Page last updated: 2024-08-23

diltiazem and sq-11725

diltiazem has been researched along with sq-11725 in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19904 (21.05)18.7374
1990's1 (5.26)18.2507
2000's8 (42.11)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Akamatsu, M1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Hartwell, BL; Mark, JB1
Crawford, MH; Miller, WE; O'Rourke, RA; Vittitoe, J1
Schwartz, A; Smith, R1
Hess, DS; Scheinman, MM1
Taylor, SH1
Zimmers, T1
Leung, TK; Nattel, S; Rivard, L; Schram, G; Shiroshita-Takeshita, A; Sinno, H1

Reviews

2 review(s) available for diltiazem and sq-11725

ArticleYear
New antiarrhythmic drugs.
    American journal of surgery, 1983, Volume: 145, Issue:6

    Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half-Life; Humans; Hypertension; Lidocaine; Metoprolol; Nadolol; Nifedipine; Propanolamines; Propranolol; Tocainide; Verapamil

1983
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994

Trials

2 trial(s) available for diltiazem and sq-11725

ArticleYear
Nadolol versus diltiazem and combination for preventing exercise-induced ischemia in severe angina pectoris.
    The American journal of cardiology, 1988, Sep-01, Volume: 62, Issue:7

    Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Diltiazem; Electrocardiography; Female; Heart; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Nadolol; Physical Exertion

1988
Usefulness of amlodipine for angina pectoris.
    The American journal of cardiology, 1994, Jan-27, Volume: 73, Issue:3

    Topics: Amlodipine; Angina Pectoris; Angina Pectoris, Variant; Cardiac Output; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise; Humans; Male; Myocardial Ischemia; Nadolol; Randomized Controlled Trials as Topic

1994

Other Studies

16 other study(ies) available for diltiazem and sq-11725

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Combinations of beta-blockers and calcium channel blockers: a cause of malignant perioperative conduction disturbances?
    Anesthesia and analgesia, 1986, Volume: 65, Issue:8

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Artery Bypass; Diltiazem; Drug Therapy, Combination; Humans; Male; Middle Aged; Nadolol; Nifedipine; Postoperative Complications; Propanolamines

1986
Diltiazem prophylaxis in refractory migraine.
    The New England journal of medicine, 1984, May-17, Volume: 310, Issue:20

    Topics: Adrenergic beta-Antagonists; Adult; Benzazepines; Diltiazem; Female; Humans; Male; Middle Aged; Migraine Disorders; Nadolol; Pilot Projects; Propanolamines

1984
Cases in electrocardiography.
    The American journal of emergency medicine, 2000, Volume: 18, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Diagnosis, Differential; Diltiazem; Electrocardiography; Emergency Treatment; Female; Heart Block; Humans; Male; Multiple Trauma; Nadolol; Pain; Recurrence

2000
The pharmacological response of ischemia-related atrial fibrillation in dogs: evidence for substrate-specific efficacy.
    Cardiovascular research, 2007, Apr-01, Volume: 74, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Coronary Disease; Diltiazem; Dogs; Electric Stimulation; Flecainide; Models, Animal; Nadolol; Phenethylamines; Potassium Channel Blockers; Refractory Period, Electrophysiological; Sodium Channel Blockers; Sulfonamides; Vagus Nerve

2007