diltiazem has been researched along with nicardipine in 192 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 57 (29.69) | 18.7374 |
| 1990's | 88 (45.83) | 18.2507 |
| 2000's | 32 (16.67) | 29.6817 |
| 2010's | 15 (7.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujita, M; Iso, T; Iwao, J; Kato, E; Kawashima, Y; Oya, M; Tabashi, K; Yamamoto, K | 1 |
| Janis, RA; Triggle, DJ | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Globisch, C; Kassack, MU; Klinkhammer, W; Müller, H; Pajeva, IK; Wiese, M | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Müller, H; Pick, A; Wiese, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Chen, CY; Kuo, SY; Yang, YH | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B | 1 |
| Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kobayashi, M; Niwa, M; Nozaki, M; Tsurumi, K | 1 |
| Crevat, A; Gallice, P; Kovacic, H | 1 |
| Akaike, N; Kameda, H; Kataoka, M; Takahashi, K; Ueno, S | 1 |
| Baeyens, JM; Carlos, R; Del Pozo, E; Ocaña, M | 1 |
| Fukuzaki, M; Gotoh, S; Gotoh, Y; Makita, T; Morooka, H; Shibata, O | 1 |
| Boehme, P; Mak, IT; Weglicki, WB | 1 |
| Gürdal, H; Sara, Y; Tulunay, FC | 1 |
| Mustafa, AA | 1 |
| Panarace, G; Pedrinelli, R; Salvetti, A | 1 |
| Cocchi, R; Esposti, ED; Fabbri, A; Fusaroli, M; Guerrini, L; Mandreoli, M | 1 |
| Kimura, T; Mukaiyama, O; Satoh, E; Satoh, S | 1 |
| Baeyens, JM; Barrios, M | 1 |
| Gaginella, TS; Gullikson, GW; Moummi, C | 1 |
| Shimizu, M; Yamawaki, S | 1 |
| Aupetit, JF; Faucon, G; Gerentes-Chassagne, I; Kioueh, I; Larbre, JP; Loufoua-Moundanga, J; Timour, Q | 1 |
| Aoki, K; Kishimoto, T; Naruchi, T; Okamiya, Y; Takeshita, T; Tanabe, H | 1 |
| Fujiwara, Y; Fukunaga, M; Kamada, T; Ochi, S; Orita, Y; Takama, T; Yokoyama, K | 1 |
| Akita, S; Fujii, K; Kawahara, M; Morio, M | 1 |
| Masumoto, N; Miyake, A; Tanizawa, O; Tasaka, K | 1 |
| Furuta, T; Iso, T; Miyawaki, N; Shigei, T; Yamauchi, H | 1 |
| Imanaka-Yoshida, K; Katayama, Y; Kusagawa, M; Murata, T; Onoda, K; Takao, M; Yada, I | 1 |
| Pedrinelli, R; Salvetti, A | 1 |
| Furui, H; Furumichi, T; Saito, H; Yamada, Y; Yamauchi, K; Yokota, M | 1 |
| Iso, T; Miyawaki, N; Nishimura, K; Yamauchi, H | 1 |
| Furui, H; Furumichi, T; Hayashi, H; Saito, H; Suzuki, T; Yamada, Y; Yamauchi, K; Yokota, M | 1 |
| Cristol, JP; Jover, B; Mimran, A; Ribstein, J; Valentin, JP | 1 |
| Akaike, N; Kanaide, H; Kuga, T; Nakamura, M; Sadoshima, J; Tomoike, H | 1 |
| Akaike, N; Takahashi, K | 1 |
| Akatsuka, N; Hara, K; Kurokawa, K; Ochiai, M; Ohno, M; Taguchi, J | 1 |
| Bidzinski, A; Jankowska, E; Pucilowski, O | 1 |
| Alle, M; Cieslinski, G; Kaltenbach, M; Kober, G; Noack, H; Reifart, N; Roebruck, P; Schneider, W | 1 |
| Feuerstein, G; Gleason, MM; Lysko, PG; Yue, TL | 1 |
| Doi, S; Hagiwara, A; Izumo, A; Kato, M; Tanabe, K | 1 |
| Abe, T; Fujii, Y; Fujioka, S; Ina, H; Maseki, T; Yoshida, K | 1 |
| Borgers, M; De Clerck, F; Vandewiele, R; Ver Donck, L; Verellen, G | 1 |
| Halimi, JM; Mimran, A; Ribstein, J; Valentin, JP | 1 |
| Kato, H; Takata, Y | 4 |
| Kitamura, K; Kuriyama, H; Terada, K | 1 |
| Ohshika, H; Takemura, H | 1 |
| Furuta, T | 1 |
| Chang, CC; Chiou, LC; Hong, SJ; Huang, CY; Hwang, LL | 1 |
| Azzollini, F; Cereda, A; Pelosi, G; Picca, M | 1 |
| Asai, K; Funaki, C; Hayashi, T; Kuzuya, F; Kuzuya, M; Naito, M | 1 |
| Dacquet, C; Loirand, G; Mironneau, C; Mironneau, J; Pacaud, P; Rakotoarisoa, L; Sayet, I | 1 |
| Argentino, L; Barattolo, R; Colucci, S; Grano, M; Hruska, KA; Miyauchi, A; Teitelbaum, SL; Teti, A; Zambonin Zallone, A | 1 |
| Omae, T | 1 |
| Piepho, RW; Sowers, JR | 1 |
| Honn, KV; Nelson, KK; Onoda, JM; Taylor, JD | 1 |
| Burgess, AM; Vere, DW | 1 |
| Ogihara, M | 1 |
| Back, DJ; Breckenridge, AM; Tjia, JF | 1 |
| Suga, T; Watanabe, T | 1 |
| Aleixandre, MA; Ayala, LE; García Mora, L | 1 |
| Green, J; Kleeman, CR; Muallem, S; Yamaguchi, DT | 1 |
| Frais, MA; Jackson, N; Midtbo, KA; Reynolds, G; Sharma, S; Silke, B; Taylor, SH; Verma, SP | 1 |
| Jayakody, RL; Kappagoda, T; Senaratne, MP | 1 |
| Barbieri, L; Camerini, F; Mestroni, L | 1 |
| Khurmi, NS; Raftery, EB | 1 |
| Bolognesi, R; Cimicchi, MC; Gnudi, A; Manca, C; Orlandi, N; Perrone, A; Pezzarossa, A | 1 |
| Feldman, RL; Hill, JA; Lambert, CR; Prida, XE | 1 |
| Karasawa, A; Kubo, K; Nakamizo, N; Oka, T | 1 |
| Bernard, JM; Pinaud, M | 1 |
| Hirakawa, S; Ito, H; Kotoo, Y; Sahashi, T; Takai, K; Wada, H | 1 |
| Baeyens, JM; Carlos, R; del Pozo, E; Salvador, A | 1 |
| Endou, K; Sato, T; Yamamoto, H | 1 |
| Freslon, JL; Julou-Schaeffer, G | 1 |
| Sampi, K | 1 |
| Jayakody, RL; Kappagoda, CT; Senaratne, MP; Sreeharan, N | 1 |
| Fujita, T; Hirata, Y; Takata, S; Tomita, M | 1 |
| Dang Tran, L; Gaillard, G; Montastruc, JL; Montastruc, P; Valet, P | 1 |
| Abe, K; Imai, Y; Minami, N; Sasaki, S; Seino, M; Taira, N; Yoshinaga, K | 1 |
| Jayakody, RL; Kappagoda, CT; Senaratne, MP | 1 |
| Kondo, M; Miyamura, K; Moriyama, Y; Nanjo, K; Nishi, M; Sanke, T | 1 |
| Frances, H; Renwart, N; Simon, P | 1 |
| Henry, PD | 1 |
| Borgers, M; Donck, LV; Pauwels, PJ; Vandeplassche, G | 1 |
| Fujii, K; Inoue, R; Yamanaka, K; Yoshitomi, T | 1 |
| Hagiwara, Y; Hara, T; Hirashima, T; Kokumi, N; Oomiya, A | 1 |
| Bristow, MR; Ginsburg, R; Laser, JA; McAuley, BJ; Minobe, W | 1 |
| Abrile, PG; Boero, E; Castrignano, A; Livi, A; Maffei, P; Magaia, O; Mocini, A; Perugini, P; Seu, V | 1 |
| Kashimoto, T; Ohtsubo, N; Shimizu, C; Tachikawa, E; Takahashi, E; Takahashi, S | 1 |
| McClelland, DL; Rosenkranz, RP; Roszkowski, AP | 1 |
| Asai, K; Kuzuya, F; Naito, M; Shibata, K; Yoshimine, N | 1 |
| Arimitsu, T; Mori, K; Oda, Y; Okumura, T | 1 |
| Advenier, C; Cerrina, J; Duroux, P; Floch, A; Renier, A | 1 |
| Becker, HJ; Dowinsky, S; Hopf, R; Kaltenbach, M; Kober, G | 1 |
| Hof, RP | 1 |
| Bala Subramanian, V | 1 |
| Fujii, Y; Saitoh, Y; Tanaka, H; Toyooka, H | 1 |
| Hagihara, T; Kishi, Y; Matsumoto, G; Matsuo, H; Naka, K; Nanjo, K; Ohoshi, T; Sanke, T; Sasaki, H; Sowa, R | 1 |
| Chauvet-Monges, AM; Crevat, A; Salducci, MD; Tabouy, L | 1 |
| Dohi, Y; Kojima, M; Sato, K | 1 |
| Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K | 1 |
| Casiglia, E; Dorigatti, F; Graniero, GR; Lotoro, F; Palatini, P; Pessina, AC; Vriz, O | 1 |
| Bretnall, AE; Clarke, GS | 1 |
| Hibi, M; Iwase, J; Kawamura, M; Murakami, F; Usui, A; Yoshida, K | 1 |
| Mak, IT; Weglicki, WB | 1 |
| Hirayama, T; Kano, T; Katayama, Y; Tsubokawa, T | 1 |
| Shigenobu, K; Takagi, N; Tanaka, H | 1 |
| Hiraki, S; Hirata, H; Kaji, Y | 1 |
| Gotou, M; Hosoda, Y; Kikuchi, N; Kudou, H; Minami, S; Nukariya, M; Satoh, T; Tahara, M; Takazawa, K; Watanabe, M | 1 |
| Adachi-Akahane, S; Higashidate, S; Imai, K; Nagao, T; Prados, PR; Santa, T | 1 |
| Allain, H; Bentue-Ferrer, D; Milon, D; Rault, B; Saïag, B; Van den Driessche, J | 1 |
| Hongo, K; Kobayashi, S | 1 |
| Cousins, HM; Edwards, FR; Hirst, GD; Wendt, IR | 1 |
| Nishizawa, Y | 1 |
| Sanada, H | 1 |
| Atarashi, K; Furuya, Y; Kobayashi, N; Ohe, Y; Satoh, K; Tachibana, C | 1 |
| Bali, JP; Bobo, MH; Christen, MO; Magous, R | 1 |
| Iwasaki, H; Kawamata, M; Namiki, A; Omote, K; Sonoda, H | 1 |
| Fukusaki, M; Goto, Y; Ogata, K; Tomiyasu, S; Tsujita, T | 1 |
| Pedrinelli, R; Spessot, M | 1 |
| Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H | 1 |
| Arnaoudov, PI; Latour, C; Nahas, GG; Trouvé, R | 1 |
| Balakumaran, A; Campbell, GA; Moslen, MT | 1 |
| Honda, N; Miyagawa, A; Mizutani, A; Oyama, T; Taniguchi, K | 1 |
| Kawasaki, T; Nagasawa, M; Yoshimi, T | 1 |
| Chen, D; Harakal, C; Kim, DC; Mitra, A; Perrotta, VJ; Shuman, CA; Wendling, WW | 1 |
| Maekawa, N; Mikawa, K; Nishina, K; Obara, H | 1 |
| Overstreet, DH; Pucilowski, O; Rezvani, AH | 1 |
| Görgün, CZ; Güney, HZ; Güzey, C; Hodoğluğil, U; Savran, B; Zengil, H | 1 |
| Attolini, L; Bruguerolle, B; Gantenbein, M; Grignon, S; Jacob, D | 1 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Del Castillo, B; Doi, H; Homma, H; Imai, K; Martin, MA; Narita, H; Prados, P; Santa, T | 1 |
| Shimada, H; Sugino, H | 1 |
| White, CM | 1 |
| Frielingsdorf, J; Hess, OM; Hug, R; Kaufmann, PA; Mandinov, L; Seiler, C | 1 |
| Nakayama, K; Tanaka, Y | 1 |
| Fujimura, A; Harada, K; Ohmori, M; Sugimoto, K | 1 |
| Kotegawa, T; Nakamura, K; Nakano, S; Nakatsuka, K; Tsutsumi, K; Yatsuka, YI | 1 |
| Fujii, Y; Kihara, S; Takahashi, S; Tanaka, H; Toyooka, H | 1 |
| Seibold, JR; Sturgill, MG | 1 |
| Doğrul, A; Yeşilyurt, O | 1 |
| Gao, X; Gillman, MW; Goldman, L; Hertzmark, E; McLaughlin, TJ; Ross-Degnan, D; Soumerai, SB; Spiegelman, D | 1 |
| Kajiwara, H; Kameda, H; Takasaki, A; Takeo, S; Tanonaka, K | 1 |
| Hoshino, T; Kikkawa, K; Murata, S; Yamauchi-Kohno, R | 1 |
| Nagao, T; Nishida, M; Sakamoto, K; Urushidani, T | 1 |
| Ito, M; Kimura, T; Komatsu, T; Nishiwaki, K; Shimada, Y | 1 |
| He, GW; Yang, CQ | 1 |
| Ishii, K; Nakayama, K; Tanaka, Y; Uchida, H | 1 |
| Donovan, DJ; Fugit, MD; Rubal, BJ | 1 |
| Az-Ma, T; Saeki, N; Yuge, O | 1 |
| Gando, S; Kemmotsu, O; Morimoto, Y; Shibano, T; Shikama, H | 1 |
| Fujimori, Y; Kamisaki, Y; Maeda, S; Morisaki, I; Saeki, M | 1 |
| Bali, JP; Balmes, JL; Boyer, JC; Christen, MO; Magous, R | 1 |
| Canver, CC; Chanda, J | 1 |
| Akimoto, Y; Fujii, A; Matsumoto, H; Noji, I | 1 |
| Tsutsui, T | 1 |
| Aikawa, T; Fujisaki, R; Hirayama, W; Ishii, T; Kawanishi, T; Miyamoto, Y; Shigenobu, K; Tanaka, H; Tanaka, Y | 1 |
| Arakawa, N; Hiramori, K; Nagano, M; Naganuma, Y; Nakamura, M; Yoshida, H | 1 |
| Townes-Anderson, E; Zhang, N | 1 |
| Adachi-Akahane, S; Hagiwara, M; Nagao, T | 1 |
| Hashiba, E; Hirota, K; Kabara, S; Matsuki, A; Yoshioka, H | 1 |
| Fujii, Y | 1 |
| Pope, J | 1 |
| Hirota, K; Ishihara, H; Kabara, S; Kitayama, M; Kushikata, T; Matsuki, A | 1 |
| Dezawa, M; Ishikawa, F; Ishikawa, H; Mamiya, K; Metoki, T; Nakazawa, M; Ohguro, H; Ohguro, I; Takano, Y; Yamazaki, H | 1 |
| Allen, K; Kunze, KL; Lin, YS; McConn, DJ; Thummel, KE | 1 |
| Erol, K; Gulbas, Z; Ozdener, F; Sirmagül, B | 1 |
| Bernal, JM; Cubeddu, RJ; Don, CW; Kiernan, GD; Kiernan, TJ; Ruggiero, NJ; Witzke, C; Yan, BP | 1 |
| Hara, T; Harioka, T; Ishiyama, T; Kimura, Y; Matsukawa, T; Nakasato, A; Okamura, M | 1 |
| Kurita, H; Nakajima, H; Ogura, T; Ooigawa, H; Takeda, R | 1 |
| Jeong, JH; Kang, C; Kang, TS; Kim, DH; Kim, RB; Kim, SC; Lee, DH; Lee, SH; Shin, IW | 1 |
| Imai, H; Inano, A; Kataoka, M; Morimoto, T; Mutaguchi, K; Ohashi, K; Sugiyama, Y; Suzaki, Y; Togashi, K; Yamashita, S | 1 |
| Alnajjar, LM; Bulatova, NR; Darwish, RM | 1 |
10 review(s) available for diltiazem and nicardipine
| Article | Year |
|---|---|
New developments in Ca2+ channel antagonists.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Calmodulin; Electrophysiology; Heart; Humans; Ion Channels; Muscle Relaxation; Muscle, Smooth; Potassium; Sodium; Structure-Activity Relationship; Substrate Specificity | 1983 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
[Calcium antagonists in congestive heart failure].
Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil | 1988 |
Atherosclerosis, calcium, and calcium antagonists.
Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcinosis; Calcium; Calcium Channel Blockers; Cell Survival; Cholesterol, Dietary; Cinnarizine; Diltiazem; Flunarizine; Humans; Membrane Lipids; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Propranolol; Rabbits; Verapamil | 1985 |
[Treatment of angina pectoris with calcium antagonists].
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Diltiazem; Drug Therapy, Combination; Exercise Test; Fendiline; Humans; Nicardipine; Nifedipine; Perhexiline; Prenylamine; Propafenone; Propiophenones; Verapamil | 1982 |
Calcium antagonists for the treatment of vasospasm following subarachnoid haemorrhage.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Nifedipine; Nimodipine; Subarachnoid Hemorrhage | 1993 |
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil | 1997 |
Raynaud's phenomenon (primary).
Topics: Amlodipine; Diltiazem; Humans; Nafronyl; Nicardipine; Nifedipine; Raynaud Disease; Vasodilator Agents | 2003 |
The no-reflow phenomenon in the coronary circulation.
Topics: Adenosine; Animals; Coronary Circulation; Diltiazem; Humans; Nicardipine; Nicorandil; Nitroprusside; No-Reflow Phenomenon; Prostheses and Implants; Vasodilator Agents; Verapamil | 2009 |
22 trial(s) available for diltiazem and nicardipine
| Article | Year |
|---|---|
Calcium entry blockade and adrenergic vascular reactivity in hypertensives: differences between nicardipine and diltiazem.
Topics: Adrenergic alpha-Antagonists; Adult; Biological Transport; Blood Vessels; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Nicardipine; Norepinephrine; Propranolol; Vasoconstriction; Vasodilation | 1991 |
Retardation of development and progression of coronary atherosclerosis: a new indication for calcium antagonists?
Topics: Animals; Coronary Artery Bypass; Coronary Artery Disease; Diet, Atherogenic; Diltiazem; Female; Humans; Male; Nicardipine; Prospective Studies; Rabbits; Retrospective Studies; Time Factors; Verapamil | 1990 |
Comparison of the antianginal efficacy of four calcium antagonists and propranolol in stable angina pectoris.
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Exercise Test; Female; Humans; Male; Nicardipine; Nifedipine; Nitroglycerin; Propranolol; Single-Blind Method; Verapamil | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Middle Aged; Multicenter Studies as Topic; Nicardipine; Nifedipine; Random Allocation | 1989 |
Comparative hemodynamic dose-response effects of five slow calcium channel-blocking agents in coronary artery disease.
Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Prospective Studies; Random Allocation; Verapamil | 1987 |
Comparative effects of prolonged therapy with four calcium ion antagonists (diltiazem, nicardipine, tiapamil and verapamil) in patients with chronic stable angina pectoris.
Topics: Adult; Aged; Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Diltiazem; Female; Humans; Male; Middle Aged; Nicardipine; Propylamines; Tiapamil Hydrochloride; Verapamil | 1987 |
[Preliminary note on the use of calcium antagonists in ischemic cardiopathy].
Topics: Adult; Angina Pectoris; Benzazepines; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Female; Humans; Male; Middle Aged; Myocardial Infarction; Nicardipine; Nifedipine | 1984 |
Effects of calcium channel blockers on circulatory response to tracheal intubation in hypertensive patients: nicardipine versus diltiazem.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Nicardipine | 1995 |
Diltiazem vs. nicardipine on ambulatory and exercise blood pressure and on peripheral hemodynamics.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Preparations; Diltiazem; Exercise; Exercise Test; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Plethysmography; Vascular Resistance | 1995 |
[Effect of nicardipine cardioplegia on A-V conduction system in coronary bypass surgery].
Topics: Angina Pectoris; Coronary Artery Bypass; Diltiazem; Heart Conduction System; Humans; Middle Aged; Nicardipine; Potassium Compounds | 1994 |
The effect of calcium channel antagonist administered by iontophoresis on the pain threshold.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Drug Combinations; Female; Humans; Iontophoresis; Lidocaine; Male; Nicardipine; Pain; Sensory Thresholds; Time Factors; Verapamil | 1995 |
Comparison of nicardipine, diltiazem and verapamil for controlling the cardiovascular responses to tracheal intubation.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Epinephrine; Female; Heart Rate; Hemodynamics; Humans; Intubation, Intratracheal; Laryngoscopy; Male; Middle Aged; Nicardipine; Norepinephrine; Preanesthetic Medication; Verapamil | 1996 |
Comparison of venodilatory effect of nicardipine, diltiazem, and verapamil in human subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Hand; Heart Rate; Humans; Male; Nicardipine; Vasodilator Agents; Veins; Verapamil | 1998 |
Interaction between timolol eyedrops and oral nicardipine or oral diltiazem in healthy Japanese subjects.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Asian People; Blood Pressure; Diltiazem; Double-Blind Method; Exercise Test; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Japan; Male; Nicardipine; Ophthalmic Solutions; Reference Values; Timolol; Vasodilator Agents | 1998 |
Calcium channel blockers attenuate cardiovascular responses to tracheal extubation in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Nicardipine; Orthopedic Procedures | 1998 |
Heart rate and blood pressure power spectral analysis during calcium channel blocker induced hypotension.
Topics: Adult; Anesthesia; Blood Pressure; Calcium Channel Blockers; Diltiazem; Female; Heart Rate; Hip; Humans; Hypotension, Controlled; Male; Middle Aged; Nicardipine; Sympathetic Nervous System | 1999 |
Effects of intracoronary nicardipine, diltiazem and verapamil on coronary blood flow.
Topics: Aged; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Coronary Vessels; Diltiazem; Double-Blind Method; Female; Humans; Injections; Male; Middle Aged; Nicardipine; Verapamil | 2000 |
The effect of calcium channel blockers on cerebral oxygenation during tracheal extubation.
Topics: Blood Pressure; Brain; Calcium Channel Blockers; Cerebrovascular Circulation; Diltiazem; Double-Blind Method; Female; Gynecologic Surgical Procedures; Heart Rate; Humans; Intubation, Intratracheal; Nicardipine; Oxygen; Oxyhemoglobins; Spectroscopy, Near-Infrared; Vasodilation | 2000 |
Combined administration of diltiazem and nicardipine attenuates hypertensive responses to emergence and extubation.
Topics: Aged; Anesthesia; Anesthesia Recovery Period; Antihypertensive Agents; Blood Pressure; Diltiazem; Drug Combinations; Female; Heart Rate; Humans; Hypertension; Intubation, Intratracheal; Male; Middle Aged; Neurosurgical Procedures; Nicardipine; Postoperative Period | 2002 |
Nitric oxide plays an insignificant role in direct vasodilator effects of calcium channel blockers in healthy humans.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diltiazem; Endothelium, Vascular; Enzyme Inhibitors; Forearm; Heart Rate; Humans; Male; Nicardipine; Nifedipine; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Plethysmography; Vasodilation; Vasodilator Agents | 2002 |
Effects of nicardipine and diltiazem on the bispectral index and 95% spectral edge frequency.
Topics: Adult; Aged; Analysis of Variance; Anesthesia, Intravenous; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Electroencephalography; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Monitoring, Intraoperative; Nicardipine; Time Factors | 2003 |
Effects of diltiazem on sympathetic activity in patients with aneurysmal subarachnoid hemorrhage.
Topics: Acute Disease; Aged; Calcium Channel Blockers; Diltiazem; Female; Humans; Male; Middle Aged; Nicardipine; Prospective Studies; Subarachnoid Hemorrhage; Sympathetic Nervous System; Treatment Outcome; Vasospasm, Intracranial | 2015 |
161 other study(ies) available for diltiazem and nicardipine
| Article | Year |
|---|---|
Novel calcium antagonists. Synthesis and structure-activity relationship studies of benzothiazoline derivatives.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Pulmonary Embolism; Rabbits; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Thiazoles | 1988 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine | 2002 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
New functional assay of P-glycoprotein activity using Hoechst 33342.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluoresceins; Humans; Microscopy, Fluorescence; Molecular Structure; Principal Component Analysis; Time Factors | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structure-activity relationships of new inhibitors of breast cancer resistance protein (ABCG2).
Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Humans; Models, Molecular; Molecular Structure; Neoplasm Proteins; Phthalic Acids; Quantitative Structure-Activity Relationship; Quinolines; Reproducibility of Results; Stereoisomerism; Time Factors; Tumor Cells, Cultured | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Effect of [6]-shogaol on cytosolic Ca2+ levels and proliferation in human oral cancer cells (OC2).
Topics: Calcium; Calcium Channels, L-Type; Catechols; Cell Line, Tumor; Cytosol; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Estrenes; Humans; Inositol 1,4,5-Trisphosphate; Molecular Structure; Mouth Neoplasms; Phospholipase A2 Inhibitors; Protein Kinase C; Pyrrolidinones; Thapsigargin | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers | 2012 |
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
[Affinity of Z-105 to the 1,4-dihydropyridine type calcium channel and several other receptor bindings in the central nervous system].
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; In Vitro Techniques; Male; Nicardipine; Nitrophenols; Organophosphorus Compounds; Radioligand Assay; Rats; Receptors, Neurotransmitter; Tritium | 1992 |
Inhibition of sodium pump by bepridil. An in vitro and microcalorimetric study.
Topics: Adenosine Triphosphate; Bepridil; Diltiazem; Erythrocytes; Humans; Kinetics; Nicardipine; Nifedipine; Ouabain; Potassium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1992 |
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil | 1992 |
Differential potentiation by calcium antagonists of neuromuscular blockade induced by pancuronium and succinylcholine in cats in vivo.
Topics: Animals; Calcium Channel Blockers; Cats; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Female; Male; Neuromuscular Blocking Agents; Nicardipine; Pancuronium; Stereoisomerism; Succinylcholine; Verapamil | 1992 |
[Adrenal catecholamine releases during hypotension with continuous administration of calcium entry blockers and nitroglycerin].
Topics: Adrenal Glands; Animals; Diltiazem; Dogs; Epinephrine; Hypotension; Male; Nicardipine; Nitroglycerin; Norepinephrine | 1992 |
Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells. Correlation of protection with preservation of glutathione levels.
Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Calcium Channel Blockers; Cattle; Cell Survival; Cells, Cultured; Diltiazem; Endothelium, Vascular; Free Radicals; Glutathione; Lipid Peroxidation; Nicardipine; Nifedipine; Sarcolemma; Verapamil | 1992 |
Effects of calcium channel blockers on formalin-induced nociception and inflammation in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Diltiazem; Formaldehyde; Hindlimb; Inflammation; Male; Nicardipine; Nitrendipine; Pain; Pain Measurement; Rats; Verapamil | 1992 |
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil | 1991 |
Do calcium channel blockers have any influence on the immunological status of renal graft recipients on ciclosporin therapy?
Topics: Adjuvants, Immunologic; Adult; Cyclosporins; Diltiazem; Epitopes; Female; Humans; Kidney Transplantation; Leukocyte Count; Lymphocyte Activation; Male; Middle Aged; Nicardipine; Phenylhydrazines; T-Lymphocytes; T-Lymphocytes, Regulatory | 1990 |
Inhibitory effects of diltiazem, verapamil, nifedipine, and nicardipine on sympathetic tachycardia in decentralized hearts of anesthetized dogs.
Topics: Analysis of Variance; Animals; Blood Pressure; Coronary Circulation; Diltiazem; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Male; Nicardipine; Nifedipine; Pentobarbital; Sympathetic Nervous System; Tachycardia; Verapamil | 1990 |
Differential effects of L-type calcium channel blockers and stimulants on naloxone-precipitated withdrawal in mice acutely dependent on morphine.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Female; Mice; Morphine Dependence; Naloxone; Nicardipine; Postural Balance; Substance Withdrawal Syndrome; Verapamil | 1991 |
Effect of endothelin-1 on guinea pig gallbladder smooth muscle in vitro.
Topics: Animals; Arachidonic Acid; Atropine; Calcium; Cations, Divalent; Diltiazem; Endothelins; Gallbladder; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Neurotoxins; Nicardipine; Strontium | 1992 |
Effects of Ca2+ antagonists on NA-induced intracellular Ca2+ mobilization in rat cultured neurons.
Topics: Animals; Calcium; Cells, Cultured; Diltiazem; Frontal Lobe; Intracellular Fluid; Neurons; Nicardipine; Norepinephrine; Prazosin; Rats; Verapamil | 1991 |
Protection against ischaemic ventricular fibrillation by blocking agents of myocardial cell calcium influx. Electrophysiological study in the pig in situ heart.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Diltiazem; Electrophysiology; Myocardium; Nicardipine; Sarcolemma; Swine; Ventricular Fibrillation; Verapamil | 1991 |
Effect of TC-81, a new dihydropyridine derivative, on K(+)-induced contraction in rat aorta.
Topics: Animals; Aorta; Calcium; Calcium Radioisotopes; Dihydropyridines; Diltiazem; In Vitro Techniques; Isometric Contraction; Male; Nicardipine; Nifedipine; Papaverine; Potassium; Rats; Rats, Inbred Strains; Vasoconstriction; Vasodilator Agents | 1991 |
Endothelin-1 stimulates prostaglandin E2 production in an extracellular calcium-independent manner in cultured rat mesangial cells.
Topics: Animals; Calcium; Cells, Cultured; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; Endothelins; Fura-2; Glomerular Mesangium; Hemodynamics; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Male; Nicardipine; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Endothelin | 1991 |
Effect of calcium channel blocking agents on the reductive metabolism of halothane.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Halothane; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nicardipine; Oxidation-Reduction; Verapamil | 1991 |
Direct measurement of intracellular free calcium in cultured human puerperal myometrial cells stimulated by oxytocin: effects of extracellular calcium and calcium channel blockers.
Topics: Calcium; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Female; Humans; Microscopy, Fluorescence; Myometrium; Nicardipine; Nifedipine; Nitrendipine; Oxytocin; Postpartum Period | 1991 |
Cardiovascular characterization of SD-3211, a novel benzothiazine calcium channel blocker, in isolated rabbit hearts.
Topics: Animals; Calcium Channel Blockers; Cardiovascular System; Coronary Circulation; Diltiazem; Female; Heart; Male; Myocardial Contraction; Nicardipine; Perfusion; Rabbits; Thiazoles | 1991 |
The enhancement of myocardial protection through an acalcemic storage solution containing nicardipine, a potent calcium channel blocker. A basic study using rat ventricular myocytes.
Topics: Animals; Calcium; Diltiazem; Heart; Heart Transplantation; Male; Myocardium; Nicardipine; Organ Preservation; Rats | 1991 |
Heterogeneous interference of nicardipine, verapamil, and diltiazem with forearm arteriolar responsiveness to adrenergic stimulation in hypertensive patients.
Topics: Arterioles; Diltiazem; Female; Forearm; Humans; Hypertension; Lower Body Negative Pressure; Male; Nicardipine; Norepinephrine; Propranolol; Regional Blood Flow; Vasoconstriction; Vasodilation; Verapamil | 1991 |
Protective effects of calcium channel blockers on hydrogen peroxide induced increases in endothelial permeability.
Topics: Albumins; Calcium Channel Blockers; Capillary Permeability; Cell Membrane Permeability; Cells, Cultured; Diltiazem; Electric Conductivity; Endothelium, Vascular; Humans; Hydrogen Peroxide; Nicardipine; Nifedipine; Verapamil | 1990 |
Tissue selectivity of the novel calcium antagonist sesamodil fumarate in isolated smooth muscles and cardiac muscles.
Topics: Animals; Calcimycin; Calcium Channel Blockers; Diltiazem; Guinea Pigs; Heart; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nicardipine; Nifedipine; Rabbits; Swine; Thiazoles; Verapamil | 1990 |
Inhibitory effects of endothelial cells and calcium channel blockers on platelet aggregation.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine Diphosphate; Aspirin; Blood Platelets; Bone Marrow Cells; Calcium Channel Blockers; Collagen; Diltiazem; Endothelium, Vascular; Epoprostenol; Fibroblasts; Humans; Nicardipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombin; Thromboxane A2; Verapamil | 1990 |
[Comparison of pro-edematous effects of 2 calcium antagonists in bilaterally nephrectomized rats].
Topics: Albumins; Animals; Diltiazem; Edema; Extracellular Space; Hematocrit; Hemodynamics; Hypertension; Male; Nephrectomy; Nicardipine; Rats; Rats, Inbred Strains | 1990 |
Actions of Ca2+ antagonists on two types of Ca2+ channels in rat aorta smooth muscle cells in primary culture.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Electric Conductivity; Flunarizine; Kinetics; Male; Membrane Potentials; Muscle, Smooth, Vascular; Nicardipine; Rats; Time Factors; Verapamil | 1990 |
Nicergoline inhibits T-type Ca2+ channels in rat isolated hippocampal CA1 pyramidal neurones.
Topics: Animals; Calcium Channels; Diltiazem; Hippocampus; In Vitro Techniques; Membrane Potentials; Neurons; Nicardipine; Nicergoline; Pyramidal Tracts; Rats | 1990 |
Stretch may enhance the release of endothelium-derived relaxing factor in rabbit aorta.
Topics: Animals; Aorta; Calcium; Calcium Channels; Cyclic GMP; Diltiazem; Endothelium, Vascular; Male; Nicardipine; Nitric Oxide; Physical Stimulation; Rabbits; Radioimmunoassay | 1990 |
Antidepressant-like action of nicardipine, verapamil and hemicholinium-3 injected into the anterior hypothalamus in the rat forced swim test.
Topics: Animals; Antidepressive Agents; Diltiazem; Hemicholinium 3; Hypothalamus, Anterior; Injections; Male; Motor Activity; Nicardipine; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Effect of endothelins on cytosolic free calcium concentration in neuroblastoma NG108-15 and NCB-20 cells.
Topics: Animals; Bradykinin; Calcium; Cricetinae; Cytosol; Diltiazem; Endothelins; Fluorescent Dyes; Fluorometry; Fura-2; Homeostasis; Hybrid Cells; Mice; Neuroblastoma; Neurons; Nicardipine; Rats; Tumor Cells, Cultured | 1990 |
Plasmodium chabaudi: in vivo effects of Ca2+ antagonists on chloroquine-resistant and chloroquine-sensitive parasites.
Topics: Animals; Calcium Channel Blockers; Chloroquine; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Drug Therapy, Combination; Female; Malaria; Mice; Mice, Inbred ICR; Nicardipine; Plasmodium; Verapamil | 1990 |
[Effects of cardioplegic solution and calcium entry blockers on coronary artery contraction].
Topics: Animals; Calcium Channel Blockers; Cardioplegic Solutions; Coronary Vasospasm; Diltiazem; Dogs; Nicardipine; Nifedipine; Potassium; Potassium Compounds; Verapamil | 1990 |
Class IV Ca2+ antagonists do not affect lipid peroxidation in singlet oxygen challenged cardiomyocytes.
Topics: Animals; Benzothiazoles; Calcium Channel Blockers; Cell Separation; Cinnarizine; Diltiazem; Flunarizine; Lidoflazine; Lipid Peroxidation; Malondialdehyde; Myocardium; Nicardipine; Oxygen; Piperidines; Rats; Thiazoles; Verapamil | 1990 |
Effect of different calcium antagonists on transcapillary fluid shift.
Topics: Animals; Blood Proteins; Calcium Channel Blockers; Capillary Permeability; Diltiazem; Evans Blue; Hematocrit; Male; Nephrectomy; Nicardipine; Osmolar Concentration; Rats; Rats, Inbred Strains; Serum Albumin | 1990 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to high KCl.
Topics: 1-Methyl-3-isobutylxanthine; Anesthetics, Local; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Phentolamine; Potassium Chloride; Saphenous Vein; Verapamil | 1985 |
Blocking actions of Ca2+ antagonists on the Ca2+ channels in the smooth muscle cell membrane of rabbit small intestine.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Intestine, Small; Ion Channels; Muscle, Smooth; Nicardipine; Rabbits; Verapamil | 1987 |
Effects of Ca2+ agonist and antagonists on cytosolic free Ca2+ concentration: studies on Ca2+ channels in rat parotid cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Ion Channels; Kinetics; Male; Methoxamine; Nicardipine; Parotid Gland; Potassium; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Prolonged inhibitory effects of nilvadipine (FR34235) following washout in isolated rabbit aorta and mesenteric artery.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Diltiazem; Female; In Vitro Techniques; Male; Mesenteric Arteries; Nicardipine; Nifedipine; Norepinephrine; Potassium Chloride; Rabbits; Vasodilator Agents | 1988 |
Differential effects of verapamil, nicardipine and diltiazem on Ca2+-dependent and Ca2+-independent noradrenaline release and contraction in isolated canine saphenous veins.
Topics: Animals; Calcium; Diltiazem; Dogs; Female; In Vitro Techniques; Ion Channels; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Saphenous Vein; Tetracaine; Tetraethylammonium Compounds; Verapamil | 1988 |
Nicardipine inhibits axon conduction but causes dual changes of acetylcholine release in the mouse motor nerve.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Axonal Transport; Axons; Chick Embryo; Diaphragm; Diltiazem; Female; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Motor Neurons; Muscle Contraction; Nicardipine; Nifedipine; Sodium Channels; Succinylcholine; Verapamil | 1989 |
Vascular endothelial cell migration in vitro roles of cyclic nucleotides, calcium ion and cytoskeletal system.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Aorta, Thoracic; Bucladesine; Calcium Channel Blockers; Cattle; Cell Movement; Cells, Cultured; Colchicine; Cytochalasin B; Diltiazem; Endothelium, Vascular; Fetus; Gallic Acid; Nicardipine; Sulfonamides; Theophylline; Trifluoperazine | 1989 |
Desmethoxyverapamil-sensitive calcium channels in rat portal vein smooth muscle.
Topics: Animals; Calcium Channels; Diltiazem; In Vitro Techniques; Membranes; Muscle, Smooth, Vascular; Nicardipine; Portal Vein; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Voltage dependent calcium channel expression in isolated osteoclasts.
Topics: Animals; Calcium Channels; Cell Membrane; Cells, Cultured; Chickens; Diltiazem; Electrophysiology; Female; Nicardipine; Osteoclasts; Potassium Chloride; Verapamil | 1989 |
[Calcium antagonists in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
In vivo characterization of combination antitumor chemotherapy with calcium channel blockers and cis-diamminedichloroplatinum(II).
Topics: Animals; Calcium Channel Blockers; Cisplatin; Diltiazem; Drug Evaluation, Preclinical; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Imidazoles; Lung Neoplasms; Melanoma, Experimental; Mice; Nicardipine; Nifedipine; Trifluoperazine; Verapamil | 1989 |
Teratogenic effects of some calcium channel blocking agents in Xenopus embryos.
Topics: Abnormalities, Drug-Induced; Animals; Calcium Channel Blockers; Diltiazem; Nicardipine; Verapamil; Xenopus | 1989 |
Effects of calcium channel blockers and hydralazine on epinephrine-induced hyperglycemia in vivo.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Epinephrine; Food Deprivation; Glucose Tolerance Test; Hydralazine; Hyperglycemia; Male; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Calcium channel antagonists and cyclosporine metabolism: in vitro studies with human liver microsomes.
Topics: Adult; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Cyclosporins; Diltiazem; Female; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Nicardipine; Radioimmunoassay; Verapamil | 1989 |
Suppression of clofibrate-induced peroxisome proliferation in rat liver by nicardipine, a calcium antagonist.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Acyl-CoA Dehydrogenase; Animals; Carnitine O-Acetyltransferase; Carnitine O-Palmitoyltransferase; Catalase; Clofibrate; D-Amino-Acid Oxidase; Diltiazem; Enoyl-CoA Hydratase; Enzyme Induction; Enzyme Inhibitors; Fatty Acid Desaturases; Liver; Male; Microbodies; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Triglycerides | 1988 |
Evaluation of different drugs in two models of immediate hypersensitivity.
Topics: Animals; Cromolyn Sodium; Diethylcarbamazine; Diltiazem; Female; Guinea Pigs; Histamine H1 Antagonists; Hypersensitivity, Immediate; In Vitro Techniques; Isometric Contraction; Male; Nicardipine; Ovalbumin; Passive Cutaneous Anaphylaxis; Quinazolines; Trachea; Verapamil | 1988 |
Characterization of volume-sensitive, calcium-permeating pathways in the osteosarcoma cell line UMR-106-01.
Topics: Calcium; Cell Membrane Permeability; Cytosol; Diltiazem; Electric Conductivity; Kinetics; Lanthanum; Membrane Potentials; Nicardipine; Osmolar Concentration; Osteoblasts; Osteosarcoma; Tumor Cells, Cultured; Valinomycin; Verapamil | 1989 |
Differential effects of Ca antagonists on the noradrenaline release and contraction evoked by nerve stimulation in the presence of 4-aminopyridine.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Salicylates; Salicylic Acid; Stereoisomerism; Tetracaine; Tetrodotoxin; Verapamil | 1987 |
Effects of nicardipine and diltiazem on alpha-adrenoceptor responses in canine saphenous veins.
Topics: Animals; Azepines; Diltiazem; Dogs; Female; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Norepinephrine; Receptors, Adrenergic, alpha; Saphenous Vein | 1987 |
Lack of effect of nicardipine and diltiazem on glucose- and arginine-induced insulin release in obese subjects.
Topics: Arginine; Diltiazem; Female; Glucose; Glucose Tolerance Test; Humans; Insulin; Male; Nicardipine; Obesity | 1988 |
Systemic and coronary hemodynamics of labetalol in normotensive patients with ischemic heart disease.
Topics: Coronary Circulation; Coronary Disease; Diltiazem; Hemodynamics; Humans; Labetalol; Nicardipine | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Injections, Intravenous; Male; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Rats; Rats, Inbred SHR; Verapamil | 1988 |
[Controlled hypotension: a future indication for calcium inhibitors?].
Topics: Anesthesia, General; Blood Pressure; Calcium Channel Blockers; Diltiazem; Humans; Hypotension, Controlled; Nicardipine; Nifedipine; Postoperative Period; Verapamil | 1988 |
Effects of Ca++-antagonists on systemic capacitance vessels and venous return curves of dogs--a study with mean circulatory pressure.
Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Calcium Channel Blockers; Cardiac Output; Diltiazem; Dogs; Hematocrit; Infusions, Intravenous; Nicardipine; Nifedipine; Norepinephrine; Reproducibility of Results; Vascular Resistance; Verapamil | 1988 |
Differential effects of calcium channel blocking agents on pancuronium- and suxamethonium-induced neuromuscular blockade.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Drug Synergism; Female; In Vitro Techniques; Muscle Contraction; Neuromuscular Junction; Nicardipine; Pancuronium; Rats; Rats, Inbred Strains; Succinylcholine; Verapamil | 1988 |
Comparison of the effects of calcium channel blockers and antiarrhythmic drugs on digitalis-induced oscillatory afterpotentials on canine Purkinje fiber.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Digitalis; Diltiazem; Dogs; Electric Stimulation; Female; Heart Conduction System; Male; Mexiletine; Nicardipine; Nifedipine; Nitrendipine; Plants, Medicinal; Plants, Toxic; Procainamide; Propranolol; Purkinje Fibers; Verapamil | 1987 |
Compared effects of calcium entry blockers on calcium-induced tension in rat isolated cerebral and peripheral resistance vessels.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Arteries; Diltiazem; Female; In Vitro Techniques; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Serotonin; Vascular Resistance; Verapamil | 1987 |
[Cancer chemotherapy combined with a calcium antagonist in patients with hematologic malignancies and solid tumors resistant to standard chemotherapy].
Topics: Acute Disease; Administration, Oral; Antibiotics, Antineoplastic; Diltiazem; Drug Therapy, Combination; Esophageal Neoplasms; Humans; Leukemia; Lymphoma; Naphthacenes; Nicardipine; Remission Induction; Vinca Alkaloids | 1987 |
Absence of effect of calcium antagonists on endothelium-dependent relaxation in rabbit aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Endothelium; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Nicardipine; Nitric Oxide; Rabbits; Vasodilator Agents | 1987 |
Effects of calcium-antagonists and calmodulin inhibitors on DNA synthesis in cultured rat vascular smooth muscle cells.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cells, Cultured; Diltiazem; DNA Replication; Dose-Response Relationship, Drug; Epidermal Growth Factor; Male; Muscle, Smooth, Vascular; Nicardipine; Platelet-Derived Growth Factor; Rats; Rats, Inbred Strains; Sulfonamides; Trifluoperazine; Verapamil | 1987 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Male; Nicardipine; Nifedipine; Pyrrolidines; Sinoatrial Node; Verapamil | 1987 |
The mechanism of centrally mediated cardiovascular actions of the three structurally different calcium antagonists, verapamil, diltiazem and nicardipine, in rats.
Topics: Animals; Blood Pressure; Brain; Cardiovascular System; Diltiazem; Heart Rate; Injections, Intravenous; Injections, Intraventricular; Male; Nicardipine; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Effect of calcium antagonists on adrenergic mechanisms in canine saphenous veins.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Sympathetic Nervous System; Tyramine | 1986 |
Effect of calcium antagonists on reactive hypoglycemia associated with hyperinsulinemia.
Topics: Adult; Aged; C-Peptide; Calcium Channel Blockers; Diltiazem; Female; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypoglycemia; Male; Middle Aged; Nicardipine; Nifedipine | 1986 |
The calcium entry blockers: anti-manic drugs?
Topics: Amphetamines; Animals; Bipolar Disorder; Calcium Channel Blockers; Diltiazem; Hyperkinesis; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicardipine; Oxolinic Acid; Reserpine; Verapamil | 1986 |
Isolated rat cardiac myocytes as an experimental model to study calcium overload: the effect of calcium-entry blockers.
Topics: Animals; Calcium; Calcium Channel Blockers; Cinnarizine; Diltiazem; Flunarizine; Heart; Lidoflazine; Male; Myocardial Contraction; Myocardium; Nicardipine; Nifedipine; Rats; Rats, Inbred Strains; Time Factors; Verapamil; Veratrine | 1986 |
Effects of calcium antagonists on smooth muscle membranes of the canine stomach.
Topics: Action Potentials; Animals; Atropine; Calcium Channel Blockers; Cell Membrane; Choline; Diltiazem; Dogs; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Male; Muscle, Smooth; Nicardipine; Nifedipine; Stomach | 1985 |
[Effect of calcium antagonists on the portal vein].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Carbon Tetrachloride Poisoning; Cats; Diltiazem; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Portal Vein; Regional Blood Flow | 1985 |
Tissue response selectivity of calcium antagonists is not due to heterogeneity of [3H]-nitrendipine binding sites.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Diltiazem; Female; Gallopamil; In Vitro Techniques; Isometric Contraction; Kinetics; Membranes; Muscle, Smooth, Vascular; Myocardium; Nicardipine; Nifedipine; Organ Specificity; Rabbits; Receptors, Nicotinic; Verapamil | 1984 |
Effects of nicardipine and other Ca2+-antagonists on catecholamine transport into chromaffin granule membrane vesicles.
Topics: Animals; Biological Transport; Calcium Channel Blockers; Catecholamines; Cattle; Chromaffin Granules; Chromaffin System; Diltiazem; In Vitro Techniques; Intracellular Membranes; Nicardipine; Nifedipine; Norepinephrine | 1984 |
Effects of nicardipine, nifedipine, verapamil, and diltiazem on urine volume, sodium and potassium excretion and plasma aldosterone levels in the rat.
Topics: Aldosterone; Animals; Calcium Channel Blockers; Diltiazem; Kidney; Male; Natriuresis; Nicardipine; Nifedipine; Potassium; Rats; Rats, Inbred WKY; Urine; Verapamil | 1984 |
Ineffectiveness of Ca2+-antagonists nicardipine and diltiazem on experimental atherosclerosis in cholesterol-fed rabbits.
Topics: Animals; Aorta; Arteriosclerosis; Benzazepines; Calcium; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Diltiazem; Kidney; Liver; Male; Nicardipine; Nifedipine; Phospholipids; Rabbits; Triglycerides | 1984 |
[Sustained-release pellet of vasodilators--basic experiment].
Topics: Delayed-Action Preparations; Diltiazem; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Nicardipine; Nifedipine; Papaverine; Rupture, Spontaneous; Silicone Elastomers; Subarachnoid Hemorrhage; Temperature | 1984 |
Effects of five different organic calcium antagonists on guinea-pig isolated trachea.
Topics: Animals; Anti-Arrhythmia Agents; Bepridil; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nicardipine; Nifedipine; Pyrrolidines; Trachea; Verapamil | 1984 |
Effects of Ca antagonists on the norepinephrine release and contractile responses of isolated canine saphenous veins to transmural nerve stimulation.
Topics: Adrenergic Fibers; Animals; Calcium; Calcium Channel Blockers; Diltiazem; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Tritium; Verapamil | 1984 |
Calcium antagonist and the peripheral circulation: differences and similarities between PY 108-068, nicardipine, verapamil and diltiazem.
Topics: Animals; Calcium Channel Blockers; Cats; Diltiazem; Hemodynamics; Microspheres; Neural Conduction; Nicardipine; Nifedipine; Regional Blood Flow; Verapamil | 1983 |
Calcium channel blockers in chronic stable angina. A review.
Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Diltiazem; Electrocardiography; Humans; Nicardipine; Nifedipine; Verapamil | 1982 |
Nicardipine may impair glucose metabolism in hypertensive diabetic patients.
Topics: Adult; Aged; Atenolol; Carteolol; Diabetes Mellitus, Type 2; Diltiazem; Enalapril; Female; Glucose; Glycated Hemoglobin; Humans; Hypertension; Male; Metoprolol; Middle Aged; Nicardipine; Propanolamines | 1994 |
Protective effect of some calcium antagonists against mitochondrial calcium injury.
Topics: Adenosine Triphosphate; Amlodipine; Animals; Antihypertensive Agents; Bepridil; Calcium Channel Blockers; Diltiazem; In Vitro Techniques; Male; Mitochondria, Liver; Myocardial Ischemia; Nicardipine; Rats; Rats, Wistar; Verapamil | 1994 |
Effect of intravenous calcium antagonists on left ventricular diastolic function in hypertension: assessed by pulsed-Doppler echocardiogram.
Topics: Calcium Channel Blockers; Diastole; Diltiazem; Echocardiography, Doppler, Pulsed; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; Ventricular Function, Left | 1995 |
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Dibenzothiepins; Diltiazem; Dogs; Female; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nicardipine; Nifedipine; Piperazines; Rats; Rats, Inbred SHR; Rats, Wistar | 1993 |
Investigation and optimisation of the use of micellar electrokinetic chromatography for the analysis of six cardiovascular drugs.
Topics: Amlodipine; Atenolol; Cardiovascular Agents; Chromatography; Diltiazem; Electrochemistry; Hydrogen-Ion Concentration; Kinetics; Micelles; Nicardipine; Nifedipine; Osmosis; Sodium Dodecyl Sulfate; Verapamil | 1995 |
The effects of calcium antagonists and prostaglandin E1 on isolated canine coronary arterial tension.
Topics: Alprostadil; Animals; Calcium; Calcium Channel Blockers; Coronary Vessels; Data Interpretation, Statistical; Diltiazem; Dogs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Potassium; Sodium; Solutions; Verapamil | 1994 |
Antioxidant activity of calcium channel blocking drugs.
Topics: Animals; Antioxidants; Aorta; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Diltiazem; Dogs; Endothelium, Vascular; Free Radicals; Glutathione; Heart Ventricles; Isomerism; Kinetics; Lipid Peroxidation; Malondialdehyde; Myocardium; Nicardipine; Nifedipine; Sarcolemma; Verapamil | 1994 |
Control of systemic hypertension with diltiazem, a calcium-antagonist, in patients with a mildly elevated intracranial pressure: a comparative study.
Topics: Aged; Craniotomy; Diltiazem; Humans; Hypertension; Intracranial Pressure; Middle Aged; Nicardipine; Nitroglycerin; Retrospective Studies | 1994 |
Inotropic effects of ryanodine and calcium antagonists on embryonic and hatched chick myocardium.
Topics: Animals; Calcium; Calcium Channel Blockers; Chick Embryo; Chickens; Depression, Chemical; Diltiazem; Electric Stimulation; Heart; In Vitro Techniques; Manganese; Myocardial Contraction; Nicardipine; Ryanodine; Sensitivity and Specificity; Stimulation, Chemical | 1993 |
[The effects of calcium antagonists on prostaglandin E2 reaction in rabbit eyes].
Topics: Animals; Aqueous Humor; Calcium Channel Blockers; Diltiazem; Dinoprostone; Eye; Eye Proteins; Intraocular Pressure; Male; Nicardipine; Rabbits; Verapamil | 1994 |
Relation between blood pressure and plasma catecholamine concentration after administration of calcium antagonists to rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diltiazem; Heart Rate; Nicardipine; Rats; Rats, Sprague-Dawley; Verapamil | 1994 |
Inhibitor effects of diltiazem, nicardipine, nifedipine and verapamil on the norepinephrine-induced contractions of the canine saphenous vein in calcium-free medium.
Topics: Animals; Calcium; Calcium Channel Blockers; Culture Media; Diltiazem; Dogs; Electrophysiology; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Norepinephrine; Saphenous Vein; Verapamil | 1994 |
Cholinergic neuromuscular transmission in the longitudinal muscle of the guinea-pig ileum.
Topics: Action Potentials; Animals; Calcium; Cholinergic Fibers; Diltiazem; Electric Stimulation; Electrophysiology; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Nicardipine; Potassium; Synaptic Transmission; Verapamil | 1993 |
[The pathogenesis and the preventive treatment of cerebral vasospasm following subarachnoid hemorrhage--especially clinical and pharmacological effect of Ca++ antagonist for vasospasm].
Topics: Animals; Calcium Channel Blockers; Cattle; Cerebrovascular Circulation; Diltiazem; Humans; Ischemic Attack, Transient; Nicardipine; Subarachnoid Hemorrhage; Treatment Outcome | 1993 |
[Effects of calcium antagonists on prostaglandin E2 production in cultured human amnion cells].
Topics: Amnion; Calcium Channel Blockers; Cells, Cultured; Depression, Chemical; Diltiazem; Dinoprostone; Dose-Response Relationship, Drug; Egtazic Acid; Female; Humans; Interleukin-1; Nicardipine; Nifedipine; Phospholipases A; Phospholipases A2; Pregnancy; Verapamil | 1994 |
[Comparison between diltiazem and nicardipine used during anesthesia for coronary revascularization].
Topics: Aged; Anesthesia, Inhalation; Depression, Chemical; Diltiazem; Female; Fentanyl; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Ischemia; Myocardial Revascularization; Nicardipine | 1994 |
Effect of pinaverium and other calcium channel blockers on contraction of isolated gastric antral smooth muscle cells caused by gastrointestinal hormones.
Topics: Animals; Calcium; Calcium Channel Blockers; Diltiazem; Gastrins; Gastrointestinal Hormones; In Vitro Techniques; Morpholines; Motilin; Muscle Contraction; Muscle, Smooth; Nicardipine; Pyloric Antrum; Rabbits; Sincalide | 1994 |
Potentiation of antinociceptive effects of morphine by calcium-channel blockers at the level of the spinal cord.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Drug Synergism; Injections, Spinal; Male; Morphine; Nicardipine; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord; Verapamil | 1993 |
[Interaction of cardiovascular effect of calcium channel blocking drugs and those of inhalation anesthetics in humans].
Topics: Adult; Aged; Anesthetics; Diltiazem; Drug Interactions; Ethers; Female; Hemodynamics; Humans; Isoflurane; Male; Methyl Ethers; Middle Aged; Nicardipine; Sevoflurane | 1993 |
The interference by nicardipine and diltiazem on alpha-adrenergic receptor-mediated vasoconstriction in isolated human subcutaneous arterioles.
Topics: Adult; Aged; Arterioles; Diltiazem; Endothelins; Female; Humans; In Vitro Techniques; Male; Middle Aged; Nicardipine; Norepinephrine; Receptors, Adrenergic, alpha; Vasoconstriction | 1993 |
[Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension].
Topics: Anesthesia, Intravenous; Calcium Channel Blockers; Diltiazem; Droperidol; Female; Fentanyl; Humans; Hypertension; Intraoperative Complications; Ketamine; Male; Middle Aged; Nicardipine; Nifedipine | 1993 |
Effects of antidotes to cocaine on the deregulation of the baroreflex by the alkaloid.
Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antidotes; Baroreflex; Blood Pressure; Cocaine; Diltiazem; Enalaprilat; Nicardipine; Rats; Rats, Sprague-Dawley | 1996 |
Calcium channel blockers induce thymic apoptosis in vivo in rats.
Topics: Animals; Apoptosis; Calcium Channel Blockers; Chlorpromazine; Diltiazem; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Hydrocortisone; Hypotension; Image Processing, Computer-Assisted; Injections, Intraperitoneal; Male; Microscopy, Electron; Nicardipine; Nifedipine; Nitroprusside; Organ Size; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; T-Lymphocytes; Thymus Gland; Verapamil | 1996 |
Effects of calcium antagonists on hepatic and systemic hemodynamics in awake portal hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Consciousness; Diltiazem; Hemodynamics; Hypertension, Portal; Liver Circulation; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Time Factors; Vascular Resistance | 1996 |
Porcine gastroepiploic artery as an in vitro experimental model to study vasodilators in microsurgery.
Topics: Animals; Arteries; Culture Techniques; Diltiazem; Microsurgery; Nicardipine; Spasm; Swine; Vasodilator Agents; Verapamil | 1996 |
Role of taste aversion in calcium channel inhibitor-induced suppression of saccharin and alcohol drinking in rats.
Topics: Alcohol Drinking; Animals; Avoidance Learning; Calcium Channel Blockers; Conditioning, Classical; Diltiazem; Dose-Response Relationship, Drug; Drinking; Isradipine; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Saccharin; Taste | 1996 |
Temporal variation in the interaction between calcium channel blockers and morphine-induced analgesia.
Topics: Analgesia; Animals; Calcium Channel Blockers; Circadian Rhythm; Diltiazem; Drug Synergism; Male; Mice; Mice, Inbred BALB C; Morphine; Nicardipine; Pain; Verapamil | 1996 |
Effects of calcium antagonists on binding of local anesthetics to plasma proteins and erythrocytes in mice.
Topics: Anesthetics, Local; Animals; Blood Proteins; Bupivacaine; Calcium Channel Blockers; Diltiazem; Erythrocytes; In Vitro Techniques; Lidocaine; Male; Mice; Nicardipine; Protein Binding; Verapamil | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Comparison of the sympathetic nervous system activity between spontaneously hypertensive and Wistar-Kyoto rats to respond to blood pressure reduction.
Topics: Animals; Baroreflex; Blood Pressure; Calcium Channel Blockers; Diltiazem; Epinephrine; Male; Nicardipine; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System | 1997 |
A comparison of the uricosuric effects in rats of diltiazem and derivatives of dihydropyridine (nicardipine and nifedipine).
Topics: Animals; Blood Pressure; Diltiazem; Heart Rate; Inulin; Male; Nicardipine; Nifedipine; Rats; Rats, Wistar; Renal Circulation; Uric Acid; Uricosuric Agents; Urodynamics | 1997 |
Reversal of abnormal coronary vasomotion by calcium antagonists in patients with hypercholesterolemia.
Topics: Calcium Channel Blockers; Case-Control Studies; Coronary Angiography; Coronary Vessels; Diltiazem; Exercise Test; Female; Hemodynamics; Humans; Hypercholesterolemia; Male; Middle Aged; Nicardipine; Treatment Outcome; Vasomotor System | 1998 |
Measurement of intracellular Ca2+ concentration changes by use of fura-2 in the generation of myogenic contraction of dog cerebral artery in response to quick stretch.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Arteries; Diltiazem; Dogs; Female; Fluorescent Dyes; Fura-2; Intracellular Fluid; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Reflex, Stretch; Stress, Mechanical | 1998 |
Rational use of calcium-channel antagonists in Raynaud's phenomenon.
Topics: Amlodipine; Calcium Channel Blockers; Diltiazem; Felodipine; Humans; Isradipine; Nicardipine; Nifedipine; Raynaud Disease | 1998 |
Effects of Ca2+ channel blockers on apomorphine, bromocriptine and morphine-induced locomotor activity in mice.
Topics: Amlodipine; Animals; Apomorphine; Benzazepines; Bromocriptine; Calcium Channel Blockers; Diltiazem; Dopamine Antagonists; Female; Haloperidol; Heterocyclic Compounds, 4 or More Rings; Mice; Morphine; Motor Activity; Nicardipine; Time Factors; Verapamil | 1999 |
Effects of long-acting versus short-acting calcium channel blockers among older survivors of acute myocardial infarction.
Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Humans; Male; Myocardial Infarction; Nicardipine; Nifedipine; Proportional Hazards Models; Retrospective Studies; Risk; Survival Analysis; Survivors; Verapamil | 1999 |
Relationship between myocardial cation content and injury in reperfused rat hearts treated with cation channel blockers.
Topics: Animals; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cations; Creatine Kinase; Diltiazem; Dose-Response Relationship, Drug; Glyburide; Heart Ventricles; Hypoglycemic Agents; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Nicardipine; Procainamide; Rats; Rats, Wistar; Tetrodotoxin | 1999 |
Characteristics of heterogeneity in the expression of vasoconstriction in response to N(G)-monomethyl-L-arginine in isolated canine arteries.
Topics: Animals; Arteries; Charybdotoxin; Cyclic GMP; Diltiazem; Dogs; Enzyme Inhibitors; Nicardipine; Nitric Oxide; omega-N-Methylarginine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1999 |
L-cis diltiazem attenuates intracellular Ca(2+) overload by metabolic inhibition in guinea pig myocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Size; Diltiazem; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Heart Ventricles; Male; Nicardipine; Nickel; Nitrendipine; Sodium-Calcium Exchanger; Stereoisomerism; Thiourea; Uncoupling Agents | 1999 |
Comparative study on calcium channel antagonists in the human radial artery: clinical implications.
Topics: Analysis of Variance; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Nicardipine; Nifedipine; Radial Artery; Vasodilator Agents; Verapamil | 2000 |
L-type Ca2+ channels are not involved in coronary endothelial Ca2+ influx mechanism responsible for endothelium-dependent relaxation.
Topics: Analysis of Variance; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Diltiazem; Endothelium, Vascular; Female; Male; Nicardipine; Nitric Oxide; Substance P; Swine; Verapamil | 1999 |
Differential action of spasmolytic vasodilators on platelet aggregation and endothelial cell-dependent anti-aggregation.
Topics: Alprostadil; Animals; Aorta; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Endothelium, Vascular; Nicardipine; Nitroglycerin; Nitroprusside; Papaverine; Pentobarbital; Platelet Aggregation; Platelet Aggregation Inhibitors; Swine; Sympatholytics; Vasodilator Agents | 2000 |
Inhibition by nifedipine of adherence- and activated macrophage-induced death of human gingival fibroblasts.
Topics: Animals; Calcium Channel Blockers; Cell Adhesion; Cell Death; Cell Division; Cell Line; Cells, Cultured; Coculture Techniques; Diltiazem; DNA Fragmentation; Dose-Response Relationship, Drug; Fibroblasts; Gingiva; Humans; Lipopolysaccharides; Macrophages; Nicardipine; Nifedipine; Nitric Oxide; Nitric Oxide Donors; Thymidine; Time Factors; Verapamil | 2001 |
Contraction of human colonic circular smooth muscle cells is inhibited by the calcium channel blocker pinaverium bromide.
Topics: Adult; Aged; Aged, 80 and over; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Colitis; Colon; Diltiazem; Humans; In Vitro Techniques; Middle Aged; Morpholines; Muscle Contraction; Muscle, Smooth; Nicardipine; Potassium Chloride; Protein Subunits; RNA, Messenger; Sincalide | 2001 |
Reversal of preexisting vasospasm in coronary artery conduits.
Topics: Arteries; Calcium Channel Blockers; Coronary Artery Bypass; Coronary Disease; Culture Techniques; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Occlusion, Vascular; Humans; Nicardipine; Nifedipine; Nitroglycerin; Vasoconstriction; Vasodilation; Veins; Verapamil | 2001 |
Comparative study of calcium-channel blockers on cell proliferation, DNA and collagen syntheses, and EGF receptors of cultured gingival fibroblasts derived from human nifedipine, nicardipine and nisoldipine responders.
Topics: Adult; Aged; Analysis of Variance; Anticonvulsants; Calcium Channel Blockers; Cell Culture Techniques; Cell Division; Collagen; Diltiazem; DNA; ErbB Receptors; Female; Fibroblasts; Flow Cytometry; Gingiva; Gingival Overgrowth; Humans; Male; Middle Aged; Nicardipine; Nifedipine; Nisoldipine; Phenytoin; Radiopharmaceuticals; Statistics as Topic; Tritium; Verapamil | 2001 |
Effect of manganese on guinea pig ventricle: initial depression and late augmentation of contractile force.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Female; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Nicardipine; Ventricular Function | 2002 |
Regulation of structural plasticity by different channel types in rod and cone photoreceptors.
Topics: Ambystoma; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Cobalt; Cyclic GMP; Cyclic Nucleotide-Gated Cation Channels; Diltiazem; Eye Proteins; Ion Channels; Membrane Glycoproteins; Nerve Tissue Proteins; Neurites; Neuronal Plasticity; Nicardipine; Retinal Cone Photoreceptor Cells; Retinal Rod Photoreceptor Cells; Rod Opsins; Synaptic Vesicles; Synaptophysin; Verapamil | 2002 |
High-affinity binding of [3H]DTZ323 to the diltiazem-binding site of L-type Ca2+ channels.
Topics: Alkaloids; Animals; Benzylisoquinolines; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Guinea Pigs; In Vitro Techniques; Male; Muscle, Skeletal; Myocardium; Nicardipine; Rabbits; Radioligand Assay; Time Factors; Verapamil | 2003 |
Effects of three different L-type Ca2+ entry blockers on airway constriction induced by muscarinic receptor stimulation.
Topics: Animals; Bronchoconstriction; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Dogs; Dose-Response Relationship, Drug; Epinephrine; Female; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Nicardipine; Nifedipine; Norepinephrine; Receptors, Muscarinic; Trachea; Verapamil | 2003 |
Effects of diltiazem compared with nicardipine on diaphragmatic fatigability in vivo.
Topics: Animals; Calcium Channel Blockers; Diaphragm; Diltiazem; Dogs; Electric Stimulation; Female; Male; Muscle Contraction; Muscle Fatigue; Nicardipine | 2003 |
Study of drug effects of calcium channel blockers on retinal degeneration of rd mouse.
Topics: Animals; Calcium Channel Blockers; Caspases; Diltiazem; Electroretinography; Fibroblast Growth Factor 2; Gene Expression; Membrane Proteins; Mice; Mice, Mutant Strains; Microscopy, Electron; Nerve Tissue Proteins; Nicardipine; Nifedipine; Photoreceptor Cells, Vertebrate; Retinal Degeneration; Retinitis Pigmentosa; Synaptogyrins | 2004 |
Differences in the inhibition of cytochromes P450 3A4 and 3A5 by metabolite-inhibitor complex-forming drugs.
Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diltiazem; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythromycin; Humans; Microsomes, Liver; Nicardipine | 2004 |
Calcium channel blockers increase the amount of nitrite production in rabbits without decreasing the responsiveness of platelets to collagen.
Topics: Animals; Calcium Channel Blockers; Collagen; Diltiazem; Male; Nicardipine; Nitric Oxide; Nitrites; Oxidation-Reduction; Platelet Aggregation; Rabbits; Verapamil | 2007 |
[Suspected diltiazem intoxication resulting in repeated asystole after the induction of anesthesia].
Topics: Adult; Anesthesia; Diltiazem; Drug Interactions; Embolization, Therapeutic; Heart Arrest; Humans; Intracranial Aneurysm; Male; Midazolam; Nicardipine; Perioperative Care; Subarachnoid Hemorrhage | 2012 |
The effects of intravenous lipid emulsion on prolongation of survival in a rat model of calcium channel blocker toxicity.
Topics: Animals; Antidotes; Arterial Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Disease Models, Animal; Fat Emulsions, Intravenous; Heart Rate; Male; Nicardipine; Poisoning; Rats, Sprague-Dawley; Time Factors | 2015 |
An Assessment of the Oral Bioavailability of Three Ca-Channel Blockers Using a Cassette-Microdose Study: A New Strategy for Streamlining Oral Drug Development.
Topics: Administration, Intravenous; Administration, Oral; Adult; Biological Availability; Calcium Channel Blockers; Chromatography, Liquid; Diltiazem; Humans; Male; Mass Spectrometry; Nicardipine; Nifedipine; Young Adult | 2015 |
Evaluation of four calcium channel blockers as fluconazole resistance inhibitors in Candida glabrata.
Topics: Calcium Channel Blockers; Candida glabrata; Diltiazem; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Drug Synergism; Fluconazole; Microbial Sensitivity Tests; Microbial Viability; Nicardipine; Nifedipine; Verapamil | 2018 |