dimercaprol and acetylcysteine

dimercaprol has been researched along with acetylcysteine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19906 (46.15)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's4 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Baskovich, GA; Kolmakov, VN; Rodionova, LP; Shleĭkin, AG; Zubzhitskiĭ, IuN1
Habersang, RW; Hale, TW; Henderson, P; Shum, S1
Jollow, DJ; Keiser, H; Mitchell, JR; Potter, WZ; Thorgeirsson, SS1
Norseth, T1
Habersang, R; Shum, S; Skarbovig, J1
Ferrari, G; Greene, LA; Yan, CY1
Brash, DE; Chu, E; Ju, J; Liu, M; Pelling, JC1
Bhadauria, S; Flora, SJ; Kannan, GM; Singh, N1
Brok, J; Buckley, NA; Chiew, AL; Gluud, C1

Reviews

3 review(s) available for dimercaprol and acetylcysteine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review.
    Journal of environmental biology, 2007, Volume: 28, Issue:2 Suppl

    Topics: Acetylcysteine; Animals; Antioxidants; Arsenic Poisoning; Ascorbic Acid; Chelating Agents; Chelation Therapy; Dimercaprol; Drug Therapy, Combination; Environmental Pollutants; Humans; Melatonin; Oxidative Stress; Plant Extracts; Selenium; Succimer; Taurine; Thioctic Acid; Vitamin E; Zinc

2007
Interventions for paracetamol (acetaminophen) overdose.
    The Cochrane database of systematic reviews, 2018, 02-23, Volume: 2

    Topics: Acetaminophen; Acetylcysteine; Analgesics, Non-Narcotic; Antidotes; Charcoal; Cysteamine; Dimercaprol; Drug Overdose; Gastric Lavage; Humans; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Methionine; Randomized Controlled Trials as Topic

2018

Trials

1 trial(s) available for dimercaprol and acetylcysteine

ArticleYear
Letter: Cysteamine for paracetamol overdosage.
    Lancet (London, England), 1974, May-18, Volume: 1, Issue:7864

    Topics: Acetaminophen; Acetylcysteine; Blood Specimen Collection; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Penicillamine; Poisoning; Time Factors

1974

Other Studies

9 other study(ies) available for dimercaprol and acetylcysteine

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
[Effect of unithiol and acetylcysteine on lipid peroxidation and the erythrocyte antioxidant system in sensitized guinea pigs].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:5

    Topics: Acetylcysteine; Animals; Candida; Dimercaprol; Erythrocytes; Female; Guinea Pigs; Immunization; Lipid Peroxides; Male; Oxidation-Reduction; Time Factors; Unithiol

1987
N-Acetylcysteine therapy of acute heavy metal poisoning in mice.
    Veterinary and human toxicology, 1985, Volume: 27, Issue:6

    Topics: Acetylcysteine; Acute Disease; Animals; Dimercaprol; Metals; Mice; Penicillamine

1985
Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:4

    Topics: Acetaminophen; Acetylcysteine; Adult; Amobarbital; Animals; Chemical and Drug Induced Liver Injury; Chromatography, Paper; Cysteamine; Cytochrome P-450 Enzyme System; Desipramine; Dimercaprol; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione; Humans; Indicators and Reagents; Liver; Male; Mass Spectrometry; Methyltransferases; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Sulfhydryl Compounds; Time Factors; Tritium

1974
The effect of chelating agents on biliary excretion of methyl mercuric salts in the rat.
    Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:1

    Topics: Acetamides; Acetylcysteine; Animals; Bile; Bile Ducts; Chelating Agents; Dimercaprol; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Mercury; Methylmercury Compounds; Organometallic Compounds; Penicillamine; Rats; Sex Factors; Stimulation, Chemical; Time Factors

1973
Acute lethal arsenite poisoning in mice: effect of treatment with N-acetylcysteine, D-penicillamine and dimercaprol on survival time.
    Veterinary and human toxicology, 1981, Volume: 23, Issue:Suppl 1

    Topics: Acetylcysteine; Animals; Arsenic Poisoning; Dimercaprol; Dose-Response Relationship, Drug; Mice; Penicillamine; Time Factors

1981
N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent.
    The Journal of biological chemistry, 1995, Nov-10, Volume: 270, Issue:45

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Survival; Dimercaprol; DNA; Gene Expression; Glutathione; Mitosis; Oxidation-Reduction; PC12 Cells; Rats; Transcription, Genetic

1995
Antioxidant action via p53-mediated apoptosis.
    Cancer research, 1998, Apr-15, Volume: 58, Issue:8

    Topics: Acetylcysteine; Animals; Antioxidants; Apoptosis; Blotting, Northern; Blotting, Western; Buthionine Sulfoximine; Cells, Cultured; Dimercaprol; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glutathione; Mice; Oxidation-Reduction; Pyrrolidonecarboxylic Acid; Sulfhydryl Compounds; Thiazoles; Thiazolidines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vitamin E

1998