Page last updated: 2024-08-23

diltiazem and lisinopril

diltiazem has been researched along with lisinopril in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (53.57)18.2507
2000's6 (21.43)29.6817
2010's7 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bakris, GL1
Collins, TJ; Mehra, MR; Ramee, SR; Smart, FW; Stapleton, DD; Ventura, HO1
Amery, A; Bulpitt, CJ; Coope, J; Evans, JG; Fletcher, AE; Lightowlers, S; O'Malley, K; Palmer, A; Potter, J; Sever, P1
Anzalone, D; Chrysant, S; Fagan, T; Flamenbaum, W; Kaihlanen, PM; Lueg, M; Weir, MR1
Bakris, G; Brown, S; Gaber, L; Walton, C1
Jue, S; Mason, B; Matsuyama, J1
Hamer, HP; Havinga, TK; Lie, KI; May, JF; Schuurman, FH; Smit, AJ; ten Berge, BS; van der Veur, E; van Leeuwen, JT; Wesseling, H1
Amado, P; Araújo, V; Carmona, J; Castanheira, J; Nazaré, J1
Bakris, GL; Sadler, R; Slataper, R; Vicknair, N1
Bakris, GL; Brown, SA; Crawford, P; Walton, CL1
Lund-Johansen, P; Omvik, P1
Hamer, HP; Havinga, TK; Lie, KI; May, JF; Schuurman, FH; Smit, AJ; ten Berge, BS; van der Veru, E; van Leeuwen, JT; Wesseling, H1
Brandão, F; Faria, DB; Gomes, MC; Macedo, F; Martins, L; Polónia, J; Simões, L1
Bourge, R; Brozena, SC; Clemson, B; Hobbs, R; Johnson, MR; Miller, L; Mills, RM; Naftel, D; Olivari, MT; Quigg, R; Ventura, H1
Chan, P; Lee, YS; Lin, CN; Lin, TH; Tomlinson, B1
Handler, J1
Karotsis, AK; Mastorantonakis, SE; Stergiou, GS; Symeonidis, A1
Carroll, C; Hassanin, A1

Reviews

2 review(s) available for diltiazem and lisinopril

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
    Drugs & aging, 1994, Volume: 5, Issue:3

    Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Studies; Humans; Hypertension; Lisinopril; Longitudinal Studies; Research Design; Survival Rate

1994

Trials

10 trial(s) available for diltiazem and lisinopril

ArticleYear
Effects of diltiazem or lisinopril on massive proteinuria associated with diabetes mellitus.
    Annals of internal medicine, 1990, May-01, Volume: 112, Issue:9

    Topics: Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Diabetes Complications; Diltiazem; Enalapril; Female; Humans; Lisinopril; Male; Middle Aged; Prospective Studies; Proteinuria

1990
The Hypertension in the Very Elderly Trial (HYVET). Rationale, methodology and comparison with previous trials.
    Drugs & aging, 1994, Volume: 5, Issue:3

    Topics: Aged; Aged, 80 and over; Bendroflumethiazide; Delayed-Action Preparations; Diltiazem; Follow-Up Studies; Humans; Hypertension; Lisinopril; Longitudinal Studies; Research Design; Survival Rate

1994
Comparison of the efficacy and tolerability of an angiotensin converting enzyme inhibitor (lisinopril) versus a calcium channel antagonist (diltiazem SR) in the treatment of moderate to severe hypertension.
    Journal of human hypertension, 1994, Volume: 8, Issue:7

    Topics: Blood Pressure; Diltiazem; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged

1994
Comparative study of diltiazem and lisinopril in hypertension: similar improvements in diastolic function despite different effects on left ventricular mass and ambulatory blood pressure.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Blood Pressure; Diastole; Diltiazem; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Middle Aged; Ultrasonography

1993
Comparative effects of different antihypertensive treatments on progression of diabetic renal disease.
    Archives of internal medicine, 1993, Apr-26, Volume: 153, Issue:8

    Topics: Albuminuria; Antihypertensive Agents; Atenolol; Diabetic Nephropathies; Diltiazem; Dipeptides; Furosemide; Glomerular Filtration Rate; Hemodynamics; Humans; Lisinopril; Middle Aged; Prospective Studies; Renal Circulation

1993
Comparative effects of diltiazem and lisinopril on left ventricular structure and filling in mild-to-moderate hypertension.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:6

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Ventricular Function, Left

1995
Lisinopril and diltiazem reduce left ventricular mass without changing blood pressure in normotensive subjects with exaggerated blood pressure response to exercise.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1996, Volume: 15, Issue:3

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Diltiazem; Echocardiography; Exercise; Humans; Hypertrophy, Left Ventricular; Lisinopril; Male; Middle Aged; Single-Blind Method

1996
Effectiveness and safety of diltiazem or lisinopril in treatment of hypertension after heart transplantation. Results of a prospective, randomized multicenter trail.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:7

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Diltiazem; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Lisinopril; Male; Middle Aged; Postoperative Complications; Prospective Studies; Treatment Outcome

1996
Additive effects of diltiazem and lisinopril in the treatment of elderly patients with mild-to-moderate hypertension.
    American journal of hypertension, 1997, Volume: 10, Issue:7 Pt 1

    Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Patient Compliance; Quality of Life

1997
Additional antihypertensive effect of drugs in hypertensive subjects uncontrolled on diltiazem monotherapy: a randomized controlled trial using office and home blood pressure monitoring.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2006, Volume: 28, Issue:7

    Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Diltiazem; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Office Visits; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2006

Other Studies

17 other study(ies) available for diltiazem and lisinopril

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy.
    The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Coronary Disease; Diltiazem; Enalapril; Female; Heart Transplantation; Humans; Hyperplasia; Lisinopril; Male; Middle Aged; Nifedipine; Transplantation, Homologous; Tunica Intima; Ultrasonography, Interventional; Verapamil

1995
Effects of different antihypertensive treatments on morphologic progression of diabetic nephropathy in uninephrectomized dogs.
    Kidney international, 1994, Volume: 46, Issue:1

    Topics: Animals; Antihypertensive Agents; Diabetic Nephropathies; Diltiazem; Dogs; Drug Therapy, Combination; Fibrosis; Glomerular Mesangium; Glomerulosclerosis, Focal Segmental; Lisinopril; Nephrectomy; Nephritis, Interstitial

1994
Adherence consistency across treatment regimens.
    Diabetes care, 1994, Volume: 17, Issue:4

    Topics: Aged; Clinical Trials as Topic; Coronary Disease; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Diltiazem; Humans; Hypoglycemic Agents; Isosorbide; Joint Diseases; Lisinopril; Male; Treatment Refusal

1994
[Paroxysmal atrial fibrillation and flutter and "occult" arterial hypertension. The importance of the ambulatory monitoring of the blood pressure. Apropos 2 cases].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1993, Volume: 12, Issue:10

    Topics: Atenolol; Atrial Fibrillation; Atrial Flutter; Blood Pressure Monitors; Diltiazem; Drug Therapy, Combination; Humans; Hypertension; Lisinopril; Male; Middle Aged; Verapamil

1993
Long-term effects of antihypertensive regimens on renal hemodynamics and proteinuria.
    Kidney international, 1993, Volume: 43, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Dipeptides; Dogs; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Hemodynamics; Homeostasis; Kidney; Lisinopril; Male; Proteinuria; Renal Circulation

1993
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil

2005
Polypharmacy in the Elderly-When Good Drugs Lead to Bad Outcomes: A Teachable Moment.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Aged, 80 and over; Anti-Arrhythmia Agents; Antihypertensive Agents; Atorvastatin; Atrial Fibrillation; Bone Density Conservation Agents; Deprescriptions; Digoxin; Diltiazem; Diuretics; Drug Overdose; Factor Xa Inhibitors; Female; Furosemide; Heart Failure; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ibandronic Acid; Lisinopril; Loratadine; Metoprolol; Polypharmacy; Pyrazoles; Pyridones; Ranitidine; Syncope

2017