Page last updated: 2024-08-23

diltiazem and reserpine

diltiazem has been researched along with reserpine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19905 (22.73)18.7374
1990's4 (18.18)18.2507
2000's5 (22.73)29.6817
2010's8 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Globisch, C; Kassack, MU; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Müller, H; Pick, A; Wiese, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
London, RE; Murphy, E; Norris, TA; Steenbergen, C; Watts, JA1
Atkinson, J; Capdeville-Atkinson, C; Fouda, AK; Henrion, D; Kaufmann, A; Thorin, E1
Crosland, RD1
Miller, RC; Schoeffter, P1
Frances, H; Renwart, N; Simon, P1
Ban, M; Ito, T; Kobayashi, T; Ogawa, K; Suzuki, Y; Watanabe, T; Yamazaki, N1
Alegría, E; Arcas, R; Barba, J; Llorens, R; Malpartida, F; Martín Trenor, A1
Chakrabarti, P; Choudhuri, BS; Sen, S1
Ghosh, B; Reddy, LH1
Modirrousta, M; Tachere, RO1

Reviews

2 review(s) available for diltiazem and reserpine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Treatment of coronary arterial spasm].
    Revista de medicina de la Universidad de Navarra, 1982, Volume: 26, Issue:2

    Topics: Amiodarone; Coronary Vasospasm; Denervation; Diltiazem; Humans; Isosorbide Dinitrate; Myocardial Revascularization; Nifedipine; Nitroglycerin; Phenoxybenzamine; Phentolamine; Reserpine; Verapamil

1982

Trials

1 trial(s) available for diltiazem and reserpine

ArticleYear
Diltiazem for treatment of essential hypertension: a double-blind controlled study with reserpine.
    Clinical therapeutics, 1984, Volume: 6, Issue:6

    Topics: Adult; Aged; Benzazepines; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Reserpine

1984

Other Studies

19 other study(ies) available for diltiazem and reserpine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
New functional assay of P-glycoprotein activity using Hoechst 33342.
    Bioorganic & medicinal chemistry, 2007, Dec-01, Volume: 15, Issue:23

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluoresceins; Humans; Microscopy, Fluorescence; Molecular Structure; Principal Component Analysis; Time Factors

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
    Bioorganic & medicinal chemistry, 2008, Sep-01, Volume: 16, Issue:17

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of diltiazem on lactate, ATP, and cytosolic free calcium levels in ischemic hearts.
    Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:1

    Topics: Adenosine Triphosphate; Animals; Calcium; Catecholamines; Coronary Disease; Cytosol; Diltiazem; Heart; Heart Rate; Lactates; Male; Myocardium; Rats; Rats, Inbred Strains; Reserpine

1990
The role of endogenous norepinephrine release in potassium-evoked vasoconstriction of the rat tail artery.
    European journal of pharmacology, 1991, Nov-19, Volume: 205, Issue:1

    Topics: Animals; Arteries; Calcium; Chromatography, High Pressure Liquid; Diltiazem; Electric Stimulation; Electrochemistry; Male; Norepinephrine; Perfusion; Phentolamine; Potassium; Rats; Rats, Inbred Strains; Reserpine; Tail; Vasoconstrictor Agents

1991
Effect of drugs on the lethality in mice of the venoms and neurotoxins from sundry snakes.
    Toxicon : official journal of the International Society on Toxinology, 1991, Volume: 29, Issue:6

    Topics: Animals; Dexamethasone; Diltiazem; Female; Lethal Dose 50; Mice; Mice, Inbred ICR; Neuromuscular Depolarizing Agents; Neurotoxins; Nicergoline; Nifedipine; Piperidines; Piracetam; Primaquine; Reserpine; Snake Venoms; Snakes; Verapamil

1991
Role of sodium-calcium exchange and effects of calcium entry blockers on endothelial-mediated responses in rat isolated aorta.
    Molecular pharmacology, 1986, Volume: 30, Issue:1

    Topics: Amiloride; Animals; Aorta; Bepridil; Calcium; Calcium Channel Blockers; Choline; Cyclic GMP; Diltiazem; Endothelium; Female; Lithium; Muscle, Smooth, Vascular; Nicergoline; Nifedipine; Pyrrolidines; Rats; Rats, Inbred Strains; Reserpine; Sodium; Verapamil

1986
The calcium entry blockers: anti-manic drugs?
    Progress in neuro-psychopharmacology & biological psychiatry, 1986, Volume: 10, Issue:6

    Topics: Amphetamines; Animals; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Oxolinic Acid; Reserpine; Verapamil

1986
Isoniazid accumulation in Mycobacterium smegmatis is modulated by proton motive force-driven and ATP-dependent extrusion systems.
    Biochemical and biophysical research communications, 1999, Mar-24, Volume: 256, Issue:3

    Topics: Adenosine Triphosphate; Antitubercular Agents; Biological Transport, Active; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Diltiazem; Drug Resistance, Microbial; Hydrogen-Ion Concentration; Ionophores; Isoniazid; Mycobacterium smegmatis; Nifedipine; Nigericin; Proton-Motive Force; Reserpine; Uncoupling Agents; Valinomycin; Vanadates; Verapamil

1999
Effect of physicochemical parameters on skin permeability of antihypertensive.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:7

    Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Atenolol; Chemical Phenomena; Chemistry, Physical; Diltiazem; Female; In Vitro Techniques; Mice; Permeability; Prazosin; Propranolol; Reserpine; Skin

2001
Beyond anxiety and agitation: A clinical approach to akathisia.
    Australian family physician, 2017, Volume: 46, Issue:5

    Topics: Adult; Antidepressive Agents; Antiemetics; Antipsychotic Agents; Anxiety; Buspirone; Cinnarizine; Diltiazem; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Methyldopa; Psychomotor Agitation; Reserpine; Suicidal Ideation

2017