Page last updated: 2024-08-23

diltiazem and thromboxane a2

diltiazem has been researched along with thromboxane a2 in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (41.67)	18.7374
1990's	13 (54.17)	18.2507
2000's	1 (4.17)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Haught, WH; Lawson, DL; Mehta, JL; Yang, BC	1
Abbate, R; Boddi, M; Coppo, M; Gensini, GF; Neri Serneri, GG; Prisco, D; Rostagno, C	1
Feng, HF; Zhang, YH; Zhao, X	1
Buja, LM; Golino, P; McNatt, J; Willerson, JT; Yao, SK	1
Furui, H; Furumichi, T; Hayashi, H; Saito, H; Suzuki, T; Yamada, Y; Yamauchi, K; Yokota, M	1
Abbate, R; Boddi, M; Costanzo, G; Paniccia, R; Poggesi, L; Prisco, D; Rostagno, C	1
Francis, GS; Johnson, GJ; Leis, LA	1
Brunelli, C; Caponnetto, S; Galassi, AR; Hackett, D; Ianetti, M; Lipkin, D; Maseri, A; Patrono, C; Spallarossa, P; Vejar, M	1
Kito, M; Matsuura, T; Moriyama, T; Narita, H; Takamura, H; Tanaka, K	1
Hall, ED; Wolf, DL	1
Fulmor, IE; Grover, GJ	1
Corrigan, JJ; Fenster, PE; Ring, ME	2
Mehta, J; Mehta, P; Ostrowski, N	1
Hattori, R; Kawai, C; Sakaguchi, K; Susawa, T; Takatsu, Y; Yui, N; Yui, Y	1
Miwa, K; Toda, N	1
Honn, KV; Onoda, JM; Sloane, BF	1
Brigmon, L; Mehta, J; Mehta, P; Ostrowski, N	1
Kalsner, S	1
Hosoki, K; Karasawa, T; Kikuta, C; Yamamoto, T	1
Epstein, M; Hayashi, K; Loutzenhiser, R	1
Afzal, MN; Saeed, SA; Shah, BH	1
Cartier, R; Demers, P; Elkouri, S; Mathieu, P	1
Hanif, S; Khan, FL; Rahman, HB; Rahman, IH; Rasheed, H; Saeed, SA; Shah, BH; Shariff, AH	1

Trials

4 trial(s) available for diltiazem and thromboxane a2

Article	Year
[Drug modulation of thromboxane A2/prostacyclin balance and lipid peroxidation in patients with coronary artery disease]. Zhonghua nei ke za zhi, 1990, Volume: 29, Issue:8 Topics: Aged; Aspirin; Coronary Disease; Diltiazem; Epoprostenol; Female; Humans; Lipid Peroxidation; Male; Middle Aged; Superoxide Dismutase; Thromboxane A2	1990
Effects of calcium channel blockers on platelet aggregation and thromboxane A2 formation: an in vivo double blind randomized study. Thrombosis research, 1990, Aug-01, Volume: 59, Issue:3 Topics: Adult; Blood Platelets; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Humans; Male; Middle Aged; Nifedipine; Platelet Aggregation; Thromboxane A2; Verapamil	1990
Comparison of low-dose aspirin and coronary vasodilators in acute unstable angina. Circulation, 1990, Volume: 81, Issue:1 Suppl Topics: Angina Pectoris; Angina, Unstable; Aspirin; Diltiazem; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Platelet Aggregation; Randomized Controlled Trials as Topic; Thromboxane A2; Thromboxane B2	1990
Antiplatelet effects of oral diltiazem, propranolol, and their combination. British journal of clinical pharmacology, 1987, Volume: 24, Issue:5 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adult; Diltiazem; Drug Interactions; Epinephrine; Humans; Male; Platelet Aggregation Inhibitors; Propranolol; Thromboxane A2	1987

Other Studies

20 other study(ies) available for diltiazem and thromboxane a2

Article	Year
Slow channel calcium blockers attenuate reoxygenation-mediated vascular contraction, but augment anoxia-mediated vascular contraction. Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:5 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta; Diltiazem; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxygen; Oxyhemoglobins; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Inbred Strains; Thromboxane A2; Vasoconstriction; Verapamil	1992
In vitro effects of two novel calcium antagonists (nitrendipine and nisoldipine) on intraplatelet calcium redistribution, platelet aggregation and thromboxane A2 formation. Comparison with diltiazem, nifedipine and verapamil. Thrombosis research, 1991, Aug-15, Volume: 63, Issue:4 Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Diltiazem; Female; Humans; In Vitro Techniques; Male; Nifedipine; Nisoldipine; Nitrendipine; Platelet Aggregation; Thromboxane A2; Thromboxane B2; Verapamil	1991
Failure of nitroglycerin and diltiazem to reduce platelet-mediated vasoconstriction in dogs with coronary artery stenosis and endothelial injury: further evidence for thromboxane A2 and serotonin as mediators of coronary artery vasoconstriction in vivo. Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3 Topics: Animals; Blood Platelets; Coronary Disease; Coronary Vessels; Diltiazem; Dogs; Endothelium, Vascular; Hemodynamics; Nitroglycerin; Platelet Aggregation; Serotonin; Thromboxane A2; Vasoconstriction	1990
Inhibitory effects of endothelial cells and calcium channel blockers on platelet aggregation. Japanese heart journal, 1990, Volume: 31, Issue:2 Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aspirin; Blood Platelets; Bone Marrow Cells; Calcium Channel Blockers; Collagen; Diltiazem; Endothelium, Vascular; Epoprostenol; Fibroblasts; Humans; Nicardipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Verapamil	1990
Adenosine potentiates the inhibitory effects of calcium channel antagonists on human platelet aggregation induced by thromboxane A2 or U46619. Thrombosis research, 1990, Jul-01, Volume: 59, Issue:1 Topics: Adenosine; Alprostadil; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epinephrine; Humans; In Vitro Techniques; Nifedipine; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Thromboxane A2; Verapamil	1990
Dihydropyridine-sensitive and insensitive Ca2+ channels in human platelets. Journal of biochemistry, 1988, Volume: 104, Issue:6 Topics: Blood Platelets; Calcium Channels; Collagen; Diltiazem; Humans; In Vitro Techniques; Nifedipine; Thromboxane A2	1988
A pharmacological analysis of the pathophysiological mechanisms of posttraumatic spinal cord ischemia. Journal of neurosurgery, 1986, Volume: 64, Issue:6 Topics: Animals; Benzofurans; Calcium Channel Blockers; Cats; Cyclooxygenase Inhibitors; Diltiazem; Dinoprost; Epoprostenol; Female; Ibuprofen; Ischemia; Male; Meclofenamic Acid; Nifedipine; Prostaglandin Antagonists; Prostaglandins F; Spinal Cord; Thromboxane A2; Verapamil; Vitamin E	1986
Thromboxane A2 antagonist and diltiazem-induced enhancement of contractile function: the effect of timing of treatment. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:2 Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Coronary Circulation; Diltiazem; Dogs; Fatty Acids, Unsaturated; Hemodynamics; Hydrazines; Myocardial Contraction; Perfusion; Thromboxane A2; Time Factors	1988
Calcium blocker diltiazem inhibits platelet activation and stimulates vascular prostacyclin synthesis. The American journal of the medical sciences, 1986, Volume: 291, Issue:1 Topics: Benzazepines; Blood Platelets; Diltiazem; Epoprostenol; Humans; Platelet Aggregation; Thromboxane A2; Umbilical Veins	1986
Thromboxane A2 analogue induced coronary artery vasoconstriction in the rabbit. Cardiovascular research, 1987, Volume: 21, Issue:2 Topics: Animals; Calcium; Coronary Angiography; Coronary Vasospasm; Diltiazem; Dose-Response Relationship, Drug; Rabbits; Thromboxane A2	1987
Effects of oral diltiazem on platelet function: alone and in combination with "low dose" aspirin. Thrombosis research, 1986, Nov-01, Volume: 44, Issue:3 Topics: Adenosine Diphosphate; Adenosine Triphosphate; Administration, Oral; Aspirin; Bleeding Time; Blood Platelets; Diltiazem; Epinephrine; Humans; Male; Platelet Aggregation; Thromboxane A2	1986
The regional difference of relaxations induced by various vasodilators in isolated dog coronary and mesenteric arteries. Japanese journal of pharmacology, 1985, Volume: 38, Issue:3 Topics: Adenosine; Alprostadil; Animals; Coronary Vessels; Diltiazem; Dogs; Epoprostenol; Female; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Thromboxane A2; Vasodilator Agents	1985
Antithrombogenic effects of calcium channel blockers: synergism with prostacyclin and thromboxane synthase inhibitors. Thrombosis research, 1984, Jun-01, Volume: 34, Issue:5 Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epoprostenol; Humans; Nicotinic Acids; Nifedipine; Nimodipine; Oxidoreductases; Platelet Aggregation; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Verapamil	1984
Inhibitory effects of diltiazem on platelet activation caused by ionophore A23187 plus ADP or epinephrine in subthreshold concentrations. The Journal of laboratory and clinical medicine, 1983, Volume: 102, Issue:3 Topics: Adenosine Diphosphate; Adult; Benzazepines; Calcimycin; Calcium Chloride; Diltiazem; Epinephrine; Epoprostenol; Humans; Platelet Aggregation; Thromboxane A2; Thromboxane B2	1983
Non-neurogenic contractions in isolated coronary arteries by brief electrical pulses. Cardiovascular research, 1994, Volume: 28, Issue:12 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Cattle; Coronary Vessels; Diltiazem; Electric Stimulation; In Vitro Techniques; Insecticides; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Prostaglandin Endoperoxides, Synthetic; Pyrethrins; Ryanodine; Thromboxane A2; Vasoconstrictor Agents	1994
Preventive effect of monatepil on thromboxane A2 agonist-induced myocardial ischemia in rats. Arzneimittel-Forschung, 1994, Volume: 44, Issue:6 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Blood Pressure; Calcium Channel Blockers; Dibenzothiepins; Diltiazem; Electrocardiography; Heart Rate; Male; Myocardial Ischemia; Myocardium; Oxygen Consumption; Piperazines; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vasoconstrictor Agents	1994
Direct evidence that thromboxane mimetic U44069 preferentially constricts the afferent arteriole. Journal of the American Society of Nephrology : JASN, 1997, Volume: 8, Issue:1 Topics: Animals; Arterioles; Bridged Bicyclo Compounds, Heterocyclic; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydrazines; In Vitro Techniques; Kidney Glomerulus; Male; Nifedipine; Prostaglandin Endoperoxides, Synthetic; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane; Thromboxane A2; Vasoconstriction	1997
Dual effects of nimesulide, a COX-2 inhibitor, in human platelets. Life sciences, 1998, Volume: 63, Issue:20 Topics: Blood Platelets; Calcium Channel Blockers; Cyclooxygenase Inhibitors; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Epinephrine; Humans; Nitric Oxide Donors; Penicillamine; Platelet Aggregation; Platelet Aggregation Inhibitors; Sulfonamides; Thromboxane A2; Verapamil	1998
[The vasoconstrictor effect of cyclosporine on the pulmonary vein is mediated by its vehicle: the cremophor]. Annales de chirurgie, 1998, Volume: 52, Issue:8 Topics: Animals; Bicyclic Monoterpenes; Calcium Channel Blockers; Calcium Channels; Cyclooxygenase Inhibitors; Cyclosporine; Diltiazem; Dogs; Immunosuppressive Agents; Indomethacin; Isometric Contraction; Muscle, Smooth, Vascular; Pharmaceutical Vehicles; Polyethylene Glycols; Pulmonary Veins; Thromboxane A2; Vasoconstriction; Vasodilator Agents	1998
Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine. Experimental & molecular medicine, 2001, Dec-31, Volume: 33, Issue:4 Topics: Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Estrenes; Flavonoids; Humans; In Vitro Techniques; Indomethacin; Kinetics; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet Activating Factor; Platelet Activation; Platelet Aggregation; Pyrrolidinones; Serotonin; Thromboxane A2; Verapamil	2001