Compounds > diltiazem
Page last updated: 2024-08-23

diltiazem and wortmannin

diltiazem has been researched along with wortmannin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Gilani, AH; Rashid, F; Saeed, SA; Shah, BH1
Cheema, M; Connor, JD; Gilani, AH; Rasheed, H; Rizvi, Z; Saeed, SA1
Bechtel, LK; Haverstick, DM; Holstege, CP1

Other Studies

5 other study(ies) available for diltiazem and wortmannin

ArticleYear
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Dopamine potentiation of calcium ionophore, A-23187-induced platelet aggregation.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Androstadienes; Aspirin; Benzophenanthridines; Calcimycin; Calcium; Chlorpromazine; Diltiazem; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; GTP-Binding Proteins; Haloperidol; Homovanillic Acid; Humans; Indomethacin; Ion Transport; Ionophores; Phenanthridines; Phentolamine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Propranolol; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Dopamine; Serotonin; Signal Transduction; Verapamil; Wortmannin

1997
Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore.
    Life sciences, 2001, Oct-26, Volume: 69, Issue:23

    Topics: Adult; Alkaloids; Androstadienes; Benzophenanthridines; Blood Platelets; Calcimycin; Calcium Channel Blockers; Cyproheptadine; Diltiazem; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Estrenes; Female; Genistein; Humans; In Vitro Techniques; Ionophores; Male; Methysergide; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet Aggregation; Pyrrolidinones; Second Messenger Systems; Serotonin; Type C Phospholipases; Verapamil; Wortmannin

2001
Verapamil toxicity dysregulates the phosphatidylinositol 3-kinase pathway.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2008, Volume: 15, Issue:4

    Topics: Adipocytes; Androstadienes; Animals; Blotting, Western; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Glucose; Insulin; Mice; Nifedipine; Phosphatidylinositol 3-Kinases; Signal Transduction; Verapamil; Wortmannin

2008