Page last updated: 2024-08-23

diltiazem and methylcellulose

diltiazem has been researched along with methylcellulose in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.00)18.2507
2000's27 (67.50)29.6817
2010's9 (22.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fassihi, R; Kim, H2
Buaria, CP; Chhabaria, MT; Gohel, MC; Patel, MM1
Cheng, K; Song, X; Sun, L; Zhang, J; Zhu, J1
Bruni, R; Conte, U; Maggi, L1
Fassihi, R; Pillay, V1
Peh, KK; Wong, CF1
Attwood, D; Hou, WM; Iwatsu, M; Kawasaki, N; Miyazaki, S; Nakamura, T1
Fukui, E; Kobayashi, M; Miyamura, N2
Fukui, E; Kobayashi, M; Miyamura, N; Yoneyama, T1
Gohel, MC; Sumitra G, M1
Chatlapalli, R; Rohera, BD1
Ahuja, N; Singh, B1
Buttafava, A; Conte, U; Faucitano, A; Maggi, L; Ochoa Machiste, E; Segale, L1
Albini, A; Conte, U; Fasani, E; Maggi, L; Ochoa Machiste, E; Segale, L1
Zhang, N; Zhu, JB1
Liang, WQ; Wei, XH; Wu, JJ1
Kanaujia, P; Prabakaran, D; Singh, P; Vyas, SP1
Medvecká, G; Rabisková, M; Vostalová, L1
Jaganathan, KS; Kanaujia, P; Mishra, V; Prabakaran, D; Singh, P; Vyas, SP1
Kosmidis, K; Macheras, P; Papadopoulou, V; Vlachou, M1
Khan, NA; Wong, JW; Yuen, KH1
Conte, U; Conti, S; Grenier, P; Maggi, L; Ochoa Machiste, E; Segale, L; Vergnault, G2
Buckton, G; Conte, U; Conti, S; Gaisford, S; Maggi, L1
Chen, S; Cheng, J; Zhu, J1
Limpongsa, E; Umprayn, K1
Alexander, KS; Fifer, EK; Kim, CJ; Vadlapatla, R1
Boyapally, H; Douroumis, D; Nukala, RK1
Fassihi, R; Liu, Q1
Kikuchi, S; Takayama, K1
Dedhiya, M; Karakatsani, M; Plakogiannis, FM1
Hayashi, Y; Kikuchi, S; Onuki, Y; Takayama, K; Yasuda, A1
Han, HK; Lee, HK1
Bresolin, JR; Dalri, CC; Hoffer, G; Largura, MC; Lucinda-Silva, RM; Rodrigues, CA1
Hasan, SM; Mehmood, ZA; Qazi, F; Qazi, TM; Shoaib, MH; Yousuf, RI1
Adibkia, K; Barzegar-Jalali, M; Ghanbarzadeh, S; Khiavi, HZ; Mohammadi, G; Sabzevari, A1
Choonara, YE; du Toit, LC; Khan, Z; Kumar, P; Ndesendo, VM; Pillay, V1
Bratoeva, KZ; Corbo, F; Franchini, C; Franco, CD; Ivanova, NA; Kolev, IN; Mandracchia, D; Stoyanov, GS; Trapani, A; Trapani, G; Tripodo, G1

Other Studies

40 other study(ies) available for diltiazem and methylcellulose

ArticleYear
Application of binary polymer system in drug release rate modulation. 2. Influence of formulation variables and hydrodynamic conditions on release kinetics.
    Journal of pharmaceutical sciences, 1997, Volume: 86, Issue:3

    Topics: Delayed-Action Preparations; Diltiazem; Kinetics; Lactose; Methylcellulose; Molecular Weight; Nifedipine; Oxazines; Pectins; Prednisolone; Pressure; Solubility; Tablets; Theophylline

1997
A new ternary polymeric matrix system for controlled drug delivery of highly soluble drugs: I. Diltiazem hydrochloride.
    Pharmaceutical research, 1997, Volume: 14, Issue:10

    Topics: Delayed-Action Preparations; Diltiazem; Drug Delivery Systems; Gelatin; Hypromellose Derivatives; Kinetics; Methylcellulose; Pectins; Solubility; Tablets

1997
Preliminary investigations in matrix-based tablet formulations of diltiazem hydrochloride containing succinic acid-treated methylcellulose.
    Pharmaceutical development and technology, 1998, Volume: 3, Issue:4

    Topics: Calcium Channel Blockers; Diltiazem; Methylcellulose; Solubility; Succinic Acid; Tablets

1998
Studies of hydroxypropyl methylcellulose donut-shaped tablets.
    Drug development and industrial pharmacy, 1999, Volume: 25, Issue:9

    Topics: Diltiazem; Lactose; Methylcellulose; Oxazines; Solubility; Tablets; Theophylline; Time Factors

1999
High molecular weight polyethylene oxides (PEOs) as an alternative to HPMC in controlled release dosage forms.
    International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2

    Topics: Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Excipients; Lactose; Methylcellulose; Molecular Weight; Oxazines; Polyethylene Glycols; Tablets

2000
In situ electrolyte interactions in a disk-compressed configuration system for up-curving and constant drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2000, Jun-15, Volume: 67, Issue:1

    Topics: Diltiazem; Drug Delivery Systems; Electrolytes; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Methylcellulose; Molecular Weight; Polyethylene Glycols; Solubility; Tablets, Enteric-Coated; Theophylline

2000
Application of similarity factor in development of controlled-release diltiazem tablet.
    Drug development and industrial pharmacy, 2000, Volume: 26, Issue:7

    Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Carriers; Hydrogen-Ion Concentration; Lactose; Methylcellulose; Oxazines; Polysaccharides, Bacterial; Tablets

2000
Oral mucosal bioadhesive tablets of pectin and HPMC: in vitro and in vivo evaluation.
    International journal of pharmaceutics, 2000, Aug-25, Volume: 204, Issue:1-2

    Topics: Adhesives; Animals; Antihypertensive Agents; Delayed-Action Preparations; Diltiazem; Food Additives; Lactose; Male; Methylcellulose; Mouth Mucosa; Oxazines; Pectins; Rabbits; Rats; Tablets

2000
An in vitro investigation of the suitability of press-coated tablets with hydroxypropylmethylcellulose acetate succinate (HPMCAS) and hydrophobic additives in the outer shell for colon targeting.
    Journal of controlled release : official journal of the Controlled Release Society, 2001, Jan-29, Volume: 70, Issue:1-2

    Topics: Colon; Diltiazem; Hydrogen-Ion Concentration; Methylcellulose; Pressure; Solubility; Tablets

2001
Effect of magnesium stearate or calcium stearate as additives on dissolution profiles of diltiazem hydrochloride from press-coated tablets with hydroxypropylmethylcellulose acetate succinate in the outer shell.
    International journal of pharmaceutics, 2001, Mar-23, Volume: 216, Issue:1-2

    Topics: Antihypertensive Agents; Chemistry, Pharmaceutical; Diltiazem; Excipients; Methylcellulose; Porosity; Stearic Acids; Tablets

2001
Drug release from and mechanical properties of press-coated tablets with hydroxypropylmethylcellulose acetate succinate and plasticizers in the outer shell.
    International journal of pharmaceutics, 2001, Apr-17, Volume: 217, Issue:1-2

    Topics: Cardiovascular Agents; Compressive Strength; Diltiazem; Mechanics; Methylcellulose; Plasticizers; Solubility; Tablets, Enteric-Coated

2001
Modulation of active pharmaceutical material release from a novel 'tablet in capsule system' containing an effervescent blend.
    Journal of controlled release : official journal of the Controlled Release Society, 2002, Feb-19, Volume: 79, Issue:1-3

    Topics: Capsules; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Delivery Systems; Galactans; Lactose; Mannans; Methylcellulose; Oxazines; Plant Gums; Powders; Tablets

2002
Study of effect of excipient source variation on rheological behavior of diltiazem HCl-HPMC wet masses using a mixer torque rheometer.
    International journal of pharmaceutics, 2002, May-15, Volume: 238, Issue:1-2

    Topics: Calorimetry, Differential Scanning; Chemical Phenomena; Chemistry, Physical; Diltiazem; Drug Compounding; Excipients; Hypromellose Derivatives; Methylcellulose; Microscopy, Electron, Scanning; Particle Size; Powders; Rheology; Solubility; Spectrophotometry, Infrared; X-Ray Diffraction

2002
Development of controlled-release buccoadhesive hydrophilic matrices of diltiazem hydrochloride: optimization of bioadhesion, dissolution, and diffusion parameters.
    Drug development and industrial pharmacy, 2002, Volume: 28, Issue:4

    Topics: Acrylates; Administration, Buccal; Analysis of Variance; Animals; Antihypertensive Agents; Delayed-Action Preparations; Diffusion; Diltiazem; Excipients; Hypromellose Derivatives; In Vitro Techniques; Kinetics; Methylcellulose; Models, Chemical; Mouth Mucosa; Solubility; Swine; Tablets; Technology, Pharmaceutical; Tissue Adhesions

2002
Chemical and physical stability of hydroxypropylmethylcellulose matrices containing diltiazem hydrochloride after gamma irradiation.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:1

    Topics: Chemistry, Pharmaceutical; Diltiazem; Gamma Rays; Hypromellose Derivatives; Methylcellulose; Tablets

2003
Photostability of extended-release matrix formulations.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2003, Volume: 55, Issue:1

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Stability; Excipients; Hypromellose Derivatives; Methylcellulose; Nifedipine; Polyethylene Glycols; Solubility; Tablets; Time Factors; Ultraviolet Rays

2003
[Preparation of diltiazem hydrochloride delayed-onset, sustained release tablet].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:9

    Topics: Cellulose; Delayed-Action Preparations; Diltiazem; Lactose; Methylcellulose; Oxazines; Polyvinyls; Pyrrolidinones; Tablets; Technology, Pharmaceutical; Viscosity

2002
[Application of an artificial neural network in the design of sustained-release dosage forms].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2001, Volume: 36, Issue:9

    Topics: Delayed-Action Preparations; Dextrans; Diltiazem; Drug Design; Isoniazid; Lactose; Methylcellulose; Neural Networks, Computer; Oxazines; Ranitidine; Solubility; Tablets

2001
Effect of hydrophilic polymers on the release of diltiazem hydrochloride from elementary osmotic pumps.
    International journal of pharmaceutics, 2003, Jun-18, Volume: 259, Issue:1-2

    Topics: Calcium Channel Blockers; Carboxymethylcellulose Sodium; Cellulose; Delayed-Action Preparations; Diltiazem; Drug Carriers; Excipients; Hypromellose Derivatives; Kinetics; Methylcellulose; Osmosis; Solubility; Technology, Pharmaceutical

2003
[Release of diltiazem chloride and ibuprofen from hydrophilic matrix tablets].
    Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2003, Volume: 52, Issue:6

    Topics: Cardiovascular Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Ibuprofen; Lactose; Methylcellulose; Oxazines; Solubility; Tablets

2003
Controlled porosity osmotic pumps of highly aqueous soluble drug containing hydrophilic polymers as release retardants.
    Pharmaceutical development and technology, 2004, Volume: 9, Issue:4

    Topics: Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Data Interpretation, Statistical; Delayed-Action Preparations; Diltiazem; Drug Carriers; Drug Stability; Hypromellose Derivatives; Methylcellulose; Osmosis; Pharmaceutical Preparations; Polymers; Porosity; Solubility; Water

2004
On the use of the Weibull function for the discernment of drug release mechanisms.
    International journal of pharmaceutics, 2006, Feb-17, Volume: 309, Issue:1-2

    Topics: Delayed-Action Preparations; Diclofenac; Diffusion; Diltiazem; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Polymers; Solubility; Tablets

2006
Drug-polymer mixed coating: a new approach for controlling drug release rates in pellets.
    Pharmaceutical development and technology, 2006, Volume: 11, Issue:1

    Topics: Algorithms; Data Interpretation, Statistical; Delayed-Action Preparations; Diltiazem; Drug Compounding; Drug Storage; Excipients; Hydrogen-Ion Concentration; Hypromellose Derivatives; Methylcellulose; Microscopy, Electron, Scanning; Pharmaceutical Preparations; Polymers; Solubility

2006
Matrices containing NaCMC and HPMC 1. Dissolution performance characterization.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diffusion; Diltiazem; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Solubility; Tablets; Technology, Pharmaceutical

2007
Matrices containing NaCMC and HPMC 2. Swelling and release mechanism study.
    International journal of pharmaceutics, 2007, Mar-21, Volume: 333, Issue:1-2

    Topics: Buffers; Carboxymethylcellulose Sodium; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Methylcellulose; Molecular Structure; Solubility; Tablets; Technology, Pharmaceutical; Water

2007
The role of solution calorimetry in investigating controlled-release processes from polymeric drug delivery systems.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 68, Issue:3

    Topics: Calorimetry; Carboxymethylcellulose Sodium; Delayed-Action Preparations; Diltiazem; Hypromellose Derivatives; Methylcellulose; Polymers; Solubility; Solutions; Tablets

2008
Preparation and in vitro evaluation of a novel combined multiparticulate delayed-onset sustained-release formulation of diltiazem hydrochloride.
    Die Pharmazie, 2007, Volume: 62, Issue:12

    Topics: Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Compounding; Excipients; Hydrogen-Ion Concentration; Hypromellose Derivatives; Kinetics; Linear Models; Methylcellulose; Microscopy, Electron, Scanning; Microspheres; Models, Chemical; Osmotic Pressure; Particle Size; Polysorbates; Solubility

2007
Preparation and evaluation of diltiazem hydrochloride diffusion-controlled transdermal delivery system.
    AAPS PharmSciTech, 2008, Volume: 9, Issue:2

    Topics: Administration, Cutaneous; Animals; Calcium Channel Blockers; Cellulose; Chemistry, Pharmaceutical; Citrates; Delayed-Action Preparations; Dibutyl Phthalate; Diffusion; Diffusion Chambers, Culture; Diltiazem; Dosage Forms; Drug Carriers; Drug Compounding; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Myristates; Palmitates; Permeability; Plasticizers; Polysorbates; Skin; Skin Absorption; Solubility; Swine; Technology, Pharmaceutical; Tensile Strength; Water

2008
Drug-organic electrolyte complexes as controlled release systems.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:1

    Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Deoxycholic Acid; Diltiazem; Drug Carriers; Electrolytes; Ethylenediamines; Hydrogen-Ion Concentration; Hypromellose Derivatives; Magnetic Resonance Spectroscopy; Methylcellulose; Solubility; Spectroscopy, Fourier Transform Infrared; Tablets; Time Factors; Viscosity

2009
Development and release mechanism of diltiazem HCl prolonged release matrix tablets.
    Drug delivery, 2009, Volume: 16, Issue:2

    Topics: Acrylic Resins; Biological Availability; Cellulose; Delayed-Action Preparations; Diltiazem; Drug Stability; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Kinetics; Lactose; Methacrylates; Methylcellulose; Microscopy, Electron, Scanning; Models, Chemical; Polymers; Tablets

2009
Application of a novel symmetrical shape factor to gastroretentive matrices as a measure of swelling synchronization and its impact on drug release kinetics under standard and modified dissolution conditions.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:7

    Topics: Delayed-Action Preparations; Diltiazem; Drug Carriers; Excipients; Hypromellose Derivatives; Kinetics; Methylcellulose; Polyethylene Glycols; Povidone; Quinazolines; Solubility; Tablets; Technology, Pharmaceutical; Theophylline

2009
Multivariate statistical approach to optimizing sustained-release tablet formulations containing diltiazem hydrochloride as a model highly water-soluble drug.
    International journal of pharmaceutics, 2010, Feb-15, Volume: 386, Issue:1-2

    Topics: Chemistry, Pharmaceutical; DEAE-Dextran; Delayed-Action Preparations; Dextran Sulfate; Diltiazem; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Models, Statistical; Multivariate Analysis; Nonlinear Dynamics; Reproducibility of Results; Solubility; Tablets; Technology, Pharmaceutical; Water

2010
The effect of permeation enhancers on the viscosity and the release profile of transdermal hydroxypropyl methylcellulose gel formulations containing diltiazem HCl.
    Drug development and industrial pharmacy, 2010, Volume: 36, Issue:10

    Topics: Administration, Cutaneous; Calcium Channel Blockers; Chemistry, Pharmaceutical; Diltiazem; Drug Carriers; Drug Delivery Systems; Excipients; Fatty Acids; Gels; Humans; Hypromellose Derivatives; Methylcellulose; Permeability; Skin; Skin Absorption; Solubility; Technology, Pharmaceutical; Viscosity

2010
Latent structure analysis in pharmaceutical formulations using Kohonen's self-organizing map and a Bayesian network.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:3

    Topics: Algorithms; Bayes Theorem; Calcium Channel Blockers; Cluster Analysis; Dextran Sulfate; Diltiazem; Dosage Forms; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Methylcellulose; Models, Statistical; Pharmaceutical Preparations; Polymers; Solubility; Tablets; Viscosity

2011
Improved effectiveness of biochanin A as a P-gp inhibitor in solid dispersion.
    Die Pharmazie, 2011, Volume: 66, Issue:9

    Topics: Administration, Oral; Animals; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Calcium Channel Blockers; Cell Line; Cell Line, Tumor; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Diltiazem; Drug Carriers; Genistein; Humans; Hypromellose Derivatives; Injections, Intravenous; Male; Methylcellulose; Rats; Rats, Sprague-Dawley; Solubility

2011
Spray-dried O-carboxymethyl chitosan as potential hydrophilic matrix tablet for sustained release of drug.
    Drug development and industrial pharmacy, 2014, Volume: 40, Issue:4

    Topics: Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Diltiazem; Excipients; Hydrophobic and Hydrophilic Interactions; Hypromellose Derivatives; Methylcellulose; Surface Properties; Tablets

2014
Formulation development and evaluation of Diltiazem HCl sustained release matrix tablets using HPMC K4M and K100M.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:4

    Topics: Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Hypromellose Derivatives; Methylcellulose; Solubility; Tablets

2013
Drug release kinetic analysis and prediction of release data via polymer molecular weight in sustained release diltiazem matrices.
    Drug research, 2014, Volume: 64, Issue:3

    Topics: Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Diltiazem; Excipients; Hypromellose Derivatives; Kinetics; Methylcellulose; Models, Chemical; Molecular Weight; Polymers; Solubility; Tablets; Time Factors; Tragacanth

2014
A novel multilayered multidisk oral tablet for chronotherapeutic drug delivery.
    BioMed research international, 2013, Volume: 2013

    Topics: Cellulose; Diltiazem; Drug Chronotherapy; Drug Delivery Systems; Ethylene Glycols; Humans; Hypromellose Derivatives; Kinetics; Methylcellulose; Pectins; Polymers; Tablets

2013
In vitro and ex vivo studies on diltiazem hydrochloride-loaded microsponges in rectal gels for chronic anal fissures treatment.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: Acrylic Resins; Administration, Rectal; Animals; Chronic Disease; Diltiazem; Drug Delivery Systems; Drug Liberation; Fissure in Ano; Gels; Methylcellulose; Mucous Membrane; Poloxamer; Swine

2019