Page last updated: 2024-08-22

dimethindene and histamine

dimethindene has been researched along with histamine in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199012 (41.38)18.7374
1990's14 (48.28)18.2507
2000's0 (0.00)29.6817
2010's1 (3.45)24.3611
2020's2 (6.90)2.80

Authors

AuthorsStudies
Dormann, P; Hamelmann, H; Lorenz, W; Schingale, F; Schmal, A; Thermann, M2
Jacobson, ED; Thompson, WJ1
Chauhan, CK; Shahani, SR1
Costa, E; Moret, E; Sautel, M; Theraulaz, M; Towart, R; Weitsch, AF1
Frey, HH; Hashem, A; Scherkl, R1
Geissler, H; Hennings, G; Lukas, H; Rehn, D; Schuster, O2
Casy, AF; Ganellin, CR; Greengrass, PM; Mercer, AD; Nicholson, AN; Pascoe, PA; Turner, C1
Dick, W; Dietz, W; Doenicke, A; Duda, D; Gstrein, B; Kapp, B; Lorenz, W; Sitter, H; Stinner, B1
Dykes, PJ; Hill, S; Lever, LR; Marks, R1
Borchard, U; Hafner, D1
Zanić-Matanić, D1
Adt, M; Baumert, JH; Reimann, HJ; Schmucker, P1
Humphreys, F; Shuster, S1
Doenicke, A; Duka, T; Hoehe, M; Matussek, N; Stephan, U1
Cohen, S; Nissenkorn, I; Rubinstein, R1
Feifel, G; Hutzel, M; Lorenz, W; Schmal, A; Werle, E1
Guillerm, R1
Black, A; Dick, W; Doenicke, A; Duda, D; Junginger, T; Lorenz, W; Menke, H; Sitter, H; Stinner, B; Weber, D1
Duda, D; Lorenz, W; Menke, H; Sitter, H; Stinner, B1
Doenicke, A; Jedrzejewski, A; Lorenz, W; Mayer, M; Moss, J; Ostwald, P; Rau, J1
Doenicke, A; Hoernecke, R; Lorenz, W; Moss, J; Ostwald, P; Toledano, A1
Dotzer, M; Forster, C; Heyer, G; Weisshaar, E1
Schlicker, E; Werthwein, S; Zentner, J1
DOLENDO, EC; ERSHOFF, BH; FIELD, JB; MIRELES, A1
Kyriakidis, K; Palaiologou, M; Tiligada, E; Tiniakos, D; Zampeli, E1
Benedetti, F; Klinger, R; Sabine Bartholomäus, T; Schwender-Groen, L; Sölle, A; Worm, M1
Alario, C; Capriati, V; García-Álvarez, J; Perna, FM; Quivelli, AF; Rossi, FV; Sannicolò, F; Vitale, P1

Trials

14 trial(s) available for dimethindene and histamine

ArticleYear
Antihistaminic efficacy of Ranitidine with & without Dimethendine maleate on histamine-induced cutaneous reactions.
    The Indian journal of medical research, 1992, Volume: 96

    Topics: Adult; Dimethindene; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Male; Ranitidine; Skin Tests

1992
Effect time-course of the inhibition of histamine induced skin reactions by orally applied dimethindene maleate.
    Agents and actions, 1991, Volume: 33, Issue:1-2

    Topics: Adult; Dimethindene; Histamine; Histamine H1 Antagonists; Humans; Kinetics; Male; Urticaria

1991
Controlled clinical trials and cross-sectional studies with plasma histamine measurements and histamine receptor antagonists: solving the problem of preoperative H1- + H2-prophylaxis by asking new questions?
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia; Atracurium; Cimetidine; Cross-Sectional Studies; Dimethindene; Female; Hemodynamics; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Male; Middle Aged; Polygeline; Premedication; Ranitidine

1991
Efficacy of topical dimetindene in experimentally induced pruritus and weal and flare reactions.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1991, Volume: 4, Issue:2

    Topics: Administration, Topical; Adult; Dimethindene; Double-Blind Method; Female; Histamine; Humans; Injections, Subcutaneous; Male; Pruritus; Urticaria

1991
Effect-kinetic characterization of dimethindene maleate following oral administration (Fenistil, Tropfen).
    Fundamental & clinical pharmacology, 1990, Volume: 4, Issue:6

    Topics: Administration, Oral; Adult; Dimethindene; Double-Blind Method; Half-Life; Histamine; Histamine Antagonists; Humans; Hydrocortisone; Male; Random Allocation

1990
The effect of topical dimethindene maleate on weal reactions.
    British journal of clinical pharmacology, 1987, Volume: 23, Issue:2

    Topics: Adult; Aged; Dimethindene; Dose-Response Relationship, Drug; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Skin Tests

1987
Influence of the histaminergic system on opiate-induced neurosecretion and behaviour.
    Psychoneuroendocrinology, 1987, Volume: 12, Issue:4

    Topics: Adult; Affect; Behavior; Blood Glucose; Cimetidine; Dimethindene; Fentanyl; Growth Hormone; Histamine; Humans; Hydrocortisone; Male; Norepinephrine; Prolactin; Radioimmunoassay

1987
[Investigation of the local antihistamine effect of dermatological preparations].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:9

    Topics: Administration, Topical; Clinical Trials as Topic; Dimethindene; Drug Evaluation; Erythema; Gels; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Injections, Intradermal; Placebos

1974
Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia. Trial Group Mainz/Marburg.
    Lancet (London, England), 1994, Apr-16, Volume: 343, Issue:8903

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Cimetidine; Dimethindene; Double-Blind Method; Female; Hemodynamics; Histamine; Histamine Release; Humans; Intraoperative Complications; Male; Middle Aged; Polygeline

1994
Model building strategies for risk analysis of perioperative histamine-related cardiorespiratory disturbances.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44 Suppl 1

    Topics: Aged; Cardiovascular Diseases; Cimetidine; Dimethindene; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Intraoperative Complications; Logistic Models; Middle Aged; Prospective Studies; Respiratory Tract Diseases; Risk; Risk Factors

1995
Effect of oral antihistamine premedication on mivacurium-induced histamine release and side effects.
    British journal of anaesthesia, 1996, Volume: 77, Issue:3

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Dimethindene; Double-Blind Method; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Isoquinolines; Male; Middle Aged; Mivacurium; Neuromuscular Nondepolarizing Agents; Premedication

1996
Administration of H1 and H2 antagonists for chemoprophylaxis: a double-blind, placebo-controlled study in healthy volunteers.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:2

    Topics: Adult; Blood Pressure; Cimetidine; Dimethindene; Double-Blind Method; Erythema; Female; Headache; Heart Rate; Histamine; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Injections, Intravenous; Male; Tachycardia

1997
Experimentally induced pruritus and cutaneous reactions with topical antihistamine and local analgesics in atopic eczema.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1997, Volume: 10, Issue:4

    Topics: Administration, Topical; Adolescent; Adult; Anesthetics, Combined; Anesthetics, Local; Antipruritics; Dermatitis, Atopic; Dimethindene; Female; Histamine; Histamine H1 Antagonists; Humans; Male; Middle Aged; Pruritus

1997
Targeted Use of Placebo Effects Decreases Experimental Itch in Atopic Dermatitis Patients: A Randomized Controlled Trial.
    Clinical pharmacology and therapeutics, 2021, Volume: 110, Issue:2

    Topics: Adolescent; Adult; Aged; Conditioning, Classical; Dermatitis, Atopic; Dimethindene; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Infusions, Intravenous; Male; Middle Aged; Placebo Effect; Pruritus; Skin; Treatment Outcome; Young Adult

2021

Other Studies

15 other study(ies) available for dimethindene and histamine

ArticleYear
Alterations in the circulatory system of anaesthesized dogs following administration of histamine and histamine H1- and H2-Receptor antagonists in relation to plasma histamine levels.
    Agents and actions, 1975, Volume: 5, Issue:5

    Topics: Anesthesia; Animals; Blood Pressure; Burimamide; Cardiac Output; Central Venous Pressure; Dimethindene; Dogs; Female; Hemodynamics; Histamine; Histamine H1 Antagonists; Male; Pulse; Receptors, Drug; Respiration; Time Factors; Vascular Resistance

1975
Comparison of the effects of secretory stimulants and inhibitors on gastric mucosal adenylyl cyclases of various species.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, Volume: 154, Issue:3

    Topics: Adenylyl Cyclases; Animals; Carbachol; Chlorpheniramine; Dimethindene; Dogs; Enzyme Activation; Epinephrine; Female; Fluorides; Gastric Mucosa; Guinea Pigs; Histamine; Male; Metiamide; Pentagastrin; Prostaglandins E; Rabbits; Rats; Secretin; Species Specificity; Tripelennamine

1977
Influence of H1- and H2-receptor antagonists on the circulatory system and on the endogenous plasma histamine concentrations in dogs.
    Agents and actions, 1977, Volume: 7, Issue:1

    Topics: Animals; Blood Pressure; Burimamide; Dimethindene; Dogs; Female; Histamine; Male; Mesenteric Arteries; Respiration; Thiourea; Vascular Resistance

1977
Investigation of the antihistaminic action of dimethindene maleate (Fenistil) and its optical isomers.
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Animals; Atrial Function; Carbachol; Cell Membrane; Cerebral Cortex; Dimethindene; Dose-Response Relationship, Drug; Guanidines; Guinea Pigs; Heart Atria; Histamine; Histamine H1 Antagonists; Ileum; Imidazoles; Impromidine; Muscle Contraction; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Stereoisomerism

1991
Importance of histamine for seizure susceptibility.
    Agents and actions. Supplements, 1991, Volume: 33

    Topics: Animals; Brain; Brocresine; Dimethindene; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histidine Decarboxylase; Male; Mice; Pentylenetetrazole; Promethazine; Pyrimethamine; Seizures

1991
Sedation and histamine H1-receptor antagonism: studies in man with the enantiomers of chlorpheniramine and dimethindene.
    British journal of pharmacology, 1991, Volume: 104, Issue:1

    Topics: Adult; Affect; Animals; Bronchodilator Agents; Chlorpheniramine; Dimethindene; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; In Vitro Techniques; Male; Molecular Conformation; Psychomotor Performance; Radioligand Assay; Receptors, Histamine H1; Sleep; Sleep Stages; Stereoisomerism; Triprolidine

1991
Electrophysiological characterization of histamine receptor subtypes in mammalian heart preparations.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Action Potentials; Animals; Atrioventricular Node; Cimetidine; Dimaprit; Dimethindene; Guinea Pigs; Heart; Histamine; Histamine H1 Antagonists; Imidazoles; Impromidine; In Vitro Techniques; Male; Myocardial Contraction; Rabbits; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Thiourea

1986
[Methodology of a study of histamine reactions in volunteers].
    Acta medica Iugoslavica, 1987, Volume: 41, Issue:4

    Topics: Adult; Cimetidine; Dimethindene; Histamine; Histamine Release; Humans; Middle Aged; Receptors, Histamine

1987
Cardiovascular reaction and plasma histamine concentration after application of atracurium and pancuronium with and without previous prophylaxis with H1- and H2-receptor antagonists.
    Journal of cardiothoracic anesthesia, 1989, Volume: 3, Issue:5 Suppl 1

    Topics: Atracurium; Blood Pressure; Cardiac Output; Cimetidine; Dimethindene; Heart; Heart Rate; Histamine; Histamine Release; Humans; Pancuronium; Premedication; Vascular Resistance

1989
Acetylcholine mediation of the contractile response to histamine in human bladder detrusor muscle.
    European journal of pharmacology, 1987, Oct-06, Volume: 142, Issue:1

    Topics: Acetylcholine; Atropine; Dimethindene; Diphenhydramine; Histamine; Humans; In Vitro Techniques; Muscle, Smooth; Neostigmine; Ranitidine; Urinary Bladder

1987
[Mechanism of secretion stimulation and blood pressure decrease by histalog (betazol): histamine liberation and potentiation of the effect of kinins and serotonin].
    Klinische Wochenschrift, 1970, Mar-01, Volume: 48, Issue:5

    Topics: Acetylcholine; Adenosine Triphosphate; Adult; Angiotensin II; Animals; Blood Pressure; Bradykinin; Cats; Dimethindene; Dogs; Female; Gastric Juice; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypotension; Ileum; In Vitro Techniques; Kallidin; Malates; Male; Norepinephrine; Pyrazoles; Rats; Serotonin

1970
Histamine H3 receptor-mediated inhibition of noradrenaline release in the human brain.
    Fundamental & clinical pharmacology, 1999, Volume: 13, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Dimethindene; Electric Stimulation; Hippocampus; Histamine; Histamine Agonists; Histamine Antagonists; Humans; Imidazoles; Male; Mice; Mice, Inbred Strains; Norepinephrine; Piperidines; Ranitidine; Receptors, Histamine H3; Thiourea; Tritium

1999
REVERSAL OF NITROGEN MUSTARD INTOXICATION BY ANTI-HISTAMINES.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 115

    Topics: Anti-Allergic Agents; Body Weight; Body Weights and Measures; Dimethindene; Histamine; Histamine H1 Antagonists; Leukocyte Count; Mechlorethamine; Mice; Pharmacology; Research; Toxicology

1964
Histamine H3 and H4 receptor ligands modify vascular histamine levels in normal and arthritic large blood vessels in vivo.
    Inflammation, 2015, Volume: 38, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aorta; Arthritis, Experimental; Azepines; Dimethindene; Endothelium; Freund's Adjuvant; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Indoles; Inflammation; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H3; Receptors, Histamine H4; Vena Cava, Inferior

2015
Green Solvents for Eco-Friendly Synthesis of Dimethindene: A Forward-Looking Approach.
    Molecules (Basel, Switzerland), 2022, Nov-05, Volume: 27, Issue:21

    Topics: Dimethindene; Histamine; Methyl Ethers; Solvents

2022