diltiazem has been researched along with nimodipine in 90 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (40.00) | 18.7374 |
1990's | 30 (33.33) | 18.2507 |
2000's | 16 (17.78) | 29.6817 |
2010's | 8 (8.89) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Janis, RA; Triggle, DJ | 1 |
Topliss, JG; Yoshida, F | 1 |
Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Montastruc, JL; Senard, JM | 1 |
Gibb, JW; Hanson, GR; Johnson, M; Mitros, K; Stone, DM; Zobrist, R | 1 |
De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
Bustamante, D; Fernandez, E; Kramer, V; Miranda, HF; Paeile, C; Pelissier, T; Pinardi, G; Saavedra, H | 1 |
Floersheim, GL | 2 |
Guido, S; Joseph, T | 1 |
Mason, RP; Moisey, DM; Shajenko, L | 1 |
Alfaro, MJ; Colado, MI; López, F; Martín, MI | 1 |
Benedetti, M; Popoli, P; Scotti de Carolis, A | 1 |
Campisi, D; Cascio Ingurgio, N; Marsala, BA; Martino, SG; Paterna, S | 1 |
Köhler, H; Marx, M; Merkel, F; Meyer zum Büschenfelde, KH; Weber, M | 1 |
Czyrak, A; Maj, J; Mogilnicka, E; Siwanowicz, J | 1 |
Capecchi, PL; Di Perri, T; Gaggelli, E; Orrico, A; Pasini, FL; Valensin, G | 1 |
Batra, S | 1 |
Carpenter, CL; Greenberg, DA; Messing, RO | 1 |
Greenberg, DA | 1 |
Carvalho, AP; Carvalho, CA; Coutinho, OP | 1 |
Andresen, MC; Kunze, DL; Torres, LA | 1 |
Angrisani, M; Berrino, L; De Paola, C; De Pasquale, M; De Santis, D; Filippelli, A; Loffreda, A; Maione, S; Matera, C; Mauro, C | 1 |
Ferry, DR; Glossmann, H; Goll, A; Linn, T | 1 |
Morón, MA; Stevens, CW; Yaksh, TL | 1 |
Barnett, DB; Walley, TJ; Woods, KL | 1 |
Ganchev, E | 1 |
Gachev, E; Karadzhaeva, G | 1 |
Bae, SJ; Herbette, LG; Kitamura, S; Sturtevant, JM | 1 |
Brush, KL; Hamilton, SL; Hawkes, MJ; Perez, M; Pratt, DR | 1 |
Bevan, JA; Hwa, JJ | 1 |
Flockerzi, V; Hofmann, F; Oeken, J; Ruth, P; von Nettelbladt, E | 1 |
Bolger, GT; Ruzycky, A; Triggle, DJ; Yousif, FB | 1 |
Bjerrum, PJ; Christensen, SB; Knudsen, JB; Linnebjerg, H; Thastrup, O | 1 |
Addonizio, P; De Paola, C; De Santis, D; Filippelli, A; Mauro, C; Molinario, L; Russo, S | 1 |
Cartheuser, CF | 1 |
Amoroso, S; Annunzia, L; Canzoniero, L; Di Renzo, G; Maida, P; Nappi, C; Taglialatela, M | 1 |
Solomon, GD | 1 |
Cooper, CL; Malik, KU; Shaffer, JE | 1 |
Kirley, TL; Schwartz, A | 1 |
Ferry, DR; Glossmann, H; Goll, A; Schober, M; Striessnig, J | 1 |
Ferry, DR; Glossmann, H | 1 |
Ferry, DR; Glossmann, H; Hofmann, F; Lübbecke, F; Mewes, R | 1 |
Ferry, DR; Glossmann, H; Goll, A | 1 |
Gould, RJ; Murphy, KM; Snyder, SH | 1 |
Peroutka, SJ | 1 |
Honn, KV; Onoda, JM; Sloane, BF | 1 |
Cooper, CL; Malik, KU | 1 |
DePover, A; Grupp, G; Grupp, IL; Schwartz, A | 1 |
Spedding, M | 1 |
Kowalski, TE; Taylor, DG | 1 |
DePover, A; DiSalvo, J; Grupp, G; Grupp, IL; Millard, RW; Schwartz, A | 1 |
Arneric, SP; Donnelly-Roberts, DL; Sullivan, JP | 1 |
Floersheim, GL; Racine, C | 1 |
Alfaro, MJ; Colado, MI; Del Val, V; Lopez, F; Martin, MI | 1 |
Boyle, SJ; Guard, S; McKnight, AT; Tang, KW; Watling, KJ; Woodruff, GN | 1 |
Goldberg, SR; Prada, J; Schindler, CW; Tella, SR | 1 |
Allain, H; Bentué-Ferrer, D; Decombe, R; Saïag, B; Van den Driessche, J | 1 |
Hongo, K; Kobayashi, S | 1 |
Nowak, G; Paul, IA; Popik, P; Skolnick, P; Young, A | 1 |
Hair, WM; Hughes, AD; Martin, G; Sever, PS; Sunman, W | 1 |
Baldy-Moulinier, M; Diochot, S; Nargeot, J; Richard, S; Valmier, J | 1 |
Fukui, M; Ikezaki, K; Matsukado, K; Nomura, T | 1 |
Löscher, W; Richter, A | 1 |
Nebe, J; Neugebauer, V; Rümenapp, P; Schaible, HG; Vanegas, H | 1 |
Hasegawa, AE; Zacny, JP | 1 |
Knot, HJ; Nelson, MT; Standen, NB | 1 |
Drew, T; Jinnah, HA; Kim, BS; Rothstein, JD; Visser, JE; Yitta, S | 1 |
McGrath, JJ; Soares, KV | 1 |
Janicak, PG; Levy, NA | 1 |
Mediratta, PK; Sharma, KK; Verma, V | 1 |
Fukazawa, Y; Kishioka, S; Maeda, T; Ozaki, M; Shimizu, N; Yamamoto, C; Yamamoto, H | 1 |
Han, X; Liu, SH; Lu, Y; Luo, CX; Sun, J; Wang, W; Yang, XM; Zhang, AX; Zhang, SG; Zhu, DY; Zhu, XJ | 1 |
Bambrick, LL; Krueger, BK; McCarthy, MM; Nuñez, JL | 1 |
Badawi, JK; Bross, S; Kamp, S; Kwon, ST; Langbein, S; Li, H | 1 |
Du, L; Shen, J; Wang, W; Wang, Z; Xing, D; Yip, S | 1 |
Bishnoi, M; Chopra, K; Kulkarni, SK | 1 |
Chang, Y; Chu, L; Chu, X; Gao, Y; Guo, H; Liu, Z; Wang, N; Zhang, J; Zhang, X; Zhang, Y; Zhao, X | 1 |
8 review(s) available for diltiazem and nimodipine
Article | Year |
---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
Calcium channel antagonists and the treatment of migraine.
Topics: Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Humans; Ion Channels; Kinetics; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1986 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Nifedipine; Nimodipine; Subarachnoid Hemorrhage | 1993 |
Diltiazem, nifedipine, nimodipine or verapamil for neuroleptic-induced tardive dyskinesia.
Topics: Antipsychotic Agents; Calcium Channel Blockers; Diltiazem; Dyskinesia, Drug-Induced; Humans; Nifedipine; Nimodipine; Verapamil | 2000 |
Calcium channel antagonists for the treatment of bipolar disorder.
Topics: Antimanic Agents; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium Compounds; Nifedipine; Nimodipine; Randomized Controlled Trials as Topic; Verapamil | 2000 |
5 trial(s) available for diltiazem and nimodipine
Article | Year |
---|---|
[Calcium channel blockers and prevention of migraine].
Topics: Adrenergic beta-Antagonists; Clinical Trials as Topic; Diltiazem; Flunarizine; Humans; Migraine Disorders; Nifedipine; Nimodipine; Verapamil | 1992 |
[Evaluation of the effects of verapamil, flunarizine, diltiazem, nimodipine and placebo in the prevention of hemicrania. A double-blind randomized cross-over study].
Topics: Adolescent; Adult; Diltiazem; Double-Blind Method; Female; Flunarizine; Humans; Male; Middle Aged; Migraine Disorders; Nimodipine; Placebos; Verapamil | 1990 |
Comparative efficacy of calcium antagonist drugs in the prophylaxis of migraine.
Topics: Calcium Channel Blockers; Cinnarizine; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Flunarizine; Humans; Migraine Disorders; Nicotinic Acids; Nifedipine; Nimodipine; Verapamil | 1985 |
The pharmacology of calcium channel antagonists: a novel class of anti-migraine agents?
Topics: Calcium Channel Blockers; Cerebrovascular Circulation; Clinical Trials as Topic; Cyproheptadine; Diltiazem; Humans; Migraine Disorders; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Nimodipine; Vasomotor System; Verapamil | 1983 |
The influence of three L-type calcium channel blockers on morphine effects in healthy volunteers.
Topics: Adjuvants, Anesthesia; Adult; Affect; Analgesics, Opioid; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Double-Blind Method; Female; Humans; Male; Morphine; Nimodipine; Pain Threshold; Psychomotor Performance; Reference Values; Verapamil | 1997 |
79 other study(ies) available for diltiazem and nimodipine
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effect of flunarizine and nimodipine on the decrease in tryptophan hydroxylase activity induced by methamphetamine and 3,4-methylenedioxymethamphetamine.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Chromatography, High Pressure Liquid; Diltiazem; Drug Interactions; Enzyme Induction; Flunarizine; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Nimodipine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Dopamine D2; Serotonin; Tryptophan Hydroxylase | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Antinociceptive effects of Ca2+ channel blockers.
Topics: Analgesics; Analysis of Variance; Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Mice; Morphine; Nifedipine; Nimodipine; Pain Measurement; Rats; Rats, Wistar; Verapamil | 1992 |
Calcium antagonists protect mice against lethal doses of ionizing radiation.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Male; Mice; Mice, Inbred C3H; Nifedipine; Nimodipine; Radiation Dosage; Radiation Injuries, Experimental; Radiation-Protective Agents | 1992 |
Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.
Topics: Animals; Blood; Calcium; Clofibrate; Dietary Fats; Diltiazem; Felodipine; Lipids; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Effect of clonidine, nimodipine and diltiazem on the in vitro opioid withdrawal response in the guinea-pig ileum.
Topics: Animals; Clonidine; Diltiazem; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Morphine Dependence; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Nimodipine; Substance Withdrawal Syndrome | 1990 |
Influence of nimodipine and diltiazem, alone and in combination, on phencyclidine-induced effects in rats: an EEG and behavioural study.
Topics: Animals; Behavior, Animal; Diltiazem; Drug Synergism; Electroencephalography; Male; Nimodipine; Phencyclidine; Rats; Rats, Inbred Strains | 1990 |
Additive effects of calcium antagonists on cyclosporin A-induced inhibition of T-cell proliferation.
Topics: Adult; Antibodies, Monoclonal; Calcium Channel Blockers; Cyclosporins; Diltiazem; Drug Synergism; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Nifedipine; Nimodipine; Phytohemagglutinins; T-Lymphocytes; Verapamil | 1990 |
Some behavioral effects of repeated administration of calcium channel antagonists.
Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Diltiazem; Exploratory Behavior; Male; Nifedipine; Nimodipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha | 1990 |
Selective 1H-NMR relaxation investigations of membrane-bound drugs in vitro. 3. Calcium-entry blockers and adenosine.
Topics: Adenosine; Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Diltiazem; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Neutrophils; Nimodipine | 1990 |
Characterization of [3H]-nitrendipine binding to uterine smooth muscle plasma membrane and its relevance to inhibition of calcium entry.
Topics: Animals; Binding, Competitive; Calcium; Cell Fractionation; Cell Membrane; Diethylstilbestrol; Diltiazem; Edetic Acid; Egtazic Acid; Female; Ion Channels; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Uterus | 1985 |
Mechanism of calcium channel inhibition by phenytoin: comparison with classical calcium channel antagonists.
Topics: Adrenal Gland Neoplasms; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Cinnarizine; Diltiazem; Flunarizine; Ion Channels; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Phenytoin; Pheochromocytoma; Potassium; Rats; Sodium; Verapamil | 1985 |
Effects of Ca2+ channel blockers on Ca2+ translocation across synaptosomal membranes.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Calcium; Calcium Channel Blockers; Diltiazem; Ion Channels; Nifedipine; Nimodipine; Sheep; Subcellular Fractions; Synaptic Membranes; Synaptosomes; Verapamil | 1986 |
Do calcium antagonists act directly on calcium channels to alter baroreceptor function?
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Ion Channels; Nifedipine; Nimodipine; Nitrendipine; Pressoreceptors; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Interference of prenatal and postnatal exposure to Ca2+-antagonist agents on rat functional development of vascular system.
Topics: Acetylcholinesterase; Animals; Animals, Newborn; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiovascular System; Catecholamines; Diltiazem; Dose-Response Relationship, Drug; Female; Gestational Age; Heart Rate; Male; N-Glycosyl Hydrolases; Nimodipine; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Vasomotor System; Verapamil | 1989 |
Molecular approach to the calcium channel.
Topics: Animals; Benzothiazoles; Binding Sites; Brain; Calcium; Cattle; Chemical Phenomena; Chemistry; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Isradipine; Muscles; Myocardium; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Oxadiazoles; Thiazoles; Verapamil | 1985 |
Diltiazem enhances and flunarizine inhibits nimodipine's antiseizure effects.
Topics: Animals; Anticonvulsants; Behavior, Animal; Diltiazem; Dose-Response Relationship, Drug; Electroencephalography; Flunarizine; Injections, Intraventricular; Male; Nimodipine; Rats; Rats, Inbred Strains; Seizures | 1989 |
Effects of calcium channel blockers on in vitro platelet function in whole blood using single platelet counting.
Topics: Adult; Calcium Channel Blockers; Collagen; Diltiazem; Epinephrine; Female; Humans; In Vitro Techniques; Male; Nifedipine; Nimodipine; Platelet Aggregation Inhibitors; Platelet Count; Verapamil | 1989 |
[The effect of the calcium antagonists nimodipin, verapamil and diltiazem on local cerebral blood flow of the cortex and thalamus in cats].
Topics: Animals; Cats; Cerebral Cortex; Diltiazem; Nimodipine; Regional Blood Flow; Thalamus; Verapamil | 1989 |
[The effect of calcium antagonists nimodipin, verapamil, diltiazem and flunarizin on local cerebral blood flow in rabbits in chronic experiments].
Topics: Animals; Cerebral Cortex; Diltiazem; Female; Flunarizine; Male; Nimodipine; Rabbits; Regional Blood Flow; Verapamil | 1989 |
The effects of calcium channel blocking drugs on the thermotropic behavior of dimyristoylphosphatidylcholine.
Topics: Calcium Channel Blockers; Calorimetry, Differential Scanning; Diltiazem; Dimyristoylphosphatidylcholine; Models, Biological; Nifedipine; Nimodipine; Nisoldipine; Thermodynamics; Verapamil | 1989 |
Low affinity binding sites for 1,4-dihydropyridines in mitochondria and in guinea pig ventricular membranes.
Topics: Animals; Calcium Channels; Cations, Divalent; Cell Membrane; Diltiazem; Guinea Pigs; Heart Ventricles; Hot Temperature; Mitochondria; Myocardium; Nimodipine; Nitrendipine; Osmolar Concentration; Protein Denaturation; Receptors, Nicotinic; Sodium Chloride; Verapamil | 1987 |
A nimodipine-resistant Ca2+ pathway is involved in myogenic tone in a resistance artery.
Topics: Analysis of Variance; Animals; Arteries; Calcium; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance; Isradipine; Male; Manganese; Muscle, Smooth, Vascular; Nicotinic Acids; Nimodipine; Oxadiazoles; Potassium; Rabbits; Vascular Resistance; Verapamil | 1986 |
Characterization of the binding sites for nimodipine and (-)-desmethoxyverapamil in bovine cardiac sarcolemma.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; Cattle; Diltiazem; Egtazic Acid; In Vitro Techniques; Kinetics; Myocardium; Nicotinic Acids; Nimodipine; Receptors, Nicotinic; Sarcolemma; Tritium; Verapamil | 1985 |
Ca2+ channel antagonist actions in bladder smooth muscle: comparative pharmacologic and [3H]nitrendipine binding studies.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Gallopamil; Guinea Pigs; In Vitro Techniques; Male; Microsomes; Muscarine; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nifedipine; Nimodipine; Nisoldipine; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic; Urinary Bladder | 1985 |
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations.
Topics: Blood Platelets; Calcimycin; Calcium; Cytoplasm; Diltiazem; Humans; Kinetics; Molecular Weight; Nimodipine; Phosphoproteins; Plant Extracts; Platelet Aggregation; Serotonin; Tetradecanoylphorbol Acetate; Thapsigargin; Thrombin; Verapamil | 1987 |
Effects of prenatal and postnatal exposure to Ca2+-antagonist agents on rat vasomotor reactivity development.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Carotid Sinus; Diltiazem; Female; Nimodipine; Norepinephrine; Pregnancy; Pressoreceptors; Rats; Verapamil | 1988 |
Slow channel inhibitor effects on brain function: tolerance to severe hypoxia in the rat.
Topics: Animals; Bencyclane; Bepridil; Brain; Calcium Channel Blockers; Cinnarizine; Diltiazem; Electroencephalography; Fendiline; Flunarizine; Gallopamil; Heart Rate; Hypoxia; Nimodipine; Prenylamine; Pyrrolidines; Rats; Rats, Inbred Strains; Respiration; Verapamil | 1988 |
Effect of different Ca2+ entry blockers on dopamine-induced inhibition of in vitro prolactin secretion.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dopamine Antagonists; Flunarizine; In Vitro Techniques; Nimodipine; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Verapamil | 1988 |
Mechanism of action of angiotensin II and bradykinin on prostaglandin synthesis and vascular tone in the isolated rat kidney. Effect of Ca++ antagonists and calmodulin inhibitors.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Bradykinin; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Dantrolene; Diltiazem; Dinoprostone; Gallic Acid; Imidazoles; Indomethacin; Kidney; Male; Nicotinic Acids; Nimodipine; Prostaglandins E; Quinacrine; Rats; Rats, Inbred Strains; Ryanodine; Stimulation, Chemical; Sulfonamides; Trifluoperazine; Vasoconstriction | 1985 |
Solubilization and affinity labeling of a dihydropyridine binding site from skeletal muscle: effects of temperature and diltiazem on [3H]dihydropyridine binding to transverse tubules.
Topics: Affinity Labels; Animals; Benzazepines; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Diltiazem; Intracellular Membranes; Kinetics; Microsomes; Microtubules; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Rabbits; Receptors, Nicotinic; Temperature | 1984 |
(-)-[3H]Desmethoxyverapamil, a novel Ca2+ channel probe. Binding characteristics and target size analysis of its receptor in skeletal muscle.
Topics: Animals; Binding Sites; Calcium; Diltiazem; Guinea Pigs; Ion Channels; Kinetics; Muscles; Nicotinic Acids; Nimodipine; Stereoisomerism; Subcellular Fractions; Verapamil | 1984 |
Evidence of multiple receptor sites within the putative calcium channel.
Topics: Animals; Brain; Calcium; Calcium Channel Blockers; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Kinetics; Membranes; Nicotinic Acids; Nimodipine; Prenylamine; Receptors, Drug; Verapamil | 1982 |
Identification of voltage operated calcium channels by binding studies: differentiation of subclasses of calcium antagonist drugs with 3H-nimodipine radioligand binding.
Topics: Animals; Brain; Calcium Channel Blockers; Cations; Cattle; Cell Membrane; Diltiazem; Guinea Pigs; In Vitro Techniques; Ion Channels; Kinetics; Male; Myocardium; Nicotinic Acids; Nimodipine; Stereoisomerism | 1983 |
Calcium channels: evidence for oligomeric nature by target size analysis.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Diltiazem; Dose-Response Relationship, Radiation; Guinea Pigs; Ion Channels; Kinetics; Muscles; Nicotinic Acids; Nimodipine | 1983 |
A simple sensitive radioreceptor assay for calcium antagonist drugs.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cattle; Cell Membrane; Cerebral Cortex; Diltiazem; In Vitro Techniques; Muscles; Nicotinic Acids; Nifedipine; Nimodipine; Nitrendipine; Prenylamine; Radioligand Assay; Receptors, Nicotinic; Verapamil | 1983 |
Antithrombogenic effects of calcium channel blockers: synergism with prostacyclin and thromboxane synthase inhibitors.
Topics: Adenosine Diphosphate; Benzofurans; Blood Platelets; Calcium Channel Blockers; Diltiazem; Drug Synergism; Epoprostenol; Humans; Nicotinic Acids; Nifedipine; Nimodipine; Oxidoreductases; Platelet Aggregation; Thrombin; Thromboxane A2; Thromboxane-A Synthase; Verapamil | 1984 |
Mechanism of action of vasopressin on prostaglandin synthesis and vascular function in the isolated rat kidney: effect of calcium antagonists and calmodulin inhibitors.
Topics: Animals; Arginine Vasopressin; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Diltiazem; Kidney; Male; Nicotinic Acids; Nimodipine; Prostaglandins; Rats; Rats, Inbred Strains; Trifluoperazine | 1984 |
Diltiazem potentiates the negative inotropic action of nimodipine in heart.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Dogs; Drug Synergism; Heart; Kinetics; Myocardial Contraction; Nicotinic Acids; Nimodipine; Rats; Sarcolemma; Stereoisomerism | 1983 |
Functional interactions of calcium-antagonists in K+-depolarized smooth muscle.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nicotinic Acids; Nimodipine; Potassium | 1983 |
Comparison of calcium channel inhibitors on vagal heart rate responses elicited by arterial baroreceptor reflexes in anesthetized dogs.
Topics: Acetylcholine; Anesthesia; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Heart Rate; In Vitro Techniques; Male; Nicotinic Acids; Nifedipine; Nimodipine; Nitroprusside; Norepinephrine; Pressoreceptors; Reflex; Vagus Nerve; Verapamil | 1984 |
Chronotropic, inotropic, and vasodilator actions of diltiazem, nifedipine, and verapamil. A comparative study of physiological responses and membrane receptor activity.
Topics: Animals; Benzazepines; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Diltiazem; Dogs; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardial Contraction; Nicotinic Acids; Nifedipine; Nimodipine; Potassium; Pyridines; Receptors, Drug; Vasodilation; Verapamil | 1983 |
Functional modulation of human "ganglionic-like" neuronal nicotinic acetylcholine receptors (nAChRs) by L-type calcium channel antagonists.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Cadmium; Calcium Channel Blockers; Calcium Channels; Diltiazem; Humans; Isradipine; Neuroblastoma; Neurons; Nicotine; Nifedipine; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Peptides; Receptors, Nicotinic; Spider Venoms; Tumor Cells, Cultured; Verapamil | 1995 |
Calcium antagonist radioprotectors do not reduce radiotherapeutic efficacy in three human tumor xenografts.
Topics: Adenocarcinoma; Animals; Calcium Channel Blockers; Colonic Neoplasms; Diltiazem; Humans; Male; Mice; Mice, Inbred C3H; Mice, Nude; Neoplasm Transplantation; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Radiotherapy Dosage; Sarcoma, Ewing; Transplantation, Heterologous; Whole-Body Irradiation | 1995 |
Effect of nimodipine, diltiazem and BAY K 8644 on the behavioural and neurochemical changes associated with naloxone-precipitated withdrawal in the rat. A comparison with clonidine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Behavior, Animal; Brain Chemistry; Clonidine; Diltiazem; Hydroxyindoleacetic Acid; Male; Morphine Dependence; Naloxone; Nimodipine; Rats; Rats, Sprague-Dawley; Serotonin; Spinal Cord; Substance Withdrawal Syndrome | 1993 |
The interaction of the NK1 receptor antagonist CP-96,345 with L-type calcium channels and its functional consequences.
Topics: Animals; Biphenyl Compounds; Calcium Channels; Cerebral Cortex; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Membranes; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Neurokinin-1 Receptor Antagonists; Nimodipine; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stereoisomerism; Substance P; Succinimides; Trachea | 1993 |
Calcium channel blockers antagonize some of cocaine's cardiovascular effects, but fail to alter cocaine's behavioral effects.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Diltiazem; Heart Rate; Male; Nimodipine; Saimiri; Self Administration; Verapamil | 1995 |
L-type voltage-dependent calcium channels do not modulate aminergic neurotransmitter release induced by transient global cerebral ischaemia: an in vivo microdialysis study in rat.
Topics: Animals; Biogenic Monoamines; Biological Availability; Calcium Channels; Corpus Striatum; Dialysis; Diltiazem; Injections; Ischemic Attack, Transient; Male; Neurotransmitter Agents; Nimodipine; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Ca2+ antagonists effect an antidepressant-like adaptation of the NMDA receptor complex.
Topics: Animals; Antidepressive Agents; Binding Sites; Calcium Channel Blockers; Cerebral Cortex; Depression; Diltiazem; Glycine; Kynurenic Acid; Male; Mice; Nimodipine; Receptors, N-Methyl-D-Aspartate | 1993 |
Effect of calcium antagonists on endothelin-induced contraction of isolated human resistance arteries: differences related to site of origin.
Topics: Adipose Tissue; Adult; Aged; Arteries; Calcium Channel Blockers; Calcium Channels; Diltiazem; Endothelins; Flunarizine; Humans; Membrane Potentials; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Myography; Nimodipine; Nisoldipine; Omentum; Vasoconstriction; Verapamil | 1993 |
Radioprotective effects of calcium antagonists used alone or with other types of radioprotectors.
Topics: Animals; Aspartic Acid; Calcium Channel Blockers; Diltiazem; Dimethyl Sulfoxide; Drug Combinations; Female; Flunarizine; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Radiation-Protective Agents; Verapamil; Zinc | 1993 |
Dihydropyridines, phenylalkylamines and benzothiazepines block N-, P/Q- and R-type calcium currents.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Ganglia, Spinal; Heart; Homovanillic Acid; In Vitro Techniques; Ion Channel Gating; Mice; Motor Neurons; Myocardium; Neurons, Afferent; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Spider Venoms; Verapamil | 1995 |
Effect of calcium antagonists on regional cerebral blood flow in transplanted rat brain tumors.
Topics: Analysis of Variance; Animals; Brain; Brain Neoplasms; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Flunarizine; Glioma; Male; Neoplasm Transplantation; Nifedipine; Nimodipine; Rats; Rats, Wistar; Verapamil | 1996 |
Antidystonic effects of L-type Ca2+ channel antagonists in a hamster model of idiopathic dystonia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Cricetinae; Diltiazem; Dystonia; Female; Male; Nimodipine | 1996 |
Effects of N- and L-type calcium channel antagonists on the responses of nociceptive spinal cord neurons to mechanical stimulation of the normal and the inflamed knee joint.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Diltiazem; Drug Evaluation, Preclinical; Inflammation; Knee Joint; Male; Neurons; Nimodipine; Nociceptors; omega-Conotoxin GVIA; Peptides; Rats; Rats, Wistar; Reference Values; Spinal Cord; Stress, Mechanical | 1996 |
Ryanodine receptors regulate arterial diameter and wall [Ca2+] in cerebral arteries of rat via Ca2+-dependent K+ channels.
Topics: Animals; Caffeine; Calcium Channel Blockers; Cerebral Arteries; Diltiazem; Endothelium, Vascular; Female; In Vitro Techniques; Kinetics; Membrane Potentials; Microscopy, Video; Models, Cardiovascular; Muscle, Smooth, Vascular; Nimodipine; Peptides; Potassium Channels; Potassium Channels, Tandem Pore Domain; Rats; Rats, Sprague-Dawley; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Time Factors; Vasoconstriction | 1998 |
Calcium channel activation and self-biting in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aggression; Animals; Behavior, Animal; Bites and Stings; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diltiazem; Ion Channel Gating; Mice; Mice, Inbred C57BL; Nifedipine; Nimodipine; Nitrendipine; Pyrroles; Self-Injurious Behavior | 1999 |
Potentiation of analgesia and reversal of tolerance to morphine by calcium channel blockers.
Topics: Analgesia; Animals; Calcium Channel Blockers; Diltiazem; Drug Interactions; Drug Tolerance; Female; Flunarizine; Male; Mice; Morphine; Nimodipine; Pain Threshold; Verapamil | 2001 |
Role of pharmacokinetic effects in the potentiation of morphine analgesia by L-type calcium channel blockers in mice.
Topics: Analgesia; Animals; Area Under Curve; Brain; Brain Chemistry; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Morphine; Nimodipine; Pain; Pain Measurement; Physical Stimulation; Tissue Distribution; Verapamil | 2004 |
Blockade of L-type voltage-gated Ca channel inhibits ischemia-induced neurogenesis by down-regulating iNOS expression in adult mouse.
Topics: Animals; Arterial Occlusive Diseases; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Dentate Gyrus; Diltiazem; Down-Regulation; Male; Mice; Mice, Inbred C57BL; Middle Cerebral Artery; Nerve Regeneration; Nimodipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type II | 2005 |
Prolongation and enhancement of gamma-aminobutyric acid receptor mediated excitation by chronic treatment with estradiol in developing rat hippocampal neurons.
Topics: Animals; Bicuculline; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diagnostic Imaging; Diltiazem; Dizocilpine Maleate; Drug Administration Schedule; Drug Interactions; Embryo, Mammalian; Estradiol; Excitatory Amino Acid Antagonists; Female; Fura-2; GABA Agonists; GABA Antagonists; Glutamic Acid; Hippocampus; K Cl- Cotransporters; Muscimol; Neurons; Nimodipine; Potassium Chloride; Pregnancy; Quinoxalines; Rats; Receptors, GABA-A; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2; Symporters; Time Factors | 2005 |
Inhibitory effects of L- and T-type calcium antagonists on contractions of human detrusor muscle.
Topics: Adult; Aged; Analysis of Variance; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Carbachol; Diltiazem; Female; Humans; In Vitro Techniques; Male; Mibefradil; Middle Aged; Muscle Contraction; Muscle, Smooth; Nifedipine; Nimodipine; Potassium; Urinary Bladder; Verapamil | 2006 |
Brazilein-induced contraction of rat arterial smooth muscle involves activation of Ca2+ entry and ROK, ERK pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Aorta, Thoracic; Benzopyrans; Caesalpinia; Caffeine; Calcium; Diltiazem; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Indenes; Male; Molecular Structure; Muscle Contraction; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nimodipine; Nitric Oxide Synthase; Phenylephrine; Pinacidil; Potassium Chloride; Rats; Rats, Wistar; rho-Associated Kinases; Signal Transduction; Vasoconstriction | 2008 |
Protective effect of L-type calcium channel blockers against haloperidol-induced orofacial dyskinesia: a behavioural, biochemical and neurochemical study.
Topics: Animals; Antioxidants; Antipsychotic Agents; Behavior, Animal; Calcium Channel Blockers; Calcium Channels, L-Type; Corpus Striatum; Diltiazem; Dopamine; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Movement Disorders; Nifedipine; Nimodipine; Random Allocation; Rats; Rats, Wistar; Serotonin; Verapamil | 2008 |
Calcium channel blockers ameliorate iron overload-associated hepatic fibrosis by altering iron transport and stellate cell apoptosis.
Topics: Animals; Apoptosis; Calcium Channel Blockers; Cell Line; Collagen; Deferoxamine; Diltiazem; Hepatic Stellate Cells; Iron; Iron Overload; Liver; Liver Cirrhosis; Male; Matrix Metalloproteinase 13; Mice; Nimodipine; Rats; Tissue Inhibitor of Metalloproteinase-1; Verapamil | 2016 |