Page last updated: 2024-08-23

diltiazem and labetalol

diltiazem has been researched along with labetalol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's2 (7.69)18.2507
2000's7 (26.92)29.6817
2010's10 (38.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Akamatsu, M1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Danis, M; Dukes, GE; Hak, LJ; Han, YH; Hermann, DJ; Hussey, EK; Krol, TF; Powell, JR1
Fruncillo, RA; Lener, ME; Rocci, ML; Sirgo, MA; Vlasses, PH1
Feldman, RL; Hill, JA; Lambert, CR; Prida, XE1
Cubeddu, LX; Halperin, AK1
Casthely, PA; Fyman, PN; Gandhi, P; Litwak, B; Rabinowitz, L; Villanueva, R1
Lowenthal, DT1
Chiang, BN; Hong, CY1
Lund-Johansen, P; Omvik, P1
Luo, K; Wang, Y; Wu, T; Yang, J; You, X1
Caneer, PM; Hoskins, MH; Khan, BV; Leleiko, RM; Ramos, JJ; Sola, S1
Punkla, W; Raksamani, K; Rushatamukayanunt, P; Sakaew, A; Sirivanasandha, B; Sutthivaiyakit, K; Waitayawinyu, P1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM1

Reviews

2 review(s) available for diltiazem and labetalol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The role of calcium channel blockers in the treatment of hypertension.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil

1986

Trials

5 trial(s) available for diltiazem and labetalol

ArticleYear
Comparison of verapamil, diltiazem, and labetalol on the bioavailability and metabolism of imipramine.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Antidepressive Agents, Tricyclic; Biological Availability; Desipramine; Diltiazem; Drug Administration Schedule; Drug Interactions; Humans; Imipramine; Labetalol; Male; Verapamil

1992
Comparative evaluation of the effects of labetalol, verapamil and diltiazem on antipyrine and indocyanine green clearances.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:10

    Topics: Adult; Antipyrine; Diltiazem; Half-Life; Humans; Indocyanine Green; Labetalol; Male; Random Allocation; Verapamil

1989
The role of calcium channel blockers in the treatment of hypertension.
    American heart journal, 1986, Volume: 111, Issue:2

    Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Follow-Up Studies; Heart Rate; Hemodynamics; Humans; Hypertension; Kidney; Kinetics; Labetalol; Nifedipine; Sympathetic Nervous System; Verapamil

1986
[The clinical application of compound induced hypotension during functional endoscopic sinus surgery].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2006, Volume: 20, Issue:24

    Topics: Adult; Aged; Antihypertensive Agents; Diltiazem; Endoscopy; Female; Humans; Hypotension, Controlled; Labetalol; Male; Middle Aged; Nasal Polyps; Nitroprusside; Paranasal Sinuses; Sinusitis

2006
An Equivalence Trial Comparing Labetalol and Diltiazem in Controlling Emergence Hypertension after Supratentorial Tumor Surgery.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2015, Volume: 98, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Diltiazem; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Supratentorial Neoplasms; Thailand; Young Adult

2015

Other Studies

20 other study(ies) available for diltiazem and labetalol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Systemic and coronary hemodynamics of labetalol in normotensive patients with ischemic heart disease.
    Cardiovascular drugs and therapy, 1988, Volume: 2, Issue:3

    Topics: Coronary Circulation; Coronary Disease; Diltiazem; Hemodynamics; Humans; Labetalol; Nicardipine

1988
Intrapulmonary shunting during deliberate hypotension with nifedipine, diltiazem and labetalol in dogs.
    Canadian Anaesthetists' Society journal, 1985, Volume: 32, Issue:2

    Topics: Anesthesia; Animals; Benzazepines; Blood Pressure; Diltiazem; Dogs; Ethanolamines; Heart Rate; Hypotension, Controlled; Labetalol; Nifedipine; Pulmonary Circulation

1985
New drugs for hypertension.
    American family physician, 1984, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Bumetanide; Diltiazem; Dipeptides; Enalapril; Guanabenz; Guanidines; Humans; Indapamide; Labetalol; Nifedipine; Pindolol; Verapamil

1984
Local anaesthetic effect of antiarrhythmic drugs and human sperm immobilization: mechanism and application of the interrelationship.
    British journal of clinical pharmacology, 1984, Volume: 17, Issue:6

    Topics: Anesthetics, Local; Anti-Arrhythmia Agents; Diltiazem; Humans; Labetalol; Male; Mexiletine; Procainamide; Quinidine; Sperm Immobilizing Agents

1984
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Effects of labetalol on hemodynamic parameters and soluble biomarkers of inflammation in acute coronary syndrome in patients with active cocaine use.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:1

    Topics: Acute Coronary Syndrome; Adrenergic alpha-Antagonists; Adult; Aged; Biomarkers; Cardiovascular Agents; CD40 Ligand; Cocaine-Related Disorders; Diltiazem; Female; Georgia; Hemodynamics; Humans; Inflammation; Interleukin-6; Labetalol; Male; Middle Aged; Treatment Outcome

2010
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146

    Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan

2020