dimethadione has been researched along with phenytoin in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Göbel, W; Löscher, W | 1 |
| Andersen, B; Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Boisse, NR; Okamoto, M; Rosenberg, HC | 1 |
| Anderson, RC | 1 |
| Collins, MD; Resnick, E; Scott, WJ; Walling, KM | 1 |
| Collins, MD; Fradkin, R; Scott, WJ | 1 |
| Greco, GS; Nagai, MK; Wells, PG | 1 |
| Azarbayjani, F; Danielsson, BR | 1 |
| Danielsson, BR; Danielsson, C; Nilsson, MF | 1 |
| Azarbayjani, F; Danielsson, BR; Danielsson, C; Sjögren, N; Sköld, AC | 1 |
1 review(s) available for dimethadione and phenytoin
| Article | Year |
|---|---|
Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs.
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Astemizole; Cisapride; Dimethadione; Ether-A-Go-Go Potassium Channels; Female; Free Radical Scavengers; Gastrointestinal Agents; Heart; Histamine Antagonists; Humans; Hypoxia; Phenytoin; Potassium Channel Blockers; Pregnancy; Reactive Oxygen Species; Teratology; Toxicity Tests | 2007 |
1 trial(s) available for dimethadione and phenytoin
| Article | Year |
|---|---|
Sodium valproate, serum level and clinical effect in epilepsy: a controlled study.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dimethadione; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
9 other study(ies) available for dimethadione and phenytoin
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Evaluation of anticonvulsants in barbiturate withdrawal.
Topics: Animals; Anticonvulsants; Behavior, Animal; Cats; Dimethadione; Female; Humans; Male; Pentobarbital; Phenobarbital; Phenytoin; Seizures; Substance Withdrawal Syndrome; Time Factors; Trimethadione | 1977 |
Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Cleft Lip; Cleft Palate; Dimethadione; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Male; Mephobarbital; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione | 1976 |
The effect of administration time on malformations induced by three anticonvulsant agents in C57BL/6J mice with emphasis on forelimb ectrodactyly.
Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Anticonvulsants; Dimethadione; Facial Bones; Female; Forelimb; Gestational Age; Kidney; Maternal Mortality; Maternal-Fetal Exchange; Mice; Mice, Inbred C57BL; Microphthalmos; Phenytoin; Pregnancy; Skull; Spine; Valproic Acid | 1991 |
Induction of postaxial forelimb ectrodactyly with anticonvulsant agents in A/J mice.
Topics: Abnormalities, Drug-Induced; Animals; Birth Weight; Dimethadione; Female; Fetal Death; Fetal Resorption; Forelimb; Maternal Mortality; Mice; Mice, Inbred A; Oxazoles; Phenytoin; Pregnancy; Valproic Acid | 1990 |
Inhibition of trimethadione and dimethadione teratogenicity by the cyclooxygenase inhibitor acetylsalicylic acid: a unifying hypothesis for the teratologic effects of hydantoin anticonvulsants and structurally related compounds.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cleft Palate; Dealkylation; Dimethadione; Dose-Response Relationship, Drug; Female; Mice; Oxazoles; Phenytoin; Pregnancy; Trimethadione | 1989 |
Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Anticonvulsants; Arrhythmias, Cardiac; Cation Transport Proteins; Dimethadione; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Female; Fetal Diseases; Fetal Heart; Fetal Hypoxia; Gestational Age; Heart Rate, Fetal; Maternal-Fetal Exchange; Mice; Myocardial Ischemia; Myocardial Reperfusion Injury; Patch-Clamp Techniques; Phenytoin; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pregnancy; Reactive Oxygen Species; Trans-Activators; Trimethadione | 2002 |
Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity.
Topics: Animals; Anticonvulsants; Bradycardia; Dimethadione; Dose-Response Relationship, Drug; Drug Therapy, Combination; Embryo Culture Techniques; Embryo, Mammalian; Ether-A-Go-Go Potassium Channels; Female; Gestational Age; Heart; Mice; Mice, Inbred C57BL; Phenytoin; Potassium Channel Blockers; Pregnancy | 2007 |