol for an internet-based randomised placebo-controlled trial (The RADIANT study).
    BMJ open, 2020, 02-18, Volume: 10, Issue:2

    Topics: Australia; Curcumin; Dimethyl Sulfoxide; Double-Blind Method; Hand; Humans; Internet; Osteoarthritis; Pain Management; Plant Preparations; Quality of Life; Randomized Controlled Trials as Topic; Sulfones; Treatment Outcome

2020
Efficacy and safety of a supplement combination on hand pain among people with symptomatic hand osteoarthritis an internet-based, randomised clinical trial the RADIANT study.
    Osteoarthritis and cartilage, 2021, Volume: 29, Issue:5

    Topics: Aged; Anti-Inflammatory Agents; Boswellia; Curcumin; Dimethyl Sulfoxide; Double-Blind Method; Drug Therapy, Combination; Female; Hand; Humans; Male; Osteoarthritis; Pinus; Plant Bark; Plant Extracts; Sulfones; Visual Analog Scale

2021
Does glucosamine, chondroitin sulfate, and methylsulfonylmethane supplementation improve the outcome of temporomandibular joint osteoarthritis management with arthrocentesis plus intraarticular hyaluronic acid injection. A randomized clinical trial.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 2021, Volume: 49, Issue:8

    Topics: Adolescent; Adult; Arthrocentesis; Chondroitin Sulfates; Dietary Supplements; Dimethyl Sulfoxide; Glucosamine; Humans; Hyaluronic Acid; Injections, Intra-Articular; Osteoarthritis; Range of Motion, Articular; Sulfones; Temporomandibular Joint; Temporomandibular Joint Disorders; Treatment Outcome; Young Adult

2021
The Effect of Daily Methylsulfonylmethane (MSM) Consumption on High-Density Lipoprotein Cholesterol in Healthy Overweight and Obese Adults: A Randomized Controlled Trial.
    Nutrients, 2021, Oct-15, Volume: 13, Issue:10

    Topics: Adult; Biomarkers; C-Reactive Protein; Cholesterol, HDL; Diet; Dimethyl Sulfoxide; Exercise; Female; Fibrosis; Humans; Inflammation; Male; Obesity; Oxidation-Reduction; Sulfones

2021
Use of an alfa-lipoic, Methylsulfonylmethane, Boswellia serrata and Bromelain dietary supplement (OPERA®) for aromatase inhibitors-related arthralgia management (AIA): a prospective phase II trial (NCT04161833).
    Medical oncology (Northwood, London, England), 2022, Jun-06, Volume: 39, Issue:8

    Topics: Aromatase Inhibitors; Arthralgia; Boswellia; Breast Neoplasms; Bromelains; Dietary Supplements; Dimethyl Sulfoxide; Female; Humans; Immunologic Factors; Prospective Studies; Sulfones

2022
Methylsulfonylmethane Improves Knee Quality of Life in Participants with Mild Knee Pain: A Randomized, Double-Blind, Placebo-Controlled Trial.
    Nutrients, 2023, Jun-30, Volume: 15, Issue:13

    Topics: Dimethyl Sulfoxide; Double-Blind Method; Humans; Knee Joint; Osteoarthritis, Knee; Pain; Quality of Life; Treatment Outcome

2023

Other Studies

168 other study(ies) available for dimethyl sulfone and dimethyl sulfoxide

ArticleYear
Effects of charge, volume, and surface on binding of inhibitor and substrate moieties to acetylcholinesterase.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:9

    Topics: Acetylcholinesterase; Binding, Competitive; Butanols; Chemical Phenomena; Chemistry, Physical; Choline; Cholinesterase Inhibitors; Dimethyl Sulfoxide; Ethanol; Kinetics; Structure-Activity Relationship; Sulfones; Sulfonium Compounds; Trimethylsilyl Compounds

1985
Time-domain calculation of chemical exchange effects in the NMR spectra of rotating solids.
    Solid state nuclear magnetic resonance, 1992, Volume: 1, Issue:4

    Topics: Carbon; Carbon Isotopes; Crystallization; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Sulfones

1992
Evaluation of clinical signs of disease, bronchoalveolar and tracheal wash analysis, and arterial blood gas tensions in 13 horses with chronic obstructive pulmonary disease treated with prednisone, methyl sulfonmethane, and clenbuterol hydrochloride.
    American journal of veterinary research, 1992, Volume: 53, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bronchoalveolar Lavage Fluid; Carbon Dioxide; Clenbuterol; Dimethyl Sulfoxide; Evaluation Studies as Topic; Female; Horse Diseases; Horses; Lung Diseases, Obstructive; Male; Oxygen; Phagocytes; Prednisone; Sulfones; Therapeutic Irrigation; Trachea

1992
Effects of dimethyl sulfone (DMSO2) on early gametogenesis in Caenorhabditis elegans: ultrastructural aberrations and loss of synaptonemal complexes from pachytene nuclei.
    Reproductive toxicology (Elmsford, N.Y.), 1992, Volume: 6, Issue:2

    Topics: Animals; Caenorhabditis; Dimethyl Sulfoxide; Female; Gametogenesis; Male; Meiosis; Microscopy, Electron; Mitochondria; Mutagens; Sulfones

1992
Methylsulphone metabolites of m-dichlorobenzene as ligands for alpha 2u-globulin in rat kidney and urine.
    Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:1

    Topics: Alpha-Globulins; Animals; Chlorobenzenes; Chromatography; Dimethyl Sulfoxide; Electrophoresis; Kidney; Male; Organ Specificity; Rabbits; Rats; Rats, Inbred Strains; Sulfones; Xenobiotics

1990
Dimethyl sulfoxide modulation of diabetes onset in NOD mice.
    Diabetes, 1989, Volume: 38, Issue:2

    Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Experimental; Dimethyl Sulfoxide; Female; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred ICR; Mice, Mutant Strains; Reference Values; Sulfides; Sulfones

1989
Polar solvents in the chemoprevention of dimethylbenzanthracene-induced rat mammary cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1986, Volume: 121, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Differentiation; Dimethyl Sulfoxide; Diterpenes; Formamides; Mammary Neoplasms, Experimental; Rats; Rats, Inbred Strains; Retinyl Esters; Solvents; Sulfones; Vitamin A

1986
Contribution of methylsulfonyl metabolites of m-dichlorobenzene to the heme metabolic enzyme induction by the parent compound in rat liver.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Animals; Buthionine Sulfoximine; Chlorobenzenes; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfones; Tryptophan Oxygenase

1988
Use of polar solvents in chemoprevention of 1,2-dimethylhydrazine-induced colon cancer.
    Cancer, 1988, Sep-01, Volume: 62, Issue:5

    Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethyl Sulfoxide; Dimethylhydrazines; Formamides; Gastrointestinal Neoplasms; Male; Methylhydrazines; Rats; Rats, Inbred Strains; Solvents; Sulfones; Time Factors

1988
Effects of oral dimethyl sulfoxide and dimethyl sulfone on murine autoimmune lymphoproliferative disease.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 183, Issue:2

    Topics: Animals; Antibodies, Antinuclear; Autoimmune Diseases; Dimethyl Sulfoxide; Disease Models, Animal; Immunoglobulin G; Immunoglobulin M; Lymphoproliferative Disorders; Male; Mice; Mice, Inbred C3H; Mice, Mutant Strains; Spleen; Sulfones

1986
Rapid gas chromatographic determination of dimethyl sulphoxide and its metabolite dimethyl sulphone in plasma and urine.
    Journal of chromatography, 1986, Dec-19, Volume: 383, Issue:2

    Topics: Chromatography, Gas; Dimethyl Sulfoxide; Humans; Injections, Intravenous; Sulfones

1986
Growth inhibitory effects of dimethyl sulfoxide and dimethyl sulfone on vascular smooth muscle and endothelial cells in vitro.
    In vitro cellular & developmental biology : journal of the Tissue Culture Association, 1987, Volume: 23, Issue:6

    Topics: Animals; Aorta; Cattle; Cell Division; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Endothelium; Muscle, Smooth, Vascular; Sulfones; Time Factors

1987
Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins.
    Life sciences, 1986, Jul-21, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Cysteine; Dimethyl Sulfoxide; Guinea Pigs; Intestinal Absorption; Male; Methionine; Sulfones; Sulfur

1986
Cryoprotection by dimethyl sulfoxide and dimethyl sulfone.
    Cryobiology, 1987, Volume: 24, Issue:1

    Topics: Cell Survival; Dimethyl Sulfoxide; Freezing; Humans; Lymphocytes; Sulfones; Tissue Preservation

1987
Mechanism of biosynthesis of methylsulfones from PCBs and related compounds.
    Environmental health perspectives, 1985, Volume: 59

    Topics: Animals; Biotransformation; Carcinogens; Chemical Phenomena; Chemistry; Cysteine; Dimethyl Sulfoxide; Hydrocarbons, Halogenated; Liver; Methionine; Mice; Polychlorinated Biphenyls; Rats; Sulfones

1985
The absorption, metabolism and excretion of dimethyl sulfoxide by rhesus monkeys.
    Life sciences, 1985, Dec-23, Volume: 37, Issue:25

    Topics: Absorption; Animals; Chromatography, Gas; Dimethyl Sulfoxide; Feces; Half-Life; Kinetics; Macaca mulatta; Sulfones

1985
Dimethyl sulfoxide inhibition of prostacyclin production in cultured aortic endothelial cells.
    Annals of the New York Academy of Sciences, 1983, Volume: 411

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cattle; Cells, Cultured; Dimethyl Sulfoxide; Endothelium; Epoprostenol; Prostaglandins; Sulfones

1983
Cysteine and methionine-precursors of methyl sulphone metabolites of 2,4',5-trichlorobiphenyl in mice.
    Chemico-biological interactions, 1980, Volume: 31, Issue:1

    Topics: Animals; Cysteine; Dimethyl Sulfoxide; Female; Inactivation, Metabolic; Lung; Methionine; Mice; Polychlorinated Biphenyls; Sulfones

1980
Induction of hepatic microsomal drug-metabolizing enzymes by sulfur-containing metabolites of chlorinated benzenes in rats.
    Toxicology and applied pharmacology, 1983, Mar-15, Volume: 67, Issue:3

    Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Male; Microsomes, Liver; Pharmaceutical Preparations; Rats; Rats, Inbred Strains; Sulfones

1983
"Crystalline DMSO": DMSO2.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:5

    Topics: Arthritis, Rheumatoid; Dimethyl Sulfoxide; Drug Evaluation; Humans; Male; Sulfones

1983
Geographical distribution and identification of methyl sulphone PCB and DDE metabolites in pooled polar bear (Ursus maritimus) adipose tissue from western hemisphere arctic and subarctic regions.
    The Science of the total environment, 1995, Jan-15, Volume: 160-161

    Topics: Adipose Tissue; Animals; Arctic Regions; Chromatography, Gas; Dichlorodiphenyl Dichloroethylene; Dimethyl Sulfoxide; Male; Polychlorinated Biphenyls; Sulfones; Ursidae

1995
Role of hydrophobic interactions in the fusion activity of influenza and Sendai viruses towards model membranes.
    Bioscience reports, 1994, Volume: 14, Issue:1

    Topics: Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Liposomes; Membrane Fusion; Naphthalenesulfonates; Orthomyxoviridae; Parainfluenza Virus 1, Human; Polyethylene Glycols; Sulfones

1994
Fusion of Sendai virus with model membranes as affected by dehydrating agents and pH: correlation between viral envelope hydrophobicity and fusion activity.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:6

    Topics: Dimethyl Sulfoxide; Fluorescent Dyes; Hydrogen-Ion Concentration; Membrane Fusion; Membranes, Artificial; Naphthalenesulfonates; Parainfluenza Virus 1, Human; Sulfones; Viral Envelope Proteins; Viral Fusion Proteins

1994
Dimethyl sulfone (DMSO2) in the treatment of interstitial cystitis.
    The Urologic clinics of North America, 1994, Volume: 21, Issue:1

    Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Cystitis; Dimethyl Sulfoxide; Female; Humans; Sulfones

1994
Dynamic 2H nuclear magnetic resonance of rotating solids.
    Solid state nuclear magnetic resonance, 1995, Volume: 4, Issue:6

    Topics: Computer Simulation; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Motion; Rotation; Software; Sulfones

1995
Fusion activity of African swine fever virus towards target membranes: lipid dependence and effect of dehydrating agents.
    Biochemistry and molecular biology international, 1995, Volume: 37, Issue:3

    Topics: African Swine Fever Virus; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Lipids; Liposomes; Membrane Fusion; Membranes, Artificial; Polyethylene Glycols; Solubility; Sulfones; Water

1995
An integrated analytical method for determination of polychlorinated aryl methyl sulfone metabolites and polychlorinated hydrocarbon contaminants in biological matrices.
    Analytical chemistry, 1995, Nov-15, Volume: 67, Issue:22

    Topics: Animals; Chromatography, Gas; Dichlorodiphenyl Dichloroethylene; Dimethyl Sulfoxide; Electrochemistry; Environmental Pollutants; Male; Mass Spectrometry; Polychlorinated Biphenyls; Sulfones

1995
Determination of PCB metabolites in Canadian human milk.
    Chemosphere, 1996, Volume: 33, Issue:3

    Topics: Canada; Chromatography, Gel; Chromatography, Thin Layer; Dimethyl Sulfoxide; Environmental Exposure; Female; Gas Chromatography-Mass Spectrometry; Humans; Milk, Human; Molecular Weight; Pesticide Residues; Polychlorinated Biphenyls; Reference Standards; Sulfones

1996
Selective inversion investigations of slow molecular motion in solid state deuteron NMR spectroscopy.
    Solid state nuclear magnetic resonance, 1996, Volume: 6, Issue:2

    Topics: Anisotropy; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Sulfones; Temperature; Thermodynamics

1996
Volatile signals of the major histocompatibility complex in male mouse urine.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-18, Volume: 94, Issue:6

    Topics: Animals; Benzoates; Benzoic Acid; Butyrates; Chromatography, Gas; Chromatography, Ion Exchange; Cresols; Dimethyl Sulfoxide; Discrimination, Psychological; H-2 Antigens; Major Histocompatibility Complex; Male; Maze Learning; Mice; Mice, Inbred Strains; Odorants; Phenols; Phenylacetates; Sulfones; Ultrafiltration

1997
A possible chemical explanation for the events associated with the death of Gloria Ramirez at Riverside General Hospital.
    Forensic science international, 1997, Jun-23, Volume: 87, Issue:3

    Topics: Blood Chemical Analysis; California; Cause of Death; Dimethyl Sulfoxide; Emergency Service, Hospital; Forensic Medicine; Humans; Mutagens; Oxidation-Reduction; Sulfones; Sulfuric Acid Esters

1997
Pure-exchange solid-state NMR.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2000, Volume: 142, Issue:1

    Topics: Carbon Isotopes; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Sulfones

2000
Detection of dimethyl sulfone in the human brain by in vivo proton magnetic resonance spectroscopy.
    Magnetic resonance imaging, 2000, Volume: 18, Issue:1

    Topics: Brain; Dietary Supplements; Dimethyl Sulfoxide; Humans; Magnetic Resonance Spectroscopy; Male; Middle Aged; Reproducibility of Results; Sulfones

2000
Comparative study of motions in dimethylsulfone by noise excitation and solid echo spectroscopy.
    Solid state nuclear magnetic resonance, 2000, Volume: 16, Issue:3

    Topics: Cold Temperature; Deuterium; Dimethyl Sulfoxide; Echo-Planar Imaging; Fourier Analysis; Magnetic Resonance Spectroscopy; Signal Processing, Computer-Assisted; Sulfones; Thermodynamics

2000
Pain. MSM: does it work?
    Harvard health letter, 2000, Volume: 25, Issue:10

    Topics: Analgesics; Dimethyl Sulfoxide; Humans; Pain; Sulfones

2000
Enhanced production of microbial metabolites in the presence of dimethyl sulfoxide.
    The Journal of antibiotics, 2000, Volume: 53, Issue:10

    Topics: Anti-Bacterial Agents; Bacillus; Chloramphenicol; Culture Media; Dimethyl Sulfoxide; Naphthacenes; Organic Chemicals; Plasmids; Streptomyces; Sulfones; Thiostrepton

2000
Bioaccumulation of polychlorinated biphenyls (PCBs) and dichlorodiphenylethane (DDE) methyl sulfones in tissues of seal and dolphin morbillivirus epizootic victims.
    Journal of toxicology and environmental health. Part A, 2001, Jan-12, Volume: 62, Issue:1

    Topics: Adipose Tissue; Animals; Dichlorodiphenyl Dichloroethylene; Dimethyl Sulfoxide; Disease Outbreaks; Dolphins; Environmental Pollutants; Female; Insecticides; Liver; Lung; Morbillivirus; Morbillivirus Infections; Polychlorinated Biphenyls; Proteins; Seals, Earless; Sulfones; Uteroglobin; Uterus

2001
Alkylating agent and chromatin structure determine sequence context-dependent formation of alkylpurines.
    Journal of molecular biology, 2001, Feb-16, Volume: 306, Issue:2

    Topics: Alkylating Agents; Alkylation; Base Sequence; Cell Line, Transformed; Chromatin; Dimethyl Sulfoxide; DNA; DNA Damage; DNA Footprinting; DNA Methylation; Exons; Fragile X Mental Retardation Protein; Guanine; Humans; Lymphocytes; Molecular Conformation; Molecular Sequence Data; Nerve Tissue Proteins; Piperidines; Potassium Permanganate; Promoter Regions, Genetic; Purines; RNA-Binding Proteins; Sulfones; Sulfuric Acid Esters

2001
Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy.
    Toxicology letters, 2002, Mar-28, Volume: 129, Issue:3

    Topics: Antioxidants; Brain; Brain Chemistry; Dimethyl Sulfoxide; Drug Therapy; Humans; Nuclear Magnetic Resonance, Biomolecular; Sulfones

2002
Methylsulfonylmethane as a treatment for seasonal allergic rhinitis: more data needed on pollen counts and questionnaire.
    Journal of alternative and complementary medicine (New York, N.Y.), 2002, Volume: 8, Issue:3

    Topics: Administration, Topical; Allergens; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Humans; Pollen; Research Design; Rhinitis, Allergic, Seasonal; Sulfones; Surveys and Questionnaires

2002
By the way, doctor. Is MSM as good as it sounds? Can you tell me anything about the dietary supplement MSM? I've heard it's supposed to relieve arthritis pain.
    Harvard women's health watch, 2002, Volume: 9, Issue:12

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Dietary Supplements; Dimethyl Sulfoxide; Humans; Sulfones

2002
Toxicity of methylsulfonylmethane in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:10

    Topics: Administration, Topical; Analgesics; Animals; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Female; Kidney; Male; Organ Size; Rats; Rats, Wistar; Sulfones

2002
Influence of some technological parameters on the formation of dimethyl sulfide, 2-mercaptoethanol, methionol, and dimethyl sulfone in port wines.
    Journal of agricultural and food chemistry, 2003, Jan-29, Volume: 51, Issue:3

    Topics: Aldehydes; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Mercaptoethanol; Odorants; Oxygen; Propanols; Sulfates; Sulfides; Sulfones; Time Factors; Wine

2003
Methylsulfonylmethane as a treatment for seasonal allergic rhinitis: additional data on pollen counts and symptom questionnaire.
    Journal of alternative and complementary medicine (New York, N.Y.), 2003, Volume: 9, Issue:1

    Topics: Administration, Topical; Allergens; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Humans; Pollen; Research Design; Rhinitis, Allergic, Seasonal; Seasons; Sulfones

2003
A CysB-regulated and sigma54-dependent regulator, SfnR, is essential for dimethyl sulfone metabolism of Pseudomonas putida strain DS1.
    Microbiology (Reading, England), 2003, Volume: 149, Issue:Pt 4

    Topics: Bacterial Proteins; Culture Media; Dimethyl Sulfoxide; DNA Transposable Elements; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Genes, Essential; Genes, Regulator; Molecular Sequence Data; Mutagenesis, Insertional; Operon; Pseudomonas putida; RNA Polymerase Sigma 54; Sequence Analysis, DNA; Sigma Factor; Sulfates; Sulfones; Sulfur

2003
Will the dietary supplement MSM help relieve my joint pain?
    Mayo Clinic women's healthsource, 2003, Volume: 7, Issue:5

    Topics: Administration, Topical; Anti-Inflammatory Agents; Arthralgia; Dimethyl Sulfoxide; Humans; Sulfones; Treatment Outcome

2003
Biological studies of analogs of orotic acid: 6-uracilsulfonic acid, 6-uracilsulfonamide, and 6-uracil methyl sulfone.
    Cancer research, 1956, Volume: 16, Issue:3

    Topics: Bacteria; Dimethyl Sulfoxide; Organic Chemicals; Orotic Acid; Sulfones; Uracil

1956
Studies on the mode of action of analogues of orotic acid; 6-uracilsulfonic acid, 6-uracilsulfonamide, and 6-uracil methyl sulfone.
    The Journal of biological chemistry, 1956, Volume: 223, Issue:2

    Topics: Dimethyl Sulfoxide; Organic Chemicals; Orotic Acid; Phosphorylases; Sulfones; Uracil

1956
Studies on the mechanism of action of 6-uracil methyl sulfone in mouse Ehrlich ascites tumor cells in vitro.
    Cancer research, 1958, Volume: 18, Issue:5

    Topics: Animals; Carcinoma, Ehrlich Tumor; Dimethyl Sulfoxide; In Vitro Techniques; Mice; Neoplasms, Experimental; Sulfones; Uracil

1958
Studies on 6-uracil methyl sulfone. I. Non-enzymatic metabolism.
    Cancer research, 1958, Volume: 18, Issue:9

    Topics: Dimethyl Sulfoxide; Liver; Sulfones; Uracil

1958
Studies on 6-uracil methyl sulfone. II. Anti-tumor activity.
    Cancer research, 1958, Volume: 18, Issue:9

    Topics: Antineoplastic Agents; Dimethyl Sulfoxide; Humans; Neoplasms; Sulfones; Uracil

1958
[Bis-trimethylammonium and bis-dimethylsulfone compounds of the diphenylethane series as curariform substances].
    Medical radiology, 1961, Volume: 6

    Topics: Dimethyl Sulfoxide; Muscle Relaxants, Central; Sulfones

1961
Protection of tissue-culture cells against ionizing radiation. II. The activity of hypoxia, dimethyl sulphoxide, dimethyl sulphone, glycerol and cysteamine at room temperature and at -196 degrees C.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1962, Volume: 5

    Topics: Cold Temperature; Cysteamine; Dimethyl Sulfoxide; Glycerol; Hypoxia; Radiation-Protective Agents; Radiation, Ionizing; Sulfones; Temperature; Tissue Culture Techniques

1962
Studies on the biochemistry and pharmacology of 6-uracil methyl sulfone.
    Cancer research, 1963, Volume: 23

    Topics: Dimethyl Sulfoxide; Sulfones; Uracil

1963
A reassessment of the nomenclature of polychlorinated biphenyl (PCB) metabolites.
    Environmental health perspectives, 2004, Volume: 112, Issue:3

    Topics: Biotransformation; Dimethyl Sulfoxide; Environmental Pollutants; Hydroxylation; Polychlorinated Biphenyls; Sulfones; Terminology as Topic

2004
A prodrug approach to COX-2 inhibitors with methylsulfone.
    Bioorganic & medicinal chemistry letters, 2004, Apr-05, Volume: 14, Issue:7

    Topics: Animals; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Male; Prodrugs; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Sulfones

2004
Molecular dynamics as studied by static-powder and magic-angle spinning 2H NMR.
    Solid state nuclear magnetic resonance, 2004, Volume: 26, Issue:1

    Topics: Computer Simulation; Crystallography; Deuterium; Dimethyl Sulfoxide; Magnetic Resonance Spectroscopy; Models, Molecular; Motion; Nitrobenzenes; Powders; Reproducibility of Results; Sensitivity and Specificity; Spin Labels; Sulfones

2004
Exploring QSAR with E-state index: selectivity requirements for COX-2 versus COX-1 binding of terphenyl methyl sulfones and sulfonamides.
    Bioorganic & medicinal chemistry letters, 2004, Sep-20, Volume: 14, Issue:18

    Topics: Binding Sites; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dimethyl Sulfoxide; Electricity; Linear Models; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Protein Binding; Quantitative Structure-Activity Relationship; Sulfonamides; Sulfones; Terphenyl Compounds

2004
The sigma54-dependent transcriptional activator SfnR regulates the expression of the Pseudomonas putida sfnFG operon responsible for dimethyl sulphone utilization.
    Molecular microbiology, 2005, Volume: 55, Issue:3

    Topics: Bacterial Proteins; Base Sequence; Binding Sites; Dimethyl Sulfoxide; DNA Transposable Elements; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Mesylates; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Insertional; Operon; Pseudomonas putida; RNA Polymerase Sigma 54; Sequence Analysis, DNA; Sigma Factor; Sulfones; Trans-Activators; Transcription, Genetic

2005
Investigation of iminosulfuranes as novel transdermal penetration enhancers: enhancement activity and cytotoxicity.
    Pharmaceutical research, 2005, Volume: 22, Issue:11

    Topics: Administration, Cutaneous; Animals; Dimethyl Sulfoxide; Drug Delivery Systems; Epidermis; Hydrocortisone; Male; Mice; Mice, Hairless; Quantitative Structure-Activity Relationship; Skin; Skin Absorption; Sulfones; Sulfur Compounds

2005
Synthesis and characterization of a new cutinase substrate, 4-nitrophenyl (16-methyl sulfone ester) hexadecanoate.
    Journal of biotechnology, 2006, Feb-10, Volume: 121, Issue:3

    Topics: Animals; Carboxylic Ester Hydrolases; Catalysis; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Esters; Kinetics; Liver; Magnetic Resonance Spectroscopy; Molecular Structure; Palmitates; Pseudomonas mendocina; Substrate Specificity; Sulfones; Swine

2006
Supplement may ease pain of knee osteoarthritis.
    Health news (Waltham, Mass.), 2006, Volume: 12, Issue:1

    Topics: Analgesics; Arthralgia; Dimethyl Sulfoxide; Humans; Osteoarthritis, Knee; Sulfones

2006
Levels of PCBs and their metabolites in the serum of residents of a highly contaminated area in eastern Slovakia.
    Environmental science & technology, 2006, Jun-15, Volume: 40, Issue:12

    Topics: Adult; Dimethyl Sulfoxide; Environmental Pollutants; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Polychlorinated Biphenyls; Slovakia; Sulfones

2006
Methylsulfonylmethane (MSM) ingestion causes a significant resonance in proton magnetic resonance spectra of brain and cerebrospinal fluid.
    Neuropediatrics, 2006, Volume: 37, Issue:5

    Topics: Brain; Brain Chemistry; Cerebrospinal Fluid; Child; Child, Preschool; Dietary Supplements; Dimethyl Sulfoxide; Female; Humans; Magnetic Resonance Spectroscopy; Male; Sulfones

2006
Enantioselective formation of methyl sulfone metabolites of 2,2',3,3',4,6'-hexachlorobiphenyl in rat.
    Environmental science & technology, 2006, Dec-15, Volume: 40, Issue:24

    Topics: Animals; Chromatography, Gas; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Male; Polychlorinated Biphenyls; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet; Stereoisomerism; Sulfones; Tissue Distribution

2006
Oral developmental toxicity study of methylsulfonylmethane in rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2007, Volume: 45, Issue:6

    Topics: Animals; Body Weight; Dietary Supplements; Dimethyl Sulfoxide; Eating; Female; Fetal Development; Fetus; Litter Size; Male; Maternal Exposure; No-Observed-Adverse-Effect Level; Organ Size; Organogenesis; Pilot Projects; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Sulfones

2007
Pharmacokinetics and distribution of [35S]methylsulfonylmethane following oral administration to rats.
    Journal of agricultural and food chemistry, 2007, Feb-07, Volume: 55, Issue:3

    Topics: Animals; Dietary Supplements; Dimethyl Sulfoxide; Male; Rats; Rats, Sprague-Dawley; Sulfones; Sulfur Radioisotopes; Tissue Distribution

2007
Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia.
    Chemosphere, 2007, Volume: 69, Issue:3

    Topics: Cohort Studies; Dimethyl Sulfoxide; Female; Fetal Blood; Gas Chromatography-Mass Spectrometry; Humans; Polychlorinated Biphenyls; Pregnancy; Slovakia; Sulfones

2007
The ptsP gene encoding the PTS family protein EI(Ntr) is essential for dimethyl sulfone utilization by Pseudomonas putida.
    FEMS microbiology letters, 2007, Volume: 275, Issue:1

    Topics: Bacterial Proteins; Dimethyl Sulfoxide; DNA Transposable Elements; Genes, Bacterial; Mutagenesis, Insertional; Mutation; Phosphoenolpyruvate Sugar Phosphotransferase System; Pseudomonas putida; Sulfones

2007
The resolution of ethyl 1,1-diphenyl-3-dimethyl-aminobutyl sulfone.
    Journal of the American Chemical Society, 1948, Volume: 70, Issue:11

    Topics: Biphenyl Compounds; Dimethyl Sulfoxide; Humans; Sulfones

1948
Transcription factors CysB and SfnR constitute the hierarchical regulatory system for the sulfate starvation response in Pseudomonas putida.
    Journal of bacteriology, 2008, Volume: 190, Issue:13

    Topics: Amino Acid Motifs; Bacterial Proteins; Base Sequence; Dimethyl Sulfoxide; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Bacterial; Genes, Bacterial; Models, Biological; Molecular Sequence Data; Operon; Promoter Regions, Genetic; Protein Binding; Pseudomonas putida; Reverse Transcriptase Polymerase Chain Reaction; RNA Polymerase Sigma 54; Sulfates; Sulfones; Trans-Activators; Transcription Factors; Transcription Initiation Site

2008
Why are dimethyl sulfoxide and dimethyl sulfone such good solvents?
    Journal of molecular modeling, 2008, Volume: 14, Issue:8

    Topics: Computer Simulation; Dimethyl Sulfoxide; Mathematical Computing; Models, Chemical; Solvents; Sulfones

2008
Yeast as a model system for identification of metabolic targets of a 'glucosamine complex' used as a therapeutic agent of osteoarthritis.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2008, Volume: 62, Issue:9

    Topics: Carbon Dioxide; Cell Proliferation; Culture Media; Dimethyl Sulfoxide; Ethanol; Glucosamine; Heat-Shock Response; Hydrogen Peroxide; Hydrogen-Ion Concentration; Osteoarthritis; Oxidative Stress; Plant Extracts; Ribes; Saccharomyces cerevisiae; Silicon; Sulfones

2008
The anti-inflammatory effects of methylsulfonylmethane on lipopolysaccharide-induced inflammatory responses in murine macrophages.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Cell Line; Cell Survival; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Female; I-kappa B Proteins; Inflammation; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred ICR; Nitric Oxide; Nitrites; Sulfones; Tetradecanoylphorbol Acetate; Transcription Factor RelA

2009
Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins and Lifestyle study.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:5

    Topics: Aged; Chondroitin; Colorectal Neoplasms; Dietary Supplements; Dimethyl Sulfoxide; Female; Fish Oils; Garlic; Glucosamine; Humans; Hypericum; Incidence; Lung Neoplasms; Male; Middle Aged; Proportional Hazards Models; Risk Factors; SEER Program; Sulfones; United States

2009
Assessment of methylsulfonylmethane as a permeability enhancer for regional EDTA chelation therapy.
    Drug delivery, 2009, Volume: 16, Issue:5

    Topics: Animals; Blood-Brain Barrier; Chelating Agents; Chelation Therapy; Cornea; Dimethyl Sulfoxide; Drug Synergism; Edetic Acid; Eye; Male; Radioisotopes; Rats; Rats, Sprague-Dawley; Sulfones

2009
Monitoring conformational dynamics with solid-state R 1rho experiments.
    Journal of biomolecular NMR, 2009, Volume: 45, Issue:1-2

    Topics: Alanine; Anisotropy; Dimethyl Sulfoxide; Models, Chemical; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Sulfones

2009
Determination of dimethyl sulfoxide and dimethyl sulfone in urine by gas chromatography-mass spectrometry after preparation using 2,2-dimethoxypropane.
    Biomedical chromatography : BMC, 2010, Volume: 24, Issue:5

    Topics: Adult; Dimethyl Sulfoxide; Gas Chromatography-Mass Spectrometry; Humans; Limit of Detection; Propanols; Sulfones

2010
An exploratory NMR nutri-metabonomic investigation reveals dimethyl sulfone as a dietary biomarker for onion intake.
    The Analyst, 2009, Volume: 134, Issue:11

    Topics: Animals; Antioxidants; Biomarkers; Diet; Dimethyl Sulfoxide; Eating; Ethanol; Magnetic Resonance Spectroscopy; Male; Metabolomics; Nutritional Physiological Phenomena; Onions; Phenylacetates; Plant Extracts; Principal Component Analysis; Rats; Solubility; Sulfones

2009
Diverse methyl sulfone-containing benzo[b]thiophene library via iodocyclization and palladium-catalyzed coupling.
    Journal of combinatorial chemistry, 2010, Mar-08, Volume: 12, Issue:2

    Topics: Catalysis; Cyclization; Dimethyl Sulfoxide; Iodine; Palladium; Sulfones; Thiophenes

2010
The inactivation of p-aminomethylphenyl methyl sulphone (V335) in vivo.
    The Biochemical journal, 1946, Volume: 40, Issue:5-6

    Topics: Benzylamines; Dimethyl Sulfoxide; Humans; Sulfones

1946
Accidental overdosage of joint supplements in dogs.
    Journal of the American Veterinary Medical Association, 2010, Mar-01, Volume: 236, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Creatine; Dietary Supplements; Dimethyl Sulfoxide; Dog Diseases; Dogs; Drug Overdose; Female; Glucosamine; Joint Diseases; Male; Sulfones

2010
More on accidental overdosage of joint supplements.
    Journal of the American Veterinary Medical Association, 2010, May-15, Volume: 236, Issue:10

    Topics: Animals; Dietary Supplements; Dimethyl Sulfoxide; Dog Diseases; Dogs; Drug Industry; Drug Overdose; Glucosamine; Joint Diseases; Organizations; Sulfones; United States

2010
Methyl sulfone induces loss of metastatic properties and reemergence of normal phenotypes in a metastatic cloudman S-91 (M3) murine melanoma cell line.
    PloS one, 2010, Aug-04, Volume: 5, Issue:8

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cellular Senescence; Dimethyl Sulfoxide; Extracellular Matrix; Melanocytes; Melanoma, Experimental; Mice; Neoplasm Metastasis; Phenotype; Sulfones; Time Factors; Wound Healing

2010
Urine-derived key volatiles may signal genetic relatedness in male rats.
    Chemical senses, 2011, Volume: 36, Issue:2

    Topics: Animals; Dimethyl Sulfoxide; Female; Gas Chromatography-Mass Spectrometry; Ketones; Male; Olfactory Perception; Phenols; Phylogeny; Rats; Rats, Inbred BN; Rats, Inbred Lew; Recognition, Psychology; Sex Attractants; Species Specificity; Sulfones; Volatilization

2011
8-Amino-6-quinolyl methyl sulfone.
    Journal of the American Chemical Society, 1946, Volume: 68

    Topics: Dimethyl Sulfoxide; Sulfones

1946
Topical metal chelation therapy ameliorates oxidation-induced toxicity in diabetic cataract.
    Journal of toxicology and environmental health. Part A, 2011, Volume: 74, Issue:6

    Topics: Administration, Topical; Aldehydes; Animals; Cataract; Cell Proliferation; Chelating Agents; Chelation Therapy; Diabetes Complications; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Edetic Acid; Epithelial Cells; Lens, Crystalline; Male; Metals; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfones

2011
Thionations using a P4S10-pyridine complex in solvents such as acetonitrile and dimethyl sulfone.
    The Journal of organic chemistry, 2011, Mar-18, Volume: 76, Issue:6

    Topics: Acetonitriles; Amides; Dimethyl Sulfoxide; Models, Molecular; Molecular Conformation; Phosphorus; Pyridines; Solvents; Sulfones; Sulfur

2011
The effect of methylsulfonylmethane on the experimental colitis in the rat.
    Toxicology and applied pharmacology, 2011, Jun-15, Volume: 253, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Catalase; Colitis; Dimethyl Sulfoxide; Glutathione; Interleukin-1beta; Male; Malondialdehyde; Peroxidase; Rats; Rats, Wistar; Sulfones; Tumor Necrosis Factor-alpha

2011
Cytotoxicity of methylsulfonylmethane on gastrointestinal (AGS, HepG2, and KEYSE-30) cancer cell lines.
    Journal of gastrointestinal cancer, 2012, Volume: 43, Issue:3

    Topics: Anti-Inflammatory Agents; Apoptosis; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cell Cycle; Cell Proliferation; Dimethyl Sulfoxide; Esophageal Neoplasms; Flow Cytometry; Humans; Liver Neoplasms; Stomach Neoplasms; Sulfones; Tumor Cells, Cultured

2012
Dimethyl sulphoxide and dimethyl sulphone are potent inhibitors of IL-6 and IL-8 expression in the human chondrocyte cell line C-28/I2.
    Life sciences, 2011, Sep-26, Volume: 89, Issue:13-14

    Topics: Anti-Inflammatory Agents; Cell Line; Chondrocytes; Dimethyl Sulfoxide; Enzyme Activation; Gene Expression Regulation; Humans; Interleukin-1beta; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Sulfones; Transcription Factor RelA

2011
Experimental and theoretical Electron Paramagnetic Resonance (EPR) study on the temperature-dependent structural changes of methylsulfanylmethane.
    International journal of molecular sciences, 2011, Volume: 12, Issue:8

    Topics: Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Sulfones; Temperature

2011
The effectiveness of Echinacea extract or composite glucosamine, chondroitin and methyl sulfonyl methane supplements on acute and chronic rheumatoid arthritis rat model.
    Toxicology and industrial health, 2013, Volume: 29, Issue:2

    Topics: Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chondroitin Sulfates; Complex Mixtures; Dietary Supplements; Dimethyl Sulfoxide; Disease Models, Animal; Echinacea; Female; Glucosamine; Lysosomes; Plant Extracts; Rats; Stifle; Sulfones

2013
Methylsulfonylmethane suppresses breast cancer growth by down-regulating STAT3 and STAT5b pathways.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Survival; Chlorocebus aethiops; COS Cells; Dimethyl Sulfoxide; Down-Regulation; Female; Gene Expression; Humans; Inhibitory Concentration 50; Mice; Promoter Regions, Genetic; Protein Binding; Receptor, IGF Type 1; STAT3 Transcription Factor; STAT5 Transcription Factor; Sulfones; Tumor Burden; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays

2012
Simultaneous enantioselective separation of polychlorinated biphenyls and their methyl sulfone metabolites by heart-cut MDGC: determination of enantiomeric fractions in fish oils and cow liver samples.
    Chirality, 2012, Volume: 24, Issue:7

    Topics: Animals; beta-Cyclodextrins; Cattle; Chromatography, Gas; Dimethyl Sulfoxide; Fish Oils; Liver; Polychlorinated Biphenyls; Stereoisomerism; Sulfones; Temperature

2012
Copper-catalyzed aerobic oxidation and cleavage/formation of C-S bond: a novel synthesis of aryl methyl sulfones from aryl halides and DMSO.
    Chemical communications (Cambridge, England), 2012, Aug-04, Volume: 48, Issue:60

    Topics: Catalysis; Chemistry Techniques, Synthetic; Copper; Dimethyl Sulfoxide; Halogens; Hydrocarbons, Aromatic; Oxidation-Reduction; Sulfones

2012
Quantifying conformational dynamics using solid-state R₁ρ experiments.
    Journal of magnetic resonance (San Diego, Calif. : 1997), 2012, Volume: 222

    Topics: Algorithms; Anisotropy; Deuterium; Dimethyl Sulfoxide; Kinetics; Models, Chemical; Molecular Conformation; Sulfones; Temperature

2012
Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model.
    Journal of bone and mineral metabolism, 2013, Volume: 31, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cartilage; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Knee Joint; Male; Mice; Osteoarthritis, Knee; Rats; Sulfones

2013
MSM enhances GH signaling via the Jak2/STAT5b pathway in osteoblast-like cells and osteoblast differentiation through the activation of STAT5b in MSCs.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Analysis of Variance; Animals; Blotting, Western; Cell Differentiation; Cell Line, Tumor; Dimethyl Sulfoxide; DNA Primers; Electrophoretic Mobility Shift Assay; Growth Hormone; Immunoprecipitation; Janus Kinase 2; Luciferases; Mesenchymal Stem Cells; Osteoblasts; Osteogenesis; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Signal Transduction; STAT5 Transcription Factor; Sulfones; Tetrazolium Salts; Thiazoles

2012
Understanding the role of scientific evidence in consumer evaluation of natural health products for osteoarthritis an application of the means end chain approach.
    BMC complementary and alternative medicine, 2012, Oct-30, Volume: 12

    Topics: Adult; Aged; Biological Products; Bromelains; Chondroitin; Comprehension; Consumer Behavior; Decision Making; Dimethyl Sulfoxide; Evidence-Based Medicine; Family; Female; Friends; Glucosamine; Health Personnel; Humans; Male; Middle Aged; Osteoarthritis; Sociology; Sulfones; Treatment Outcome

2012
Palladium-catalyzed direct α-arylation of methyl sulfones with aryl bromides.
    Organic letters, 2013, Apr-05, Volume: 15, Issue:7

    Topics: Catalysis; Dimethyl Sulfoxide; Hydrocarbons, Brominated; Palladium; Sulfones

2013
Hepatoprotective effect of methylsulfonylmethane against carbon tetrachloride-induced acute liver injury in rats.
    Archives of pharmacal research, 2013, Volume: 36, Issue:9

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytokines; Dimethyl Sulfoxide; Female; Lipid Peroxidation; Liver; Malondialdehyde; Oxidative Stress; Protective Agents; Rats; Rats, Sprague-Dawley; Sulfones; Superoxide Dismutase

2013
Effect of methylsulfonylmethane on paraquat-induced acute lung and liver injury in mice.
    Inflammation, 2013, Volume: 36, Issue:5

    Topics: Acute Lung Injury; Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Catalase; Dimethyl Sulfoxide; Glutathione; Liver; Liver Failure, Acute; Lung; Male; Malondialdehyde; Mice; Paraquat; Peroxidase; Pulmonary Edema; Sulfones; Superoxide Dismutase; Transglutaminases; Tumor Necrosis Factor-alpha

2013
Methyl sulfone manifests anticancer activity in a metastatic murine breast cancer cell line and in human breast cancer tissue--part I: murine 4T1 (66cl-4) cell line.
    Chemotherapy, 2013, Volume: 59, Issue:1

    Topics: Actins; Animals; Antineoplastic Agents; Breast Neoplasms; Cadherins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dimethyl Sulfoxide; Epithelial-Mesenchymal Transition; Extracellular Matrix; Female; Humans; Mice; Sulfones; Wound Healing

2013
Methyl sulfone manifests anticancer activity in a metastatic murine breast cancer cell line and in human breast cancer tissue--part 2: human breast cancer tissue.
    Chemotherapy, 2013, Volume: 59, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Movement; Cells, Cultured; Dimethyl Sulfoxide; Female; Humans; Hyaluronan Receptors; Mice; Octamer Transcription Factor-3; Sulfones; Wound Healing

2013
Rapid and simultaneous determination of polychlorinated biphenyls and their main metabolites (hydroxylated and methyl sulfonyl) by gas chromatography coupled to mass spectrometry: comparison of different ionisation modes.
    Analytica chimica acta, 2013, Jul-17, Volume: 787

    Topics: Dimethyl Sulfoxide; Fish Oils; Gas Chromatography-Mass Spectrometry; Hydroxylation; Polychlorinated Biphenyls; Sulfones; Time Factors

2013
Modular synthesis of triarylmethanes through palladium-catalyzed sequential arylation of methyl phenyl sulfone.
    Angewandte Chemie (International ed. in English), 2014, Jan-13, Volume: 53, Issue:3

    Topics: Antineoplastic Agents; Boronic Acids; Carbon; Catalysis; Dimethyl Sulfoxide; Hydrogen; Methane; Palladium; Sulfones

2014
Combination of AG490, a Jak2 inhibitor, and methylsulfonylmethane synergistically suppresses bladder tumor growth via the Jak2/STAT3 pathway.
    International journal of oncology, 2014, Volume: 44, Issue:3

    Topics: Animals; Cell Movement; Cell Survival; Dimethyl Sulfoxide; Gene Expression Regulation, Neoplastic; Humans; Janus Kinase 2; Mice; Receptor, IGF Type 1; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Sulfones; Tyrphostins; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays

2014
Metal chelator combined with permeability enhancer ameliorates oxidative stress-associated neurodegeneration in rat eyes with elevated intraocular pressure.
    Free radical biology & medicine, 2014, Volume: 69

    Topics: Animals; Chelating Agents; Dimethyl Sulfoxide; Edetic Acid; Glaucoma; Humans; Intracranial Hypertension; Neuroprotective Agents; Optic Nerve; Oxidative Stress; Permeability; Rats; Retinal Ganglion Cells; Sulfones

2014
Effects of diet-matrix on volatile organic compounds in breath in diet-induced obese mice.
    Journal of breath research, 2014, Volume: 8, Issue:1

    Topics: Acetates; Animals; Biomarkers; Breath Tests; Computer Systems; Diet; Dimethyl Sulfoxide; Exhalation; Feeding Behavior; Humans; Linear Models; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Mice, Obese; Propionates; Sulfones; Volatile Organic Compounds; Weight Gain

2014
Methylsulfonylmethane modulates apoptosis of LPS/IFN-γ-activated RAW 264.7 macrophage-like cells by targeting p53, Bax, Bcl-2, cytochrome c and PARP proteins.
    Immunopharmacology and immunotoxicology, 2014, Volume: 36, Issue:6

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Line; Cell Survival; Cytochromes c; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Flow Cytometry; Interferon-gamma; Lipopolysaccharides; Macrophages; Membrane Potential, Mitochondrial; Mice; Nitric Oxide; Poly(ADP-ribose) Polymerases; Sulfones; Tumor Suppressor Protein p53

2014
Double-addition reaction of aryl methyl sulfones with N-tert-butylsulfinyl imines: diastereoselective and concise synthesis of 2-sulfonylated 1,3-diamines.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2014, Nov-10, Volume: 20, Issue:46

    Topics: Alkylation; Diamines; Dimethyl Sulfoxide; Imines; Stereoisomerism; Sulfones

2014
Ammonium iodide-induced sulfonylation of alkenes with DMSO and water toward the synthesis of vinyl methyl sulfones.
    Chemical communications (Cambridge, England), 2015, Jan-04, Volume: 51, Issue:1

    Topics: Alkenes; Ammonium Compounds; Catalysis; Dimethyl Sulfoxide; Oxidation-Reduction; Quaternary Ammonium Compounds; Stereoisomerism; Sulfones; Water

2015
Methylsulfonylmethane inhibits NLRP3 inflammasome activation.
    Cytokine, 2015, Volume: 71, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrier Proteins; Cell Line, Tumor; Cells, Cultured; Cytokines; Dimethyl Sulfoxide; Gene Expression; Host-Pathogen Interactions; Humans; Immunoblotting; Inflammasomes; Inflammation Mediators; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Listeria monocytogenes; Macrophages; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Salmonella typhimurium; Sulfones

2015
Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation.
    Life sciences, 2015, Jun-01, Volume: 130

    Topics: Animals; Bromelains; Cartilage; Chondroitin Sulfates; Dimethyl Sulfoxide; Disease Models, Animal; Drug Combinations; Formaldehyde; Gene Expression Regulation; Glucosamine; Harpagophytum; Interleukin-1beta; Knee Joint; Male; Osteoarthritis; Plant Extracts; Rats; Rats, Wistar; Sulfones; Tumor Necrosis Factor-alpha

2015
Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations.
    Bioorganic & medicinal chemistry letters, 2015, Volume: 25, Issue:10

    Topics: Coumarins; Dimethyl Sulfoxide; Drug Design; Enzyme Activation; Enzyme Inhibitors; Hep G2 Cells; Humans; Inhibitory Concentration 50; Molecular Structure; Oligopeptides; Proprotein Convertases; Sulfones

2015
Electrolyte Mixtures Based on Ethylene Carbonate and Dimethyl Sulfone for Li-Ion Batteries with Improved Safety Characteristics.
    ChemSusChem, 2015, Jun-08, Volume: 8, Issue:11

    Topics: Diffusion; Dimethyl Sulfoxide; Dioxolanes; Electric Conductivity; Electric Power Supplies; Electrochemistry; Electrodes; Electrolytes; Feasibility Studies; Hot Temperature; Lithium; Safety; Sulfones; Viscosity

2015
The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.
    BMC cancer, 2015, Jun-19, Volume: 15

    Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Estrogen Receptor alpha; Female; Humans; Janus Kinase 2; Neoplasm Metastasis; Receptors, Somatomedin; Signal Transduction; STAT5 Transcription Factor; Sulfones; Tamoxifen; Xenograft Model Antitumor Assays

2015
Anharmonic simulations of the vibrational spectrum of sulfated compounds: application to the glycosaminoglycan fragment glucosamine 6-sulfate.
    Physical chemistry chemical physics : PCCP, 2015, Oct-21, Volume: 17, Issue:39

    Topics: Computer Simulation; Dimethyl Sulfoxide; Glucosamine; Models, Molecular; Quantum Theory; Spectrophotometry, Infrared; Sulfates; Sulfones; Sulfur Dioxide

2015
Topically applied metal chelator reduces thermal injury progression in a rat model of brass comb burn.
    Burns : journal of the International Society for Burn Injuries, 2015, Volume: 41, Issue:8

    Topics: Acrolein; Administration, Cutaneous; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Dehydrogenase, Mitochondrial; Aldehydes; Animals; Burns; Chelating Agents; Copper; Dimethyl Sulfoxide; Disease Models, Animal; Edetic Acid; Immunohistochemistry; Malondialdehyde; Mitochondrial Proteins; Oxidative Stress; Permeability; Rats; Retinal Dehydrogenase; Skin; Sulfones; Trauma Severity Indices; Zinc

2015
Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Cell Hypoxia; Cell Line, Tumor; Child, Preschool; Dimethyl Sulfoxide; Female; Humans; Iron; Mammary Neoplasms, Animal; Melanoma; Mice; MicroRNAs; Neoplasm Metastasis; Neoplasm Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; RNA, Neoplasm; Sulfones

2015
Methylsulfonylmethane inhibits HER2 expression through STAT5b in breast cancer cells.
    International journal of oncology, 2016, Volume: 48, Issue:2

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Dimethyl Sulfoxide; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Promoter Regions, Genetic; Receptor, ErbB-2; Signal Transduction; STAT5 Transcription Factor; Sulfones

2016
Methylsulfonylmethane enhances BMP‑2‑induced osteoblast differentiation in mesenchymal stem cells.
    Molecular medicine reports, 2016, Volume: 14, Issue:1

    Topics: Animals; Biomarkers; Bone Morphogenetic Protein 2; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Dimethyl Sulfoxide; Gene Expression Regulation; Immunohistochemistry; Male; Mesenchymal Stem Cells; Mice; Osteoblasts; Osteogenesis; RNA, Messenger; Signal Transduction; Sulfones

2016
The reduced flavin-dependent monooxygenase SfnG converts dimethylsulfone to methanesulfinate.
    Archives of biochemistry and biophysics, 2016, 08-15, Volume: 604

    Topics: Bacterial Proteins; Catalysis; Dimethyl Sulfoxide; Escherichia coli; Flavin Mononucleotide; Flavins; Flavoproteins; FMN Reductase; Kinetics; Magnetic Resonance Spectroscopy; Methane; Mixed Function Oxygenases; NAD; Substrate Specificity; Sulfinic Acids; Sulfones; Sulfur

2016
Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells.
    International journal of molecular sciences, 2016, Jul-15, Volume: 17, Issue:7

    Topics: Anti-Inflammatory Agents; Apoptosis; Blotting, Western; Cell Survival; Colonic Neoplasms; Dimethyl Sulfoxide; Flow Cytometry; Humans; Microscopy, Fluorescence; Real-Time Polymerase Chain Reaction; Sulfones; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2016
Methylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 Activities.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Animals; Biomarkers; Bone Resorption; Cell Differentiation; Dimethyl Sulfoxide; Gene Expression; Macrophages; Mice; NF-kappa B; Osteoclasts; RANK Ligand; Signal Transduction; STAT3 Transcription Factor; Sulfones; Tartrate-Resistant Acid Phosphatase

2016
Methylsulfonylmethane (MSM), an organosulfur compound, is effective against obesity-induced metabolic disorders in mice.
    Metabolism: clinical and experimental, 2016, Volume: 65, Issue:10

    Topics: 3T3-L1 Cells; Animals; Anti-Obesity Agents; B-Lymphocytes; Blood Glucose; Cholesterol; Diet, High-Fat; Dimethyl Sulfoxide; Femur; Gene Expression; Insulin Resistance; Lipid Metabolism; Liver; Male; Metabolic Diseases; Mice; Mice, Inbred C57BL; Mice, Obese; Myeloid Cells; Obesity; Sulfones; Triglycerides

2016
Effect of serine protease KEX2 on Candida albicans virulence under halogenated methyl sulfones.
    Future microbiology, 2017, Volume: 12

    Topics: Animals; Antifungal Agents; Biofilms; Candida albicans; Candidiasis; Cell Wall; Dimethyl Sulfoxide; Fungal Proteins; Humans; Microbial Sensitivity Tests; Moths; Serine Proteases; Sulfones; Virulence

2017
Effects of dietary methyl sulfonyl methane (MSM) supplementation on growth performance, nutrient digestibility, meat quality, excreta microbiota, excreta gas emission, and blood profiles in broilers.
    Poultry science, 2017, Jul-01, Volume: 96, Issue:7

    Topics: Ammonia; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Diet; Dietary Supplements; Digestion; Dimethyl Sulfoxide; Feces; Hydrogen Sulfide; Male; Meat; Random Allocation; Sulfones

2017
Methylsulfonylmethane Induces G
    Anticancer research, 2017, Volume: 37, Issue:4

    Topics: Apoptosis; Blotting, Western; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cytochromes c; Dimethyl Sulfoxide; G1 Phase; Gingival Neoplasms; Humans; Membrane Potential, Mitochondrial; Mitochondria; Poly(ADP-ribose) Polymerases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfones; Tumor Cells, Cultured

2017
Methylsulfonylmethane is effective against gastric mucosal injury.
    European journal of pharmacology, 2017, Sep-15, Volume: 811

    Topics: Animals; Cytokines; Dimethyl Sulfoxide; Dinoprostone; Gastric Mucosa; Gene Expression Regulation; Matrix Metalloproteinase 9; Mice; NF-kappa B; Nitric Oxide; RNA, Messenger; Stomach Ulcer; Sulfones

2017
Effect of organic silicon, methylsulfonylmethane, and glucosamine sulfate in mandibular bone defects in rats.
    Microscopy research and technique, 2017, Volume: 80, Issue:11

    Topics: Animals; Bone Regeneration; Dimethyl Sulfoxide; Glucosamine; Male; Mandible; Microscopy, Electron, Scanning; Prostheses and Implants; Rats; Silicon; Sulfones; Wound Healing

2017
Small Intestinal Absorption of Methylsulfonylmethane (MSM) and Accumulation of the Sulfur Moiety in Selected Tissues of Mice.
    Nutrients, 2017, Dec-25, Volume: 10, Issue:1

    Topics: Animals; Dimethyl Sulfoxide; Intestinal Absorption; Intestine, Small; Kinetics; Male; Mice, Inbred C57BL; Phosphoadenosine Phosphosulfate; Protein Processing, Post-Translational; Sulfones; Sulfotransferases; Tissue Distribution

2017
Evaluating the relationship between cell viability and volatile organic compound production following DMSO treatment of cultured human cells.
    Die Pharmazie, 2016, 12-01, Volume: 71, Issue:12

    Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; HEK293 Cells; HeLa Cells; Humans; Paclitaxel; Protective Agents; Sulfones; Volatile Organic Compounds

2016
Protective effect of methylsulfonylmethane in caerulein-induced acute pancreatitis and associated lung injury in mice.
    The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:9

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Ceruletide; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Inflammation Mediators; Male; Mice; Pancreatitis; Random Allocation; Sulfones

2018
Synthesis and biological properties of aryl methyl sulfones.
    Bioorganic & medicinal chemistry, 2018, 08-07, Volume: 26, Issue:14

    Topics: Acetic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Carrageenan; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Edema; Humans; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Sulfones; Thermodynamics

2018
The inhibitory and binding studies of methyl-sulfone hydroxamate based inhibitors against LpxC from drug resistant Moraxella catarrhalis using biophysical, biochemical and in silico approaches.
    International journal of biological macromolecules, 2018, Oct-15, Volume: 118, Issue:Pt B

    Topics: Amidohydrolases; Amino Acid Sequence; Anti-Bacterial Agents; Circular Dichroism; Cloning, Molecular; Dimethyl Sulfoxide; Gene Expression; Hydroxamic Acids; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Moraxella catarrhalis; Protein Binding; Sequence Analysis, DNA; Structure-Activity Relationship; Sulfones; Thermodynamics

2018
Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production.
    Scientific reports, 2018, 08-14, Volume: 8, Issue:1

    Topics: Acute Kidney Injury; Animals; Catechols; Dimethyl Sulfoxide; Dimethylamines; Disease Models, Animal; Fatty Alcohols; Feces; Humans; Injections, Intraperitoneal; Male; Metabolome; Metabolomics; Oxidative Stress; Peritonitis; Rats; Rats, Wistar; Sepsis; Sulfones; Survival Analysis; Treatment Outcome

2018
Methylsulfonylmethane and mobilee prevent negative effect of IL-1β in human chondrocyte cultures via NF-κB signaling pathway.
    International immunopharmacology, 2018, Volume: 65

    Topics: Aged; Cell Survival; Chondrocytes; Dimethyl Sulfoxide; Gene Expression Regulation; Humans; Hyaluronic Acid; Interleukin-1beta; Matrix Metalloproteinases; Middle Aged; NF-kappa B; Osteoarthritis; Signal Transduction; Sulfones

2018
Methylsulfonylmethane (organic sulfur) induces apoptosis and decreases invasiveness of prostate cancer cells.
    Environmental toxicology and pharmacology, 2018, Volume: 64

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Movement; Dimethyl Sulfoxide; Humans; Male; Neoplasm Invasiveness; Prostatic Neoplasms; Sulfones

2018
Toxicity and tissue distribution of methylsulfonylmethane following oral gavage in broilers.
    Poultry science, 2019, Oct-01, Volume: 98, Issue:10

    Topics: Administration, Oral; Animal Feed; Animals; Chickens; Diet; Dietary Supplements; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Male; Sulfones; Tissue Distribution

2019
Methylsulfonylmethane exhibits bacteriostatic inhibition of Escherichia coli, and Salmonella enterica Kinshasa, in vitro.
    Journal of applied microbiology, 2019, Volume: 127, Issue:6

    Topics: Anti-Infective Agents; Dimethyl Sulfoxide; Escherichia coli; Food Microbiology; Food Safety; Humans; Microbial Viability; Salmonella enterica; Sulfones

2019
Methylsulfonylmethane (MSM): A chemical shift reference for
    Magnetic resonance in medicine, 2020, Volume: 83, Issue:4

    Topics: Brain; Dimethyl Sulfoxide; Humans; Magnetic Resonance Spectroscopy; Sulfones

2020
Methylsulfonylmethane increases osteogenesis and regulates the mineralization of the matrix by transglutaminase 2 in SHED cells.
    PloS one, 2019, Volume: 14, Issue:12

    Topics: Biomarkers; Calcification, Physiologic; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Dimethyl Sulfoxide; GTP-Binding Proteins; Humans; Osteogenesis; Osteopontin; Protein Glutamine gamma Glutamyltransferase 2; Sp7 Transcription Factor; Stem Cells; Sulfones; Transglutaminases

2019
Dietary Compounds Influencing the Sensorial, Volatile and Phytochemical Properties of Bovine Milk.
    Molecules (Basel, Switzerland), 2019, Dec-19, Volume: 25, Issue:1

    Topics: Animal Feed; Animals; Apigenin; Cattle; Dimethyl Sulfoxide; Female; Genistein; Isoflavones; Milk; Phytochemicals; Sulfones; Volatile Organic Compounds

2019
Thiol-Methylsulfone-Based Hydrogels for 3D Cell Encapsulation.
    ACS applied materials & interfaces, 2020, Feb-19, Volume: 12, Issue:7

    Topics: Cell Culture Techniques; Cell Encapsulation; Cell Movement; Cell Survival; Dimethyl Sulfoxide; Fibroblasts; Gelatin; Human Umbilical Vein Endothelial Cells; Humans; Hydrogels; Maleimides; Polyethylene Glycols; Rheology; Spheroids, Cellular; Sulfhydryl Compounds; Sulfones

2020
Effects of methylsulfonylmethane on growth performance, immunity, antioxidant capacity, and meat quality in Pekin ducks.
    Poultry science, 2020, Volume: 99, Issue:2

    Topics: Animal Feed; Animals; Antioxidants; Diet; Dietary Supplements; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Ducks; Female; Meat; Random Allocation; Sulfones

2020
Dietary methylsulfonylmethane supplementation and oxidative stress in broiler chickens.
    Poultry science, 2020, Volume: 99, Issue:2

    Topics: Animal Feed; Animals; Chickens; Diet; Dietary Supplements; Dimethyl Sulfoxide; Oxidation-Reduction; Oxidative Stress; Random Allocation; Sulfones; T-Lymphocytes

2020
Effect of Methylsulfonylmethane on Proliferation and Apoptosis of A549 Lung Cancer Cells Through G
    Anticancer research, 2020, Volume: 40, Issue:4

    Topics: A549 Cells; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dimethyl Sulfoxide; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Signal Transduction; Sulfones

2020
Sulfur Compounds Inhibit High Glucose-Induced Inflammation by Regulating NF-κB Signaling in Human Monocytes.
    Molecules (Basel, Switzerland), 2020, May-17, Volume: 25, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Dimethyl Sulfoxide; Gene Expression Regulation; Glucose; Humans; Inflammation; Interleukin-1beta; Interleukin-6; Mannitol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Models, Biological; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Protein Kinase C-alpha; Reactive Oxygen Species; Signal Transduction; Sulfones; THP-1 Cells; Toll-Like Receptor 2; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2020
MSM promotes human periodontal ligament stem cells differentiation to osteoblast and bone regeneration.
    Biochemical and biophysical research communications, 2020, 07-12, Volume: 528, Issue:1

    Topics: Animals; Bone Regeneration; Cell Differentiation; Cell Lineage; Cell Proliferation; Core Binding Factor Alpha 1 Subunit; Dimethyl Sulfoxide; Humans; Mice, Inbred BALB C; Mice, Nude; Osteoblasts; Osteocalcin; Osteogenesis; Osteopontin; Periodontal Ligament; Signal Transduction; Sp7 Transcription Factor; Stem Cells; Sulfones; Young Adult

2020
Methylsulfonylmethane Exhibits Bacteriostatic Inhibition of Vancomycin-Resistant
    Microbial drug resistance (Larchmont, N.Y.), 2021, Volume: 27, Issue:1

    Topics: Anti-Inflammatory Agents; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Enterococcus faecium; Humans; Microbial Sensitivity Tests; Sulfones; Vancomycin-Resistant Enterococci

2021
Methylsulfonylmethane sensitizes endometrial cancer cells to doxorubicin.
    Cell biology and toxicology, 2021, Volume: 37, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Dimethyl Sulfoxide; Doxorubicin; Endometrial Neoplasms; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mitogen-Activated Protein Kinase 3; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Sulfones; Superoxide Dismutase

2021
Optimized Curcumin, Pomegranate Extract, and Methylsulfonylmethane Reduce Acute, Systemic Inflammatory Response to a Half-marathon Race.
    Alternative therapies in health and medicine, 2022, Volume: 28, Issue:6

    Topics: Biomarkers; Curcumin; Dietary Supplements; Dimethyl Sulfoxide; Female; Homosexuality, Male; Humans; Inflammation; Male; Marathon Running; Myeloid Differentiation Factor 88; Osteonectin; Pilot Projects; Plant Extracts; Polyphenols; Pomegranate; RNA; Sexual and Gender Minorities; Sulfones; Systemic Inflammatory Response Syndrome

2022
Modulatory effect of methylsulfonylmethane against BPA/γ-radiation induced neurodegenerative alterations in rats: Influence of TREM-2/DAP-12/Syk pathway.
    Life sciences, 2020, Nov-01, Volume: 260

    Topics: Animals; Anti-Inflammatory Agents; Benzhydryl Compounds; Dimethyl Sulfoxide; Estrogens, Non-Steroidal; Female; Gamma Rays; Gene Expression Regulation; Membrane Glycoproteins; Membrane Proteins; Neurodegenerative Diseases; Phenols; Rats; Rats, Wistar; Receptors, Immunologic; Sulfones; Syk Kinase

2020
Conjugation with Methylsulfonylmethane Improves Hyaluronic Acid Anti-Inflammatory Activity in a Hydrogen Peroxide-Exposed Tenocyte Culture In Vitro Model.
    International journal of molecular sciences, 2020, Oct-26, Volume: 21, Issue:21

    Topics: Anti-Inflammatory Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Dimethyl Sulfoxide; Dinoprostone; Drug Synergism; Humans; Hyaluronic Acid; Hydrogen Peroxide; L-Lactate Dehydrogenase; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Nitric Oxide Synthase Type II; Oxidative Stress; Rotator Cuff Injuries; Sulfones; Tenocytes

2020
Osteogenic Properties of Novel Methylsulfonylmethane-Coated Hydroxyapatite Scaffold.
    International journal of molecular sciences, 2020, Nov-12, Volume: 21, Issue:22

    Topics: 3T3 Cells; Animals; Bone Regeneration; Cell Differentiation; Cell Line; Cell Proliferation; Dimethyl Sulfoxide; Durapatite; Mice; Osteogenesis; Porosity; Sulfones; Tissue Engineering; Tissue Scaffolds

2020
Effects of methylsulfonylmethane and neutralizing anti-IL-10 antibody supplementation during a mild Eimeria challenge infection in broiler chickens.
    Poultry science, 2020, Volume: 99, Issue:12

    Topics: Animals; Chickens; Coccidiosis; Diet; Dietary Supplements; Dimethyl Sulfoxide; Eimeria; Eimeria tenella; Interleukin-10; Male; Poultry Diseases; Sulfones

2020
Methylsulfonylmethane enhances MSC chondrogenic commitment and promotes pre-osteoblasts formation.
    Stem cell research & therapy, 2021, 06-05, Volume: 12, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; Chondrocytes; Chondrogenesis; Dimethyl Sulfoxide; Humans; Osteoblasts; Osteogenesis; Sulfones; Zebrafish

2021
Impact of soy lecithin, zinc oxide, and methylsulfonylmethane, as excipient ingredients, on the bioaccessibility and intestinal transport of branched-chain amino acids from animal and plant protein mixtures.
    Food & function, 2021, Nov-15, Volume: 12, Issue:22

    Topics: Amino Acids, Branched-Chain; Animals; Biological Availability; Caco-2 Cells; Dimethyl Sulfoxide; Excipients; Humans; Lecithins; Plant Proteins; Sulfones; Zinc Oxide

2021
Iron Metabolism as a Potential Mechanism for Inducing TRAIL-Mediated Extrinsic Apoptosis Using Methylsulfonylmethane in Embryonic Cancer Stem Cells.
    Cells, 2021, 10-22, Volume: 10, Issue:11

    Topics: Apoptosis; Biomarkers, Tumor; Cell Cycle Checkpoints; Dimethyl Sulfoxide; DNA Damage; Embryonal Carcinoma Stem Cells; Gene Expression Regulation, Neoplastic; Humans; Iron; MicroRNAs; Models, Biological; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Sulfones; TNF-Related Apoptosis-Inducing Ligand; Tumor Suppressor Protein p53; Wnt Signaling Pathway

2021
Methylsulfonylmethane ameliorates inflammation via NF-κB and ERK/JNK-MAPK signaling pathway in chicken trachea and HD11 cells during Mycoplasma gallisepticum infection.
    Poultry science, 2022, Volume: 101, Issue:4

    Topics: Animals; Chickens; Dimethyl Sulfoxide; Inflammation; JNK Mitogen-Activated Protein Kinases; Mycoplasma gallisepticum; Mycoplasma Infections; NF-kappa B; Poultry Diseases; Signal Transduction; Sulfones; Trachea

2022
Methylsulfonylmethane protects against ethanol-induced brain injury in mice through the inhibition of oxidative stress, proinflammatory mediators and apoptotic cell death.
    International immunopharmacology, 2022, Volume: 106

    Topics: Animals; Antioxidants; Apoptosis; Brain Injuries; Dimethyl Sulfoxide; Ethanol; Humans; Mice; Mice, Inbred C57BL; NF-kappa B; Oxidative Stress; Sulfones

2022
One-Pot Synthesis of Strain-Release Reagents from Methyl Sulfones.
    Journal of the American Chemical Society, 2022, 03-23, Volume: 144, Issue:11

    Topics: Butanes; Dimethyl Sulfoxide; Epichlorohydrin; Indicators and Reagents; Sulfones

2022
Methylsulfonylmethane protects against lethal dose MRSA-induced sepsis through promoting M2 macrophage polarization.
    Molecular immunology, 2022, Volume: 146

    Topics: Animals; Dimethyl Sulfoxide; Disease Models, Animal; Macrophage Activation; Macrophages; Methicillin-Resistant Staphylococcus aureus; Mice; Sepsis; Sulfones

2022
Sustained Delivery of Methylsulfonylmethane from Biodegradable Scaffolds Enhances Efficient Bone Regeneration.
    International journal of nanomedicine, 2022, Volume: 17

    Topics: Alkaline Phosphatase; Animals; Bone Regeneration; Collagen; Delayed-Action Preparations; Dimethyl Sulfoxide; Durapatite; Mice; Osteogenesis; Porosity; Rabbits; Sulfones; Sulfur Compounds; Tissue Engineering; Tissue Scaffolds

2022
Long-term cell fate and functional maintenance of human hepatocyte through stepwise culture configuration.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2023, Volume: 37, Issue:2

    Topics: Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Hepatocytes; Humans; Liver

2023
Reaction mechanism and kinetics of the two-component flavoprotein dimethyl sulfone monooxygenase system: Using hydrogen peroxide for monooxygenation and substrate cleavage.
    The FEBS journal, 2023, Volume: 290, Issue:21

    Topics: Dimethyl Sulfoxide; Flavin Mononucleotide; Flavins; Flavoproteins; Hydrogen Peroxide; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Oxidoreductases

2023