Page last updated: 2024-08-23

diltiazem and ouabain

diltiazem has been researched along with ouabain in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199015 (48.39)18.7374
1990's12 (38.71)18.2507
2000's2 (6.45)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Hoshiyama, M; Nakajima, H; Nosaka, K1
Crevat, A; Gallice, P; Kovacic, H1
Asayama, J; Inoue, D; Inoue, M; Matsumoto, T; Miyazaki, H; Nakagawa, M; Omori, I; Tatsumi, T; Yamahara, Y1
Iwasaki, T; Miyata, S; Morita, S; Nagai, K; Shibata, R1
Hilton, PJ; Poston, L; Woolfson, RG1
Kojima, M; Sperelakis, N1
Garcia, ML; Kaczorowski, GJ; King, VF; Reuben, JP; Siegl, PK1
Hunter, T; Proakis, A; Wu, KM1
Miyamae, S1
O'Rourke, RA; Walsh, RA; Watford, WH1
Hata, T; Makino, N; Nakanishi, H; Yanaga, T1
Donoso, P; Hidalgo, C; Jaimovich, E; Liberona, JL1
Braquet, P; Mest, HJ; Meyer, E; Riedel, A1
Braquet, P; Mest, HJ; Riedel, A1
Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL1
Chappell, SP; Henderson, AH; Lewis, MJ1
Weishaar, RE1
Ito, K; Morita, T; Nose, T; Sukamoto, T; Yoshidomi, M1
Canga, L; Gimeno, AL; Sterin-Broda, L1
Gross, GW; Rhoades, BK1
Britton, LW; Ferraris, VA; Kiser, LM; Sim, MF; Wallace, AM; Weishaar, RE1
Kamei, C; Sugimoto, Y1
Earm, YE; Ho, WK; So, I1
Dumont, L1
Earm, YE; Ho, WK; Leem, CH1
Cantoni, V; de Novellis, V; Fici, F; Guarino, A; Rossi, F; Stella, L; Vacca, C1
Gjini, V; Korth, M; Schmitt, C; Schömig, A; Schreieck, J; Weyerbrock, S1
Fisher, B; Gwathmey, J; Li, J; Shaw, JB; Washington, B1
Obata, T1

Other Studies

31 other study(ies) available for diltiazem and ouabain

ArticleYear
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Effects of diltiazem on the positive inotropic and vasoconstrictor responses to ouabain in vitro.
    Japanese journal of pharmacology, 1977, Volume: 27, Issue:6

    Topics: Animals; Benzazepines; Diltiazem; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Myocardial Contraction; Ouabain; Rabbits; Stimulation, Chemical; Vasoconstriction

1977
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
    Biochemical pharmacology, 1992, Oct-20, Volume: 44, Issue:8

    Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil

1992
[Effects of ouabain, caffeine, and diltiazem, on spontaneous cyclic Ca2+ release from sarcoplasmic reticulum in the skinned papillary muscles of guinea pigs].
    Kokyu to junkan. Respiration & circulation, 1991, Volume: 39, Issue:11

    Topics: Animals; Caffeine; Calcium; Diltiazem; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Ouabain; Papillary Muscles; Sarcoplasmic Reticulum

1991
Calcium dependence of ouabain-induced contraction in aortas from spontaneously hypertensive rats.
    European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2

    Topics: Animals; Aorta, Thoracic; Calcimycin; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Monensin; Muscle Contraction; Muscle, Smooth, Vascular; Ouabain; Potassium; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcolemma; Sodium

1990
Effects of ouabain and low sodium on contractility of human resistance arteries.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:6 Pt 1

    Topics: Arteries; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Humans; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Ouabain; Phentolamine; Sodium; Sodium-Potassium-Exchanging ATPase; Vascular Resistance

1990
Effects of calcium channel blockers on ouabain-induced oscillatory afterpotentials in organ-cultured young embryonic chick hearts.
    European journal of pharmacology, 1986, Mar-11, Volume: 122, Issue:1

    Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Bepridil; Calcium Channel Blockers; Chick Embryo; Diltiazem; Ion Channels; Nifedipine; Organ Culture Techniques; Ouabain; Pyrrolidines; Verapamil

1986
Binding of Ca2+ entry blockers to cardiac sarcolemmal membrane vesicles. Characterization of diltiazem-binding sites and their interaction with dihydropyridine and aralkylamine receptors.
    The Journal of biological chemistry, 1986, Jun-25, Volume: 261, Issue:18

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzazepines; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Diltiazem; Dithiothreitol; Ethylmaleimide; Female; Guinea Pigs; Hydrogen-Ion Concentration; Iodocyanopindolol; Male; Myocardium; Nifedipine; Nitrendipine; Ouabain; Pindolol; Receptors, Nicotinic; Sodium; Sodium-Potassium-Exchanging ATPase; Stereoisomerism; Temperature; Verapamil

1986
Pharmacological characterisation of a re-entry model for atrial tachycardia in conscious dogs.
    Cardiovascular research, 1989, Volume: 23, Issue:5

    Topics: Acetylcholine; Action Potentials; Adrenergic Fibers; Animals; Anti-Arrhythmia Agents; Atropine; Cardiac Pacing, Artificial; Diltiazem; Dogs; Heart Atria; Heart Conduction System; Ion Channels; Isoproterenol; Neural Conduction; Ouabain; Propranolol; Tachycardia

1989
Influence of magnesium and extracellular calcium reduction on ouabain-treated sinoatrial node cells in rabbit heart.
    Pharmacology & toxicology, 1989, Volume: 65, Issue:3

    Topics: Animals; Calcium; Diltiazem; Egtazic Acid; Heart; In Vitro Techniques; Magnesium; Myocardium; Ouabain; Rabbits; Sinoatrial Node

1989
Diltiazem attenuates the inotropic and peripheral vascular effects of cardiac glycosides.
    American heart journal, 1989, Volume: 118, Issue:4

    Topics: Animals; Aorta; Blood Pressure; Diltiazem; Dogs; Electrocardiography; Heart Rate; Hemodynamics; Myocardial Contraction; Ouabain; Vascular Resistance

1989
Modulation of Na+-Ca2+ exchange in cardiac sarcolemmal vesicles by Ca2+ antagonists.
    Molecular and cellular biochemistry, 1988, Volume: 84, Issue:1

    Topics: Adenosine Triphosphate; Alamethicin; Animals; Calcium; Calcium Channel Blockers; Digitoxigenin; Diltiazem; Dogs; Monensin; Nifedipine; Ouabain; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil

1988
Ion pathways in transverse tubules. Quantification of receptors in membranes isolated from frog and rabbit skeletal muscle.
    Biochimica et biophysica acta, 1986, Feb-13, Volume: 855, Issue:1

    Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Anura; Bungarotoxins; Calcium Channels; Carrier Proteins; Diltiazem; Ethylenediamines; Kinetics; Muscles; Nifedipine; Nitrendipine; Ouabain; Rabbits; Receptors, Cholinergic; Receptors, Drug; Receptors, Nicotinic; Sodium Channels; Sodium-Potassium-Exchanging ATPase; Temperature; Tetrodotoxin

1986
The arrhythmogenic effect of platelet activating factor (PAF) is inhibited by PAF antagonist and by substances influencing eicosanoids.
    Biomedica biochimica acta, 1988, Volume: 47, Issue:10-11

    Topics: Aconitic Acid; Animals; Arrhythmias, Cardiac; Diazepam; Diltiazem; Dogs; Guinea Pigs; Imidazoles; Myocardial Contraction; Naphthalenes; Ouabain; Platelet Activating Factor; Pyrimidines; Rats; Reference Values; Trapidil

1988
The effect of the specific PAF antagonist BN 52021 and the calcium blocker diltiazem on PAF induced arrhythmogenicity.
    Pharmacological research communications, 1987, Volume: 19, Issue:10

    Topics: Administration, Oral; Animals; Arrhythmias, Cardiac; Diltiazem; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Injections, Intravenous; Lactones; Ouabain; Platelet Activating Factor

1987
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
    Pharmacology, 1987, Volume: 34, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil

1987
Myocardial reoxygenation damage: can it be circumvented?
    Cardiovascular research, 1985, Volume: 19, Issue:5

    Topics: Animals; Calcium; Cats; Diltiazem; Heart; Hypoxia; In Vitro Techniques; Lidoflazine; Myocardial Contraction; Myocardium; Ouabain; Oxygen; Papillary Muscles; Perfusion; Rabbits; Stimulation, Chemical; Verapamil

1985
"Calcium antagonists" and "calcium agonists": is there a place in pharmacology for these two misnomers?
    Life sciences, 1984, Jul-30, Volume: 35, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Indenes; Muscle, Smooth; Muscle, Smooth, Vascular; Myocardium; Ouabain; Theophylline

1984
Antiarrhythmic effect of KB-944, a new calcium antagonist. A comparison with verapamil and diltiazem.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Benzothiazoles; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Epinephrine; Guinea Pigs; Male; Ouabain; Rats; Thiazoles; Verapamil

1982
Extracellular calcium concentration and calcium blocking agents on the action of ouabain on isolated rat atrium.
    Pharmacological research communications, 1982, Volume: 14, Issue:1

    Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Electric Stimulation; Gallopamil; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardium; Ouabain; Rats; Rats, Inbred Strains; Verapamil

1982
Potassium and calcium channel dependence of bursting in cultured neuronal networks.
    Brain research, 1994, Apr-18, Volume: 643, Issue:1-2

    Topics: 4-Aminopyridine; 8-Bromo Cyclic Adenosine Monophosphate; Acetylcholine; Animals; Apamin; Barium Compounds; Bicuculline; Calcium Channels; Cesium; Charybdotoxin; Chlorides; Choline; Diltiazem; Electrophysiology; Fetus; Magnesium Chloride; Mice; Muscarine; N-Methylaspartate; Nerve Net; Neurons; Organ Culture Techniques; Ouabain; Potassium Channels; Potassium Chloride; Scorpion Venoms; Spinal Cord; Tetraethylammonium; Tetraethylammonium Compounds; Veratridine

1994
Assessment of flosequinan's direct effect on human arterial, venous, and cardiac muscle: comparison with other classes of agents used to treat heart failure.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:5

    Topics: Captopril; Diltiazem; Heart Failure; Humans; In Vitro Techniques; Milrinone; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Ouabain; Pyridones; Quinolines; Quinolones; Vasodilator Agents

1994
The role of ions on histamine-induced depolarization in isolated guinea pig adipocytes.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:4

    Topics: Adipocytes; Animals; Calcium; Cells, Cultured; Choline; Culture Media; Diltiazem; Guinea Pigs; Histamine; Ion Channels; Male; Membrane Potentials; Mesentery; Monensin; Ouabain; Potassium; Sodium; Tetrodotoxin

1994
Effects of adriamycin on ionic currents in single cardiac myocytes of the rabbit.
    Journal of molecular and cellular cardiology, 1994, Volume: 26, Issue:2

    Topics: 4-Aminopyridine; Animals; Calcium; Diltiazem; Doxorubicin; Heart; In Vitro Techniques; Ion Transport; Membrane Potentials; Myocardium; Ouabain; Rabbits; Sarcoplasmic Reticulum; Sodium

1994
Experimental evidence that rejection, but not transplantation, modulates coronary reactivity to direct and indirect vasodilation.
    The Canadian journal of cardiology, 1994, Volume: 10, Issue:4

    Topics: Amrinone; Animals; Calcium; Coronary Circulation; Diltiazem; Dogs; Graft Rejection; Heart Transplantation; Nitroglycerin; Ouabain; Vascular Resistance; Vasodilator Agents

1994
The effect of taurine on the activation osmolality of the osmosensitive current in single ventricular myocytes of rabbits.
    Experimental physiology, 1996, Volume: 81, Issue:2

    Topics: Animals; Cells, Cultured; Chlorides; Diltiazem; Electrophysiology; Heart; Meglumine; Mesylates; Metals; Myocardium; Osmolar Concentration; Ouabain; Patch-Clamp Techniques; Rabbits; Sodium; Taurine; Tetraethylammonium; Tetraethylammonium Compounds

1996
Antiarrhythmic effects of LR-A/113 a new calcium antagonistic drug.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 93, Issue:2

    Topics: Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Calcium Chloride; Diltiazem; Male; Ouabain; Rats; Rats, Sprague-Dawley

1996
Frequency dependence in the action of the class III antiarrhythmic drug dofetilide is modulated by altering L-type calcium current and digitalis glucoside.
    Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Ion Transport; Male; Membrane Potentials; Ouabain; Phenethylamines; Sulfonamides

1998
In vivo histamine release from brain cortex: the effects of modulating cellular and extracellular sodium and calcium channels.
    European journal of pharmacology, 2000, Oct-27, Volume: 407, Issue:1-2

    Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cerebral Cortex; Diltiazem; Enzyme Inhibitors; Histamine Release; Male; Ouabain; Rats; Rats, Sprague-Dawley; Sodium Channels; Veratridine

2000
Diltiazem, a L-type calcium channel antagonist, suppresses ouabain-enhanced dopamine efflux by 1-methyl-4-phenylpyridinium ion (MPP+) in rat striatum.
    Biochimica et biophysica acta, 2006, Volume: 1760, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Diltiazem; Dopamine; Male; Ouabain; Rats; Rats, Wistar

2006