diltiazem has been researched along with methyldopa in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (20.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 8 (40.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ram, CV | 1 |
| Macaulay, RM; Pearl, RM; Waters, LM | 1 |
| Cerný, J; Dostál, M; Gregor, Z; Guba, P; Rebícek, J; Sotolová, O; Urbánek, P; Vasků, A; Vasků, J | 1 |
| Henderson, S; Massie, BM; Parmley, WW; Sievers, R; Szlachcic, J; Tubau, JF; Wikman-Coffelt, J | 1 |
| Bernheim, J; Green, J; Haskiah, A; Podjarny, E; Pomeranz, A; Rathaus, M | 1 |
| Benchetrit, S; Bernheim, J; Green, J; Katz, B; Podjarny, E | 1 |
| Modirrousta, M; Tachere, RO | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
| Imani, R; Shabani-Nooshabadi, M; Ziaie, N | 1 |
2 review(s) available for diltiazem and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Calcium antagonists in the treatment of hypertension.
Topics: Biological Transport, Active; Calcium; Calcium Channel Blockers; Captopril; Diltiazem; Diuretics; Drug Resistance; Drug Therapy, Combination; Electrophysiology; Humans; Hypertension; Hypertension, Renovascular; Ion Channels; Kinetics; Methyldopa; Muscle, Smooth, Vascular; Nifedipine; Propranolol; Sodium; Vascular Resistance; Verapamil | 1985 |
18 other study(ies) available for diltiazem and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A comparative analysis of the ability of five classes of pharmacological agents to augment skin flap survival in various models and species: an attempt to standardize skin flap research.
Topics: Animals; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation, Preclinical; Graft Survival; Isoxsuprine; Macaca nemestrina; Male; Methyldopa; Nitroglycerin; Prazosin; Rats; Surgical Flaps | 1989 |
[Therapy of venous hypertension in animals with an artificial heart and long-term survival].
Topics: Animals; Antihypertensive Agents; Captopril; Cattle; Clonidine; Diltiazem; Heart, Artificial; Methyldopa; Nifedipine; Prazosin; Venous Pressure | 1989 |
Diltiazem prevents hypertrophy progression, preserves systolic function, and normalises myocardial oxygen utilisation in the spontaneously hypertensive rat.
Topics: Animals; Cardiomegaly; Coronary Circulation; Diltiazem; Heart; Hypertension; In Vitro Techniques; Methyldopa; Myocardium; Myosins; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Systole | 1987 |
Effect of diltiazem and methyldopa on gestation-related renal complications in rats with adriamycin nephrosis. Relationship to glomerular prostanoid synthesis.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diltiazem; Doxorubicin; Female; Hypertension; Kidney Diseases; Kidney Glomerulus; Methyldopa; Pregnancy; Pregnancy Complications; Prostaglandins; Proteinuria; Rats; Rats, Wistar | 1995 |
Effect of methyldopa on renal function in rats with L-NAME-induced hypertension in pregnancy.
Topics: Animals; Arginine; Diltiazem; Drinking; Eating; Female; Hypertension; Kidney; Methyldopa; NG-Nitroarginine Methyl Ester; Nitrates; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar | 2001 |
Beyond anxiety and agitation: A clinical approach to akathisia.
Topics: Adult; Antidepressive Agents; Antiemetics; Antipsychotic Agents; Anxiety; Buspirone; Cinnarizine; Diltiazem; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Methyldopa; Psychomotor Agitation; Reserpine; Suicidal Ideation | 2017 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |
Fabrication of a sensitive sensor for electrochemical detection of diltiazem in presence of methyldopa.
Topics: Diltiazem; Electrochemical Techniques; Electrodes; Graphite; Humans; Methyldopa; Nanocomposites | 2022 |