Compounds > diltiazem
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diltiazem and sildenafil citrate

diltiazem has been researched along with sildenafil citrate in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (66.67)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Khoury, V; Kritharides, L1
Howes, L1
Martin, J1
Feely, J; Hennessy, M; Mahmud, A1
Akaishi, Y; Hattori, Y; Kitabatake, A; Sakuma, I; Sato, A; Tomioka, H1
Ang, PS; Su, DH; Tow, SL1
Farquhar, D; Kim, RB; Mehta, S; Skeith, L; Yamashita, C1
Berk-Krauss, J; Christman, MP; Franks, A; Liebman, TN; Sicco, KL1

Trials

1 trial(s) available for diltiazem and sildenafil citrate

ArticleYear
Effect of sildenafil on blood pressure and arterial wave reflection in treated hypertensive men.
    Journal of human hypertension, 2001, Volume: 15, Issue:10

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Diltiazem; Diuretics; Drug Interactions; Erectile Dysfunction; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nitric Oxide; Phosphodiesterase Inhibitors; Piperazines; Pulsatile Flow; Purines; Receptors, Angiotensin; Sildenafil Citrate; Single-Blind Method; Sulfones

2001

Other Studies

8 other study(ies) available for diltiazem and sildenafil citrate

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
    Australian and New Zealand journal of medicine, 2000, Volume: 30, Issue:5

    Topics: Aged; Angina Pectoris; Coronary Angiography; Diltiazem; Humans; Hypotension; Male; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2000
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
    Internal medicine journal, 2001, Volume: 31, Issue:6

    Topics: Aged; Cardiac Catheterization; Cardiovascular Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Erectile Dysfunction; Humans; Hypotension; Male; Mixed Function Oxygenases; Nitrates; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2001
Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension.
    Internal medicine journal, 2001, Volume: 31, Issue:6

    Topics: Cardiovascular Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Diltiazem; Drug Interactions; Humans; Hypotension; Mixed Function Oxygenases; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2001
Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery.
    European journal of pharmacology, 2002, Feb-22, Volume: 437, Issue:3

    Topics: Animals; Celiprolol; Coronary Vessels; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Nicorandil; Nitroprusside; Pinacidil; Piperazines; Propanolamines; Purines; Sildenafil Citrate; Sulfones; Swine; Vasodilation; Vasodilator Agents

2002
Bilateral posterior ischemic optic neuropathy associated with use of sildenafil.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2008, Volume: 28, Issue:1

    Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Atenolol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drugs, Chinese Herbal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypotension; Male; Optic Nerve; Optic Neuropathy, Ischemic; Phosphodiesterase Inhibitors; Piperazines; Purines; Retinal Artery; Risk Factors; Sildenafil Citrate; Simvastatin; Sulfones; Vision, Low

2008
Sildenafil and furosemide associated ototoxicity: consideration of drug-drug interactions, synergy, and broader clinical relevance.
    Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2013, Volume: 20, Issue:2

    Topics: Aged; Canada; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Diltiazem; Diuretics; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Enzyme Inhibitors; Furosemide; Hearing Loss; Humans; Hypertension, Pulmonary; Male; Phosphodiesterase 5 Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones

2013
Botulinum toxin for treatment of Raynaud phenomenon in CREST syndrome.
    Dermatology online journal, 2018, Dec-15, Volume: 24, Issue:12

    Topics: Acetylcholine Release Inhibitors; Administration, Topical; Aged; Botulinum Toxins; CREST Syndrome; Diltiazem; Female; Humans; Nitroglycerin; Pain; Raynaud Disease; Sildenafil Citrate; Treatment Failure; Ulcer; Vasodilator Agents

2018