Page last updated: 2024-08-23

diltiazem and warfarin

diltiazem has been researched along with warfarin in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (2.56)	18.7374
1990's	11 (28.21)	18.2507
2000's	15 (38.46)	29.6817
2010's	8 (20.51)	24.3611
2020's	4 (10.26)	2.80

Authors

Authors	Studies
Gubernator, K; Kansy, M; Senner, F	1
Topliss, JG; Yoshida, F	1
Caron, G; Ermondi, G	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K	1
Kaufmann, E; Levy, PS; Rich, S	1
Amstey, MS; Menegakis, NE	1
Abernethy, DR; Dickinson, TH; Kaminsky, LS	1
Antiga, G; Battini, G; Fabbri, C; Ferrario, GM; Giordano, F; Meroni, M; Sessa, A; Volpi, A	1
Adachi, H; Chang, TH; Li, JM; Mori, N; Okuyama, T; Saito, I; Sun, XD; Zhang, KY	1
Adachi, H; Chang, TH; Mori, N; Okuyama, T; Saito, I	1
Blackshear, JL; Hammill, SC; Kopecky, SL; Litin, SC; Safford, RE	1
Hilleman, DE; Lucas, BD; Mohiuddin, SM; Stoysich, AM	1
Chetboul, V; Delisle, F; Devauchelle, P; Mai, W; Pouchelon, JL; Vial, V	1
Bove, AA; Davis, MJ; Sorrell, VL	1
Li, EK; Tam, LS	1
Cantrell, VE; Eckstein, J; Hall, SD; Hamman, MA; Jones, DR; Ring, BJ; Ruterbories, K; Williams, JA; Wrighton, SA	1
Christensen, H; Malterud, KE; Molden, E; Wangensteen, H	1
Molden, E; Westergren, T	1
Elston Lafata, J; Horn, JR; Kaatz, S; Raebel, MA; Schultz, L; Simpkins, J; Smith, DH; Yood, MU	1
Becker, RC; Berkowitz, SD; Breithardt, G; Fox, KAA; Halperin, JL; Hankey, GJ; Hellkamp, AS; Lokhnygina, Y; Mahaffey, KW; Nessel, CC; Patel, MR; Piccini, JP; Singer, DE; Washam, JB	1
Bando, Y; Ishii, H; Otori, K; Yokota, N	1
Ge, T; Song, EJ; Tang, S; Wang, J; Zhou, W; Zhu, Z	1
Borko, V; Gabričević, M; Kerep, R; Keser, T; Lauc, G; Šeba, T; Weitner, T	1

Reviews

4 review(s) available for diltiazem and warfarin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment. Mayo Clinic proceedings, 1996, Volume: 71, Issue:2 Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Catheter Ablation; Cerebrovascular Disorders; Diabetes Complications; Digoxin; Diltiazem; Embolism; Humans; Hypertension; Thromboembolism; Verapamil; Warfarin	1996
Current knowledge and significance of coronary artery ectasia: a chronologic review of the literature, recommendations for treatment, possible etiologies, and future considerations. Clinical cardiology, 1998, Volume: 21, Issue:3 Topics: Anticoagulants; Aspirin; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dilatation, Pathologic; Diltiazem; Humans; Incidence; Nitric Oxide; Platelet Aggregation Inhibitors; Warfarin	1998
[Interaction risk with statin switch]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2007, Feb-15, Volume: 127, Issue:4 Topics: Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Atorvastatin; Diltiazem; Drug Interactions; Drug Therapy, Combination; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Hemorrhages; Muscular Diseases; Pyrroles; Risk Factors; Simvastatin; Warfarin	2007

Trials

3 trial(s) available for diltiazem and warfarin

Article	Year
The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. The New England journal of medicine, 1992, Jul-09, Volume: 327, Issue:2 Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Humans; Hypertension, Pulmonary; Nifedipine; Prospective Studies; Pulmonary Artery; Survival Rate; Vascular Resistance; Warfarin	1992
Further elucidation of pharmacokinetic interaction between diltiazem and warfarin. International journal of clinical pharmacology and therapeutics, 1996, Volume: 34, Issue:2 Topics: Adult; Anticoagulants; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Drug Interactions; Humans; Liver; Male; Middle Aged; Protein Binding; Reference Values; Warfarin	1996
Efficacy and Safety of Rivaroxaban Versus Warfarin in Patients Taking Nondihydropyridine Calcium Channel Blockers for Atrial Fibrillation (from the ROCKET AF Trial). The American journal of cardiology, 2017, Aug-15, Volume: 120, Issue:4 Topics: Administration, Oral; Aged; Anticoagulants; Atrial Fibrillation; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Factor Xa Inhibitors; Female; Humans; Male; Risk Factors; Rivaroxaban; Stroke; Treatment Outcome; Verapamil; Warfarin	2017

Other Studies

32 other study(ies) available for diltiazem and warfarin

Article	Year
Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes. Journal of medicinal chemistry, 1998, Mar-26, Volume: 41, Issue:7 Topics: Absorption; Adsorption; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Permeability; Pharmacokinetics; Spectrophotometry, Ultraviolet	1998
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk). Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9 Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design. Journal of medicinal chemistry, 2020, 02-27, Volume: 63, Issue:4 Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry	2020
Case report of myocardial infarction in labor. American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:5 Pt 1 Topics: Adult; Anticoagulants; Diagnostic Errors; Diltiazem; Female; Humans; Myocardial Infarction; Obstetric Labor Complications; Pregnancy; Warfarin	1991
Selective inhibition of warfarin metabolism by diltiazem in humans. The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:1 Topics: Adult; Cytochrome P-450 Enzyme System; Diltiazem; Humans; Male; Metabolic Clearance Rate; Middle Aged; Stereoisomerism; Warfarin	1991
Acute renal failure due to hypersensitivity interstitial nephritis induced by warfarin sodium. Nephron, 1989, Volume: 52, Issue:2 Topics: Acute Kidney Injury; Aged; Diltiazem; Eosinophils; Female; Humans; Kidney Tubules; Myocardial Infarction; Nephritis; Nitroglycerin; Warfarin	1989
Effects of 3'-angeloyloxy-4'-acetoxy-3',4'-dihydroseselin on cardiohemodynamics in anesthetized dogs. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:6 Topics: Animals; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coumarins; Diltiazem; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Heart Rate; Male; Vascular Resistance	1994
Effects of a pyranocoumarin compound isolated from a Chinese medicinal plant on ischemic myocardial dysfunction in anesthetized dogs. European journal of pharmacology, 1994, Jun-02, Volume: 258, Issue:1-2 Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coumarins; Diltiazem; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Hemodynamics; Injections, Intravenous; Male; Myocardial Ischemia; Vascular Resistance	1994
Diagnosis of pulmonary thromboembolism in a cat using echocardiography and pulmonary scintigraphy. The Journal of small animal practice, 1997, Volume: 38, Issue:7 Topics: Animals; Anti-Bacterial Agents; Anticoagulants; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cat Diseases; Cats; Diltiazem; Doxycycline; Echocardiography; Heparin; Lung; Male; Pulmonary Artery; Pulmonary Embolism; Radiography, Thoracic; Radionuclide Imaging; Respiration; Warfarin	1997
Successful treatment with immunosuppression, anticoagulation and vasodilator therapy of pulmonary hypertension in SLE associated with secondary antiphospholipid syndrome. Lupus, 1998, Volume: 7, Issue:7 Topics: Adult; Anticoagulants; Antiphospholipid Syndrome; Cyclophosphamide; Diltiazem; Female; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Lupus Erythematosus, Systemic; Prednisone; Vasodilator Agents; Warfarin	1998
Comparative metabolic capabilities of CYP3A4, CYP3A5, and CYP3A7. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:8 Topics: Alprazolam; Aryl Hydrocarbon Hydroxylases; Biotransformation; Clarithromycin; Coumarins; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Cytochromes b5; Diltiazem; Estradiol; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Midazolam; Nifedipine; Tamoxifen; Testosterone; Triazolam	2002
Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel. European journal of clinical pharmacology, 2003, Volume: 58, Issue:10 Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Citrus paradisi; Coumarins; Cyclohexenes; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Flavonoids; Fruit; Furocoumarins; Humans; Limonene; Magnetic Resonance Spectroscopy; Plant Extracts; Terpenes	2003
Index of suspicion. Pediatrics in review, 2003, Volume: 24, Issue:12 Topics: Cardiac Catheterization; Child; Child, Preschool; Diagnosis, Differential; Diltiazem; Echocardiography; Humans; Hypokalemia; Male; Oxygen; Paralyses, Familial Periodic; Potassium; Seizures; Syncope; Tricuspid Valve Insufficiency; Tuberous Sclerosis; Warfarin	2003
What do medical records tell us about potentially harmful co-prescribing? Joint Commission journal on quality and patient safety, 2007, Volume: 33, Issue:7 Topics: Adult; Ambulatory Care; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diltiazem; Drug Interactions; Drug Utilization Review; Health Maintenance Organizations; Humans; Lovastatin; Medical Audit; Medication Errors; Office Visits; Polypharmacy; United States; Verapamil; Warfarin	2007
[Significant Prolongation of the International Normalized Ratio Associated with COVID-19 Treatment: Possible Drug Interaction with Remdesivir]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2022, Volume: 142, Issue:10 Topics: Adenosine Monophosphate; Alanine; Amiodarone; Anticoagulants; Atorvastatin; Bisoprolol; COVID-19 Drug Treatment; Dexamethasone; Diltiazem; Drug Interactions; Humans; International Normalized Ratio; Male; Middle Aged; Warfarin	2022
A rare cause of abdominal pain managed unconventionally: acute renal infarction caused by atrial fibrillation: a case report. Journal of medical case reports, 2022, Oct-19, Volume: 16, Issue:1 Topics: Abdominal Pain; Aged; Anticoagulants; Aspirin; Atrial Fibrillation; Clopidogrel; Diltiazem; Humans; Infarction; Male; Nitroglycerin; Platelet Aggregation Inhibitors; Thromboembolism; Thrombosis; Warfarin	2022
Potential Clinically Relevant Effects of Sialylation on Human Serum AAG-Drug Interactions Assessed by Isothermal Titration Calorimetry: Insight into Pharmacoglycomics? International journal of molecular sciences, 2023, May-09, Volume: 24, Issue:10 Topics: Calorimetry; Clindamycin; Diltiazem; Drug Interactions; Humans; Orosomucoid; Protein Binding; Thermodynamics; Warfarin	2023