diltiazem has been researched along with pentobarbital in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Caron, G; Ermondi, G | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Pezzola, A; Popoli, P; Sagratella, S; Scotti de Carolis, A; Zeng, YC | 1 |
| Reynen, M; Yutrzenka, GJ | 1 |
| Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S | 1 |
| Kapur, PA; Sullivan, KB | 1 |
| Alatienne, M; Duchêne-Marullaz, P; Ghyselinck, N; Kantelip, JP; Talmant, JM | 1 |
| Renton, KW | 1 |
| Capuano, C; Cottrell, JE; Epstein, JM; Giffin, JP; Hartung, J; Mazzoni, P | 1 |
| Az-Ma, T; Saeki, N; Yuge, O | 1 |
| Chen, BQ; Chu, QP; Cui, XY; Ku, BS; Li, XJ; Lin, ZB; Wang, XM; Zhang, YH; Zhao, X | 1 |
| Cui, SY; Cui, XY; Sheng, ZF; Shi, XL; Wang, ZJ; Yu, B; Zhang, J; Zhang, XQ; Zhang, YH | 1 |
1 review(s) available for diltiazem and pentobarbital
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
16 other study(ies) available for diltiazem and pentobarbital
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes | 2013 |
Cromakalim (BRL 34915) counteracts the epileptiform activity elicited by diltiazem and verapamil in rats.
Topics: Animals; Anticonvulsants; Benzopyrans; Cromakalim; Diltiazem; Electric Stimulation; Electroencephalography; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; Injections, Intraventricular; Male; Pentobarbital; Pyrroles; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Verapamil | 1991 |
Diltiazem alters some withdrawal signs in pentobarbital-dependent rats.
Topics: Animals; Calcium Channels; Diltiazem; Drug Synergism; Male; Pentobarbital; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1991 |
Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs.
Topics: Analysis of Variance; Animals; Blood Pressure; Coronary Circulation; Diltiazem; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Nicardipine; Nifedipine; Pentobarbital; Sympathetic Nervous System; Tachycardia; Verapamil | 1990 |
The effect of beta-adrenergic blockade on the cardiovascular response to diltiazem or verapamil in dogs.
Topics: Animals; Catecholamines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Hemodynamics; Isoproterenol; Male; Pentobarbital; Propranolol; Receptors, Adrenergic, beta; Verapamil | 1986 |
Comparative electrophysiologic effects of bepridil, verapamil and diltiazem in conscious and anesthetized dogs.
Topics: Anesthesia, General; Animals; Atrioventricular Node; Bepridil; Calcium Channel Blockers; Diltiazem; Dogs; Female; Heart Conduction System; Hemodynamics; Male; Pentobarbital; Pyrrolidines; Sinoatrial Node; Verapamil | 1986 |
Inhibition of hepatic microsomal drug metabolism by the calcium channel blockers diltiazem and verapamil.
Topics: Aminopyrine N-Demethylase; Animals; Benzazepines; Cytochrome P-450 Enzyme System; Dealkylation; Diltiazem; In Vitro Techniques; Kinetics; Male; Mice; Microsomes, Liver; Pentobarbital; Pharmaceutical Preparations; Sleep; Verapamil | 1985 |
Intracranial pressure during diltiazem-induced hypotension in anesthetized dogs.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dogs; Heart Rate; Hypotension, Controlled; Intracranial Pressure; Nitrous Oxide; Pentobarbital; Pulmonary Wedge Pressure | 1985 |
Differential action of spasmolytic vasodilators on platelet aggregation and endothelial cell-dependent anti-aggregation.
Topics: Alprostadil; Animals; Aorta; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Nicardipine; Nitroglycerin; Nitroprusside; Papaverine; Pentobarbital; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Sympatholytics; Vasodilator Agents | 2000 |
Potentiating effects of L-type Ca(2+) channel blockers on pentobarbital-induced hypnosis are influenced by serotonergic system.
Topics: 5-Hydroxytryptophan; Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Fenclonine; Hypnotics and Sedatives; Male; Mice; Mice, Inbred ICR; Nifedipine; Pentobarbital; Serotonin; Serotonin Antagonists; Sleep; Verapamil | 2006 |
Diltiazem potentiates pentobarbital-induced hypnosis via 5-HT1A and 5-HT2A/2C receptors: role for dorsal raphe nucleus.
Topics: Animals; Brain; Calcium Channel Blockers; Cell Count; Diltiazem; Drug Synergism; Electroencephalography; Electromyography; Gene Expression; Genes, fos; Hypnotics and Sedatives; Immunohistochemistry; Male; Pentobarbital; Polysomnography; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin Antagonists; Serotonin Receptor Agonists | 2011 |