Page last updated: 2024-08-23

diltiazem and niacinamide

diltiazem has been researched along with niacinamide in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199016 (48.48)18.7374
1990's16 (48.48)18.2507
2000's0 (0.00)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Murao, S; Uchida, Y; Yoshimoto, N2
Baba, S; Fujii, S; Kazumi, T; Morita, S; Taniguchi, H; Yoshida, Y; Yoshino, G1
Krumenacker, M; Roland, E1
Asada, T; Higami, T; Kawamura, T; Mukohara, N; Nishiwaki, M; Ogawa, K; Okada, K; Sakata, M; Sugimoto, T1
Arakawa, K; Handa, K; Ikeda, K; Kawasaki, K; Saeki, Y; Sasaki, J; Umeno, M1
Satoh, K; Taira, N; Yamada, H; Yoneyama, F1
Imai, S; Ishibashi, T; Katsumata, N; Matsubara, T; Nakazawa, M1
Abiko, Y; Ichihara, K; Sakai, K1
Ishii, K; Sato, Y; Taira, N1
Ajioka, M; Fukushima, A; Hanaki, Y; Kondo, T; Ozawa, T; Sugiyama, S1
Hashimoto, K; Inoue, T; Kinoshita, M; Mitsunami, K; Ohbayashi, Y; Taguchi, H1
Fujimoto, M; Kitao, T; Kohara, H; Kumahara, Y; Morimoto, K; Ogihara, T; Ohde, H; Tai, H; Terada, K1
Geshi, E; Hiroshige, J; Katagiri, T; Konno, N; Mochizuki, M; Umetsu, K1
Fujiwara, M; Muramatsu, I1
Ogawa, N; Ono, H1
Araki, H; Hayata, N; Matsuguchi, T; Nakamura, M1
Ishii, K; Satoh, K; Taira, N; Yanagisawa, T1
Nakamura, Y; Sakai, K; Sugimoto, T; Yamazaki, T1
Nabata, H; Sakai, K1
Hirakawa, S; Ito, H1
Kinoshita, M; Nakae, I; Quan, L; Sugimoto, Y; Tsutamoto, T1
Fukushima, H; Harada, K; Izawa, T; Kaneta, S; Miwa, A; Ogawa, N1
Fukasawa, M; Fukui, K; Hirooka, S; Kohi, M; Orita, H; Uchino, H; Washio, M2
Blin, P; Guermonprez, JL; Peterlongo, F1
Fujiwara, R; Hayashi, T; Kutsumi, Y; Miyabo, S; Nakai, T; Oida, K; Tamai, T1
Araki, H; Higuchi, S; Kishi-Tanikawa, S; Takahashi, K; Takahashi, T; Tsuchida, K1
Araki, H; Higuchi, S; Masumiya, H; Noguchi, K; Sasaki, T; Shigenobu, K; Takahashi, K; Tanaka, H1
Aisaka, K; Hirata, Y1
Takahashi, K; Takahashi, T; Tanikawa, S1
Igata, Y; Ikeda, S; Maekawa, T; Shiraishi, M; Watanabe, T; Yamamoto, S1

Reviews

1 review(s) available for diltiazem and niacinamide

ArticleYear
Clinical profile of nicorandil: an overview of its hemodynamic properties and therapeutic efficacy.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 3

    Topics: Diltiazem; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents

1992

Trials

3 trial(s) available for diltiazem and niacinamide

ArticleYear
A multicenter comparison of nicorandil and diltiazem on serum lipid, apolipoprotein, and lipoprotein levels in patients with ischemic heart disease.
    Cardiovascular drugs and therapy, 1992, Volume: 6, Issue:5

    Topics: Aged; Apolipoproteins; Diltiazem; Female; Humans; Lipids; Lipoproteins; Male; Middle Aged; Myocardial Ischemia; Niacinamide; Nicorandil; Vasodilator Agents

1992
Comparison of antianginal activity of nicorandil, propranolol and diltiazem with reference to the antianginal mechanism.
    The American journal of cardiology, 1989, Jun-20, Volume: 63, Issue:21

    Topics: Adult; Angina Pectoris; Clinical Trials as Topic; Diltiazem; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Propranolol; Random Allocation; Vasodilator Agents

1989
A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.
    European heart journal, 1993, Volume: 14 Suppl B

    Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Infarction; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents

1993

Other Studies

29 other study(ies) available for diltiazem and niacinamide

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of anti-anginal agents on cyclical reductions of coronary blood flow.
    Japanese heart journal, 1978, Volume: 19, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Blood Pressure; Coronary Circulation; Diltiazem; Dipyridamole; Dogs; Electrocardiography; Injections, Intravenous; Niacinamide; Nicotinic Acids; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Periodicity; Phentolamine; Propranolol; Vasodilator Agents; Verapamil

1978
Effect of 2-nicotinamidethyl nitrate (SG 75) on coronary circulation.
    Japanese heart journal, 1978, Volume: 19, Issue:1

    Topics: Animals; Constriction, Pathologic; Coronary Circulation; Coronary Vessels; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Ligation; Niacinamide; Nifedipine; Nitrates; Nitroglycerin; Papaverine; Vasodilator Agents; Verapamil

1978
Effect of calcium antagonist on glucose-induced insulin and glucagon secretion in rats with insulin-secreting tumors induced by streptozotocin and nicotinamide.
    The Kobe journal of medical sciences, 1979, Volume: 25, Issue:2

    Topics: Adenoma, Islet Cell; Animals; Calcium; Diltiazem; Glucagon; Glucose; Glucose Tolerance Test; Insulin; Insulin Secretion; Male; Neoplasms, Experimental; Niacinamide; Pancreatic Neoplasms; Rats; Streptozocin

1979
[Efficacy of nicorandil on myocardial protection during coronary artery bypass grafting--a comparison with diltiazem].
    [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai, 1992, Volume: 40, Issue:8

    Topics: Cardioplegic Solutions; Coronary Artery Bypass; Diltiazem; Heart; Heart Rate; Humans; Middle Aged; Myocardium; Niacinamide; Nicorandil; Vasodilator Agents

1992
Specific but differential antagonism by glibenclamide of the vasodepressor effects of cromakalim and nicorandil in spinally-anaesthetized dogs.
    British journal of pharmacology, 1990, Volume: 100, Issue:3

    Topics: Anesthesia, Spinal; Animals; Benzopyrans; Blood Pressure; Calcium Channel Blockers; Cromakalim; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Glyburide; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Potassium Channels; Pyrroles

1990
On the mode of cardioprotection produced by a new bradycardic agent, FR 76830, during ischaemia and after reperfusion in the isolated perfused rat heart: a 31P-NMR study.
    Cardiovascular research, 1990, Volume: 24, Issue:12

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Diltiazem; Dose-Response Relationship, Drug; Heart Rate; Hydrogen-Ion Concentration; In Vitro Techniques; Ischemia; Magnetic Resonance Spectroscopy; Male; Morpholines; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Niacinamide; Rats; Rats, Inbred Strains; Time Factors

1990
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 8

    Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Propranolol; Sotalol; Vasodilator Agents

1987
Differential antagonism by Bay K 8644 of vasodilator effects of nifedipine, diltiazem, nicorandil and nitroglycerin in dog femoral circulation.
    British journal of pharmacology, 1988, Volume: 93, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Femoral Artery; Femur; Male; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Regional Blood Flow; Vasodilator Agents

1988
Acceleration of recovery of mitochondrial function after coronary reperfusion by various coronary dilating drugs in canine hearts.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Dilazep; Diltiazem; Dogs; Female; Heart Rate; Hemodynamics; In Vitro Techniques; Male; Mitochondria, Heart; Monoamine Oxidase Inhibitors; Niacinamide; Nicorandil; Reperfusion Injury; Vasodilator Agents

1989
Effects of the kallikrein-kinin system on phasic coronary vasospasm in dogs.
    Advances in experimental medicine and biology, 1989, Volume: 247B

    Topics: Animals; Bradykinin; Coronary Vasospasm; Coronary Vessels; Diltiazem; Dogs; Female; In Vitro Techniques; Kallikreins; Male; Niacinamide; Nicorandil; Nifedipine; Vasoconstriction; Vasodilator Agents

1989
Protection of acute ischemic myocardial injury by pharmacological intervention.
    Japanese circulation journal, 1989, Volume: 53, Issue:9

    Topics: Adenosine Triphosphatases; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium-Transporting ATPases; Coenzymes; Coronary Disease; Diltiazem; Dogs; Myocardium; Niacinamide; Nicorandil; Quinazolines; Sarcoplasmic Reticulum; Ubiquinone; Vasodilator Agents

1989
[Vasorelaxing action of nicorandil, in comparison with nitroglycerin and Ca antagonists].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1986, Volume: 87, Issue:2

    Topics: Animals; Aorta; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Drug Interactions; Male; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Prazosin; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil

1986
Different effects of various vasodilators on autoregulation of renal blood flow in anesthetized dogs.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:3

    Topics: Animals; Blood Pressure; Diltiazem; Dogs; Female; Homeostasis; Male; Niacinamide; Nicorandil; Nitroglycerin; Nitroprusside; Papaverine; Renal Circulation; Sodium Nitrite; Vasodilator Agents

1986
Effects of nicorandil on rest and effort angina unresponsive to combination therapy with a calcium antagonist and oral nitrate.
    Clinical therapeutics, 1987, Volume: 9, Issue:2

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Diltiazem; Drug Resistance; Drug Therapy, Combination; Female; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Physical Exertion; Prospective Studies; Rest; Vasodilator Agents

1987
Abolition of spontaneous rhythmic contractions of isolated monkey coronary arteries by diltiazem, nifedipine, verapamil and nicorandil but not by nitroglycerin.
    The Tohoku journal of experimental medicine, 1985, Volume: 145, Issue:1

    Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Erythrocebus patas; Female; In Vitro Techniques; Macaca mulatta; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Verapamil

1985
Protective effects of the antianginal agent nicorandil on arachidonate-induced sudden death in rats: comparison with several antianginal agents and cyclooxygenase inhibitors.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:1

    Topics: Angina Pectoris; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cyclooxygenase Inhibitors; Death, Sudden; Diltiazem; Indomethacin; Male; Mice; Niacinamide; Nicorandil; Nitroglycerin; Rats; Rats, Inbred Strains; Vasodilator Agents

1985
Effects of a new antianginal agent, nicorandil, on normoxic and anoxic contractions in isolated miniature pig coronary arteries exposed to 5-hydroxytryptamine and norepinephrine: comparison with nitroglycerin and diltiazem.
    European journal of pharmacology, 1983, Dec-09, Volume: 96, Issue:1-2

    Topics: Animals; Benzazepines; Coronary Vessels; Diltiazem; Drug Interactions; Female; Male; Muscle Contraction; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Oxygen; Serotonin Antagonists; Swine; Swine, Miniature

1983
Effects of vasodilators on the systemic capacitance vessels, a study with the measurement of the mean circulatory pressure in dogs.
    Japanese circulation journal, 1984, Volume: 48, Issue:4

    Topics: Animals; Blood Pressure; Blood Vessels; Blood Volume; Cardiac Output; Diltiazem; Dogs; Heart Rate; Isosorbide Dinitrate; Molsidomine; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Prazosin; Sydnones; Trapidil; Vascular Resistance; Vasodilator Agents; Venous Pressure; Verapamil

1984
Glibenclamide-induced oscillation of canine coronary artery is independent of myocardial ischemia.
    Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:3

    Topics: Adenosine Triphosphate; Animals; Arginine; Benzopyrans; Coronary Circulation; Coronary Vessels; Cromakalim; Diltiazem; Dogs; Female; Glyburide; In Vitro Techniques; Male; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Ischemia; Niacinamide; Nicorandil; Nitroarginine; Nitroglycerin; Potassium Channels; Pyrroles; Vasodilator Agents

1994
Effects of KRN2391, nicorandil and diltiazem on the changes in the electrocardiogram caused by endothelin-1 in anaesthetized rats.
    British journal of pharmacology, 1993, Volume: 109, Issue:3

    Topics: Action Potentials; Anesthesia; Animals; Blood Pressure; Cardiac Complexes, Premature; Diltiazem; Electrocardiography; Electrophysiology; Endothelins; Glyburide; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Methacholine Compounds; Niacinamide; Nicorandil; Pyridines; Rats; Rats, Wistar; Vasodilator Agents; Ventricular Fibrillation

1993
In vitro evaluation of nicorandil, diltiazem, and prostaglandin E1 on hypothermic injury to immature myocytes.
    The Journal of surgical research, 1995, Volume: 58, Issue:3

    Topics: Alprostadil; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cold Temperature; Creatine Kinase; Diltiazem; Female; Heart Rate; Heart Ventricles; L-Lactate Dehydrogenase; Myocardium; Niacinamide; Nicorandil; Rats; Rats, Wistar; Ventricular Function

1995
Cytoprotective effects of nicorandil on hypothermic injury to immature cardiac myocytes--comparison with nitroglycerin, diltiazem and prostaglandin E1.
    Japanese circulation journal, 1994, Volume: 58, Issue:8

    Topics: Alprostadil; Animals; Cells, Cultured; Cold Temperature; Creatine Kinase; Cryopreservation; Cryoprotective Agents; Diltiazem; Heart; L-Lactate Dehydrogenase; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Rats; Vasodilator Agents

1994
Effects of nicorandil on cell proliferation and cholesteryl ester accumulation in arterial smooth muscle cells in culture.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:3

    Topics: Animals; Aorta, Thoracic; Calcium Channels; Cell Division; Cells, Cultured; Cholesterol; Cholesterol Esters; Diltiazem; DNA; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Rats; Rats, Wistar; Vasodilator Agents; Verapamil

1993
Effects of a new calcium antagonist, CD-832, on isoproterenol-induced myocardial ischemia in dogs with partial coronary stenosis.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Dogs; Female; Heart Rate; Isoproterenol; Male; Myocardial Ischemia; Niacinamide; Nifedipine

1996
Relative selectivity for negative chronotropic and inotropic effects of a novel dihydropyridine derivative CD-832.
    European journal of pharmacology, 1996, Jul-11, Volume: 308, Issue:1

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Guinea Pigs; Heart Rate; Heart Ventricles; In Vitro Techniques; Male; Myocardial Contraction; Niacinamide; Nifedipine; Osmolar Concentration; Papillary Muscles; Patch-Clamp Techniques; Verapamil

1996
Effect of JTV-506, a novel vasodilator, on coronary blood flow in conscious dogs.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:3

    Topics: Administration, Oral; Animals; Benzopyrans; Blood Pressure; Chromans; Coronary Circulation; Cromakalim; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Male; Niacinamide; Nicorandil; Nitroglycerin; Pyrroles; Vasodilator Agents

1997
Protective effects of CD-832 on organ damage in stroke-prone spontaneously hypertensive rats.
    European journal of pharmacology, 1997, Jul-23, Volume: 331, Issue:2-3

    Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Diltiazem; Heart Rate; Hypertension; Kidney; Male; Myocardium; Niacinamide; Nifedipine; Organ Size; Rats; Rats, Inbred SHR; Rats, Inbred WKY

1997
Synthesis and biological activity of novel 2-(alpha-alkoxyimino)benzylpyridine derivatives as K+ channel openers.
    Chemical & pharmaceutical bulletin, 1997, Volume: 45, Issue:12

    Topics: Administration, Oral; Animals; Aorta, Thoracic; Blood Pressure; Coronary Circulation; Cromakalim; Cyclic N-Oxides; Diltiazem; Dogs; Hypertension; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Pyridines; Rats; Rats, Inbred SHR; Rats, Wistar; Structure-Activity Relationship; Vasodilation; Vasodilator Agents

1997