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diltiazem and oxadiazoles

diltiazem has been researched along with oxadiazoles in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199018 (56.25)18.7374
1990's11 (34.38)18.2507
2000's2 (6.25)29.6817
2010's1 (3.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glossmann, H; Knaus, HG; Staudinger, R1
Keith, RA; Moore, WC; Patel, J; Salama, AI1
Naitoh, T; Sugimoto, T; Toyo-Oka, T1
Beaufort, P; Chatelain, P; Clinet, M; Laruel, R; Meysmans, L; Nokin, P1
Harada, Y; Kimura, R; Nakayama, K; Yamada, S1
Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG1
Birnbaumer, L; Brown, AM; Kim, HS; Lacerda, AE; Rampe, D1
Glossmann, H; Goll, A; Moosburger, K; Striessnig, J1
Hosey, MM; Maan, AC; Ptasienski, J1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M; Renaud, JF; Romey, G; Schmid, A1
Becker, C; Kokubun, S; Porzig, H; Prod'hom, B; Reuter, H1
Highsmith, RF; Schwartz, A; Whitmer, KR; Williams-Lawson, JS1
Becker, C; Porzig, H1
Poder, T; Rampe, D; Schilling, WP; Zhao, ZY1
Dillon, JS; Gu, XH; Liu, JJ; Nayler, WG1
Rutledge, A; Triggle, DJ; Wei, XY1
Ferry, DR; Glossmann, H; Goll, A; Linn, T1
Cook, NS; Hof, RP1
Bevan, JA; Hwa, JJ1
Hof, RP1
Golichowski, AM; Tzeng, DY1
Dacquet, C; Mironneau, C; Mironneau, J1
Barhanin, J; Borsotto, M; Fosset, M; Galizzi, JP; Lazdunski, M1
Shinozaki, H1
Ferry, DR; Glossmann, H; Goll, A1
Dakshinamurti, K; Lal, KJ1
Brauns, T; Glossmann, H; Haugland, RP; Kimball, SD; Prinz, H; Striessnig, J1
Aida, M; Saito, W; Saito, Y; Sasaki, M; Shigenobu, K; Tanaka, H; Tanaka, Y1
Duszyk, M; Thethi, K1
Cao, LH; Choi, DH; Kang, DG; Kim, JS; Kim, SJ; Lee, H; Lee, HS; Lee, JK1
Budriesi, R; Carosati, E; Chiarini, A; Cosimelli, B; Cruciani, G; Frosini, M; Fusi, F; Ioan, P; Novellino, E; Saponara, S; Spinelli, D; Spisani, R; Ugenti, MP1
Blood, AB; Liu, T; Longo, LD; Power, GG; Schroeder, HJ; Terry, MH; Wilson, SM; Zhang, M1

Reviews

1 review(s) available for diltiazem and oxadiazoles

ArticleYear
The pharmacology of the excitatory neuromuscular junction in the crayfish.
    Progress in neurobiology, 1980, Volume: 14, Issue:2-3

    Topics: Alanine; Alkaloids; Animals; Astacoidea; Concanavalin A; Diltiazem; Evoked Potentials; gamma-Aminobutyric Acid; Glutamates; Histamine H1 Antagonists; Kainic Acid; Neuromuscular Blocking Agents; Neuromuscular Junction; Oxadiazoles; Quisqualic Acid; Ribonucleotides; Structure-Activity Relationship

1980

Other Studies

31 other study(ies) available for diltiazem and oxadiazoles

ArticleYear
Positive heterotropic allosteric regulators of dihydropyridine binding increase the Ca2+ affinity of the L-type Ca2+ channel. Stereoselective reversal by the novel Ca2+ antagonist BM 20.1140.
    The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17

    Topics: Alkaloids; Allosteric Regulation; Animals; Benzothiazoles; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Cerebral Cortex; Diltiazem; Guinea Pigs; Isomerism; Isradipine; Kinetics; Macromolecular Substances; Models, Theoretical; Muscles; Oxadiazoles; Pyridines; Pyrrolidines; Rabbits; Thiazoles; Verapamil

1991
Role of calcium in regulation of phosphoinositide signaling pathway.
    Journal of molecular neuroscience : MN, 1991, Volume: 3, Issue:1

    Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Carbachol; Cations, Divalent; Cells, Cultured; Cerebral Cortex; Diltiazem; Egtazic Acid; Inositol; Inositol Phosphates; Isradipine; Kinetics; Models, Neurological; Neurons; Oxadiazoles; Phosphatidylinositols; Quinoxalines; Quisqualic Acid; Rats; Signal Transduction; Sulfonamides; Verapamil

1991
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system.
    Biochemical and biophysical research communications, 1990, Sep-28, Volume: 171, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil

1990
SR 33557, a novel calcium entry blocker. II. Interactions with 1,4-dihydropyridine, phenylalkylamine and benzothiazepine binding sites in rat heart sarcolemmal membranes.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:2

    Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Indolizines; Isradipine; Male; Myocardium; Oxadiazoles; Phenethylamines; Radioligand Assay; Rats; Rats, Inbred Strains; Sarcolemma; Verapamil

1990
Calcium channel receptor sites for (+)-[3H]PN 200-110 in coronary artery.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Cations, Divalent; Coronary Vessels; Diltiazem; Edetic Acid; Female; In Vitro Techniques; Isradipine; Kinetics; Male; Oxadiazoles; Receptors, Nicotinic; Swine; Verapamil

1990
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
    The Journal of biological chemistry, 1990, Jul-05, Volume: 265, Issue:19

    Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil

1990
[3H]PN200-110 binding in a fibroblast cell line transformed with the alpha 1 subunit of the skeletal muscle L-type Ca2+ channel.
    Biochemical and biophysical research communications, 1990, Jun-29, Volume: 169, Issue:3

    Topics: Animals; Brain; Calcium Channels; Cell Membrane; Cloning, Molecular; Diltiazem; Gallopamil; Imines; Isradipine; L Cells; Macromolecular Substances; Mice; Muscles; Myocardium; Oxadiazoles; Receptors, Nicotinic; Sarcolemma; Transfection

1990
Purified calcium channels have three allosterically coupled drug receptors.
    FEBS letters, 1986, Mar-03, Volume: 197, Issue:1-2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil

1986
Influence of Mg++ on the effect of diltiazem to increase dihydropyridine binding to receptors on Ca++-channels in chick cardiac and skeletal muscle membranes.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Chickens; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Isradipine; Magnesium; Membranes; Muscles; Myocardium; Nitrendipine; Oxadiazoles; Receptors, Nicotinic

1986
Dihydropyridine-sensitive Ca2+ channels: molecular properties of interaction with Ca2+ channel blockers, purification, subunit structure, and differentiation.
    Journal of cardiovascular pharmacology, 1986, Volume: 8 Suppl 8

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Bepridil; Binding, Competitive; Calcium; Calcium Channel Blockers; Calcium Channels; Chick Embryo; Cholic Acids; Diltiazem; Ion Channels; Isradipine; Kinetics; Macromolecular Substances; Molecular Weight; Muscles; Myocardial Contraction; Oxadiazoles; Pyridines; Pyrrolidines; Receptors, Nicotinic; Verapamil

1986
Voltage-dependent cooperative interactions of calcium channel ligands in intact cardiac cells.
    Biomedica biochimica acta, 1987, Volume: 46, Issue:8-9

    Topics: Allosteric Site; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Ion Channels; Kinetics; Membrane Potentials; Myocardium; Nicotinic Acids; Oxadiazoles; Rats; Verapamil

1987
Effect of calcium channel modulators on isolated endothelial cells.
    Biochemical and biophysical research communications, 1988, Jul-29, Volume: 154, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzofurans; Biological Products; Bradykinin; Calcium; Carbachol; Cattle; Diltiazem; Endothelium; Fura-2; Ion Channels; Isradipine; Nitric Oxide; Oxadiazoles; Thrombin; Verapamil

1988
Potential-dependent allosteric modulation of 1,4-dihydropyridine binding by d-(cis)-diltiazem and (+/-)-verapamil in living cardiac cells.
    Molecular pharmacology, 1988, Volume: 34, Issue:2

    Topics: Allosteric Regulation; Animals; Calcium; Diltiazem; Heart; In Vitro Techniques; Ion Channels; Isradipine; Membrane Potentials; Myocardium; Oxadiazoles; Rats; Sarcolemma; Verapamil

1988
Calcium channel agonist and antagonist binding in a highly enriched sarcolemma preparation obtained from canine ventricle.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Dogs; Dose-Response Relationship, Drug; Heart Ventricles; Imines; In Vitro Techniques; Isradipine; Oxadiazoles; Sarcolemma

1989
The failure of endothelin to displace bound, radioactively-labelled, calcium antagonists (PN 200/110, D888 and diltiazem).
    British journal of pharmacology, 1989, Volume: 96, Issue:2

    Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endothelins; Female; In Vitro Techniques; Isradipine; Oxadiazoles; Peptides; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Verapamil

1989
Voltage-dependent binding of 1,4-dihydropyridine Ca2+ channel antagonists and activators in cultured neonatal rat ventricular myocytes.
    Molecular pharmacology, 1989, Volume: 35, Issue:4

    Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Diltiazem; Gallopamil; Heart Ventricles; In Vitro Techniques; Isradipine; Membrane Potentials; Oxadiazoles; Potassium; Rats

1989
Molecular approach to the calcium channel.
    Advances in myocardiology, 1985, Volume: 5

    Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil

1985
Cardioprotection by the calcium antagonist PN 200-110 in the absence and presence of cardiodepression.
    British journal of pharmacology, 1985, Volume: 86, Issue:1

    Topics: Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; In Vitro Techniques; Isradipine; Myocardial Contraction; Myocardium; Oxadiazoles; Rabbits; Time Factors; Verapamil

1985
A nimodipine-resistant Ca2+ pathway is involved in myogenic tone in a resistance artery.
    The American journal of physiology, 1986, Volume: 251, Issue:1 Pt 2

    Topics: Analysis of Variance; Animals; Arteries; Calcium; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance; Isradipine; Male; Manganese; Muscle, Smooth, Vascular; Nicotinic Acids; Nimodipine; Oxadiazoles; Potassium; Rabbits; Vascular Resistance; Verapamil

1986
Comparison of cardiodepressant and vasodilator effects of PN 200-110 (isradipine), nifedipine and diltiazem in anesthetized rabbits.
    The American journal of cardiology, 1987, Jan-30, Volume: 59, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Heart; Isradipine; Myocardial Contraction; Nifedipine; Oxadiazoles; Rabbits; Vasodilation

1987
Enhancement of binding of the dihydropyridine calcium antagonist PN200-110 to human myometrial sarcolemma by the heterologous calcium antagonist diltiazem.
    Biochemical pharmacology, 1987, Apr-01, Volume: 36, Issue:7

    Topics: Calcium Channel Blockers; Cell Fractionation; Diltiazem; Female; Humans; Isradipine; Kinetics; Myometrium; Oxadiazoles; Sarcolemma; Subcellular Fractions

1987
Effects of calcium entry blockers on calcium-dependent contractions of rat portal vein.
    British journal of pharmacology, 1987, Volume: 92, Issue:1

    Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Isradipine; Muscle Contraction; Muscle, Smooth, Vascular; Oxadiazoles; Portal Vein; Potassium; Rats; Rats, Inbred Strains

1987
Characterization and photoaffinity labeling of receptor sites for the Ca2+ channel inhibitors d-cis-diltiazem, (+/-)-bepridil, desmethoxyverapamil, and (+)-PN 200-110 in skeletal muscle transverse tubule membranes.
    The Journal of biological chemistry, 1986, Jan-25, Volume: 261, Issue:3

    Topics: Affinity Labels; Animals; Autoradiography; Benzazepines; Bepridil; Binding, Competitive; Calcium Channels; Diltiazem; Isradipine; Kinetics; Muscles; Oxadiazoles; Photochemistry; Pyrrolidines; Rabbits; Receptors, Nicotinic; Verapamil

1986
Target size analysis of skeletal muscle Ca2+ channels. Positive allosteric heterotropic regulation by d-cis-diltiazem is associated with apparent channel oligomer dissociation.
    FEBS letters, 1983, Jun-27, Volume: 157, Issue:1

    Topics: Allosteric Regulation; Animals; Benzazepines; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Male; Muscles; Oxadiazoles; Stereoisomerism

1983
Calcium channels in vitamin B6 deficiency-induced hypertension.
    Journal of hypertension, 1993, Volume: 11, Issue:12

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Diltiazem; Hypertension; Male; Nicotinic Acids; Nifedipine; Oxadiazoles; Rats; Rats, Sprague-Dawley; Verapamil; Vitamin B 6 Deficiency

1993
L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other.
    Biochemistry, 1997, Mar-25, Volume: 36, Issue:12

    Topics: Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Fluorescent Dyes; Isomerism; Isradipine; Kinetics; Nicotinic Acids; Nifedipine; Nitrendipine; Oxadiazoles; Rabbits

1997
Differential sensitivity to ATP-sensitive potassium channel openers of norepinephrine-induced contraction of guinea pig and rat aorta.
    Life sciences, 1998, Volume: 62, Issue:24

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Cromakalim; Diltiazem; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxadiazoles; Piperidines; Potassium Channels; Rats; Rats, Wistar; Vasoconstrictor Agents; Vasodilation

1998
Nitric oxide inhibits whole-cell current in cystic fibrosis pancreatic epithelial cells.
    Pancreas, 1999, Volume: 19, Issue:2

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Calcium Channel Blockers; Cell Line; Charybdotoxin; Cyclic AMP; Cyclic GMP; Cystic Fibrosis; Diltiazem; Enzyme Inhibitors; Epithelial Cells; Glutathione; Humans; Membrane Potentials; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Pancreas; Patch-Clamp Techniques; Penicillamine; Quinoxalines; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione

1999
Endothelium-dependent induction of vasorelaxation by the butanol extract of Phellinus igniarius in isolated rat aorta.
    The American journal of Chinese medicine, 2006, Volume: 34, Issue:4

    Topics: Animals; Aorta; Atropine; Butanols; Cyclic GMP; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; In Vitro Techniques; Indomethacin; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Oxadiazoles; Polyporaceae; Propranolol; Quinoxalines; Rats; Rats, Sprague-Dawley; Tetraethylammonium; Vasodilation; Vasodilator Agents; Verapamil

2006
L-Type calcium channel blockers: from diltiazem to 1,2,4-oxadiazol-5-ones via thiazinooxadiazol-3-one derivatives.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Female; Heart Rate; In Vitro Techniques; Male; Mice; Models, Molecular; Muscle Contraction; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oxadiazoles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiazines; Ventricular Function, Left; Ventricular Pressure

2009
S-nitrosothiols dilate the mesenteric artery more potently than the femoral artery by a cGMP and L-type calcium channel-dependent mechanism.
    Nitric oxide : biology and chemistry, 2016, 08-31, Volume: 58

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cyclic GMP; Cysteine; Diltiazem; Female; Femoral Artery; Fetus; Indazoles; Male; Mesenteric Arteries; Nifedipine; Oxadiazoles; Quinoxalines; S-Nitrosoglutathione; S-Nitrosothiols; Sheep; Soluble Guanylyl Cyclase; Vasodilation; Vasodilator Agents

2016