diltiazem has been researched along with ticlopidine in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.50) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, M; Iso, T; Iwao, J; Kato, E; Kawashima, Y; Oya, M; Tabashi, K; Yamamoto, K | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Budriesi, R; Carosati, E; Chiarini, A; Chiu, FC; Cosimelli, B; Frosini, M; Fusi, F; Ioan, P; Katneni, K; Matucci, R; Micucci, M; Saponara, S; Severi, E; Spinelli, D | 1 |
| Hirano, T; Kanai, N; Nishio, S; Umetsu, T; Yamori, Y | 1 |
| Kienast, J; Verstraete, M | 1 |
| Bando, H; Tsubura, E; Yamashita, T | 1 |
| Karasawa, T; Katoh, M; Odawara, A; Sasaki, Y; Tamura, K | 1 |
| Doi, H; Kaburaki, M; Murata, S; Narita, H; Yasoshima, A | 1 |
| Katoh, M; Kikkawa, K; Odawara, A; Sasaki, Y; Shimazaki, T; Toryu, H | 1 |
| Ahn, YK; Bae, Y; Cho, JG; Cho, JH; Jeong, MH; Kang, JC; Kang, KT; Kim, KH; Kim, NH; Kim, SH; Lee, SH; Park, JC; Rhew, JY | 1 |
| Hashimoto, Y; Tashima, K; Uchino, M; Uyama, E; Yonehara, T | 1 |
| Doi, H; Karasawa, T; Katoh, M; Odawara, A | 1 |
| Chen, J; Dai, H; Qiu, Y; Tao, Q; Zhang, F; Zheng, L; Zhu, J | 1 |
| Frimerman, A; Lev-Ran, O; Locker, C; Mohr, R; Shaham, Y; Shapira, I; Uretzky, G | 1 |
| De Jonghe, B; Fangio, P; Lachérade, JC; Outin, H; Terville, JP | 1 |
| Lemley, CO; Wilson, ME | 1 |
5 review(s) available for diltiazem and ticlopidine
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors | 2012 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacology of the interaction between platelets and vessel wall.
Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Dextrans; Diltiazem; Dipyridamole; Epoprostenol; Humans; Imidazoles; Ketanserin; Piperidines; Pyrazoles; Pyrazolones; Sulfinpyrazone; Sulfonamides; Thiophenes; Ticlopidine | 1986 |
Comparison of bilateral thoracic artery grafting with percutaneous coronary interventions in diabetic patients.
Topics: Abciximab; Aged; Angioplasty, Balloon; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Combined Modality Therapy; Coronary Artery Bypass; Coronary Disease; Diabetes Complications; Diltiazem; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Isosorbide Dinitrate; Life Tables; Male; Middle Aged; Peptides; Platelet Aggregation Inhibitors; Recurrence; Retrospective Studies; Stents; Survival Analysis; Thoracic Arteries; Ticlopidine; Treatment Outcome; Vascular Patency | 2004 |
1 trial(s) available for diltiazem and ticlopidine
| Article | Year |
|---|---|
Effects of diltiazem on platelet activation and cytosolic calcium during percutaneous transluminal coronary angioplasty.
Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Calcium; Calcium Channel Blockers; Coronary Thrombosis; Cytosol; Diltiazem; Drug Therapy, Combination; Female; Humans; Male; P-Selectin; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Thromboxane B2; Ticlopidine | 2003 |
18 other study(ies) available for diltiazem and ticlopidine
| Article | Year |
|---|---|
Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Pulmonary Embolism; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thiazoles | 1988 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism.
Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Humans; Male; Microsomes, Liver; Myocytes, Cardiac; Oxadiazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazines; Vasodilator Agents | 2016 |
The effects of beraprost Na, a stable prostacyclin analog, on animal models of stroke.
Topics: Animals; Arachidonic Acid; Blood Pressure; Body Weight; Cerebrovascular Circulation; Cerebrovascular Disorders; Death, Sudden; Diltiazem; Epoprostenol; Male; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Inbred SHR; Ticlopidine | 1992 |
Effects of antiplatelet agents on pulmonary metastases.
Topics: Adenosine Diphosphate; Animals; Depression, Chemical; Diltiazem; Dipyridamole; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Platelet Aggregation; Thiophenes; Ticlopidine; Trapidil | 1984 |
Inhibitory effect of clentiazem (TA-3090) on platelet aggregation--alone and in combination with aspirin or ticlopidine.
Topics: Animals; Aspirin; Calcium Channel Blockers; Diltiazem; Drug Synergism; Drug Therapy, Combination; Humans; Male; Molecular Structure; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Ticlopidine | 1994 |
Antithrombotic effect of TA-993, a novel 1,5-benzothiazepine derivative, in conscious rats.
Topics: Administration, Oral; Animals; Antithrombins; Aspirin; Diltiazem; Dose-Response Relationship, Drug; Embolism; Male; Microscopy, Electron; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Thrombosis; Ticlopidine; Time Factors | 1995 |
Inhibitory effects of TA-993, a new 1,5-benzothiazepine derivative, on platelet aggregation.
Topics: Animals; Aspirin; Basilar Artery; Calcium; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrophysiology; Fibrinolytic Agents; Humans; Male; Mice; Platelet Aggregation; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Ticlopidine; Vasoconstriction | 1996 |
Successful management of intractable coronary spasm with a coronary stent.
Topics: Adult; Amlodipine; Aspirin; Calcium Channel Blockers; Cardiovascular Agents; Coronary Angiography; Coronary Artery Disease; Coronary Vasospasm; Diltiazem; Doxazosin; Drug Resistance; Drug Therapy, Combination; Ergonovine; Humans; Isosorbide Dinitrate; Male; Myocardial Infarction; Nicorandil; Nitrates; Pyridines; Stents; Ticlopidine; Ventricular Fibrillation | 2000 |
Susac's syndrome: beneficial effects of corticosteroid therapy in a Japanese case.
Topics: Adult; Anti-Inflammatory Agents; Asian People; Asthma; Ataxia; Brain; Cognition Disorders; Confusion; Diagnosis, Differential; Diltiazem; Drug Therapy, Combination; Hearing Loss, Bilateral; Hearing Loss, Sensorineural; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Multiple Sclerosis; Papilledema; Prednisone; Reflex, Abnormal; Retinal Artery; Retinal Artery Occlusion; Skin Diseases, Vascular; Syndrome; Ticlopidine; Vasculitis, Central Nervous System | 2001 |
Effects of the antiplatelet agent TA-993 and its metabolite MB3 on the hemorheological properties of rat and human erythrocytes.
Topics: Animals; Aspirin; Blood Viscosity; Diltiazem; Dose-Response Relationship, Drug; Erythrocytes; Hemolysis; Hemorheology; Humans; Phospholipids; Platelet Aggregation Inhibitors; Rats; Ticlopidine | 2001 |
Coronary spasm in a 59-yr-old woman with hyperventilation.
Topics: Alkalosis, Respiratory; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antihypertensive Agents; Aspirin; Cardiac Catheterization; Clopidogrel; Coronary Artery Disease; Coronary Vasospasm; Diagnosis, Differential; Diltiazem; Electrocardiography; Female; Heparin; Humans; Hyperventilation; Hyponatremia; Middle Aged; Platelet Aggregation Inhibitors; Schizophrenia; Ticlopidine; Water Intoxication | 2004 |
Effect of cytochrome P450 and aldo-keto reductase inhibitors on progesterone inactivation in primary bovine hepatic cell cultures.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Animals; Cattle; Cells, Cultured; Curcumin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dicumarol; Diltiazem; Enzyme Inhibitors; Female; Glucuronosyltransferase; Hepatocytes; Lactation; Liver; Naproxen; Progesterone; Ticlopidine | 2010 |