Page last updated: 2024-08-23

diltiazem and ranolazine

diltiazem has been researched along with ranolazine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's4 (33.33)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Dalvie, D; Loi, CM; Smith, DA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bouvy, T; Cheron, P; Cocco, G; Detry, JM; Pouleur, H; Rousseau, MF; Williams, G1
Eadie, J; Herron, WJ; Liu, Y; Penman, AD; Reilly, MA; Rush, WR1
Chaitman, BR; Chumakova, G; Kuch, J; Parker, JO; Pepine, CJ; Skettino, SL; Skopal, J; Wang, W; Wolff, AA1
Gratsianskiĭ, NA1
Abdallah, H; Chu, N; Huan, BL; Hussein, Z; Jerling, M; Leung, K1
Rifkin, SI1
Gitman, M; Hazzan, A; Jhaveri, KD; Patni, H1
Mittal, SR1
Bosco, B; D'Andrea, D; Di Chiara, G; Iodice, P; Uran, C1

Reviews

1 review(s) available for diltiazem and ranolazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for diltiazem and ranolazine

ArticleYear
Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem.
    Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:1

    Topics: Acetanilides; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Angina Pectoris; Blood Pressure; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Piperazines; Ranolazine

1992
Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial.
    JAMA, 2004, Jan-21, Volume: 291, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Aged; Amlodipine; Angina Pectoris; Atenolol; Calcium Channel Blockers; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Ischemia; Nitroglycerin; Physical Exertion; Piperazines; Ranolazine; Survival Analysis

2004
Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects.
    Journal of clinical pharmacology, 2005, Volume: 45, Issue:4

    Topics: Acetanilides; Adolescent; Adult; Diltiazem; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Ketoconazole; Male; Middle Aged; Piperazines; Ranolazine; Simvastatin

2005

Other Studies

8 other study(ies) available for diltiazem and ranolazine

ArticleYear
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
The characterization of the metabolites of ranolazine in man by liquid chromatography mass spectrometry.
    Rapid communications in mass spectrometry : RCM, 1995, Volume: 9, Issue:14

    Topics: Acetanilides; Animals; Chromatography, High Pressure Liquid; Diltiazem; Glucuronates; Humans; Indicators and Reagents; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Piperazines; Ranolazine; Rats

1995
[Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina. Results of CARISA].
    Kardiologiia, 2004, Volume: 44, Issue:3

    Topics: Acetanilides; Adrenergic beta-Antagonists; Amlodipine; Angina Pectoris; Atenolol; Cardiovascular Agents; Chronic Disease; Diltiazem; Double-Blind Method; Exercise Test; Humans; Multicenter Studies as Topic; Piperazines; Placebos; Randomized Controlled Trials as Topic; Ranolazine; Time Factors; Vasodilator Agents

2004
Multiple drug interactions in a renal transplant patient leading to simvastatin-induced rhabdomyolysis: a case report.
    Medscape journal of medicine, 2008, Volume: 10, Issue:11

    Topics: Acetanilides; Adrenergic alpha-Antagonists; Calcium Channel Blockers; Carbazoles; Carvedilol; Diltiazem; Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Transplantation; Male; Middle Aged; Piperazines; Propanolamines; Ranolazine; Rhabdomyolysis; Simvastatin

2008
Ranolazine, tacrolimus, and diltiazem might be a hazardous combination in a transplant patient.
    Renal failure, 2012, Volume: 34, Issue:2

    Topics: Acetanilides; Acute Kidney Injury; Calcium Channel Blockers; Diltiazem; Drug Interactions; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Piperazines; Postoperative Complications; Ranolazine; Tacrolimus

2012
Slow junctional rhythm, QTc prolongation and transient torsades de-pointes following combined use of Ivabradine, Diltiazem and Ranolazine.
    The Journal of the Association of Physicians of India, 2014, Volume: 62, Issue:5

    Topics: Acetanilides; Aged, 80 and over; Angina, Unstable; Benzazepines; Bradycardia; Diltiazem; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Electrocardiography; Female; Humans; Ivabradine; Long QT Syndrome; Piperazines; Ranolazine; Torsades de Pointes

2014
A case of vasospastic angina. Vasospasm physiopathology: a new therapeutic role for ranolazine?
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020, Aug-03, Volume: 90, Issue:3

    Topics: Adult; Aftercare; Angina Pectoris, Variant; Calcium Channel Blockers; Coronary Angiography; Coronary Vasospasm; Diltiazem; Drug Therapy, Combination; Echocardiography; Humans; Male; Ranolazine; Recurrence; Sodium Channel Blockers; Treatment Outcome

2020