Page last updated: 2024-08-23

diltiazem and ketanserin

diltiazem has been researched along with ketanserin in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's8 (33.33)18.2507
2000's2 (8.33)29.6817
2010's8 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K1
Carmody, LC; Dandapani, S; Donckele, E; Feng, Y; Fernandez, C; Germain, AR; Gupta, PB; Lander, ES; Morgan, B; Munoz, B; Nag, PP; Palmer, M; Perez, JR; Schreiber, SL; Verplank, L1
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Egashira, K; Hayashi, Y; Nakamura, M; Takeshita, A; Tomoike, H; Yamada, A1
Mustafa, AA1
Fernandez-Alfonso, MS; Guerra, P; Marín, J; Reviriego, J1
Kienast, J; Verstraete, M1
Masuyama, Y; Nishio, I; Tsuda, K1
Chiba, S; Sinanović, O1
Andersson, TL; Larsson, B; Vinge, E1
Chiba, S; Tsuji, T2
Chiba, S; Vhora, S1
Lund-Johansen, P; Omvik, P1
Chiba, S; Nakane, T; Noguchi, M1
Beaughard, M; Brasset, M; John, G; Massingham, R1
Marwood, JF; Okoro, EO1

Reviews

1 review(s) available for diltiazem and ketanserin

ArticleYear
Pharmacology of the interaction between platelets and vessel wall.
    Clinics in haematology, 1986, Volume: 15, Issue:2

    Topics: Animals; Aspirin; Blood Platelets; Blood Vessels; Dextrans; Diltiazem; Dipyridamole; Epoprostenol; Humans; Imidazoles; Ketanserin; Piperidines; Pyrazoles; Pyrazolones; Sulfinpyrazone; Sulfonamides; Thiophenes; Ticlopidine

1986

Other Studies

23 other study(ies) available for diltiazem and ketanserin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, Liver; Neuralgia; Nociceptin Receptor; Pyrroles; Rats; Receptors, Opioid; Structure-Activity Relationship

2010
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
    Bioorganic & medicinal chemistry letters, 2013, Mar-15, Volume: 23, Issue:6

    Topics: Amides; Breast Neoplasms; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Neoplastic Stem Cells; Small Molecule Libraries; Structure-Activity Relationship

2013
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Mechanism of ergonovine-induced hyperconstriction of the large epicardial coronary artery in conscious dogs a month after arterial injury.
    Circulation research, 1992, Volume: 71, Issue:2

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vasospasm; Coronary Vessels; Diltiazem; Dogs; Electrophysiology; Endothelium, Vascular; Ergonovine; Heart Rate; Indomethacin; Ketanserin; Methysergide; Phenylephrine; Prazosin; Receptors, Serotonin

1992
Rapid desensitization of central beta-adrenoceptors in rat after subacute treatment with imipramine and calcium entry blockers.
    Neuropharmacology, 1991, Volume: 30, Issue:8

    Topics: 1-Propanol; Animals; Calcium Channel Blockers; Clonidine; Diltiazem; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drinking Behavior; Fenclonine; Imipramine; Isoproterenol; Ketanserin; Nicardipine; Nifedipine; Oxidopamine; Rats; Receptors, Adrenergic, beta; Verapamil

1991
Effects of Ca2+ antagonists nifedipine and diltiazem on isolated human chorionic arteries and veins.
    Journal of cardiovascular pharmacology, 1990, Volume: 16, Issue:1

    Topics: Arteries; Calcium; Calcium Radioisotopes; Diltiazem; Female; Humans; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Placenta; Potassium; Prazosin; Pregnancy; Regional Blood Flow; Serotonin; Veins

1990
Effects of ketanserin, verapamil and diltiazem on vascular sympathetic nerve activity in hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1989, Volume: 11 Suppl 1

    Topics: Animals; Blood Pressure; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; Hypertension; Ketanserin; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Verapamil

1989
Pharmacological analysis of 5-HT-induced vasoconstriction in isolated, perfused dog skeletal muscle arteries.
    European journal of pharmacology, 1987, Nov-17, Volume: 143, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Arteries; Cold Temperature; Diltiazem; Dogs; Female; In Vitro Techniques; Ketanserin; Male; Methysergide; Muscle, Smooth, Vascular; Norepinephrine; Potassium Chloride; Quinazolines; Serotonin; Vasoconstriction

1987
Effects of some calcium antagonists on aggregation by adrenalin and serotonin and on alpha-adrenoceptor radioligand binding in human platelets.
    Acta physiologica Scandinavica, 1988, Volume: 133, Issue:3

    Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Diltiazem; Epinephrine; Humans; Ketanserin; Nifedipine; Phentolamine; Platelet Aggregation; Radioligand Assay; Serotonin; Verapamil; Yohimbine

1988
Vasoconstrictor mechanism of 5-hydroxytryptamine in isolated and perfused canine basilar arteries.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 286, Issue:1

    Topics: Animals; Basilar Artery; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; Ketanserin; Male; Methysergide; Potassium Chloride; Receptors, Serotonin; Saponins; Serotonin; Vasoconstriction

1987
Mechanism of vascular responsiveness to barbiturates in isolated and perfused canine basilar arteries.
    Neurosurgery, 1987, Volume: 21, Issue:2

    Topics: Animals; Barbiturates; Basilar Artery; Calcium; Diltiazem; Dogs; Female; In Vitro Techniques; Ketanserin; Male; Norepinephrine; Phentolamine; Saponins; Serotonin; Thiopental; Vasoconstriction; Vasodilation

1987
Functional 5-HT receptor subtypes in the isolated canine common carotid artery.
    Heart and vessels, 1994, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Antagonists; Animals; Carotid Artery, Common; Diltiazem; Dogs; Female; Ketanserin; Male; Methysergide; Norepinephrine; Potassium Chloride; Quinazolines; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spiperone; Vasoconstriction

1994
Long-term hemodynamic effects at rest and during exercise of newer antihypertensive agents and salt restriction in essential hypertension: review of epanolol, doxazosin, amlodipine, felodipine, diltiazem, lisinopril, dilevalol, carvedilol, and ketanserin.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Benzeneacetamides; Carbazoles; Carvedilol; Diet, Sodium-Restricted; Diltiazem; Dipeptides; Doxazosin; Exercise; Felodipine; Female; Hemodynamics; Humans; Hypertension; Ketanserin; Labetalol; Lisinopril; Longitudinal Studies; Male; Middle Aged; Propanolamines

1993
Characterization of 5-HT receptors in simian isolated gastroepiploic artery.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: Animals; Arteries; Diltiazem; Endothelium, Vascular; Female; In Vitro Techniques; Ketanserin; Macaca; Male; Methysergide; Norepinephrine; Omentum; Perfusion; Phentolamine; Potassium Chloride; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Stomach; Vasoconstriction

1993
Failure of calcium channel blockade to reduce platelet-mediated cyclic flow variations in dogs with coronary stenosis and endothelial injury.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:4

    Topics: Animals; Aspirin; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Diltiazem; Disease Models, Animal; Dogs; Endothelium, Vascular; Female; Heart Block; Infusions, Intravenous; Ketanserin; Male; Nifedipine; Platelet Aggregation; Platelet Aggregation Inhibitors; Thrombosis; Vasodilator Agents; Verapamil

1995
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997