diltiazem has been researched along with pentoxifylline in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dodson, RA; Hinds, TR; Vincenzi, FF | 1 |
| Kawakita, S; Kinoshita, M; Morita, K; Muranishi, S; Nishikawa, S; Ono, T; Shibata, N; Shimakawa, H; Takada, K | 1 |
| Morita, T; Sasaki, Y; Takeyama, S | 1 |
| Chaudry, IH; Jarrar, D; Wang, P | 1 |
| Doi, H; Inoue, H; Kaburaki, M; Narita, H; Suzumura, K | 1 |
| Bennewith, KL; Durand, RE | 1 |
2 review(s) available for diltiazem and pentoxifylline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review).
Topics: Adenosine Triphosphate; Animals; Coloring Agents; Critical Care; Cytokines; Diltiazem; Disease Models, Animal; Gene Expression Regulation; Heat-Shock Proteins; Humans; Indocyanine Green; Kupffer Cells; Lipopolysaccharides; Liver Failure; Liver Function Tests; Magnesium Chloride; Male; MAP Kinase Signaling System; Multiple Organ Failure; NF-kappa B; Nitric Oxide; Pentoxifylline; Randomized Controlled Trials as Topic; Rats; Salvage Therapy; Sepsis; Shock; Shock, Hemorrhagic; Systemic Inflammatory Response Syndrome; Wounds and Injuries | 1999 |
13 other study(ies) available for diltiazem and pentoxifylline
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Pentoxifylline, diltiazem, and A23187: effects on deformability and volume of human red blood cells.
Topics: Calcimycin; Diltiazem; Drug Interactions; Erythrocyte Deformability; Erythrocyte Volume; Humans; Pentoxifylline; Reference Values; Theobromine | 1988 |
Effects of diltiazem on rheological properties of human blood.
Topics: Adenosine Triphosphate; Blood Platelets; Blood Viscosity; Diltiazem; Erythrocyte Deformability; Erythrocytes; Humans; In Vitro Techniques; Injections, Intravenous; Middle Aged; Osmotic Fragility; Pentoxifylline | 1988 |
Effects of diltiazem on the physicochemical properties of rat erythrocyte and liposome membrane: comparison with pentoxifylline and propranolol.
Topics: Animals; Benzazepines; Blood Viscosity; Diltiazem; Erythrocyte Membrane; Erythrocytes; Fluorescent Dyes; Hemolysis; In Vitro Techniques; Liposomes; Male; Pentoxifylline; Phosphorylation; Propranolol; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Spectrin; Theobromine | 1984 |
Protective effect of TA-993, a novel therapeutic agent for peripheral circulatory insufficiency, on skeletal muscle fatigue in a rat model of hindlimb ischemia.
Topics: Animals; Blood Pressure; Blood Viscosity; Diltiazem; Heart Rate; Hindlimb; Ischemia; Muscle Fatigue; Pentoxifylline; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2000 |
Drug-induced alterations in tumour perfusion yield increases in tumour cell radiosensitivity.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Flow Cytometry; Hematologic Agents; Humans; Kinetics; Mice; Neoplasms; Pentoxifylline; Perfusion; Radiation Tolerance; Regional Blood Flow; Rubidium Radioisotopes; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2001 |