Page last updated: 2024-08-23

diltiazem and prednisolone

diltiazem has been researched along with prednisolone in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (17.24)18.2507
2000's12 (41.38)29.6817
2010's12 (41.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Akamatsu, M1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bergström, C; Fellström, B; Frödin, L; Hanås, E; Skarp-Orberg, I; Wahlberg, J1
Carozzi, S; Fontana, I; Nasini, MG; Nocera, A; Pietrucci, A; Valente, U1
Becker, GJ; Choy, BY; Walker, RG1
Fassihi, R; Kim, H1
Imani, S; Jusko, WJ; Steiner, R1
Akhlaghi, F; Gleeson, M; McCaughan, G; McLachlan, AJ; Nelson, A; Zahir, H1
Akpinar, O; Aksoy, H; Ilgenli, TF; Söylemez, N; Yilmaz, R1
Ding, X; Fan, X; Feng, X; Hou, J; Pan, X; Qin, G; Song, Y; Tian, P; Tian, X; Xiang, H; Xue, W; Yan, H1
Atteno, M; Cantarini, L; Caso, F; Costa, L; Cozzi, F; Punzi, L; Scarpa, R; Sfriso, P1
Adeneye, AA; Akindele, AJ; Benebo, AS; Olatoye, F1
Akindele, AJ; Amagon, KI; Oludadepo, GO; Osiagwu, DD; Singh, D1

Reviews

1 review(s) available for diltiazem and prednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for diltiazem and prednisolone

ArticleYear
Diltiazem treatment with reduced dose of cyclosporine in renal transplant recipients.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Azathioprine; Creatinine; Cyclosporine; Diltiazem; Drug Administration Schedule; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Function Tests; Kidney Transplantation; Prednisolone; Prospective Studies

1992
Immunosuppressive effects of different calcium channel blockers in human kidney allografts.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Calcium; Calcium Channel Blockers; Cyclosporine; Cytokines; Diltiazem; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Isradipine; Kidney Transplantation; Lymphocytes; Prednisolone; Transplantation, Homologous; Verapamil

1995
Population pharmacokinetic estimation of tacrolimus apparent clearance in adult liver transplant recipients.
    Therapeutic drug monitoring, 2005, Volume: 27, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Algorithms; Diltiazem; Dose-Response Relationship, Drug; Drug Monitoring; Female; Fluconazole; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Prednisolone; Retrospective Studies; Tacrolimus

2005
Combination therapy with diltiazem plus CsA/MMF/Pred or CsA/Aza/Pred triple immunosuppressive regimens for use in clinical kidney transplantation in Northwestern China.
    European journal of clinical pharmacology, 2011, Volume: 67, Issue:6

    Topics: Adolescent; Adult; Aged; Azathioprine; Cohort Studies; Cyclosporine; Diltiazem; Drug Combinations; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Liver Function Tests; Male; Middle Aged; Mycophenolic Acid; Prednisolone; Young Adult

2011

Other Studies

24 other study(ies) available for diltiazem and prednisolone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Vasculopathy in cyclosporine-treated renal allografts: possible protection by diltiazem.
    Clinical transplantation, 1994, Volume: 8, Issue:3 Pt 1

    Topics: Adult; Arterioles; Azathioprine; Cyclosporine; Diltiazem; Female; Humans; Image Processing, Computer-Assisted; Kidney; Kidney Transplantation; Male; Prednisolone; Vascular Diseases

1994
Application of binary polymer system in drug release rate modulation. 2. Influence of formulation variables and hydrodynamic conditions on release kinetics.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:3

    Topics: Delayed-Action Preparations; Diltiazem; Kinetics; Lactose; Methylcellulose; Molecular Weight; Nifedipine; Oxazines; Pectins; Prednisolone; Pressure; Solubility; Tablets; Theophylline

1997
Diltiazem retards the metabolism of oral prednisone with effects on T-cell markers.
    Pediatric transplantation, 1999, Volume: 3, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Calcium Channel Blockers; Cytochrome P-450 Enzyme System; Diltiazem; Drug Interactions; Humans; Immunosuppressive Agents; Lymphocyte Count; Middle Aged; Prednisolone; Prednisone; T-Lymphocytes

1999
Vasospastic angina: nocturnal chest pain, eosinophilia and delayed diagnosis.
    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology, 2009, Volume: 9, Issue:6

    Topics: Acute Coronary Syndrome; Adolescent; Adrenal Cortex Hormones; Calcium Channel Blockers; Chest Pain; Coronary Angiography; Delayed Diagnosis; Diltiazem; Electrocardiography; Eosinophilia; Humans; Male; Prednisolone; Recurrence; Treatment Outcome

2009
The potential role of bone scintigraphy in the detection of deep muscular fascia involvement and calcinosis cutis in anti-synthetase syndrome.
    International journal of rheumatic diseases, 2013, Volume: 16, Issue:4

    Topics: Adult; Back Muscles; Calcinosis; Comorbidity; Cyclosporine; Diltiazem; Drug Therapy, Combination; Female; Humans; Myositis; Prednisolone; Radionuclide Imaging; Skin Diseases; Technetium; Treatment Outcome

2013
Protective effect of selected calcium channel blockers and prednisolone, a phospholipase-A2 inhibitor, against gentamicin and carbon tetrachloride-induced nephrotoxicity.
    Human & experimental toxicology, 2014, Volume: 33, Issue:8

    Topics: Animals; Antioxidants; Biomarkers; Calcium Channel Blockers; Carbon Tetrachloride; Cytoprotection; Diltiazem; Disease Models, Animal; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Nifedipine; Oxidative Stress; Phospholipase A2 Inhibitors; Prednisolone; Rats, Wistar; Time Factors; Verapamil

2014
Protective effect of carvedilol alone and coadministered with diltiazem and prednisolone on doxorubicin and 5-fluorouracil-induced hepatotoxicity and nephrotoxicity in rats.
    Pharmacology research & perspectives, 2018, Volume: 6, Issue:1

    Topics: Acute Kidney Injury; Animals; Antibiotics, Antineoplastic; Carbazoles; Carvedilol; Chemical and Drug Induced Liver Injury; Diltiazem; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Kidney; Lipid Peroxidation; Liver; Oxidative Stress; Prednisolone; Propanolamines; Protective Agents; Random Allocation; Rats; Rats, Wistar; Treatment Outcome

2018