Page last updated: 2024-08-23

diltiazem and methylprednisolone

diltiazem has been researched along with methylprednisolone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's2 (9.09)18.2507
2000's10 (45.45)29.6817
2010's7 (31.82)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Neumayer, HH; Wagner, K1
Neumayer, HH; Schreiber, M; Wagner, K1
Baker, BA; Cacchione, JG1
D'Ambrosio, A; Quintieri, F; Segoloni, G1
Backman, JT; Kivistö, KT; Neuvonen, PJ; Varis, T1
Hashimoto, Y; Tashima, K; Uchino, M; Uyama, E; Yonehara, T1
Blum, RA; Booker, BM; Jusko, WJ; Lates, CD; Magee, MH1
Mehta, M1
Kurniawan, MZ; Lusida, M; Nugroho, J1

Reviews

1 review(s) available for diltiazem and methylprednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

4 trial(s) available for diltiazem and methylprednisolone

ArticleYear
Prevention of delayed graft function in cadaver kidney transplants by diltiazem: outcome of two prospective, randomized clinical trials.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Acute Kidney Injury; Adult; Cadaver; Clinical Trials as Topic; Cyclosporins; Diltiazem; Glomerular Filtration Rate; Graft Rejection; Humans; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Methylprednisolone; Prospective Studies; Random Allocation; Renal Circulation

1987
Prevention of delayed graft function by diltiazem and iloprost.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 2

    Topics: Clinical Trials as Topic; Cyclosporins; Diltiazem; Drug Therapy, Combination; Epoprostenol; Glomerular Filtration Rate; Humans; Iloprost; Kidney; Kidney Transplantation; Methylprednisolone; Prospective Studies; Random Allocation; Renal Circulation

1989
Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methylprednisolone.
    Clinical pharmacology and therapeutics, 2000, Volume: 67, Issue:3

    Topics: Adrenal Glands; Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Diltiazem; Double-Blind Method; Drug Synergism; Female; Humans; Hydrocortisone; Male; Methylprednisolone; Mibefradil; Reference Values

2000
Pharmacokinetic and pharmacodynamic interactions between diltiazem and methylprednisolone in healthy volunteers.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:4

    Topics: Adult; Area Under Curve; Diltiazem; Drug Interactions; Drug Therapy, Combination; Humans; Hydrocortisone; Least-Squares Analysis; Male; Methylprednisolone; Middle Aged; Statistics, Nonparametric; T-Lymphocytes

2002

Other Studies

17 other study(ies) available for diltiazem and methylprednisolone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Dermatologic cross-sensitivity between diltiazem and amlodipine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Amlodipine; Diltiazem; Diphenhydramine; Drug Eruptions; Humans; Hydroxyzine; Male; Methylprednisolone; Middle Aged; Pruritus

1994
The modulatory effect of diltiazem on human in vitro alloreactivity when used alone or in combination with cyclosporin A and/or methylprednisolone.
    Transplant international : official journal of the European Society for Organ Transplantation, 1997, Volume: 10, Issue:6

    Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents; Calcium Channel Blockers; Cell Survival; Cells, Cultured; Cyclosporine; Diltiazem; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Lymphocytes; Methylprednisolone

1997
Susac's syndrome: beneficial effects of corticosteroid therapy in a Japanese case.
    Internal medicine (Tokyo, Japan), 2001, Volume: 40, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Asian People; Asthma; Ataxia; Brain; Cognition Disorders; Confusion; Diagnosis, Differential; Diltiazem; Drug Therapy, Combination; Hearing Loss, Bilateral; Hearing Loss, Sensorineural; Humans; Magnetic Resonance Imaging; Male; Methylprednisolone; Multiple Sclerosis; Papilledema; Prednisone; Reflex, Abnormal; Retinal Artery; Retinal Artery Occlusion; Skin Diseases, Vascular; Syndrome; Ticlopidine; Vasculitis, Central Nervous System

2001
Drug incompatibility with methylprednisolone.
    Journal of neurosurgical anesthesiology, 2008, Volume: 20, Issue:3

    Topics: Adult; Anti-Inflammatory Agents; Antihypertensive Agents; Diltiazem; Drug Incompatibility; Hemangioma, Cavernous; Humans; Intraoperative Period; Male; Methylprednisolone; Spinal Cord Injuries; Spinal Cord Neoplasms

2008
Takayasu arteritis in a rural hospital in Indonesia.
    BMJ case reports, 2020, Jan-08, Volume: 13, Issue:1

    Topics: Adolescent; Angiography; Antihypertensive Agents; Cyclosporine; Diagnosis, Differential; Diltiazem; Drug Therapy, Combination; Electrocardiography; Female; Fever; Glucocorticoids; Hospitals, Rural; Humans; Immunosuppressive Agents; Indonesia; Methylprednisolone; Takayasu Arteritis

2020