Page last updated: 2024-08-23

diltiazem and quinidine

diltiazem has been researched along with quinidine in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	10 (18.87)	18.7374
1990's	7 (13.21)	18.2507
2000's	18 (33.96)	29.6817
2010's	17 (32.08)	24.3611
2020's	1 (1.89)	2.80

Authors

Authors	Studies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Keserü, GM	1
Nagashima, R; Nishikawa, T; Tobita, M	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Jia, L; Sun, H	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Cooper, J; Cui, Y; Fink, M; Gavaghan, DJ; Heath, BM; McMahon, NC; Mirams, GR; Noble, D; Sher, A	1
Balani, SK; Gan, LS; Li, P; Lu, C	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Dalvie, D; Loi, CM; Smith, DA	1
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Budriesi, R; Carosati, E; Chiarini, A; Chiu, FC; Cosimelli, B; Frosini, M; Fusi, F; Ioan, P; Katneni, K; Matucci, R; Micucci, M; Saponara, S; Severi, E; Spinelli, D	1
Narimatsu, A; Taira, N	1
Farrugia, G; Rae, JL	1
Hunt, CM; Stave, GM; Westerkam, WR	1
Nattel, S; Nayebpour, M	1
Boucher, M; Dubray, C; Duchêne-Marullaz, P	1
Bazill, GW; Dexter, TM	1
Cornwell, MM; Gottesman, MM; Pastan, I	1
Gonzalez-Sicilia, L; Hernandez, J; Laorden, ML; Perez, D; Villalobos, JP	1
Anda, L; Eichelbaum, M; Greenblatt, DJ; Ochs, HR	1
Hardy, MA; Ware, HM	1
Bender, F; Gülker, H; Heuer, H; Thale, J	1
Fujita, M; Ito, K; Owada, E; Yoshida, A	1
Bendeer, F; Gülker, H; Heuer, H; Meyer, M; Thale, J; Weiss, U	1
Chiang, BN; Hong, CY	1
Carignan, G; Carrier, K; Laganière, S; Lessard, M	1
Carignan, G; Carrier, K; Davies, RF; Foris, K; Goernert, L; Laganière, S; McGilveray, I; Pereira, C	1
Armstrong, JD; Kaiser, K; Rosay, P; Wang, Z	1
Binder, G; Chang, LF; Davis, BM; Dropulic, B; Humeau, L; Korshalla, L; Lu, X; Ni, Y; Ogunjimi, EO; Slepushkin, V	1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H	1

Reviews

1 review(s) available for diltiazem and quinidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

2 trial(s) available for diltiazem and quinidine

Article	Year
Diltiazem, verapamil, and quinidine in patients with chronic atrial fibrillation. Journal of clinical pharmacology, 1985, Volume: 25, Issue:3 Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Benzazepines; Chronic Disease; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinidine; Random Allocation; Verapamil	1985
Pharmacokinetic and pharmacodynamic interactions between diltiazem and quinidine. Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3 Topics: Adult; Analysis of Variance; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Drug Interactions; Half-Life; Humans; Male; Quinidine; Reference Values; Time Factors; Vasodilator Agents	1996

Article

Year

Diltiazem, verapamil, and quinidine in patients with chronic atrial fibrillation.

Journal of clinical pharmacology, 1985, Volume: 25, Issue:3

Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Benzazepines; Chronic Disease; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Female; Humans; Male; Middle Aged; Quinidine; Random Allocation; Verapamil

1985

Pharmacokinetic and pharmacodynamic interactions between diltiazem and quinidine.

Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3

Topics: Adult; Analysis of Variance; Anti-Arrhythmia Agents; Antihypertensive Agents; Area Under Curve; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Drug Interactions; Half-Life; Humans; Male; Quinidine; Reference Values; Time Factors; Vasodilator Agents

1996

Other Studies

50 other study(ies) available for diltiazem and quinidine

Article	Year
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs. Journal of medicinal chemistry, 1985, Volume: 28, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium	1985
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Rational use of in vitro P-glycoprotein assays in drug discovery. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16 Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship	2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors. Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11 Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Support vector machines classification of hERG liabilities based on atom types. Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11 Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk. Cardiovascular research, 2011, Jul-01, Volume: 91, Issue:1 Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dogs; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; HEK293 Cells; Humans; Ion Channels; Kinetics; Models, Cardiovascular; NAV1.5 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Potassium Channel Blockers; Rabbits; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sodium Channels; Torsades de Pointes; Transfection	2011
A refined cytochrome P540 IC₅₀ shift assay for reliably identifying CYP3A time-dependent inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:6 Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; Inhibitory Concentration 50; Microsomes, Liver; Time Factors	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Which metabolites circulate? Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5 Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations	2013
MICE models: superior to the HERG model in predicting Torsade de Pointes. Scientific reports, 2013, Volume: 3 Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Understanding Oxadiazolothiazinone Biological Properties: Negative Inotropic Activity versus Cytochrome P450-Mediated Metabolism. Journal of medicinal chemistry, 2016, Apr-14, Volume: 59, Issue:7 Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Guinea Pigs; Heart Atria; Humans; Male; Microsomes, Liver; Myocytes, Cardiac; Oxadiazoles; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazines; Vasodilator Agents	2016
Effects of atrio-ventricular conduction of calcium-antagonistic coronary vasodilators, local anaesthetics and quinidine injected into the posterior and the anterior septal artery of the atrio-ventricular node preparation of the dog. Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 294, Issue:2 Topics: Action Potentials; Anesthetics, Local; Animals; Atrioventricular Node; Benzazepines; Calcium; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Female; Heart Conduction System; In Vitro Techniques; Injections; Lidocaine; Male; Neural Conduction; Nifedipine; Procaine; Quinidine; Vasodilator Agents; Verapamil	1976
Whole-cell potassium current in rabbit corneal epithelium activated by fenamates. The Journal of membrane biology, 1992, Volume: 129, Issue:1 Topics: Animals; Barium; Cornea; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Ion Channel Gating; Membrane Potentials; ortho-Aminobenzoates; Potassium Channels; Quinidine; Rabbits	1992
Effect of age and gender on the activity of human hepatic CYP3A. Biochemical pharmacology, 1992, Jul-22, Volume: 44, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diltiazem; Humans; Lidocaine; Microsomes, Liver; Middle Aged; Nifedipine; Oxidoreductases, N-Demethylating; Quinidine; Sex Factors; Smoking	1992
Pharmacologic response of cesium-induced ventricular tachyarrhythmias in anesthetized dogs. Journal of cardiovascular pharmacology, 1990, Volume: 15, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cesium; Chlorides; Chromatography, High Pressure Liquid; Diltiazem; Dogs; Electric Stimulation; Electrocardiography; Female; Heart Ventricles; Isoproterenol; Lidocaine; Magnesium Chloride; Male; Quinidine; Sodium Channels; Vagus Nerve	1990
Effects of bepridil, diltiazem and verapamil on atrial refractoriness and heart rate in the conscious dog: comparison with quinidine. General pharmacology, 1991, Volume: 22, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Atrial Function, Right; Bepridil; Blood Pressure; Diltiazem; Dogs; Female; Heart; Heart Rate; Male; Pressoreceptors; Quinidine; Tachycardia; Verapamil	1991
Role of endocytosis in the action of ether lipids on WEHI-3B, HL60, and FDCP-mix A4 cells. Cancer research, 1990, Dec-01, Volume: 50, Issue:23 Topics: Animals; Antineoplastic Agents; Azepines; Cell Survival; Chloroquine; Diltiazem; Drug Synergism; Endocytosis; Furans; Humans; Hydroxyzine; In Vitro Techniques; Leukemia, Myeloid; Mice; Nifedipine; Phospholipid Ethers; Platelet Activating Factor; Pyridines; Quinidine; Quinine; Sodium Fluoride; Thiazoles; Triazoles; Verapamil	1990
Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein. The Journal of biological chemistry, 1987, Feb-15, Volume: 262, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Carcinoma; Cell Line; Diltiazem; Drug Resistance; Glycoproteins; Humans; Nitrendipine; Quinidine; Verapamil; Vinblastine	1987
Compared efficacy of quinidine, amiodarone and diltiazem on both nomotopic and ectopic automaticity in the rat heart. Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:1 Topics: Amiodarone; Animals; Atrial Function; Diltiazem; Female; Heart Atria; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Quinidine; Rats; Rats, Inbred Strains; Ventricular Function	1987
Roles of Ca2+ and Na+ on the modulation of antidiuretic hormone action on urea permeability in toad urinary bladder. The Journal of clinical investigation, 1985, Volume: 75, Issue:3 Topics: Animals; Arginine Vasopressin; Bufo marinus; Calcimycin; Calcium; Carbachol; Cell Membrane Permeability; Diltiazem; Dinitrophenols; Female; Indomethacin; Iodoacetates; Iodoacetic Acid; Monensin; Quinidine; Sodium; Urea; Urinary Bladder	1985
[Enhancement of the antifibrillatory efficacy of quinidine in atrial fibrillation by verapamil (author's transl)]. Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:1 Topics: Animals; Atrial Fibrillation; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Diltiazem; Dogs; Drug Therapy, Combination; Electrocardiography; Female; Male; Quinidine; Verapamil	1982
Effects of diltiazem on plasma and tissue digoxin levels in mice. Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:8 Topics: Animals; Benzazepines; Blood Proteins; Digoxin; Diltiazem; Drug Interactions; Male; Mice; Mice, Inbred Strains; Protein Binding; Quinidine	1984
Effects of diltiazem on vulnerability to atrial and ventricular reentrant arrhythmias in the normal and ischemic heart. Arzneimittel-Forschung, 1983, Volume: 33, Issue:8 Topics: Animals; Arrhythmias, Cardiac; Benzazepines; Coronary Disease; Diltiazem; Dogs; Electrophysiology; Female; Male; Myocardial Infarction; Quinidine; Verapamil	1983
Local anaesthetic effect of antiarrhythmic drugs and human sperm immobilization: mechanism and application of the interrelationship. British journal of clinical pharmacology, 1984, Volume: 17, Issue:6 Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Diltiazem; Humans; Labetalol; Male; Mexiletine; Procainamide; Quinidine; Sperm Immobilizing Agents	1984
Simultaneous determination of diltiazem and quinidine in human plasma by liquid chromatography. Journal of chromatography. B, Biomedical applications, 1995, Oct-20, Volume: 672, Issue:2 Topics: Chromatography, High Pressure Liquid; Diltiazem; Humans; Hydrogen-Ion Concentration; Quality Control; Quinidine; Spectrometry, Fluorescence	1995
Synchronized neural activity in the Drosophila memory centers and its modulation by amnesiac. Neuron, 2001, Volume: 30, Issue:3 Topics: Aequorin; Age Factors; Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Signaling; Cell Membrane; Cobalt; Diltiazem; Drosophila; Drosophila Proteins; Enzyme Inhibitors; GABA Agonists; Genes, Reporter; Ionophores; Membrane Potentials; Memory; Muscimol; Mutation; Nervous System; Neurons; Neuropeptides; Nicotinic Agonists; Quinidine; Tetrodotoxin; Thapsigargin; Verapamil; Veratridine	2001
ABC transporter inhibitors that are substrates enhance lentiviral vector transduction into primitive hematopoietic progenitor cells. Blood, 2004, Jul-15, Volume: 104, Issue:2 Topics: Adult; Animals; Antigens, CD34; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Centrifugation; Diltiazem; Genetic Therapy; Genetic Vectors; HeLa Cells; Hematopoietic Stem Cells; Humans; Lentivirus; Mice; Mice, Inbred NOD; Mice, SCID; Quinidine; Transduction, Genetic; Verapamil	2004
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats. Pharmacology research & perspectives, 2021, Volume: 9, Issue:5 Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine	2021