Compounds > diltiazem

Page last updated: 2024-08-23

diltiazem and oxybutynin

diltiazem has been researched along with oxybutynin in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (8.33)	18.2507
2000's	4 (33.33)	29.6817
2010's	7 (58.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M	1
Lombardo, F; Obach, RS; Waters, NJ	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chancellor, MB; Huang, B; Rivas, DA; Salzman, SK	1
Fujino Oki, T; Kato, Y; Kurosawa, S; Nanri, M; Uchida, S; Yamada, S; Yoshida, K	1
Avari, JG; Mundada, AS	1
Bhattacharjee, D; Bhattacharyya, A; Bose, M; Chattopadhyay, D; Mishra, R; Rana, D; Roy, I; Saha, NR; Sarkar, G	1

Reviews

1 review(s) available for diltiazem and oxybutynin

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

11 other study(ies) available for diltiazem and oxybutynin

Article	Year
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR. Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment. Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10 Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Autonomic dysreflexia in a rat model spinal cord injury and the effect of pharmacologic agents. Neurourology and urodynamics, 1995, Volume: 14, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Autonomic Nervous System Diseases; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Male; Mandelic Acids; Parasympatholytics; Prazosin; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Urinary Bladder, Neurogenic; Urodynamics	1995
Binding activities by propiverine and its N-oxide metabolites of L-type calcium channel antagonist receptors in the rat bladder and brain. Life sciences, 2007, Jun-06, Volume: 80, Issue:26 Topics: Analysis of Variance; Animals; Benzilates; Brain; Calcium Channels, L-Type; Diltiazem; Isradipine; Male; Mandelic Acids; N-Methylscopolamine; Protein Binding; Rats; Rats, Sprague-Dawley; Tritium; Urinary Bladder; Verapamil	2007
Novel biomaterial for transdermal application: in vitro and in vivo characterization. Drug delivery, 2011, Volume: 18, Issue:6 Topics: Acrylic Resins; Animals; Biocompatible Materials; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion Chambers, Culture; Diltiazem; Drug Carriers; Humans; Male; Permeability; Polymers; Rats; Rats, Sprague-Dawley; Resins, Plant; Skin; Skin Absorption; Solubility; Transdermal Patch	2011
Taro corms mucilage/HPMC based transdermal patch: an efficient device for delivery of diltiazem hydrochloride. International journal of biological macromolecules, 2014, Volume: 66 Topics: Administration, Cutaneous; Animals; Chemistry, Pharmaceutical; Colocasia; Diltiazem; Drug Carriers; Drug Delivery Systems; Hypromellose Derivatives; Plant Mucilage; Rats; Rats, Hairless; Skin; Solubility; Solvents; Transdermal Patch	2014